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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CPT2-SCP2 (FusionGDB2 ID:19241)

Fusion Gene Summary for CPT2-SCP2

check button Fusion gene summary
Fusion gene informationFusion gene name: CPT2-SCP2
Fusion gene ID: 19241
HgeneTgene
Gene symbol

CPT2

SCP2

Gene ID

1376

10388

Gene namecarnitine palmitoyltransferase 2synaptonemal complex protein 2
SynonymsCPT1|CPTASE|IIAE4SCP-2|SCP2|SPGF1
Cytomap

1p32.3

20q13.33

Type of geneprotein-codingprotein-coding
Descriptioncarnitine O-palmitoyltransferase 2, mitochondrialCPT IIcarnitine palmitoyltransferase IItesticular secretory protein Li 13synaptonemal complex protein 2synaptonemal complex lateral element protein
Modification date2020031320200313
UniProtAcc

P23786

Q9BR46

Ensembl transtripts involved in fusion geneENST00000371486, ENST00000468572, 
ENST00000408941, ENST00000430330, 
ENST00000435345, ENST00000473584, 
ENST00000488965, ENST00000371509, 
ENST00000371513, ENST00000371514, 
ENST00000407246, ENST00000528311, 
Fusion gene scores* DoF score2 X 2 X 2=84 X 4 X 4=64
# samples 24
** MAII scorelog2(2/8*10)=1.32192809488736log2(4/64*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CPT2 [Title/Abstract] AND SCP2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCPT2(53676991)-SCP2(53420412), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CPT2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SCP2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-NJ-A4YF-01ACPT2chr1

53676991

-SCP2chr1

53420412

+


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Fusion Gene ORF analysis for CPT2-SCP2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000371486ENST00000408941CPT2chr1

53676991

-SCP2chr1

53420412

+
5CDS-intronENST00000371486ENST00000430330CPT2chr1

53676991

-SCP2chr1

53420412

+
5CDS-intronENST00000371486ENST00000435345CPT2chr1

53676991

-SCP2chr1

53420412

+
5CDS-intronENST00000371486ENST00000473584CPT2chr1

53676991

-SCP2chr1

53420412

+
5CDS-intronENST00000371486ENST00000488965CPT2chr1

53676991

-SCP2chr1

53420412

+
In-frameENST00000371486ENST00000371509CPT2chr1

53676991

-SCP2chr1

53420412

+
In-frameENST00000371486ENST00000371513CPT2chr1

53676991

-SCP2chr1

53420412

+
In-frameENST00000371486ENST00000371514CPT2chr1

53676991

-SCP2chr1

53420412

+
In-frameENST00000371486ENST00000407246CPT2chr1

53676991

-SCP2chr1

53420412

+
In-frameENST00000371486ENST00000528311CPT2chr1

53676991

-SCP2chr1

53420412

+
intron-3CDSENST00000468572ENST00000371509CPT2chr1

53676991

-SCP2chr1

53420412

+
intron-3CDSENST00000468572ENST00000371513CPT2chr1

53676991

-SCP2chr1

53420412

+
intron-3CDSENST00000468572ENST00000371514CPT2chr1

53676991

-SCP2chr1

53420412

+
intron-3CDSENST00000468572ENST00000407246CPT2chr1

53676991

-SCP2chr1

53420412

+
intron-3CDSENST00000468572ENST00000528311CPT2chr1

53676991

-SCP2chr1

53420412

+
intron-intronENST00000468572ENST00000408941CPT2chr1

53676991

-SCP2chr1

53420412

+
intron-intronENST00000468572ENST00000430330CPT2chr1

53676991

-SCP2chr1

53420412

+
intron-intronENST00000468572ENST00000435345CPT2chr1

53676991

-SCP2chr1

53420412

+
intron-intronENST00000468572ENST00000473584CPT2chr1

53676991

-SCP2chr1

53420412

+
intron-intronENST00000468572ENST00000488965CPT2chr1

53676991

-SCP2chr1

53420412

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000371486CPT2chr153676991-ENST00000371514SCP2chr153420412+4472216042834721014
ENST00000371486CPT2chr153676991-ENST00000528311SCP2chr153420412+3672216042834721014
ENST00000371486CPT2chr153676991-ENST00000371509SCP2chr153420412+3739216042834721014
ENST00000371486CPT2chr153676991-ENST00000407246SCP2chr153420412+4029216042834721014
ENST00000371486CPT2chr153676991-ENST00000371513SCP2chr153420412+388521604282929833

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000371486ENST00000371514CPT2chr153676991-SCP2chr153420412+0.0008094640.9991905
ENST00000371486ENST00000528311CPT2chr153676991-SCP2chr153420412+0.0022668250.9977331
ENST00000371486ENST00000371509CPT2chr153676991-SCP2chr153420412+0.0020229260.9979771
ENST00000371486ENST00000407246CPT2chr153676991-SCP2chr153420412+0.0015066720.9984933
ENST00000371486ENST00000371513CPT2chr153676991-SCP2chr153420412+0.0019528310.9980471

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Fusion Genomic Features for CPT2-SCP2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CPT2-SCP2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:53676991/chr1:53420412)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CPT2

P23786

SCP2

Q9BR46

FUNCTION: Involved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites (PubMed:20538056, PubMed:24780397). Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidation, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Active with medium (C8-C12) and long-chain (C14-C18) acyl-CoA esters (PubMed:20538056). {ECO:0000269|PubMed:20538056, ECO:0000269|PubMed:24780397}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCPT2chr1:53676991chr1:53420412ENST00000371486-45179_208548659.0IntramembraneNote%3DMitochondrial inner membrane
HgeneCPT2chr1:53676991chr1:53420412ENST00000371486-45452_464548659.0RegionCoenzyme A binding
HgeneCPT2chr1:53676991chr1:53420412ENST00000371486-4526_178548659.0Topological domainMitochondrial matrix
TgeneSCP2chr1:53676991chr1:53420412ENST00000371509215433_54366504.0DomainNote=SCP2
TgeneSCP2chr1:53676991chr1:53420412ENST00000371513211433_54366323.0DomainNote=SCP2
TgeneSCP2chr1:53676991chr1:53420412ENST00000371514316433_543110548.0DomainNote=SCP2
TgeneSCP2chr1:53676991chr1:53420412ENST00000407246215433_54386524.0DomainNote=SCP2
TgeneSCP2chr1:53676991chr1:53420412ENST0000040894104433_5430361.0DomainNote=SCP2
TgeneSCP2chr1:53676991chr1:53420412ENST0000043033005433_5430141.0DomainNote=SCP2
TgeneSCP2chr1:53676991chr1:53420412ENST0000043534505433_5430144.0DomainNote=SCP2
TgeneSCP2chr1:53676991chr1:53420412ENST0000048896503433_543060.0DomainNote=SCP2
TgeneSCP2chr1:53676991chr1:53420412ENST00000528311215433_54329467.0DomainNote=SCP2
TgeneSCP2chr1:53676991chr1:53420412ENST00000371509215545_54766504.0MotifMicrobody targeting signal
TgeneSCP2chr1:53676991chr1:53420412ENST00000371513211545_54766323.0MotifMicrobody targeting signal
TgeneSCP2chr1:53676991chr1:53420412ENST00000371514316545_547110548.0MotifMicrobody targeting signal
TgeneSCP2chr1:53676991chr1:53420412ENST00000407246215545_54786524.0MotifMicrobody targeting signal
TgeneSCP2chr1:53676991chr1:53420412ENST0000040894104545_5470361.0MotifMicrobody targeting signal
TgeneSCP2chr1:53676991chr1:53420412ENST0000043033005545_5470141.0MotifMicrobody targeting signal
TgeneSCP2chr1:53676991chr1:53420412ENST0000043534505545_5470144.0MotifMicrobody targeting signal
TgeneSCP2chr1:53676991chr1:53420412ENST0000048896503545_547060.0MotifMicrobody targeting signal
TgeneSCP2chr1:53676991chr1:53420412ENST00000528311215545_54729467.0MotifMicrobody targeting signal

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCPT2chr1:53676991chr1:53420412ENST00000371486-45209_658548659.0Topological domainMitochondrial matrix


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Fusion Gene Sequence for CPT2-SCP2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>19241_19241_1_CPT2-SCP2_CPT2_chr1_53676991_ENST00000371486_SCP2_chr1_53420412_ENST00000371509_length(transcript)=3739nt_BP=2160nt
CTCATATCTAGAATTTTGGGAGGTACTTTGAATCATTACGATCTATCTACTTCTTAGGTGAGGAAATAGAGGTTTAAAATTTAGTCCACA
GTCTCGCAAGGATGGAGCCTGGATCAAATTTTGGGTTATCAGATTCCAATCACGTTTCTTAGCTTTTCTTTTTTTTTTCCAACTCCAGTT
TCTGTCTTGCTCCAAAAAAGGGGAAGGAGCGGCTGCGGCGCTCGGTTTCCCGCCTCCTAGGGAAGGGAAGGGAGACGAGCAGCGCGGAGG
CTGGGGCCCCCTTCCGGGCGGGGCCTACTAGTGGGCGGGGCCTGTCAGTGAGCGGCCCCTGCCCGGAAGGAGCCAGTCCGGGGCGGAGCC
GATGGCCTTACAGGGGCCGGAAGTGGCCTGCGGGCGGAGAAGTGCCTCAGGAGTCCTGACGCAGTGTCTTGGGCGCTAACGGCGGCGGCG
GCCTTGTGTTTAGACTCCAGAACTCCCCACTTGCCGCGTTCTCGCCGCCGCAGGCTCCCGGGACGATGGTGCCCCGCCTGCTGCTGCGCG
CCTGGCCCCGGGGCCCCGCGGTTGGTCCGGGAGCCCCCAGTCGGCCCCTCAGCGCCGGCTCCGGGCCCGGCCAGTACCTGCAGCGCAGCA
TCGTGCCCACCATGCACTACCAGGACAGCCTGCCCAGGCTGCCTATTCCCAAACTTGAAGACACCATTAGGAGATACCTCAGTGCACAGA
AGCCTCTCTTGAATGATGGCCAGTTCAGGAAAACAGAACAATTTTGCAAGAGTTTTGAAAATGGGATTGGAAAAGAACTGCATGAGCAGC
TGGTTGCTCTGGACAAACAGAATAAACATACAAGCTACATTTCGGGACCCTGGTTTGATATGTACCTATCTGCTCGAGACTCCGTTGTTC
TGAACTTTAATCCATTTATGGCTTTCAATCCTGACCCAAAATCTGAGTATAATGACCAGCTCACCCGGGCAACCAACATGACTGTTTCTG
CCATCCGGTTTCTGAAGACACTCCGGGCTGGCCTTCTGGAGCCAGAAGTGTTCCACTTGAACCCTGCAAAAAGTGACACTATCACCTTCA
AGAGACTCATACGCTTTGTGCCTTCCTCTCTGTCCTGGTATGGGGCCTACCTGGTCAATGCGTATCCCCTGGATATGTCCCAGTATTTTC
GGCTTTTCAACTCAACTCGTTTACCCAAACCCAGTCGGGATGAACTCTTCACTGATGACAAGGCCAGACACCTCCTGGTCCTAAGGAAAG
GAAATTTTTATATCTTTGATGTCCTGGATCAAGATGGGAACATTGTGAGCCCCTCGGAAATCCAGGCACATCTGAAGTACATTCTCTCAG
ACAGCAGCCCCGCCCCCGAGTTTCCCCTGGCATACCTGACCAGTGAGAACCGAGACATCTGGGCAGAGCTCAGGCAGAAGCTGATGAGTA
GTGGCAATGAGGAGAGCCTGAGGAAAGTGGACTCGGCAGTGTTCTGTCTCTGCCTAGATGACTTCCCCATTAAGGACCTTGTCCACTTGT
CCCACAATATGCTGCATGGGGATGGCACAAACCGCTGGTTTGATAAATCCTTTAACCTCATTATCGCCAAGGATGGCTCTACTGCCGTCC
ACTTTGAGCACTCTTGGGGTGATGGTGTGGCAGTGCTCAGATTTTTTAATGAAGTATTTAAAGACAGCACTCAGACCCCTGCCGTCACTC
CACAGAGCCAGCCAGCTACCACTGACTCTACTGTCACGGTGCAGAAACTCAACTTCGAGCTGACTGATGCCTTAAAGACTGGCATCACAG
CTGCTAAGGAAAAGTTTGATGCCACCATGAAAACCCTCACTATTGACTGCGTCCAGTTTCAGAGAGGAGGCAAAGAATTCCTGAAGAAGC
AAAAGCTGAGCCCTGACGCAGTTGCCCAGCTGGCATTCCAGATGGCCTTCCTGCGGCAGTACGGGCAGACAGTGGCCACCTACGAGTCCT
GTAGCACTGCCGCATTCAAGCACGGCCGCACTGAGACCATCCGCCCGGCCTCCGTCTATACAAAGAGGTGCTCTGAGGCCTTTGTCAGGG
AGCCCTCCAGGCACAGTGCTGGTGAGCTTCAGCAGATGATGGTTGAGTGCTCCAAGTACCATGGCCAGCTGACCAAAGAAGCAGCAATGG
GTGTGGCAGAATGTGTCTTGGCTCTTGGGTTTGAGAAGATGAGTAAGGGAAGCCTTGGAATAAAATTTTCAGATAGAACCATTCCCACTG
ATAAGCATGTTGACCTCCTGATCAATAAGTATGGATTGTCTGCTCACCCAGTTGCTCCTCAGATGTTTGGGTATGCTGGAAAAGAACATA
TGGAAAAATATGGAACAAAAATTGAACACTTTGCAAAAATTGGATGGAAAAATCATAAACATTCAGTTAATAACCCGTATTCCCAGTTCC
AAGATGAATACAGTTTAGATGAAGTGATGGCATCTAAAGAAGTTTTTGATTTTTTGACTATCTTACAATGTTGTCCCACTTCAGATGGTG
CTGCAGCAGCAATTTTGGCCAGTGAAGCATTTGTACAGAAGTATGGCCTGCAATCCAAAGCTGTGGAAATTTTGGCACAAGAAATGATGA
CTGATTTGCCAAGCTCGTTTGAAGAAAAAAGCATTATTAAAATGGTTGGCTTTGATATGAGTAAAGAAGCTGCAAGAAAATGCTATGAGA
AATCTGGCCTGACACCAAATGATATTGACGTAATAGAACTTCACGATTGCTTTTCTACCAACGAACTCCTTACTTATGAAGCACTGGGAC
TCTGTCCAGAAGGACAAGGTGCAACGCTGGTTGATAGAGGAGATAATACATATGGAGGAAAGTGGGTCATAAATCCTAGTGGTGGACTGA
TTTCAAAGGGACACCCACTAGGCGCTACAGGTCTTGCTCAGTGTGCAGAACTCTGCTGGCAGCTGAGAGGGGAAGCCGGAAAGAGGCAAG
TTCCTGGTGCAAAGGTGGCTCTGCAGCATAATTTAGGCATTGGAGGAGCTGTGGTTGTAACACTCTACAAGATGGGTTTTCCGGAAGCCG
CCAGTTCTTTTAGAACTCATCAAATTGAAGCTGTTCCAACCAGCTCTGCAAGTGATGGATTTAAGGCAAATCTTGTTTTTAAGGAGATTG
AGAAGAAACTTGAAGAGGAAGGGGAACAGTTTGTGAAGAAAATCGGTGGTATTTTTGCCTTCAAGGTGAAAGATGGCCCTGGGGGTAAAG
AGGCCACCTGGGTGGTGGATGTGAAGAATGGCAAAGGATCAGTGCTTCCTAACTCAGATAAGAAGGCTGACTGCACAATCACAATGGCTG
ACTCAGACTTCCTGGCTTTAATGACTGGTAAAATGAATCCTCAGTCGGCCTTCTTTCAAGGCAAATTGAAAATCACTGGCAACATGGGTC
TCGCTATGAAGTTACAAAATCTTCAGCTTCAGCCAGGCAACGCTAAGCTCTGAAGAACTCCCTTTGGCTACTTTTGAAAATCAAGATGAG
ATATATAGATATATATCCATACATTTTATTGTCAGAATTTAGACTGAAACTACACATTGGCAAATAGCGTGGGATAGATTTGTTTCTTAA
TGGGTGTGACCAATCCTGTTTTTCCTATGCTCTGGGTGAATAGAGCCTGATGGTATACTACTGCTTTGCGGAATTGCATACAACTGTGCA

>19241_19241_1_CPT2-SCP2_CPT2_chr1_53676991_ENST00000371486_SCP2_chr1_53420412_ENST00000371509_length(amino acids)=1014AA_BP=577
MGANGGGGLVFRLQNSPLAAFSPPQAPGTMVPRLLLRAWPRGPAVGPGAPSRPLSAGSGPGQYLQRSIVPTMHYQDSLPRLPIPKLEDTI
RRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDKQNKHTSYISGPWFDMYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTR
ATNMTVSAIRFLKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRLPKPSRDELFTDDKAR
HLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPAPEFPLAYLTSENRDIWAELRQKLMSSGNEESLRKVDSAVFCLCLDDFP
IKDLVHLSHNMLHGDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVFKDSTQTPAVTPQSQPATTDSTVTVQKLNFELTD
ALKTGITAAKEKFDATMKTLTIDCVQFQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASVYTKR
CSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGVAECVLALGFEKMSKGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMF
GYAGKEHMEKYGTKIEHFAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEAFVQKYGLQSKAVE
ILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDIDVIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWV
INPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVPGAKVALQHNLGIGGAVVVTLYKMGFPEAASSFRTHQIEAVPTSSASDGFKA
NLVFKEIEKKLEEEGEQFVKKIGGIFAFKVKDGPGGKEATWVVDVKNGKGSVLPNSDKKADCTITMADSDFLALMTGKMNPQSAFFQGKL

--------------------------------------------------------------
>19241_19241_2_CPT2-SCP2_CPT2_chr1_53676991_ENST00000371486_SCP2_chr1_53420412_ENST00000371513_length(transcript)=3885nt_BP=2160nt
CTCATATCTAGAATTTTGGGAGGTACTTTGAATCATTACGATCTATCTACTTCTTAGGTGAGGAAATAGAGGTTTAAAATTTAGTCCACA
GTCTCGCAAGGATGGAGCCTGGATCAAATTTTGGGTTATCAGATTCCAATCACGTTTCTTAGCTTTTCTTTTTTTTTTCCAACTCCAGTT
TCTGTCTTGCTCCAAAAAAGGGGAAGGAGCGGCTGCGGCGCTCGGTTTCCCGCCTCCTAGGGAAGGGAAGGGAGACGAGCAGCGCGGAGG
CTGGGGCCCCCTTCCGGGCGGGGCCTACTAGTGGGCGGGGCCTGTCAGTGAGCGGCCCCTGCCCGGAAGGAGCCAGTCCGGGGCGGAGCC
GATGGCCTTACAGGGGCCGGAAGTGGCCTGCGGGCGGAGAAGTGCCTCAGGAGTCCTGACGCAGTGTCTTGGGCGCTAACGGCGGCGGCG
GCCTTGTGTTTAGACTCCAGAACTCCCCACTTGCCGCGTTCTCGCCGCCGCAGGCTCCCGGGACGATGGTGCCCCGCCTGCTGCTGCGCG
CCTGGCCCCGGGGCCCCGCGGTTGGTCCGGGAGCCCCCAGTCGGCCCCTCAGCGCCGGCTCCGGGCCCGGCCAGTACCTGCAGCGCAGCA
TCGTGCCCACCATGCACTACCAGGACAGCCTGCCCAGGCTGCCTATTCCCAAACTTGAAGACACCATTAGGAGATACCTCAGTGCACAGA
AGCCTCTCTTGAATGATGGCCAGTTCAGGAAAACAGAACAATTTTGCAAGAGTTTTGAAAATGGGATTGGAAAAGAACTGCATGAGCAGC
TGGTTGCTCTGGACAAACAGAATAAACATACAAGCTACATTTCGGGACCCTGGTTTGATATGTACCTATCTGCTCGAGACTCCGTTGTTC
TGAACTTTAATCCATTTATGGCTTTCAATCCTGACCCAAAATCTGAGTATAATGACCAGCTCACCCGGGCAACCAACATGACTGTTTCTG
CCATCCGGTTTCTGAAGACACTCCGGGCTGGCCTTCTGGAGCCAGAAGTGTTCCACTTGAACCCTGCAAAAAGTGACACTATCACCTTCA
AGAGACTCATACGCTTTGTGCCTTCCTCTCTGTCCTGGTATGGGGCCTACCTGGTCAATGCGTATCCCCTGGATATGTCCCAGTATTTTC
GGCTTTTCAACTCAACTCGTTTACCCAAACCCAGTCGGGATGAACTCTTCACTGATGACAAGGCCAGACACCTCCTGGTCCTAAGGAAAG
GAAATTTTTATATCTTTGATGTCCTGGATCAAGATGGGAACATTGTGAGCCCCTCGGAAATCCAGGCACATCTGAAGTACATTCTCTCAG
ACAGCAGCCCCGCCCCCGAGTTTCCCCTGGCATACCTGACCAGTGAGAACCGAGACATCTGGGCAGAGCTCAGGCAGAAGCTGATGAGTA
GTGGCAATGAGGAGAGCCTGAGGAAAGTGGACTCGGCAGTGTTCTGTCTCTGCCTAGATGACTTCCCCATTAAGGACCTTGTCCACTTGT
CCCACAATATGCTGCATGGGGATGGCACAAACCGCTGGTTTGATAAATCCTTTAACCTCATTATCGCCAAGGATGGCTCTACTGCCGTCC
ACTTTGAGCACTCTTGGGGTGATGGTGTGGCAGTGCTCAGATTTTTTAATGAAGTATTTAAAGACAGCACTCAGACCCCTGCCGTCACTC
CACAGAGCCAGCCAGCTACCACTGACTCTACTGTCACGGTGCAGAAACTCAACTTCGAGCTGACTGATGCCTTAAAGACTGGCATCACAG
CTGCTAAGGAAAAGTTTGATGCCACCATGAAAACCCTCACTATTGACTGCGTCCAGTTTCAGAGAGGAGGCAAAGAATTCCTGAAGAAGC
AAAAGCTGAGCCCTGACGCAGTTGCCCAGCTGGCATTCCAGATGGCCTTCCTGCGGCAGTACGGGCAGACAGTGGCCACCTACGAGTCCT
GTAGCACTGCCGCATTCAAGCACGGCCGCACTGAGACCATCCGCCCGGCCTCCGTCTATACAAAGAGGTGCTCTGAGGCCTTTGTCAGGG
AGCCCTCCAGGCACAGTGCTGGTGAGCTTCAGCAGATGATGGTTGAGTGCTCCAAGTACCATGGCCAGCTGACCAAAGAAGCAGCAATGG
GTGTGGCAGAATGTGTCTTGGCTCTTGGGTTTGAGAAGATGAGTAAGGGAAGCCTTGGAATAAAATTTTCAGATAGAACCATTCCCACTG
ATAAGCATGTTGACCTCCTGATCAATAAGTATGGATTGTCTGCTCACCCAGTTGCTCCTCAGATGTTTGGGTATGCTGGAAAAGAACATA
TGGAAAAATATGGAACAAAAATTGAACACTTTGCAAAAATTGGATGGAAAAATCATAAACATTCAGTTAATAACCCGTATTCCCAGTTCC
AAGATGAATACAGTTTAGATGAAGTGATGGCATCTAAAGAAGTTTTTGATTTTTTGACTATCTTACAATGTTGTCCCACTTCAGATGGTG
CTGCAGCAGCAATTTTGGCCAGTGAAGCATTTGTACAGAAGTATGGCCTGCAATCCAAAGCTGTGGAAATTTTGGCACAAGAAATGATGA
CTGATTTGCCAAGCTCGTTTGAAGAAAAAAGCATTATTAAAATGGTTGGCTTTGATATGAGTAAAGAAGCTGCAAGAAAATGCTATGAGA
AATCTGGCCTGACACCAAATGATATTGACGTAATAGAACTTCACGATTGCTTTTCTACCAACGAACTCCTTACTTATGAAGCACTGGGAC
TCTGTCCAGAAGGACAAGGTGCAACGCTGGTTGATAGAGGAGATAATACATATGGAGGAAAGTGGGTCATAAATCCTAGTGGTGGACTGA
TTTCAAAGGGACACCCACTAGGCGCTACAGGAGGACATTCCTGCTCTTGAAATTTCCTGATAACCCGGACAAGTTCATGGAAAGCTTGAT
CTACATTCATCCTAATCTTTGCTGATGCCTCCATGTATGTTACCTTAAGTTGCCGTGCTAACTGCCGTCCTTCTTCCTGTGTTACCTGTC
TTTGATGATCCAGATCTGCTTTATTACCAATTAAAATCATTGGGAACTCATCACGATCCTTTACTCTGAGAATCTGTCTTTGAAACTTAT
AGATTTCTTCAAAACTGCCTCTATCTGTGACTGAAAAGACCAACAGGAAGCCCTCGCCAGTCCTCATATACTGTTCTCTCATGGCTCCAA
GCTCTTCTTGTCCTGCTGTATCCAAAATATCTAGCCGGGCTGCTCTGTCATCTATCACACACTGCTTTGTGTAAGAATCTTCATTGGTTG
GATCATAATCCGTTACAAAATAGGACTCCCAACTTAGGAAACAAAACATTTGTAATATGATTGAAGACTCCTGCATGCCTCCTCAATAAT
ATTCCCCTCTCTCCTCCCCCAGCACCAAGAGGTAATCAATATCCTGAATTTGGTATCTGTCATTCTCATGCATTTATACAACATTAGTAA
TCATATGATAGTATTCCTAAGCTATGTTTTGGAGAGGACACCACTGCAAATCTTCAGCCCTATACTAGCTTTTATCGGTAGCCATCAATT
GCAGTTTTAATAGAAATACAAATACATCAAGTGTCTGTTCTTTAATTTGTAAAGAAAATTTGTTTTCTAGCGTGACACCCTCAAGGTACC
GTATCTGTATGTAAATGTTGTGCCCAATGCTACACAGACATTATTTTAAAACTATTTTCTGCCTTTGGTAAATAGACTAAACTGTTTTCT
TTATTCCTCAAAAGAATTAGATCATACTTCAGTGTTGATTTTGTTGCTAATGGGACATGGAGATGTCTGGATGATAATAAATATTCCTGT

>19241_19241_2_CPT2-SCP2_CPT2_chr1_53676991_ENST00000371486_SCP2_chr1_53420412_ENST00000371513_length(amino acids)=833AA_BP=577
MGANGGGGLVFRLQNSPLAAFSPPQAPGTMVPRLLLRAWPRGPAVGPGAPSRPLSAGSGPGQYLQRSIVPTMHYQDSLPRLPIPKLEDTI
RRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDKQNKHTSYISGPWFDMYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTR
ATNMTVSAIRFLKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRLPKPSRDELFTDDKAR
HLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPAPEFPLAYLTSENRDIWAELRQKLMSSGNEESLRKVDSAVFCLCLDDFP
IKDLVHLSHNMLHGDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVFKDSTQTPAVTPQSQPATTDSTVTVQKLNFELTD
ALKTGITAAKEKFDATMKTLTIDCVQFQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASVYTKR
CSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGVAECVLALGFEKMSKGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMF
GYAGKEHMEKYGTKIEHFAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEAFVQKYGLQSKAVE
ILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDIDVIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWV

--------------------------------------------------------------
>19241_19241_3_CPT2-SCP2_CPT2_chr1_53676991_ENST00000371486_SCP2_chr1_53420412_ENST00000371514_length(transcript)=4472nt_BP=2160nt
CTCATATCTAGAATTTTGGGAGGTACTTTGAATCATTACGATCTATCTACTTCTTAGGTGAGGAAATAGAGGTTTAAAATTTAGTCCACA
GTCTCGCAAGGATGGAGCCTGGATCAAATTTTGGGTTATCAGATTCCAATCACGTTTCTTAGCTTTTCTTTTTTTTTTCCAACTCCAGTT
TCTGTCTTGCTCCAAAAAAGGGGAAGGAGCGGCTGCGGCGCTCGGTTTCCCGCCTCCTAGGGAAGGGAAGGGAGACGAGCAGCGCGGAGG
CTGGGGCCCCCTTCCGGGCGGGGCCTACTAGTGGGCGGGGCCTGTCAGTGAGCGGCCCCTGCCCGGAAGGAGCCAGTCCGGGGCGGAGCC
GATGGCCTTACAGGGGCCGGAAGTGGCCTGCGGGCGGAGAAGTGCCTCAGGAGTCCTGACGCAGTGTCTTGGGCGCTAACGGCGGCGGCG
GCCTTGTGTTTAGACTCCAGAACTCCCCACTTGCCGCGTTCTCGCCGCCGCAGGCTCCCGGGACGATGGTGCCCCGCCTGCTGCTGCGCG
CCTGGCCCCGGGGCCCCGCGGTTGGTCCGGGAGCCCCCAGTCGGCCCCTCAGCGCCGGCTCCGGGCCCGGCCAGTACCTGCAGCGCAGCA
TCGTGCCCACCATGCACTACCAGGACAGCCTGCCCAGGCTGCCTATTCCCAAACTTGAAGACACCATTAGGAGATACCTCAGTGCACAGA
AGCCTCTCTTGAATGATGGCCAGTTCAGGAAAACAGAACAATTTTGCAAGAGTTTTGAAAATGGGATTGGAAAAGAACTGCATGAGCAGC
TGGTTGCTCTGGACAAACAGAATAAACATACAAGCTACATTTCGGGACCCTGGTTTGATATGTACCTATCTGCTCGAGACTCCGTTGTTC
TGAACTTTAATCCATTTATGGCTTTCAATCCTGACCCAAAATCTGAGTATAATGACCAGCTCACCCGGGCAACCAACATGACTGTTTCTG
CCATCCGGTTTCTGAAGACACTCCGGGCTGGCCTTCTGGAGCCAGAAGTGTTCCACTTGAACCCTGCAAAAAGTGACACTATCACCTTCA
AGAGACTCATACGCTTTGTGCCTTCCTCTCTGTCCTGGTATGGGGCCTACCTGGTCAATGCGTATCCCCTGGATATGTCCCAGTATTTTC
GGCTTTTCAACTCAACTCGTTTACCCAAACCCAGTCGGGATGAACTCTTCACTGATGACAAGGCCAGACACCTCCTGGTCCTAAGGAAAG
GAAATTTTTATATCTTTGATGTCCTGGATCAAGATGGGAACATTGTGAGCCCCTCGGAAATCCAGGCACATCTGAAGTACATTCTCTCAG
ACAGCAGCCCCGCCCCCGAGTTTCCCCTGGCATACCTGACCAGTGAGAACCGAGACATCTGGGCAGAGCTCAGGCAGAAGCTGATGAGTA
GTGGCAATGAGGAGAGCCTGAGGAAAGTGGACTCGGCAGTGTTCTGTCTCTGCCTAGATGACTTCCCCATTAAGGACCTTGTCCACTTGT
CCCACAATATGCTGCATGGGGATGGCACAAACCGCTGGTTTGATAAATCCTTTAACCTCATTATCGCCAAGGATGGCTCTACTGCCGTCC
ACTTTGAGCACTCTTGGGGTGATGGTGTGGCAGTGCTCAGATTTTTTAATGAAGTATTTAAAGACAGCACTCAGACCCCTGCCGTCACTC
CACAGAGCCAGCCAGCTACCACTGACTCTACTGTCACGGTGCAGAAACTCAACTTCGAGCTGACTGATGCCTTAAAGACTGGCATCACAG
CTGCTAAGGAAAAGTTTGATGCCACCATGAAAACCCTCACTATTGACTGCGTCCAGTTTCAGAGAGGAGGCAAAGAATTCCTGAAGAAGC
AAAAGCTGAGCCCTGACGCAGTTGCCCAGCTGGCATTCCAGATGGCCTTCCTGCGGCAGTACGGGCAGACAGTGGCCACCTACGAGTCCT
GTAGCACTGCCGCATTCAAGCACGGCCGCACTGAGACCATCCGCCCGGCCTCCGTCTATACAAAGAGGTGCTCTGAGGCCTTTGTCAGGG
AGCCCTCCAGGCACAGTGCTGGTGAGCTTCAGCAGATGATGGTTGAGTGCTCCAAGTACCATGGCCAGCTGACCAAAGAAGCAGCAATGG
GTGTGGCAGAATGTGTCTTGGCTCTTGGGTTTGAGAAGATGAGTAAGGGAAGCCTTGGAATAAAATTTTCAGATAGAACCATTCCCACTG
ATAAGCATGTTGACCTCCTGATCAATAAGTATGGATTGTCTGCTCACCCAGTTGCTCCTCAGATGTTTGGGTATGCTGGAAAAGAACATA
TGGAAAAATATGGAACAAAAATTGAACACTTTGCAAAAATTGGATGGAAAAATCATAAACATTCAGTTAATAACCCGTATTCCCAGTTCC
AAGATGAATACAGTTTAGATGAAGTGATGGCATCTAAAGAAGTTTTTGATTTTTTGACTATCTTACAATGTTGTCCCACTTCAGATGGTG
CTGCAGCAGCAATTTTGGCCAGTGAAGCATTTGTACAGAAGTATGGCCTGCAATCCAAAGCTGTGGAAATTTTGGCACAAGAAATGATGA
CTGATTTGCCAAGCTCGTTTGAAGAAAAAAGCATTATTAAAATGGTTGGCTTTGATATGAGTAAAGAAGCTGCAAGAAAATGCTATGAGA
AATCTGGCCTGACACCAAATGATATTGACGTAATAGAACTTCACGATTGCTTTTCTACCAACGAACTCCTTACTTATGAAGCACTGGGAC
TCTGTCCAGAAGGACAAGGTGCAACGCTGGTTGATAGAGGAGATAATACATATGGAGGAAAGTGGGTCATAAATCCTAGTGGTGGACTGA
TTTCAAAGGGACACCCACTAGGCGCTACAGGTCTTGCTCAGTGTGCAGAACTCTGCTGGCAGCTGAGAGGGGAAGCCGGAAAGAGGCAAG
TTCCTGGTGCAAAGGTGGCTCTGCAGCATAATTTAGGCATTGGAGGAGCTGTGGTTGTAACACTCTACAAGATGGGTTTTCCGGAAGCCG
CCAGTTCTTTTAGAACTCATCAAATTGAAGCTGTTCCAACCAGCTCTGCAAGTGATGGATTTAAGGCAAATCTTGTTTTTAAGGAGATTG
AGAAGAAACTTGAAGAGGAAGGGGAACAGTTTGTGAAGAAAATCGGTGGTATTTTTGCCTTCAAGGTGAAAGATGGCCCTGGGGGTAAAG
AGGCCACCTGGGTGGTGGATGTGAAGAATGGCAAAGGATCAGTGCTTCCTAACTCAGATAAGAAGGCTGACTGCACAATCACAATGGCTG
ACTCAGACTTCCTGGCTTTAATGACTGGTAAAATGAATCCTCAGTCGGCCTTCTTTCAAGGCAAATTGAAAATCACTGGCAACATGGGTC
TCGCTATGAAGTTACAAAATCTTCAGCTTCAGCCAGGCAACGCTAAGCTCTGAAGAACTCCCTTTGGCTACTTTTGAAAATCAAGATGAG
ATATATAGATATATATCCATACATTTTATTGTCAGAATTTAGACTGAAACTACACATTGGCAAATAGCGTGGGATAGATTTGTTTCTTAA
TGGGTGTGACCAATCCTGTTTTTCCTATGCTCTGGGTGAATAGAGCCTGATGGTATACTACTGCTTTGCGGAATTGCATACAACTGTGCA
TTACAAAGTTAATATGGTAATTATGGTCTGGGGTAAAATTGAGTTTCAGAATAAAATTAGGAACAGTAAAATCCAAAGAACTATGTAAAC
AAAAAAGCTTTTGTTTTGCTTACAAAGTATATTTAAGGATTATTCTGCTGAAGATTCAGTTTAAGAGTTTTCCTTGGGAGAACTAAGTAA
GAAACACAATGCCAACAGCTGGCCAGTAATTAGTGTTGTGCACTTCATGTCATTAATCAATTTCTCAATAGTTCTTAAAATTAGTGAGAT
TAAAAATCTAAAAATTTTGCATTTCATGCTATCAGAAACAGTATTTTCTTCCCAAATCAAAATAAAAGAAATATGATCAGAGCTTGAACA
CAGGCTTATTTTTAAAATAAAAATATTTTTAACATGGGTTTCCTTATTGAAAAATCAGTGTATTAGTCATAAAACACCATCATTAAGAAT
AATTGAACAATAAAGTTTGCTTTCAGATGCAGTTTTCAAATTATAATCTCATTTCAATTTATAACGTTCTCAGTCCTTTGTTATAATTTT
CCTTTTTCATGTAAGTTTAATTATCTGCATTTATCTTTTTTCCTAGTTTTTCTAATACTAATGTTATTTCTTAAAATTCAGTGAGATATA
GGATAAAATAATGCTTTGAGAAGAATGTTTAATAGAAAATTAAAATAACTTTTTCTGGCCTCTCTTGTTTTTACTGTGTATGTTCTTGCT

>19241_19241_3_CPT2-SCP2_CPT2_chr1_53676991_ENST00000371486_SCP2_chr1_53420412_ENST00000371514_length(amino acids)=1014AA_BP=577
MGANGGGGLVFRLQNSPLAAFSPPQAPGTMVPRLLLRAWPRGPAVGPGAPSRPLSAGSGPGQYLQRSIVPTMHYQDSLPRLPIPKLEDTI
RRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDKQNKHTSYISGPWFDMYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTR
ATNMTVSAIRFLKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRLPKPSRDELFTDDKAR
HLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPAPEFPLAYLTSENRDIWAELRQKLMSSGNEESLRKVDSAVFCLCLDDFP
IKDLVHLSHNMLHGDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVFKDSTQTPAVTPQSQPATTDSTVTVQKLNFELTD
ALKTGITAAKEKFDATMKTLTIDCVQFQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASVYTKR
CSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGVAECVLALGFEKMSKGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMF
GYAGKEHMEKYGTKIEHFAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEAFVQKYGLQSKAVE
ILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDIDVIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWV
INPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVPGAKVALQHNLGIGGAVVVTLYKMGFPEAASSFRTHQIEAVPTSSASDGFKA
NLVFKEIEKKLEEEGEQFVKKIGGIFAFKVKDGPGGKEATWVVDVKNGKGSVLPNSDKKADCTITMADSDFLALMTGKMNPQSAFFQGKL

--------------------------------------------------------------
>19241_19241_4_CPT2-SCP2_CPT2_chr1_53676991_ENST00000371486_SCP2_chr1_53420412_ENST00000407246_length(transcript)=4029nt_BP=2160nt
CTCATATCTAGAATTTTGGGAGGTACTTTGAATCATTACGATCTATCTACTTCTTAGGTGAGGAAATAGAGGTTTAAAATTTAGTCCACA
GTCTCGCAAGGATGGAGCCTGGATCAAATTTTGGGTTATCAGATTCCAATCACGTTTCTTAGCTTTTCTTTTTTTTTTCCAACTCCAGTT
TCTGTCTTGCTCCAAAAAAGGGGAAGGAGCGGCTGCGGCGCTCGGTTTCCCGCCTCCTAGGGAAGGGAAGGGAGACGAGCAGCGCGGAGG
CTGGGGCCCCCTTCCGGGCGGGGCCTACTAGTGGGCGGGGCCTGTCAGTGAGCGGCCCCTGCCCGGAAGGAGCCAGTCCGGGGCGGAGCC
GATGGCCTTACAGGGGCCGGAAGTGGCCTGCGGGCGGAGAAGTGCCTCAGGAGTCCTGACGCAGTGTCTTGGGCGCTAACGGCGGCGGCG
GCCTTGTGTTTAGACTCCAGAACTCCCCACTTGCCGCGTTCTCGCCGCCGCAGGCTCCCGGGACGATGGTGCCCCGCCTGCTGCTGCGCG
CCTGGCCCCGGGGCCCCGCGGTTGGTCCGGGAGCCCCCAGTCGGCCCCTCAGCGCCGGCTCCGGGCCCGGCCAGTACCTGCAGCGCAGCA
TCGTGCCCACCATGCACTACCAGGACAGCCTGCCCAGGCTGCCTATTCCCAAACTTGAAGACACCATTAGGAGATACCTCAGTGCACAGA
AGCCTCTCTTGAATGATGGCCAGTTCAGGAAAACAGAACAATTTTGCAAGAGTTTTGAAAATGGGATTGGAAAAGAACTGCATGAGCAGC
TGGTTGCTCTGGACAAACAGAATAAACATACAAGCTACATTTCGGGACCCTGGTTTGATATGTACCTATCTGCTCGAGACTCCGTTGTTC
TGAACTTTAATCCATTTATGGCTTTCAATCCTGACCCAAAATCTGAGTATAATGACCAGCTCACCCGGGCAACCAACATGACTGTTTCTG
CCATCCGGTTTCTGAAGACACTCCGGGCTGGCCTTCTGGAGCCAGAAGTGTTCCACTTGAACCCTGCAAAAAGTGACACTATCACCTTCA
AGAGACTCATACGCTTTGTGCCTTCCTCTCTGTCCTGGTATGGGGCCTACCTGGTCAATGCGTATCCCCTGGATATGTCCCAGTATTTTC
GGCTTTTCAACTCAACTCGTTTACCCAAACCCAGTCGGGATGAACTCTTCACTGATGACAAGGCCAGACACCTCCTGGTCCTAAGGAAAG
GAAATTTTTATATCTTTGATGTCCTGGATCAAGATGGGAACATTGTGAGCCCCTCGGAAATCCAGGCACATCTGAAGTACATTCTCTCAG
ACAGCAGCCCCGCCCCCGAGTTTCCCCTGGCATACCTGACCAGTGAGAACCGAGACATCTGGGCAGAGCTCAGGCAGAAGCTGATGAGTA
GTGGCAATGAGGAGAGCCTGAGGAAAGTGGACTCGGCAGTGTTCTGTCTCTGCCTAGATGACTTCCCCATTAAGGACCTTGTCCACTTGT
CCCACAATATGCTGCATGGGGATGGCACAAACCGCTGGTTTGATAAATCCTTTAACCTCATTATCGCCAAGGATGGCTCTACTGCCGTCC
ACTTTGAGCACTCTTGGGGTGATGGTGTGGCAGTGCTCAGATTTTTTAATGAAGTATTTAAAGACAGCACTCAGACCCCTGCCGTCACTC
CACAGAGCCAGCCAGCTACCACTGACTCTACTGTCACGGTGCAGAAACTCAACTTCGAGCTGACTGATGCCTTAAAGACTGGCATCACAG
CTGCTAAGGAAAAGTTTGATGCCACCATGAAAACCCTCACTATTGACTGCGTCCAGTTTCAGAGAGGAGGCAAAGAATTCCTGAAGAAGC
AAAAGCTGAGCCCTGACGCAGTTGCCCAGCTGGCATTCCAGATGGCCTTCCTGCGGCAGTACGGGCAGACAGTGGCCACCTACGAGTCCT
GTAGCACTGCCGCATTCAAGCACGGCCGCACTGAGACCATCCGCCCGGCCTCCGTCTATACAAAGAGGTGCTCTGAGGCCTTTGTCAGGG
AGCCCTCCAGGCACAGTGCTGGTGAGCTTCAGCAGATGATGGTTGAGTGCTCCAAGTACCATGGCCAGCTGACCAAAGAAGCAGCAATGG
GTGTGGCAGAATGTGTCTTGGCTCTTGGGTTTGAGAAGATGAGTAAGGGAAGCCTTGGAATAAAATTTTCAGATAGAACCATTCCCACTG
ATAAGCATGTTGACCTCCTGATCAATAAGTATGGATTGTCTGCTCACCCAGTTGCTCCTCAGATGTTTGGGTATGCTGGAAAAGAACATA
TGGAAAAATATGGAACAAAAATTGAACACTTTGCAAAAATTGGATGGAAAAATCATAAACATTCAGTTAATAACCCGTATTCCCAGTTCC
AAGATGAATACAGTTTAGATGAAGTGATGGCATCTAAAGAAGTTTTTGATTTTTTGACTATCTTACAATGTTGTCCCACTTCAGATGGTG
CTGCAGCAGCAATTTTGGCCAGTGAAGCATTTGTACAGAAGTATGGCCTGCAATCCAAAGCTGTGGAAATTTTGGCACAAGAAATGATGA
CTGATTTGCCAAGCTCGTTTGAAGAAAAAAGCATTATTAAAATGGTTGGCTTTGATATGAGTAAAGAAGCTGCAAGAAAATGCTATGAGA
AATCTGGCCTGACACCAAATGATATTGACGTAATAGAACTTCACGATTGCTTTTCTACCAACGAACTCCTTACTTATGAAGCACTGGGAC
TCTGTCCAGAAGGACAAGGTGCAACGCTGGTTGATAGAGGAGATAATACATATGGAGGAAAGTGGGTCATAAATCCTAGTGGTGGACTGA
TTTCAAAGGGACACCCACTAGGCGCTACAGGTCTTGCTCAGTGTGCAGAACTCTGCTGGCAGCTGAGAGGGGAAGCCGGAAAGAGGCAAG
TTCCTGGTGCAAAGGTGGCTCTGCAGCATAATTTAGGCATTGGAGGAGCTGTGGTTGTAACACTCTACAAGATGGGTTTTCCGGAAGCCG
CCAGTTCTTTTAGAACTCATCAAATTGAAGCTGTTCCAACCAGCTCTGCAAGTGATGGATTTAAGGCAAATCTTGTTTTTAAGGAGATTG
AGAAGAAACTTGAAGAGGAAGGGGAACAGTTTGTGAAGAAAATCGGTGGTATTTTTGCCTTCAAGGTGAAAGATGGCCCTGGGGGTAAAG
AGGCCACCTGGGTGGTGGATGTGAAGAATGGCAAAGGATCAGTGCTTCCTAACTCAGATAAGAAGGCTGACTGCACAATCACAATGGCTG
ACTCAGACTTCCTGGCTTTAATGACTGGTAAAATGAATCCTCAGTCGGCCTTCTTTCAAGGCAAATTGAAAATCACTGGCAACATGGGTC
TCGCTATGAAGTTACAAAATCTTCAGCTTCAGCCAGGCAACGCTAAGCTCTGAAGAACTCCCTTTGGCTACTTTTGAAAATCAAGATGAG
ATATATAGATATATATCCATACATTTTATTGTCAGAATTTAGACTGAAACTACACATTGGCAAATAGCGTGGGATAGATTTGTTTCTTAA
TGGGTGTGACCAATCCTGTTTTTCCTATGCTCTGGGTGAATAGAGCCTGATGGTATACTACTGCTTTGCGGAATTGCATACAACTGTGCA
TTACAAAGTTAATATGGTAATTATGGTCTGGGGTAAAATTGAGTTTCAGAATAAAATTAGGAACAGTAAAATCCAAAGAACTATGTAAAC
AAAAAAGCTTTTGTTTTGCTTACAAAGTATATTTAAGGATTATTCTGCTGAAGATTCAGTTTAAGAGTTTTCCTTGGGAGAACTAAGTAA
GAAACACAATGCCAACAGCTGGCCAGTAATTAGTGTTGTGCACTTCATGTCATTAATCAATTTCTCAATAGTTCTTAAAATTAGTGAGAT

>19241_19241_4_CPT2-SCP2_CPT2_chr1_53676991_ENST00000371486_SCP2_chr1_53420412_ENST00000407246_length(amino acids)=1014AA_BP=577
MGANGGGGLVFRLQNSPLAAFSPPQAPGTMVPRLLLRAWPRGPAVGPGAPSRPLSAGSGPGQYLQRSIVPTMHYQDSLPRLPIPKLEDTI
RRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDKQNKHTSYISGPWFDMYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTR
ATNMTVSAIRFLKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRLPKPSRDELFTDDKAR
HLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPAPEFPLAYLTSENRDIWAELRQKLMSSGNEESLRKVDSAVFCLCLDDFP
IKDLVHLSHNMLHGDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVFKDSTQTPAVTPQSQPATTDSTVTVQKLNFELTD
ALKTGITAAKEKFDATMKTLTIDCVQFQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASVYTKR
CSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGVAECVLALGFEKMSKGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMF
GYAGKEHMEKYGTKIEHFAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEAFVQKYGLQSKAVE
ILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDIDVIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWV
INPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVPGAKVALQHNLGIGGAVVVTLYKMGFPEAASSFRTHQIEAVPTSSASDGFKA
NLVFKEIEKKLEEEGEQFVKKIGGIFAFKVKDGPGGKEATWVVDVKNGKGSVLPNSDKKADCTITMADSDFLALMTGKMNPQSAFFQGKL

--------------------------------------------------------------
>19241_19241_5_CPT2-SCP2_CPT2_chr1_53676991_ENST00000371486_SCP2_chr1_53420412_ENST00000528311_length(transcript)=3672nt_BP=2160nt
CTCATATCTAGAATTTTGGGAGGTACTTTGAATCATTACGATCTATCTACTTCTTAGGTGAGGAAATAGAGGTTTAAAATTTAGTCCACA
GTCTCGCAAGGATGGAGCCTGGATCAAATTTTGGGTTATCAGATTCCAATCACGTTTCTTAGCTTTTCTTTTTTTTTTCCAACTCCAGTT
TCTGTCTTGCTCCAAAAAAGGGGAAGGAGCGGCTGCGGCGCTCGGTTTCCCGCCTCCTAGGGAAGGGAAGGGAGACGAGCAGCGCGGAGG
CTGGGGCCCCCTTCCGGGCGGGGCCTACTAGTGGGCGGGGCCTGTCAGTGAGCGGCCCCTGCCCGGAAGGAGCCAGTCCGGGGCGGAGCC
GATGGCCTTACAGGGGCCGGAAGTGGCCTGCGGGCGGAGAAGTGCCTCAGGAGTCCTGACGCAGTGTCTTGGGCGCTAACGGCGGCGGCG
GCCTTGTGTTTAGACTCCAGAACTCCCCACTTGCCGCGTTCTCGCCGCCGCAGGCTCCCGGGACGATGGTGCCCCGCCTGCTGCTGCGCG
CCTGGCCCCGGGGCCCCGCGGTTGGTCCGGGAGCCCCCAGTCGGCCCCTCAGCGCCGGCTCCGGGCCCGGCCAGTACCTGCAGCGCAGCA
TCGTGCCCACCATGCACTACCAGGACAGCCTGCCCAGGCTGCCTATTCCCAAACTTGAAGACACCATTAGGAGATACCTCAGTGCACAGA
AGCCTCTCTTGAATGATGGCCAGTTCAGGAAAACAGAACAATTTTGCAAGAGTTTTGAAAATGGGATTGGAAAAGAACTGCATGAGCAGC
TGGTTGCTCTGGACAAACAGAATAAACATACAAGCTACATTTCGGGACCCTGGTTTGATATGTACCTATCTGCTCGAGACTCCGTTGTTC
TGAACTTTAATCCATTTATGGCTTTCAATCCTGACCCAAAATCTGAGTATAATGACCAGCTCACCCGGGCAACCAACATGACTGTTTCTG
CCATCCGGTTTCTGAAGACACTCCGGGCTGGCCTTCTGGAGCCAGAAGTGTTCCACTTGAACCCTGCAAAAAGTGACACTATCACCTTCA
AGAGACTCATACGCTTTGTGCCTTCCTCTCTGTCCTGGTATGGGGCCTACCTGGTCAATGCGTATCCCCTGGATATGTCCCAGTATTTTC
GGCTTTTCAACTCAACTCGTTTACCCAAACCCAGTCGGGATGAACTCTTCACTGATGACAAGGCCAGACACCTCCTGGTCCTAAGGAAAG
GAAATTTTTATATCTTTGATGTCCTGGATCAAGATGGGAACATTGTGAGCCCCTCGGAAATCCAGGCACATCTGAAGTACATTCTCTCAG
ACAGCAGCCCCGCCCCCGAGTTTCCCCTGGCATACCTGACCAGTGAGAACCGAGACATCTGGGCAGAGCTCAGGCAGAAGCTGATGAGTA
GTGGCAATGAGGAGAGCCTGAGGAAAGTGGACTCGGCAGTGTTCTGTCTCTGCCTAGATGACTTCCCCATTAAGGACCTTGTCCACTTGT
CCCACAATATGCTGCATGGGGATGGCACAAACCGCTGGTTTGATAAATCCTTTAACCTCATTATCGCCAAGGATGGCTCTACTGCCGTCC
ACTTTGAGCACTCTTGGGGTGATGGTGTGGCAGTGCTCAGATTTTTTAATGAAGTATTTAAAGACAGCACTCAGACCCCTGCCGTCACTC
CACAGAGCCAGCCAGCTACCACTGACTCTACTGTCACGGTGCAGAAACTCAACTTCGAGCTGACTGATGCCTTAAAGACTGGCATCACAG
CTGCTAAGGAAAAGTTTGATGCCACCATGAAAACCCTCACTATTGACTGCGTCCAGTTTCAGAGAGGAGGCAAAGAATTCCTGAAGAAGC
AAAAGCTGAGCCCTGACGCAGTTGCCCAGCTGGCATTCCAGATGGCCTTCCTGCGGCAGTACGGGCAGACAGTGGCCACCTACGAGTCCT
GTAGCACTGCCGCATTCAAGCACGGCCGCACTGAGACCATCCGCCCGGCCTCCGTCTATACAAAGAGGTGCTCTGAGGCCTTTGTCAGGG
AGCCCTCCAGGCACAGTGCTGGTGAGCTTCAGCAGATGATGGTTGAGTGCTCCAAGTACCATGGCCAGCTGACCAAAGAAGCAGCAATGG
GTGTGGCAGAATGTGTCTTGGCTCTTGGGTTTGAGAAGATGAGTAAGGGAAGCCTTGGAATAAAATTTTCAGATAGAACCATTCCCACTG
ATAAGCATGTTGACCTCCTGATCAATAAGTATGGATTGTCTGCTCACCCAGTTGCTCCTCAGATGTTTGGGTATGCTGGAAAAGAACATA
TGGAAAAATATGGAACAAAAATTGAACACTTTGCAAAAATTGGATGGAAAAATCATAAACATTCAGTTAATAACCCGTATTCCCAGTTCC
AAGATGAATACAGTTTAGATGAAGTGATGGCATCTAAAGAAGTTTTTGATTTTTTGACTATCTTACAATGTTGTCCCACTTCAGATGGTG
CTGCAGCAGCAATTTTGGCCAGTGAAGCATTTGTACAGAAGTATGGCCTGCAATCCAAAGCTGTGGAAATTTTGGCACAAGAAATGATGA
CTGATTTGCCAAGCTCGTTTGAAGAAAAAAGCATTATTAAAATGGTTGGCTTTGATATGAGTAAAGAAGCTGCAAGAAAATGCTATGAGA
AATCTGGCCTGACACCAAATGATATTGACGTAATAGAACTTCACGATTGCTTTTCTACCAACGAACTCCTTACTTATGAAGCACTGGGAC
TCTGTCCAGAAGGACAAGGTGCAACGCTGGTTGATAGAGGAGATAATACATATGGAGGAAAGTGGGTCATAAATCCTAGTGGTGGACTGA
TTTCAAAGGGACACCCACTAGGCGCTACAGGTCTTGCTCAGTGTGCAGAACTCTGCTGGCAGCTGAGAGGGGAAGCCGGAAAGAGGCAAG
TTCCTGGTGCAAAGGTGGCTCTGCAGCATAATTTAGGCATTGGAGGAGCTGTGGTTGTAACACTCTACAAGATGGGTTTTCCGGAAGCCG
CCAGTTCTTTTAGAACTCATCAAATTGAAGCTGTTCCAACCAGCTCTGCAAGTGATGGATTTAAGGCAAATCTTGTTTTTAAGGAGATTG
AGAAGAAACTTGAAGAGGAAGGGGAACAGTTTGTGAAGAAAATCGGTGGTATTTTTGCCTTCAAGGTGAAAGATGGCCCTGGGGGTAAAG
AGGCCACCTGGGTGGTGGATGTGAAGAATGGCAAAGGATCAGTGCTTCCTAACTCAGATAAGAAGGCTGACTGCACAATCACAATGGCTG
ACTCAGACTTCCTGGCTTTAATGACTGGTAAAATGAATCCTCAGTCGGCCTTCTTTCAAGGCAAATTGAAAATCACTGGCAACATGGGTC
TCGCTATGAAGTTACAAAATCTTCAGCTTCAGCCAGGCAACGCTAAGCTCTGAAGAACTCCCTTTGGCTACTTTTGAAAATCAAGATGAG
ATATATAGATATATATCCATACATTTTATTGTCAGAATTTAGACTGAAACTACACATTGGCAAATAGCGTGGGATAGATTTGTTTCTTAA

>19241_19241_5_CPT2-SCP2_CPT2_chr1_53676991_ENST00000371486_SCP2_chr1_53420412_ENST00000528311_length(amino acids)=1014AA_BP=577
MGANGGGGLVFRLQNSPLAAFSPPQAPGTMVPRLLLRAWPRGPAVGPGAPSRPLSAGSGPGQYLQRSIVPTMHYQDSLPRLPIPKLEDTI
RRYLSAQKPLLNDGQFRKTEQFCKSFENGIGKELHEQLVALDKQNKHTSYISGPWFDMYLSARDSVVLNFNPFMAFNPDPKSEYNDQLTR
ATNMTVSAIRFLKTLRAGLLEPEVFHLNPAKSDTITFKRLIRFVPSSLSWYGAYLVNAYPLDMSQYFRLFNSTRLPKPSRDELFTDDKAR
HLLVLRKGNFYIFDVLDQDGNIVSPSEIQAHLKYILSDSSPAPEFPLAYLTSENRDIWAELRQKLMSSGNEESLRKVDSAVFCLCLDDFP
IKDLVHLSHNMLHGDGTNRWFDKSFNLIIAKDGSTAVHFEHSWGDGVAVLRFFNEVFKDSTQTPAVTPQSQPATTDSTVTVQKLNFELTD
ALKTGITAAKEKFDATMKTLTIDCVQFQRGGKEFLKKQKLSPDAVAQLAFQMAFLRQYGQTVATYESCSTAAFKHGRTETIRPASVYTKR
CSEAFVREPSRHSAGELQQMMVECSKYHGQLTKEAAMGVAECVLALGFEKMSKGSLGIKFSDRTIPTDKHVDLLINKYGLSAHPVAPQMF
GYAGKEHMEKYGTKIEHFAKIGWKNHKHSVNNPYSQFQDEYSLDEVMASKEVFDFLTILQCCPTSDGAAAAILASEAFVQKYGLQSKAVE
ILAQEMMTDLPSSFEEKSIIKMVGFDMSKEAARKCYEKSGLTPNDIDVIELHDCFSTNELLTYEALGLCPEGQGATLVDRGDNTYGGKWV
INPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVPGAKVALQHNLGIGGAVVVTLYKMGFPEAASSFRTHQIEAVPTSSASDGFKA
NLVFKEIEKKLEEEGEQFVKKIGGIFAFKVKDGPGGKEATWVVDVKNGKGSVLPNSDKKADCTITMADSDFLALMTGKMNPQSAFFQGKL

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Fusion Gene PPI Analysis for CPT2-SCP2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CPT2-SCP2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CPT2-SCP2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource