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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:CSRP1-CSRP1 (FusionGDB2 ID:19938)

Fusion Gene Summary for CSRP1-CSRP1

Fusion gene summary

Fusion gene information	Fusion gene name: CSRP1-CSRP1
	Fusion gene ID: 19938
		Hgene	Tgene
	Gene symbol	CSRP1	CSRP1
	Gene ID	1465	1465
	Gene name	cysteine and glycine rich protein 1	cysteine and glycine rich protein 1
	Synonyms	CRP\|CRP1\|CSRP\|CYRP\|D1S181E\|HEL-141\|HEL-S-286	CRP\|CRP1\|CSRP\|CYRP\|D1S181E\|HEL-141\|HEL-S-286
	Cytomap	1q32.1	1q32.1
	Type of gene	protein-coding	protein-coding
	Description	cysteine and glycine-rich protein 1LIM-domain proteincysteine-rich protein 1epididymis luminal protein 141epididymis secretory protein Li 286epididymis secretory sperm binding protein	cysteine and glycine-rich protein 1LIM-domain proteincysteine-rich protein 1epididymis luminal protein 141epididymis secretory protein Li 286epididymis secretory sperm binding protein
	Modification date	20200313	20200313
	UniProtAcc	P21291	P21291
	Ensembl transtripts involved in fusion gene	ENST00000340006, ENST00000367306, ENST00000526723, ENST00000532460, ENST00000533432, ENST00000458271, ENST00000531916,	ENST00000458271, ENST00000340006, ENST00000367306, ENST00000526723, ENST00000531916, ENST00000532460, ENST00000533432,
Fusion gene scores	* DoF score	6 X 9 X 4=216	7 X 9 X 5=315
	# samples	9	11
	** MAII score	log2(9/216*10)=-1.26303440583379 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(11/315*10)=-1.51784830486262 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: CSRP1 [Title/Abstract] AND CSRP1 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	CSRP1(201452740)-CSRP1(201453416), # samples:1 CSRP1(201452680)-CSRP1(201452659), # samples:1 CSRP1(201453046)-CSRP1(201453184), # samples:1 CSRP1(201457986)-CSRP1(201458086), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across CSRP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across CSRP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChiTaRS5.0	N/A	AA568409	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
ChiTaRS5.0	N/A	AW900244	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
ChiTaRS5.0	N/A	BF870360	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
ChiTaRS5.0	N/A	BF882820	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+

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Fusion Gene ORF analysis for CSRP1-CSRP1

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000340006	ENST00000458271	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
5CDS-5UTR	ENST00000367306	ENST00000458271	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
5CDS-5UTR	ENST00000526723	ENST00000458271	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
5CDS-5UTR	ENST00000532460	ENST00000458271	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
5CDS-5UTR	ENST00000533432	ENST00000458271	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
5UTR-3CDS	ENST00000458271	ENST00000340006	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
5UTR-3CDS	ENST00000458271	ENST00000367306	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
5UTR-3CDS	ENST00000458271	ENST00000526723	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
5UTR-3CDS	ENST00000458271	ENST00000531916	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
5UTR-3CDS	ENST00000458271	ENST00000532460	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
5UTR-3CDS	ENST00000458271	ENST00000533432	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
5UTR-5UTR	ENST00000458271	ENST00000458271	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
Frame-shift	ENST00000367306	ENST00000340006	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
Frame-shift	ENST00000367306	ENST00000367306	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
Frame-shift	ENST00000367306	ENST00000526723	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
Frame-shift	ENST00000367306	ENST00000531916	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
Frame-shift	ENST00000367306	ENST00000532460	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
Frame-shift	ENST00000367306	ENST00000533432	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
Frame-shift	ENST00000532460	ENST00000340006	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
Frame-shift	ENST00000532460	ENST00000367306	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
Frame-shift	ENST00000532460	ENST00000526723	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
Frame-shift	ENST00000532460	ENST00000531916	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
Frame-shift	ENST00000532460	ENST00000532460	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
Frame-shift	ENST00000532460	ENST00000533432	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
Frame-shift	ENST00000533432	ENST00000340006	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
Frame-shift	ENST00000533432	ENST00000367306	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
Frame-shift	ENST00000533432	ENST00000526723	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
Frame-shift	ENST00000533432	ENST00000531916	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
Frame-shift	ENST00000533432	ENST00000532460	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
Frame-shift	ENST00000533432	ENST00000533432	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
In-frame	ENST00000340006	ENST00000340006	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
In-frame	ENST00000340006	ENST00000367306	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
In-frame	ENST00000340006	ENST00000526723	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
In-frame	ENST00000340006	ENST00000531916	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
In-frame	ENST00000340006	ENST00000532460	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
In-frame	ENST00000340006	ENST00000533432	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
In-frame	ENST00000526723	ENST00000340006	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
In-frame	ENST00000526723	ENST00000367306	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
In-frame	ENST00000526723	ENST00000526723	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
In-frame	ENST00000526723	ENST00000531916	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
In-frame	ENST00000526723	ENST00000532460	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
In-frame	ENST00000526723	ENST00000533432	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
intron-3CDS	ENST00000531916	ENST00000340006	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
intron-3CDS	ENST00000531916	ENST00000367306	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
intron-3CDS	ENST00000531916	ENST00000526723	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
intron-3CDS	ENST00000531916	ENST00000531916	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
intron-3CDS	ENST00000531916	ENST00000532460	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
intron-3CDS	ENST00000531916	ENST00000533432	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
intron-3UTR	ENST00000340006	ENST00000340006	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000340006	ENST00000340006	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000340006	ENST00000367306	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000340006	ENST00000367306	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000340006	ENST00000531916	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000340006	ENST00000532460	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000340006	ENST00000532460	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000367306	ENST00000340006	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000367306	ENST00000340006	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000367306	ENST00000367306	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000367306	ENST00000367306	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000367306	ENST00000531916	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000367306	ENST00000532460	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000367306	ENST00000532460	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000458271	ENST00000340006	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000458271	ENST00000340006	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000458271	ENST00000367306	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000458271	ENST00000367306	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000458271	ENST00000531916	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000458271	ENST00000532460	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000458271	ENST00000532460	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000526723	ENST00000340006	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000526723	ENST00000340006	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000526723	ENST00000367306	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000526723	ENST00000367306	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000526723	ENST00000531916	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000526723	ENST00000532460	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000526723	ENST00000532460	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000531916	ENST00000340006	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000531916	ENST00000340006	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000531916	ENST00000367306	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000531916	ENST00000367306	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000531916	ENST00000531916	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000531916	ENST00000532460	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000531916	ENST00000532460	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000532460	ENST00000340006	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000532460	ENST00000340006	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000532460	ENST00000367306	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000532460	ENST00000367306	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000532460	ENST00000531916	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000532460	ENST00000532460	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000532460	ENST00000532460	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000533432	ENST00000340006	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000533432	ENST00000340006	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000533432	ENST00000367306	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000533432	ENST00000367306	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000533432	ENST00000531916	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-3UTR	ENST00000533432	ENST00000532460	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-3UTR	ENST00000533432	ENST00000532460	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-5UTR	ENST00000531916	ENST00000458271	CSRP1	chr1	201457986	-	CSRP1	chr1	201458086	+
intron-intron	ENST00000340006	ENST00000340006	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000340006	ENST00000367306	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000340006	ENST00000458271	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000340006	ENST00000458271	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000340006	ENST00000458271	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000340006	ENST00000526723	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000340006	ENST00000526723	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000340006	ENST00000526723	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000340006	ENST00000531916	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000340006	ENST00000531916	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000340006	ENST00000532460	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000340006	ENST00000533432	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000340006	ENST00000533432	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000340006	ENST00000533432	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000367306	ENST00000340006	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000367306	ENST00000367306	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000367306	ENST00000458271	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000367306	ENST00000458271	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000367306	ENST00000458271	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000367306	ENST00000526723	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000367306	ENST00000526723	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000367306	ENST00000526723	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000367306	ENST00000531916	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000367306	ENST00000531916	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000367306	ENST00000532460	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000367306	ENST00000533432	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000367306	ENST00000533432	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000367306	ENST00000533432	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000458271	ENST00000340006	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000458271	ENST00000367306	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000458271	ENST00000458271	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000458271	ENST00000458271	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000458271	ENST00000458271	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000458271	ENST00000526723	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000458271	ENST00000526723	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000458271	ENST00000526723	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000458271	ENST00000531916	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000458271	ENST00000531916	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000458271	ENST00000532460	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000458271	ENST00000533432	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000458271	ENST00000533432	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000458271	ENST00000533432	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000526723	ENST00000340006	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000526723	ENST00000367306	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000526723	ENST00000458271	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000526723	ENST00000458271	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000526723	ENST00000458271	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000526723	ENST00000526723	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000526723	ENST00000526723	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000526723	ENST00000526723	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000526723	ENST00000531916	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000526723	ENST00000531916	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000526723	ENST00000532460	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000526723	ENST00000533432	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000526723	ENST00000533432	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000526723	ENST00000533432	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000531916	ENST00000340006	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000531916	ENST00000367306	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000531916	ENST00000458271	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000531916	ENST00000458271	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000531916	ENST00000458271	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000531916	ENST00000526723	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000531916	ENST00000526723	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000531916	ENST00000526723	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000531916	ENST00000531916	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000531916	ENST00000531916	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000531916	ENST00000532460	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000531916	ENST00000533432	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000531916	ENST00000533432	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000531916	ENST00000533432	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000532460	ENST00000340006	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000532460	ENST00000367306	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000532460	ENST00000458271	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000532460	ENST00000458271	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000532460	ENST00000458271	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000532460	ENST00000526723	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000532460	ENST00000526723	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000532460	ENST00000526723	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000532460	ENST00000531916	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000532460	ENST00000531916	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000532460	ENST00000532460	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000532460	ENST00000533432	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000532460	ENST00000533432	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000532460	ENST00000533432	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000533432	ENST00000340006	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000533432	ENST00000367306	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000533432	ENST00000458271	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000533432	ENST00000458271	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000533432	ENST00000458271	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000533432	ENST00000526723	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000533432	ENST00000526723	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000533432	ENST00000526723	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+
intron-intron	ENST00000533432	ENST00000531916	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000533432	ENST00000531916	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000533432	ENST00000532460	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000533432	ENST00000533432	CSRP1	chr1	201452680	-	CSRP1	chr1	201452659	+
intron-intron	ENST00000533432	ENST00000533432	CSRP1	chr1	201452740	-	CSRP1	chr1	201453416	-
intron-intron	ENST00000533432	ENST00000533432	CSRP1	chr1	201453046	-	CSRP1	chr1	201453184	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

No-coding score

Coding score

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Fusion Genomic Features for CSRP1-CSRP1

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CSRP1-CSRP1

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:201452740/chr1:201453416)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
CSRP1 P21291	CSRP1 P21291
FUNCTION: Could play a role in neuronal development.	FUNCTION: Could play a role in neuronal development.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000340006

63_78

137

194.0

Compositional bias

Note=Gly-rich

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000367306

63_78

137

194.0

Compositional bias

Note=Gly-rich

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000532460

63_78

137

194.0

Compositional bias

Note=Gly-rich

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000533432

63_78

137

194.0

Compositional bias

Note=Gly-rich

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000340006

10_61

137

194.0

Domain

LIM zinc-binding 1

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000367306

10_61

137

194.0

Domain

LIM zinc-binding 1

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000532460

10_61

137

194.0

Domain

LIM zinc-binding 1

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000533432

10_61

137

194.0

Domain

LIM zinc-binding 1

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000340006

64_69

137

194.0

Motif

Nuclear localization signal

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000367306

64_69

137

194.0

Motif

Nuclear localization signal

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000532460

64_69

137

194.0

Motif

Nuclear localization signal

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000533432

64_69

137

194.0

Motif

Nuclear localization signal

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000340006

176_187

194.0

Compositional bias

Note=Gly-rich

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000340006

63_78

194.0

Compositional bias

Note=Gly-rich

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000367306

176_187

194.0

Compositional bias

Note=Gly-rich

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000367306

63_78

194.0

Compositional bias

Note=Gly-rich

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000532460

176_187

194.0

Compositional bias

Note=Gly-rich

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000532460

63_78

194.0

Compositional bias

Note=Gly-rich

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000533432

176_187

194.0

Compositional bias

Note=Gly-rich

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000533432

63_78

194.0

Compositional bias

Note=Gly-rich

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000340006

10_61

194.0

Domain

LIM zinc-binding 1

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000340006

119_170

194.0

Domain

LIM zinc-binding 2

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000367306

10_61

194.0

Domain

LIM zinc-binding 1

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000367306

119_170

194.0

Domain

LIM zinc-binding 2

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000532460

10_61

194.0

Domain

LIM zinc-binding 1

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000532460

119_170

194.0

Domain

LIM zinc-binding 2

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000533432

10_61

194.0

Domain

LIM zinc-binding 1

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000533432

119_170

194.0

Domain

LIM zinc-binding 2

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000340006

64_69

194.0

Motif

Nuclear localization signal

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000367306

64_69

194.0

Motif

Nuclear localization signal

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000532460

64_69

194.0

Motif

Nuclear localization signal

Tgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000533432

64_69

194.0

Motif

Nuclear localization signal

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000340006

176_187

137

194.0

Compositional bias

Note=Gly-rich

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000367306

176_187

137

194.0

Compositional bias

Note=Gly-rich

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000532460

176_187

137

194.0

Compositional bias

Note=Gly-rich

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000533432

176_187

137

194.0

Compositional bias

Note=Gly-rich

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000340006

119_170

137

194.0

Domain

LIM zinc-binding 2

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000367306

119_170

137

194.0

Domain

LIM zinc-binding 2

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000532460

119_170

137

194.0

Domain

LIM zinc-binding 2

Hgene

CSRP1

chr1:201457986

chr1:201458086

ENST00000533432

119_170

137

194.0

Domain

LIM zinc-binding 2

Top

Fusion Gene Sequence for CSRP1-CSRP1

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

Top

Fusion Gene PPI Analysis for CSRP1-CSRP1

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for CSRP1-CSRP1

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for CSRP1-CSRP1

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source