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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CTDP1-NFATC1 (FusionGDB2 ID:20153)

Fusion Gene Summary for CTDP1-NFATC1

check button Fusion gene summary
Fusion gene informationFusion gene name: CTDP1-NFATC1
Fusion gene ID: 20153
HgeneTgene
Gene symbol

CTDP1

NFATC1

Gene ID

9150

4772

Gene nameCTD phosphatase subunit 1nuclear factor of activated T cells 1
SynonymsCCFDN|FCP1NF-ATC|NF-ATc1.2|NFAT2|NFATc
Cytomap

18q23

18q23

Type of geneprotein-codingprotein-coding
DescriptionRNA polymerase II subunit A C-terminal domain phosphataseCTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1CTD of POLR2A, phosphatase of, subunit 1TFIIF-associating CTD phosphatase 1serine phosphatase FCP1atranscrinuclear factor of activated T-cells, cytoplasmic 1NFAT transcription complex cytosolic componentnuclear factor of activated T-cells 'c'nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
Modification date2020031320200313
UniProtAcc

Q9Y5B0

O95644

Ensembl transtripts involved in fusion geneENST00000075430, ENST00000299543, 
ENST00000587623, 		ENST00000590172, 
ENST00000318065, ENST00000329101, 
ENST00000397790, ENST00000427363, 
ENST00000542384, ENST00000545796, 
ENST00000586434, ENST00000587635, 
ENST00000591814, ENST00000592223, 
ENST00000253506, 
Fusion gene scores* DoF score4 X 5 X 4=809 X 9 X 7=567
# samples 411
** MAII scorelog2(4/80*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/567*10)=-2.36584521141757
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CTDP1 [Title/Abstract] AND NFATC1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCTDP1(77475528)-NFATC1(77287528), # samples:2
Anticipated loss of major functional domain due to fusion event.CTDP1-NFATC1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CTDP1-NFATC1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
CTDP1-NFATC1 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCTDP1

GO:0006470

protein dephosphorylation

9765293|22692537

HgeneCTDP1

GO:0043923

positive regulation by host of viral transcription

15723517

TgeneNFATC1

GO:0033173

calcineurin-NFAT signaling cascade

14979875

TgeneNFATC1

GO:0035556

intracellular signal transduction

14749367

TgeneNFATC1

GO:0045893

positive regulation of transcription, DNA-templated

14749367|14979875

TgeneNFATC1

GO:0045944

positive regulation of transcription by RNA polymerase II

14979875

TgeneNFATC1

GO:1905064

negative regulation of vascular smooth muscle cell differentiation

23853098


check buttonFusion gene breakpoints across CTDP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NFATC1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LAMLTCGA-AB-2811-03BCTDP1chr18

77478016

-NFATC1chr18

77227450

+
ChimerDB4SARCTCGA-3B-A9HJ-01ACTDP1chr18

77475528

+NFATC1chr18

77287528

+
ChimerDB4SARCTCGA-X6-A7WA-01ACTDP1chr18

77475528

-NFATC1chr18

77287528

+


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Fusion Gene ORF analysis for CTDP1-NFATC1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000075430ENST00000590172CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-3UTRENST00000299543ENST00000590172CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000075430ENST00000318065CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000075430ENST00000329101CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000075430ENST00000397790CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000075430ENST00000427363CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000075430ENST00000542384CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000075430ENST00000545796CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000075430ENST00000586434CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000075430ENST00000587635CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000075430ENST00000590172CTDP1chr18

77478016

-NFATC1chr18

77227450

+
5CDS-intronENST00000075430ENST00000591814CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000075430ENST00000592223CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000299543ENST00000318065CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000299543ENST00000329101CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000299543ENST00000397790CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000299543ENST00000427363CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000299543ENST00000542384CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000299543ENST00000545796CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000299543ENST00000586434CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000299543ENST00000587635CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000299543ENST00000590172CTDP1chr18

77478016

-NFATC1chr18

77227450

+
5CDS-intronENST00000299543ENST00000591814CTDP1chr18

77475528

+NFATC1chr18

77287528

+
5CDS-intronENST00000299543ENST00000592223CTDP1chr18

77475528

+NFATC1chr18

77287528

+
Frame-shiftENST00000075430ENST00000253506CTDP1chr18

77478016

-NFATC1chr18

77227450

+
Frame-shiftENST00000075430ENST00000253506CTDP1chr18

77475528

+NFATC1chr18

77287528

+
Frame-shiftENST00000075430ENST00000318065CTDP1chr18

77478016

-NFATC1chr18

77227450

+
Frame-shiftENST00000075430ENST00000329101CTDP1chr18

77478016

-NFATC1chr18

77227450

+
Frame-shiftENST00000075430ENST00000397790CTDP1chr18

77478016

-NFATC1chr18

77227450

+
Frame-shiftENST00000075430ENST00000427363CTDP1chr18

77478016

-NFATC1chr18

77227450

+
Frame-shiftENST00000075430ENST00000542384CTDP1chr18

77478016

-NFATC1chr18

77227450

+
Frame-shiftENST00000075430ENST00000545796CTDP1chr18

77478016

-NFATC1chr18

77227450

+
Frame-shiftENST00000075430ENST00000586434CTDP1chr18

77478016

-NFATC1chr18

77227450

+
Frame-shiftENST00000075430ENST00000592223CTDP1chr18

77478016

-NFATC1chr18

77227450

+
Frame-shiftENST00000299543ENST00000253506CTDP1chr18

77478016

-NFATC1chr18

77227450

+
Frame-shiftENST00000299543ENST00000253506CTDP1chr18

77475528

+NFATC1chr18

77287528

+
Frame-shiftENST00000299543ENST00000318065CTDP1chr18

77478016

-NFATC1chr18

77227450

+
Frame-shiftENST00000299543ENST00000329101CTDP1chr18

77478016

-NFATC1chr18

77227450

+
Frame-shiftENST00000299543ENST00000397790CTDP1chr18

77478016

-NFATC1chr18

77227450

+
Frame-shiftENST00000299543ENST00000427363CTDP1chr18

77478016

-NFATC1chr18

77227450

+
Frame-shiftENST00000299543ENST00000542384CTDP1chr18

77478016

-NFATC1chr18

77227450

+
Frame-shiftENST00000299543ENST00000545796CTDP1chr18

77478016

-NFATC1chr18

77227450

+
Frame-shiftENST00000299543ENST00000586434CTDP1chr18

77478016

-NFATC1chr18

77227450

+
Frame-shiftENST00000299543ENST00000592223CTDP1chr18

77478016

-NFATC1chr18

77227450

+
In-frameENST00000075430ENST00000587635CTDP1chr18

77478016

-NFATC1chr18

77227450

+
In-frameENST00000075430ENST00000591814CTDP1chr18

77478016

-NFATC1chr18

77227450

+
In-frameENST00000299543ENST00000587635CTDP1chr18

77478016

-NFATC1chr18

77227450

+
In-frameENST00000299543ENST00000591814CTDP1chr18

77478016

-NFATC1chr18

77227450

+
intron-3CDSENST00000587623ENST00000253506CTDP1chr18

77478016

-NFATC1chr18

77227450

+
intron-3CDSENST00000587623ENST00000253506CTDP1chr18

77475528

+NFATC1chr18

77287528

+
intron-3CDSENST00000587623ENST00000318065CTDP1chr18

77478016

-NFATC1chr18

77227450

+
intron-3CDSENST00000587623ENST00000329101CTDP1chr18

77478016

-NFATC1chr18

77227450

+
intron-3CDSENST00000587623ENST00000397790CTDP1chr18

77478016

-NFATC1chr18

77227450

+
intron-3CDSENST00000587623ENST00000427363CTDP1chr18

77478016

-NFATC1chr18

77227450

+
intron-3CDSENST00000587623ENST00000542384CTDP1chr18

77478016

-NFATC1chr18

77227450

+
intron-3CDSENST00000587623ENST00000545796CTDP1chr18

77478016

-NFATC1chr18

77227450

+
intron-3CDSENST00000587623ENST00000586434CTDP1chr18

77478016

-NFATC1chr18

77227450

+
intron-3CDSENST00000587623ENST00000587635CTDP1chr18

77478016

-NFATC1chr18

77227450

+
intron-3CDSENST00000587623ENST00000591814CTDP1chr18

77478016

-NFATC1chr18

77227450

+
intron-3CDSENST00000587623ENST00000592223CTDP1chr18

77478016

-NFATC1chr18

77227450

+
intron-3UTRENST00000587623ENST00000590172CTDP1chr18

77475528

+NFATC1chr18

77287528

+
intron-intronENST00000587623ENST00000318065CTDP1chr18

77475528

+NFATC1chr18

77287528

+
intron-intronENST00000587623ENST00000329101CTDP1chr18

77475528

+NFATC1chr18

77287528

+
intron-intronENST00000587623ENST00000397790CTDP1chr18

77475528

+NFATC1chr18

77287528

+
intron-intronENST00000587623ENST00000427363CTDP1chr18

77475528

+NFATC1chr18

77287528

+
intron-intronENST00000587623ENST00000542384CTDP1chr18

77475528

+NFATC1chr18

77287528

+
intron-intronENST00000587623ENST00000545796CTDP1chr18

77475528

+NFATC1chr18

77287528

+
intron-intronENST00000587623ENST00000586434CTDP1chr18

77475528

+NFATC1chr18

77287528

+
intron-intronENST00000587623ENST00000587635CTDP1chr18

77475528

+NFATC1chr18

77287528

+
intron-intronENST00000587623ENST00000590172CTDP1chr18

77478016

-NFATC1chr18

77227450

+
intron-intronENST00000587623ENST00000591814CTDP1chr18

77475528

+NFATC1chr18

77287528

+
intron-intronENST00000587623ENST00000592223CTDP1chr18

77475528

+NFATC1chr18

77287528

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000299543CTDP1chr1877478016-ENST00000591814NFATC1chr1877227450+31172564692609846
ENST00000299543CTDP1chr1877478016-ENST00000587635NFATC1chr1877227450+27912564692609846
ENST00000075430CTDP1chr1877478016-ENST00000591814NFATC1chr1877227450+30722519242564846
ENST00000075430CTDP1chr1877478016-ENST00000587635NFATC1chr1877227450+27462519242564846

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000299543ENST00000591814CTDP1chr1877478016-NFATC1chr1877227450+0.005417840.9945821
ENST00000299543ENST00000587635CTDP1chr1877478016-NFATC1chr1877227450+0.0070221420.9929778
ENST00000075430ENST00000591814CTDP1chr1877478016-NFATC1chr1877227450+0.0055379920.99446195
ENST00000075430ENST00000587635CTDP1chr1877478016-NFATC1chr1877227450+0.0071940020.992806

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Fusion Genomic Features for CTDP1-NFATC1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CTDP1chr1877475528+NFATC1chr1877287527+0.0017566140.99824345
CTDP1chr1877475528+NFATC1chr1877287527+0.0017566140.99824345

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CTDP1-NFATC1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr18:77475528/chr18:77287528)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CTDP1

Q9Y5B0

NFATC1

O95644

FUNCTION: Processively dephosphorylates 'Ser-2' and 'Ser-5' of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit. This promotes the activity of RNA polymerase II. Plays a role in the exit from mitosis by dephosphorylating crucial mitotic substrates (USP44, CDC20 and WEE1) that are required for M-phase-promoting factor (MPF)/CDK1 inactivation. {ECO:0000269|PubMed:22692537}.FUNCTION: Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells (PubMed:10358178). Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function (By similarity). {ECO:0000250|UniProtKB:O88942, ECO:0000269|PubMed:10358178}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCTDP1chr18:77478016chr18:77227450ENST00000075430-1012455_478805868.0Compositional biasNote=Ser-rich
HgeneCTDP1chr18:77478016chr18:77227450ENST00000075430-1012577_582805868.0Compositional biasNote=Poly-Glu
HgeneCTDP1chr18:77478016chr18:77227450ENST00000299543-1013455_478805962.0Compositional biasNote=Ser-rich
HgeneCTDP1chr18:77478016chr18:77227450ENST00000299543-1013577_582805962.0Compositional biasNote=Poly-Glu
HgeneCTDP1chr18:77478016chr18:77227450ENST00000075430-1012178_344805868.0DomainFCP1 homology
HgeneCTDP1chr18:77478016chr18:77227450ENST00000075430-1012629_728805868.0DomainBRCT
HgeneCTDP1chr18:77478016chr18:77227450ENST00000299543-1013178_344805962.0DomainFCP1 homology
HgeneCTDP1chr18:77478016chr18:77227450ENST00000299543-1013629_728805962.0DomainBRCT
TgeneNFATC1chr18:77478016chr18:77227450ENST0000039779059439_446181354.0DNA binding.
TgeneNFATC1chr18:77478016chr18:77227450ENST0000039779059410_592181354.0DomainRHD
TgeneNFATC1chr18:77478016chr18:77227450ENST00000253506610682_684653826.0MotifNote=Nuclear localization signal
TgeneNFATC1chr18:77478016chr18:77227450ENST00000253506610924_933653826.0MotifNote=Nuclear export signal
TgeneNFATC1chr18:77478016chr18:77227450ENST00000318065610682_684640813.0MotifNote=Nuclear localization signal
TgeneNFATC1chr18:77478016chr18:77227450ENST00000318065610924_933640813.0MotifNote=Nuclear export signal
TgeneNFATC1chr18:77478016chr18:77227450ENST00000329101610682_684640931.0MotifNote=Nuclear localization signal
TgeneNFATC1chr18:77478016chr18:77227450ENST00000329101610924_933640931.0MotifNote=Nuclear export signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000039779059265_267181354.0MotifNote=Nuclear localization signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000039779059310_321181354.0MotifNote=Nuclear export signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000039779059682_684181354.0MotifNote=Nuclear localization signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000039779059924_933181354.0MotifNote=Nuclear export signal
TgeneNFATC1chr18:77478016chr18:77227450ENST00000427363610682_684653944.0MotifNote=Nuclear localization signal
TgeneNFATC1chr18:77478016chr18:77227450ENST00000427363610924_933653944.0MotifNote=Nuclear export signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000054238469682_684653714.0MotifNote=Nuclear localization signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000054238469924_933653714.0MotifNote=Nuclear export signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000058643469682_684640701.0MotifNote=Nuclear localization signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000058643469924_933640701.0MotifNote=Nuclear export signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059181468682_684653717.0MotifNote=Nuclear localization signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059181468924_933653717.0MotifNote=Nuclear export signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059222368682_684640704.0MotifNote=Nuclear localization signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059222368924_933640704.0MotifNote=Nuclear export signal
TgeneNFATC1chr18:77478016chr18:77227450ENST00000253506610703_943653826.0RegionNote=Trans-activation domain B (TAD-B)
TgeneNFATC1chr18:77478016chr18:77227450ENST00000318065610703_943640813.0RegionNote=Trans-activation domain B (TAD-B)
TgeneNFATC1chr18:77478016chr18:77227450ENST00000329101610703_943640931.0RegionNote=Trans-activation domain B (TAD-B)
TgeneNFATC1chr18:77478016chr18:77227450ENST0000039779059203_298181354.0RegionNote=3 X SP repeats
TgeneNFATC1chr18:77478016chr18:77227450ENST0000039779059703_943181354.0RegionNote=Trans-activation domain B (TAD-B)
TgeneNFATC1chr18:77478016chr18:77227450ENST00000427363610703_943653944.0RegionNote=Trans-activation domain B (TAD-B)
TgeneNFATC1chr18:77478016chr18:77227450ENST0000054238469703_943653714.0RegionNote=Trans-activation domain B (TAD-B)
TgeneNFATC1chr18:77478016chr18:77227450ENST0000058643469703_943640701.0RegionNote=Trans-activation domain B (TAD-B)
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059181468703_943653717.0RegionNote=Trans-activation domain B (TAD-B)
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059222368703_943640704.0RegionNote=Trans-activation domain B (TAD-B)
TgeneNFATC1chr18:77478016chr18:77227450ENST0000039779059203_219181354.0RepeatNote=1
TgeneNFATC1chr18:77478016chr18:77227450ENST0000039779059233_249181354.0RepeatNote=2
TgeneNFATC1chr18:77478016chr18:77227450ENST0000039779059282_298181354.0RepeatNote=3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneNFATC1chr18:77478016chr18:77227450ENST00000253506610439_446653826.0DNA binding.
TgeneNFATC1chr18:77478016chr18:77227450ENST00000318065610439_446640813.0DNA binding.
TgeneNFATC1chr18:77478016chr18:77227450ENST00000329101610439_446640931.0DNA binding.
TgeneNFATC1chr18:77478016chr18:77227450ENST00000427363610439_446653944.0DNA binding.
TgeneNFATC1chr18:77478016chr18:77227450ENST0000054238469439_446653714.0DNA binding.
TgeneNFATC1chr18:77478016chr18:77227450ENST0000058643469439_446640701.0DNA binding.
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059181468439_446653717.0DNA binding.
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059222368439_446640704.0DNA binding.
TgeneNFATC1chr18:77478016chr18:77227450ENST00000253506610410_592653826.0DomainRHD
TgeneNFATC1chr18:77478016chr18:77227450ENST00000318065610410_592640813.0DomainRHD
TgeneNFATC1chr18:77478016chr18:77227450ENST00000329101610410_592640931.0DomainRHD
TgeneNFATC1chr18:77478016chr18:77227450ENST00000427363610410_592653944.0DomainRHD
TgeneNFATC1chr18:77478016chr18:77227450ENST0000054238469410_592653714.0DomainRHD
TgeneNFATC1chr18:77478016chr18:77227450ENST0000058643469410_592640701.0DomainRHD
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059181468410_592653717.0DomainRHD
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059222368410_592640704.0DomainRHD
TgeneNFATC1chr18:77478016chr18:77227450ENST00000253506610265_267653826.0MotifNote=Nuclear localization signal
TgeneNFATC1chr18:77478016chr18:77227450ENST00000253506610310_321653826.0MotifNote=Nuclear export signal
TgeneNFATC1chr18:77478016chr18:77227450ENST00000318065610265_267640813.0MotifNote=Nuclear localization signal
TgeneNFATC1chr18:77478016chr18:77227450ENST00000318065610310_321640813.0MotifNote=Nuclear export signal
TgeneNFATC1chr18:77478016chr18:77227450ENST00000329101610265_267640931.0MotifNote=Nuclear localization signal
TgeneNFATC1chr18:77478016chr18:77227450ENST00000329101610310_321640931.0MotifNote=Nuclear export signal
TgeneNFATC1chr18:77478016chr18:77227450ENST00000427363610265_267653944.0MotifNote=Nuclear localization signal
TgeneNFATC1chr18:77478016chr18:77227450ENST00000427363610310_321653944.0MotifNote=Nuclear export signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000054238469265_267653714.0MotifNote=Nuclear localization signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000054238469310_321653714.0MotifNote=Nuclear export signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000058643469265_267640701.0MotifNote=Nuclear localization signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000058643469310_321640701.0MotifNote=Nuclear export signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059181468265_267653717.0MotifNote=Nuclear localization signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059181468310_321653717.0MotifNote=Nuclear export signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059222368265_267640704.0MotifNote=Nuclear localization signal
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059222368310_321640704.0MotifNote=Nuclear export signal
TgeneNFATC1chr18:77478016chr18:77227450ENST00000253506610118_123653826.0RegionNote=Calcineurin-binding
TgeneNFATC1chr18:77478016chr18:77227450ENST00000253506610126_218653826.0RegionNote=Trans-activation domain A (TAD-A)
TgeneNFATC1chr18:77478016chr18:77227450ENST00000253506610203_298653826.0RegionNote=3 X SP repeats
TgeneNFATC1chr18:77478016chr18:77227450ENST00000318065610118_123640813.0RegionNote=Calcineurin-binding
TgeneNFATC1chr18:77478016chr18:77227450ENST00000318065610126_218640813.0RegionNote=Trans-activation domain A (TAD-A)
TgeneNFATC1chr18:77478016chr18:77227450ENST00000318065610203_298640813.0RegionNote=3 X SP repeats
TgeneNFATC1chr18:77478016chr18:77227450ENST00000329101610118_123640931.0RegionNote=Calcineurin-binding
TgeneNFATC1chr18:77478016chr18:77227450ENST00000329101610126_218640931.0RegionNote=Trans-activation domain A (TAD-A)
TgeneNFATC1chr18:77478016chr18:77227450ENST00000329101610203_298640931.0RegionNote=3 X SP repeats
TgeneNFATC1chr18:77478016chr18:77227450ENST0000039779059118_123181354.0RegionNote=Calcineurin-binding
TgeneNFATC1chr18:77478016chr18:77227450ENST0000039779059126_218181354.0RegionNote=Trans-activation domain A (TAD-A)
TgeneNFATC1chr18:77478016chr18:77227450ENST00000427363610118_123653944.0RegionNote=Calcineurin-binding
TgeneNFATC1chr18:77478016chr18:77227450ENST00000427363610126_218653944.0RegionNote=Trans-activation domain A (TAD-A)
TgeneNFATC1chr18:77478016chr18:77227450ENST00000427363610203_298653944.0RegionNote=3 X SP repeats
TgeneNFATC1chr18:77478016chr18:77227450ENST0000054238469118_123653714.0RegionNote=Calcineurin-binding
TgeneNFATC1chr18:77478016chr18:77227450ENST0000054238469126_218653714.0RegionNote=Trans-activation domain A (TAD-A)
TgeneNFATC1chr18:77478016chr18:77227450ENST0000054238469203_298653714.0RegionNote=3 X SP repeats
TgeneNFATC1chr18:77478016chr18:77227450ENST0000058643469118_123640701.0RegionNote=Calcineurin-binding
TgeneNFATC1chr18:77478016chr18:77227450ENST0000058643469126_218640701.0RegionNote=Trans-activation domain A (TAD-A)
TgeneNFATC1chr18:77478016chr18:77227450ENST0000058643469203_298640701.0RegionNote=3 X SP repeats
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059181468118_123653717.0RegionNote=Calcineurin-binding
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059181468126_218653717.0RegionNote=Trans-activation domain A (TAD-A)
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059181468203_298653717.0RegionNote=3 X SP repeats
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059222368118_123640704.0RegionNote=Calcineurin-binding
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059222368126_218640704.0RegionNote=Trans-activation domain A (TAD-A)
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059222368203_298640704.0RegionNote=3 X SP repeats
TgeneNFATC1chr18:77478016chr18:77227450ENST00000253506610203_219653826.0RepeatNote=1
TgeneNFATC1chr18:77478016chr18:77227450ENST00000253506610233_249653826.0RepeatNote=2
TgeneNFATC1chr18:77478016chr18:77227450ENST00000253506610282_298653826.0RepeatNote=3
TgeneNFATC1chr18:77478016chr18:77227450ENST00000318065610203_219640813.0RepeatNote=1
TgeneNFATC1chr18:77478016chr18:77227450ENST00000318065610233_249640813.0RepeatNote=2
TgeneNFATC1chr18:77478016chr18:77227450ENST00000318065610282_298640813.0RepeatNote=3
TgeneNFATC1chr18:77478016chr18:77227450ENST00000329101610203_219640931.0RepeatNote=1
TgeneNFATC1chr18:77478016chr18:77227450ENST00000329101610233_249640931.0RepeatNote=2
TgeneNFATC1chr18:77478016chr18:77227450ENST00000329101610282_298640931.0RepeatNote=3
TgeneNFATC1chr18:77478016chr18:77227450ENST00000427363610203_219653944.0RepeatNote=1
TgeneNFATC1chr18:77478016chr18:77227450ENST00000427363610233_249653944.0RepeatNote=2
TgeneNFATC1chr18:77478016chr18:77227450ENST00000427363610282_298653944.0RepeatNote=3
TgeneNFATC1chr18:77478016chr18:77227450ENST0000054238469203_219653714.0RepeatNote=1
TgeneNFATC1chr18:77478016chr18:77227450ENST0000054238469233_249653714.0RepeatNote=2
TgeneNFATC1chr18:77478016chr18:77227450ENST0000054238469282_298653714.0RepeatNote=3
TgeneNFATC1chr18:77478016chr18:77227450ENST0000058643469203_219640701.0RepeatNote=1
TgeneNFATC1chr18:77478016chr18:77227450ENST0000058643469233_249640701.0RepeatNote=2
TgeneNFATC1chr18:77478016chr18:77227450ENST0000058643469282_298640701.0RepeatNote=3
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059181468203_219653717.0RepeatNote=1
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059181468233_249653717.0RepeatNote=2
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059181468282_298653717.0RepeatNote=3
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059222368203_219640704.0RepeatNote=1
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059222368233_249640704.0RepeatNote=2
TgeneNFATC1chr18:77478016chr18:77227450ENST0000059222368282_298640704.0RepeatNote=3


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Fusion Gene Sequence for CTDP1-NFATC1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>20153_20153_1_CTDP1-NFATC1_CTDP1_chr18_77478016_ENST00000075430_NFATC1_chr18_77227450_ENST00000587635_length(transcript)=2746nt_BP=2519nt
GGAACTACAGCGTCGCCGCCTGGGTTGTGTCGCCGCGGTAGGCGCTGCGCTCTGAGCGCAGCGCAGGCCCCGTACCGACCGCCCGCCCGC
CCTCTGTCCGCGATGGAGGTGCCGGCCGCGGGTCGCGTTCCTGCCGAGGGCGCCCCGACGGCGGCTGTGGCCGAGGTGCGCTGCCCGGGG
CCCGCGCCGCTGCGCCTGCTGGAGTGGAGGGTGGCGGCGGGCGCGGCCGTGCGCATCGGCTCGGTGCTGGCCGTGTTCGAGGCCGCCGCC
TCCGCGCAGTCCTCCGGGGCCTCTCAGTCCCGTGTAGCCTCCGGGGGCTGCGTGCGCCCCGCGCGGCCGGAACGCAGGCTGAGGTCGGAG
CGCGCGGGCGTGGTGCGGGAGCTGTGCGCGCAGCCGGGCCAGGTGGTCGCCCCAGGAGCGGTTCTGGTGAGGTTGGAAGGATGCAGCCAC
CCGGTTGTCATGAAAGGCCTGTGTGCTGAATGTGGCCAAGACCTCACCCAGTTGCAGAGTAAGAACGGGAAGCAGCAGGTGCCGCTGTCC
ACGGCGACCGTGTCCATGGTGCACAGCGTGCCGGAGTTGATGGTGAGCTCCGAGCAAGCTGAACAGCTGGGAAGAGAAGACCAGCAGCGA
CTGCACCGAAACCGGAAGCTGGTGCTCATGGTGGACTTGGACCAGACGTTGATTCACACAACCGAGCAGCACTGTCAGCAGATGTCGAAT
AAAGGCATCTTTCACTTCCAGCTGGGCCGGGGTGAGCCCATGCTGCACACGCGCCTGCGTCCACACTGCAAGGACTTCCTGGAGAAGATC
GCCAAGCTGTACGAGCTGCACGTCTTCACCTTCGGCAGCCGGCTGTACGCACACACCATCGCAGGCTTTTTAGACCCCGAGAAGAAGCTT
TTTTCTCACCGAATATTATCAAGGGATGAATGTATTGACCCATTTTCTAAAACGGGAAACCTTAGAAATCTCTTTCCTTGTGGAGACTCA
ATGGTTTGCATTATTGATGATCGAGAAGATGTCTGGAAGTTTGCCCCCAATCTGATAACTGTGAAGAAATATGTATACTTCCAGGGCACG
GGTGATATGAATGCGCCCCCTGGGTCCCGAGAATCTCAGACGAGAAAGAAAGTAAATCATTCTCGAGGCACTGAGGTCTCAGAGCCATCT
CCGCCCGTGAGAGACCCTGAGGGGGTAACGCAGGCCCCTGGAGTGGAGCCCAGCAATGGCCTGGAGAAGCCTGCACGGGAGCTGAACGGC
AGCGAGGCCGCCACCCCGCGGGACTCACCCCGCCCCGGGAAGCCAGACGAGAGGGACATCTGGCCCCCTGCCCAGGCCCCCACCAGCAGC
CAAGAGCTGGCAGGCGCTCCTGAGCCCCAGGGATCCTGTGCGCAGGGTGGCCGGGTGGCACCGGGACAGCGGCCTGCCCAGGGTGCCACG
GGCACTGACCTGGACTTTGACTTATCCAGCGACAGCGAGAGCAGCAGTGAGTCCGAGGGCACGAAGTCCTCCTCCTCCGCCTCTGATGGC
GAAAGCGAGGGGAAAAGAGGCCGGCAGAAGCCGAAGGCTGCCCCAGAGGGAGCCGGGGCGCTGGCACAGGGCAGTTCCCTGGAGCCGGGG
CGGCCTGCAGCACCGAGTCTCCCCGGAGAGGCCGAGCCTGGCGCGCATGCCCCGGACAAGGAGCCTGAGCTGGGTGGGCAGGAGGAGGGC
GAGCGGGATGGCCTCTGCGGCCTGGGCAACGGCTGTGCCGACAGGAAGGAGGCGGAGACCGAGTCACAGAACAGCGAGCTGTCGGGGGTC
ACTGCGGGTGAGTCCCTGGACCAGAGCATGGAGGAGGAGGAGGAGGAGGACACGGATGAGGATGACCACCTCATCTACCTGGAGGAGATC
CTGGTCCGTGTACACACTGACTACTATGCCAAGTATGACCGCTACCTCAACAAGGAGATCGAGGAGGCGCCGGACATCCGCAAGATCGTG
CCGGAGCTCAAGAGCAAGGTGCTGGCAGACGTGGCCATAATTTTCAGTGGGCTACACCCGACAAACTTCCCGATAGAGAAGACGCGGGAG
CATTACCACGCCACGGCGCTGGGAGCGAAGATCCTCACTCGGCTGGTGCTGAGCCCCGACGCCCCTGACAGGGCCACGCACCTGATCGCC
GCGCGAGCTGGCACAGAGAAGGTGCTGCAGGCACAGGAGTGCGGACACCTGCACGTGGTCAACCCTGACTGGCTGTGGAGCTGCCTGGAG
CGCTGGGACAAGGTGGAGGAGCAGCTCTTCCCGCTCAGGGACGATCACACCAAGGCACAGAGGGAGAACAGCCCTGCGGCCTTTCCCGAC
CGGGAGGGTGTGCCCCCCACCGCCTTGTTCCACCCGATGCCGGTTCTTCCCAAGGCCCAGCCTGGCCCCGAGGTTCGGATCTACGACTCC
AACACGGGGAAGCTCATCAGGACGGGCGCCCGGGGGCCCCCAGCACCCTCCAGCTCCCTACCCATCCGCCAGGAGCCCTCTTCCTTCAGA
ATTCTCTGGTGGTTGAGATCCCGCCATTTCGGAATCAGAGGATAACCAGCCCCGTTCACGTCAGTTTCTACGTCTGCAACGGGAAGAGAA
AGCGAAGCCAGTACCAGCGTTTCACCTACCTTCCCGCCAACGGTAACGCCATCTTTCTAACCGTAAGCCGTGAACATGAGCGCGTGGGGT

>20153_20153_1_CTDP1-NFATC1_CTDP1_chr18_77478016_ENST00000075430_NFATC1_chr18_77227450_ENST00000587635_length(amino acids)=846AA_BP=827
MCRRGRRCALSAAQAPYRPPARPLSAMEVPAAGRVPAEGAPTAAVAEVRCPGPAPLRLLEWRVAAGAAVRIGSVLAVFEAAASAQSSGAS
QSRVASGGCVRPARPERRLRSERAGVVRELCAQPGQVVAPGAVLVRLEGCSHPVVMKGLCAECGQDLTQLQSKNGKQQVPLSTATVSMVH
SVPELMVSSEQAEQLGREDQQRLHRNRKLVLMVDLDQTLIHTTEQHCQQMSNKGIFHFQLGRGEPMLHTRLRPHCKDFLEKIAKLYELHV
FTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECIDPFSKTGNLRNLFPCGDSMVCIIDDREDVWKFAPNLITVKKYVYFQGTGDMNAPPG
SRESQTRKKVNHSRGTEVSEPSPPVRDPEGVTQAPGVEPSNGLEKPARELNGSEAATPRDSPRPGKPDERDIWPPAQAPTSSQELAGAPE
PQGSCAQGGRVAPGQRPAQGATGTDLDFDLSSDSESSSESEGTKSSSSASDGESEGKRGRQKPKAAPEGAGALAQGSSLEPGRPAAPSLP
GEAEPGAHAPDKEPELGGQEEGERDGLCGLGNGCADRKEAETESQNSELSGVTAGESLDQSMEEEEEEDTDEDDHLIYLEEILVRVHTDY
YAKYDRYLNKEIEEAPDIRKIVPELKSKVLADVAIIFSGLHPTNFPIEKTREHYHATALGAKILTRLVLSPDAPDRATHLIAARAGTEKV
LQAQECGHLHVVNPDWLWSCLERWDKVEEQLFPLRDDHTKAQRENSPAAFPDREGVPPTALFHPMPVLPKAQPGPEVRIYDSNTGKLIRT

--------------------------------------------------------------
>20153_20153_2_CTDP1-NFATC1_CTDP1_chr18_77478016_ENST00000075430_NFATC1_chr18_77227450_ENST00000591814_length(transcript)=3072nt_BP=2519nt
GGAACTACAGCGTCGCCGCCTGGGTTGTGTCGCCGCGGTAGGCGCTGCGCTCTGAGCGCAGCGCAGGCCCCGTACCGACCGCCCGCCCGC
CCTCTGTCCGCGATGGAGGTGCCGGCCGCGGGTCGCGTTCCTGCCGAGGGCGCCCCGACGGCGGCTGTGGCCGAGGTGCGCTGCCCGGGG
CCCGCGCCGCTGCGCCTGCTGGAGTGGAGGGTGGCGGCGGGCGCGGCCGTGCGCATCGGCTCGGTGCTGGCCGTGTTCGAGGCCGCCGCC
TCCGCGCAGTCCTCCGGGGCCTCTCAGTCCCGTGTAGCCTCCGGGGGCTGCGTGCGCCCCGCGCGGCCGGAACGCAGGCTGAGGTCGGAG
CGCGCGGGCGTGGTGCGGGAGCTGTGCGCGCAGCCGGGCCAGGTGGTCGCCCCAGGAGCGGTTCTGGTGAGGTTGGAAGGATGCAGCCAC
CCGGTTGTCATGAAAGGCCTGTGTGCTGAATGTGGCCAAGACCTCACCCAGTTGCAGAGTAAGAACGGGAAGCAGCAGGTGCCGCTGTCC
ACGGCGACCGTGTCCATGGTGCACAGCGTGCCGGAGTTGATGGTGAGCTCCGAGCAAGCTGAACAGCTGGGAAGAGAAGACCAGCAGCGA
CTGCACCGAAACCGGAAGCTGGTGCTCATGGTGGACTTGGACCAGACGTTGATTCACACAACCGAGCAGCACTGTCAGCAGATGTCGAAT
AAAGGCATCTTTCACTTCCAGCTGGGCCGGGGTGAGCCCATGCTGCACACGCGCCTGCGTCCACACTGCAAGGACTTCCTGGAGAAGATC
GCCAAGCTGTACGAGCTGCACGTCTTCACCTTCGGCAGCCGGCTGTACGCACACACCATCGCAGGCTTTTTAGACCCCGAGAAGAAGCTT
TTTTCTCACCGAATATTATCAAGGGATGAATGTATTGACCCATTTTCTAAAACGGGAAACCTTAGAAATCTCTTTCCTTGTGGAGACTCA
ATGGTTTGCATTATTGATGATCGAGAAGATGTCTGGAAGTTTGCCCCCAATCTGATAACTGTGAAGAAATATGTATACTTCCAGGGCACG
GGTGATATGAATGCGCCCCCTGGGTCCCGAGAATCTCAGACGAGAAAGAAAGTAAATCATTCTCGAGGCACTGAGGTCTCAGAGCCATCT
CCGCCCGTGAGAGACCCTGAGGGGGTAACGCAGGCCCCTGGAGTGGAGCCCAGCAATGGCCTGGAGAAGCCTGCACGGGAGCTGAACGGC
AGCGAGGCCGCCACCCCGCGGGACTCACCCCGCCCCGGGAAGCCAGACGAGAGGGACATCTGGCCCCCTGCCCAGGCCCCCACCAGCAGC
CAAGAGCTGGCAGGCGCTCCTGAGCCCCAGGGATCCTGTGCGCAGGGTGGCCGGGTGGCACCGGGACAGCGGCCTGCCCAGGGTGCCACG
GGCACTGACCTGGACTTTGACTTATCCAGCGACAGCGAGAGCAGCAGTGAGTCCGAGGGCACGAAGTCCTCCTCCTCCGCCTCTGATGGC
GAAAGCGAGGGGAAAAGAGGCCGGCAGAAGCCGAAGGCTGCCCCAGAGGGAGCCGGGGCGCTGGCACAGGGCAGTTCCCTGGAGCCGGGG
CGGCCTGCAGCACCGAGTCTCCCCGGAGAGGCCGAGCCTGGCGCGCATGCCCCGGACAAGGAGCCTGAGCTGGGTGGGCAGGAGGAGGGC
GAGCGGGATGGCCTCTGCGGCCTGGGCAACGGCTGTGCCGACAGGAAGGAGGCGGAGACCGAGTCACAGAACAGCGAGCTGTCGGGGGTC
ACTGCGGGTGAGTCCCTGGACCAGAGCATGGAGGAGGAGGAGGAGGAGGACACGGATGAGGATGACCACCTCATCTACCTGGAGGAGATC
CTGGTCCGTGTACACACTGACTACTATGCCAAGTATGACCGCTACCTCAACAAGGAGATCGAGGAGGCGCCGGACATCCGCAAGATCGTG
CCGGAGCTCAAGAGCAAGGTGCTGGCAGACGTGGCCATAATTTTCAGTGGGCTACACCCGACAAACTTCCCGATAGAGAAGACGCGGGAG
CATTACCACGCCACGGCGCTGGGAGCGAAGATCCTCACTCGGCTGGTGCTGAGCCCCGACGCCCCTGACAGGGCCACGCACCTGATCGCC
GCGCGAGCTGGCACAGAGAAGGTGCTGCAGGCACAGGAGTGCGGACACCTGCACGTGGTCAACCCTGACTGGCTGTGGAGCTGCCTGGAG
CGCTGGGACAAGGTGGAGGAGCAGCTCTTCCCGCTCAGGGACGATCACACCAAGGCACAGAGGGAGAACAGCCCTGCGGCCTTTCCCGAC
CGGGAGGGTGTGCCCCCCACCGCCTTGTTCCACCCGATGCCGGTTCTTCCCAAGGCCCAGCCTGGCCCCGAGGTTCGGATCTACGACTCC
AACACGGGGAAGCTCATCAGGACGGGCGCCCGGGGGCCCCCAGCACCCTCCAGCTCCCTACCCATCCGCCAGGAGCCCTCTTCCTTCAGA
ATTCTCTGGTGGTTGAGATCCCGCCATTTCGGAATCAGAGGATAACCAGCCCCGTTCACGTCAGTTTCTACGTCTGCAACGGGAAGAGAA
AGCGAAGCCAGTACCAGCGTTTCACCTACCTTCCCGCCAACGGTAACGCCATCTTTCTAACCGTAAGCCGTGAACATGAGCGCGTGGGGT
GCTTTTTCTAAAGACGCAGAAACGACGTCGCCGTAAAGCAGCGTGGCGTGTTGCACATTTAACTGTGTGATGTCCCGTTAGTGAGACCGA
GCCATCGATGCCCTGAAAAGGAAAGGAAAAGGGAAGCTTCGGATGCATTTTCCTTGATCCCTGTTGGGGGTGGGGGGCGGGGGTTGCATA
CTCAGATAGTCACGGTTATTTTGCTTCTTGCGAATGTATAACAGCCAAGGGGAAAACATGGCTCTTCTGCTCCAAAAAACTGAGGGGGTC
CTGGTGTGCATTTGCACCCTAAAGCTGCTTACGGTGAAAAGGCAAATAGGTATAGCTATTTTGCAGGCACCTTTAGGAATAAACTTTGCT

>20153_20153_2_CTDP1-NFATC1_CTDP1_chr18_77478016_ENST00000075430_NFATC1_chr18_77227450_ENST00000591814_length(amino acids)=846AA_BP=827
MCRRGRRCALSAAQAPYRPPARPLSAMEVPAAGRVPAEGAPTAAVAEVRCPGPAPLRLLEWRVAAGAAVRIGSVLAVFEAAASAQSSGAS
QSRVASGGCVRPARPERRLRSERAGVVRELCAQPGQVVAPGAVLVRLEGCSHPVVMKGLCAECGQDLTQLQSKNGKQQVPLSTATVSMVH
SVPELMVSSEQAEQLGREDQQRLHRNRKLVLMVDLDQTLIHTTEQHCQQMSNKGIFHFQLGRGEPMLHTRLRPHCKDFLEKIAKLYELHV
FTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECIDPFSKTGNLRNLFPCGDSMVCIIDDREDVWKFAPNLITVKKYVYFQGTGDMNAPPG
SRESQTRKKVNHSRGTEVSEPSPPVRDPEGVTQAPGVEPSNGLEKPARELNGSEAATPRDSPRPGKPDERDIWPPAQAPTSSQELAGAPE
PQGSCAQGGRVAPGQRPAQGATGTDLDFDLSSDSESSSESEGTKSSSSASDGESEGKRGRQKPKAAPEGAGALAQGSSLEPGRPAAPSLP
GEAEPGAHAPDKEPELGGQEEGERDGLCGLGNGCADRKEAETESQNSELSGVTAGESLDQSMEEEEEEDTDEDDHLIYLEEILVRVHTDY
YAKYDRYLNKEIEEAPDIRKIVPELKSKVLADVAIIFSGLHPTNFPIEKTREHYHATALGAKILTRLVLSPDAPDRATHLIAARAGTEKV
LQAQECGHLHVVNPDWLWSCLERWDKVEEQLFPLRDDHTKAQRENSPAAFPDREGVPPTALFHPMPVLPKAQPGPEVRIYDSNTGKLIRT

--------------------------------------------------------------
>20153_20153_3_CTDP1-NFATC1_CTDP1_chr18_77478016_ENST00000299543_NFATC1_chr18_77227450_ENST00000587635_length(transcript)=2791nt_BP=2564nt
GGAAGTCGGCGCGGGCTAGGCGACGGGTGGAAGCCGGTACCGAGAGGAACTACAGCGTCGCCGCCTGGGTTGTGTCGCCGCGGTAGGCGC
TGCGCTCTGAGCGCAGCGCAGGCCCCGTACCGACCGCCCGCCCGCCCTCTGTCCGCGATGGAGGTGCCGGCCGCGGGTCGCGTTCCTGCC
GAGGGCGCCCCGACGGCGGCTGTGGCCGAGGTGCGCTGCCCGGGGCCCGCGCCGCTGCGCCTGCTGGAGTGGAGGGTGGCGGCGGGCGCG
GCCGTGCGCATCGGCTCGGTGCTGGCCGTGTTCGAGGCCGCCGCCTCCGCGCAGTCCTCCGGGGCCTCTCAGTCCCGTGTAGCCTCCGGG
GGCTGCGTGCGCCCCGCGCGGCCGGAACGCAGGCTGAGGTCGGAGCGCGCGGGCGTGGTGCGGGAGCTGTGCGCGCAGCCGGGCCAGGTG
GTCGCCCCAGGAGCGGTTCTGGTGAGGTTGGAAGGATGCAGCCACCCGGTTGTCATGAAAGGCCTGTGTGCTGAATGTGGCCAAGACCTC
ACCCAGTTGCAGAGTAAGAACGGGAAGCAGCAGGTGCCGCTGTCCACGGCGACCGTGTCCATGGTGCACAGCGTGCCGGAGTTGATGGTG
AGCTCCGAGCAAGCTGAACAGCTGGGAAGAGAAGACCAGCAGCGACTGCACCGAAACCGGAAGCTGGTGCTCATGGTGGACTTGGACCAG
ACGTTGATTCACACAACCGAGCAGCACTGTCAGCAGATGTCGAATAAAGGCATCTTTCACTTCCAGCTGGGCCGGGGTGAGCCCATGCTG
CACACGCGCCTGCGTCCACACTGCAAGGACTTCCTGGAGAAGATCGCCAAGCTGTACGAGCTGCACGTCTTCACCTTCGGCAGCCGGCTG
TACGCACACACCATCGCAGGCTTTTTAGACCCCGAGAAGAAGCTTTTTTCTCACCGAATATTATCAAGGGATGAATGTATTGACCCATTT
TCTAAAACGGGAAACCTTAGAAATCTCTTTCCTTGTGGAGACTCAATGGTTTGCATTATTGATGATCGAGAAGATGTCTGGAAGTTTGCC
CCCAATCTGATAACTGTGAAGAAATATGTATACTTCCAGGGCACGGGTGATATGAATGCGCCCCCTGGGTCCCGAGAATCTCAGACGAGA
AAGAAAGTAAATCATTCTCGAGGCACTGAGGTCTCAGAGCCATCTCCGCCCGTGAGAGACCCTGAGGGGGTAACGCAGGCCCCTGGAGTG
GAGCCCAGCAATGGCCTGGAGAAGCCTGCACGGGAGCTGAACGGCAGCGAGGCCGCCACCCCGCGGGACTCACCCCGCCCCGGGAAGCCA
GACGAGAGGGACATCTGGCCCCCTGCCCAGGCCCCCACCAGCAGCCAAGAGCTGGCAGGCGCTCCTGAGCCCCAGGGATCCTGTGCGCAG
GGTGGCCGGGTGGCACCGGGACAGCGGCCTGCCCAGGGTGCCACGGGCACTGACCTGGACTTTGACTTATCCAGCGACAGCGAGAGCAGC
AGTGAGTCCGAGGGCACGAAGTCCTCCTCCTCCGCCTCTGATGGCGAAAGCGAGGGGAAAAGAGGCCGGCAGAAGCCGAAGGCTGCCCCA
GAGGGAGCCGGGGCGCTGGCACAGGGCAGTTCCCTGGAGCCGGGGCGGCCTGCAGCACCGAGTCTCCCCGGAGAGGCCGAGCCTGGCGCG
CATGCCCCGGACAAGGAGCCTGAGCTGGGTGGGCAGGAGGAGGGCGAGCGGGATGGCCTCTGCGGCCTGGGCAACGGCTGTGCCGACAGG
AAGGAGGCGGAGACCGAGTCACAGAACAGCGAGCTGTCGGGGGTCACTGCGGGTGAGTCCCTGGACCAGAGCATGGAGGAGGAGGAGGAG
GAGGACACGGATGAGGATGACCACCTCATCTACCTGGAGGAGATCCTGGTCCGTGTACACACTGACTACTATGCCAAGTATGACCGCTAC
CTCAACAAGGAGATCGAGGAGGCGCCGGACATCCGCAAGATCGTGCCGGAGCTCAAGAGCAAGGTGCTGGCAGACGTGGCCATAATTTTC
AGTGGGCTACACCCGACAAACTTCCCGATAGAGAAGACGCGGGAGCATTACCACGCCACGGCGCTGGGAGCGAAGATCCTCACTCGGCTG
GTGCTGAGCCCCGACGCCCCTGACAGGGCCACGCACCTGATCGCCGCGCGAGCTGGCACAGAGAAGGTGCTGCAGGCACAGGAGTGCGGA
CACCTGCACGTGGTCAACCCTGACTGGCTGTGGAGCTGCCTGGAGCGCTGGGACAAGGTGGAGGAGCAGCTCTTCCCGCTCAGGGACGAT
CACACCAAGGCACAGAGGGAGAACAGCCCTGCGGCCTTTCCCGACCGGGAGGGTGTGCCCCCCACCGCCTTGTTCCACCCGATGCCGGTT
CTTCCCAAGGCCCAGCCTGGCCCCGAGGTTCGGATCTACGACTCCAACACGGGGAAGCTCATCAGGACGGGCGCCCGGGGGCCCCCAGCA
CCCTCCAGCTCCCTACCCATCCGCCAGGAGCCCTCTTCCTTCAGAATTCTCTGGTGGTTGAGATCCCGCCATTTCGGAATCAGAGGATAA
CCAGCCCCGTTCACGTCAGTTTCTACGTCTGCAACGGGAAGAGAAAGCGAAGCCAGTACCAGCGTTTCACCTACCTTCCCGCCAACGGTA
ACGCCATCTTTCTAACCGTAAGCCGTGAACATGAGCGCGTGGGGTGCTTTTTCTAAAGACGCAGAAACGACGTCGCCGTAAAGCAGCGTG

>20153_20153_3_CTDP1-NFATC1_CTDP1_chr18_77478016_ENST00000299543_NFATC1_chr18_77227450_ENST00000587635_length(amino acids)=846AA_BP=827
MCRRGRRCALSAAQAPYRPPARPLSAMEVPAAGRVPAEGAPTAAVAEVRCPGPAPLRLLEWRVAAGAAVRIGSVLAVFEAAASAQSSGAS
QSRVASGGCVRPARPERRLRSERAGVVRELCAQPGQVVAPGAVLVRLEGCSHPVVMKGLCAECGQDLTQLQSKNGKQQVPLSTATVSMVH
SVPELMVSSEQAEQLGREDQQRLHRNRKLVLMVDLDQTLIHTTEQHCQQMSNKGIFHFQLGRGEPMLHTRLRPHCKDFLEKIAKLYELHV
FTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECIDPFSKTGNLRNLFPCGDSMVCIIDDREDVWKFAPNLITVKKYVYFQGTGDMNAPPG
SRESQTRKKVNHSRGTEVSEPSPPVRDPEGVTQAPGVEPSNGLEKPARELNGSEAATPRDSPRPGKPDERDIWPPAQAPTSSQELAGAPE
PQGSCAQGGRVAPGQRPAQGATGTDLDFDLSSDSESSSESEGTKSSSSASDGESEGKRGRQKPKAAPEGAGALAQGSSLEPGRPAAPSLP
GEAEPGAHAPDKEPELGGQEEGERDGLCGLGNGCADRKEAETESQNSELSGVTAGESLDQSMEEEEEEDTDEDDHLIYLEEILVRVHTDY
YAKYDRYLNKEIEEAPDIRKIVPELKSKVLADVAIIFSGLHPTNFPIEKTREHYHATALGAKILTRLVLSPDAPDRATHLIAARAGTEKV
LQAQECGHLHVVNPDWLWSCLERWDKVEEQLFPLRDDHTKAQRENSPAAFPDREGVPPTALFHPMPVLPKAQPGPEVRIYDSNTGKLIRT

--------------------------------------------------------------
>20153_20153_4_CTDP1-NFATC1_CTDP1_chr18_77478016_ENST00000299543_NFATC1_chr18_77227450_ENST00000591814_length(transcript)=3117nt_BP=2564nt
GGAAGTCGGCGCGGGCTAGGCGACGGGTGGAAGCCGGTACCGAGAGGAACTACAGCGTCGCCGCCTGGGTTGTGTCGCCGCGGTAGGCGC
TGCGCTCTGAGCGCAGCGCAGGCCCCGTACCGACCGCCCGCCCGCCCTCTGTCCGCGATGGAGGTGCCGGCCGCGGGTCGCGTTCCTGCC
GAGGGCGCCCCGACGGCGGCTGTGGCCGAGGTGCGCTGCCCGGGGCCCGCGCCGCTGCGCCTGCTGGAGTGGAGGGTGGCGGCGGGCGCG
GCCGTGCGCATCGGCTCGGTGCTGGCCGTGTTCGAGGCCGCCGCCTCCGCGCAGTCCTCCGGGGCCTCTCAGTCCCGTGTAGCCTCCGGG
GGCTGCGTGCGCCCCGCGCGGCCGGAACGCAGGCTGAGGTCGGAGCGCGCGGGCGTGGTGCGGGAGCTGTGCGCGCAGCCGGGCCAGGTG
GTCGCCCCAGGAGCGGTTCTGGTGAGGTTGGAAGGATGCAGCCACCCGGTTGTCATGAAAGGCCTGTGTGCTGAATGTGGCCAAGACCTC
ACCCAGTTGCAGAGTAAGAACGGGAAGCAGCAGGTGCCGCTGTCCACGGCGACCGTGTCCATGGTGCACAGCGTGCCGGAGTTGATGGTG
AGCTCCGAGCAAGCTGAACAGCTGGGAAGAGAAGACCAGCAGCGACTGCACCGAAACCGGAAGCTGGTGCTCATGGTGGACTTGGACCAG
ACGTTGATTCACACAACCGAGCAGCACTGTCAGCAGATGTCGAATAAAGGCATCTTTCACTTCCAGCTGGGCCGGGGTGAGCCCATGCTG
CACACGCGCCTGCGTCCACACTGCAAGGACTTCCTGGAGAAGATCGCCAAGCTGTACGAGCTGCACGTCTTCACCTTCGGCAGCCGGCTG
TACGCACACACCATCGCAGGCTTTTTAGACCCCGAGAAGAAGCTTTTTTCTCACCGAATATTATCAAGGGATGAATGTATTGACCCATTT
TCTAAAACGGGAAACCTTAGAAATCTCTTTCCTTGTGGAGACTCAATGGTTTGCATTATTGATGATCGAGAAGATGTCTGGAAGTTTGCC
CCCAATCTGATAACTGTGAAGAAATATGTATACTTCCAGGGCACGGGTGATATGAATGCGCCCCCTGGGTCCCGAGAATCTCAGACGAGA
AAGAAAGTAAATCATTCTCGAGGCACTGAGGTCTCAGAGCCATCTCCGCCCGTGAGAGACCCTGAGGGGGTAACGCAGGCCCCTGGAGTG
GAGCCCAGCAATGGCCTGGAGAAGCCTGCACGGGAGCTGAACGGCAGCGAGGCCGCCACCCCGCGGGACTCACCCCGCCCCGGGAAGCCA
GACGAGAGGGACATCTGGCCCCCTGCCCAGGCCCCCACCAGCAGCCAAGAGCTGGCAGGCGCTCCTGAGCCCCAGGGATCCTGTGCGCAG
GGTGGCCGGGTGGCACCGGGACAGCGGCCTGCCCAGGGTGCCACGGGCACTGACCTGGACTTTGACTTATCCAGCGACAGCGAGAGCAGC
AGTGAGTCCGAGGGCACGAAGTCCTCCTCCTCCGCCTCTGATGGCGAAAGCGAGGGGAAAAGAGGCCGGCAGAAGCCGAAGGCTGCCCCA
GAGGGAGCCGGGGCGCTGGCACAGGGCAGTTCCCTGGAGCCGGGGCGGCCTGCAGCACCGAGTCTCCCCGGAGAGGCCGAGCCTGGCGCG
CATGCCCCGGACAAGGAGCCTGAGCTGGGTGGGCAGGAGGAGGGCGAGCGGGATGGCCTCTGCGGCCTGGGCAACGGCTGTGCCGACAGG
AAGGAGGCGGAGACCGAGTCACAGAACAGCGAGCTGTCGGGGGTCACTGCGGGTGAGTCCCTGGACCAGAGCATGGAGGAGGAGGAGGAG
GAGGACACGGATGAGGATGACCACCTCATCTACCTGGAGGAGATCCTGGTCCGTGTACACACTGACTACTATGCCAAGTATGACCGCTAC
CTCAACAAGGAGATCGAGGAGGCGCCGGACATCCGCAAGATCGTGCCGGAGCTCAAGAGCAAGGTGCTGGCAGACGTGGCCATAATTTTC
AGTGGGCTACACCCGACAAACTTCCCGATAGAGAAGACGCGGGAGCATTACCACGCCACGGCGCTGGGAGCGAAGATCCTCACTCGGCTG
GTGCTGAGCCCCGACGCCCCTGACAGGGCCACGCACCTGATCGCCGCGCGAGCTGGCACAGAGAAGGTGCTGCAGGCACAGGAGTGCGGA
CACCTGCACGTGGTCAACCCTGACTGGCTGTGGAGCTGCCTGGAGCGCTGGGACAAGGTGGAGGAGCAGCTCTTCCCGCTCAGGGACGAT
CACACCAAGGCACAGAGGGAGAACAGCCCTGCGGCCTTTCCCGACCGGGAGGGTGTGCCCCCCACCGCCTTGTTCCACCCGATGCCGGTT
CTTCCCAAGGCCCAGCCTGGCCCCGAGGTTCGGATCTACGACTCCAACACGGGGAAGCTCATCAGGACGGGCGCCCGGGGGCCCCCAGCA
CCCTCCAGCTCCCTACCCATCCGCCAGGAGCCCTCTTCCTTCAGAATTCTCTGGTGGTTGAGATCCCGCCATTTCGGAATCAGAGGATAA
CCAGCCCCGTTCACGTCAGTTTCTACGTCTGCAACGGGAAGAGAAAGCGAAGCCAGTACCAGCGTTTCACCTACCTTCCCGCCAACGGTA
ACGCCATCTTTCTAACCGTAAGCCGTGAACATGAGCGCGTGGGGTGCTTTTTCTAAAGACGCAGAAACGACGTCGCCGTAAAGCAGCGTG
GCGTGTTGCACATTTAACTGTGTGATGTCCCGTTAGTGAGACCGAGCCATCGATGCCCTGAAAAGGAAAGGAAAAGGGAAGCTTCGGATG
CATTTTCCTTGATCCCTGTTGGGGGTGGGGGGCGGGGGTTGCATACTCAGATAGTCACGGTTATTTTGCTTCTTGCGAATGTATAACAGC
CAAGGGGAAAACATGGCTCTTCTGCTCCAAAAAACTGAGGGGGTCCTGGTGTGCATTTGCACCCTAAAGCTGCTTACGGTGAAAAGGCAA

>20153_20153_4_CTDP1-NFATC1_CTDP1_chr18_77478016_ENST00000299543_NFATC1_chr18_77227450_ENST00000591814_length(amino acids)=846AA_BP=827
MCRRGRRCALSAAQAPYRPPARPLSAMEVPAAGRVPAEGAPTAAVAEVRCPGPAPLRLLEWRVAAGAAVRIGSVLAVFEAAASAQSSGAS
QSRVASGGCVRPARPERRLRSERAGVVRELCAQPGQVVAPGAVLVRLEGCSHPVVMKGLCAECGQDLTQLQSKNGKQQVPLSTATVSMVH
SVPELMVSSEQAEQLGREDQQRLHRNRKLVLMVDLDQTLIHTTEQHCQQMSNKGIFHFQLGRGEPMLHTRLRPHCKDFLEKIAKLYELHV
FTFGSRLYAHTIAGFLDPEKKLFSHRILSRDECIDPFSKTGNLRNLFPCGDSMVCIIDDREDVWKFAPNLITVKKYVYFQGTGDMNAPPG
SRESQTRKKVNHSRGTEVSEPSPPVRDPEGVTQAPGVEPSNGLEKPARELNGSEAATPRDSPRPGKPDERDIWPPAQAPTSSQELAGAPE
PQGSCAQGGRVAPGQRPAQGATGTDLDFDLSSDSESSSESEGTKSSSSASDGESEGKRGRQKPKAAPEGAGALAQGSSLEPGRPAAPSLP
GEAEPGAHAPDKEPELGGQEEGERDGLCGLGNGCADRKEAETESQNSELSGVTAGESLDQSMEEEEEEDTDEDDHLIYLEEILVRVHTDY
YAKYDRYLNKEIEEAPDIRKIVPELKSKVLADVAIIFSGLHPTNFPIEKTREHYHATALGAKILTRLVLSPDAPDRATHLIAARAGTEKV
LQAQECGHLHVVNPDWLWSCLERWDKVEEQLFPLRDDHTKAQRENSPAAFPDREGVPPTALFHPMPVLPKAQPGPEVRIYDSNTGKLIRT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CTDP1-NFATC1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CTDP1-NFATC1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CTDP1-NFATC1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource