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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:CSNK2B-CCT5 (FusionGDB2 ID:19888)

Fusion Gene Summary for CSNK2B-CCT5

Fusion gene summary

Fusion gene information	Fusion gene name: CSNK2B-CCT5
	Fusion gene ID: 19888
		Hgene	Tgene
	Gene symbol	CSNK2B	CCT5
	Gene ID	1460	22948
	Gene name	casein kinase 2 beta	chaperonin containing TCP1 subunit 5
	Synonyms	CK2B\|CK2N\|CSK2B\|Ckb1\|Ckb2\|G5A\|POBINDS	CCT-epsilon\|CCTE\|HEL-S-69\|PNAS-102\|TCP-1-epsilon
	Cytomap	6p21.33	5p15.2
	Type of gene	protein-coding	protein-coding
	Description	casein kinase II subunit betaCK II betaCSNK2B-LY6G5B-1072CSNK2B-LY6G5B-1103CSNK2B-LY6G5B-532CSNK2B-LY6G5B-560CSNK2B-LY6G5B-562Casein kinase II beta subunitalternative name: G5a, phosvitincasein kinase 2, beta polypeptidecasein kinase II b subuni	T-complex protein 1 subunit epsilonchaperonin containing TCP1, subunit 5 (epsilon)epididymis secretory protein Li 69
	Modification date	20200327	20200313
	UniProtAcc	P67870	P48643
	Ensembl transtripts involved in fusion gene	ENST00000375865, ENST00000375866, ENST00000375882, ENST00000375885, ENST00000383427, ENST00000383431, ENST00000383433, ENST00000400110, ENST00000400116, ENST00000412802, ENST00000413083, ENST00000416194, ENST00000418230, ENST00000422261, ENST00000422567, ENST00000424502, ENST00000428483, ENST00000429633, ENST00000431476, ENST00000432290, ENST00000436169, ENST00000437010, ENST00000439572, ENST00000443673, ENST00000448596, ENST00000451917, ENST00000452985, ENST00000453234, ENST00000454382, ENST00000454511, ENST00000455161, ENST00000458330, ENST00000464220, ENST00000468132, ENST00000476022, ENST00000480866, ENST00000485003, ENST00000488020,	ENST00000503026, ENST00000506600, ENST00000515390, ENST00000515676, ENST00000280326,
Fusion gene scores	* DoF score	6 X 6 X 4=144	58 X 14 X 17=13804
	# samples	6	61
	** MAII score	log2(6/144*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(61/13804*10)=-4.50013332598527 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: CSNK2B [Title/Abstract] AND CCT5 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	CSNK2B(31637847)-CCT5(10250033), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	CSNK2B	GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation	19592636
Hgene	CSNK2B	GO:0018107	peptidyl-threonine phosphorylation	15723517
Hgene	CSNK2B	GO:0033211	adiponectin-activated signaling pathway	19233263
Hgene	CSNK2B	GO:0043537	negative regulation of blood vessel endothelial cell migration	19592636

Fusion gene breakpoints across CSNK2B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across CCT5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	UCS	TCGA-ND-A4W6-01A	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+

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Fusion Gene ORF analysis for CSNK2B-CCT5

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000375865	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
5CDS-intron	ENST00000375865	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
5CDS-intron	ENST00000375865	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
5CDS-intron	ENST00000375865	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
5CDS-intron	ENST00000375866	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
5CDS-intron	ENST00000375866	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
5CDS-intron	ENST00000375866	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
5CDS-intron	ENST00000375866	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
5CDS-intron	ENST00000375882	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
5CDS-intron	ENST00000375882	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
5CDS-intron	ENST00000375882	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
5CDS-intron	ENST00000375882	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
5CDS-intron	ENST00000375885	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
5CDS-intron	ENST00000375885	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
5CDS-intron	ENST00000375885	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
5CDS-intron	ENST00000375885	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
In-frame	ENST00000375865	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
In-frame	ENST00000375866	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
In-frame	ENST00000375882	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
In-frame	ENST00000375885	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000383427	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000383431	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000383433	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000400110	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000400116	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000412802	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000413083	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000416194	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000418230	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000422261	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000422567	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000424502	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000428483	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000429633	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000431476	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000432290	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000436169	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000437010	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000439572	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000443673	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000448596	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000451917	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000452985	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000453234	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000454382	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000454511	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000455161	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000458330	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000464220	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000468132	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000476022	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000480866	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000485003	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-3CDS	ENST00000488020	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000383427	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000383427	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000383427	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000383427	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000383431	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000383431	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000383431	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000383431	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000383433	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000383433	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000383433	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000383433	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000400110	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000400110	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000400110	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000400110	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000400116	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000400116	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000400116	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000400116	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000412802	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000412802	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000412802	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000412802	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000413083	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000413083	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000413083	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000413083	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000416194	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000416194	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000416194	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000416194	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000418230	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000418230	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000418230	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000418230	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000422261	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000422261	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000422261	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000422261	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000422567	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000422567	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000422567	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000422567	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000424502	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000424502	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000424502	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000424502	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000428483	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000428483	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000428483	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000428483	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000429633	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000429633	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000429633	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000429633	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000431476	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000431476	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000431476	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000431476	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000432290	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000432290	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000432290	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000432290	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000436169	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000436169	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000436169	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000436169	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000437010	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000437010	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000437010	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000437010	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000439572	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000439572	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000439572	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000439572	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000443673	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000443673	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000443673	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000443673	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000448596	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000448596	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000448596	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000448596	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000451917	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000451917	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000451917	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000451917	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000452985	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000452985	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000452985	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000452985	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000453234	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000453234	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000453234	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000453234	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000454382	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000454382	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000454382	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000454382	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000454511	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000454511	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000454511	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000454511	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000455161	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000455161	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000455161	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000455161	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000458330	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000458330	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000458330	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000458330	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000464220	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000464220	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000464220	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000464220	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000468132	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000468132	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000468132	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000468132	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000476022	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000476022	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000476022	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000476022	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000480866	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000480866	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000480866	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000480866	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000485003	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000485003	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000485003	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000485003	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000488020	ENST00000503026	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000488020	ENST00000506600	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000488020	ENST00000515390	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+
intron-intron	ENST00000488020	ENST00000515676	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000375885	CSNK2B	chr6	31637847	-	ENST00000280326	CCT5	chr5	10250033	+	4736	1061	1451	3106	551
ENST00000375882	CSNK2B	chr6	31637847	-	ENST00000280326	CCT5	chr5	10250033	+	4623	948	1338	2993	551
ENST00000375865	CSNK2B	chr6	31637847	-	ENST00000280326	CCT5	chr5	10250033	+	4583	908	1298	2953	551
ENST00000375866	CSNK2B	chr6	31637847	-	ENST00000280326	CCT5	chr5	10250033	+	4611	936	1326	2981	551

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000375885	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+	0.000936709	0.9990633
ENST00000375882	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+	0.000862135	0.9991379
ENST00000375865	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+	0.000854239	0.99914575
ENST00000375866	ENST00000280326	CSNK2B	chr6	31637847	-	CCT5	chr5	10250033	+	0.000830525	0.99916947

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Fusion Genomic Features for CSNK2B-CCT5

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CSNK2B-CCT5

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:31637847/chr5:10250033)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
CSNK2B P67870	CCT5 P48643
FUNCTION: Regulatory subunit of casein kinase II/CK2. As part of the kinase complex regulates the basal catalytic activity of the alpha subunit a constitutively active serine/threonine-protein kinase that phosphorylates a large number of substrates containing acidic residues C-terminal to the phosphorylated serine or threonine (PubMed:11239457, PubMed:16818610). Participates in Wnt signaling (By similarity). {ECO:0000250\|UniProtKB:P67871, ECO:0000269\|PubMed:11239457, ECO:0000269\|PubMed:16818610}.	FUNCTION: Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444). The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444). As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638). The TRiC complex plays a role in the folding of actin and tubulin (Probable). {ECO:0000269\|PubMed:20080638, ECO:0000269\|PubMed:25467444, ECO:0000305}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000375865

55_64

264

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000375866

55_64

264

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000375882

55_64

264

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000383427

55_64

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000383433

55_64

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000400110

55_64

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000412802

55_64

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000418230

55_64

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000422567

55_64

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000429633

55_64

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000431476

55_64

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000436169

55_64

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000443673

55_64

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000448596

55_64

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000451917

55_64

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000452985

55_64

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000453234

55_64

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000454382

55_64

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000454511

55_64

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000455161

55_64

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

Hgene

CSNK2B

chr6:31637847

chr5:10250033

ENST00000458330

55_64

216.0

Compositional bias

Note=Asp/Glu-rich (acidic)

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Fusion Gene Sequence for CSNK2B-CCT5

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>19888_19888_1_CSNK2B-CCT5_CSNK2B_chr6_31637847_ENST00000375865_CCT5_chr5_10250033_ENST00000280326_length(transcript)=4583nt_BP=908nt
GGAGGAAGCGACCAGGTCCGGCACGAAGGAGGGAGAGGTGGCCTGAGGAGCGGAGGGGGGATGTGTGGATTCCGGTGAAAGGGACCTGAC
AATCGCCCCCAACCCCTGACGTGAAGATGAGCAGCTCAGAGGAGGTGTCCTGGATTTCCTGGTTCTGTGGGCTCCGTGGCAATGAATTCT
TCTGTGAAGTGGATGAAGACTACATCCAGGACAAATTTAATCTTACTGGACTCAATGAGCAGGTCCCTCACTATCGACAAGCTCTAGACA
TGATCTTGGACCTGGAGCCTGATGAAGAACTGGAAGACAACCCCAACCAGAGTGACCTGATTGAGCAGGCAGCCGAGATGCTTTATGGAT
TGATCCACGCCCGCTACATCCTTACCAACCGTGGCATCGCCCAGATGTTGGAAAAGTACCAGCAAGGAGACTTTGGTTACTGTCCTCGTG
TGTACTGTGAGAACCAGCCAATGCTTCCCATTGGCCTTTCAGACATCCCAGGTGAAGCCATGGTGAAGCTCTACTGCCCCAAGTGCATGG
ATGTGTACACACCCAAGTCATCAAGACACCATCACACGGATGGCGCCTACTTCGGCACTGGTTTCCCTCACATGCTCTTCATGGTGCATC
CCGAGTACCGGCCCAAGAGACCTGCCAACCAGTTTGTGCCCAGGCTCTACGGTTTCAAGATCCATCCGATGGCCTACCAGCTGCAGCTCC
AAGCCGCCAGCAACTTCAAGAGCCCAGTCAAGACGATTCGCTGATTCCCTCCCCCACCTGTCCTGCAGTCTTTGACTTTTCCTTTCTTTT
TTGCCACCCTTTCAGGAACCCTGTATGGTTTTTAGTTTAAATTAAAGGAGTCGTTATCGTGGTGGGAATATGAAATAAAGTAGAAGAAAA
GGCCATGAAAAAAAAAAAAAAACCGGAAATGGGTCCTACCATCTTCTCGGAGCCGGAGTGCGAAGAAATAAAGAAATAGTGCTTTAAGTC
AATGAATTCCTCCTTGGGACCCACTATCGAGAAACTATCAGTGGTAACGTTTTAAAAAATGACAAATTCAATCTGCTCTTGACTTGTGTG
TCCTAAGATTTCCACTAAGTGTCTTCAAACCTCCCCCTCCCCGGCTTCCTGGATAATAGAAGTTCCCGAAGGCCGCCGATTCCAGAAGAT
ACTGTCTGGCGTGAAATTAGTCTCAGTAGAAACATAAGTCCCGCGCGTCTTGTGCTGCGCGTGCGCAAGCTTTTGGGCCCTCCCGAGAAA
GGGAAGTGCATTCTCGCTTCCGTAGCGGTCTCCGCCGGTTGGGGGGAAGTAATTCCGGTTGTTGCACCATGGCGTCCATGGGGACCCTCG
CCTTCGATGAATATGGGCGCCCTTTCCTCATCATCAAGGATCAGGACCGCAAGTCCCGTCTTATGGGACTTGAGGCCCTCAAGTCTCATA
TAATGGCAGCAAAGGCTGTAGCAAATACAATGAGAACATCACTTGGACCAAATGGGCTTGATAAGATGATGGTGGATAAGGATGGAGATG
TGACTGTAACTAATGATGGGGCCACCATCTTAAGCATGATGGATGTTGATCATCAGATTGCCAAGCTGATGGTGGAACTGTCCAAGTCTC
AGGATGATGAAATTGGAGATGGAACCACAGGAGTGGTTGTCCTGGCTGGTGCCTTGTTAGAAGAAGCGGAGCAATTGCTAGACCGAGGCA
TTCACCCAATCAGAATAGCCGATGGCTATGAGCAGGCTGCTCGTGTTGCTATTGAACACCTGGACAAGATCAGCGATAGCGTCCTTGTTG
ACATAAAGGACACCGAACCCCTGATTCAGACAGCAAAAACCACGCTGGGCTCCAAAGTGGTCAACAGTTGTCACCGACAGATGGCTGAGA
TTGCTGTGAATGCCGTCCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTTATCAAAGTAGAAGGCAAAGTGGGCGGCA
GGCTGGAGGACACTAAACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAGATGCCAAAAAAAGTGGAAGATGCGAAGA
TTGCAATTCTCACATGTCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTGACCTCTGTCGAAGATTATAAAGCCCTTC
AGAAATACGAAAAGGAGAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAACCTAGCAATTTGTCAGTGGGGCTTTGATG
ATGAAGCAAATCACTTACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCTGAAATTGAGCTGATTGCCATCGCAACAG
GAGGGCGGATCGTCCCCAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTTGTACAGGAGATCTCATTTGGGACAACTA
AGGATAAAATGCTGGTCATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGAGGAGGAAATAAGATGATCATTGAGGAGG
CGAAACGATCCCTTCACGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTGGTGTATGGAGGAGGGGCTGCTGAGATAT
CCTGTGCCCTGGCAGTTAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATGAGAGCGTTTGCCGACGCACTGGAGGTCA
TCCCCATGGCCCTCTCTGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGAGCCAGACAGGTGAAGGAGATGAACCCTG
CTCTTGGCATCGACTGTTTGCACAAGGGGACAAATGATATGAAGCAACAGCATGTCATAGAAACCTTGATTGGCAAAAAGCAACAGATAT
CTCTTGCAACACAAATGGTTAGAATGATTTTGAAGATTGATGACATTCGTAAGCCTGGAGAATCTGAAGAATGAAGACATTGAGAAAACT
ATGTAGCAAGATCCACTTCTGTGATTAAGTAAATGGATGTCTCGTGATGCATCTACAGTTATTTATTGTTACATCCTTTTCCAGACACTG
TAGATGCTATAATAAAAATAGCTGTTTGGTAACCATAGTTTCACTTGTTCAAAGCTGTGTAATCGTGGGGGTACCATCTCAACTGCTTTT
GTATTCATTGTATTAAAAGAATCTGTTTAAACAACCTTTATCTTCTCTTCGGGTTTAAGAAACGTTTATTGTAACAGTAATTAAATGCTG
CCTTAATTGAAGGGGTTTGGGTGGATTTTTTTTTCTCAAAATAAGCTGTAGGGACTATTTTAACAGCTTAAACAGGAGCTCTCAAGATGC
ACTTTCATATTGAGAGGAATATGGGCTTGATCCTCTTCCTATCTAAATGGGTGGGCCATTTGATTGTAGAGGGTCCACCACAGAATTATG
GGATGCCTTAAGTGCTGTTACTAGGTTGCTCACAGCCTAACCTGGCGTGTTGTTTAGGGCTGATGGAGACCCATGTGAGCCTTTGCTTTC
CTCTGGCCCCGGCCCCACCCTGAACACAGCTCATACACAGAATCAGGACCAGCATGTGCAGAGCTGGCCACCAGCACAGGCTTAGGGCAG
TTCAGAACCCACTTGTTTCCCTATCAGAGGGACACAGTGAAGTGGAGGTTAAAGTAAATTACAGGAAATAAGGGAGAAATCTTGCAGTTA
CCATGTTCAGATAGAGTGACTGAAATTAATTGTACTTACTAAAGTATTAACTAGCTAACAGTGATGGGCCAAGACGCTCCGAGAACTCTA
CCGGGATTGTCTGTTCTGACAACCCAGTGAGGCAGATACACTTTCTTACTGCTCACATCTTACAGGTGAGTACTCATAATTGGCCAGCAT
CTCACCACCAGCAAGTAGTAGGGCCAGGTCAATCCCAGGCAGTCTGACCCCAGAGTGGCCCAGCTCATCCCCTACTCTGTTATTTGCTTG
TTAATGATTCTCTAGATTTTCTAAAATAATGTTTCTTAGCATTGTGATGATAAAGCTCATGATGAACTTTATCACTAGTTATGCCACCTT
AACTAGTCAGATTTCCTAGAATTAGGAAATGGTGACTCTTGTCTAAATTTGGTTAAGTGATGAATTTGGGTTACCGTCTCATGTGAACCT
GGAGATTCACCAGTCTTAACTTTTGGGTCATTGTGTTTTCTCTACATTCATGCATTGGATGTTTTGCTAAATAACTCCTGTGGATTTAGG
AATGTGTGCTAATAGCAATCTTCCTAATTTTCATGTTTATATGGAACTATGCAGTTGAGTATTGAAAGCTTTAAACTGAGTTTATTTACA
AGGACTGAGTCTAGCCTACAGAGAACATACAGCAGCCTTCTTTGGACCACAGTCTTATCCGAGGGGTCTGTGGTTGTATCAGAAGAGCCA
CTAAACCAATCCCCCTTTCCAAAATTGAACCTCACAGACGTTCCTGTTTTTTGTGATTGAGAAACTGGTCAATGAACAGGAAGACTTAGA

>19888_19888_1_CSNK2B-CCT5_CSNK2B_chr6_31637847_ENST00000375865_CCT5_chr5_10250033_ENST00000280326_length(amino acids)=551AA_BP=
MGGSNSGCCTMASMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSM
MDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAK
TTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKP
KTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTA
EKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKC
PTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKI

--------------------------------------------------------------
>19888_19888_2_CSNK2B-CCT5_CSNK2B_chr6_31637847_ENST00000375866_CCT5_chr5_10250033_ENST00000280326_length(transcript)=4611nt_BP=936nt
TGTGGATTCCGGTGAAAGGGACCTGACAATCGCCCCCAACCCGTGAGAAAAGGAGGAGCCCAGTTCTTGCTTGAGAATGATAAACTTGGA
AACCCTTGGGAAAGGCGTGGGGGTCATGCAGAGACTTGTATTGCTGACGTGAAGATGAGCAGCTCAGAGGAGGTGTCCTGGATTTCCTGG
TTCTGTGGGCTCCGTGGCAATGAATTCTTCTGTGAAGTGGATGAAGACTACATCCAGGACAAATTTAATCTTACTGGACTCAATGAGCAG
GTCCCTCACTATCGACAAGCTCTAGACATGATCTTGGACCTGGAGCCTGATGAAGAACTGGAAGACAACCCCAACCAGAGTGACCTGATT
GAGCAGGCAGCCGAGATGCTTTATGGATTGATCCACGCCCGCTACATCCTTACCAACCGTGGCATCGCCCAGATGTTGGAAAAGTACCAG
CAAGGAGACTTTGGTTACTGTCCTCGTGTGTACTGTGAGAACCAGCCAATGCTTCCCATTGGCCTTTCAGACATCCCAGGTGAAGCCATG
GTGAAGCTCTACTGCCCCAAGTGCATGGATGTGTACACACCCAAGTCATCAAGACACCATCACACGGATGGCGCCTACTTCGGCACTGGT
TTCCCTCACATGCTCTTCATGGTGCATCCCGAGTACCGGCCCAAGAGACCTGCCAACCAGTTTGTGCCCAGGCTCTACGGTTTCAAGATC
CATCCGATGGCCTACCAGCTGCAGCTCCAAGCCGCCAGCAACTTCAAGAGCCCAGTCAAGACGATTCGCTGATTCCCTCCCCCACCTGTC
CTGCAGTCTTTGACTTTTCCTTTCTTTTTTGCCACCCTTTCAGGAACCCTGTATGGTTTTTAGTTTAAATTAAAGGAGTCGTTATCGTGG
TGGGAATATGAAATAAAGTAGAAGAAAAGGCCATGAAAAAAAAAAAAAAACCGGAAATGGGTCCTACCATCTTCTCGGAGCCGGAGTGCG
AAGAAATAAAGAAATAGTGCTTTAAGTCAATGAATTCCTCCTTGGGACCCACTATCGAGAAACTATCAGTGGTAACGTTTTAAAAAATGA
CAAATTCAATCTGCTCTTGACTTGTGTGTCCTAAGATTTCCACTAAGTGTCTTCAAACCTCCCCCTCCCCGGCTTCCTGGATAATAGAAG
TTCCCGAAGGCCGCCGATTCCAGAAGATACTGTCTGGCGTGAAATTAGTCTCAGTAGAAACATAAGTCCCGCGCGTCTTGTGCTGCGCGT
GCGCAAGCTTTTGGGCCCTCCCGAGAAAGGGAAGTGCATTCTCGCTTCCGTAGCGGTCTCCGCCGGTTGGGGGGAAGTAATTCCGGTTGT
TGCACCATGGCGTCCATGGGGACCCTCGCCTTCGATGAATATGGGCGCCCTTTCCTCATCATCAAGGATCAGGACCGCAAGTCCCGTCTT
ATGGGACTTGAGGCCCTCAAGTCTCATATAATGGCAGCAAAGGCTGTAGCAAATACAATGAGAACATCACTTGGACCAAATGGGCTTGAT
AAGATGATGGTGGATAAGGATGGAGATGTGACTGTAACTAATGATGGGGCCACCATCTTAAGCATGATGGATGTTGATCATCAGATTGCC
AAGCTGATGGTGGAACTGTCCAAGTCTCAGGATGATGAAATTGGAGATGGAACCACAGGAGTGGTTGTCCTGGCTGGTGCCTTGTTAGAA
GAAGCGGAGCAATTGCTAGACCGAGGCATTCACCCAATCAGAATAGCCGATGGCTATGAGCAGGCTGCTCGTGTTGCTATTGAACACCTG
GACAAGATCAGCGATAGCGTCCTTGTTGACATAAAGGACACCGAACCCCTGATTCAGACAGCAAAAACCACGCTGGGCTCCAAAGTGGTC
AACAGTTGTCACCGACAGATGGCTGAGATTGCTGTGAATGCCGTCCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTT
ATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAGGACACTAAACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAG
ATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATTCTCACATGTCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTG
ACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATACGAAAAGGAGAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAAC
CTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCAAATCACTTACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCT
GAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGGATCGTCCCCAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTT
GTACAGGAGATCTCATTTGGGACAACTAAGGATAAAATGCTGGTCATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGA
GGAGGAAATAAGATGATCATTGAGGAGGCGAAACGATCCCTTCACGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTG
GTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCCCTGGCAGTTAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATG
AGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATGGCCCTCTCTGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGA
GCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGCATCGACTGTTTGCACAAGGGGACAAATGATATGAAGCAACAGCATGTCATAGAA
ACCTTGATTGGCAAAAAGCAACAGATATCTCTTGCAACACAAATGGTTAGAATGATTTTGAAGATTGATGACATTCGTAAGCCTGGAGAA
TCTGAAGAATGAAGACATTGAGAAAACTATGTAGCAAGATCCACTTCTGTGATTAAGTAAATGGATGTCTCGTGATGCATCTACAGTTAT
TTATTGTTACATCCTTTTCCAGACACTGTAGATGCTATAATAAAAATAGCTGTTTGGTAACCATAGTTTCACTTGTTCAAAGCTGTGTAA
TCGTGGGGGTACCATCTCAACTGCTTTTGTATTCATTGTATTAAAAGAATCTGTTTAAACAACCTTTATCTTCTCTTCGGGTTTAAGAAA
CGTTTATTGTAACAGTAATTAAATGCTGCCTTAATTGAAGGGGTTTGGGTGGATTTTTTTTTCTCAAAATAAGCTGTAGGGACTATTTTA
ACAGCTTAAACAGGAGCTCTCAAGATGCACTTTCATATTGAGAGGAATATGGGCTTGATCCTCTTCCTATCTAAATGGGTGGGCCATTTG
ATTGTAGAGGGTCCACCACAGAATTATGGGATGCCTTAAGTGCTGTTACTAGGTTGCTCACAGCCTAACCTGGCGTGTTGTTTAGGGCTG
ATGGAGACCCATGTGAGCCTTTGCTTTCCTCTGGCCCCGGCCCCACCCTGAACACAGCTCATACACAGAATCAGGACCAGCATGTGCAGA
GCTGGCCACCAGCACAGGCTTAGGGCAGTTCAGAACCCACTTGTTTCCCTATCAGAGGGACACAGTGAAGTGGAGGTTAAAGTAAATTAC
AGGAAATAAGGGAGAAATCTTGCAGTTACCATGTTCAGATAGAGTGACTGAAATTAATTGTACTTACTAAAGTATTAACTAGCTAACAGT
GATGGGCCAAGACGCTCCGAGAACTCTACCGGGATTGTCTGTTCTGACAACCCAGTGAGGCAGATACACTTTCTTACTGCTCACATCTTA
CAGGTGAGTACTCATAATTGGCCAGCATCTCACCACCAGCAAGTAGTAGGGCCAGGTCAATCCCAGGCAGTCTGACCCCAGAGTGGCCCA
GCTCATCCCCTACTCTGTTATTTGCTTGTTAATGATTCTCTAGATTTTCTAAAATAATGTTTCTTAGCATTGTGATGATAAAGCTCATGA
TGAACTTTATCACTAGTTATGCCACCTTAACTAGTCAGATTTCCTAGAATTAGGAAATGGTGACTCTTGTCTAAATTTGGTTAAGTGATG
AATTTGGGTTACCGTCTCATGTGAACCTGGAGATTCACCAGTCTTAACTTTTGGGTCATTGTGTTTTCTCTACATTCATGCATTGGATGT
TTTGCTAAATAACTCCTGTGGATTTAGGAATGTGTGCTAATAGCAATCTTCCTAATTTTCATGTTTATATGGAACTATGCAGTTGAGTAT
TGAAAGCTTTAAACTGAGTTTATTTACAAGGACTGAGTCTAGCCTACAGAGAACATACAGCAGCCTTCTTTGGACCACAGTCTTATCCGA
GGGGTCTGTGGTTGTATCAGAAGAGCCACTAAACCAATCCCCCTTTCCAAAATTGAACCTCACAGACGTTCCTGTTTTTTGTGATTGAGA
AACTGGTCAATGAACAGGAAGACTTAGAGATGTTTCACAAGCCTTTGATTTTTGTTTCATTTATTTGTAATAAACCTCTTCCACGTGATG

>19888_19888_2_CSNK2B-CCT5_CSNK2B_chr6_31637847_ENST00000375866_CCT5_chr5_10250033_ENST00000280326_length(amino acids)=551AA_BP=
MGGSNSGCCTMASMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSM
MDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAK
TTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKP
KTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTA
EKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKC
PTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKI

--------------------------------------------------------------
>19888_19888_3_CSNK2B-CCT5_CSNK2B_chr6_31637847_ENST00000375882_CCT5_chr5_10250033_ENST00000280326_length(transcript)=4623nt_BP=948nt
CTTCCCCACCCTCCCTAATTTCCACTCCCCCCACCCCACTTCGCCTGCCGCGGTCGGGTCCGCGGCCTGCGCTGTAGCGGTCGCCGCCGT
TCCCTGGAAGTAGCAACTTCCCTACCCCACCCCAGTCCTGGTCCCCGTCCAGCCGCTGACGTGAAGATGAGCAGCTCAGAGGAGGTGTCC
TGGATTTCCTGGTTCTGTGGGCTCCGTGGCAATGAATTCTTCTGTGAAGTGGATGAAGACTACATCCAGGACAAATTTAATCTTACTGGA
CTCAATGAGCAGGTCCCTCACTATCGACAAGCTCTAGACATGATCTTGGACCTGGAGCCTGATGAAGAACTGGAAGACAACCCCAACCAG
AGTGACCTGATTGAGCAGGCAGCCGAGATGCTTTATGGATTGATCCACGCCCGCTACATCCTTACCAACCGTGGCATCGCCCAGATGTTG
GAAAAGTACCAGCAAGGAGACTTTGGTTACTGTCCTCGTGTGTACTGTGAGAACCAGCCAATGCTTCCCATTGGCCTTTCAGACATCCCA
GGTGAAGCCATGGTGAAGCTCTACTGCCCCAAGTGCATGGATGTGTACACACCCAAGTCATCAAGACACCATCACACGGATGGCGCCTAC
TTCGGCACTGGTTTCCCTCACATGCTCTTCATGGTGCATCCCGAGTACCGGCCCAAGAGACCTGCCAACCAGTTTGTGCCCAGGCTCTAC
GGTTTCAAGATCCATCCGATGGCCTACCAGCTGCAGCTCCAAGCCGCCAGCAACTTCAAGAGCCCAGTCAAGACGATTCGCTGATTCCCT
CCCCCACCTGTCCTGCAGTCTTTGACTTTTCCTTTCTTTTTTGCCACCCTTTCAGGAACCCTGTATGGTTTTTAGTTTAAATTAAAGGAG
TCGTTATCGTGGTGGGAATATGAAATAAAGTAGAAGAAAAGGCCATGAAAAAAAAAAAAAAACCGGAAATGGGTCCTACCATCTTCTCGG
AGCCGGAGTGCGAAGAAATAAAGAAATAGTGCTTTAAGTCAATGAATTCCTCCTTGGGACCCACTATCGAGAAACTATCAGTGGTAACGT
TTTAAAAAATGACAAATTCAATCTGCTCTTGACTTGTGTGTCCTAAGATTTCCACTAAGTGTCTTCAAACCTCCCCCTCCCCGGCTTCCT
GGATAATAGAAGTTCCCGAAGGCCGCCGATTCCAGAAGATACTGTCTGGCGTGAAATTAGTCTCAGTAGAAACATAAGTCCCGCGCGTCT
TGTGCTGCGCGTGCGCAAGCTTTTGGGCCCTCCCGAGAAAGGGAAGTGCATTCTCGCTTCCGTAGCGGTCTCCGCCGGTTGGGGGGAAGT
AATTCCGGTTGTTGCACCATGGCGTCCATGGGGACCCTCGCCTTCGATGAATATGGGCGCCCTTTCCTCATCATCAAGGATCAGGACCGC
AAGTCCCGTCTTATGGGACTTGAGGCCCTCAAGTCTCATATAATGGCAGCAAAGGCTGTAGCAAATACAATGAGAACATCACTTGGACCA
AATGGGCTTGATAAGATGATGGTGGATAAGGATGGAGATGTGACTGTAACTAATGATGGGGCCACCATCTTAAGCATGATGGATGTTGAT
CATCAGATTGCCAAGCTGATGGTGGAACTGTCCAAGTCTCAGGATGATGAAATTGGAGATGGAACCACAGGAGTGGTTGTCCTGGCTGGT
GCCTTGTTAGAAGAAGCGGAGCAATTGCTAGACCGAGGCATTCACCCAATCAGAATAGCCGATGGCTATGAGCAGGCTGCTCGTGTTGCT
ATTGAACACCTGGACAAGATCAGCGATAGCGTCCTTGTTGACATAAAGGACACCGAACCCCTGATTCAGACAGCAAAAACCACGCTGGGC
TCCAAAGTGGTCAACAGTTGTCACCGACAGATGGCTGAGATTGCTGTGAATGCCGTCCTCACTGTAGCAGATATGGAGCGGAGAGACGTT
GACTTTGAGCTTATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAGGACACTAAACTGATTAAGGGCGTGATTGTGGACAAGGATTTC
AGTCACCCACAGATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATTCTCACATGTCCATTTGAACCACCCAAACCAAAAACAAAGCAT
AAGCTGGATGTGACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATACGAAAAGGAGAAATTTGAAGAGATGATTCAACAAATTAAAGAG
ACTGGTGCTAACCTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCAAATCACTTACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGG
GTAGGAGGACCTGAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGGATCGTCCCCAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGC
TTTGCTGGTCTTGTACAGGAGATCTCATTTGGGACAACTAAGGATAAAATGCTGGTCATCGAGCAGTGTAAGAACTCCAGAGCTGTAACC
ATTTTTATTAGAGGAGGAAATAAGATGATCATTGAGGAGGCGAAACGATCCCTTCACGATGCTTTGTGTGTCATCCGGAACCTCATCCGC
GATAATCGTGTGGTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCCCTGGCAGTTAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAA
CAGTATGCCATGAGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATGGCCCTCTCTGAAAACAGTGGCATGAATCCCATCCAGACTATG
ACCGAAGTCCGAGCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGCATCGACTGTTTGCACAAGGGGACAAATGATATGAAGCAACAG
CATGTCATAGAAACCTTGATTGGCAAAAAGCAACAGATATCTCTTGCAACACAAATGGTTAGAATGATTTTGAAGATTGATGACATTCGT
AAGCCTGGAGAATCTGAAGAATGAAGACATTGAGAAAACTATGTAGCAAGATCCACTTCTGTGATTAAGTAAATGGATGTCTCGTGATGC
ATCTACAGTTATTTATTGTTACATCCTTTTCCAGACACTGTAGATGCTATAATAAAAATAGCTGTTTGGTAACCATAGTTTCACTTGTTC
AAAGCTGTGTAATCGTGGGGGTACCATCTCAACTGCTTTTGTATTCATTGTATTAAAAGAATCTGTTTAAACAACCTTTATCTTCTCTTC
GGGTTTAAGAAACGTTTATTGTAACAGTAATTAAATGCTGCCTTAATTGAAGGGGTTTGGGTGGATTTTTTTTTCTCAAAATAAGCTGTA
GGGACTATTTTAACAGCTTAAACAGGAGCTCTCAAGATGCACTTTCATATTGAGAGGAATATGGGCTTGATCCTCTTCCTATCTAAATGG
GTGGGCCATTTGATTGTAGAGGGTCCACCACAGAATTATGGGATGCCTTAAGTGCTGTTACTAGGTTGCTCACAGCCTAACCTGGCGTGT
TGTTTAGGGCTGATGGAGACCCATGTGAGCCTTTGCTTTCCTCTGGCCCCGGCCCCACCCTGAACACAGCTCATACACAGAATCAGGACC
AGCATGTGCAGAGCTGGCCACCAGCACAGGCTTAGGGCAGTTCAGAACCCACTTGTTTCCCTATCAGAGGGACACAGTGAAGTGGAGGTT
AAAGTAAATTACAGGAAATAAGGGAGAAATCTTGCAGTTACCATGTTCAGATAGAGTGACTGAAATTAATTGTACTTACTAAAGTATTAA
CTAGCTAACAGTGATGGGCCAAGACGCTCCGAGAACTCTACCGGGATTGTCTGTTCTGACAACCCAGTGAGGCAGATACACTTTCTTACT
GCTCACATCTTACAGGTGAGTACTCATAATTGGCCAGCATCTCACCACCAGCAAGTAGTAGGGCCAGGTCAATCCCAGGCAGTCTGACCC
CAGAGTGGCCCAGCTCATCCCCTACTCTGTTATTTGCTTGTTAATGATTCTCTAGATTTTCTAAAATAATGTTTCTTAGCATTGTGATGA
TAAAGCTCATGATGAACTTTATCACTAGTTATGCCACCTTAACTAGTCAGATTTCCTAGAATTAGGAAATGGTGACTCTTGTCTAAATTT
GGTTAAGTGATGAATTTGGGTTACCGTCTCATGTGAACCTGGAGATTCACCAGTCTTAACTTTTGGGTCATTGTGTTTTCTCTACATTCA
TGCATTGGATGTTTTGCTAAATAACTCCTGTGGATTTAGGAATGTGTGCTAATAGCAATCTTCCTAATTTTCATGTTTATATGGAACTAT
GCAGTTGAGTATTGAAAGCTTTAAACTGAGTTTATTTACAAGGACTGAGTCTAGCCTACAGAGAACATACAGCAGCCTTCTTTGGACCAC
AGTCTTATCCGAGGGGTCTGTGGTTGTATCAGAAGAGCCACTAAACCAATCCCCCTTTCCAAAATTGAACCTCACAGACGTTCCTGTTTT
TTGTGATTGAGAAACTGGTCAATGAACAGGAAGACTTAGAGATGTTTCACAAGCCTTTGATTTTTGTTTCATTTATTTGTAATAAACCTC

>19888_19888_3_CSNK2B-CCT5_CSNK2B_chr6_31637847_ENST00000375882_CCT5_chr5_10250033_ENST00000280326_length(amino acids)=551AA_BP=
MGGSNSGCCTMASMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSM
MDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAK
TTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKP
KTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTA
EKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKC
PTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKI

--------------------------------------------------------------
>19888_19888_4_CSNK2B-CCT5_CSNK2B_chr6_31637847_ENST00000375885_CCT5_chr5_10250033_ENST00000280326_length(transcript)=4736nt_BP=1061nt
CCCCACAATGCCCTTCGCCTTCCTCAACGTGGCCCCCGCTCCAAGCCCATTTTCTGGAGCCAGGAATCCACTCTGTGGGTTAGGAAAGGC
CCTCAGGAGGCGGAGGGAAACCTGTGGAATGCCGAGAAGCCGTGTAATGAAATAACGTCACGCCTGCCCCTCACCATTACTCTGACCAGG
GTTCGAAGGTCACACTTAGAGCCTAAGGGGAAATGGAGAAGTGCAAAGGGACGAGCAGAATGGCTGGCACCACCTCAGCTGACGTGAAGA
TGAGCAGCTCAGAGGAGGTGTCCTGGATTTCCTGGTTCTGTGGGCTCCGTGGCAATGAATTCTTCTGTGAAGTGGATGAAGACTACATCC
AGGACAAATTTAATCTTACTGGACTCAATGAGCAGGTCCCTCACTATCGACAAGCTCTAGACATGATCTTGGACCTGGAGCCTGATGAAG
AACTGGAAGACAACCCCAACCAGAGTGACCTGATTGAGCAGGCAGCCGAGATGCTTTATGGATTGATCCACGCCCGCTACATCCTTACCA
ACCGTGGCATCGCCCAGATGTTGGAAAAGTACCAGCAAGGAGACTTTGGTTACTGTCCTCGTGTGTACTGTGAGAACCAGCCAATGCTTC
CCATTGGCCTTTCAGACATCCCAGGTGAAGCCATGGTGAAGCTCTACTGCCCCAAGTGCATGGATGTGTACACACCCAAGTCATCAAGAC
ACCATCACACGGATGGCGCCTACTTCGGCACTGGTTTCCCTCACATGCTCTTCATGGTGCATCCCGAGTACCGGCCCAAGAGACCTGCCA
ACCAGTTTGTGCCCAGGCTCTACGGTTTCAAGATCCATCCGATGGCCTACCAGCTGCAGCTCCAAGCCGCCAGCAACTTCAAGAGCCCAG
TCAAGACGATTCGCTGATTCCCTCCCCCACCTGTCCTGCAGTCTTTGACTTTTCCTTTCTTTTTTGCCACCCTTTCAGGAACCCTGTATG
GTTTTTAGTTTAAATTAAAGGAGTCGTTATCGTGGTGGGAATATGAAATAAAGTAGAAGAAAAGGCCATGAAAAAAAAAAAAAAACCGGA
AATGGGTCCTACCATCTTCTCGGAGCCGGAGTGCGAAGAAATAAAGAAATAGTGCTTTAAGTCAATGAATTCCTCCTTGGGACCCACTAT
CGAGAAACTATCAGTGGTAACGTTTTAAAAAATGACAAATTCAATCTGCTCTTGACTTGTGTGTCCTAAGATTTCCACTAAGTGTCTTCA
AACCTCCCCCTCCCCGGCTTCCTGGATAATAGAAGTTCCCGAAGGCCGCCGATTCCAGAAGATACTGTCTGGCGTGAAATTAGTCTCAGT
AGAAACATAAGTCCCGCGCGTCTTGTGCTGCGCGTGCGCAAGCTTTTGGGCCCTCCCGAGAAAGGGAAGTGCATTCTCGCTTCCGTAGCG
GTCTCCGCCGGTTGGGGGGAAGTAATTCCGGTTGTTGCACCATGGCGTCCATGGGGACCCTCGCCTTCGATGAATATGGGCGCCCTTTCC
TCATCATCAAGGATCAGGACCGCAAGTCCCGTCTTATGGGACTTGAGGCCCTCAAGTCTCATATAATGGCAGCAAAGGCTGTAGCAAATA
CAATGAGAACATCACTTGGACCAAATGGGCTTGATAAGATGATGGTGGATAAGGATGGAGATGTGACTGTAACTAATGATGGGGCCACCA
TCTTAAGCATGATGGATGTTGATCATCAGATTGCCAAGCTGATGGTGGAACTGTCCAAGTCTCAGGATGATGAAATTGGAGATGGAACCA
CAGGAGTGGTTGTCCTGGCTGGTGCCTTGTTAGAAGAAGCGGAGCAATTGCTAGACCGAGGCATTCACCCAATCAGAATAGCCGATGGCT
ATGAGCAGGCTGCTCGTGTTGCTATTGAACACCTGGACAAGATCAGCGATAGCGTCCTTGTTGACATAAAGGACACCGAACCCCTGATTC
AGACAGCAAAAACCACGCTGGGCTCCAAAGTGGTCAACAGTTGTCACCGACAGATGGCTGAGATTGCTGTGAATGCCGTCCTCACTGTAG
CAGATATGGAGCGGAGAGACGTTGACTTTGAGCTTATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAGGACACTAAACTGATTAAGG
GCGTGATTGTGGACAAGGATTTCAGTCACCCACAGATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATTCTCACATGTCCATTTGAAC
CACCCAAACCAAAAACAAAGCATAAGCTGGATGTGACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATACGAAAAGGAGAAATTTGAAG
AGATGATTCAACAAATTAAAGAGACTGGTGCTAACCTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCAAATCACTTACTTCTTCAGA
ACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCTGAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGGATCGTCCCCAGGTTCTCAG
AGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTTGTACAGGAGATCTCATTTGGGACAACTAAGGATAAAATGCTGGTCATCGAGCAGT
GTAAGAACTCCAGAGCTGTAACCATTTTTATTAGAGGAGGAAATAAGATGATCATTGAGGAGGCGAAACGATCCCTTCACGATGCTTTGT
GTGTCATCCGGAACCTCATCCGCGATAATCGTGTGGTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCCCTGGCAGTTAGCCAAGAGG
CGGATAAGTGCCCCACCTTAGAACAGTATGCCATGAGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATGGCCCTCTCTGAAAACAGTG
GCATGAATCCCATCCAGACTATGACCGAAGTCCGAGCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGCATCGACTGTTTGCACAAGG
GGACAAATGATATGAAGCAACAGCATGTCATAGAAACCTTGATTGGCAAAAAGCAACAGATATCTCTTGCAACACAAATGGTTAGAATGA
TTTTGAAGATTGATGACATTCGTAAGCCTGGAGAATCTGAAGAATGAAGACATTGAGAAAACTATGTAGCAAGATCCACTTCTGTGATTA
AGTAAATGGATGTCTCGTGATGCATCTACAGTTATTTATTGTTACATCCTTTTCCAGACACTGTAGATGCTATAATAAAAATAGCTGTTT
GGTAACCATAGTTTCACTTGTTCAAAGCTGTGTAATCGTGGGGGTACCATCTCAACTGCTTTTGTATTCATTGTATTAAAAGAATCTGTT
TAAACAACCTTTATCTTCTCTTCGGGTTTAAGAAACGTTTATTGTAACAGTAATTAAATGCTGCCTTAATTGAAGGGGTTTGGGTGGATT
TTTTTTTCTCAAAATAAGCTGTAGGGACTATTTTAACAGCTTAAACAGGAGCTCTCAAGATGCACTTTCATATTGAGAGGAATATGGGCT
TGATCCTCTTCCTATCTAAATGGGTGGGCCATTTGATTGTAGAGGGTCCACCACAGAATTATGGGATGCCTTAAGTGCTGTTACTAGGTT
GCTCACAGCCTAACCTGGCGTGTTGTTTAGGGCTGATGGAGACCCATGTGAGCCTTTGCTTTCCTCTGGCCCCGGCCCCACCCTGAACAC
AGCTCATACACAGAATCAGGACCAGCATGTGCAGAGCTGGCCACCAGCACAGGCTTAGGGCAGTTCAGAACCCACTTGTTTCCCTATCAG
AGGGACACAGTGAAGTGGAGGTTAAAGTAAATTACAGGAAATAAGGGAGAAATCTTGCAGTTACCATGTTCAGATAGAGTGACTGAAATT
AATTGTACTTACTAAAGTATTAACTAGCTAACAGTGATGGGCCAAGACGCTCCGAGAACTCTACCGGGATTGTCTGTTCTGACAACCCAG
TGAGGCAGATACACTTTCTTACTGCTCACATCTTACAGGTGAGTACTCATAATTGGCCAGCATCTCACCACCAGCAAGTAGTAGGGCCAG
GTCAATCCCAGGCAGTCTGACCCCAGAGTGGCCCAGCTCATCCCCTACTCTGTTATTTGCTTGTTAATGATTCTCTAGATTTTCTAAAAT
AATGTTTCTTAGCATTGTGATGATAAAGCTCATGATGAACTTTATCACTAGTTATGCCACCTTAACTAGTCAGATTTCCTAGAATTAGGA
AATGGTGACTCTTGTCTAAATTTGGTTAAGTGATGAATTTGGGTTACCGTCTCATGTGAACCTGGAGATTCACCAGTCTTAACTTTTGGG
TCATTGTGTTTTCTCTACATTCATGCATTGGATGTTTTGCTAAATAACTCCTGTGGATTTAGGAATGTGTGCTAATAGCAATCTTCCTAA
TTTTCATGTTTATATGGAACTATGCAGTTGAGTATTGAAAGCTTTAAACTGAGTTTATTTACAAGGACTGAGTCTAGCCTACAGAGAACA
TACAGCAGCCTTCTTTGGACCACAGTCTTATCCGAGGGGTCTGTGGTTGTATCAGAAGAGCCACTAAACCAATCCCCCTTTCCAAAATTG
AACCTCACAGACGTTCCTGTTTTTTGTGATTGAGAAACTGGTCAATGAACAGGAAGACTTAGAGATGTTTCACAAGCCTTTGATTTTTGT

>19888_19888_4_CSNK2B-CCT5_CSNK2B_chr6_31637847_ENST00000375885_CCT5_chr5_10250033_ENST00000280326_length(amino acids)=551AA_BP=
MGGSNSGCCTMASMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSM
MDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAK
TTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKP
KTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTA
EKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKC
PTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKI

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for CSNK2B-CCT5

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Still interaction with
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000375865	-	7	7	188_193	264.0	216.0	alpha subunit
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000375866	-	7	7	188_193	264.0	216.0	alpha subunit
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000375882	-	7	7	188_193	264.0	216.0	alpha subunit

- Lost PPIs in in-frame fusion.

Partner	Gene	Hbp	Tbp	ENST	Strand	BPexon	TotalExon	Protein feature loci	*BPloci	TotalLen	Interaction lost with
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000383427	-	1	7	188_193	0	216.0	alpha subunit
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000383433	-	1	7	188_193	0	216.0	alpha subunit
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000400110	-	1	7	188_193	0	216.0	alpha subunit
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000412802	-	1	7	188_193	0	216.0	alpha subunit
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000418230	-	1	7	188_193	0	216.0	alpha subunit
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000422567	-	1	7	188_193	0	216.0	alpha subunit
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000429633	-	1	7	188_193	0	216.0	alpha subunit
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000431476	-	1	7	188_193	0	216.0	alpha subunit
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000436169	-	1	7	188_193	0	216.0	alpha subunit
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000443673	-	1	7	188_193	0	216.0	alpha subunit
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000448596	-	1	7	188_193	0	216.0	alpha subunit
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000451917	-	1	7	188_193	0	216.0	alpha subunit
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000452985	-	1	7	188_193	0	216.0	alpha subunit
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000453234	-	1	7	188_193	0	216.0	alpha subunit
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000454382	-	1	7	188_193	0	216.0	alpha subunit
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000454511	-	1	7	188_193	0	216.0	alpha subunit
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000455161	-	1	7	188_193	0	216.0	alpha subunit
Hgene	CSNK2B	chr6:31637847	chr5:10250033	ENST00000458330	-	1	7	188_193	0	216.0	alpha subunit

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for CSNK2B-CCT5

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for CSNK2B-CCT5

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source