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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CREB3L2-MACC1 (FusionGDB2 ID:19327)

Fusion Gene Summary for CREB3L2-MACC1

check button Fusion gene summary
Fusion gene informationFusion gene name: CREB3L2-MACC1
Fusion gene ID: 19327
HgeneTgene
Gene symbol

CREB3L2

MACC1

Gene ID

64764

346389

Gene namecAMP responsive element binding protein 3 like 2MET transcriptional regulator MACC1
SynonymsBBF2H77A5|SH3BP4L
Cytomap

7q33

7p21.1

Type of geneprotein-codingprotein-coding
Descriptioncyclic AMP-responsive element-binding protein 3-like protein 2B-ZIB transcription factorBBF2 human homolog on chromosome 7FUS/BBF2H7 proteinTCAG_1951439basic transcription factor 2cAMP-responsive element-binding protein 3-like protein 2metastasis-associated in colon cancer protein 1MACC1, MET transcriptional regulatorSH3 domain-containing protein 7a5metastasis associated in colon cancer 1putative binding protein 7a5
Modification date2020031320200313
UniProtAcc

Q70SY1

Q6ZN28

Ensembl transtripts involved in fusion geneENST00000330387, ENST00000452463, 
ENST00000456390, ENST00000468127, 
ENST00000458726, 		ENST00000471019, 
ENST00000332878, ENST00000400331, 
ENST00000589011, 
Fusion gene scores* DoF score15 X 16 X 7=16803 X 3 X 3=27
# samples 184
** MAII scorelog2(18/1680*10)=-3.22239242133645
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/27*10)=0.567040592723894
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: CREB3L2 [Title/Abstract] AND MACC1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCREB3L2(137686350)-MACC1(20194004), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCREB3L2

GO:0045893

positive regulation of transcription, DNA-templated

17178827

TgeneMACC1

GO:0045944

positive regulation of transcription by RNA polymerase II

19098908


check buttonFusion gene breakpoints across CREB3L2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across MACC1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-CancerTCGA-BR-6802-11ACREB3L2chr7

137686350

-MACC1chr7

20194004

-


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Fusion Gene ORF analysis for CREB3L2-MACC1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000330387ENST00000471019CREB3L2chr7

137686350

-MACC1chr7

20194004

-
5CDS-intronENST00000452463ENST00000471019CREB3L2chr7

137686350

-MACC1chr7

20194004

-
5CDS-intronENST00000456390ENST00000471019CREB3L2chr7

137686350

-MACC1chr7

20194004

-
5UTR-3CDSENST00000468127ENST00000332878CREB3L2chr7

137686350

-MACC1chr7

20194004

-
5UTR-3CDSENST00000468127ENST00000400331CREB3L2chr7

137686350

-MACC1chr7

20194004

-
5UTR-3CDSENST00000468127ENST00000589011CREB3L2chr7

137686350

-MACC1chr7

20194004

-
5UTR-intronENST00000468127ENST00000471019CREB3L2chr7

137686350

-MACC1chr7

20194004

-
In-frameENST00000330387ENST00000332878CREB3L2chr7

137686350

-MACC1chr7

20194004

-
In-frameENST00000330387ENST00000400331CREB3L2chr7

137686350

-MACC1chr7

20194004

-
In-frameENST00000330387ENST00000589011CREB3L2chr7

137686350

-MACC1chr7

20194004

-
In-frameENST00000452463ENST00000332878CREB3L2chr7

137686350

-MACC1chr7

20194004

-
In-frameENST00000452463ENST00000400331CREB3L2chr7

137686350

-MACC1chr7

20194004

-
In-frameENST00000452463ENST00000589011CREB3L2chr7

137686350

-MACC1chr7

20194004

-
In-frameENST00000456390ENST00000332878CREB3L2chr7

137686350

-MACC1chr7

20194004

-
In-frameENST00000456390ENST00000400331CREB3L2chr7

137686350

-MACC1chr7

20194004

-
In-frameENST00000456390ENST00000589011CREB3L2chr7

137686350

-MACC1chr7

20194004

-
intron-3CDSENST00000458726ENST00000332878CREB3L2chr7

137686350

-MACC1chr7

20194004

-
intron-3CDSENST00000458726ENST00000400331CREB3L2chr7

137686350

-MACC1chr7

20194004

-
intron-3CDSENST00000458726ENST00000589011CREB3L2chr7

137686350

-MACC1chr7

20194004

-
intron-intronENST00000458726ENST00000471019CREB3L2chr7

137686350

-MACC1chr7

20194004

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000330387CREB3L2chr7137686350-ENST00000400331MACC1chr720194004-7147454352855167
ENST00000330387CREB3L2chr7137686350-ENST00000332878MACC1chr720194004-1177454352855167
ENST00000330387CREB3L2chr7137686350-ENST00000589011MACC1chr720194004-885454352855167
ENST00000456390CREB3L2chr7137686350-ENST00000400331MACC1chr720194004-7157464362865167
ENST00000456390CREB3L2chr7137686350-ENST00000332878MACC1chr720194004-1187464362865167
ENST00000456390CREB3L2chr7137686350-ENST00000589011MACC1chr720194004-895464362865167
ENST00000452463CREB3L2chr7137686350-ENST00000400331MACC1chr720194004-7137444342845167
ENST00000452463CREB3L2chr7137686350-ENST00000332878MACC1chr720194004-1167444342845167
ENST00000452463CREB3L2chr7137686350-ENST00000589011MACC1chr720194004-875444342845167

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000330387ENST00000400331CREB3L2chr7137686350-MACC1chr720194004-0.003225770.99677426
ENST00000330387ENST00000332878CREB3L2chr7137686350-MACC1chr720194004-0.0046102150.9953898
ENST00000330387ENST00000589011CREB3L2chr7137686350-MACC1chr720194004-0.0073263730.9926736
ENST00000456390ENST00000400331CREB3L2chr7137686350-MACC1chr720194004-0.0032243960.99677557
ENST00000456390ENST00000332878CREB3L2chr7137686350-MACC1chr720194004-0.0066336080.9933664
ENST00000456390ENST00000589011CREB3L2chr7137686350-MACC1chr720194004-0.0087653650.99123466
ENST00000452463ENST00000400331CREB3L2chr7137686350-MACC1chr720194004-0.0032222370.99677783
ENST00000452463ENST00000332878CREB3L2chr7137686350-MACC1chr720194004-0.0047326550.9952674
ENST00000452463ENST00000589011CREB3L2chr7137686350-MACC1chr720194004-0.0078459640.99215406

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Fusion Genomic Features for CREB3L2-MACC1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CREB3L2-MACC1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:137686350/chr7:20194004)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CREB3L2

Q70SY1

MACC1

Q6ZN28

FUNCTION: Transcription factor involved in unfolded protein response (UPR). In the absence of endoplasmic reticulum (ER) stress, inserted into ER membranes, with N-terminal DNA-binding and transcription activation domains oriented toward the cytosolic face of the membrane. In response to ER stress, transported to the Golgi, where it is cleaved in a site-specific manner by resident proteases S1P/MBTPS1 and S2P/MBTPS2. The released N-terminal cytosolic domain is translocated to the nucleus to effect transcription of specific target genes. Plays a critical role in chondrogenesis by activating the transcription of SEC23A, which promotes the transport and secretion of cartilage matrix proteins, and possibly that of ER biogenesis-related genes (By similarity). In a neuroblastoma cell line, protects cells from ER stress-induced death (PubMed:17178827). In vitro activates transcription of target genes via direct binding to the CRE site (PubMed:17178827). {ECO:0000250|UniProtKB:Q8BH52, ECO:0000269|PubMed:17178827}.FUNCTION: Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo. {ECO:0000269|PubMed:19098908}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000330387-112294_35734521.0DomainbZIP
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000452463-14294_35734249.0DomainbZIP
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000456390-110294_35734461.0DomainbZIP
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000330387-112427_43034521.0MotifS1P recognition
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000452463-14427_43034249.0MotifS1P recognition
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000456390-110427_43034461.0MotifS1P recognition
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000330387-112296_32534521.0RegionBasic motif
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000330387-112336_35734521.0RegionLeucine-zipper
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000452463-14296_32534249.0RegionBasic motif
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000452463-14336_35734249.0RegionLeucine-zipper
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000456390-110296_32534461.0RegionBasic motif
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000456390-110336_35734461.0RegionLeucine-zipper
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000330387-1121_37934521.0Topological domainCytoplasmic
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000330387-112401_52034521.0Topological domainLumenal
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000452463-141_37934249.0Topological domainCytoplasmic
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000452463-14401_52034249.0Topological domainLumenal
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000456390-1101_37934461.0Topological domainCytoplasmic
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000456390-110401_52034461.0Topological domainLumenal
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000330387-112380_40034521.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000452463-14380_40034249.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
HgeneCREB3L2chr7:137686350chr7:20194004ENST00000456390-110380_40034461.0TransmembraneHelical%3B Signal-anchor for type II membrane protein
TgeneMACC1chr7:137686350chr7:20194004ENST0000033287825212_349719853.0DomainZU5
TgeneMACC1chr7:137686350chr7:20194004ENST0000033287825549_619719853.0DomainSH3
TgeneMACC1chr7:137686350chr7:20194004ENST0000040033147212_349719853.0DomainZU5
TgeneMACC1chr7:137686350chr7:20194004ENST0000040033147549_619719853.0DomainSH3
TgeneMACC1chr7:137686350chr7:20194004ENST0000058901125212_349719853.0DomainZU5
TgeneMACC1chr7:137686350chr7:20194004ENST0000058901125549_619719853.0DomainSH3


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Fusion Gene Sequence for CREB3L2-MACC1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>19327_19327_1_CREB3L2-MACC1_CREB3L2_chr7_137686350_ENST00000330387_MACC1_chr7_20194004_ENST00000332878_length(transcript)=1177nt_BP=454nt
GTTTGTGTCTGGAGCCGTAGCGGCAAGTGGGCTTGCGGCTAAGGGATTTTCCTGGGATGAGAGCGGGTCTTCTGCCTTCATTTTGGATGC
ACATCCCGCTTTAGCCCCGGCAGCCTTTGGTCCGGCTCGTGTCCCTGGGGATTCTCGGATCTCCGAGGACACCGGACGGGAGCGCTTGGC
CATCCTCTCTCCGGCAGAGGAGCAGACGTTTGCTTTCCAAGTGCAAAACTACAGACACGCGCGCGCACACACGCAAGCACACGCGGAGAG
AGAGGAACCTTGCCGGTCCGAGGCAGCTCTGCGCGTCCCCTCCTGCGCTTAGCATCCTCGGCCCAGCGCGGCCCGCACCGCCATGGAGGT
GCTGGAGAGCGGGGAGCAGGGCGTGCTGCAGTGGGACCGCAAGCTGAGCGAGCTGTCAGAGCCCGGGGACGGCGAGGCCCTCATGTACCA
CACGGCTCTTCTGAAAATGGATTGCCAAGAGTTAGTCGCACGTCTCATCCAAGAAGCTGCTGTTCTGACTTCAGCTGTCAAGCTTGGAAA
AGGCTGGAGGGAACTAGCTGAAAAGTTAGTACGACTCACAAAGCAACAAATGGAGGCATATGAAATTCCTCATCGAGGAAACACTGGAGA
TGTTGCTGTTGAGATGATGTGGAAACCTGCCTATGATTTTCTGTATACCTGGAGTGCTCACTATGGAAATAACTACAGAGATGTGTTACA
AGACCTTCAGTCAGCTTTGGACAGAATGAAAAACCCTGTGACTAAACACTGGAGAGAATTAACTGGAGTTTTAATACTAGTAAATTCTTT
GGAGGTTTTGAGAGTAACTGCATTCTCCACTTCTGAGGAAGTATAGAAACAAAGCGTGTGTTTTTGATGGGAGGGAAAATGAGGTAATGG
TGTGTGTGTGTGTGTGTCTGTGTGTGTCTGTGTGTGTCTCTGTGTGTCTGTGTGTGTGTGTCTGTGTGTGTGTGTCTGTGTGTGTGTGTG
TGTGTGTGTAGGAAAGAAAGAATCTCAGAAAAGCATTATATTAATTTTCTTCATGCTCAAAACCAGTTTTTTTTTCCTGATGAAAGCACA
GCCTAACTGATAACCAAGATGGGTTTTATCCTCAAATATGTATTTTTGTGTATGTTTCAAATACAAGTATTAGGCTGCTTTGTTCTTAGA

>19327_19327_1_CREB3L2-MACC1_CREB3L2_chr7_137686350_ENST00000330387_MACC1_chr7_20194004_ENST00000332878_length(amino acids)=167AA_BP=34
MEVLESGEQGVLQWDRKLSELSEPGDGEALMYHTALLKMDCQELVARLIQEAAVLTSAVKLGKGWRELAEKLVRLTKQQMEAYEIPHRGN

--------------------------------------------------------------
>19327_19327_2_CREB3L2-MACC1_CREB3L2_chr7_137686350_ENST00000330387_MACC1_chr7_20194004_ENST00000400331_length(transcript)=7147nt_BP=454nt
GTTTGTGTCTGGAGCCGTAGCGGCAAGTGGGCTTGCGGCTAAGGGATTTTCCTGGGATGAGAGCGGGTCTTCTGCCTTCATTTTGGATGC
ACATCCCGCTTTAGCCCCGGCAGCCTTTGGTCCGGCTCGTGTCCCTGGGGATTCTCGGATCTCCGAGGACACCGGACGGGAGCGCTTGGC
CATCCTCTCTCCGGCAGAGGAGCAGACGTTTGCTTTCCAAGTGCAAAACTACAGACACGCGCGCGCACACACGCAAGCACACGCGGAGAG
AGAGGAACCTTGCCGGTCCGAGGCAGCTCTGCGCGTCCCCTCCTGCGCTTAGCATCCTCGGCCCAGCGCGGCCCGCACCGCCATGGAGGT
GCTGGAGAGCGGGGAGCAGGGCGTGCTGCAGTGGGACCGCAAGCTGAGCGAGCTGTCAGAGCCCGGGGACGGCGAGGCCCTCATGTACCA
CACGGCTCTTCTGAAAATGGATTGCCAAGAGTTAGTCGCACGTCTCATCCAAGAAGCTGCTGTTCTGACTTCAGCTGTCAAGCTTGGAAA
AGGCTGGAGGGAACTAGCTGAAAAGTTAGTACGACTCACAAAGCAACAAATGGAGGCATATGAAATTCCTCATCGAGGAAACACTGGAGA
TGTTGCTGTTGAGATGATGTGGAAACCTGCCTATGATTTTCTGTATACCTGGAGTGCTCACTATGGAAATAACTACAGAGATGTGTTACA
AGACCTTCAGTCAGCTTTGGACAGAATGAAAAACCCTGTGACTAAACACTGGAGAGAATTAACTGGAGTTTTAATACTAGTAAATTCTTT
GGAGGTTTTGAGAGTAACTGCATTCTCCACTTCTGAGGAAGTATAGAAACAAAGCGTGTGTTTTTGATGGGAGGGAAAATGAGGTAATGG
TGTGTGTGTGTGTGTGTCTGTGTGTGTCTGTGTGTGTCTCTGTGTGTCTGTGTGTGTGTGTCTGTGTGTGTGTGTCTGTGTGTGTGTGTG
TGTGTGTGTAGGAAAGAAAGAATCTCAGAAAAGCATTATATTAATTTTCTTCATGCTCAAAACCAGTTTTTTTTTCCTGATGAAAGCACA
GCCTAACTGATAACCAAGATGGGTTTTATCCTCAAATATGTATTTTTGTGTATGTTTCAAATACAAGTATTAGGCTGCTTTGTTCTTAGA
AAGGAAAGAAAAAAGAAAAGTGCCCTCTCTCTCTTTCAGTGTTATTTTAAATTTACTAAGTCAAAGCTGTTTGAATAATTACATCACACA
GATATCTGGGTAAACTAGAGACTATCAACATGATCAAGGCAGTGTTCCCAGGAGGCAGCTAGAAAGAGGGGAAGCAAGCACACACCCTGT
GGCCAGTCACGGCTGCCCGCTTTCCACACCTGACCTCTTCAGTTCATCAGTGGGGTTCACCAGCATCACCCCCATTTTTCATGGGGAGAA
ACTCAGAAGTGGAGAGAACGTCTGAGGCTACATAGCCAGTACAAAGTAGGTTTTCTGCTTGAAAAACCTGTTTCTATTTCTTTTTAAAAA
ATCATACTGCATAACAGAATAGTAAAAACAAAATGCGTGTTAAGACTTACAGGGAAACAGTTGCCGTTTCATTTTAAGTGAGACTTGCTA
CTCTTTTTCATCGTCTCTTGAAAGACTGACAGAAGGAAAATATGACTTATCAGAAATCTGTTGTCTGCATGCATGGACCTAGTGTTTTCA
TCAGCTCCCTTCAGCATCTTGGGACCTCTCTAATCCTGCCTAATTTGGGACTTTTTCTGCAGGATTGTAATGTAAAATAGTTCTTTAGCT
CTTGGAGATTTTTAATAATACGAGTTATTAAAAACCACCACCACCAGAAACTTGATTAACTTGATTACCCTGTTGAGTAGAGAGGTCTTA
ACCACCGAAAACACTGATATCTTTATGTTGGCATGCTCATGCAAACACATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTACCA
CAGTGTTTTATAAAGCACAGCCTAATTGATTATATAGGACAAAAATTGTATAGGACCCTGGGTCAGTATAAATGCTAATGGCTGACAAAG
TTCACAAAGAGATGTATTTTGCTTACTCCTCTGTTCAATCCTCTGGTTGCCTGCCAGTGTTTATGTGTGTATTTGGACAGACATTCATTT
ATTGTCATTCAGTCAATAGGTAGAGTATATGTGTCTATTTTTTGGCAGGCATATAGATGCTTGAGGCTAATGGGAAAAAACCAGCATGAA
CTCTGACTTTAGTAGTGCTAAGTAATAGATAATTTTAAAAAATGACACCGTTAAATAGAAAATGGCATGCATACTAACAGTTGCAATGGA
GAGGCTGTGATGCTACGAGATATAAACGTAGAGATGCCATCATGTGAAACTGGAAGTGGGGGTGGGTCAGGGAAATTTGTTCTTGGAAAG
AAATAATGAACCTCAAGGAAGAGTAGGCATTGTCCTGGTGTGGTGGGGTGTAAGCGGTGATCCCACAAAGCACTGAAGCTCTTAGATGGG
TGGGAGCTGAATAGGTGCAGATAGCAGGGGTGAAGGAGTGAAAGGATAAAAGATTCAAGGTTGAGATGAGGATGGAGCAAGAAGAAGCCA
CATTAGGGCCATTAAGGCTGCTAGAATTTAGAAAGAAAACACACAGCCTCAAAGAAATGTGGGTAAGCCAAAGAAGGATTTTGTTTTGGG
AACCTGAATAAAAGATGTCCATTTGGCTAAAAAGTAAAAGCAGAATCTTTTTAGGGCTTTTAATATACCCACCCTGGGATATTTGGTATG
CTGGCAATGGTAATTCAAATTGGCGTTTAAGAATAATCTTGGCCGGGCGCGATGGCTCATGCCTGAAATCCCAGCACTTTGGGAGGCCGA
GGCGGGCAGATCACTAGGTCAGGAGATCGAGACCATCCTGGCTAACGCGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGG
GCGTGGTGGCAGGCGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCC
GAGTTCATGCCACTGCACTCCAGCCTGGGTGACAGGCTGTCTCAAAAAAAAAAAAAGGAATAATCTGTACGGCTTTCAGTATTTATATTT
GATTATAAGGGAACACAGCCTGACCAAATAATTATGTATACACATTCAAGGACAGAATTTATTTTAATTAAAAATAAATTATGAGAGAAG
GAAAAAAAAGCACAGTTTTTACTTTCAGAACACAGTCCTTTTTTGTGGTGATTTTGCTTTCTTTAGAACATTCTTGGAATCTTATTAACA
TGTCAGCTAACCAGAGAATTTTGGGAAGGGATAGTGGGGATTAATAACTGGGTTTTTCCAGGCTCCAAGATCTAAGAAGACAGAGATCTT
GTTAGCTGATTAGTGTAGTAAGATTAAATAAATAATTTAAGGTTTACATTGCATCATGTATTATGATTGTGATTGAGAATAATAAGAGTT
TAAAAAAATGAAAAACAAGATCTCTGTAATTTGAGGATGAAACAATGGTTCTAATATTAATACACACAAATATATTTTATAATCTTGTAA
CAAATCCTTCCAGGGGAAATTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGCCAGAGTCTGGCTCTGTTGCCCAGACTGGAGTGCGGTG
TTTCAATCTTGACTCACTGCAACCTCCACCTCCTGGGTTCAAAAGATCCTTCTGCCTCCGCCTCCCAAGTAGCTGGGATTACAGGCATGC
ACCACCTTGTCCGGGTAATTTTTGTATTTTTAGTGGAGACAAGGTTTTACCATTTTGGCCAGACTGGTCTGGAACTCCTGACCTCAGGTC
ATCCACCTGCCTCGGCCTCCCAGAGTGCTAGGATTACAGGCATGAGCCACTGCTCCCAGCCTTCCAGAGGAATTTTAAGCCCATGTCCAA
ACATTCTGTTTGTATAAATATATTCTAATTTTTAAATAAATAGTTTCTACTTTTCTGAACTTTATATTTTTTCTTGCTATAATGGATTTT
CATAATCAGAAAAGATTAAATTAGTAATCATGAATTGCCTTCAATATTTGGCAGTAAGTCAATGAAATAATAAGGCACTTATATACCATC
TTTGACATCATTAAAAGTATCAAATCCCATTAATCTAAAACTTCTTTAAGCATTTTGAAAGCAGAAAATGTTTACATGGTTCTTTCAGTT
CCTCAGGCTTTTTGTCTAATGATGCGTGACTTAGGATAAGATTTGAATTAAGTGCCCAGCTTGAAACATAATAATTTTTCTGTATAAGCC
ACAGATCCTCTACCTCCTTTGTGTTAAAGCCTTTATATGAAACAATTAAGTAGAAGCATTCAATAGTGTGTCATTAACTGTTCATACTAA
TAAATGGATACAGCACATTTTCATGGCCTGTAATGTAGAACATACTATATAAAGTTCTCAGTTTGGGGATGACTAGGTTTCTGGAAGGAA
TAGAATGCTAAATCAATGGATGGCATTGGGCTGAGAAACACTGCTGCTACTAATCAGCCTTGAATGTGTAATGTGAACATGCAAAAGAGA
ACATGCATACACTCAAATTTGTACAATGCTATAACTGGAAGTTGAAGGACTTGAATTTTTATATTGTGCTATTGTTATGTTTTCTGTAAT
TGTTTATATCTAAGGAATTTTTGAGGTAATATAAAAGAAAAAGAGAATAATGAACAATGATGTCACTGGAGGGTTTTTACATTAAATTAG
ATCATTTTTCTTCTTATTCACAATAATAATCTTAATCTTTAAGAATTAATTATAATTTAATATTATAATTCATAATCTTTAAGAATTAAT
AATTATAATTTAATATTATAATTAATAATCTTTAAGAATTAATAATATAATTTAATATTATAATTAATAATCTTTAAGAATTAATAATTA
CAATTAATAATTAATAATAATCTTAATCTTTAAGAATTAATAATAATCCTTAATCGCAATAATAATCGCAAGGAGGAGAAGTAAGTCCCT
CCTCCTTCTGTATGAACTTTTCTCCCACATGCTGCTGTATGGTTTAGTGAGAGTGAAGTTCTAAAGAACATCAATATGATTGGTGGGATA
ATCCAAAGACATTTTTTCAGAATCAAATGGCATGTCGAAGGTTTGTTTCTTGCATATGTATTTACTGGTCCACAGCACAAAATAAAGTGA
CCACATATACATAGGAAAGTTGAATTTGTACACATACAGCATCTGAAATGTATCTGATGTTCAGCATCAAGATTTCACTGAACATTGTAG
AAATGTGTATCTTTTGCATGTATATTTTACATTGATTTTCTATTTATGTACATCTAGAAAGTTTTAACCCTAATAAATAGTTTTGTAATT
TTGAATAATAGTGTCAGTTTATATGTGAGGGAGTAGAGACAGAGAGGTTAGCACTGGATAATAATTAGTAAGGCCAAAGGAGAAAATTTC
ATAGAAAATATTGTTGTTGTCATAATGAGTACAGCATGAAAGGCTTCCTCTACAAGACACTAGTCAAAGAGTTGAGAGCTGCGGTTTCTA
ATCTTTGTCCATTACTCCCTTACTCCCTATGAGACTGTGGACCTGTCACTTGGCCTCTCTGGTCTTCAGTTTTCTCACCAGTAAAACAAG
GAACTTGAACCAAATGACCTCTAGTGTTCCCCTTGGGTTTAAATGTCTATAAATGTTCAATGACTAGAATGTATTGCGTTTTTCTTTATT
CTTTTTGCTTTGAGAAAAGAGAATGTGATTTAAGAGTAATAATTTGAATACCAATTATCCACATTAAAATTGTGTCCTCTATGTGTAAGG
CATAGCACATTTAGCACACATACATAAGCACACTAAGCACCTTACAAATATCCTCATTTATTCTTTACATAATCTTTTGAAATTGATTAT
GTAATACACACTGTTTTTGAACAATTGGTGACTTCCAGCTGTTTAAAACAAACTACAGTATGGTGCTTGAGTACTGACTTAGGAGGTCAG
CATTGGTTTCACTAGGAGCTTCTCAAAGCACGCTGCCAAACATGCTCCAGTCTCATTGTCAAGGCCTTAGACCAGGCAATCATTACGGCA
GTGGTTCTTCAACTTCAGCAGCAGCAAAACGATCTGGCGGGGGCTTGGTGAAACAGACTGCTGGGCTCGACCACCAGAATTTCTCATTCA
GAGGGTCTGGCCTGATCACTTGCATTTCTAATCACTTCCCAGGTGATGCAGATGTTTCTGGTCCAGGGACCCCAGTTTGAGAACCACTGT
ATTAAAATTTCCTTCATCTCTATAGAAATGGAAAGATTTTTTATAAGTCCTCTAATTTGCTTTAAGATAAATGAGATTTCACTTAATTCT
GTTGGAGAAATTGTTTTAAAAATTGTGCTAAAGAACCGAAAATCACTTTATGTTAAGGCTCTATTTATAGCAAGTGAACTTTTCATGAGT
TAATAAAGGCCTACAAAAATAATTTTGACTGTGAAACTAATTAAAATCTCTGTGTTTCATTTAAAGCATAAACATATTTGAATAAAAATA
GGTTAACAATAATTTGGGACATGTATTCAGTATAATTTTAAGATAATTTTACAAAATATATGTAACATTGCATTTGTTTCTGTAAAATAT
CTTCGGAAAAAGCCTTGTTTTCCCTAGTGTGTTATTTGTTGAATTTCTTGTTAAATGTATTTTTTCCCATTGAAAAAAATGTTTTTAATC
AATGTGATCAATACAGCTATCTATATGCCCTGCTTTCACTGTAGAATTAGAAAGTGTTAATAAGGTGATCGGATGTTCTTTCTAAGGATC
ATATTCCACATTTAAAGAGATGGTGACTGAGAAGAGGTGGCAAGCTGAACCATCTCACTTTGAGATTGACGTATCACGTTTTATCCTCTG
CCATCATTTCCTTGTTAATTGTTTTTCTTTGGGTGATTGGAAGAATCTATGGCTTCCTTTTCTCTGTTCTTAAAGATATCAAGACTCTGC
CCTTTTGTGACTGGAAGTAGATTTTAAATGTCCCTAATGTTTATATGCTCACTTAAACTCAATACATGGAATTTACTGGGGCATTTAACT

>19327_19327_2_CREB3L2-MACC1_CREB3L2_chr7_137686350_ENST00000330387_MACC1_chr7_20194004_ENST00000400331_length(amino acids)=167AA_BP=34
MEVLESGEQGVLQWDRKLSELSEPGDGEALMYHTALLKMDCQELVARLIQEAAVLTSAVKLGKGWRELAEKLVRLTKQQMEAYEIPHRGN

--------------------------------------------------------------
>19327_19327_3_CREB3L2-MACC1_CREB3L2_chr7_137686350_ENST00000330387_MACC1_chr7_20194004_ENST00000589011_length(transcript)=885nt_BP=454nt
GTTTGTGTCTGGAGCCGTAGCGGCAAGTGGGCTTGCGGCTAAGGGATTTTCCTGGGATGAGAGCGGGTCTTCTGCCTTCATTTTGGATGC
ACATCCCGCTTTAGCCCCGGCAGCCTTTGGTCCGGCTCGTGTCCCTGGGGATTCTCGGATCTCCGAGGACACCGGACGGGAGCGCTTGGC
CATCCTCTCTCCGGCAGAGGAGCAGACGTTTGCTTTCCAAGTGCAAAACTACAGACACGCGCGCGCACACACGCAAGCACACGCGGAGAG
AGAGGAACCTTGCCGGTCCGAGGCAGCTCTGCGCGTCCCCTCCTGCGCTTAGCATCCTCGGCCCAGCGCGGCCCGCACCGCCATGGAGGT
GCTGGAGAGCGGGGAGCAGGGCGTGCTGCAGTGGGACCGCAAGCTGAGCGAGCTGTCAGAGCCCGGGGACGGCGAGGCCCTCATGTACCA
CACGGCTCTTCTGAAAATGGATTGCCAAGAGTTAGTCGCACGTCTCATCCAAGAAGCTGCTGTTCTGACTTCAGCTGTCAAGCTTGGAAA
AGGCTGGAGGGAACTAGCTGAAAAGTTAGTACGACTCACAAAGCAACAAATGGAGGCATATGAAATTCCTCATCGAGGAAACACTGGAGA
TGTTGCTGTTGAGATGATGTGGAAACCTGCCTATGATTTTCTGTATACCTGGAGTGCTCACTATGGAAATAACTACAGAGATGTGTTACA
AGACCTTCAGTCAGCTTTGGACAGAATGAAAAACCCTGTGACTAAACACTGGAGAGAATTAACTGGAGTTTTAATACTAGTAAATTCTTT

>19327_19327_3_CREB3L2-MACC1_CREB3L2_chr7_137686350_ENST00000330387_MACC1_chr7_20194004_ENST00000589011_length(amino acids)=167AA_BP=34
MEVLESGEQGVLQWDRKLSELSEPGDGEALMYHTALLKMDCQELVARLIQEAAVLTSAVKLGKGWRELAEKLVRLTKQQMEAYEIPHRGN

--------------------------------------------------------------
>19327_19327_4_CREB3L2-MACC1_CREB3L2_chr7_137686350_ENST00000452463_MACC1_chr7_20194004_ENST00000332878_length(transcript)=1167nt_BP=444nt
GGAGCCGTAGCGGCAAGTGGGCTTGCGGCTAAGGGATTTTCCTGGGATGAGAGCGGGTCTTCTGCCTTCATTTTGGATGCACATCCCGCT
TTAGCCCCGGCAGCCTTTGGTCCGGCTCGTGTCCCTGGGGATTCTCGGATCTCCGAGGACACCGGACGGGAGCGCTTGGCCATCCTCTCT
CCGGCAGAGGAGCAGACGTTTGCTTTCCAAGTGCAAAACTACAGACACGCGCGCGCACACACGCAAGCACACGCGGAGAGAGAGGAACCT
TGCCGGTCCGAGGCAGCTCTGCGCGTCCCCTCCTGCGCTTAGCATCCTCGGCCCAGCGCGGCCCGCACCGCCATGGAGGTGCTGGAGAGC
GGGGAGCAGGGCGTGCTGCAGTGGGACCGCAAGCTGAGCGAGCTGTCAGAGCCCGGGGACGGCGAGGCCCTCATGTACCACACGGCTCTT
CTGAAAATGGATTGCCAAGAGTTAGTCGCACGTCTCATCCAAGAAGCTGCTGTTCTGACTTCAGCTGTCAAGCTTGGAAAAGGCTGGAGG
GAACTAGCTGAAAAGTTAGTACGACTCACAAAGCAACAAATGGAGGCATATGAAATTCCTCATCGAGGAAACACTGGAGATGTTGCTGTT
GAGATGATGTGGAAACCTGCCTATGATTTTCTGTATACCTGGAGTGCTCACTATGGAAATAACTACAGAGATGTGTTACAAGACCTTCAG
TCAGCTTTGGACAGAATGAAAAACCCTGTGACTAAACACTGGAGAGAATTAACTGGAGTTTTAATACTAGTAAATTCTTTGGAGGTTTTG
AGAGTAACTGCATTCTCCACTTCTGAGGAAGTATAGAAACAAAGCGTGTGTTTTTGATGGGAGGGAAAATGAGGTAATGGTGTGTGTGTG
TGTGTGTCTGTGTGTGTCTGTGTGTGTCTCTGTGTGTCTGTGTGTGTGTGTCTGTGTGTGTGTGTCTGTGTGTGTGTGTGTGTGTGTGTA
GGAAAGAAAGAATCTCAGAAAAGCATTATATTAATTTTCTTCATGCTCAAAACCAGTTTTTTTTTCCTGATGAAAGCACAGCCTAACTGA

>19327_19327_4_CREB3L2-MACC1_CREB3L2_chr7_137686350_ENST00000452463_MACC1_chr7_20194004_ENST00000332878_length(amino acids)=167AA_BP=34
MEVLESGEQGVLQWDRKLSELSEPGDGEALMYHTALLKMDCQELVARLIQEAAVLTSAVKLGKGWRELAEKLVRLTKQQMEAYEIPHRGN

--------------------------------------------------------------
>19327_19327_5_CREB3L2-MACC1_CREB3L2_chr7_137686350_ENST00000452463_MACC1_chr7_20194004_ENST00000400331_length(transcript)=7137nt_BP=444nt
GGAGCCGTAGCGGCAAGTGGGCTTGCGGCTAAGGGATTTTCCTGGGATGAGAGCGGGTCTTCTGCCTTCATTTTGGATGCACATCCCGCT
TTAGCCCCGGCAGCCTTTGGTCCGGCTCGTGTCCCTGGGGATTCTCGGATCTCCGAGGACACCGGACGGGAGCGCTTGGCCATCCTCTCT
CCGGCAGAGGAGCAGACGTTTGCTTTCCAAGTGCAAAACTACAGACACGCGCGCGCACACACGCAAGCACACGCGGAGAGAGAGGAACCT
TGCCGGTCCGAGGCAGCTCTGCGCGTCCCCTCCTGCGCTTAGCATCCTCGGCCCAGCGCGGCCCGCACCGCCATGGAGGTGCTGGAGAGC
GGGGAGCAGGGCGTGCTGCAGTGGGACCGCAAGCTGAGCGAGCTGTCAGAGCCCGGGGACGGCGAGGCCCTCATGTACCACACGGCTCTT
CTGAAAATGGATTGCCAAGAGTTAGTCGCACGTCTCATCCAAGAAGCTGCTGTTCTGACTTCAGCTGTCAAGCTTGGAAAAGGCTGGAGG
GAACTAGCTGAAAAGTTAGTACGACTCACAAAGCAACAAATGGAGGCATATGAAATTCCTCATCGAGGAAACACTGGAGATGTTGCTGTT
GAGATGATGTGGAAACCTGCCTATGATTTTCTGTATACCTGGAGTGCTCACTATGGAAATAACTACAGAGATGTGTTACAAGACCTTCAG
TCAGCTTTGGACAGAATGAAAAACCCTGTGACTAAACACTGGAGAGAATTAACTGGAGTTTTAATACTAGTAAATTCTTTGGAGGTTTTG
AGAGTAACTGCATTCTCCACTTCTGAGGAAGTATAGAAACAAAGCGTGTGTTTTTGATGGGAGGGAAAATGAGGTAATGGTGTGTGTGTG
TGTGTGTCTGTGTGTGTCTGTGTGTGTCTCTGTGTGTCTGTGTGTGTGTGTCTGTGTGTGTGTGTCTGTGTGTGTGTGTGTGTGTGTGTA
GGAAAGAAAGAATCTCAGAAAAGCATTATATTAATTTTCTTCATGCTCAAAACCAGTTTTTTTTTCCTGATGAAAGCACAGCCTAACTGA
TAACCAAGATGGGTTTTATCCTCAAATATGTATTTTTGTGTATGTTTCAAATACAAGTATTAGGCTGCTTTGTTCTTAGAAAGGAAAGAA
AAAAGAAAAGTGCCCTCTCTCTCTTTCAGTGTTATTTTAAATTTACTAAGTCAAAGCTGTTTGAATAATTACATCACACAGATATCTGGG
TAAACTAGAGACTATCAACATGATCAAGGCAGTGTTCCCAGGAGGCAGCTAGAAAGAGGGGAAGCAAGCACACACCCTGTGGCCAGTCAC
GGCTGCCCGCTTTCCACACCTGACCTCTTCAGTTCATCAGTGGGGTTCACCAGCATCACCCCCATTTTTCATGGGGAGAAACTCAGAAGT
GGAGAGAACGTCTGAGGCTACATAGCCAGTACAAAGTAGGTTTTCTGCTTGAAAAACCTGTTTCTATTTCTTTTTAAAAAATCATACTGC
ATAACAGAATAGTAAAAACAAAATGCGTGTTAAGACTTACAGGGAAACAGTTGCCGTTTCATTTTAAGTGAGACTTGCTACTCTTTTTCA
TCGTCTCTTGAAAGACTGACAGAAGGAAAATATGACTTATCAGAAATCTGTTGTCTGCATGCATGGACCTAGTGTTTTCATCAGCTCCCT
TCAGCATCTTGGGACCTCTCTAATCCTGCCTAATTTGGGACTTTTTCTGCAGGATTGTAATGTAAAATAGTTCTTTAGCTCTTGGAGATT
TTTAATAATACGAGTTATTAAAAACCACCACCACCAGAAACTTGATTAACTTGATTACCCTGTTGAGTAGAGAGGTCTTAACCACCGAAA
ACACTGATATCTTTATGTTGGCATGCTCATGCAAACACATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTACCACAGTGTTTTA
TAAAGCACAGCCTAATTGATTATATAGGACAAAAATTGTATAGGACCCTGGGTCAGTATAAATGCTAATGGCTGACAAAGTTCACAAAGA
GATGTATTTTGCTTACTCCTCTGTTCAATCCTCTGGTTGCCTGCCAGTGTTTATGTGTGTATTTGGACAGACATTCATTTATTGTCATTC
AGTCAATAGGTAGAGTATATGTGTCTATTTTTTGGCAGGCATATAGATGCTTGAGGCTAATGGGAAAAAACCAGCATGAACTCTGACTTT
AGTAGTGCTAAGTAATAGATAATTTTAAAAAATGACACCGTTAAATAGAAAATGGCATGCATACTAACAGTTGCAATGGAGAGGCTGTGA
TGCTACGAGATATAAACGTAGAGATGCCATCATGTGAAACTGGAAGTGGGGGTGGGTCAGGGAAATTTGTTCTTGGAAAGAAATAATGAA
CCTCAAGGAAGAGTAGGCATTGTCCTGGTGTGGTGGGGTGTAAGCGGTGATCCCACAAAGCACTGAAGCTCTTAGATGGGTGGGAGCTGA
ATAGGTGCAGATAGCAGGGGTGAAGGAGTGAAAGGATAAAAGATTCAAGGTTGAGATGAGGATGGAGCAAGAAGAAGCCACATTAGGGCC
ATTAAGGCTGCTAGAATTTAGAAAGAAAACACACAGCCTCAAAGAAATGTGGGTAAGCCAAAGAAGGATTTTGTTTTGGGAACCTGAATA
AAAGATGTCCATTTGGCTAAAAAGTAAAAGCAGAATCTTTTTAGGGCTTTTAATATACCCACCCTGGGATATTTGGTATGCTGGCAATGG
TAATTCAAATTGGCGTTTAAGAATAATCTTGGCCGGGCGCGATGGCTCATGCCTGAAATCCCAGCACTTTGGGAGGCCGAGGCGGGCAGA
TCACTAGGTCAGGAGATCGAGACCATCCTGGCTAACGCGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCGTGGTGGC
AGGCGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGTTCATGC
CACTGCACTCCAGCCTGGGTGACAGGCTGTCTCAAAAAAAAAAAAAGGAATAATCTGTACGGCTTTCAGTATTTATATTTGATTATAAGG
GAACACAGCCTGACCAAATAATTATGTATACACATTCAAGGACAGAATTTATTTTAATTAAAAATAAATTATGAGAGAAGGAAAAAAAAG
CACAGTTTTTACTTTCAGAACACAGTCCTTTTTTGTGGTGATTTTGCTTTCTTTAGAACATTCTTGGAATCTTATTAACATGTCAGCTAA
CCAGAGAATTTTGGGAAGGGATAGTGGGGATTAATAACTGGGTTTTTCCAGGCTCCAAGATCTAAGAAGACAGAGATCTTGTTAGCTGAT
TAGTGTAGTAAGATTAAATAAATAATTTAAGGTTTACATTGCATCATGTATTATGATTGTGATTGAGAATAATAAGAGTTTAAAAAAATG
AAAAACAAGATCTCTGTAATTTGAGGATGAAACAATGGTTCTAATATTAATACACACAAATATATTTTATAATCTTGTAACAAATCCTTC
CAGGGGAAATTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGCCAGAGTCTGGCTCTGTTGCCCAGACTGGAGTGCGGTGTTTCAATCTT
GACTCACTGCAACCTCCACCTCCTGGGTTCAAAAGATCCTTCTGCCTCCGCCTCCCAAGTAGCTGGGATTACAGGCATGCACCACCTTGT
CCGGGTAATTTTTGTATTTTTAGTGGAGACAAGGTTTTACCATTTTGGCCAGACTGGTCTGGAACTCCTGACCTCAGGTCATCCACCTGC
CTCGGCCTCCCAGAGTGCTAGGATTACAGGCATGAGCCACTGCTCCCAGCCTTCCAGAGGAATTTTAAGCCCATGTCCAAACATTCTGTT
TGTATAAATATATTCTAATTTTTAAATAAATAGTTTCTACTTTTCTGAACTTTATATTTTTTCTTGCTATAATGGATTTTCATAATCAGA
AAAGATTAAATTAGTAATCATGAATTGCCTTCAATATTTGGCAGTAAGTCAATGAAATAATAAGGCACTTATATACCATCTTTGACATCA
TTAAAAGTATCAAATCCCATTAATCTAAAACTTCTTTAAGCATTTTGAAAGCAGAAAATGTTTACATGGTTCTTTCAGTTCCTCAGGCTT
TTTGTCTAATGATGCGTGACTTAGGATAAGATTTGAATTAAGTGCCCAGCTTGAAACATAATAATTTTTCTGTATAAGCCACAGATCCTC
TACCTCCTTTGTGTTAAAGCCTTTATATGAAACAATTAAGTAGAAGCATTCAATAGTGTGTCATTAACTGTTCATACTAATAAATGGATA
CAGCACATTTTCATGGCCTGTAATGTAGAACATACTATATAAAGTTCTCAGTTTGGGGATGACTAGGTTTCTGGAAGGAATAGAATGCTA
AATCAATGGATGGCATTGGGCTGAGAAACACTGCTGCTACTAATCAGCCTTGAATGTGTAATGTGAACATGCAAAAGAGAACATGCATAC
ACTCAAATTTGTACAATGCTATAACTGGAAGTTGAAGGACTTGAATTTTTATATTGTGCTATTGTTATGTTTTCTGTAATTGTTTATATC
TAAGGAATTTTTGAGGTAATATAAAAGAAAAAGAGAATAATGAACAATGATGTCACTGGAGGGTTTTTACATTAAATTAGATCATTTTTC
TTCTTATTCACAATAATAATCTTAATCTTTAAGAATTAATTATAATTTAATATTATAATTCATAATCTTTAAGAATTAATAATTATAATT
TAATATTATAATTAATAATCTTTAAGAATTAATAATATAATTTAATATTATAATTAATAATCTTTAAGAATTAATAATTACAATTAATAA
TTAATAATAATCTTAATCTTTAAGAATTAATAATAATCCTTAATCGCAATAATAATCGCAAGGAGGAGAAGTAAGTCCCTCCTCCTTCTG
TATGAACTTTTCTCCCACATGCTGCTGTATGGTTTAGTGAGAGTGAAGTTCTAAAGAACATCAATATGATTGGTGGGATAATCCAAAGAC
ATTTTTTCAGAATCAAATGGCATGTCGAAGGTTTGTTTCTTGCATATGTATTTACTGGTCCACAGCACAAAATAAAGTGACCACATATAC
ATAGGAAAGTTGAATTTGTACACATACAGCATCTGAAATGTATCTGATGTTCAGCATCAAGATTTCACTGAACATTGTAGAAATGTGTAT
CTTTTGCATGTATATTTTACATTGATTTTCTATTTATGTACATCTAGAAAGTTTTAACCCTAATAAATAGTTTTGTAATTTTGAATAATA
GTGTCAGTTTATATGTGAGGGAGTAGAGACAGAGAGGTTAGCACTGGATAATAATTAGTAAGGCCAAAGGAGAAAATTTCATAGAAAATA
TTGTTGTTGTCATAATGAGTACAGCATGAAAGGCTTCCTCTACAAGACACTAGTCAAAGAGTTGAGAGCTGCGGTTTCTAATCTTTGTCC
ATTACTCCCTTACTCCCTATGAGACTGTGGACCTGTCACTTGGCCTCTCTGGTCTTCAGTTTTCTCACCAGTAAAACAAGGAACTTGAAC
CAAATGACCTCTAGTGTTCCCCTTGGGTTTAAATGTCTATAAATGTTCAATGACTAGAATGTATTGCGTTTTTCTTTATTCTTTTTGCTT
TGAGAAAAGAGAATGTGATTTAAGAGTAATAATTTGAATACCAATTATCCACATTAAAATTGTGTCCTCTATGTGTAAGGCATAGCACAT
TTAGCACACATACATAAGCACACTAAGCACCTTACAAATATCCTCATTTATTCTTTACATAATCTTTTGAAATTGATTATGTAATACACA
CTGTTTTTGAACAATTGGTGACTTCCAGCTGTTTAAAACAAACTACAGTATGGTGCTTGAGTACTGACTTAGGAGGTCAGCATTGGTTTC
ACTAGGAGCTTCTCAAAGCACGCTGCCAAACATGCTCCAGTCTCATTGTCAAGGCCTTAGACCAGGCAATCATTACGGCAGTGGTTCTTC
AACTTCAGCAGCAGCAAAACGATCTGGCGGGGGCTTGGTGAAACAGACTGCTGGGCTCGACCACCAGAATTTCTCATTCAGAGGGTCTGG
CCTGATCACTTGCATTTCTAATCACTTCCCAGGTGATGCAGATGTTTCTGGTCCAGGGACCCCAGTTTGAGAACCACTGTATTAAAATTT
CCTTCATCTCTATAGAAATGGAAAGATTTTTTATAAGTCCTCTAATTTGCTTTAAGATAAATGAGATTTCACTTAATTCTGTTGGAGAAA
TTGTTTTAAAAATTGTGCTAAAGAACCGAAAATCACTTTATGTTAAGGCTCTATTTATAGCAAGTGAACTTTTCATGAGTTAATAAAGGC
CTACAAAAATAATTTTGACTGTGAAACTAATTAAAATCTCTGTGTTTCATTTAAAGCATAAACATATTTGAATAAAAATAGGTTAACAAT
AATTTGGGACATGTATTCAGTATAATTTTAAGATAATTTTACAAAATATATGTAACATTGCATTTGTTTCTGTAAAATATCTTCGGAAAA
AGCCTTGTTTTCCCTAGTGTGTTATTTGTTGAATTTCTTGTTAAATGTATTTTTTCCCATTGAAAAAAATGTTTTTAATCAATGTGATCA
ATACAGCTATCTATATGCCCTGCTTTCACTGTAGAATTAGAAAGTGTTAATAAGGTGATCGGATGTTCTTTCTAAGGATCATATTCCACA
TTTAAAGAGATGGTGACTGAGAAGAGGTGGCAAGCTGAACCATCTCACTTTGAGATTGACGTATCACGTTTTATCCTCTGCCATCATTTC
CTTGTTAATTGTTTTTCTTTGGGTGATTGGAAGAATCTATGGCTTCCTTTTCTCTGTTCTTAAAGATATCAAGACTCTGCCCTTTTGTGA
CTGGAAGTAGATTTTAAATGTCCCTAATGTTTATATGCTCACTTAAACTCAATACATGGAATTTACTGGGGCATTTAACTTGTTCATGAA

>19327_19327_5_CREB3L2-MACC1_CREB3L2_chr7_137686350_ENST00000452463_MACC1_chr7_20194004_ENST00000400331_length(amino acids)=167AA_BP=34
MEVLESGEQGVLQWDRKLSELSEPGDGEALMYHTALLKMDCQELVARLIQEAAVLTSAVKLGKGWRELAEKLVRLTKQQMEAYEIPHRGN

--------------------------------------------------------------
>19327_19327_6_CREB3L2-MACC1_CREB3L2_chr7_137686350_ENST00000452463_MACC1_chr7_20194004_ENST00000589011_length(transcript)=875nt_BP=444nt
GGAGCCGTAGCGGCAAGTGGGCTTGCGGCTAAGGGATTTTCCTGGGATGAGAGCGGGTCTTCTGCCTTCATTTTGGATGCACATCCCGCT
TTAGCCCCGGCAGCCTTTGGTCCGGCTCGTGTCCCTGGGGATTCTCGGATCTCCGAGGACACCGGACGGGAGCGCTTGGCCATCCTCTCT
CCGGCAGAGGAGCAGACGTTTGCTTTCCAAGTGCAAAACTACAGACACGCGCGCGCACACACGCAAGCACACGCGGAGAGAGAGGAACCT
TGCCGGTCCGAGGCAGCTCTGCGCGTCCCCTCCTGCGCTTAGCATCCTCGGCCCAGCGCGGCCCGCACCGCCATGGAGGTGCTGGAGAGC
GGGGAGCAGGGCGTGCTGCAGTGGGACCGCAAGCTGAGCGAGCTGTCAGAGCCCGGGGACGGCGAGGCCCTCATGTACCACACGGCTCTT
CTGAAAATGGATTGCCAAGAGTTAGTCGCACGTCTCATCCAAGAAGCTGCTGTTCTGACTTCAGCTGTCAAGCTTGGAAAAGGCTGGAGG
GAACTAGCTGAAAAGTTAGTACGACTCACAAAGCAACAAATGGAGGCATATGAAATTCCTCATCGAGGAAACACTGGAGATGTTGCTGTT
GAGATGATGTGGAAACCTGCCTATGATTTTCTGTATACCTGGAGTGCTCACTATGGAAATAACTACAGAGATGTGTTACAAGACCTTCAG
TCAGCTTTGGACAGAATGAAAAACCCTGTGACTAAACACTGGAGAGAATTAACTGGAGTTTTAATACTAGTAAATTCTTTGGAGGTTTTG

>19327_19327_6_CREB3L2-MACC1_CREB3L2_chr7_137686350_ENST00000452463_MACC1_chr7_20194004_ENST00000589011_length(amino acids)=167AA_BP=34
MEVLESGEQGVLQWDRKLSELSEPGDGEALMYHTALLKMDCQELVARLIQEAAVLTSAVKLGKGWRELAEKLVRLTKQQMEAYEIPHRGN

--------------------------------------------------------------
>19327_19327_7_CREB3L2-MACC1_CREB3L2_chr7_137686350_ENST00000456390_MACC1_chr7_20194004_ENST00000332878_length(transcript)=1187nt_BP=464nt
GTCCCTCAAAGTTTGTGTCTGGAGCCGTAGCGGCAAGTGGGCTTGCGGCTAAGGGATTTTCCTGGGATGAGAGCGGGTCTTCTGCCTTCA
TTTTGGATGCACATCCCGCTTTAGCCCCGGCAGCCTTTGGTCCGGCTCGTGTCCCTGGGGATTCTCGGATCTCCGAGGACACCGGACGGG
AGCGCTTGGCCATCCTCTCTCCGGCAGAGGAGCAGACGTTTGCTTTCCAAGTGCAAAACTACAGACACGCGCGCGCACACACGCAAGCAC
ACGCGGAGAGAGAGGAACCTTGCCGGTCCGAGGCAGCTCTGCGCGTCCCCTCCTGCGCTTAGCATCCTCGGCCCAGCGCGGCCCGCACCG
CCATGGAGGTGCTGGAGAGCGGGGAGCAGGGCGTGCTGCAGTGGGACCGCAAGCTGAGCGAGCTGTCAGAGCCCGGGGACGGCGAGGCCC
TCATGTACCACACGGCTCTTCTGAAAATGGATTGCCAAGAGTTAGTCGCACGTCTCATCCAAGAAGCTGCTGTTCTGACTTCAGCTGTCA
AGCTTGGAAAAGGCTGGAGGGAACTAGCTGAAAAGTTAGTACGACTCACAAAGCAACAAATGGAGGCATATGAAATTCCTCATCGAGGAA
ACACTGGAGATGTTGCTGTTGAGATGATGTGGAAACCTGCCTATGATTTTCTGTATACCTGGAGTGCTCACTATGGAAATAACTACAGAG
ATGTGTTACAAGACCTTCAGTCAGCTTTGGACAGAATGAAAAACCCTGTGACTAAACACTGGAGAGAATTAACTGGAGTTTTAATACTAG
TAAATTCTTTGGAGGTTTTGAGAGTAACTGCATTCTCCACTTCTGAGGAAGTATAGAAACAAAGCGTGTGTTTTTGATGGGAGGGAAAAT
GAGGTAATGGTGTGTGTGTGTGTGTGTCTGTGTGTGTCTGTGTGTGTCTCTGTGTGTCTGTGTGTGTGTGTCTGTGTGTGTGTGTCTGTG
TGTGTGTGTGTGTGTGTGTAGGAAAGAAAGAATCTCAGAAAAGCATTATATTAATTTTCTTCATGCTCAAAACCAGTTTTTTTTTCCTGA
TGAAAGCACAGCCTAACTGATAACCAAGATGGGTTTTATCCTCAAATATGTATTTTTGTGTATGTTTCAAATACAAGTATTAGGCTGCTT

>19327_19327_7_CREB3L2-MACC1_CREB3L2_chr7_137686350_ENST00000456390_MACC1_chr7_20194004_ENST00000332878_length(amino acids)=167AA_BP=34
MEVLESGEQGVLQWDRKLSELSEPGDGEALMYHTALLKMDCQELVARLIQEAAVLTSAVKLGKGWRELAEKLVRLTKQQMEAYEIPHRGN

--------------------------------------------------------------
>19327_19327_8_CREB3L2-MACC1_CREB3L2_chr7_137686350_ENST00000456390_MACC1_chr7_20194004_ENST00000400331_length(transcript)=7157nt_BP=464nt
GTCCCTCAAAGTTTGTGTCTGGAGCCGTAGCGGCAAGTGGGCTTGCGGCTAAGGGATTTTCCTGGGATGAGAGCGGGTCTTCTGCCTTCA
TTTTGGATGCACATCCCGCTTTAGCCCCGGCAGCCTTTGGTCCGGCTCGTGTCCCTGGGGATTCTCGGATCTCCGAGGACACCGGACGGG
AGCGCTTGGCCATCCTCTCTCCGGCAGAGGAGCAGACGTTTGCTTTCCAAGTGCAAAACTACAGACACGCGCGCGCACACACGCAAGCAC
ACGCGGAGAGAGAGGAACCTTGCCGGTCCGAGGCAGCTCTGCGCGTCCCCTCCTGCGCTTAGCATCCTCGGCCCAGCGCGGCCCGCACCG
CCATGGAGGTGCTGGAGAGCGGGGAGCAGGGCGTGCTGCAGTGGGACCGCAAGCTGAGCGAGCTGTCAGAGCCCGGGGACGGCGAGGCCC
TCATGTACCACACGGCTCTTCTGAAAATGGATTGCCAAGAGTTAGTCGCACGTCTCATCCAAGAAGCTGCTGTTCTGACTTCAGCTGTCA
AGCTTGGAAAAGGCTGGAGGGAACTAGCTGAAAAGTTAGTACGACTCACAAAGCAACAAATGGAGGCATATGAAATTCCTCATCGAGGAA
ACACTGGAGATGTTGCTGTTGAGATGATGTGGAAACCTGCCTATGATTTTCTGTATACCTGGAGTGCTCACTATGGAAATAACTACAGAG
ATGTGTTACAAGACCTTCAGTCAGCTTTGGACAGAATGAAAAACCCTGTGACTAAACACTGGAGAGAATTAACTGGAGTTTTAATACTAG
TAAATTCTTTGGAGGTTTTGAGAGTAACTGCATTCTCCACTTCTGAGGAAGTATAGAAACAAAGCGTGTGTTTTTGATGGGAGGGAAAAT
GAGGTAATGGTGTGTGTGTGTGTGTGTCTGTGTGTGTCTGTGTGTGTCTCTGTGTGTCTGTGTGTGTGTGTCTGTGTGTGTGTGTCTGTG
TGTGTGTGTGTGTGTGTGTAGGAAAGAAAGAATCTCAGAAAAGCATTATATTAATTTTCTTCATGCTCAAAACCAGTTTTTTTTTCCTGA
TGAAAGCACAGCCTAACTGATAACCAAGATGGGTTTTATCCTCAAATATGTATTTTTGTGTATGTTTCAAATACAAGTATTAGGCTGCTT
TGTTCTTAGAAAGGAAAGAAAAAAGAAAAGTGCCCTCTCTCTCTTTCAGTGTTATTTTAAATTTACTAAGTCAAAGCTGTTTGAATAATT
ACATCACACAGATATCTGGGTAAACTAGAGACTATCAACATGATCAAGGCAGTGTTCCCAGGAGGCAGCTAGAAAGAGGGGAAGCAAGCA
CACACCCTGTGGCCAGTCACGGCTGCCCGCTTTCCACACCTGACCTCTTCAGTTCATCAGTGGGGTTCACCAGCATCACCCCCATTTTTC
ATGGGGAGAAACTCAGAAGTGGAGAGAACGTCTGAGGCTACATAGCCAGTACAAAGTAGGTTTTCTGCTTGAAAAACCTGTTTCTATTTC
TTTTTAAAAAATCATACTGCATAACAGAATAGTAAAAACAAAATGCGTGTTAAGACTTACAGGGAAACAGTTGCCGTTTCATTTTAAGTG
AGACTTGCTACTCTTTTTCATCGTCTCTTGAAAGACTGACAGAAGGAAAATATGACTTATCAGAAATCTGTTGTCTGCATGCATGGACCT
AGTGTTTTCATCAGCTCCCTTCAGCATCTTGGGACCTCTCTAATCCTGCCTAATTTGGGACTTTTTCTGCAGGATTGTAATGTAAAATAG
TTCTTTAGCTCTTGGAGATTTTTAATAATACGAGTTATTAAAAACCACCACCACCAGAAACTTGATTAACTTGATTACCCTGTTGAGTAG
AGAGGTCTTAACCACCGAAAACACTGATATCTTTATGTTGGCATGCTCATGCAAACACATGTGTGTGTGTGTGTGTGTGTGTGTGTGTGT
GTGTGTACCACAGTGTTTTATAAAGCACAGCCTAATTGATTATATAGGACAAAAATTGTATAGGACCCTGGGTCAGTATAAATGCTAATG
GCTGACAAAGTTCACAAAGAGATGTATTTTGCTTACTCCTCTGTTCAATCCTCTGGTTGCCTGCCAGTGTTTATGTGTGTATTTGGACAG
ACATTCATTTATTGTCATTCAGTCAATAGGTAGAGTATATGTGTCTATTTTTTGGCAGGCATATAGATGCTTGAGGCTAATGGGAAAAAA
CCAGCATGAACTCTGACTTTAGTAGTGCTAAGTAATAGATAATTTTAAAAAATGACACCGTTAAATAGAAAATGGCATGCATACTAACAG
TTGCAATGGAGAGGCTGTGATGCTACGAGATATAAACGTAGAGATGCCATCATGTGAAACTGGAAGTGGGGGTGGGTCAGGGAAATTTGT
TCTTGGAAAGAAATAATGAACCTCAAGGAAGAGTAGGCATTGTCCTGGTGTGGTGGGGTGTAAGCGGTGATCCCACAAAGCACTGAAGCT
CTTAGATGGGTGGGAGCTGAATAGGTGCAGATAGCAGGGGTGAAGGAGTGAAAGGATAAAAGATTCAAGGTTGAGATGAGGATGGAGCAA
GAAGAAGCCACATTAGGGCCATTAAGGCTGCTAGAATTTAGAAAGAAAACACACAGCCTCAAAGAAATGTGGGTAAGCCAAAGAAGGATT
TTGTTTTGGGAACCTGAATAAAAGATGTCCATTTGGCTAAAAAGTAAAAGCAGAATCTTTTTAGGGCTTTTAATATACCCACCCTGGGAT
ATTTGGTATGCTGGCAATGGTAATTCAAATTGGCGTTTAAGAATAATCTTGGCCGGGCGCGATGGCTCATGCCTGAAATCCCAGCACTTT
GGGAGGCCGAGGCGGGCAGATCACTAGGTCAGGAGATCGAGACCATCCTGGCTAACGCGGTGAAACCCCGTCTCTACTAAAAATACAAAA
AATTAGCCGGGCGTGGTGGCAGGCGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCGGAGCTT
GCAGTGAGCCGAGTTCATGCCACTGCACTCCAGCCTGGGTGACAGGCTGTCTCAAAAAAAAAAAAAGGAATAATCTGTACGGCTTTCAGT
ATTTATATTTGATTATAAGGGAACACAGCCTGACCAAATAATTATGTATACACATTCAAGGACAGAATTTATTTTAATTAAAAATAAATT
ATGAGAGAAGGAAAAAAAAGCACAGTTTTTACTTTCAGAACACAGTCCTTTTTTGTGGTGATTTTGCTTTCTTTAGAACATTCTTGGAAT
CTTATTAACATGTCAGCTAACCAGAGAATTTTGGGAAGGGATAGTGGGGATTAATAACTGGGTTTTTCCAGGCTCCAAGATCTAAGAAGA
CAGAGATCTTGTTAGCTGATTAGTGTAGTAAGATTAAATAAATAATTTAAGGTTTACATTGCATCATGTATTATGATTGTGATTGAGAAT
AATAAGAGTTTAAAAAAATGAAAAACAAGATCTCTGTAATTTGAGGATGAAACAATGGTTCTAATATTAATACACACAAATATATTTTAT
AATCTTGTAACAAATCCTTCCAGGGGAAATTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGCCAGAGTCTGGCTCTGTTGCCCAGACTG
GAGTGCGGTGTTTCAATCTTGACTCACTGCAACCTCCACCTCCTGGGTTCAAAAGATCCTTCTGCCTCCGCCTCCCAAGTAGCTGGGATT
ACAGGCATGCACCACCTTGTCCGGGTAATTTTTGTATTTTTAGTGGAGACAAGGTTTTACCATTTTGGCCAGACTGGTCTGGAACTCCTG
ACCTCAGGTCATCCACCTGCCTCGGCCTCCCAGAGTGCTAGGATTACAGGCATGAGCCACTGCTCCCAGCCTTCCAGAGGAATTTTAAGC
CCATGTCCAAACATTCTGTTTGTATAAATATATTCTAATTTTTAAATAAATAGTTTCTACTTTTCTGAACTTTATATTTTTTCTTGCTAT
AATGGATTTTCATAATCAGAAAAGATTAAATTAGTAATCATGAATTGCCTTCAATATTTGGCAGTAAGTCAATGAAATAATAAGGCACTT
ATATACCATCTTTGACATCATTAAAAGTATCAAATCCCATTAATCTAAAACTTCTTTAAGCATTTTGAAAGCAGAAAATGTTTACATGGT
TCTTTCAGTTCCTCAGGCTTTTTGTCTAATGATGCGTGACTTAGGATAAGATTTGAATTAAGTGCCCAGCTTGAAACATAATAATTTTTC
TGTATAAGCCACAGATCCTCTACCTCCTTTGTGTTAAAGCCTTTATATGAAACAATTAAGTAGAAGCATTCAATAGTGTGTCATTAACTG
TTCATACTAATAAATGGATACAGCACATTTTCATGGCCTGTAATGTAGAACATACTATATAAAGTTCTCAGTTTGGGGATGACTAGGTTT
CTGGAAGGAATAGAATGCTAAATCAATGGATGGCATTGGGCTGAGAAACACTGCTGCTACTAATCAGCCTTGAATGTGTAATGTGAACAT
GCAAAAGAGAACATGCATACACTCAAATTTGTACAATGCTATAACTGGAAGTTGAAGGACTTGAATTTTTATATTGTGCTATTGTTATGT
TTTCTGTAATTGTTTATATCTAAGGAATTTTTGAGGTAATATAAAAGAAAAAGAGAATAATGAACAATGATGTCACTGGAGGGTTTTTAC
ATTAAATTAGATCATTTTTCTTCTTATTCACAATAATAATCTTAATCTTTAAGAATTAATTATAATTTAATATTATAATTCATAATCTTT
AAGAATTAATAATTATAATTTAATATTATAATTAATAATCTTTAAGAATTAATAATATAATTTAATATTATAATTAATAATCTTTAAGAA
TTAATAATTACAATTAATAATTAATAATAATCTTAATCTTTAAGAATTAATAATAATCCTTAATCGCAATAATAATCGCAAGGAGGAGAA
GTAAGTCCCTCCTCCTTCTGTATGAACTTTTCTCCCACATGCTGCTGTATGGTTTAGTGAGAGTGAAGTTCTAAAGAACATCAATATGAT
TGGTGGGATAATCCAAAGACATTTTTTCAGAATCAAATGGCATGTCGAAGGTTTGTTTCTTGCATATGTATTTACTGGTCCACAGCACAA
AATAAAGTGACCACATATACATAGGAAAGTTGAATTTGTACACATACAGCATCTGAAATGTATCTGATGTTCAGCATCAAGATTTCACTG
AACATTGTAGAAATGTGTATCTTTTGCATGTATATTTTACATTGATTTTCTATTTATGTACATCTAGAAAGTTTTAACCCTAATAAATAG
TTTTGTAATTTTGAATAATAGTGTCAGTTTATATGTGAGGGAGTAGAGACAGAGAGGTTAGCACTGGATAATAATTAGTAAGGCCAAAGG
AGAAAATTTCATAGAAAATATTGTTGTTGTCATAATGAGTACAGCATGAAAGGCTTCCTCTACAAGACACTAGTCAAAGAGTTGAGAGCT
GCGGTTTCTAATCTTTGTCCATTACTCCCTTACTCCCTATGAGACTGTGGACCTGTCACTTGGCCTCTCTGGTCTTCAGTTTTCTCACCA
GTAAAACAAGGAACTTGAACCAAATGACCTCTAGTGTTCCCCTTGGGTTTAAATGTCTATAAATGTTCAATGACTAGAATGTATTGCGTT
TTTCTTTATTCTTTTTGCTTTGAGAAAAGAGAATGTGATTTAAGAGTAATAATTTGAATACCAATTATCCACATTAAAATTGTGTCCTCT
ATGTGTAAGGCATAGCACATTTAGCACACATACATAAGCACACTAAGCACCTTACAAATATCCTCATTTATTCTTTACATAATCTTTTGA
AATTGATTATGTAATACACACTGTTTTTGAACAATTGGTGACTTCCAGCTGTTTAAAACAAACTACAGTATGGTGCTTGAGTACTGACTT
AGGAGGTCAGCATTGGTTTCACTAGGAGCTTCTCAAAGCACGCTGCCAAACATGCTCCAGTCTCATTGTCAAGGCCTTAGACCAGGCAAT
CATTACGGCAGTGGTTCTTCAACTTCAGCAGCAGCAAAACGATCTGGCGGGGGCTTGGTGAAACAGACTGCTGGGCTCGACCACCAGAAT
TTCTCATTCAGAGGGTCTGGCCTGATCACTTGCATTTCTAATCACTTCCCAGGTGATGCAGATGTTTCTGGTCCAGGGACCCCAGTTTGA
GAACCACTGTATTAAAATTTCCTTCATCTCTATAGAAATGGAAAGATTTTTTATAAGTCCTCTAATTTGCTTTAAGATAAATGAGATTTC
ACTTAATTCTGTTGGAGAAATTGTTTTAAAAATTGTGCTAAAGAACCGAAAATCACTTTATGTTAAGGCTCTATTTATAGCAAGTGAACT
TTTCATGAGTTAATAAAGGCCTACAAAAATAATTTTGACTGTGAAACTAATTAAAATCTCTGTGTTTCATTTAAAGCATAAACATATTTG
AATAAAAATAGGTTAACAATAATTTGGGACATGTATTCAGTATAATTTTAAGATAATTTTACAAAATATATGTAACATTGCATTTGTTTC
TGTAAAATATCTTCGGAAAAAGCCTTGTTTTCCCTAGTGTGTTATTTGTTGAATTTCTTGTTAAATGTATTTTTTCCCATTGAAAAAAAT
GTTTTTAATCAATGTGATCAATACAGCTATCTATATGCCCTGCTTTCACTGTAGAATTAGAAAGTGTTAATAAGGTGATCGGATGTTCTT
TCTAAGGATCATATTCCACATTTAAAGAGATGGTGACTGAGAAGAGGTGGCAAGCTGAACCATCTCACTTTGAGATTGACGTATCACGTT
TTATCCTCTGCCATCATTTCCTTGTTAATTGTTTTTCTTTGGGTGATTGGAAGAATCTATGGCTTCCTTTTCTCTGTTCTTAAAGATATC
AAGACTCTGCCCTTTTGTGACTGGAAGTAGATTTTAAATGTCCCTAATGTTTATATGCTCACTTAAACTCAATACATGGAATTTACTGGG

>19327_19327_8_CREB3L2-MACC1_CREB3L2_chr7_137686350_ENST00000456390_MACC1_chr7_20194004_ENST00000400331_length(amino acids)=167AA_BP=34
MEVLESGEQGVLQWDRKLSELSEPGDGEALMYHTALLKMDCQELVARLIQEAAVLTSAVKLGKGWRELAEKLVRLTKQQMEAYEIPHRGN

--------------------------------------------------------------
>19327_19327_9_CREB3L2-MACC1_CREB3L2_chr7_137686350_ENST00000456390_MACC1_chr7_20194004_ENST00000589011_length(transcript)=895nt_BP=464nt
GTCCCTCAAAGTTTGTGTCTGGAGCCGTAGCGGCAAGTGGGCTTGCGGCTAAGGGATTTTCCTGGGATGAGAGCGGGTCTTCTGCCTTCA
TTTTGGATGCACATCCCGCTTTAGCCCCGGCAGCCTTTGGTCCGGCTCGTGTCCCTGGGGATTCTCGGATCTCCGAGGACACCGGACGGG
AGCGCTTGGCCATCCTCTCTCCGGCAGAGGAGCAGACGTTTGCTTTCCAAGTGCAAAACTACAGACACGCGCGCGCACACACGCAAGCAC
ACGCGGAGAGAGAGGAACCTTGCCGGTCCGAGGCAGCTCTGCGCGTCCCCTCCTGCGCTTAGCATCCTCGGCCCAGCGCGGCCCGCACCG
CCATGGAGGTGCTGGAGAGCGGGGAGCAGGGCGTGCTGCAGTGGGACCGCAAGCTGAGCGAGCTGTCAGAGCCCGGGGACGGCGAGGCCC
TCATGTACCACACGGCTCTTCTGAAAATGGATTGCCAAGAGTTAGTCGCACGTCTCATCCAAGAAGCTGCTGTTCTGACTTCAGCTGTCA
AGCTTGGAAAAGGCTGGAGGGAACTAGCTGAAAAGTTAGTACGACTCACAAAGCAACAAATGGAGGCATATGAAATTCCTCATCGAGGAA
ACACTGGAGATGTTGCTGTTGAGATGATGTGGAAACCTGCCTATGATTTTCTGTATACCTGGAGTGCTCACTATGGAAATAACTACAGAG
ATGTGTTACAAGACCTTCAGTCAGCTTTGGACAGAATGAAAAACCCTGTGACTAAACACTGGAGAGAATTAACTGGAGTTTTAATACTAG

>19327_19327_9_CREB3L2-MACC1_CREB3L2_chr7_137686350_ENST00000456390_MACC1_chr7_20194004_ENST00000589011_length(amino acids)=167AA_BP=34
MEVLESGEQGVLQWDRKLSELSEPGDGEALMYHTALLKMDCQELVARLIQEAAVLTSAVKLGKGWRELAEKLVRLTKQQMEAYEIPHRGN

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CREB3L2-MACC1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CREB3L2-MACC1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CREB3L2-MACC1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource