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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CSMD3-ADCY8 (FusionGDB2 ID:19777)

Fusion Gene Summary for CSMD3-ADCY8

check button Fusion gene summary
Fusion gene informationFusion gene name: CSMD3-ADCY8
Fusion gene ID: 19777
HgeneTgene
Gene symbol

CSMD3

ADCY8

Gene ID

114788

114

Gene nameCUB and Sushi multiple domains 3adenylate cyclase 8
Synonyms-AC8|ADCY3|HBAC1
Cytomap

8q23.3

8q24.22

Type of geneprotein-codingprotein-coding
DescriptionCUB and sushi domain-containing protein 3CUB and sushi multiple domains protein 3adenylate cyclase type 8ATP pyrophosphate-lyase 8HEL-S-172mPadenylate cyclase 8 (brain)adenylate cyclase type VIIIadenylyl cyclase 8adenylyl cyclase-8, brainca(2+)/calmodulin-activated adenylyl cyclaseepididymis secretory sperm binding protein Li
Modification date2020031320200313
UniProtAcc

Q7Z407

P40145

Ensembl transtripts involved in fusion geneENST00000297405, ENST00000352409, 
ENST00000455883, ENST00000343508, 
ENST00000519485, 		ENST00000286355, 
ENST00000377928, 
Fusion gene scores* DoF score7 X 7 X 3=1473 X 3 X 3=27
# samples 73
** MAII scorelog2(7/147*10)=-1.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: CSMD3 [Title/Abstract] AND ADCY8 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCSMD3(114290821)-ADCY8(131964244), # samples:2
Anticipated loss of major functional domain due to fusion event.CSMD3-ADCY8 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
CSMD3-ADCY8 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CSMD3-ADCY8 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
CSMD3-ADCY8 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CSMD3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ADCY8 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A3M1-01ACSMD3chr8

114290821

-ADCY8chr8

131964244

-


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Fusion Gene ORF analysis for CSMD3-ADCY8

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000297405ENST00000286355CSMD3chr8

114290821

-ADCY8chr8

131964244

-
Frame-shiftENST00000297405ENST00000377928CSMD3chr8

114290821

-ADCY8chr8

131964244

-
Frame-shiftENST00000352409ENST00000286355CSMD3chr8

114290821

-ADCY8chr8

131964244

-
Frame-shiftENST00000352409ENST00000377928CSMD3chr8

114290821

-ADCY8chr8

131964244

-
Frame-shiftENST00000455883ENST00000286355CSMD3chr8

114290821

-ADCY8chr8

131964244

-
Frame-shiftENST00000455883ENST00000377928CSMD3chr8

114290821

-ADCY8chr8

131964244

-
In-frameENST00000343508ENST00000286355CSMD3chr8

114290821

-ADCY8chr8

131964244

-
In-frameENST00000343508ENST00000377928CSMD3chr8

114290821

-ADCY8chr8

131964244

-
intron-3CDSENST00000519485ENST00000286355CSMD3chr8

114290821

-ADCY8chr8

131964244

-
intron-3CDSENST00000519485ENST00000377928CSMD3chr8

114290821

-ADCY8chr8

131964244

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000343508CSMD3chr8114290821-ENST00000286355ADCY8chr8131964244-33005655263210894
ENST00000343508CSMD3chr8114290821-ENST00000377928ADCY8chr8131964244-28185655262817764

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000343508ENST00000286355CSMD3chr8114290821-ADCY8chr8131964244-0.0008752010.9991248
ENST00000343508ENST00000377928CSMD3chr8114290821-ADCY8chr8131964244-0.0019320390.99806803

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Fusion Genomic Features for CSMD3-ADCY8


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CSMD3-ADCY8


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:114290821/chr8:131964244)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CSMD3

Q7Z407

ADCY8

P40145

FUNCTION: Involved in dendrite development. {ECO:0000250|UniProtKB:Q80T79}.FUNCTION: Catalyzes the formation of cAMP in response to calcium entry leadings to cAMP signaling activation that affect processes suche as synaptic plasticity and insulin secretion. Plays a role in many brain functions, such as learning, memory, drug addiction, and anxiety modulation through regulation of synaptic plasticity by modulating long-term memory and long-term potentiation (LTP) through CREB transcription factor activity modulation. Plays a central role in insulin secretion by controlling glucose homeostasis through glucagon-like peptide 1 and glucose signaling pathway and maintains insulin secretion through calcium-dependent PKA activation leading to vesicle pool replenishment. Also, allows PTGER3 to induce potentiation of PTGER4-mediated PLA2 secretion by switching from a negative to a positive regulation, during the IL1B induced-dedifferentiation of smooth muscle cells. {ECO:0000250|UniProtKB:P40146}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-37165_1731713708.0DomainCUB 1
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-36965_1731713638.0DomainCUB 1
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-36965_1731713539.0DomainCUB 1
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3711_421713708.0Topological domainCytoplasmic
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4721_421313668.0Topological domainCytoplasmic
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3691_421713638.0Topological domainCytoplasmic
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3691_421713539.0Topological domainCytoplasmic
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-37143_631713708.0TransmembraneHelical
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-47243_631313668.0TransmembraneHelical
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-36943_631713638.0TransmembraneHelical
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-36943_631713539.0TransmembraneHelical
TgeneADCY8chr8:114290821chr8:131964244ENST000002863551181109_11113701252.0Nucleotide bindingATP
TgeneADCY8chr8:114290821chr8:131964244ENST000002863551181116_11203701252.0Nucleotide bindingATP
TgeneADCY8chr8:114290821chr8:131964244ENST00000286355118419_4243701252.0Nucleotide bindingATP
TgeneADCY8chr8:114290821chr8:131964244ENST00000286355118461_4633701252.0Nucleotide bindingATP
TgeneADCY8chr8:114290821chr8:131964244ENST000002863551181200_12153701252.0RegionRequired for both calcium stimulation and maintenance of autoinhibition
TgeneADCY8chr8:114290821chr8:131964244ENST00000286355118915_12513701252.0Topological domainCytoplasmic
TgeneADCY8chr8:114290821chr8:131964244ENST00000286355118716_7363701252.0TransmembraneHelical
TgeneADCY8chr8:114290821chr8:131964244ENST00000286355118738_7583701252.0TransmembraneHelical
TgeneADCY8chr8:114290821chr8:131964244ENST00000286355118787_8073701252.0TransmembraneHelical
TgeneADCY8chr8:114290821chr8:131964244ENST00000286355118831_8513701252.0TransmembraneHelical
TgeneADCY8chr8:114290821chr8:131964244ENST00000286355118861_8813701252.0TransmembraneHelical
TgeneADCY8chr8:114290821chr8:131964244ENST00000286355118894_9143701252.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3711008_10651713708.0DomainSushi 5
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3711067_11771713708.0DomainCUB 6
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3711180_12391713708.0DomainSushi 6
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3711241_13491713708.0DomainCUB 7
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3711352_14121713708.0DomainSushi 7
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3711414_15231713708.0DomainCUB 8
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3711526_15861713708.0DomainSushi 8
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3711588_16961713708.0DomainCUB 9
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3711699_17601713708.0DomainSushi 9
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3711762_18701713708.0DomainCUB 10
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-371176_2371713708.0DomainSushi 1
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3711876_19371713708.0DomainSushi 10
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3711939_20471713708.0DomainCUB 11
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3712050_21091713708.0DomainSushi 11
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3712111_22191713708.0DomainCUB 12
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3712222_22811713708.0DomainSushi 12
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3712283_23941713708.0DomainCUB 13
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3712393_24541713708.0DomainSushi 13
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-371241_3451713708.0DomainCUB 2
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3712456_25671713708.0DomainCUB 14
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3712567_26291713708.0DomainSushi 14
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3712630_26911713708.0DomainSushi 15
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3712757_28141713708.0DomainSushi 17
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3712815_28721713708.0DomainSushi 18
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3712873_29301713708.0DomainSushi 19
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3712931_29921713708.0DomainSushi 20
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3712993_30501713708.0DomainSushi 21
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3713054_31111713708.0DomainSushi 22
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3713112_31701713708.0DomainSushi 23
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3713171_32301713708.0DomainSushi 24
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3713231_32881713708.0DomainSushi 25
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3713289_33461713708.0DomainSushi 26
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3713350_34081713708.0DomainSushi 27
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3713409_34681713708.0DomainSushi 28
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-371484_5451713708.0DomainSushi 2
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-371548_6591713708.0DomainCUB 3
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-371662_7191713708.0DomainSushi 3
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-371721_8291713708.0DomainCUB 4
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-371832_8931713708.0DomainSushi 4
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-371895_10031713708.0DomainCUB 5
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4721008_10651313668.0DomainSushi 5
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4721067_11771313668.0DomainCUB 6
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4721180_12391313668.0DomainSushi 6
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4721241_13491313668.0DomainCUB 7
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4721352_14121313668.0DomainSushi 7
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4721414_15231313668.0DomainCUB 8
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4721526_15861313668.0DomainSushi 8
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4721588_16961313668.0DomainCUB 9
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4721699_17601313668.0DomainSushi 9
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4721762_18701313668.0DomainCUB 10
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-472176_2371313668.0DomainSushi 1
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4721876_19371313668.0DomainSushi 10
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4721939_20471313668.0DomainCUB 11
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4722050_21091313668.0DomainSushi 11
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4722111_22191313668.0DomainCUB 12
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4722222_22811313668.0DomainSushi 12
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4722283_23941313668.0DomainCUB 13
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4722393_24541313668.0DomainSushi 13
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-472241_3451313668.0DomainCUB 2
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4722456_25671313668.0DomainCUB 14
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4722567_26291313668.0DomainSushi 14
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4722630_26911313668.0DomainSushi 15
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4722757_28141313668.0DomainSushi 17
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4722815_28721313668.0DomainSushi 18
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4722873_29301313668.0DomainSushi 19
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4722931_29921313668.0DomainSushi 20
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4722993_30501313668.0DomainSushi 21
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4723054_31111313668.0DomainSushi 22
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4723112_31701313668.0DomainSushi 23
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4723171_32301313668.0DomainSushi 24
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4723231_32881313668.0DomainSushi 25
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4723289_33461313668.0DomainSushi 26
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4723350_34081313668.0DomainSushi 27
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4723409_34681313668.0DomainSushi 28
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-472484_5451313668.0DomainSushi 2
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-472548_6591313668.0DomainCUB 3
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-47265_1731313668.0DomainCUB 1
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-472662_7191313668.0DomainSushi 3
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-472721_8291313668.0DomainCUB 4
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-472832_8931313668.0DomainSushi 4
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-472895_10031313668.0DomainCUB 5
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3691008_10651713638.0DomainSushi 5
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3691067_11771713638.0DomainCUB 6
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3691180_12391713638.0DomainSushi 6
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3691241_13491713638.0DomainCUB 7
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3691352_14121713638.0DomainSushi 7
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3691414_15231713638.0DomainCUB 8
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3691526_15861713638.0DomainSushi 8
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3691588_16961713638.0DomainCUB 9
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3691699_17601713638.0DomainSushi 9
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3691762_18701713638.0DomainCUB 10
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-369176_2371713638.0DomainSushi 1
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3691876_19371713638.0DomainSushi 10
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3691939_20471713638.0DomainCUB 11
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3692050_21091713638.0DomainSushi 11
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3692111_22191713638.0DomainCUB 12
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3692222_22811713638.0DomainSushi 12
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3692283_23941713638.0DomainCUB 13
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3692393_24541713638.0DomainSushi 13
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-369241_3451713638.0DomainCUB 2
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3692456_25671713638.0DomainCUB 14
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3692567_26291713638.0DomainSushi 14
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3692630_26911713638.0DomainSushi 15
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3692757_28141713638.0DomainSushi 17
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3692815_28721713638.0DomainSushi 18
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3692873_29301713638.0DomainSushi 19
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3692931_29921713638.0DomainSushi 20
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3692993_30501713638.0DomainSushi 21
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3693054_31111713638.0DomainSushi 22
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3693112_31701713638.0DomainSushi 23
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3693171_32301713638.0DomainSushi 24
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3693231_32881713638.0DomainSushi 25
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3693289_33461713638.0DomainSushi 26
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3693350_34081713638.0DomainSushi 27
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3693409_34681713638.0DomainSushi 28
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-369484_5451713638.0DomainSushi 2
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-369548_6591713638.0DomainCUB 3
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-369662_7191713638.0DomainSushi 3
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-369721_8291713638.0DomainCUB 4
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-369832_8931713638.0DomainSushi 4
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-369895_10031713638.0DomainCUB 5
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3691008_10651713539.0DomainSushi 5
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3691067_11771713539.0DomainCUB 6
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3691180_12391713539.0DomainSushi 6
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3691241_13491713539.0DomainCUB 7
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3691352_14121713539.0DomainSushi 7
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3691414_15231713539.0DomainCUB 8
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3691526_15861713539.0DomainSushi 8
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3691588_16961713539.0DomainCUB 9
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3691699_17601713539.0DomainSushi 9
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3691762_18701713539.0DomainCUB 10
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-369176_2371713539.0DomainSushi 1
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3691876_19371713539.0DomainSushi 10
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3691939_20471713539.0DomainCUB 11
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3692050_21091713539.0DomainSushi 11
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3692111_22191713539.0DomainCUB 12
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3692222_22811713539.0DomainSushi 12
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3692283_23941713539.0DomainCUB 13
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3692393_24541713539.0DomainSushi 13
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-369241_3451713539.0DomainCUB 2
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3692456_25671713539.0DomainCUB 14
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3692567_26291713539.0DomainSushi 14
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3692630_26911713539.0DomainSushi 15
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3692757_28141713539.0DomainSushi 17
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3692815_28721713539.0DomainSushi 18
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3692873_29301713539.0DomainSushi 19
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3692931_29921713539.0DomainSushi 20
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3692993_30501713539.0DomainSushi 21
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3693054_31111713539.0DomainSushi 22
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3693112_31701713539.0DomainSushi 23
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3693171_32301713539.0DomainSushi 24
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3693231_32881713539.0DomainSushi 25
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3693289_33461713539.0DomainSushi 26
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3693350_34081713539.0DomainSushi 27
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3693409_34681713539.0DomainSushi 28
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-369484_5451713539.0DomainSushi 2
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-369548_6591713539.0DomainCUB 3
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-369662_7191713539.0DomainSushi 3
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-369721_8291713539.0DomainCUB 4
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-369832_8931713539.0DomainSushi 4
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-369895_10031713539.0DomainCUB 5
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3713652_37071713708.0Topological domainCytoplasmic
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-37164_36301713708.0Topological domainExtracellular
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4723652_37071313668.0Topological domainCytoplasmic
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-47264_36301313668.0Topological domainExtracellular
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3693652_37071713638.0Topological domainCytoplasmic
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-36964_36301713638.0Topological domainExtracellular
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3693652_37071713539.0Topological domainCytoplasmic
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-36964_36301713539.0Topological domainExtracellular
HgeneCSMD3chr8:114290821chr8:131964244ENST00000297405-3713631_36511713708.0TransmembraneHelical
HgeneCSMD3chr8:114290821chr8:131964244ENST00000343508-4723631_36511313668.0TransmembraneHelical
HgeneCSMD3chr8:114290821chr8:131964244ENST00000352409-3693631_36511713638.0TransmembraneHelical
HgeneCSMD3chr8:114290821chr8:131964244ENST00000455883-3693631_36511713539.0TransmembraneHelical
TgeneADCY8chr8:114290821chr8:131964244ENST00000286355118342_7153701252.0Topological domainCytoplasmic
TgeneADCY8chr8:114290821chr8:131964244ENST00000286355118183_2033701252.0TransmembraneHelical
TgeneADCY8chr8:114290821chr8:131964244ENST00000286355118212_2323701252.0TransmembraneHelical
TgeneADCY8chr8:114290821chr8:131964244ENST00000286355118247_2673701252.0TransmembraneHelical
TgeneADCY8chr8:114290821chr8:131964244ENST00000286355118274_2943701252.0TransmembraneHelical
TgeneADCY8chr8:114290821chr8:131964244ENST00000286355118296_3163701252.0TransmembraneHelical
TgeneADCY8chr8:114290821chr8:131964244ENST00000286355118321_3413701252.0TransmembraneHelical


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Fusion Gene Sequence for CSMD3-ADCY8


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>19777_19777_1_CSMD3-ADCY8_CSMD3_chr8_114290821_ENST00000343508_ADCY8_chr8_131964244_ENST00000286355_length(transcript)=3300nt_BP=565nt
TACACCCCTCGGCCCTTTGGAGGACCGGAGAGCCGGACGACGCCGCAGCCCTTGGGGGAGTCCAGCGCCAGCTGGCGAAAAGAAGCTTCA
TCTTCCAGATCATCCGGGAAAGGGGCAGAGGTGGCCGGTTGTTGCGACTCATAAACAACCTCTTCAGCACAACCCGGTTGAATGTGGAGT
TGGTTCCTTTGCTGGAAACCTGTACAGCTTGACCGACAGACAGCCTCAGGATTTATTTATACATGTGGTGGAACTTTAAAAGGACTTAAT
GGCACTATAGAAAGCCCTGGTTTTCCATATGGATATCCAAATGGTGCAAACTGCACATGGGTAATAATAGCAGAAGAACGAAATAGAATA
CAAATTGTTTTTCAGTCATTTGCTCTAGAAGAAGAATACGACTACTTATCATTATATGATGGACATCCTCATCCTACAAACTTTAGGACA
AGGTTAACAGGATTCCATCTGCCACCTCCAGTGACAAGTACCAAATCTGTGTTCTCACTACGTTTGACCAGTGATTTTGCAGTTAGTGCT
CATGGATTTAAGGTATATTACGAAGGAGCGGCTCGTGCTTTCTGTGCTCCCCCGGTTTGTTGTCCTGGAAATGATCAACGACATGACCAA
TGTGGAAGATGAGCACCTGCAGCACCAGTTCCATCGGATCTACATCCATCGCTATGAGAACGTCAGTATTCTTTTTGCAGATGTTAAAGG
ATTTACCAACCTCTCCACGACCTTGTCTGCTCAGGAGCTGGTCAGGATGCTCAACGAGCTCTTTGCCAGATTTGATCGACTGGCCCATGA
GCATCACTGCCTTCGTATTAAAATCCTGGGGGACTGCTACTACTGCGTGTCTGGACTTCCTGAGCCCCGCCAGGACCATGCCCACTGCTG
TGTTGAAATGGGTCTCAGCATGATCAAAACCATCAGGTATGTGCGGTCAAGGACAAAACACGATGTTGACATGAGGATTGGAATCCACTC
CGGCTCGGTGCTGTGCGGTGTTTTGGGACTAAGGAAGTGGCAGTTTGATGTCTGGTCTTGGGATGTGGATATTGCAAACAAACTCGAATC
TGGAGGAATCCCTGGGAGGATTCACATTTCCAAAGCCACGCTGGACTGTCTCAACGGTGACTATAACGTGGAAGAGGGCCATGGTAAAGA
GAGGAATGAATTCCTGAGGAAGCATAATATCGAAACTTACTTAATTAAGCAGCCTGAGGACAGTCTGCTGTCCTTGCCTGAAGATATCGT
CAAGGAGTCAGTGAGCTCCTCAGACCGGAGAAACAGTGGGGCCACATTCACTGAAGGATCCTGGAGCCCTGAACTGCCCTTTGATAATAT
CGTGGGGAAACAGAATACTCTGGCTGCCCTAACAAGAAATTCAATAAATCTGCTTCCAAACCATCTTGCACAAGCTTTGCATGTCCAGTC
TGGGCCTGAGGAAATTAACAAGAGAATAGAACATACCATCGACTTGCGGAGTGGCGATAAATTGAGAAGAGAGCATATCAAGCCATTCTC
ACTGATGTTTAAAGACTCCAGCCTGGAGCACAAGTATTCTCAAATGAGGGATGAAGTGTTCAAGTCAAACTTGGTCTGTGCATTTATCGT
TCTTCTATTTATCACGGCAATACAAAGTTTGCTTCCTTCTTCAAGAGTGATGCCAATGACCATCCAGTTCTCCATTCTGATTATGCTGCA
CTCGGCTCTGGTCCTCATCACCACAGCAGAGGATTATAAATGTTTGCCCCTCATCCTCCGGAAAACTTGCTGTTGGATTAATGAGACCTA
TTTGGCCCGGAACGTCATCATCTTTGCATCCATTTTGATTAATTTCCTGGGTGCCATCTTAAATATCCTGTGGTGTGATTTTGACAAGTC
GATACCCTTGAAGAACCTGACTTTCAATTCCTCAGCTGTGTTTACAGATATCTGCTCCTACCCAGAGTACTTTGTCTTCACGGGGGTGTT
GGCCATGGTGACCTGTGCAGTTTTCCTCCGGCTGAACTCCGTCCTGAAGCTGGCAGTGCTGCTGATCATGATTGCCATCTATGCCCTGCT
CACTGAGACCGTCTACGCAGGCCTCTTTCTGCGTTATGACAACCTCAACCACAGTGGAGAAGATTTCCTGGGGACCAAGGAGGTATCACT
GCTACTGATGGCCATGTTCCTCCTGGCTGTGTTCTACCATGGACAGCAGCTGGAGTACACAGCCCGCCTGGACTTCCTTTGGCGAGTACA
GGCCAAAGAGGAGATCAATGAGATGAAGGAGCTGAGGGAACACAATGAGAACATGCTCCGGAATATCTTACCCAGCCATGTGGCCCGCCA
TTTCCTAGAGAAGGACCGAGACAATGAGGAGCTGTATTCTCAATCCTATGATGCTGTTGGGGTGATGTTTGCCTCCATCCCAGGATTTGC
GGACTTTTACTCTCAGACTGAAATGAATAACCAGGGAGTGGAATGCCTGCGCTTGCTCAATGAGATCATTGCTGACTTCGATGAGTTGCT
TGGTGAAGACCGATTTCAAGACATTGAAAAGATTAAGACCATTGGCAGCACCTACATGGCCGTGTCAGGCCTGTCACCTGAAAAACAGCA
ATGTGAAGACAAGTGGGGACATTTGTGTGCTCTGGCTGACTTCTCACTCGCCCTGACAGAAAGCATACAGGAGATCAACAAGCATTCATT
CAACAATTTTGAACTCCGGATTGGCATCAGCCACGGCTCAGTGGTAGCTGGCGTTATCGGCGCTAAGAAACCACAGTATGACATTTGGGG
CAAAACTGTGAACCTGGCAAGCCGAATGGACAGCACGGGGGTTAGTGGCCGGATCCAAGTCCCAGAGGAGACCTATCTCATCCTGAAGGA
CCAGGGCTTTGCCTTTGATTACCGAGGGGAGATCTATGTGAAGGGTATCAGTGAACAGGAAGGAAAAATCAAAACGTACTTTCTTCTGGG
AAGAGTCCAACCCAACCCATTCATCTTGCCCCCAAGAAGACTGCCTGGGCAGTACTCCCTGGCCGCGGTTGTCCTGGGACTTGTCCAGTC
CCTCAATAGGCAAAGGCAGAAGCAGCTACTCAATGAGAACAACAACACAGGAATCATCAAGGGTCATTACAACCGGCGGACTTTGTTGTC
ACCCAGCGGCACAGAGCCTGGAGCCCAGGCTGAAGGCACCGACAAATCTGATTTGCCATAAAAGCATTTTCTTTCTGTTTTTTTTTTTTG

>19777_19777_1_CSMD3-ADCY8_CSMD3_chr8_114290821_ENST00000343508_ADCY8_chr8_131964244_ENST00000286355_length(amino acids)=894AA_BP=13
MQLVLMDLRYITKERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFD
RLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIA
NKLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEDSLLSLPEDIVKESVSSSDRRNSGATFTEGSWSPEL
PFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLV
CAFIVLLFITAIQSLLPSSRVMPMTIQFSILIMLHSALVLITTAEDYKCLPLILRKTCCWINETYLARNVIIFASILINFLGAILNILWC
DFDKSIPLKNLTFNSSAVFTDICSYPEYFVFTGVLAMVTCAVFLRLNSVLKLAVLLIMIAIYALLTETVYAGLFLRYDNLNHSGEDFLGT
KEVSLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFAS
IPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEI
NKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFAFDYRGEIYVKGISEQEGKIKT

--------------------------------------------------------------
>19777_19777_2_CSMD3-ADCY8_CSMD3_chr8_114290821_ENST00000343508_ADCY8_chr8_131964244_ENST00000377928_length(transcript)=2818nt_BP=565nt
TACACCCCTCGGCCCTTTGGAGGACCGGAGAGCCGGACGACGCCGCAGCCCTTGGGGGAGTCCAGCGCCAGCTGGCGAAAAGAAGCTTCA
TCTTCCAGATCATCCGGGAAAGGGGCAGAGGTGGCCGGTTGTTGCGACTCATAAACAACCTCTTCAGCACAACCCGGTTGAATGTGGAGT
TGGTTCCTTTGCTGGAAACCTGTACAGCTTGACCGACAGACAGCCTCAGGATTTATTTATACATGTGGTGGAACTTTAAAAGGACTTAAT
GGCACTATAGAAAGCCCTGGTTTTCCATATGGATATCCAAATGGTGCAAACTGCACATGGGTAATAATAGCAGAAGAACGAAATAGAATA
CAAATTGTTTTTCAGTCATTTGCTCTAGAAGAAGAATACGACTACTTATCATTATATGATGGACATCCTCATCCTACAAACTTTAGGACA
AGGTTAACAGGATTCCATCTGCCACCTCCAGTGACAAGTACCAAATCTGTGTTCTCACTACGTTTGACCAGTGATTTTGCAGTTAGTGCT
CATGGATTTAAGGTATATTACGAAGGAGCGGCTCGTGCTTTCTGTGCTCCCCCGGTTTGTTGTCCTGGAAATGATCAACGACATGACCAA
TGTGGAAGATGAGCACCTGCAGCACCAGTTCCATCGGATCTACATCCATCGCTATGAGAACGTCAGTATTCTTTTTGCAGATGTTAAAGG
ATTTACCAACCTCTCCACGACCTTGTCTGCTCAGGAGCTGGTCAGGATGCTCAACGAGCTCTTTGCCAGATTTGATCGACTGGCCCATGA
GCATCACTGCCTTCGTATTAAAATCCTGGGGGACTGCTACTACTGCGTGTCTGGACTTCCTGAGCCCCGCCAGGACCATGCCCACTGCTG
TGTTGAAATGGGTCTCAGCATGATCAAAACCATCAGGTATGTGCGGTCAAGGACAAAACACGATGTTGACATGAGGATTGGAATCCACTC
CGGCTCGGTGCTGTGCGGTGTTTTGGGACTAAGGAAGTGGCAGTTTGATGTCTGGTCTTGGGATGTGGATATTGCAAACAAACTCGAATC
TGGAGGAATCCCTGGGAGGATTCACATTTCCAAAGCCACGCTGGACTGTCTCAACGGTGACTATAACGTGGAAGAGGGCCATGGTAAAGA
GAGGAATGAATTCCTGAGGAAGCATAATATCGAAACTTACTTAATTAAGCAGCCTGAGGACAGTCTGCTGTCCTTGCCTGAAGATATCGT
CAAGGAGTCAGTGAGCTCCTCAGACCGGAGAAACAGTGGGGCCACATTCACTGAAGGATCCTGGAGCCCTGAACTGCCCTTTGATAATAT
CGTGGGGAAACAGAATACTCTGGCTGCCCTAACAAGAAATTCAATAAATCTGCTTCCAAACCATCTTGCACAAGCTTTGCATGTCCAGTC
TGGGCCTGAGGAAATTAACAAGAGAATAGAACATACCATCGACTTGCGGAGTGGCGATAAATTGAGAAGAGAGCATATCAAGCCATTCTC
ACTGATGTTTAAAGACTCCAGCCTGGAGCACAAGTACTTTGTCTTCACGGGGGTGTTGGCCATGGTGACCTGTGCAGTTTTCCTCCGGCT
GAACTCCGTCCTGAAGCTGGCAGTGCTGCTGATCATGATTGCCATCTATGCCCTGCTCACTGAGACCGTCTACGCAGGCCTCTTTCTGCG
TTATGACAACCTCAACCACAGTGGAGAAGATTTCCTGGGGACCAAGGAGGTATCACTGCTACTGATGGCCATGTTCCTCCTGGCTGTGTT
CTACCATGGACAGCAGCTGGAGTACACAGCCCGCCTGGACTTCCTTTGGCGAGTACAGGCCAAAGAGGAGATCAATGAGATGAAGGAGCT
GAGGGAACACAATGAGAACATGCTCCGGAATATCTTACCCAGCCATGTGGCCCGCCATTTCCTAGAGAAGGACCGAGACAATGAGGAGCT
GTATTCTCAATCCTATGATGCTGTTGGGGTGATGTTTGCCTCCATCCCAGGATTTGCGGACTTTTACTCTCAGACTGAAATGAATAACCA
GGGAGTGGAATGCCTGCGCTTGCTCAATGAGATCATTGCTGACTTCGATGAGTTGCTTGGTGAAGACCGATTTCAAGACATTGAAAAGAT
TAAGACCATTGGCAGCACCTACATGGCCGTGTCAGGCCTGTCACCTGAAAAACAGCAATGTGAAGACAAGTGGGGACATTTGTGTGCTCT
GGCTGACTTCTCACTCGCCCTGACAGAAAGCATACAGGAGATCAACAAGCATTCATTCAACAATTTTGAACTCCGGATTGGCATCAGCCA
CGGCTCAGTGGTAGCTGGCGTTATCGGCGCTAAGAAACCACAGTATGACATTTGGGGCAAAACTGTGAACCTGGCAAGCCGAATGGACAG
CACGGGGGTTAGTGGCCGGATCCAAGTCCCAGAGGAGACCTATCTCATCCTGAAGGACCAGGGCTTTGCCTTTGATTACCGAGGGGAGAT
CTATGTGAAGGGTATCAGTGAACAGGAAGGAAAAATCAAAACGTACTTTCTTCTGGGAAGAGTCCAACCCAACCCATTCATCTTGCCCCC
AAGAAGACTGCCTGGGCAGTACTCCCTGGCCGCGGTTGTCCTGGGACTTGTCCAGTCCCTCAATAGGCAAAGGCAGAAGCAGCTACTCAA
TGAGAACAACAACACAGGAATCATCAAGGGTCATTACAACCGGCGGACTTTGTTGTCACCCAGCGGCACAGAGCCTGGAGCCCAGGCTGA

>19777_19777_2_CSMD3-ADCY8_CSMD3_chr8_114290821_ENST00000343508_ADCY8_chr8_131964244_ENST00000377928_length(amino acids)=764AA_BP=13
MQLVLMDLRYITKERLVLSVLPRFVVLEMINDMTNVEDEHLQHQFHRIYIHRYENVSILFADVKGFTNLSTTLSAQELVRMLNELFARFD
RLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRYVRSRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIA
NKLESGGIPGRIHISKATLDCLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEDSLLSLPEDIVKESVSSSDRRNSGATFTEGSWSPEL
PFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDLRSGDKLRREHIKPFSLMFKDSSLEHKYFVFTGVLAMVTCA
VFLRLNSVLKLAVLLIMIAIYALLTETVYAGLFLRYDNLNHSGEDFLGTKEVSLLLMAMFLLAVFYHGQQLEYTARLDFLWRVQAKEEIN
EMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQSYDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQ
DIEKIKTIGSTYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVVAGVIGAKKPQYDIWGKTVNLA
SRMDSTGVSGRIQVPEETYLILKDQGFAFDYRGEIYVKGISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CSMD3-ADCY8


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CSMD3-ADCY8


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CSMD3-ADCY8


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource