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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CREBBP-TCEB2 (FusionGDB2 ID:19385)

Fusion Gene Summary for CREBBP-TCEB2

check button Fusion gene summary
Fusion gene informationFusion gene name: CREBBP-TCEB2
Fusion gene ID: 19385
HgeneTgene
Gene symbol

CREBBP

TCEB2

Gene ID

1387

6923

Gene nameCREB binding proteinelongin B
SynonymsCBP|KAT3A|MKHK1|RSTS|RSTS1SIII|TCEB2
Cytomap

16p13.3

16p13.3

Type of geneprotein-codingprotein-coding
DescriptionCREB-binding proteinhistone lysine acetyltransferase CREBBPprotein-lysine acetyltransferase CREBBPelongin-BRNA polymerase II transcription factor SIII p18 subunitRNA polymerase II transcription factor SIII subunit BSIII p18elongin 18 kDa subunitelongin, 18-kD subunitepididymis secretory sperm binding proteintranscription elongation factor B (SI
Modification date2020032920200313
UniProtAcc

Q92793

.
Ensembl transtripts involved in fusion geneENST00000262367, ENST00000382070, 
ENST00000409477, ENST00000572954, 
ENST00000262306, ENST00000409906, 
Fusion gene scores* DoF score43 X 38 X 17=277785 X 4 X 5=100
# samples 617
** MAII scorelog2(61/27778*10)=-5.50898967694577
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/100*10)=-0.514573172829758
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CREBBP [Title/Abstract] AND TCEB2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCREBBP(3929832)-TCEB2(2827128), # samples:1
CREBBP(3929833)-TCEB2(2827128), # samples:1
CREBBP(3929832)-TCEB2(2827127), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCREBBP

GO:0000122

negative regulation of transcription by RNA polymerase II

21539536

HgeneCREBBP

GO:0006355

regulation of transcription, DNA-templated

12169688

HgeneCREBBP

GO:0006473

protein acetylation

15273251|24207024|24939902|28790157|30540930

HgeneCREBBP

GO:0016573

histone acetylation

11742995

HgeneCREBBP

GO:0018076

N-terminal peptidyl-lysine acetylation

12435739

HgeneCREBBP

GO:0034644

cellular response to UV

24939902

HgeneCREBBP

GO:0045893

positive regulation of transcription, DNA-templated

11742995

HgeneCREBBP

GO:1990258

histone glutamine methylation

30540930


check buttonFusion gene breakpoints across CREBBP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TCEB2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-33-4587-01ACREBBPchr16

3929832

-TCEB2chr16

2827127

-
ChimerDB4LUSCTCGA-33-4587CREBBPchr16

3929832

-TCEB2chr16

2827128

-
ChimerDB4LUSCTCGA-33-4587CREBBPchr16

3929833

-TCEB2chr16

2827128

-


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Fusion Gene ORF analysis for CREBBP-TCEB2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000262367ENST00000409477CREBBPchr16

3929832

-TCEB2chr16

2827127

-
5CDS-5UTRENST00000262367ENST00000409477CREBBPchr16

3929832

-TCEB2chr16

2827128

-
5CDS-5UTRENST00000262367ENST00000409477CREBBPchr16

3929833

-TCEB2chr16

2827128

-
5CDS-5UTRENST00000262367ENST00000572954CREBBPchr16

3929832

-TCEB2chr16

2827127

-
5CDS-5UTRENST00000262367ENST00000572954CREBBPchr16

3929832

-TCEB2chr16

2827128

-
5CDS-5UTRENST00000262367ENST00000572954CREBBPchr16

3929833

-TCEB2chr16

2827128

-
5CDS-5UTRENST00000382070ENST00000409477CREBBPchr16

3929832

-TCEB2chr16

2827127

-
5CDS-5UTRENST00000382070ENST00000409477CREBBPchr16

3929832

-TCEB2chr16

2827128

-
5CDS-5UTRENST00000382070ENST00000409477CREBBPchr16

3929833

-TCEB2chr16

2827128

-
5CDS-5UTRENST00000382070ENST00000572954CREBBPchr16

3929832

-TCEB2chr16

2827127

-
5CDS-5UTRENST00000382070ENST00000572954CREBBPchr16

3929832

-TCEB2chr16

2827128

-
5CDS-5UTRENST00000382070ENST00000572954CREBBPchr16

3929833

-TCEB2chr16

2827128

-
In-frameENST00000262367ENST00000262306CREBBPchr16

3929832

-TCEB2chr16

2827127

-
In-frameENST00000262367ENST00000262306CREBBPchr16

3929832

-TCEB2chr16

2827128

-
In-frameENST00000262367ENST00000262306CREBBPchr16

3929833

-TCEB2chr16

2827128

-
In-frameENST00000262367ENST00000409906CREBBPchr16

3929832

-TCEB2chr16

2827127

-
In-frameENST00000262367ENST00000409906CREBBPchr16

3929832

-TCEB2chr16

2827128

-
In-frameENST00000262367ENST00000409906CREBBPchr16

3929833

-TCEB2chr16

2827128

-
In-frameENST00000382070ENST00000262306CREBBPchr16

3929832

-TCEB2chr16

2827127

-
In-frameENST00000382070ENST00000262306CREBBPchr16

3929832

-TCEB2chr16

2827128

-
In-frameENST00000382070ENST00000262306CREBBPchr16

3929833

-TCEB2chr16

2827128

-
In-frameENST00000382070ENST00000409906CREBBPchr16

3929832

-TCEB2chr16

2827127

-
In-frameENST00000382070ENST00000409906CREBBPchr16

3929832

-TCEB2chr16

2827128

-
In-frameENST00000382070ENST00000409906CREBBPchr16

3929833

-TCEB2chr16

2827128

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000262367CREBBPchr163929832-ENST00000262306TCEB2chr162827128-14368957351245
ENST00000262367CREBBPchr163929832-ENST00000409906TCEB2chr162827128-18258957351245
ENST00000382070CREBBPchr163929832-ENST00000262306TCEB2chr162827128-830289208771187
ENST00000382070CREBBPchr163929832-ENST00000409906TCEB2chr162827128-1219289798253181
ENST00000262367CREBBPchr163929833-ENST00000262306TCEB2chr162827128-14368957351245
ENST00000262367CREBBPchr163929833-ENST00000409906TCEB2chr162827128-18258957351245
ENST00000382070CREBBPchr163929833-ENST00000262306TCEB2chr162827128-830289208771187
ENST00000382070CREBBPchr163929833-ENST00000409906TCEB2chr162827128-1219289798253181
ENST00000262367CREBBPchr163929832-ENST00000262306TCEB2chr162827127-14368957351245
ENST00000262367CREBBPchr163929832-ENST00000409906TCEB2chr162827127-18258957351245
ENST00000382070CREBBPchr163929832-ENST00000262306TCEB2chr162827127-830289208771187
ENST00000382070CREBBPchr163929832-ENST00000409906TCEB2chr162827127-1219289798253181

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000262367ENST00000262306CREBBPchr163929832-TCEB2chr162827128-0.0917551140.9082449
ENST00000262367ENST00000409906CREBBPchr163929832-TCEB2chr162827128-0.0592846420.9407153
ENST00000382070ENST00000262306CREBBPchr163929832-TCEB2chr162827128-0.104474870.89552516
ENST00000382070ENST00000409906CREBBPchr163929832-TCEB2chr162827128-0.0356881580.9643119
ENST00000262367ENST00000262306CREBBPchr163929833-TCEB2chr162827128-0.0917551140.9082449
ENST00000262367ENST00000409906CREBBPchr163929833-TCEB2chr162827128-0.0592846420.9407153
ENST00000382070ENST00000262306CREBBPchr163929833-TCEB2chr162827128-0.104474870.89552516
ENST00000382070ENST00000409906CREBBPchr163929833-TCEB2chr162827128-0.0356881580.9643119
ENST00000262367ENST00000262306CREBBPchr163929832-TCEB2chr162827127-0.0917551140.9082449
ENST00000262367ENST00000409906CREBBPchr163929832-TCEB2chr162827127-0.0592846420.9407153
ENST00000382070ENST00000262306CREBBPchr163929832-TCEB2chr162827127-0.104474870.89552516
ENST00000382070ENST00000409906CREBBPchr163929832-TCEB2chr162827127-0.0356881580.9643119

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Fusion Genomic Features for CREBBP-TCEB2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CREBBP-TCEB2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:3929832/chr16:2827128)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CREBBP

Q92793

.
FUNCTION: Acetylates histones, giving a specific tag for transcriptional activation (PubMed:24616510). Also acetylates non-histone proteins, like DDX21, FBL, IRF2, MAFG, NCOA3, POLR1E/PAF53 and FOXO1 (PubMed:10490106, PubMed:11154691, PubMed:12738767, PubMed:12929931, PubMed:9707565, PubMed:24207024, PubMed:28790157, PubMed:30540930). Binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers (PubMed:14645221). Acetylates PCNA; acetylation promotes removal of chromatin-bound PCNA and its degradation during nucleotide excision repair (NER) (PubMed:24939902). Acetylates POLR1E/PAF53, leading to decreased association of RNA polymerase I with the rDNA promoter region and coding region (PubMed:24207024). Acetylates DDX21, thereby inhibiting DDX21 helicase activity (PubMed:28790157). Acetylates FBL, preventing methylation of 'Gln-105' of histone H2A (H2AQ104me) (PubMed:30540930). Functions as a transcriptional coactivator for SMAD4 in the TGF-beta signaling pathway (PubMed:25514493). {ECO:0000269|PubMed:10490106, ECO:0000269|PubMed:11154691, ECO:0000269|PubMed:12738767, ECO:0000269|PubMed:12929931, ECO:0000269|PubMed:14645221, ECO:0000269|PubMed:24207024, ECO:0000269|PubMed:24616510, ECO:0000269|PubMed:24939902, ECO:0000269|PubMed:25514493, ECO:0000269|PubMed:28790157, ECO:0000269|PubMed:30540930, ECO:0000269|PubMed:9707565}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTCEB2chr16:3929832chr16:2827127ENST00000262306051_661162.0DomainUbiquitin-like
TgeneTCEB2chr16:3929832chr16:2827127ENST00000409906041_661119.0DomainUbiquitin-like
TgeneTCEB2chr16:3929832chr16:2827128ENST00000262306051_661162.0DomainUbiquitin-like
TgeneTCEB2chr16:3929832chr16:2827128ENST00000409906041_661119.0DomainUbiquitin-like
TgeneTCEB2chr16:3929833chr16:2827128ENST00000262306051_661162.0DomainUbiquitin-like
TgeneTCEB2chr16:3929833chr16:2827128ENST00000409906041_661119.0DomainUbiquitin-like

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-1311061_1064282443.0Compositional biasNote=Poly-Glu
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-1311199_1487282443.0Compositional biasNote=Cys/His-rich
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-1311555_1562282443.0Compositional biasNote=Poly-Glu
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-1311943_1948282443.0Compositional biasNote=Poly-Pro
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-1311967_1970282443.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-1312081_2085282443.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-1312199_2216282443.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-1312245_2248282443.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-1312297_2300282443.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-1301061_1064282405.0Compositional biasNote=Poly-Glu
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-1301199_1487282405.0Compositional biasNote=Cys/His-rich
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-1301555_1562282405.0Compositional biasNote=Poly-Glu
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-1301943_1948282405.0Compositional biasNote=Poly-Pro
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-1301967_1970282405.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-1302081_2085282405.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-1302199_2216282405.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-1302245_2248282405.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-1302297_2300282405.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-1311061_1064282443.0Compositional biasNote=Poly-Glu
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-1311199_1487282443.0Compositional biasNote=Cys/His-rich
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-1311555_1562282443.0Compositional biasNote=Poly-Glu
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-1311943_1948282443.0Compositional biasNote=Poly-Pro
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-1311967_1970282443.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-1312081_2085282443.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-1312199_2216282443.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-1312245_2248282443.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-1312297_2300282443.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-1301061_1064282405.0Compositional biasNote=Poly-Glu
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-1301199_1487282405.0Compositional biasNote=Cys/His-rich
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-1301555_1562282405.0Compositional biasNote=Poly-Glu
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-1301943_1948282405.0Compositional biasNote=Poly-Pro
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-1301967_1970282405.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-1302081_2085282405.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-1302199_2216282405.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-1302245_2248282405.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-1302297_2300282405.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-1311061_1064282443.0Compositional biasNote=Poly-Glu
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-1311199_1487282443.0Compositional biasNote=Cys/His-rich
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-1311555_1562282443.0Compositional biasNote=Poly-Glu
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-1311943_1948282443.0Compositional biasNote=Poly-Pro
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-1311967_1970282443.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-1312081_2085282443.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-1312199_2216282443.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-1312245_2248282443.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-1312297_2300282443.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-1301061_1064282405.0Compositional biasNote=Poly-Glu
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-1301199_1487282405.0Compositional biasNote=Cys/His-rich
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-1301555_1562282405.0Compositional biasNote=Poly-Glu
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-1301943_1948282405.0Compositional biasNote=Poly-Pro
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-1301967_1970282405.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-1302081_2085282405.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-1302199_2216282405.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-1302245_2248282405.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-1302297_2300282405.0Compositional biasNote=Poly-Gln
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-1311103_1175282443.0DomainBromo
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-1311323_1700282443.0DomainCBP/p300-type HAT
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-131587_666282443.0DomainKIX
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-1301103_1175282405.0DomainBromo
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-1301323_1700282405.0DomainCBP/p300-type HAT
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-130587_666282405.0DomainKIX
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-1311103_1175282443.0DomainBromo
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-1311323_1700282443.0DomainCBP/p300-type HAT
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-131587_666282443.0DomainKIX
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-1301103_1175282405.0DomainBromo
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-1301323_1700282405.0DomainCBP/p300-type HAT
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-130587_666282405.0DomainKIX
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-1311103_1175282443.0DomainBromo
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-1311323_1700282443.0DomainCBP/p300-type HAT
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-131587_666282443.0DomainKIX
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-1301103_1175282405.0DomainBromo
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-1301323_1700282405.0DomainCBP/p300-type HAT
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-130587_666282405.0DomainKIX
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-1311434_1436282443.0RegionAcetyl-CoA binding
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-1311446_1447282443.0RegionAcetyl-CoA binding
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-1301434_1436282405.0RegionAcetyl-CoA binding
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-1301446_1447282405.0RegionAcetyl-CoA binding
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-1311434_1436282443.0RegionAcetyl-CoA binding
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-1311446_1447282443.0RegionAcetyl-CoA binding
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-1301434_1436282405.0RegionAcetyl-CoA binding
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-1301446_1447282405.0RegionAcetyl-CoA binding
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-1311434_1436282443.0RegionAcetyl-CoA binding
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-1311446_1447282443.0RegionAcetyl-CoA binding
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-1301434_1436282405.0RegionAcetyl-CoA binding
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-1301446_1447282405.0RegionAcetyl-CoA binding
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-1311701_1744282443.0Zinc fingerZZ-type
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-1311765_1846282443.0Zinc fingerTAZ-type 2
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-131347_433282443.0Zinc fingerTAZ-type 1
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-1301701_1744282405.0Zinc fingerZZ-type
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-1301765_1846282405.0Zinc fingerTAZ-type 2
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-130347_433282405.0Zinc fingerTAZ-type 1
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-1311701_1744282443.0Zinc fingerZZ-type
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-1311765_1846282443.0Zinc fingerTAZ-type 2
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-131347_433282443.0Zinc fingerTAZ-type 1
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-1301701_1744282405.0Zinc fingerZZ-type
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-1301765_1846282405.0Zinc fingerTAZ-type 2
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-130347_433282405.0Zinc fingerTAZ-type 1
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-1311701_1744282443.0Zinc fingerZZ-type
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-1311765_1846282443.0Zinc fingerTAZ-type 2
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-131347_433282443.0Zinc fingerTAZ-type 1
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-1301701_1744282405.0Zinc fingerZZ-type
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-1301765_1846282405.0Zinc fingerTAZ-type 2
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-130347_433282405.0Zinc fingerTAZ-type 1


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Fusion Gene Sequence for CREBBP-TCEB2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>19385_19385_1_CREBBP-TCEB2_CREBBP_chr16_3929832_ENST00000262367_TCEB2_chr16_2827127_ENST00000262306_length(transcript)=1436nt_BP=895nt
TTCTTTTTTTTTTAATTGAGGAATCAACAGCCGCCATCTTGTCGCGGACCCGACCGGGGCTTCGAGCGCGATCTACTCGGCCCCGCCGGT
CCCGGGCCCCACAACCGCCCGCGCACCCCGCTCCGCCCGGCCGGCCCGCTCCGCCCGGCCCTCGGCGCCCGCCCCGGCGGCCCCGCTCGC
CTCTCGGCTCGGCCTCCCGGAGCCCGGCGGCGGCGGCGGCGGCAGCGGCGGCGGCGGCGGCGGAACGGGGGGTGGGGGGGCCGCGGCGGC
GGCGGCGACCCCGCTCGGCGCATTGTTTTTCCTCACGGCGGCGGCGGCGGCGGGCCGCGGGCCGGGAGCGGAGCCCGGAGCCCCCTCGTC
GTCGGGCCGCGAGCGAATTCATTAAGTGGGGCGCGGGGGGGGAGCGAGGCGGCGGCGGCGGCGGCACCATGTTCTCGGGGACTGCCTGAG
CCGCCCGGCCGGGCGCCGTCGCTGCCAGCCGGGCCCGGGGGGGCGGCCGGGCCGCCGGGGCGCCCCCACCGCGGAGTGTCGCGCTCGGGA
GGCGGGCAGGGGATGAGGGGGCCGCGGCCGGCGGCGGCGGCGGCGGCCGGGGGCGGGCGGTGAGCGCTGCGGGGCGCTGTTGCTGTGGCT
GAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCGCTCGCGGCCCGCGCTCGCTCCTCT
CCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGGGGCTGTTTTCGCGAGCAGGTGAAA
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGGACGT
GTTCCTCATGATCCGGCGCCACAAGACCACCATCTTCACGGACGCCAAGGAGTCCAGCACGGTGTTCGAACTGAAGCGCATCGTCGAGGG
CATCCTCAAGCGGCCTCCTGACGAGCAGCGGCTGTACAAGGATGACCAACTCTTGGATGATGGCAAGACACTGGGCGAGTGTGGCTTCAC
CAGTCAAACAGCACGGCCACAGGCCCCAGCCACAGTGGGGCTGGCCTTCCGGGCAGATGACACCTTTGAGGCCCTGTGCATCGAGCCGTT
TTCCAGCCCGCCAGAGCTGCCCGATGTGATGAAGCCCCAGGACTCGGGAAGCAGTGCCAATGAACAAGCCGTGCACCTGCATGTCCACTC
CCAGACGATGGCCAAGAGCAGAAACACAAGCTGGAGCCAGTGTCCTGGTTTGACAGCATGTTCAACGAGGGAACCCCAAGACGGACCCAC

>19385_19385_1_CREBBP-TCEB2_CREBBP_chr16_3929832_ENST00000262367_TCEB2_chr16_2827127_ENST00000262306_length(amino acids)=245AA_BP=49
MPAARERSERGPRAGGRAPREREGAGRVGEAAAKSQPQQQRPAALTARPRPPPPPPAAAPSSPARLPSATLRGGGAPAARPPPRARLAAT
APGRAAQAVPENMVPPPPPPRSPPAPHLMNSLAARRRGGSGLRSRPAARRRRRREEKQCAERGRRRRRGPPTPRSAAAAAAAAAAAAGLR

--------------------------------------------------------------
>19385_19385_2_CREBBP-TCEB2_CREBBP_chr16_3929832_ENST00000262367_TCEB2_chr16_2827127_ENST00000409906_length(transcript)=1825nt_BP=895nt
TTCTTTTTTTTTTAATTGAGGAATCAACAGCCGCCATCTTGTCGCGGACCCGACCGGGGCTTCGAGCGCGATCTACTCGGCCCCGCCGGT
CCCGGGCCCCACAACCGCCCGCGCACCCCGCTCCGCCCGGCCGGCCCGCTCCGCCCGGCCCTCGGCGCCCGCCCCGGCGGCCCCGCTCGC
CTCTCGGCTCGGCCTCCCGGAGCCCGGCGGCGGCGGCGGCGGCAGCGGCGGCGGCGGCGGCGGAACGGGGGGTGGGGGGGCCGCGGCGGC
GGCGGCGACCCCGCTCGGCGCATTGTTTTTCCTCACGGCGGCGGCGGCGGCGGGCCGCGGGCCGGGAGCGGAGCCCGGAGCCCCCTCGTC
GTCGGGCCGCGAGCGAATTCATTAAGTGGGGCGCGGGGGGGGAGCGAGGCGGCGGCGGCGGCGGCACCATGTTCTCGGGGACTGCCTGAG
CCGCCCGGCCGGGCGCCGTCGCTGCCAGCCGGGCCCGGGGGGGCGGCCGGGCCGCCGGGGCGCCCCCACCGCGGAGTGTCGCGCTCGGGA
GGCGGGCAGGGGATGAGGGGGCCGCGGCCGGCGGCGGCGGCGGCGGCCGGGGGCGGGCGGTGAGCGCTGCGGGGCGCTGTTGCTGTGGCT
GAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCGCTCGCGGCCCGCGCTCGCTCCTCT
CCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGGGGCTGTTTTCGCGAGCAGGTGAAA
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGGACGT
GTTCCTCATGATCCGGCGCCACAAGACCACCATCTTCACGGACGCCAAGGAGTCCAGCACGGTGTTCGAACTGAAGCGCATCGTCGAGGG
CATCCTCAAGCGGCCTCCTGACGAGCAGCGGCTGTACAAGGATGACCAACTCTTGGATGATGGCAAGACACTGGGCGAGTGTGGCTTCAC
CAGTCAAACAGCACGGCCACAGGCCCCAGCCACAGTGGGGCTGGCCTTCCGGGCAGATGACACCTTTGAGGCCCTGTGCATCGAGCCGTT
TTCCAGCCCGCCAGAGCTGCCCGATGTGATGAAGCCCCAGGACTCGGGAAGCAGTGCCAATGAACAAGCCGTGCAGTGAGGACCCCCAAG
AGGCCCATTTCCCCCAATAAAAGAGATTTGGGAGTCTGCCTGGTTGCTGCCTCTTTTTCCCGCCCCTCCCTGGGATGGGTCCCACTCCCT
GTGGGCTCCTTTTGGGGCTTGTGCTTGGCAGTTCCTGTGCTGTCCTGTCTCCCAGATCCTGAGACCCTGGCTGAGAACTTGGCCCAGCCT
GCTGCTTAAAGGCACCATGGGGACCTGGGTTGCCCTGAGACCCAAGCCATTGTTAGCAGCTAGCCAGCCACACCAACCACGCCAGGGGGA
GGAAAGGGAAGGACTGGGAGAGACACAAAGACCAGAGCCAGCCTCAGGGACAAGAGATTCCAGTTTTAGGCCTTTCTCCTTCTAAGTGCC
CCCCACCCCCATAGCCTGCATGTCCACTCCCAGACGATGGCCAAGAGCAGAAACACAAGCTGGAGCCAGTGTCCTGGTTTGACAGCATGT
TCAACGAGGGAACCCCAAGACGGACCCACACAGGTCCACCCACGCTGGGGGCTGTAATCACGGAGGGAAGTGGCTGCCCCCTTAACACAC

>19385_19385_2_CREBBP-TCEB2_CREBBP_chr16_3929832_ENST00000262367_TCEB2_chr16_2827127_ENST00000409906_length(amino acids)=245AA_BP=49
MPAARERSERGPRAGGRAPREREGAGRVGEAAAKSQPQQQRPAALTARPRPPPPPPAAAPSSPARLPSATLRGGGAPAARPPPRARLAAT
APGRAAQAVPENMVPPPPPPRSPPAPHLMNSLAARRRGGSGLRSRPAARRRRRREEKQCAERGRRRRRGPPTPRSAAAAAAAAAAAAGLR

--------------------------------------------------------------
>19385_19385_3_CREBBP-TCEB2_CREBBP_chr16_3929832_ENST00000262367_TCEB2_chr16_2827128_ENST00000262306_length(transcript)=1436nt_BP=895nt
TTCTTTTTTTTTTAATTGAGGAATCAACAGCCGCCATCTTGTCGCGGACCCGACCGGGGCTTCGAGCGCGATCTACTCGGCCCCGCCGGT
CCCGGGCCCCACAACCGCCCGCGCACCCCGCTCCGCCCGGCCGGCCCGCTCCGCCCGGCCCTCGGCGCCCGCCCCGGCGGCCCCGCTCGC
CTCTCGGCTCGGCCTCCCGGAGCCCGGCGGCGGCGGCGGCGGCAGCGGCGGCGGCGGCGGCGGAACGGGGGGTGGGGGGGCCGCGGCGGC
GGCGGCGACCCCGCTCGGCGCATTGTTTTTCCTCACGGCGGCGGCGGCGGCGGGCCGCGGGCCGGGAGCGGAGCCCGGAGCCCCCTCGTC
GTCGGGCCGCGAGCGAATTCATTAAGTGGGGCGCGGGGGGGGAGCGAGGCGGCGGCGGCGGCGGCACCATGTTCTCGGGGACTGCCTGAG
CCGCCCGGCCGGGCGCCGTCGCTGCCAGCCGGGCCCGGGGGGGCGGCCGGGCCGCCGGGGCGCCCCCACCGCGGAGTGTCGCGCTCGGGA
GGCGGGCAGGGGATGAGGGGGCCGCGGCCGGCGGCGGCGGCGGCGGCCGGGGGCGGGCGGTGAGCGCTGCGGGGCGCTGTTGCTGTGGCT
GAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCGCTCGCGGCCCGCGCTCGCTCCTCT
CCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGGGGCTGTTTTCGCGAGCAGGTGAAA
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGGACGT
GTTCCTCATGATCCGGCGCCACAAGACCACCATCTTCACGGACGCCAAGGAGTCCAGCACGGTGTTCGAACTGAAGCGCATCGTCGAGGG
CATCCTCAAGCGGCCTCCTGACGAGCAGCGGCTGTACAAGGATGACCAACTCTTGGATGATGGCAAGACACTGGGCGAGTGTGGCTTCAC
CAGTCAAACAGCACGGCCACAGGCCCCAGCCACAGTGGGGCTGGCCTTCCGGGCAGATGACACCTTTGAGGCCCTGTGCATCGAGCCGTT
TTCCAGCCCGCCAGAGCTGCCCGATGTGATGAAGCCCCAGGACTCGGGAAGCAGTGCCAATGAACAAGCCGTGCACCTGCATGTCCACTC
CCAGACGATGGCCAAGAGCAGAAACACAAGCTGGAGCCAGTGTCCTGGTTTGACAGCATGTTCAACGAGGGAACCCCAAGACGGACCCAC

>19385_19385_3_CREBBP-TCEB2_CREBBP_chr16_3929832_ENST00000262367_TCEB2_chr16_2827128_ENST00000262306_length(amino acids)=245AA_BP=49
MPAARERSERGPRAGGRAPREREGAGRVGEAAAKSQPQQQRPAALTARPRPPPPPPAAAPSSPARLPSATLRGGGAPAARPPPRARLAAT
APGRAAQAVPENMVPPPPPPRSPPAPHLMNSLAARRRGGSGLRSRPAARRRRRREEKQCAERGRRRRRGPPTPRSAAAAAAAAAAAAGLR

--------------------------------------------------------------
>19385_19385_4_CREBBP-TCEB2_CREBBP_chr16_3929832_ENST00000262367_TCEB2_chr16_2827128_ENST00000409906_length(transcript)=1825nt_BP=895nt
TTCTTTTTTTTTTAATTGAGGAATCAACAGCCGCCATCTTGTCGCGGACCCGACCGGGGCTTCGAGCGCGATCTACTCGGCCCCGCCGGT
CCCGGGCCCCACAACCGCCCGCGCACCCCGCTCCGCCCGGCCGGCCCGCTCCGCCCGGCCCTCGGCGCCCGCCCCGGCGGCCCCGCTCGC
CTCTCGGCTCGGCCTCCCGGAGCCCGGCGGCGGCGGCGGCGGCAGCGGCGGCGGCGGCGGCGGAACGGGGGGTGGGGGGGCCGCGGCGGC
GGCGGCGACCCCGCTCGGCGCATTGTTTTTCCTCACGGCGGCGGCGGCGGCGGGCCGCGGGCCGGGAGCGGAGCCCGGAGCCCCCTCGTC
GTCGGGCCGCGAGCGAATTCATTAAGTGGGGCGCGGGGGGGGAGCGAGGCGGCGGCGGCGGCGGCACCATGTTCTCGGGGACTGCCTGAG
CCGCCCGGCCGGGCGCCGTCGCTGCCAGCCGGGCCCGGGGGGGCGGCCGGGCCGCCGGGGCGCCCCCACCGCGGAGTGTCGCGCTCGGGA
GGCGGGCAGGGGATGAGGGGGCCGCGGCCGGCGGCGGCGGCGGCGGCCGGGGGCGGGCGGTGAGCGCTGCGGGGCGCTGTTGCTGTGGCT
GAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCGCTCGCGGCCCGCGCTCGCTCCTCT
CCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGGGGCTGTTTTCGCGAGCAGGTGAAA
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGGACGT
GTTCCTCATGATCCGGCGCCACAAGACCACCATCTTCACGGACGCCAAGGAGTCCAGCACGGTGTTCGAACTGAAGCGCATCGTCGAGGG
CATCCTCAAGCGGCCTCCTGACGAGCAGCGGCTGTACAAGGATGACCAACTCTTGGATGATGGCAAGACACTGGGCGAGTGTGGCTTCAC
CAGTCAAACAGCACGGCCACAGGCCCCAGCCACAGTGGGGCTGGCCTTCCGGGCAGATGACACCTTTGAGGCCCTGTGCATCGAGCCGTT
TTCCAGCCCGCCAGAGCTGCCCGATGTGATGAAGCCCCAGGACTCGGGAAGCAGTGCCAATGAACAAGCCGTGCAGTGAGGACCCCCAAG
AGGCCCATTTCCCCCAATAAAAGAGATTTGGGAGTCTGCCTGGTTGCTGCCTCTTTTTCCCGCCCCTCCCTGGGATGGGTCCCACTCCCT
GTGGGCTCCTTTTGGGGCTTGTGCTTGGCAGTTCCTGTGCTGTCCTGTCTCCCAGATCCTGAGACCCTGGCTGAGAACTTGGCCCAGCCT
GCTGCTTAAAGGCACCATGGGGACCTGGGTTGCCCTGAGACCCAAGCCATTGTTAGCAGCTAGCCAGCCACACCAACCACGCCAGGGGGA
GGAAAGGGAAGGACTGGGAGAGACACAAAGACCAGAGCCAGCCTCAGGGACAAGAGATTCCAGTTTTAGGCCTTTCTCCTTCTAAGTGCC
CCCCACCCCCATAGCCTGCATGTCCACTCCCAGACGATGGCCAAGAGCAGAAACACAAGCTGGAGCCAGTGTCCTGGTTTGACAGCATGT
TCAACGAGGGAACCCCAAGACGGACCCACACAGGTCCACCCACGCTGGGGGCTGTAATCACGGAGGGAAGTGGCTGCCCCCTTAACACAC

>19385_19385_4_CREBBP-TCEB2_CREBBP_chr16_3929832_ENST00000262367_TCEB2_chr16_2827128_ENST00000409906_length(amino acids)=245AA_BP=49
MPAARERSERGPRAGGRAPREREGAGRVGEAAAKSQPQQQRPAALTARPRPPPPPPAAAPSSPARLPSATLRGGGAPAARPPPRARLAAT
APGRAAQAVPENMVPPPPPPRSPPAPHLMNSLAARRRGGSGLRSRPAARRRRRREEKQCAERGRRRRRGPPTPRSAAAAAAAAAAAAGLR

--------------------------------------------------------------
>19385_19385_5_CREBBP-TCEB2_CREBBP_chr16_3929832_ENST00000382070_TCEB2_chr16_2827127_ENST00000262306_length(transcript)=830nt_BP=289nt
CTGCGGGGCGCTGTTGCTGTGGCTGAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCG
CTCGCGGCCCGCGCTCGCTCCTCTCCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGG
GGCTGTTTTCGCGAGCAGGTGAAAATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTC
TCGGCGAATGACAGCACAGGACGTGTTCCTCATGATCCGGCGCCACAAGACCACCATCTTCACGGACGCCAAGGAGTCCAGCACGGTGTT
CGAACTGAAGCGCATCGTCGAGGGCATCCTCAAGCGGCCTCCTGACGAGCAGCGGCTGTACAAGGATGACCAACTCTTGGATGATGGCAA
GACACTGGGCGAGTGTGGCTTCACCAGTCAAACAGCACGGCCACAGGCCCCAGCCACAGTGGGGCTGGCCTTCCGGGCAGATGACACCTT
TGAGGCCCTGTGCATCGAGCCGTTTTCCAGCCCGCCAGAGCTGCCCGATGTGATGAAGCCCCAGGACTCGGGAAGCAGTGCCAATGAACA
AGCCGTGCACCTGCATGTCCACTCCCAGACGATGGCCAAGAGCAGAAACACAAGCTGGAGCCAGTGTCCTGGTTTGACAGCATGTTCAAC
GAGGGAACCCCAAGACGGACCCACACAGGTCCACCCACGCTGGGGGCTGTAATCACGGAGGGAAGTGGCTGCCCCCTTAACACACCTTTA

>19385_19385_5_CREBBP-TCEB2_CREBBP_chr16_3929832_ENST00000382070_TCEB2_chr16_2827127_ENST00000262306_length(amino acids)=187AA_BP=26
MRTCWTDRPTPKEPNSARPVSRRMTAQDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPDEQRLYKDDQLLDDGKTLGECGFTS
QTARPQAPATVGLAFRADDTFEALCIEPFSSPPELPDVMKPQDSGSSANEQAVHLHVHSQTMAKSRNTSWSQCPGLTACSTREPQDGPTQ

--------------------------------------------------------------
>19385_19385_6_CREBBP-TCEB2_CREBBP_chr16_3929832_ENST00000382070_TCEB2_chr16_2827127_ENST00000409906_length(transcript)=1219nt_BP=289nt
CTGCGGGGCGCTGTTGCTGTGGCTGAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCG
CTCGCGGCCCGCGCTCGCTCCTCTCCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGG
GGCTGTTTTCGCGAGCAGGTGAAAATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTC
TCGGCGAATGACAGCACAGGACGTGTTCCTCATGATCCGGCGCCACAAGACCACCATCTTCACGGACGCCAAGGAGTCCAGCACGGTGTT
CGAACTGAAGCGCATCGTCGAGGGCATCCTCAAGCGGCCTCCTGACGAGCAGCGGCTGTACAAGGATGACCAACTCTTGGATGATGGCAA
GACACTGGGCGAGTGTGGCTTCACCAGTCAAACAGCACGGCCACAGGCCCCAGCCACAGTGGGGCTGGCCTTCCGGGCAGATGACACCTT
TGAGGCCCTGTGCATCGAGCCGTTTTCCAGCCCGCCAGAGCTGCCCGATGTGATGAAGCCCCAGGACTCGGGAAGCAGTGCCAATGAACA
AGCCGTGCAGTGAGGACCCCCAAGAGGCCCATTTCCCCCAATAAAAGAGATTTGGGAGTCTGCCTGGTTGCTGCCTCTTTTTCCCGCCCC
TCCCTGGGATGGGTCCCACTCCCTGTGGGCTCCTTTTGGGGCTTGTGCTTGGCAGTTCCTGTGCTGTCCTGTCTCCCAGATCCTGAGACC
CTGGCTGAGAACTTGGCCCAGCCTGCTGCTTAAAGGCACCATGGGGACCTGGGTTGCCCTGAGACCCAAGCCATTGTTAGCAGCTAGCCA
GCCACACCAACCACGCCAGGGGGAGGAAAGGGAAGGACTGGGAGAGACACAAAGACCAGAGCCAGCCTCAGGGACAAGAGATTCCAGTTT
TAGGCCTTTCTCCTTCTAAGTGCCCCCCACCCCCATAGCCTGCATGTCCACTCCCAGACGATGGCCAAGAGCAGAAACACAAGCTGGAGC
CAGTGTCCTGGTTTGACAGCATGTTCAACGAGGGAACCCCAAGACGGACCCACACAGGTCCACCCACGCTGGGGGCTGTAATCACGGAGG

>19385_19385_6_CREBBP-TCEB2_CREBBP_chr16_3929832_ENST00000382070_TCEB2_chr16_2827127_ENST00000409906_length(amino acids)=181AA_BP=1
MGDRTAQELPSTSPKRSPQGVGPIPGRGGKKRQQPGRLPNLFYWGKWASWGSSLHGLFIGTASRVLGLHHIGQLWRAGKRLDAQGLKGVI
CPEGQPHCGWGLWPCCLTGEATLAQCLAIIQELVILVQPLLVRRPLEDALDDALQFEHRAGLLGVREDGGLVAPDHEEHVLCCHSPRNRA

--------------------------------------------------------------
>19385_19385_7_CREBBP-TCEB2_CREBBP_chr16_3929832_ENST00000382070_TCEB2_chr16_2827128_ENST00000262306_length(transcript)=830nt_BP=289nt
CTGCGGGGCGCTGTTGCTGTGGCTGAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCG
CTCGCGGCCCGCGCTCGCTCCTCTCCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGG
GGCTGTTTTCGCGAGCAGGTGAAAATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTC
TCGGCGAATGACAGCACAGGACGTGTTCCTCATGATCCGGCGCCACAAGACCACCATCTTCACGGACGCCAAGGAGTCCAGCACGGTGTT
CGAACTGAAGCGCATCGTCGAGGGCATCCTCAAGCGGCCTCCTGACGAGCAGCGGCTGTACAAGGATGACCAACTCTTGGATGATGGCAA
GACACTGGGCGAGTGTGGCTTCACCAGTCAAACAGCACGGCCACAGGCCCCAGCCACAGTGGGGCTGGCCTTCCGGGCAGATGACACCTT
TGAGGCCCTGTGCATCGAGCCGTTTTCCAGCCCGCCAGAGCTGCCCGATGTGATGAAGCCCCAGGACTCGGGAAGCAGTGCCAATGAACA
AGCCGTGCACCTGCATGTCCACTCCCAGACGATGGCCAAGAGCAGAAACACAAGCTGGAGCCAGTGTCCTGGTTTGACAGCATGTTCAAC
GAGGGAACCCCAAGACGGACCCACACAGGTCCACCCACGCTGGGGGCTGTAATCACGGAGGGAAGTGGCTGCCCCCTTAACACACCTTTA

>19385_19385_7_CREBBP-TCEB2_CREBBP_chr16_3929832_ENST00000382070_TCEB2_chr16_2827128_ENST00000262306_length(amino acids)=187AA_BP=26
MRTCWTDRPTPKEPNSARPVSRRMTAQDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPDEQRLYKDDQLLDDGKTLGECGFTS
QTARPQAPATVGLAFRADDTFEALCIEPFSSPPELPDVMKPQDSGSSANEQAVHLHVHSQTMAKSRNTSWSQCPGLTACSTREPQDGPTQ

--------------------------------------------------------------
>19385_19385_8_CREBBP-TCEB2_CREBBP_chr16_3929832_ENST00000382070_TCEB2_chr16_2827128_ENST00000409906_length(transcript)=1219nt_BP=289nt
CTGCGGGGCGCTGTTGCTGTGGCTGAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCG
CTCGCGGCCCGCGCTCGCTCCTCTCCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGG
GGCTGTTTTCGCGAGCAGGTGAAAATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTC
TCGGCGAATGACAGCACAGGACGTGTTCCTCATGATCCGGCGCCACAAGACCACCATCTTCACGGACGCCAAGGAGTCCAGCACGGTGTT
CGAACTGAAGCGCATCGTCGAGGGCATCCTCAAGCGGCCTCCTGACGAGCAGCGGCTGTACAAGGATGACCAACTCTTGGATGATGGCAA
GACACTGGGCGAGTGTGGCTTCACCAGTCAAACAGCACGGCCACAGGCCCCAGCCACAGTGGGGCTGGCCTTCCGGGCAGATGACACCTT
TGAGGCCCTGTGCATCGAGCCGTTTTCCAGCCCGCCAGAGCTGCCCGATGTGATGAAGCCCCAGGACTCGGGAAGCAGTGCCAATGAACA
AGCCGTGCAGTGAGGACCCCCAAGAGGCCCATTTCCCCCAATAAAAGAGATTTGGGAGTCTGCCTGGTTGCTGCCTCTTTTTCCCGCCCC
TCCCTGGGATGGGTCCCACTCCCTGTGGGCTCCTTTTGGGGCTTGTGCTTGGCAGTTCCTGTGCTGTCCTGTCTCCCAGATCCTGAGACC
CTGGCTGAGAACTTGGCCCAGCCTGCTGCTTAAAGGCACCATGGGGACCTGGGTTGCCCTGAGACCCAAGCCATTGTTAGCAGCTAGCCA
GCCACACCAACCACGCCAGGGGGAGGAAAGGGAAGGACTGGGAGAGACACAAAGACCAGAGCCAGCCTCAGGGACAAGAGATTCCAGTTT
TAGGCCTTTCTCCTTCTAAGTGCCCCCCACCCCCATAGCCTGCATGTCCACTCCCAGACGATGGCCAAGAGCAGAAACACAAGCTGGAGC
CAGTGTCCTGGTTTGACAGCATGTTCAACGAGGGAACCCCAAGACGGACCCACACAGGTCCACCCACGCTGGGGGCTGTAATCACGGAGG

>19385_19385_8_CREBBP-TCEB2_CREBBP_chr16_3929832_ENST00000382070_TCEB2_chr16_2827128_ENST00000409906_length(amino acids)=181AA_BP=1
MGDRTAQELPSTSPKRSPQGVGPIPGRGGKKRQQPGRLPNLFYWGKWASWGSSLHGLFIGTASRVLGLHHIGQLWRAGKRLDAQGLKGVI
CPEGQPHCGWGLWPCCLTGEATLAQCLAIIQELVILVQPLLVRRPLEDALDDALQFEHRAGLLGVREDGGLVAPDHEEHVLCCHSPRNRA

--------------------------------------------------------------
>19385_19385_9_CREBBP-TCEB2_CREBBP_chr16_3929833_ENST00000262367_TCEB2_chr16_2827128_ENST00000262306_length(transcript)=1436nt_BP=895nt
TTCTTTTTTTTTTAATTGAGGAATCAACAGCCGCCATCTTGTCGCGGACCCGACCGGGGCTTCGAGCGCGATCTACTCGGCCCCGCCGGT
CCCGGGCCCCACAACCGCCCGCGCACCCCGCTCCGCCCGGCCGGCCCGCTCCGCCCGGCCCTCGGCGCCCGCCCCGGCGGCCCCGCTCGC
CTCTCGGCTCGGCCTCCCGGAGCCCGGCGGCGGCGGCGGCGGCAGCGGCGGCGGCGGCGGCGGAACGGGGGGTGGGGGGGCCGCGGCGGC
GGCGGCGACCCCGCTCGGCGCATTGTTTTTCCTCACGGCGGCGGCGGCGGCGGGCCGCGGGCCGGGAGCGGAGCCCGGAGCCCCCTCGTC
GTCGGGCCGCGAGCGAATTCATTAAGTGGGGCGCGGGGGGGGAGCGAGGCGGCGGCGGCGGCGGCACCATGTTCTCGGGGACTGCCTGAG
CCGCCCGGCCGGGCGCCGTCGCTGCCAGCCGGGCCCGGGGGGGCGGCCGGGCCGCCGGGGCGCCCCCACCGCGGAGTGTCGCGCTCGGGA
GGCGGGCAGGGGATGAGGGGGCCGCGGCCGGCGGCGGCGGCGGCGGCCGGGGGCGGGCGGTGAGCGCTGCGGGGCGCTGTTGCTGTGGCT
GAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCGCTCGCGGCCCGCGCTCGCTCCTCT
CCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGGGGCTGTTTTCGCGAGCAGGTGAAA
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGGACGT
GTTCCTCATGATCCGGCGCCACAAGACCACCATCTTCACGGACGCCAAGGAGTCCAGCACGGTGTTCGAACTGAAGCGCATCGTCGAGGG
CATCCTCAAGCGGCCTCCTGACGAGCAGCGGCTGTACAAGGATGACCAACTCTTGGATGATGGCAAGACACTGGGCGAGTGTGGCTTCAC
CAGTCAAACAGCACGGCCACAGGCCCCAGCCACAGTGGGGCTGGCCTTCCGGGCAGATGACACCTTTGAGGCCCTGTGCATCGAGCCGTT
TTCCAGCCCGCCAGAGCTGCCCGATGTGATGAAGCCCCAGGACTCGGGAAGCAGTGCCAATGAACAAGCCGTGCACCTGCATGTCCACTC
CCAGACGATGGCCAAGAGCAGAAACACAAGCTGGAGCCAGTGTCCTGGTTTGACAGCATGTTCAACGAGGGAACCCCAAGACGGACCCAC

>19385_19385_9_CREBBP-TCEB2_CREBBP_chr16_3929833_ENST00000262367_TCEB2_chr16_2827128_ENST00000262306_length(amino acids)=245AA_BP=49
MPAARERSERGPRAGGRAPREREGAGRVGEAAAKSQPQQQRPAALTARPRPPPPPPAAAPSSPARLPSATLRGGGAPAARPPPRARLAAT
APGRAAQAVPENMVPPPPPPRSPPAPHLMNSLAARRRGGSGLRSRPAARRRRRREEKQCAERGRRRRRGPPTPRSAAAAAAAAAAAAGLR

--------------------------------------------------------------
>19385_19385_10_CREBBP-TCEB2_CREBBP_chr16_3929833_ENST00000262367_TCEB2_chr16_2827128_ENST00000409906_length(transcript)=1825nt_BP=895nt
TTCTTTTTTTTTTAATTGAGGAATCAACAGCCGCCATCTTGTCGCGGACCCGACCGGGGCTTCGAGCGCGATCTACTCGGCCCCGCCGGT
CCCGGGCCCCACAACCGCCCGCGCACCCCGCTCCGCCCGGCCGGCCCGCTCCGCCCGGCCCTCGGCGCCCGCCCCGGCGGCCCCGCTCGC
CTCTCGGCTCGGCCTCCCGGAGCCCGGCGGCGGCGGCGGCGGCAGCGGCGGCGGCGGCGGCGGAACGGGGGGTGGGGGGGCCGCGGCGGC
GGCGGCGACCCCGCTCGGCGCATTGTTTTTCCTCACGGCGGCGGCGGCGGCGGGCCGCGGGCCGGGAGCGGAGCCCGGAGCCCCCTCGTC
GTCGGGCCGCGAGCGAATTCATTAAGTGGGGCGCGGGGGGGGAGCGAGGCGGCGGCGGCGGCGGCACCATGTTCTCGGGGACTGCCTGAG
CCGCCCGGCCGGGCGCCGTCGCTGCCAGCCGGGCCCGGGGGGGCGGCCGGGCCGCCGGGGCGCCCCCACCGCGGAGTGTCGCGCTCGGGA
GGCGGGCAGGGGATGAGGGGGCCGCGGCCGGCGGCGGCGGCGGCGGCCGGGGGCGGGCGGTGAGCGCTGCGGGGCGCTGTTGCTGTGGCT
GAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCGCTCGCGGCCCGCGCTCGCTCCTCT
CCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGGGGCTGTTTTCGCGAGCAGGTGAAA
ATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTCTCGGCGAATGACAGCACAGGACGT
GTTCCTCATGATCCGGCGCCACAAGACCACCATCTTCACGGACGCCAAGGAGTCCAGCACGGTGTTCGAACTGAAGCGCATCGTCGAGGG
CATCCTCAAGCGGCCTCCTGACGAGCAGCGGCTGTACAAGGATGACCAACTCTTGGATGATGGCAAGACACTGGGCGAGTGTGGCTTCAC
CAGTCAAACAGCACGGCCACAGGCCCCAGCCACAGTGGGGCTGGCCTTCCGGGCAGATGACACCTTTGAGGCCCTGTGCATCGAGCCGTT
TTCCAGCCCGCCAGAGCTGCCCGATGTGATGAAGCCCCAGGACTCGGGAAGCAGTGCCAATGAACAAGCCGTGCAGTGAGGACCCCCAAG
AGGCCCATTTCCCCCAATAAAAGAGATTTGGGAGTCTGCCTGGTTGCTGCCTCTTTTTCCCGCCCCTCCCTGGGATGGGTCCCACTCCCT
GTGGGCTCCTTTTGGGGCTTGTGCTTGGCAGTTCCTGTGCTGTCCTGTCTCCCAGATCCTGAGACCCTGGCTGAGAACTTGGCCCAGCCT
GCTGCTTAAAGGCACCATGGGGACCTGGGTTGCCCTGAGACCCAAGCCATTGTTAGCAGCTAGCCAGCCACACCAACCACGCCAGGGGGA
GGAAAGGGAAGGACTGGGAGAGACACAAAGACCAGAGCCAGCCTCAGGGACAAGAGATTCCAGTTTTAGGCCTTTCTCCTTCTAAGTGCC
CCCCACCCCCATAGCCTGCATGTCCACTCCCAGACGATGGCCAAGAGCAGAAACACAAGCTGGAGCCAGTGTCCTGGTTTGACAGCATGT
TCAACGAGGGAACCCCAAGACGGACCCACACAGGTCCACCCACGCTGGGGGCTGTAATCACGGAGGGAAGTGGCTGCCCCCTTAACACAC

>19385_19385_10_CREBBP-TCEB2_CREBBP_chr16_3929833_ENST00000262367_TCEB2_chr16_2827128_ENST00000409906_length(amino acids)=245AA_BP=49
MPAARERSERGPRAGGRAPREREGAGRVGEAAAKSQPQQQRPAALTARPRPPPPPPAAAPSSPARLPSATLRGGGAPAARPPPRARLAAT
APGRAAQAVPENMVPPPPPPRSPPAPHLMNSLAARRRGGSGLRSRPAARRRRRREEKQCAERGRRRRRGPPTPRSAAAAAAAAAAAAGLR

--------------------------------------------------------------
>19385_19385_11_CREBBP-TCEB2_CREBBP_chr16_3929833_ENST00000382070_TCEB2_chr16_2827128_ENST00000262306_length(transcript)=830nt_BP=289nt
CTGCGGGGCGCTGTTGCTGTGGCTGAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCG
CTCGCGGCCCGCGCTCGCTCCTCTCCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGG
GGCTGTTTTCGCGAGCAGGTGAAAATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTC
TCGGCGAATGACAGCACAGGACGTGTTCCTCATGATCCGGCGCCACAAGACCACCATCTTCACGGACGCCAAGGAGTCCAGCACGGTGTT
CGAACTGAAGCGCATCGTCGAGGGCATCCTCAAGCGGCCTCCTGACGAGCAGCGGCTGTACAAGGATGACCAACTCTTGGATGATGGCAA
GACACTGGGCGAGTGTGGCTTCACCAGTCAAACAGCACGGCCACAGGCCCCAGCCACAGTGGGGCTGGCCTTCCGGGCAGATGACACCTT
TGAGGCCCTGTGCATCGAGCCGTTTTCCAGCCCGCCAGAGCTGCCCGATGTGATGAAGCCCCAGGACTCGGGAAGCAGTGCCAATGAACA
AGCCGTGCACCTGCATGTCCACTCCCAGACGATGGCCAAGAGCAGAAACACAAGCTGGAGCCAGTGTCCTGGTTTGACAGCATGTTCAAC
GAGGGAACCCCAAGACGGACCCACACAGGTCCACCCACGCTGGGGGCTGTAATCACGGAGGGAAGTGGCTGCCCCCTTAACACACCTTTA

>19385_19385_11_CREBBP-TCEB2_CREBBP_chr16_3929833_ENST00000382070_TCEB2_chr16_2827128_ENST00000262306_length(amino acids)=187AA_BP=26
MRTCWTDRPTPKEPNSARPVSRRMTAQDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPDEQRLYKDDQLLDDGKTLGECGFTS
QTARPQAPATVGLAFRADDTFEALCIEPFSSPPELPDVMKPQDSGSSANEQAVHLHVHSQTMAKSRNTSWSQCPGLTACSTREPQDGPTQ

--------------------------------------------------------------
>19385_19385_12_CREBBP-TCEB2_CREBBP_chr16_3929833_ENST00000382070_TCEB2_chr16_2827128_ENST00000409906_length(transcript)=1219nt_BP=289nt
CTGCGGGGCGCTGTTGCTGTGGCTGAGATTTGGCCGCCGCCTCCCCCACCCGGCCTGCGCCCTCCCTCTCCCTCGGCGCCCGCCCGCCCG
CTCGCGGCCCGCGCTCGCTCCTCTCCCTCGCAGCCGGCAGGGCCCCCGACCCCCGTCCGGGCCCTCGCCGGCCCGGCCGCCCGTGCCCGG
GGCTGTTTTCGCGAGCAGGTGAAAATGGCTGAGAACTTGCTGGACGGACCGCCCAACCCCAAAAGAGCCAAACTCAGCTCGCCCGGTTTC
TCGGCGAATGACAGCACAGGACGTGTTCCTCATGATCCGGCGCCACAAGACCACCATCTTCACGGACGCCAAGGAGTCCAGCACGGTGTT
CGAACTGAAGCGCATCGTCGAGGGCATCCTCAAGCGGCCTCCTGACGAGCAGCGGCTGTACAAGGATGACCAACTCTTGGATGATGGCAA
GACACTGGGCGAGTGTGGCTTCACCAGTCAAACAGCACGGCCACAGGCCCCAGCCACAGTGGGGCTGGCCTTCCGGGCAGATGACACCTT
TGAGGCCCTGTGCATCGAGCCGTTTTCCAGCCCGCCAGAGCTGCCCGATGTGATGAAGCCCCAGGACTCGGGAAGCAGTGCCAATGAACA
AGCCGTGCAGTGAGGACCCCCAAGAGGCCCATTTCCCCCAATAAAAGAGATTTGGGAGTCTGCCTGGTTGCTGCCTCTTTTTCCCGCCCC
TCCCTGGGATGGGTCCCACTCCCTGTGGGCTCCTTTTGGGGCTTGTGCTTGGCAGTTCCTGTGCTGTCCTGTCTCCCAGATCCTGAGACC
CTGGCTGAGAACTTGGCCCAGCCTGCTGCTTAAAGGCACCATGGGGACCTGGGTTGCCCTGAGACCCAAGCCATTGTTAGCAGCTAGCCA
GCCACACCAACCACGCCAGGGGGAGGAAAGGGAAGGACTGGGAGAGACACAAAGACCAGAGCCAGCCTCAGGGACAAGAGATTCCAGTTT
TAGGCCTTTCTCCTTCTAAGTGCCCCCCACCCCCATAGCCTGCATGTCCACTCCCAGACGATGGCCAAGAGCAGAAACACAAGCTGGAGC
CAGTGTCCTGGTTTGACAGCATGTTCAACGAGGGAACCCCAAGACGGACCCACACAGGTCCACCCACGCTGGGGGCTGTAATCACGGAGG

>19385_19385_12_CREBBP-TCEB2_CREBBP_chr16_3929833_ENST00000382070_TCEB2_chr16_2827128_ENST00000409906_length(amino acids)=181AA_BP=1
MGDRTAQELPSTSPKRSPQGVGPIPGRGGKKRQQPGRLPNLFYWGKWASWGSSLHGLFIGTASRVLGLHHIGQLWRAGKRLDAQGLKGVI
CPEGQPHCGWGLWPCCLTGEATLAQCLAIIQELVILVQPLLVRRPLEDALDDALQFEHRAGLLGVREDGGLVAPDHEEHVLCCHSPRNRA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CREBBP-TCEB2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-1311162_118028.3333333333333322443.0ASF1A
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-1301162_118028.3333333333333322405.0ASF1A
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-1311162_118028.3333333333333322443.0ASF1A
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-1301162_118028.3333333333333322405.0ASF1A
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-1311162_118028.3333333333333322443.0ASF1A
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-1301162_118028.3333333333333322405.0ASF1A
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-1311433_143528.3333333333333322443.0histone
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-1301433_143528.3333333333333322405.0histone
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-1311433_143528.3333333333333322443.0histone
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-1301433_143528.3333333333333322405.0histone
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-1311433_143528.3333333333333322443.0histone
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-1301433_143528.3333333333333322405.0histone
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-1311124_117028.3333333333333322443.0histone
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-1301124_117028.3333333333333322405.0histone
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-1311124_117028.3333333333333322443.0histone
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-1301124_117028.3333333333333322405.0histone
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-1311124_117028.3333333333333322443.0histone
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-1301124_117028.3333333333333322405.0histone
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-131227_41028.3333333333333322443.0SRCAP
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-130227_41028.3333333333333322405.0SRCAP
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-131227_41028.3333333333333322443.0SRCAP
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-130227_41028.3333333333333322405.0SRCAP
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-131227_41028.3333333333333322443.0SRCAP
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-130227_41028.3333333333333322405.0SRCAP
HgeneCREBBPchr16:3929832chr16:2827127ENST00000262367-1311460_189128.3333333333333322443.0TRERF1
HgeneCREBBPchr16:3929832chr16:2827127ENST00000382070-1301460_189128.3333333333333322405.0TRERF1
HgeneCREBBPchr16:3929832chr16:2827128ENST00000262367-1311460_189128.3333333333333322443.0TRERF1
HgeneCREBBPchr16:3929832chr16:2827128ENST00000382070-1301460_189128.3333333333333322405.0TRERF1
HgeneCREBBPchr16:3929833chr16:2827128ENST00000262367-1311460_189128.3333333333333322443.0TRERF1
HgeneCREBBPchr16:3929833chr16:2827128ENST00000382070-1301460_189128.3333333333333322405.0TRERF1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CREBBP-TCEB2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CREBBP-TCEB2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource