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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:CSPG4-SON (FusionGDB2 ID:19903) |
Fusion Gene Summary for CSPG4-SON |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CSPG4-SON | Fusion gene ID: 19903 | Hgene | Tgene | Gene symbol | CSPG4 | SON | Gene ID | 1464 | 6651 |
| Gene name | chondroitin sulfate proteoglycan 4 | SON DNA and RNA binding protein | |
| Synonyms | HMW-MAA|MCSP|MCSPG|MEL-CSPG|MSK16|NG2 | BASS1|C21orf50|DBP-5|NREBP|SON3|TOKIMS | |
| Cytomap | 15q24.2 | 21q22.11 | |
| Type of gene | protein-coding | protein-coding | |
| Description | chondroitin sulfate proteoglycan 4chondroitin sulfate proteoglycan 4 (melanoma-associated)chondroitin sulfate proteoglycan NG2melanoma chondroitin sulfate proteoglycanmelanoma-associated chondroitin sulfate proteoglycan | protein SONBax antagonist selected in Saccharomyces 1NRE-binding proteinSON DNA binding proteinnegative regulatory element-binding protein | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | Q6UVK1 | SHH | |
| Ensembl transtripts involved in fusion gene | ENST00000308508, | ENST00000470533, ENST00000300278, ENST00000381679, ENST00000290239, ENST00000356577, ENST00000381692, | |
| Fusion gene scores | * DoF score | 5 X 4 X 3=60 | 16 X 15 X 5=1200 |
| # samples | 5 | 16 | |
| ** MAII score | log2(5/60*10)=-0.263034405833794 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(16/1200*10)=-2.90689059560852 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CSPG4 [Title/Abstract] AND SON [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | CSPG4(75977076)-SON(34945612), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | CSPG4 | GO:0035556 | intracellular signal transduction | 10587647 |
| Hgene | CSPG4 | GO:0050731 | positive regulation of peptidyl-tyrosine phosphorylation | 10587647 |
| Tgene | SON | GO:0006397 | mRNA processing | 21504830 |
| Tgene | SON | GO:0043066 | negative regulation of apoptotic process | 10509013 |
| Tgene | SON | GO:0048024 | regulation of mRNA splicing, via spliceosome | 21504830 |
| Fusion gene breakpoints across CSPG4 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across SON (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChiTaRS5.0 | N/A | CD172355 | CSPG4 | chr15 | 75977076 | - | SON | chr21 | 34945612 | + |
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Fusion Gene ORF analysis for CSPG4-SON |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-3UTR | ENST00000308508 | ENST00000470533 | CSPG4 | chr15 | 75977076 | - | SON | chr21 | 34945612 | + |
| 5CDS-intron | ENST00000308508 | ENST00000300278 | CSPG4 | chr15 | 75977076 | - | SON | chr21 | 34945612 | + |
| 5CDS-intron | ENST00000308508 | ENST00000381679 | CSPG4 | chr15 | 75977076 | - | SON | chr21 | 34945612 | + |
| In-frame | ENST00000308508 | ENST00000290239 | CSPG4 | chr15 | 75977076 | - | SON | chr21 | 34945612 | + |
| In-frame | ENST00000308508 | ENST00000356577 | CSPG4 | chr15 | 75977076 | - | SON | chr21 | 34945612 | + |
| In-frame | ENST00000308508 | ENST00000381692 | CSPG4 | chr15 | 75977076 | - | SON | chr21 | 34945612 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000308508 | CSPG4 | chr15 | 75977076 | - | ENST00000356577 | SON | chr21 | 34945612 | + | 5995 | 4542 | 93 | 4937 | 1614 |
| ENST00000308508 | CSPG4 | chr15 | 75977076 | - | ENST00000290239 | SON | chr21 | 34945612 | + | 6020 | 4542 | 93 | 4937 | 1614 |
| ENST00000308508 | CSPG4 | chr15 | 75977076 | - | ENST00000381692 | SON | chr21 | 34945612 | + | 5995 | 4542 | 93 | 4937 | 1614 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000308508 | ENST00000356577 | CSPG4 | chr15 | 75977076 | - | SON | chr21 | 34945612 | + | 0.00126061 | 0.9987394 |
| ENST00000308508 | ENST00000290239 | CSPG4 | chr15 | 75977076 | - | SON | chr21 | 34945612 | + | 0.001214538 | 0.99878544 |
| ENST00000308508 | ENST00000381692 | CSPG4 | chr15 | 75977076 | - | SON | chr21 | 34945612 | + | 0.00126061 | 0.9987394 |
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Fusion Genomic Features for CSPG4-SON |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| CSPG4 | chr15 | 75977076 | - | SON | chr21 | 34945613 | + | 0.011987235 | 0.9880128 |
| CSPG4 | chr15 | 75977076 | - | SON | chr21 | 34945613 | + | 0.011987235 | 0.9880128 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for CSPG4-SON |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:75977076/chr21:34945612) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CSPG4 | SON |
| FUNCTION: Proteoglycan playing a role in cell proliferation and migration which stimulates endothelial cells motility during microvascular morphogenesis. May also inhibit neurite outgrowth and growth cone collapse during axon regeneration. Cell surface receptor for collagen alpha 2(VI) which may confer cells ability to migrate on that substrate. Binds through its extracellular N-terminus growth factors, extracellular matrix proteases modulating their activity. May regulate MPP16-dependent degradation and invasion of type I collagen participating in melanoma cells invasion properties. May modulate the plasminogen system by enhancing plasminogen activation and inhibiting angiostatin. Functions also as a signal transducing protein by binding through its cytoplasmic C-terminus scaffolding and signaling proteins. May promote retraction fiber formation and cell polarization through Rho GTPase activation. May stimulate alpha-4, beta-1 integrin-mediated adhesion and spreading by recruiting and activating a signaling cascade through CDC42, ACK1 and BCAR1. May activate FAK and ERK1/ERK2 signaling cascades. {ECO:0000269|PubMed:10587647, ECO:0000269|PubMed:11278606, ECO:0000269|PubMed:15210734}. | 462 |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 202_380 | 1483 | 2323.0 | Domain | Laminin G-like 2 |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 30_192 | 1483 | 2323.0 | Domain | Laminin G-like 1 |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 30_639 | 1483 | 2323.0 | Region | Neurite growth inhibition |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 1018_1110 | 1483 | 2323.0 | Repeat | CSPG 6 |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 1126_1216 | 1483 | 2323.0 | Repeat | CSPG 7 |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 1238_1337 | 1483 | 2323.0 | Repeat | CSPG 8 |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 1356_1449 | 1483 | 2323.0 | Repeat | CSPG 9 |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 428_523 | 1483 | 2323.0 | Repeat | CSPG 1 |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 553_645 | 1483 | 2323.0 | Repeat | CSPG 2 |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 662_764 | 1483 | 2323.0 | Repeat | CSPG 3 |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 783_878 | 1483 | 2323.0 | Repeat | CSPG 4 |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 898_989 | 1483 | 2323.0 | Repeat | CSPG 5 |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 2371_2426 | 2321 | 699.6666666666666 | Domain | DRBM | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 2305_2351 | 0 | 2304.0 | Domain | G-patch | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 2371_2426 | 0 | 2304.0 | Domain | DRBM | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 2305_2351 | 2295 | 2427.0 | Domain | G-patch | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 2371_2426 | 2295 | 2427.0 | Domain | DRBM | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 2305_2351 | 0 | 2109.0 | Domain | G-patch | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 2371_2426 | 0 | 2109.0 | Domain | DRBM | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1006_1126 | 0 | 2304.0 | Region | Note=14 X 6 AA repeats of [ED]-R-S-M-M-S | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1147_1179 | 0 | 2304.0 | Region | Note=3 X 11 AA tandem repats of P-P-L-P-P-E-E-P-P-[TME]-[MTG] | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1359_1390 | 0 | 2304.0 | Region | Note=4 X 8 AA tandem repeats of V-L-E-SS-[AVT]-VT | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1925_1994 | 0 | 2304.0 | Region | Note=7 X 7 AA repeats of P-S-R-R-S-R-[TS] | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1934_2013 | 0 | 2304.0 | Region | Note=2 X 19 AA repeats of P-S-R-R-R-R-S-R-S-V-V-R-R-R-S-F-S-I-S | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 2013_2039 | 0 | 2304.0 | Region | Note=3 X tandem repeats of [ST]-P-[VLI]-R-[RL]-[RK]-[RF]-S-R | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 726_895 | 0 | 2304.0 | Region | Note=17 X 10 AA tandem repeats of L-A-[ST]-[NSG]-[TS]-MDSQM | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 912_988 | 0 | 2304.0 | Region | Note=11 X 7 AA tandem repeats of [DR]-P-Y-R-[LI][AG][QHP] | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1006_1126 | 0 | 2109.0 | Region | Note=14 X 6 AA repeats of [ED]-R-S-M-M-S | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1147_1179 | 0 | 2109.0 | Region | Note=3 X 11 AA tandem repats of P-P-L-P-P-E-E-P-P-[TME]-[MTG] | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1359_1390 | 0 | 2109.0 | Region | Note=4 X 8 AA tandem repeats of V-L-E-SS-[AVT]-VT | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1925_1994 | 0 | 2109.0 | Region | Note=7 X 7 AA repeats of P-S-R-R-S-R-[TS] | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1934_2013 | 0 | 2109.0 | Region | Note=2 X 19 AA repeats of P-S-R-R-R-R-S-R-S-V-V-R-R-R-S-F-S-I-S | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 2013_2039 | 0 | 2109.0 | Region | Note=3 X tandem repeats of [ST]-P-[VLI]-R-[RL]-[RK]-[RF]-S-R | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 726_895 | 0 | 2109.0 | Region | Note=17 X 10 AA tandem repeats of L-A-[ST]-[NSG]-[TS]-MDSQM | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 912_988 | 0 | 2109.0 | Region | Note=11 X 7 AA tandem repeats of [DR]-P-Y-R-[LI][AG][QHP] | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1006_1011 | 0 | 2304.0 | Repeat | Note=1-1 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1014_1019 | 0 | 2304.0 | Repeat | Note=1-2 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1021_1026 | 0 | 2304.0 | Repeat | Note=1-3 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1030_1035 | 0 | 2304.0 | Repeat | Note=1-4 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1038_1043 | 0 | 2304.0 | Repeat | Note=1-5 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1046_1051 | 0 | 2304.0 | Repeat | Note=1-6 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1055_1060 | 0 | 2304.0 | Repeat | Note=1-7 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1063_1068 | 0 | 2304.0 | Repeat | Note=1-8 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1071_1076 | 0 | 2304.0 | Repeat | Note=1-9 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1080_1085 | 0 | 2304.0 | Repeat | Note=1-10 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1089_1094 | 0 | 2304.0 | Repeat | Note=1-11 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1100_1105 | 0 | 2304.0 | Repeat | Note=1-12 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1111_1116 | 0 | 2304.0 | Repeat | Note=1-13 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1121_1126 | 0 | 2304.0 | Repeat | Note=1-14 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1925_1931 | 0 | 2304.0 | Repeat | Note=2-1 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1934_1952 | 0 | 2304.0 | Repeat | Note=3-1 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1953_1959 | 0 | 2304.0 | Repeat | Note=2-2 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1960_1966 | 0 | 2304.0 | Repeat | Note=2-3 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1967_1973 | 0 | 2304.0 | Repeat | Note=2-4 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1974_1980 | 0 | 2304.0 | Repeat | Note=2-5 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1981_1987 | 0 | 2304.0 | Repeat | Note=2-6 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1988_1994 | 0 | 2304.0 | Repeat | Note=2-7 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000300278 | 0 | 7 | 1995_2013 | 0 | 2304.0 | Repeat | Note=3-2 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1006_1011 | 0 | 2109.0 | Repeat | Note=1-1 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1014_1019 | 0 | 2109.0 | Repeat | Note=1-2 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1021_1026 | 0 | 2109.0 | Repeat | Note=1-3 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1030_1035 | 0 | 2109.0 | Repeat | Note=1-4 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1038_1043 | 0 | 2109.0 | Repeat | Note=1-5 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1046_1051 | 0 | 2109.0 | Repeat | Note=1-6 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1055_1060 | 0 | 2109.0 | Repeat | Note=1-7 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1063_1068 | 0 | 2109.0 | Repeat | Note=1-8 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1071_1076 | 0 | 2109.0 | Repeat | Note=1-9 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1080_1085 | 0 | 2109.0 | Repeat | Note=1-10 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1089_1094 | 0 | 2109.0 | Repeat | Note=1-11 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1100_1105 | 0 | 2109.0 | Repeat | Note=1-12 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1111_1116 | 0 | 2109.0 | Repeat | Note=1-13 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1121_1126 | 0 | 2109.0 | Repeat | Note=1-14 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1925_1931 | 0 | 2109.0 | Repeat | Note=2-1 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1934_1952 | 0 | 2109.0 | Repeat | Note=3-1 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1953_1959 | 0 | 2109.0 | Repeat | Note=2-2 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1960_1966 | 0 | 2109.0 | Repeat | Note=2-3 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1967_1973 | 0 | 2109.0 | Repeat | Note=2-4 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1974_1980 | 0 | 2109.0 | Repeat | Note=2-5 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1981_1987 | 0 | 2109.0 | Repeat | Note=2-6 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1988_1994 | 0 | 2109.0 | Repeat | Note=2-7 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000381679 | 0 | 5 | 1995_2013 | 0 | 2109.0 | Repeat | Note=3-2 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 639_1586 | 1483 | 2323.0 | Compositional bias | Note=Gly/Ser-rich (glycosaminoglycan attachment domain) |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 2320_2322 | 1483 | 2323.0 | Motif | Note=PDZ-binding |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 1586_2221 | 1483 | 2323.0 | Region | Neurite growth inhibition |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 1587_2221 | 1483 | 2323.0 | Region | Note=Cysteine-containing |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 1473_1563 | 1483 | 2323.0 | Repeat | CSPG 10 |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 1581_1679 | 1483 | 2323.0 | Repeat | CSPG 11 |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 1704_1803 | 1483 | 2323.0 | Repeat | CSPG 12 |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 1832_1924 | 1483 | 2323.0 | Repeat | CSPG 13 |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 1941_2029 | 1483 | 2323.0 | Repeat | CSPG 14 |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 2038_2147 | 1483 | 2323.0 | Repeat | CSPG 15 |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 2246_2322 | 1483 | 2323.0 | Topological domain | Cytoplasmic |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 30_2224 | 1483 | 2323.0 | Topological domain | Extracellular |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 2225_2245 | 1483 | 2323.0 | Transmembrane | Helical |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 2305_2351 | 2321 | 699.6666666666666 | Domain | G-patch | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1006_1126 | 2321 | 699.6666666666666 | Region | Note=14 X 6 AA repeats of [ED]-R-S-M-M-S | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1147_1179 | 2321 | 699.6666666666666 | Region | Note=3 X 11 AA tandem repats of P-P-L-P-P-E-E-P-P-[TME]-[MTG] | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1359_1390 | 2321 | 699.6666666666666 | Region | Note=4 X 8 AA tandem repeats of V-L-E-SS-[AVT]-VT | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1925_1994 | 2321 | 699.6666666666666 | Region | Note=7 X 7 AA repeats of P-S-R-R-S-R-[TS] | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1934_2013 | 2321 | 699.6666666666666 | Region | Note=2 X 19 AA repeats of P-S-R-R-R-R-S-R-S-V-V-R-R-R-S-F-S-I-S | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 2013_2039 | 2321 | 699.6666666666666 | Region | Note=3 X tandem repeats of [ST]-P-[VLI]-R-[RL]-[RK]-[RF]-S-R | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 726_895 | 2321 | 699.6666666666666 | Region | Note=17 X 10 AA tandem repeats of L-A-[ST]-[NSG]-[TS]-MDSQM | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 912_988 | 2321 | 699.6666666666666 | Region | Note=11 X 7 AA tandem repeats of [DR]-P-Y-R-[LI][AG][QHP] | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1006_1126 | 2295 | 2427.0 | Region | Note=14 X 6 AA repeats of [ED]-R-S-M-M-S | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1147_1179 | 2295 | 2427.0 | Region | Note=3 X 11 AA tandem repats of P-P-L-P-P-E-E-P-P-[TME]-[MTG] | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1359_1390 | 2295 | 2427.0 | Region | Note=4 X 8 AA tandem repeats of V-L-E-SS-[AVT]-VT | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1925_1994 | 2295 | 2427.0 | Region | Note=7 X 7 AA repeats of P-S-R-R-S-R-[TS] | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1934_2013 | 2295 | 2427.0 | Region | Note=2 X 19 AA repeats of P-S-R-R-R-R-S-R-S-V-V-R-R-R-S-F-S-I-S | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 2013_2039 | 2295 | 2427.0 | Region | Note=3 X tandem repeats of [ST]-P-[VLI]-R-[RL]-[RK]-[RF]-S-R | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 726_895 | 2295 | 2427.0 | Region | Note=17 X 10 AA tandem repeats of L-A-[ST]-[NSG]-[TS]-MDSQM | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 912_988 | 2295 | 2427.0 | Region | Note=11 X 7 AA tandem repeats of [DR]-P-Y-R-[LI][AG][QHP] | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1006_1011 | 2321 | 699.6666666666666 | Repeat | Note=1-1 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1014_1019 | 2321 | 699.6666666666666 | Repeat | Note=1-2 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1021_1026 | 2321 | 699.6666666666666 | Repeat | Note=1-3 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1030_1035 | 2321 | 699.6666666666666 | Repeat | Note=1-4 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1038_1043 | 2321 | 699.6666666666666 | Repeat | Note=1-5 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1046_1051 | 2321 | 699.6666666666666 | Repeat | Note=1-6 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1055_1060 | 2321 | 699.6666666666666 | Repeat | Note=1-7 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1063_1068 | 2321 | 699.6666666666666 | Repeat | Note=1-8 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1071_1076 | 2321 | 699.6666666666666 | Repeat | Note=1-9 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1080_1085 | 2321 | 699.6666666666666 | Repeat | Note=1-10 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1089_1094 | 2321 | 699.6666666666666 | Repeat | Note=1-11 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1100_1105 | 2321 | 699.6666666666666 | Repeat | Note=1-12 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1111_1116 | 2321 | 699.6666666666666 | Repeat | Note=1-13 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1121_1126 | 2321 | 699.6666666666666 | Repeat | Note=1-14 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1925_1931 | 2321 | 699.6666666666666 | Repeat | Note=2-1 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1934_1952 | 2321 | 699.6666666666666 | Repeat | Note=3-1 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1953_1959 | 2321 | 699.6666666666666 | Repeat | Note=2-2 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1960_1966 | 2321 | 699.6666666666666 | Repeat | Note=2-3 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1967_1973 | 2321 | 699.6666666666666 | Repeat | Note=2-4 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1974_1980 | 2321 | 699.6666666666666 | Repeat | Note=2-5 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1981_1987 | 2321 | 699.6666666666666 | Repeat | Note=2-6 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1988_1994 | 2321 | 699.6666666666666 | Repeat | Note=2-7 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000290239 | 8 | 13 | 1995_2013 | 2321 | 699.6666666666666 | Repeat | Note=3-2 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1006_1011 | 2295 | 2427.0 | Repeat | Note=1-1 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1014_1019 | 2295 | 2427.0 | Repeat | Note=1-2 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1021_1026 | 2295 | 2427.0 | Repeat | Note=1-3 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1030_1035 | 2295 | 2427.0 | Repeat | Note=1-4 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1038_1043 | 2295 | 2427.0 | Repeat | Note=1-5 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1046_1051 | 2295 | 2427.0 | Repeat | Note=1-6 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1055_1060 | 2295 | 2427.0 | Repeat | Note=1-7 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1063_1068 | 2295 | 2427.0 | Repeat | Note=1-8 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1071_1076 | 2295 | 2427.0 | Repeat | Note=1-9 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1080_1085 | 2295 | 2427.0 | Repeat | Note=1-10 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1089_1094 | 2295 | 2427.0 | Repeat | Note=1-11 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1100_1105 | 2295 | 2427.0 | Repeat | Note=1-12 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1111_1116 | 2295 | 2427.0 | Repeat | Note=1-13 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1121_1126 | 2295 | 2427.0 | Repeat | Note=1-14 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1925_1931 | 2295 | 2427.0 | Repeat | Note=2-1 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1934_1952 | 2295 | 2427.0 | Repeat | Note=3-1 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1953_1959 | 2295 | 2427.0 | Repeat | Note=2-2 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1960_1966 | 2295 | 2427.0 | Repeat | Note=2-3 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1967_1973 | 2295 | 2427.0 | Repeat | Note=2-4 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1974_1980 | 2295 | 2427.0 | Repeat | Note=2-5 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1981_1987 | 2295 | 2427.0 | Repeat | Note=2-6 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1988_1994 | 2295 | 2427.0 | Repeat | Note=2-7 | |
| Tgene | SON | chr15:75977076 | chr21:34945612 | ENST00000356577 | 7 | 12 | 1995_2013 | 2295 | 2427.0 | Repeat | Note=3-2 |
Top |
Fusion Gene Sequence for CSPG4-SON |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >19903_19903_1_CSPG4-SON_CSPG4_chr15_75977076_ENST00000308508_SON_chr21_34945612_ENST00000290239_length(transcript)=6020nt_BP=4542nt GCGCCCAGGAGCAGAGCCGCGCTCGCTCCACTCAGCTCCCAGCTCCCAGGACTCCGCTGGCTCCTCGCAAGTCCTGCCGCCCAGCCCGCC GGGATGCAGTCCGGGCCGCGGCCCCCACTTCCAGCCCCCGGCCTGGCCTTGGCTTTGACCCTGACTATGTTGGCCAGACTTGCATCCGCG GCTTCCTTCTTCGGTGAGAACCACCTGGAGGTGCCTGTGGCCACGGCTCTGACCGACATAGACCTGCAGCTGCAGTTCTCCACGTCCCAG CCCGAAGCCCTCCTTCTCCTGGCAGCAGGCCCAGCTGACCACCTCCTGCTGCAGCTCTACTCTGGACGCCTGCAGGTCAGACTTGTTCTG GGCCAGGAGGAGCTGAGGCTGCAGACTCCAGCAGAGACGCTGCTGAGTGACTCCATCCCCCACACTGTGGTGCTGACTGTCGTAGAGGGC TGGGCCACGTTGTCAGTCGATGGGTTTCTGAACGCCTCCTCAGCAGTCCCAGGAGCCCCCCTAGAGGTCCCCTATGGGCTCTTTGTTGGG GGCACTGGGACCCTTGGCCTGCCCTACCTGAGGGGAACCAGCCGACCCCTGAGGGGTTGCCTCCATGCAGCCACCCTCAATGGCCGCAGC CTCCTCCGGCCTCTGACCCCCGATGTGCATGAGGGCTGTGCTGAAGAGTTTTCTGCCAGTGATGATGTGGCCCTGGGCTTCTCTGGGCCC CACTCTCTGGCTGCCTTCCCTGCCTGGGGCACTCAGGACGAAGGAACCCTAGAGTTTACACTCACCACACAGAGCCGGCAGGCACCCTTG GCCTTCCAGGCAGGGGGCCGGCGTGGGGACTTCATCTATGTGGACATATTTGAGGGCCACCTGCGGGCCGTGGTGGAGAAGGGCCAGGGT ACCGTATTGCTCCACAACAGTGTGCCTGTGGCCGATGGGCAGCCCCATGAGGTCAGTGTCCACATCAATGCTCACCGGCTGGAAATCTCC GTGGACCAGTACCCTACGCATACTTCGAACCGAGGAGTCCTCAGCTACCTGGAGCCACGGGGCAGTCTCCTTCTCGGGGGGCTGGATGCA GAGGCCTCTCGTCACCTCCAGGAACACCGCCTGGGCCTGACACCAGAGGCCACCAATGCCTCCCTGCTGGGCTGCATGGAAGACCTCAGT GTCAATGGCCAGAGGCGGGGGCTGCGGGAAGCTTTGCTGACGCGCAACATGGCAGCCGGCTGCAGGCTGGAGGAGGAGGAGTATGAGGAC GATGCCTATGGACATTATGAAGCTTTCTCCACCCTGGCCCCTGAGGCTTGGCCAGCCATGGAGCTGCCTGAGCCATGCGTGCCTGAGCCA GGGCTGCCTCCTGTCTTTGCCAATTTCACCCAGCTGCTGACTATCAGCCCACTGGTGGTGGCCGAGGGGGGCACAGCCTGGCTTGAGTGG AGGCATGTGCAGCCCACGCTGGACCTGATGGAGGCTGAGCTGCGCAAATCCCAGGTGCTGTTCAGCGTGACCCGAGGGGCACGCCATGGC GAGCTCGAGCTGGACATCCCGGGAGCCCAGGCACGAAAAATGTTCACCCTCCTGGACGTGGTGAACCGCAAGGCCCGCTTCATCCACGAT GGCTCTGAGGACACCTCCGACCAGCTGGTGCTGGAGGTGTCGGTGACGGCTCGGGTGCCCATGCCCTCATGCCTTCGGAGGGGCCAAACA TACCTCCTGCCCATCCAGGTCAACCCTGTCAATGACCCACCCCACATCATCTTCCCACATGGCAGCCTCATGGTGATCCTGGAACACACG CAGAAGCCGCTGGGGCCTGAGGTTTTCCAGGCCTATGACCCGGACTCTGCCTGTGAGGGCCTCACCTTCCAGGTCCTTGGCACCTCCTCT GGCCTCCCCGTGGAGCGCCGAGACCAGCCTGGGGAGCCGGCGACCGAGTTCTCCTGCCGGGAGTTGGAGGCCGGCAGCCTAGTCTATGTC CACCGCGGTGGTCCTGCACAGGACTTGACGTTCCGGGTCAGCGATGGACTGCAGGCCAGCCCCCCGGCCACGCTGAAGGTGGTGGCCATC CGGCCGGCCATACAGATCCACCGCAGCACAGGGTTGCGACTGGCCCAAGGCTCTGCCATGCCCATCTTGCCCGCCAACCTGTCGGTGGAG ACCAATGCCGTGGGGCAGGATGTGAGCGTGCTGTTCCGCGTCACTGGGGCCCTGCAGTTTGGGGAGCTGCAGAAGCAGGGGGCAGGTGGG GTGGAGGGTGCTGAGTGGTGGGCCACACAGGCGTTCCACCAGCGGGATGTGGAGCAGGGCCGCGTGAGGTACCTGAGCACTGACCCACAG CACCACGCTTACGACACCGTGGAGAACCTGGCCCTGGAGGTGCAGGTGGGCCAGGAGATCCTGAGCAATCTGTCCTTCCCAGTGACCATC CAGAGAGCCACTGTGTGGATGCTGCGGCTGGAGCCACTGCACACTCAGAACACCCAGCAGGAGACCCTCACCACAGCCCACCTGGAGGCC ACCCTGGAGGAGGCAGGCCCAAGCCCCCCAACCTTCCATTATGAGGTGGTTCAGGCTCCCAGGAAAGGCAACCTTCAACTACAGGGCACA AGGCTGTCAGATGGCCAGGGCTTCACCCAGGATGACATACAGGCTGGCCGGGTGACCTATGGGGCCACAGCACGTGCCTCAGAGGCAGTC GAGGACACCTTCCGTTTCCGTGTCACAGCTCCACCATATTTCTCCCCACTCTATACCTTCCCCATCCACATTGGTGGTGACCCAGATGCG CCTGTCCTCACCAATGTCCTCCTCGTGGTGCCTGAGGGTGGTGAGGGTGTCCTCTCTGCTGACCACCTCTTTGTCAAGAGTCTCAACAGT GCCAGCTACCTCTATGAGGTCATGGAGCGGCCCCGCCATGGGAGGTTGGCTTGGCGTGGGACACAGGACAAGACCACTATGGTGACATCC TTCACCAATGAAGACCTGTTGCGTGGCCGGCTGGTCTACCAGCATGATGACTCCGAGACCACAGAAGATGATATCCCATTTGTTGCTACC CGCCAGGGCGAGAGCAGTGGTGACATGGCCTGGGAGGAGGTACGGGGTGTCTTCCGAGTGGCCATCCAGCCCGTGAATGACCACGCCCCT GTGCAGACCATCAGCCGGATCTTCCATGTGGCCCGGGGTGGGCGGCGGCTGCTGACTACAGACGACGTGGCCTTCAGCGATGCTGACTCG GGCTTTGCTGACGCCCAGCTGGTGCTTACCCGCAAGGACCTCCTCTTTGGCAGTATCGTGGCCGTAGATGAGCCCACGCGGCCCATCTAC CGCTTCACCCAGGAGGACCTCAGGAAGAGGCGAGTACTGTTCGTGCACTCAGGGGCTGACCGTGGCTGGATCCAGCTGCAGGTGTCCGAC GGGCAACACCAGGCCACTGCGCTGCTGGAGGTGCAGGCCTCGGAACCCTACCTCCGTGTGGCCAACGGCTCCAGCCTTGTGGTCCCTCAA GGAGGCCAGGGCACCATCGACACGGCCGTGCTCCACCTGGACACCAACCTCGACATCCGCAGTGGGGATGAGGTCCACTACCACGTCACA GCTGGCCCTCGCTGGGGACAGCTAGTCCGGGCTGGTCAGCCAGCCACAGCCTTCTCCCAGCAGGACCTGCTGGATGGGGCCGTTCTCTAT AGCCACAATGGCAGCCTCAGCCCCCGCGACACCATGGCCTTCTCCGTGGAAGCAGGGCCAGTGCACACGGATGCCACCCTACAAGTGACC ATTGCCCTAGAGGGCCCACTGGCCCCACTGAAGCTGGTCCGGCACAAGAAGATCTACGTCTTCCAGGGAGAGGCAGCTGAGATCAGAAGG GACCAGCTGGAGGCAGCCCAGGAGGCAGTGCCACCTGCAGACATCGTATTCTCAGTGAAGAGCCCACCGAGTGCCGGCTACCTGGTGATG GTGTCGCGTGGCGCCTTGGCAGATGAGCCACCCAGCCTGGACCCTGTGCAGAGCTTCTCCCAGGAGGCAGTGGACACAGGCAGGGTCCTG TACCTGCACTCCCGCCCTGAGGCCTGGAGCGATGCCTTCTCGCTGGATGTGGCCTCAGGCCTGGGTGCTCCCCTCGAGGGCGTCCTTGTG GAGCTGGAGGTGCTGCCCGCTGCCATCCCACTAGAGGCGCAAAACTTCAGCGTCCCTGAGGGTGGCAGCCTCACCCTGGCCCCTCCACTG CTCCGTGTCTCCGGGCCCTACTTCCCCACTCTCCTGGGCCTCAGCCTGCAGGTGCTGGAGCCACCCCAGCATGGAGCCCTGCAGAAGGAG GACGGACCTCAAGCCAGGACCCTCAGCGCCTTCTCCTGGAGAATGGTGGAAGAGCAGCTGATCCGCTACGTGCATGACGGGAGCGAGACA CTGACAGACAGTTTTGTCCTGATGGCTAATGCCTCCGAGATGGATCGCCAGAGCCATCCTGTGGCCTTCACTGTCACTGTCCTGCCTGTC AATGACCAACCCCCCATCCTCACTACAAACACAGGCCTGCAGGATCAGTTCTTAAGAGCAGCCCCGGTAACTGGAGGAATGGGAGCCGTT TTGATGAGAAAAATGGGCTGGAGAGAAGGAGAAGGATTAGGAAAAAACAAAGAAGGCAATAAGGAACCCATCCTAGTTGATTTTAAGACA GACCGAAAAGGTCTTGTTGCAGTAGGAGAAAGAGCACAAAAGAGGTCTGGGAACTTCTCTGCTGCAATGAAAGATCTGTCAGGCAAACAT CCTGTGTCTGCTTTGATGGAGATCTGTAATAAAAGAAGGTGGCAACCACCTGAATTTCTATTGGTCCATGATAGTGGCCCTGATCATCGC AAACATTTTCTCTTTAGGGTATTGAGAAATGGAGCCCTTACCAGACCCAATTGTATGTTTTTCTTGAATAGGTATTGATAAATGGAAGCG CTTACCAGCCCAGCTTTGCCAGCCCTAATAAGAAGCATGCTAAAGCCACAGCAGCTACTGTGGTTCTTCAAGCAATGGGCCTTGTACCAA AGGACCTCATGGCTAATGCCACTTGCTTCAGGAGTGCCTCACGTAGATAGATTGAGGTTTTATAATAATCATTTCAGAATTTTACTCTGC ATCACAATGTATTTCCTCTTTAATGTTGTAAATATTTGGCAATTTAAGACATTGTGTAAAAAGCAATCTGTAAAAACATCTCCAGGCTTT GATTTTTGTACCATGGAAATTGTATTTAACCATACAGGGTTTTGGTATGTTTATATTGTTTACCTTAGTGATGTATTTGTTTAAGTGGCT AACATCCAAACGACTGTTTGAAGGCATCAGAGTAATCTTCAGTGTGGAATGTTAAATAACGCTTTTATACTGTATTTTGTACTATGATGT AACTCCCCTTCCTTATGGCTAGGCTACTGTAACACTTGCCTGTAATCAGTGAAGGGCTGTGCACCTTGTACTATTTCACAATGGGTTCTG CTGGACAGATAATGGGCCAGTGTTATTGAGGTGATCAAGATCTGTTCCACAGGGCTAATGCCACCATCTCCCCTCAAAATTTTGTAGAGG TTCTAAAAAGAAAGTGGTATGTTGTGTGATGATCAGCACTAAGTCCTGCATTCCTGTTAAAGCCACTTGGGTCATAAGAAGGGAGTAAAA AATGAAGTCTGACTAGAATTCTATTGCAGAGGCCAGTACATTTAGTATGGCATTGAGTTGTGATATAGTTTTACTTTGATGTGCATTTTG AATTTCAGCTACACCTAGATAGACGTAAAATGATAATTAAAATGCTGTAACCAACTTATCTAATAAAATTGGCAACCAGCCACTATTTTG TTGACTATGAGAAAGTTAAAAGTTTATGTTAATTTTTAGGGTCTGATAGAATATTTCATGTGTATTACAGTGGTATTCATATGCTATGTC >19903_19903_1_CSPG4-SON_CSPG4_chr15_75977076_ENST00000308508_SON_chr21_34945612_ENST00000290239_length(amino acids)=1614AA_BP=1483 MQSGPRPPLPAPGLALALTLTMLARLASAASFFGENHLEVPVATALTDIDLQLQFSTSQPEALLLLAAGPADHLLLQLYSGRLQVRLVLG QEELRLQTPAETLLSDSIPHTVVLTVVEGWATLSVDGFLNASSAVPGAPLEVPYGLFVGGTGTLGLPYLRGTSRPLRGCLHAATLNGRSL LRPLTPDVHEGCAEEFSASDDVALGFSGPHSLAAFPAWGTQDEGTLEFTLTTQSRQAPLAFQAGGRRGDFIYVDIFEGHLRAVVEKGQGT VLLHNSVPVADGQPHEVSVHINAHRLEISVDQYPTHTSNRGVLSYLEPRGSLLLGGLDAEASRHLQEHRLGLTPEATNASLLGCMEDLSV NGQRRGLREALLTRNMAAGCRLEEEEYEDDAYGHYEAFSTLAPEAWPAMELPEPCVPEPGLPPVFANFTQLLTISPLVVAEGGTAWLEWR HVQPTLDLMEAELRKSQVLFSVTRGARHGELELDIPGAQARKMFTLLDVVNRKARFIHDGSEDTSDQLVLEVSVTARVPMPSCLRRGQTY LLPIQVNPVNDPPHIIFPHGSLMVILEHTQKPLGPEVFQAYDPDSACEGLTFQVLGTSSGLPVERRDQPGEPATEFSCRELEAGSLVYVH RGGPAQDLTFRVSDGLQASPPATLKVVAIRPAIQIHRSTGLRLAQGSAMPILPANLSVETNAVGQDVSVLFRVTGALQFGELQKQGAGGV EGAEWWATQAFHQRDVEQGRVRYLSTDPQHHAYDTVENLALEVQVGQEILSNLSFPVTIQRATVWMLRLEPLHTQNTQQETLTTAHLEAT LEEAGPSPPTFHYEVVQAPRKGNLQLQGTRLSDGQGFTQDDIQAGRVTYGATARASEAVEDTFRFRVTAPPYFSPLYTFPIHIGGDPDAP VLTNVLLVVPEGGEGVLSADHLFVKSLNSASYLYEVMERPRHGRLAWRGTQDKTTMVTSFTNEDLLRGRLVYQHDDSETTEDDIPFVATR QGESSGDMAWEEVRGVFRVAIQPVNDHAPVQTISRIFHVARGGRRLLTTDDVAFSDADSGFADAQLVLTRKDLLFGSIVAVDEPTRPIYR FTQEDLRKRRVLFVHSGADRGWIQLQVSDGQHQATALLEVQASEPYLRVANGSSLVVPQGGQGTIDTAVLHLDTNLDIRSGDEVHYHVTA GPRWGQLVRAGQPATAFSQQDLLDGAVLYSHNGSLSPRDTMAFSVEAGPVHTDATLQVTIALEGPLAPLKLVRHKKIYVFQGEAAEIRRD QLEAAQEAVPPADIVFSVKSPPSAGYLVMVSRGALADEPPSLDPVQSFSQEAVDTGRVLYLHSRPEAWSDAFSLDVASGLGAPLEGVLVE LEVLPAAIPLEAQNFSVPEGGSLTLAPPLLRVSGPYFPTLLGLSLQVLEPPQHGALQKEDGPQARTLSAFSWRMVEEQLIRYVHDGSETL TDSFVLMANASEMDRQSHPVAFTVTVLPVNDQPPILTTNTGLQDQFLRAAPVTGGMGAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTD -------------------------------------------------------------- >19903_19903_2_CSPG4-SON_CSPG4_chr15_75977076_ENST00000308508_SON_chr21_34945612_ENST00000356577_length(transcript)=5995nt_BP=4542nt GCGCCCAGGAGCAGAGCCGCGCTCGCTCCACTCAGCTCCCAGCTCCCAGGACTCCGCTGGCTCCTCGCAAGTCCTGCCGCCCAGCCCGCC GGGATGCAGTCCGGGCCGCGGCCCCCACTTCCAGCCCCCGGCCTGGCCTTGGCTTTGACCCTGACTATGTTGGCCAGACTTGCATCCGCG GCTTCCTTCTTCGGTGAGAACCACCTGGAGGTGCCTGTGGCCACGGCTCTGACCGACATAGACCTGCAGCTGCAGTTCTCCACGTCCCAG CCCGAAGCCCTCCTTCTCCTGGCAGCAGGCCCAGCTGACCACCTCCTGCTGCAGCTCTACTCTGGACGCCTGCAGGTCAGACTTGTTCTG GGCCAGGAGGAGCTGAGGCTGCAGACTCCAGCAGAGACGCTGCTGAGTGACTCCATCCCCCACACTGTGGTGCTGACTGTCGTAGAGGGC TGGGCCACGTTGTCAGTCGATGGGTTTCTGAACGCCTCCTCAGCAGTCCCAGGAGCCCCCCTAGAGGTCCCCTATGGGCTCTTTGTTGGG GGCACTGGGACCCTTGGCCTGCCCTACCTGAGGGGAACCAGCCGACCCCTGAGGGGTTGCCTCCATGCAGCCACCCTCAATGGCCGCAGC CTCCTCCGGCCTCTGACCCCCGATGTGCATGAGGGCTGTGCTGAAGAGTTTTCTGCCAGTGATGATGTGGCCCTGGGCTTCTCTGGGCCC CACTCTCTGGCTGCCTTCCCTGCCTGGGGCACTCAGGACGAAGGAACCCTAGAGTTTACACTCACCACACAGAGCCGGCAGGCACCCTTG GCCTTCCAGGCAGGGGGCCGGCGTGGGGACTTCATCTATGTGGACATATTTGAGGGCCACCTGCGGGCCGTGGTGGAGAAGGGCCAGGGT ACCGTATTGCTCCACAACAGTGTGCCTGTGGCCGATGGGCAGCCCCATGAGGTCAGTGTCCACATCAATGCTCACCGGCTGGAAATCTCC GTGGACCAGTACCCTACGCATACTTCGAACCGAGGAGTCCTCAGCTACCTGGAGCCACGGGGCAGTCTCCTTCTCGGGGGGCTGGATGCA GAGGCCTCTCGTCACCTCCAGGAACACCGCCTGGGCCTGACACCAGAGGCCACCAATGCCTCCCTGCTGGGCTGCATGGAAGACCTCAGT GTCAATGGCCAGAGGCGGGGGCTGCGGGAAGCTTTGCTGACGCGCAACATGGCAGCCGGCTGCAGGCTGGAGGAGGAGGAGTATGAGGAC GATGCCTATGGACATTATGAAGCTTTCTCCACCCTGGCCCCTGAGGCTTGGCCAGCCATGGAGCTGCCTGAGCCATGCGTGCCTGAGCCA GGGCTGCCTCCTGTCTTTGCCAATTTCACCCAGCTGCTGACTATCAGCCCACTGGTGGTGGCCGAGGGGGGCACAGCCTGGCTTGAGTGG AGGCATGTGCAGCCCACGCTGGACCTGATGGAGGCTGAGCTGCGCAAATCCCAGGTGCTGTTCAGCGTGACCCGAGGGGCACGCCATGGC GAGCTCGAGCTGGACATCCCGGGAGCCCAGGCACGAAAAATGTTCACCCTCCTGGACGTGGTGAACCGCAAGGCCCGCTTCATCCACGAT GGCTCTGAGGACACCTCCGACCAGCTGGTGCTGGAGGTGTCGGTGACGGCTCGGGTGCCCATGCCCTCATGCCTTCGGAGGGGCCAAACA TACCTCCTGCCCATCCAGGTCAACCCTGTCAATGACCCACCCCACATCATCTTCCCACATGGCAGCCTCATGGTGATCCTGGAACACACG CAGAAGCCGCTGGGGCCTGAGGTTTTCCAGGCCTATGACCCGGACTCTGCCTGTGAGGGCCTCACCTTCCAGGTCCTTGGCACCTCCTCT GGCCTCCCCGTGGAGCGCCGAGACCAGCCTGGGGAGCCGGCGACCGAGTTCTCCTGCCGGGAGTTGGAGGCCGGCAGCCTAGTCTATGTC CACCGCGGTGGTCCTGCACAGGACTTGACGTTCCGGGTCAGCGATGGACTGCAGGCCAGCCCCCCGGCCACGCTGAAGGTGGTGGCCATC CGGCCGGCCATACAGATCCACCGCAGCACAGGGTTGCGACTGGCCCAAGGCTCTGCCATGCCCATCTTGCCCGCCAACCTGTCGGTGGAG ACCAATGCCGTGGGGCAGGATGTGAGCGTGCTGTTCCGCGTCACTGGGGCCCTGCAGTTTGGGGAGCTGCAGAAGCAGGGGGCAGGTGGG GTGGAGGGTGCTGAGTGGTGGGCCACACAGGCGTTCCACCAGCGGGATGTGGAGCAGGGCCGCGTGAGGTACCTGAGCACTGACCCACAG CACCACGCTTACGACACCGTGGAGAACCTGGCCCTGGAGGTGCAGGTGGGCCAGGAGATCCTGAGCAATCTGTCCTTCCCAGTGACCATC CAGAGAGCCACTGTGTGGATGCTGCGGCTGGAGCCACTGCACACTCAGAACACCCAGCAGGAGACCCTCACCACAGCCCACCTGGAGGCC ACCCTGGAGGAGGCAGGCCCAAGCCCCCCAACCTTCCATTATGAGGTGGTTCAGGCTCCCAGGAAAGGCAACCTTCAACTACAGGGCACA AGGCTGTCAGATGGCCAGGGCTTCACCCAGGATGACATACAGGCTGGCCGGGTGACCTATGGGGCCACAGCACGTGCCTCAGAGGCAGTC GAGGACACCTTCCGTTTCCGTGTCACAGCTCCACCATATTTCTCCCCACTCTATACCTTCCCCATCCACATTGGTGGTGACCCAGATGCG CCTGTCCTCACCAATGTCCTCCTCGTGGTGCCTGAGGGTGGTGAGGGTGTCCTCTCTGCTGACCACCTCTTTGTCAAGAGTCTCAACAGT GCCAGCTACCTCTATGAGGTCATGGAGCGGCCCCGCCATGGGAGGTTGGCTTGGCGTGGGACACAGGACAAGACCACTATGGTGACATCC TTCACCAATGAAGACCTGTTGCGTGGCCGGCTGGTCTACCAGCATGATGACTCCGAGACCACAGAAGATGATATCCCATTTGTTGCTACC CGCCAGGGCGAGAGCAGTGGTGACATGGCCTGGGAGGAGGTACGGGGTGTCTTCCGAGTGGCCATCCAGCCCGTGAATGACCACGCCCCT GTGCAGACCATCAGCCGGATCTTCCATGTGGCCCGGGGTGGGCGGCGGCTGCTGACTACAGACGACGTGGCCTTCAGCGATGCTGACTCG GGCTTTGCTGACGCCCAGCTGGTGCTTACCCGCAAGGACCTCCTCTTTGGCAGTATCGTGGCCGTAGATGAGCCCACGCGGCCCATCTAC CGCTTCACCCAGGAGGACCTCAGGAAGAGGCGAGTACTGTTCGTGCACTCAGGGGCTGACCGTGGCTGGATCCAGCTGCAGGTGTCCGAC GGGCAACACCAGGCCACTGCGCTGCTGGAGGTGCAGGCCTCGGAACCCTACCTCCGTGTGGCCAACGGCTCCAGCCTTGTGGTCCCTCAA GGAGGCCAGGGCACCATCGACACGGCCGTGCTCCACCTGGACACCAACCTCGACATCCGCAGTGGGGATGAGGTCCACTACCACGTCACA GCTGGCCCTCGCTGGGGACAGCTAGTCCGGGCTGGTCAGCCAGCCACAGCCTTCTCCCAGCAGGACCTGCTGGATGGGGCCGTTCTCTAT AGCCACAATGGCAGCCTCAGCCCCCGCGACACCATGGCCTTCTCCGTGGAAGCAGGGCCAGTGCACACGGATGCCACCCTACAAGTGACC ATTGCCCTAGAGGGCCCACTGGCCCCACTGAAGCTGGTCCGGCACAAGAAGATCTACGTCTTCCAGGGAGAGGCAGCTGAGATCAGAAGG GACCAGCTGGAGGCAGCCCAGGAGGCAGTGCCACCTGCAGACATCGTATTCTCAGTGAAGAGCCCACCGAGTGCCGGCTACCTGGTGATG GTGTCGCGTGGCGCCTTGGCAGATGAGCCACCCAGCCTGGACCCTGTGCAGAGCTTCTCCCAGGAGGCAGTGGACACAGGCAGGGTCCTG TACCTGCACTCCCGCCCTGAGGCCTGGAGCGATGCCTTCTCGCTGGATGTGGCCTCAGGCCTGGGTGCTCCCCTCGAGGGCGTCCTTGTG GAGCTGGAGGTGCTGCCCGCTGCCATCCCACTAGAGGCGCAAAACTTCAGCGTCCCTGAGGGTGGCAGCCTCACCCTGGCCCCTCCACTG CTCCGTGTCTCCGGGCCCTACTTCCCCACTCTCCTGGGCCTCAGCCTGCAGGTGCTGGAGCCACCCCAGCATGGAGCCCTGCAGAAGGAG GACGGACCTCAAGCCAGGACCCTCAGCGCCTTCTCCTGGAGAATGGTGGAAGAGCAGCTGATCCGCTACGTGCATGACGGGAGCGAGACA CTGACAGACAGTTTTGTCCTGATGGCTAATGCCTCCGAGATGGATCGCCAGAGCCATCCTGTGGCCTTCACTGTCACTGTCCTGCCTGTC AATGACCAACCCCCCATCCTCACTACAAACACAGGCCTGCAGGATCAGTTCTTAAGAGCAGCCCCGGTAACTGGAGGAATGGGAGCCGTT TTGATGAGAAAAATGGGCTGGAGAGAAGGAGAAGGATTAGGAAAAAACAAAGAAGGCAATAAGGAACCCATCCTAGTTGATTTTAAGACA GACCGAAAAGGTCTTGTTGCAGTAGGAGAAAGAGCACAAAAGAGGTCTGGGAACTTCTCTGCTGCAATGAAAGATCTGTCAGGCAAACAT CCTGTGTCTGCTTTGATGGAGATCTGTAATAAAAGAAGGTGGCAACCACCTGAATTTCTATTGGTCCATGATAGTGGCCCTGATCATCGC AAACATTTTCTCTTTAGGGTATTGAGAAATGGAGCCCTTACCAGACCCAATTGTATGTTTTTCTTGAATAGGTATTGATAAATGGAAGCG CTTACCAGCCCAGCTTTGCCAGCCCTAATAAGAAGCATGCTAAAGCCACAGCAGCTACTGTGGTTCTTCAAGCAATGGGCCTTGTACCAA AGGACCTCATGGCTAATGCCACTTGCTTCAGGAGTGCCTCACGTAGATAGATTGAGGTTTTATAATAATCATTTCAGAATTTTACTCTGC ATCACAATGTATTTCCTCTTTAATGTTGTAAATATTTGGCAATTTAAGACATTGTGTAAAAAGCAATCTGTAAAAACATCTCCAGGCTTT GATTTTTGTACCATGGAAATTGTATTTAACCATACAGGGTTTTGGTATGTTTATATTGTTTACCTTAGTGATGTATTTGTTTAAGTGGCT AACATCCAAACGACTGTTTGAAGGCATCAGAGTAATCTTCAGTGTGGAATGTTAAATAACGCTTTTATACTGTATTTTGTACTATGATGT AACTCCCCTTCCTTATGGCTAGGCTACTGTAACACTTGCCTGTAATCAGTGAAGGGCTGTGCACCTTGTACTATTTCACAATGGGTTCTG CTGGACAGATAATGGGCCAGTGTTATTGAGGTGATCAAGATCTGTTCCACAGGGCTAATGCCACCATCTCCCCTCAAAATTTTGTAGAGG TTCTAAAAAGAAAGTGGTATGTTGTGTGATGATCAGCACTAAGTCCTGCATTCCTGTTAAAGCCACTTGGGTCATAAGAAGGGAGTAAAA AATGAAGTCTGACTAGAATTCTATTGCAGAGGCCAGTACATTTAGTATGGCATTGAGTTGTGATATAGTTTTACTTTGATGTGCATTTTG AATTTCAGCTACACCTAGATAGACGTAAAATGATAATTAAAATGCTGTAACCAACTTATCTAATAAAATTGGCAACCAGCCACTATTTTG TTGACTATGAGAAAGTTAAAAGTTTATGTTAATTTTTAGGGTCTGATAGAATATTTCATGTGTATTACAGTGGTATTCATATGCTATGTC >19903_19903_2_CSPG4-SON_CSPG4_chr15_75977076_ENST00000308508_SON_chr21_34945612_ENST00000356577_length(amino acids)=1614AA_BP=1483 MQSGPRPPLPAPGLALALTLTMLARLASAASFFGENHLEVPVATALTDIDLQLQFSTSQPEALLLLAAGPADHLLLQLYSGRLQVRLVLG QEELRLQTPAETLLSDSIPHTVVLTVVEGWATLSVDGFLNASSAVPGAPLEVPYGLFVGGTGTLGLPYLRGTSRPLRGCLHAATLNGRSL LRPLTPDVHEGCAEEFSASDDVALGFSGPHSLAAFPAWGTQDEGTLEFTLTTQSRQAPLAFQAGGRRGDFIYVDIFEGHLRAVVEKGQGT VLLHNSVPVADGQPHEVSVHINAHRLEISVDQYPTHTSNRGVLSYLEPRGSLLLGGLDAEASRHLQEHRLGLTPEATNASLLGCMEDLSV NGQRRGLREALLTRNMAAGCRLEEEEYEDDAYGHYEAFSTLAPEAWPAMELPEPCVPEPGLPPVFANFTQLLTISPLVVAEGGTAWLEWR HVQPTLDLMEAELRKSQVLFSVTRGARHGELELDIPGAQARKMFTLLDVVNRKARFIHDGSEDTSDQLVLEVSVTARVPMPSCLRRGQTY LLPIQVNPVNDPPHIIFPHGSLMVILEHTQKPLGPEVFQAYDPDSACEGLTFQVLGTSSGLPVERRDQPGEPATEFSCRELEAGSLVYVH RGGPAQDLTFRVSDGLQASPPATLKVVAIRPAIQIHRSTGLRLAQGSAMPILPANLSVETNAVGQDVSVLFRVTGALQFGELQKQGAGGV EGAEWWATQAFHQRDVEQGRVRYLSTDPQHHAYDTVENLALEVQVGQEILSNLSFPVTIQRATVWMLRLEPLHTQNTQQETLTTAHLEAT LEEAGPSPPTFHYEVVQAPRKGNLQLQGTRLSDGQGFTQDDIQAGRVTYGATARASEAVEDTFRFRVTAPPYFSPLYTFPIHIGGDPDAP VLTNVLLVVPEGGEGVLSADHLFVKSLNSASYLYEVMERPRHGRLAWRGTQDKTTMVTSFTNEDLLRGRLVYQHDDSETTEDDIPFVATR QGESSGDMAWEEVRGVFRVAIQPVNDHAPVQTISRIFHVARGGRRLLTTDDVAFSDADSGFADAQLVLTRKDLLFGSIVAVDEPTRPIYR FTQEDLRKRRVLFVHSGADRGWIQLQVSDGQHQATALLEVQASEPYLRVANGSSLVVPQGGQGTIDTAVLHLDTNLDIRSGDEVHYHVTA GPRWGQLVRAGQPATAFSQQDLLDGAVLYSHNGSLSPRDTMAFSVEAGPVHTDATLQVTIALEGPLAPLKLVRHKKIYVFQGEAAEIRRD QLEAAQEAVPPADIVFSVKSPPSAGYLVMVSRGALADEPPSLDPVQSFSQEAVDTGRVLYLHSRPEAWSDAFSLDVASGLGAPLEGVLVE LEVLPAAIPLEAQNFSVPEGGSLTLAPPLLRVSGPYFPTLLGLSLQVLEPPQHGALQKEDGPQARTLSAFSWRMVEEQLIRYVHDGSETL TDSFVLMANASEMDRQSHPVAFTVTVLPVNDQPPILTTNTGLQDQFLRAAPVTGGMGAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTD -------------------------------------------------------------- >19903_19903_3_CSPG4-SON_CSPG4_chr15_75977076_ENST00000308508_SON_chr21_34945612_ENST00000381692_length(transcript)=5995nt_BP=4542nt GCGCCCAGGAGCAGAGCCGCGCTCGCTCCACTCAGCTCCCAGCTCCCAGGACTCCGCTGGCTCCTCGCAAGTCCTGCCGCCCAGCCCGCC GGGATGCAGTCCGGGCCGCGGCCCCCACTTCCAGCCCCCGGCCTGGCCTTGGCTTTGACCCTGACTATGTTGGCCAGACTTGCATCCGCG GCTTCCTTCTTCGGTGAGAACCACCTGGAGGTGCCTGTGGCCACGGCTCTGACCGACATAGACCTGCAGCTGCAGTTCTCCACGTCCCAG CCCGAAGCCCTCCTTCTCCTGGCAGCAGGCCCAGCTGACCACCTCCTGCTGCAGCTCTACTCTGGACGCCTGCAGGTCAGACTTGTTCTG GGCCAGGAGGAGCTGAGGCTGCAGACTCCAGCAGAGACGCTGCTGAGTGACTCCATCCCCCACACTGTGGTGCTGACTGTCGTAGAGGGC TGGGCCACGTTGTCAGTCGATGGGTTTCTGAACGCCTCCTCAGCAGTCCCAGGAGCCCCCCTAGAGGTCCCCTATGGGCTCTTTGTTGGG GGCACTGGGACCCTTGGCCTGCCCTACCTGAGGGGAACCAGCCGACCCCTGAGGGGTTGCCTCCATGCAGCCACCCTCAATGGCCGCAGC CTCCTCCGGCCTCTGACCCCCGATGTGCATGAGGGCTGTGCTGAAGAGTTTTCTGCCAGTGATGATGTGGCCCTGGGCTTCTCTGGGCCC CACTCTCTGGCTGCCTTCCCTGCCTGGGGCACTCAGGACGAAGGAACCCTAGAGTTTACACTCACCACACAGAGCCGGCAGGCACCCTTG GCCTTCCAGGCAGGGGGCCGGCGTGGGGACTTCATCTATGTGGACATATTTGAGGGCCACCTGCGGGCCGTGGTGGAGAAGGGCCAGGGT ACCGTATTGCTCCACAACAGTGTGCCTGTGGCCGATGGGCAGCCCCATGAGGTCAGTGTCCACATCAATGCTCACCGGCTGGAAATCTCC GTGGACCAGTACCCTACGCATACTTCGAACCGAGGAGTCCTCAGCTACCTGGAGCCACGGGGCAGTCTCCTTCTCGGGGGGCTGGATGCA GAGGCCTCTCGTCACCTCCAGGAACACCGCCTGGGCCTGACACCAGAGGCCACCAATGCCTCCCTGCTGGGCTGCATGGAAGACCTCAGT GTCAATGGCCAGAGGCGGGGGCTGCGGGAAGCTTTGCTGACGCGCAACATGGCAGCCGGCTGCAGGCTGGAGGAGGAGGAGTATGAGGAC GATGCCTATGGACATTATGAAGCTTTCTCCACCCTGGCCCCTGAGGCTTGGCCAGCCATGGAGCTGCCTGAGCCATGCGTGCCTGAGCCA GGGCTGCCTCCTGTCTTTGCCAATTTCACCCAGCTGCTGACTATCAGCCCACTGGTGGTGGCCGAGGGGGGCACAGCCTGGCTTGAGTGG AGGCATGTGCAGCCCACGCTGGACCTGATGGAGGCTGAGCTGCGCAAATCCCAGGTGCTGTTCAGCGTGACCCGAGGGGCACGCCATGGC GAGCTCGAGCTGGACATCCCGGGAGCCCAGGCACGAAAAATGTTCACCCTCCTGGACGTGGTGAACCGCAAGGCCCGCTTCATCCACGAT GGCTCTGAGGACACCTCCGACCAGCTGGTGCTGGAGGTGTCGGTGACGGCTCGGGTGCCCATGCCCTCATGCCTTCGGAGGGGCCAAACA TACCTCCTGCCCATCCAGGTCAACCCTGTCAATGACCCACCCCACATCATCTTCCCACATGGCAGCCTCATGGTGATCCTGGAACACACG CAGAAGCCGCTGGGGCCTGAGGTTTTCCAGGCCTATGACCCGGACTCTGCCTGTGAGGGCCTCACCTTCCAGGTCCTTGGCACCTCCTCT GGCCTCCCCGTGGAGCGCCGAGACCAGCCTGGGGAGCCGGCGACCGAGTTCTCCTGCCGGGAGTTGGAGGCCGGCAGCCTAGTCTATGTC CACCGCGGTGGTCCTGCACAGGACTTGACGTTCCGGGTCAGCGATGGACTGCAGGCCAGCCCCCCGGCCACGCTGAAGGTGGTGGCCATC CGGCCGGCCATACAGATCCACCGCAGCACAGGGTTGCGACTGGCCCAAGGCTCTGCCATGCCCATCTTGCCCGCCAACCTGTCGGTGGAG ACCAATGCCGTGGGGCAGGATGTGAGCGTGCTGTTCCGCGTCACTGGGGCCCTGCAGTTTGGGGAGCTGCAGAAGCAGGGGGCAGGTGGG GTGGAGGGTGCTGAGTGGTGGGCCACACAGGCGTTCCACCAGCGGGATGTGGAGCAGGGCCGCGTGAGGTACCTGAGCACTGACCCACAG CACCACGCTTACGACACCGTGGAGAACCTGGCCCTGGAGGTGCAGGTGGGCCAGGAGATCCTGAGCAATCTGTCCTTCCCAGTGACCATC CAGAGAGCCACTGTGTGGATGCTGCGGCTGGAGCCACTGCACACTCAGAACACCCAGCAGGAGACCCTCACCACAGCCCACCTGGAGGCC ACCCTGGAGGAGGCAGGCCCAAGCCCCCCAACCTTCCATTATGAGGTGGTTCAGGCTCCCAGGAAAGGCAACCTTCAACTACAGGGCACA AGGCTGTCAGATGGCCAGGGCTTCACCCAGGATGACATACAGGCTGGCCGGGTGACCTATGGGGCCACAGCACGTGCCTCAGAGGCAGTC GAGGACACCTTCCGTTTCCGTGTCACAGCTCCACCATATTTCTCCCCACTCTATACCTTCCCCATCCACATTGGTGGTGACCCAGATGCG CCTGTCCTCACCAATGTCCTCCTCGTGGTGCCTGAGGGTGGTGAGGGTGTCCTCTCTGCTGACCACCTCTTTGTCAAGAGTCTCAACAGT GCCAGCTACCTCTATGAGGTCATGGAGCGGCCCCGCCATGGGAGGTTGGCTTGGCGTGGGACACAGGACAAGACCACTATGGTGACATCC TTCACCAATGAAGACCTGTTGCGTGGCCGGCTGGTCTACCAGCATGATGACTCCGAGACCACAGAAGATGATATCCCATTTGTTGCTACC CGCCAGGGCGAGAGCAGTGGTGACATGGCCTGGGAGGAGGTACGGGGTGTCTTCCGAGTGGCCATCCAGCCCGTGAATGACCACGCCCCT GTGCAGACCATCAGCCGGATCTTCCATGTGGCCCGGGGTGGGCGGCGGCTGCTGACTACAGACGACGTGGCCTTCAGCGATGCTGACTCG GGCTTTGCTGACGCCCAGCTGGTGCTTACCCGCAAGGACCTCCTCTTTGGCAGTATCGTGGCCGTAGATGAGCCCACGCGGCCCATCTAC CGCTTCACCCAGGAGGACCTCAGGAAGAGGCGAGTACTGTTCGTGCACTCAGGGGCTGACCGTGGCTGGATCCAGCTGCAGGTGTCCGAC GGGCAACACCAGGCCACTGCGCTGCTGGAGGTGCAGGCCTCGGAACCCTACCTCCGTGTGGCCAACGGCTCCAGCCTTGTGGTCCCTCAA GGAGGCCAGGGCACCATCGACACGGCCGTGCTCCACCTGGACACCAACCTCGACATCCGCAGTGGGGATGAGGTCCACTACCACGTCACA GCTGGCCCTCGCTGGGGACAGCTAGTCCGGGCTGGTCAGCCAGCCACAGCCTTCTCCCAGCAGGACCTGCTGGATGGGGCCGTTCTCTAT AGCCACAATGGCAGCCTCAGCCCCCGCGACACCATGGCCTTCTCCGTGGAAGCAGGGCCAGTGCACACGGATGCCACCCTACAAGTGACC ATTGCCCTAGAGGGCCCACTGGCCCCACTGAAGCTGGTCCGGCACAAGAAGATCTACGTCTTCCAGGGAGAGGCAGCTGAGATCAGAAGG GACCAGCTGGAGGCAGCCCAGGAGGCAGTGCCACCTGCAGACATCGTATTCTCAGTGAAGAGCCCACCGAGTGCCGGCTACCTGGTGATG GTGTCGCGTGGCGCCTTGGCAGATGAGCCACCCAGCCTGGACCCTGTGCAGAGCTTCTCCCAGGAGGCAGTGGACACAGGCAGGGTCCTG TACCTGCACTCCCGCCCTGAGGCCTGGAGCGATGCCTTCTCGCTGGATGTGGCCTCAGGCCTGGGTGCTCCCCTCGAGGGCGTCCTTGTG GAGCTGGAGGTGCTGCCCGCTGCCATCCCACTAGAGGCGCAAAACTTCAGCGTCCCTGAGGGTGGCAGCCTCACCCTGGCCCCTCCACTG CTCCGTGTCTCCGGGCCCTACTTCCCCACTCTCCTGGGCCTCAGCCTGCAGGTGCTGGAGCCACCCCAGCATGGAGCCCTGCAGAAGGAG GACGGACCTCAAGCCAGGACCCTCAGCGCCTTCTCCTGGAGAATGGTGGAAGAGCAGCTGATCCGCTACGTGCATGACGGGAGCGAGACA CTGACAGACAGTTTTGTCCTGATGGCTAATGCCTCCGAGATGGATCGCCAGAGCCATCCTGTGGCCTTCACTGTCACTGTCCTGCCTGTC AATGACCAACCCCCCATCCTCACTACAAACACAGGCCTGCAGGATCAGTTCTTAAGAGCAGCCCCGGTAACTGGAGGAATGGGAGCCGTT TTGATGAGAAAAATGGGCTGGAGAGAAGGAGAAGGATTAGGAAAAAACAAAGAAGGCAATAAGGAACCCATCCTAGTTGATTTTAAGACA GACCGAAAAGGTCTTGTTGCAGTAGGAGAAAGAGCACAAAAGAGGTCTGGGAACTTCTCTGCTGCAATGAAAGATCTGTCAGGCAAACAT CCTGTGTCTGCTTTGATGGAGATCTGTAATAAAAGAAGGTGGCAACCACCTGAATTTCTATTGGTCCATGATAGTGGCCCTGATCATCGC AAACATTTTCTCTTTAGGGTATTGAGAAATGGAGCCCTTACCAGACCCAATTGTATGTTTTTCTTGAATAGGTATTGATAAATGGAAGCG CTTACCAGCCCAGCTTTGCCAGCCCTAATAAGAAGCATGCTAAAGCCACAGCAGCTACTGTGGTTCTTCAAGCAATGGGCCTTGTACCAA AGGACCTCATGGCTAATGCCACTTGCTTCAGGAGTGCCTCACGTAGATAGATTGAGGTTTTATAATAATCATTTCAGAATTTTACTCTGC ATCACAATGTATTTCCTCTTTAATGTTGTAAATATTTGGCAATTTAAGACATTGTGTAAAAAGCAATCTGTAAAAACATCTCCAGGCTTT GATTTTTGTACCATGGAAATTGTATTTAACCATACAGGGTTTTGGTATGTTTATATTGTTTACCTTAGTGATGTATTTGTTTAAGTGGCT AACATCCAAACGACTGTTTGAAGGCATCAGAGTAATCTTCAGTGTGGAATGTTAAATAACGCTTTTATACTGTATTTTGTACTATGATGT AACTCCCCTTCCTTATGGCTAGGCTACTGTAACACTTGCCTGTAATCAGTGAAGGGCTGTGCACCTTGTACTATTTCACAATGGGTTCTG CTGGACAGATAATGGGCCAGTGTTATTGAGGTGATCAAGATCTGTTCCACAGGGCTAATGCCACCATCTCCCCTCAAAATTTTGTAGAGG TTCTAAAAAGAAAGTGGTATGTTGTGTGATGATCAGCACTAAGTCCTGCATTCCTGTTAAAGCCACTTGGGTCATAAGAAGGGAGTAAAA AATGAAGTCTGACTAGAATTCTATTGCAGAGGCCAGTACATTTAGTATGGCATTGAGTTGTGATATAGTTTTACTTTGATGTGCATTTTG AATTTCAGCTACACCTAGATAGACGTAAAATGATAATTAAAATGCTGTAACCAACTTATCTAATAAAATTGGCAACCAGCCACTATTTTG TTGACTATGAGAAAGTTAAAAGTTTATGTTAATTTTTAGGGTCTGATAGAATATTTCATGTGTATTACAGTGGTATTCATATGCTATGTC >19903_19903_3_CSPG4-SON_CSPG4_chr15_75977076_ENST00000308508_SON_chr21_34945612_ENST00000381692_length(amino acids)=1614AA_BP=1483 MQSGPRPPLPAPGLALALTLTMLARLASAASFFGENHLEVPVATALTDIDLQLQFSTSQPEALLLLAAGPADHLLLQLYSGRLQVRLVLG QEELRLQTPAETLLSDSIPHTVVLTVVEGWATLSVDGFLNASSAVPGAPLEVPYGLFVGGTGTLGLPYLRGTSRPLRGCLHAATLNGRSL LRPLTPDVHEGCAEEFSASDDVALGFSGPHSLAAFPAWGTQDEGTLEFTLTTQSRQAPLAFQAGGRRGDFIYVDIFEGHLRAVVEKGQGT VLLHNSVPVADGQPHEVSVHINAHRLEISVDQYPTHTSNRGVLSYLEPRGSLLLGGLDAEASRHLQEHRLGLTPEATNASLLGCMEDLSV NGQRRGLREALLTRNMAAGCRLEEEEYEDDAYGHYEAFSTLAPEAWPAMELPEPCVPEPGLPPVFANFTQLLTISPLVVAEGGTAWLEWR HVQPTLDLMEAELRKSQVLFSVTRGARHGELELDIPGAQARKMFTLLDVVNRKARFIHDGSEDTSDQLVLEVSVTARVPMPSCLRRGQTY LLPIQVNPVNDPPHIIFPHGSLMVILEHTQKPLGPEVFQAYDPDSACEGLTFQVLGTSSGLPVERRDQPGEPATEFSCRELEAGSLVYVH RGGPAQDLTFRVSDGLQASPPATLKVVAIRPAIQIHRSTGLRLAQGSAMPILPANLSVETNAVGQDVSVLFRVTGALQFGELQKQGAGGV EGAEWWATQAFHQRDVEQGRVRYLSTDPQHHAYDTVENLALEVQVGQEILSNLSFPVTIQRATVWMLRLEPLHTQNTQQETLTTAHLEAT LEEAGPSPPTFHYEVVQAPRKGNLQLQGTRLSDGQGFTQDDIQAGRVTYGATARASEAVEDTFRFRVTAPPYFSPLYTFPIHIGGDPDAP VLTNVLLVVPEGGEGVLSADHLFVKSLNSASYLYEVMERPRHGRLAWRGTQDKTTMVTSFTNEDLLRGRLVYQHDDSETTEDDIPFVATR QGESSGDMAWEEVRGVFRVAIQPVNDHAPVQTISRIFHVARGGRRLLTTDDVAFSDADSGFADAQLVLTRKDLLFGSIVAVDEPTRPIYR FTQEDLRKRRVLFVHSGADRGWIQLQVSDGQHQATALLEVQASEPYLRVANGSSLVVPQGGQGTIDTAVLHLDTNLDIRSGDEVHYHVTA GPRWGQLVRAGQPATAFSQQDLLDGAVLYSHNGSLSPRDTMAFSVEAGPVHTDATLQVTIALEGPLAPLKLVRHKKIYVFQGEAAEIRRD QLEAAQEAVPPADIVFSVKSPPSAGYLVMVSRGALADEPPSLDPVQSFSQEAVDTGRVLYLHSRPEAWSDAFSLDVASGLGAPLEGVLVE LEVLPAAIPLEAQNFSVPEGGSLTLAPPLLRVSGPYFPTLLGLSLQVLEPPQHGALQKEDGPQARTLSAFSWRMVEEQLIRYVHDGSETL TDSFVLMANASEMDRQSHPVAFTVTVLPVNDQPPILTTNTGLQDQFLRAAPVTGGMGAVLMRKMGWREGEGLGKNKEGNKEPILVDFKTD -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for CSPG4-SON |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 631_1446 | 1483.0 | 2323.0 | COL5A1 |
| Hgene | CSPG4 | chr15:75977076 | chr21:34945612 | ENST00000308508 | - | 5 | 10 | 574_1040 | 1483.0 | 2323.0 | COL6A2 |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for CSPG4-SON |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for CSPG4-SON |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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