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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CTDSP2-COL15A1 (FusionGDB2 ID:20167)

Fusion Gene Summary for CTDSP2-COL15A1

check button Fusion gene summary
Fusion gene informationFusion gene name: CTDSP2-COL15A1
Fusion gene ID: 20167
HgeneTgene
Gene symbol

CTDSP2

COL15A1

Gene ID

10106

1306

Gene nameCTD small phosphatase 2collagen type XV alpha 1 chain
SynonymsOS4|PSR2|SCP2-
Cytomap

12q14.1

9q22.33

Type of geneprotein-codingprotein-coding
Descriptioncarboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2NLI-interacting factor 2conserved gene amplified in osteosarcomanuclear LIM interactor-interacollagen alpha-1(XV) chaincollagen XV, alpha-1 polypeptidecollagen type XV proteoglycancollagen, type XV, alpha 1endostatin-XVrestin
Modification date2020031320200313
UniProtAcc

O14595

P39059

Ensembl transtripts involved in fusion geneENST00000398073, ENST00000548823, 
ENST00000547701, 		ENST00000467052, 
ENST00000375001, 
Fusion gene scores* DoF score32 X 8 X 10=25606 X 7 X 3=126
# samples 377
** MAII scorelog2(37/2560*10)=-2.79054663437105
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/126*10)=-0.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CTDSP2 [Title/Abstract] AND COL15A1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCTDSP2(58240155)-COL15A1(101759216), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCTDSP2

GO:0006470

protein dephosphorylation

12721286


check buttonFusion gene breakpoints across CTDSP2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across COL15A1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LGGTCGA-IK-7675-01ACTDSP2chr12

58240155

-COL15A1chr9

101759216

+
ChimerDB4LGGTCGA-IK-7675CTDSP2chr12

58240154

-COL15A1chr9

101759215

+
ChimerDB4LGGTCGA-IK-7675CTDSP2chr12

58240155

-COL15A1chr9

101759216

+


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Fusion Gene ORF analysis for CTDSP2-COL15A1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000398073ENST00000467052CTDSP2chr12

58240155

-COL15A1chr9

101759216

+
5CDS-intronENST00000398073ENST00000467052CTDSP2chr12

58240154

-COL15A1chr9

101759215

+
5CDS-intronENST00000548823ENST00000467052CTDSP2chr12

58240155

-COL15A1chr9

101759216

+
5CDS-intronENST00000548823ENST00000467052CTDSP2chr12

58240154

-COL15A1chr9

101759215

+
In-frameENST00000398073ENST00000375001CTDSP2chr12

58240155

-COL15A1chr9

101759216

+
In-frameENST00000398073ENST00000375001CTDSP2chr12

58240154

-COL15A1chr9

101759215

+
In-frameENST00000548823ENST00000375001CTDSP2chr12

58240155

-COL15A1chr9

101759216

+
In-frameENST00000548823ENST00000375001CTDSP2chr12

58240154

-COL15A1chr9

101759215

+
intron-3CDSENST00000547701ENST00000375001CTDSP2chr12

58240155

-COL15A1chr9

101759216

+
intron-3CDSENST00000547701ENST00000375001CTDSP2chr12

58240154

-COL15A1chr9

101759215

+
intron-intronENST00000547701ENST00000467052CTDSP2chr12

58240155

-COL15A1chr9

101759216

+
intron-intronENST00000547701ENST00000467052CTDSP2chr12

58240154

-COL15A1chr9

101759215

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000398073CTDSP2chr1258240155-ENST00000375001COL15A1chr9101759216+463236818537301181
ENST00000548823CTDSP2chr1258240155-ENST00000375001COL15A1chr9101759216+459733315036951181
ENST00000398073CTDSP2chr1258240154-ENST00000375001COL15A1chr9101759215+463236818537301181
ENST00000548823CTDSP2chr1258240154-ENST00000375001COL15A1chr9101759215+459733315036951181

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000398073ENST00000375001CTDSP2chr1258240155-COL15A1chr9101759216+0.0017266430.9982734
ENST00000548823ENST00000375001CTDSP2chr1258240155-COL15A1chr9101759216+0.0016992610.99830073
ENST00000398073ENST00000375001CTDSP2chr1258240154-COL15A1chr9101759215+0.0017266430.9982734
ENST00000548823ENST00000375001CTDSP2chr1258240154-COL15A1chr9101759215+0.0016992610.99830073

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Fusion Genomic Features for CTDSP2-COL15A1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CTDSP2chr1258240154-COL15A1chr9101759215+5.72E-060.9999943
CTDSP2chr1258240154-COL15A1chr9101759215+5.72E-060.9999943
CTDSP2chr1258240154-COL15A1chr9101759215+5.72E-060.9999943
CTDSP2chr1258240154-COL15A1chr9101759215+5.72E-060.9999943

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CTDSP2-COL15A1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:58240155/chr9:101759216)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CTDSP2

O14595

COL15A1

P39059

FUNCTION: Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas. {ECO:0000269|PubMed:12721286, ECO:0000269|PubMed:15681389}.FUNCTION: Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle. {ECO:0000269|PubMed:10049780}.; FUNCTION: Restin potently inhibits angiogenesis. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442619_6802681389.0DomainNote=Collagen-like 1
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442681_7312681389.0DomainNote=Collagen-like 2
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442823_8652681389.0DomainNote=Collagen-like 3
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442879_9272681389.0DomainNote=Collagen-like 4
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442619_6802681389.0DomainNote=Collagen-like 1
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442681_7312681389.0DomainNote=Collagen-like 2
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442823_8652681389.0DomainNote=Collagen-like 3
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442879_9272681389.0DomainNote=Collagen-like 4
TgeneCOL15A1chr12:58240154chr9:101759215ENST000003750014421014_10272681389.0RegionNote=Nonhelical region 7 (NC7)
TgeneCOL15A1chr12:58240154chr9:101759215ENST000003750014421028_10452681389.0RegionNote=Triple-helical region 7 (COL7)
TgeneCOL15A1chr12:58240154chr9:101759215ENST000003750014421046_10522681389.0RegionNote=Nonhelical region 8 (NC8)
TgeneCOL15A1chr12:58240154chr9:101759215ENST000003750014421053_11072681389.0RegionNote=Triple-helical region 8 (COL8)
TgeneCOL15A1chr12:58240154chr9:101759215ENST000003750014421108_11172681389.0RegionNote=Nonhelical region 9 (NC9)
TgeneCOL15A1chr12:58240154chr9:101759215ENST000003750014421118_11322681389.0RegionNote=Triple-helical region 9 (COL9)
TgeneCOL15A1chr12:58240154chr9:101759215ENST000003750014421133_13882681389.0RegionNote=Nonhelical region 10 (NC10)
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442358_5552681389.0RegionNote=4 X tandem repeats
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442556_5732681389.0RegionNote=Triple-helical region 1 (COL1)
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442574_6182681389.0RegionNote=Nonhelical region 2 (NC2)
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442619_7322681389.0RegionNote=Triple-helical region 2 (COL2)
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442733_7632681389.0RegionNote=Nonhelical region 3 (NC3)
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442764_7982681389.0RegionNote=Triple-helical region 3 (COL3)
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442799_8222681389.0RegionNote=Nonhelical region 4 (NC4)
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442823_8672681389.0RegionNote=Triple-helical region 4 (COL4)
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442868_8782681389.0RegionNote=Nonhelical region 5 (NC5)
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442879_9492681389.0RegionNote=Triple-helical region 5 (COL5)
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442950_9832681389.0RegionNote=Nonhelical region 6 (NC6)
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442984_10132681389.0RegionNote=Triple-helical region 6 (COL6)
TgeneCOL15A1chr12:58240155chr9:101759216ENST000003750014421014_10272681389.0RegionNote=Nonhelical region 7 (NC7)
TgeneCOL15A1chr12:58240155chr9:101759216ENST000003750014421028_10452681389.0RegionNote=Triple-helical region 7 (COL7)
TgeneCOL15A1chr12:58240155chr9:101759216ENST000003750014421046_10522681389.0RegionNote=Nonhelical region 8 (NC8)
TgeneCOL15A1chr12:58240155chr9:101759216ENST000003750014421053_11072681389.0RegionNote=Triple-helical region 8 (COL8)
TgeneCOL15A1chr12:58240155chr9:101759216ENST000003750014421108_11172681389.0RegionNote=Nonhelical region 9 (NC9)
TgeneCOL15A1chr12:58240155chr9:101759216ENST000003750014421118_11322681389.0RegionNote=Triple-helical region 9 (COL9)
TgeneCOL15A1chr12:58240155chr9:101759216ENST000003750014421133_13882681389.0RegionNote=Nonhelical region 10 (NC10)
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442358_5552681389.0RegionNote=4 X tandem repeats
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442556_5732681389.0RegionNote=Triple-helical region 1 (COL1)
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442574_6182681389.0RegionNote=Nonhelical region 2 (NC2)
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442619_7322681389.0RegionNote=Triple-helical region 2 (COL2)
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442733_7632681389.0RegionNote=Nonhelical region 3 (NC3)
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442764_7982681389.0RegionNote=Triple-helical region 3 (COL3)
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442799_8222681389.0RegionNote=Nonhelical region 4 (NC4)
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442823_8672681389.0RegionNote=Triple-helical region 4 (COL4)
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442868_8782681389.0RegionNote=Nonhelical region 5 (NC5)
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442879_9492681389.0RegionNote=Triple-helical region 5 (COL5)
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442950_9832681389.0RegionNote=Nonhelical region 6 (NC6)
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442984_10132681389.0RegionNote=Triple-helical region 6 (COL6)
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442358_4082681389.0RepeatNote=1
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442409_4592681389.0RepeatNote=2
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442460_5092681389.0RepeatNote=3
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442510_5552681389.0RepeatNote=4
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442358_4082681389.0RepeatNote=1
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442409_4592681389.0RepeatNote=2
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442460_5092681389.0RepeatNote=3
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442510_5552681389.0RepeatNote=4

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCTDSP2chr12:58240154chr9:101759215ENST00000398073-1897_25521272.0DomainFCP1 homology
HgeneCTDSP2chr12:58240155chr9:101759216ENST00000398073-1897_25521272.0DomainFCP1 homology
TgeneCOL15A1chr12:58240154chr9:101759215ENST0000037500144266_2492681389.0DomainNote=Laminin G-like
TgeneCOL15A1chr12:58240155chr9:101759216ENST0000037500144266_2492681389.0DomainNote=Laminin G-like
TgeneCOL15A1chr12:58240154chr9:101759215ENST00000375001442229_5552681389.0RegionNote=Nonhelical region 1 (NC1)
TgeneCOL15A1chr12:58240155chr9:101759216ENST00000375001442229_5552681389.0RegionNote=Nonhelical region 1 (NC1)


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Fusion Gene Sequence for CTDSP2-COL15A1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>20167_20167_1_CTDSP2-COL15A1_CTDSP2_chr12_58240154_ENST00000398073_COL15A1_chr9_101759215_ENST00000375001_length(transcript)=4632nt_BP=368nt
CCATTTCCTCCTCTTGTTTTCGCTCCGGATTCTCCATGTTGGACCCAAACTGAGGAGCCCGGAGCTGCCGCTGGGGGATCGGGGCCGGGG
GCACCCGGGGGAGCCGCTGCCCGGGCCGCCCGCCCTTTGTACAGGCCGCCTCCCTTCCCGGTCCGGGGAGGAAACGAGAGGGGGGATGTG
AACAGCTGTGGAAGTCGGAGTCTCGGGAGCCGGAGCGGGCCCCCGCCCAGGCCCCCCAGCCCAGCCCAGCCCGCGCGCCCGCCCGTCCTC
CCGCCCAGCCAGCCCGGGCCCGCGGGATTGTTAGATGGAACACGGCTCCATCATCACCCAGGCGCGGAGGGAAGACGCCCTGGTGCTCAC
CAAGCAAGCCCAAAGAAGCAAAAGTTGAACCCATAAACACACCTCCAACTCCATCCTCCCCCTTTGAAGACATGGAACTTTCTGGTGAAC
CTGTACCCGAGGGGACCCTGGAAACCACCAACATGAGCATCATCCAGCACAGCAGCCCCAAACAAGGGTCTGGTGAGATCCTGAATGACA
CACTGGAGGGGGTTCATTCTGTGGATGGTGACCCCATTACTGACAGCGGCTCAGGGGCTGGGGCCTTCCTTGACATTGCTGAAGAAAAGA
ATTTAGCAGCAACAGCAGCGGGGCTGGCCGAGGTGCCCATCAGCACTGCTGGAGAAGCAGAGGCCAGCAGTGTGCCCACCGGGGGACCAA
CCCTCTCTATGTCCACGGAGAACCCAGAGGAAGGGGTCACTCCAGGTCCAGATAATGAAGAGCGTTTAGCAGCAACAGCAGCAGGGGAGG
CCGAGGCACTCGCCAGCATGCCTGGGGAAGTGGAGGCCAGTGGTGTGGCCCCCGGGGAGCTGGACCTCTCCATGTCCGCCCAGAGCCTCG
GGGAAGAGGCCACTGTGGGTCCAAGCAGTGAAGACAGTTTAACAACAGCTGCAGCTGCAACCGAAGTGTCCCTCAGTACTTTTGAGGATG
AGGAAGCCAGTGGGGTCCCCACAGATGGCCTGGCTCCCCTCACAGCCACCATGGCCCCTGAGCGGGCAGTCACTTCTGGTCCTGGTGATG
AAGAAGACTTGGCAGCAGCCACAACAGAGGAGCCCCTCATCACAGCTGGGGGTGAAGAGTCCGGCAGCCCTCCCCCTGATGGGCCACCGC
TGCCCCTGCCCACAGTGGCTCCTGAAAGATGGATCACTCCAGCTCAAAGAGAACATGTGGGAATGAAAGGACAGGCTGGGCCCAAAGGAG
AAAAGGGTGATGCTGGGGAGGAGCTTCCTGGCCCTCCTGAACCTTCTGGGCCTGTTGGACCCACGGCAGGAGCAGAAGCAGAGGGCTCTG
GCCTAGGCTGGGGCTCGGACGTCGGCTCTGGCTCTGGTGACCTGGTGGGCAGTGAGCAGCTGCTGAGAGGTCCTCCAGGACCCCCAGGGC
CACCTGGCTTACCTGGGATTCCAGGAAAACCAGGAACTGATGTTTTCATGGGACCCCCTGGATCTCCTGGAGAGGATGGACCTGCTGGTG
AACCTGGGCCCCCGGGCCCTGAGGGACAGCCTGGAGTTGATGGAGCCACCGGCCTTCCCGGGATGAAAGGGGAGAAGGGAGCAAGAGGGC
CTAATGGCTCAGTTGGTGAAAAGGGTGACCCTGGCAACAGAGGCTTACCTGGACCCCCGGGGAAAAAGGGACAAGCTGGCCCTCCTGGGG
TCATGGGACCCCCAGGGCCTCCTGGACCCCCTGGGCCCCCAGGCCCTGGATGCACAATGGGACTTGGATTCGAGGATACCGAAGGCTCTG
GAAGCACCCAGCTATTGAATGAACCCAAACTCTCCAGACCAACGGCTGCAATTGGTCTCAAAGGAGAGAAAGGAGACCGGGGACCCAAGG
GAGAAAGGGGGATGGATGGAGCCAGTATTGTGGGACCCCCTGGGCCGAGAGGGCCACCTGGGCACATCAAGGTCTTGTCTAATTCCTTGA
TCAATATCACCCATGGATTCATGAATTTCTCGGACATTCCTGAGCTGGTGGGGCCTCCGGGGCCGGACGGGTTGCCTGGGCTGCCAGGAT
TTCCAGGTCCTAGAGGACCAAAAGGTGACACTGGTTTACCTGGCTTTCCAGGACTAAAAGGAGAACAGGGCGAGAAGGGAGAGCCGGGTG
CCATCCTGACAGAGGACATTCCTCTGGAAAGGCTGATGGGGAAAAAGGGTGAACCTGGAATGCATGGAGCCCCAGGACCAATGGGGCCCA
AAGGACCACCAGGACATAAAGGAGAATTTGGCCTTCCCGGGCGACCTGGTCGCCCAGGACTGAATGGCCTCAAGGGTACCAAAGGAGATC
CAGGGGTCATTATGCAGGGCCCACCTGGCTTACCTGGCCCTCCAGGCCCCCCTGGGCCACCTGGAGCTGTGATTAACATCAAAGGAGCCA
TTTTCCCAATACCCGTCCGACCACACTGCAAAATGCCAGTTGATACTGCTCATCCTGGGAGTCCAGAGCTCATCACTTTTCACGGTGTTA
AAGGAGAGAAAGGATCCTGGGGTCTTCCTGGCTCAAAGGGAGAAAAAGGCGACCAGGGAGCCCAGGGACCACCAGGTCCTCCACTTGATC
TAGCTTACCTGAGACACTTTCTGAACAACTTGAAGGGGGAGAATGGAGACAAGGGGTTCAAAGGTGAAAAAGGAGAAAAAGGAGACATTA
ATGGCAGCTTCCTTATGTCTGGGCCTCCAGGCCTGCCCGGAAATCCAGGCCCGGCTGGCCAAAAAGGGGAGACAGTCGTTGGGCCCCAAG
GACCCCCAGGTGCTCCTGGTCTGCCTGGGCCACCTGGCTTTGGAAGACCTGGTGATCCTGGGCCACCGGGGCCCCCGGGGCCACCAGGAC
CTCCAGCTATCCTGGGAGCAGCTGTGGCCCTTCCAGGTCCCCCTGGCCCTCCAGGACAGCCAGGGCTTCCCGGATCCAGAAACCTGGTCA
CAGCATTCAGCAACATGGATGACATGCTGCAGAAAGCGCATTTGGTTATAGAAGGAACATTCATCTACCTGAGGGACAGCACTGAGTTTT
TCATTCGTGTTAGAGATGGCTGGAAAAAATTACAGCTGGGAGAACTGATCCCCATTCCTGCCGACAGCCCTCCACCCCCTGCGCTTTCCA
GCAACCCACATCAGCTTCTGCCTCCACCAAACCCTATTTCAAGTGCCAATTATGAGAAGCCTGCTCTGCATTTGGCTGCTCTGAACATGC
CATTTTCTGGGGACATTCGAGCTGATTTTCAGTGCTTCAAGCAGGCCAGAGCTGCAGGACTGTTGTCCACCTACCGAGCATTCTTATCTT
CCCATTTGCAAGATCTGTCCACCATTGTGAGGAAAGCAGAGAGATACAGCCTTCCCATAGTGAACCTCAAGGGCCAAGTACTTTTTAATA
ATTGGGACTCAATTTTTTCTGGCCACGGAGGTCAGTTCAATATGCATATTCCAATATACTCCTTTGATGGTCGAGACATAATGACAGATC
CTTCTTGGCCCCAGAAAGTCATTTGGCATGGCTCCAGCCCCCATGGCGTCCGCCTTGTGGATAACTACTGTGAAGCATGGCGAACCGCGG
ACACAGCGGTCACGGGACTTGCCTCCCCGCTGAGCACGGGGAAGATTCTGGACCAGAAAGCATACAGCTGTGCTAATCGGCTAATTGTCC
TATGTATCGAAAACAGTTTCATGACAGACGCTAGGAAGTAATGGCCTTCTGATGATTCTTAAAGAGTTTTCAATTTTTTCTTATGTGAAG
AGTTGACACTGAAATCTAAAATGTTTAATTGTTGTAAATATTACAGTTTTTTTTTTTTACTACATATTCTTTACAACAGCAACCAAAGAA
AACATACCTCAATACACTCAAAACTGAAGACATAGAGGACTCAGATCAAAGACAAAATCTGATCCATATATTGGTGCTAGATTCTGCAGG
AAACCCCAGCAGTGTGAACGCATCCCAACATAGGTTAAGAGCAAGTTGAAAACAAAGGCCATGGCATTCTGCCACTGCATCCTTCAGACA
GTTATATCCTCCTTTTAAACCATTGTTGTTGAGTGTAAGATGTCCTTCATGTTTTCTTATAAAGTCAGTGTTTAGAAATGTTACCCTTTC
TAAGTTATATACAGATCAAATGCTTTTTTCTTTCACGTACATCCATCATTTGCAACTGCTGTTCGTACACAGAAACAGGACTGCTCAAAT
GATCCTATTTGTATTTTCTGATGCTATCAGACTCTAATGTTTTTTTCCCTAAAATATTATTGCCATCATGCTTTAGGAATTTTATATTTT
TACACAATCATATTTTAGTATGGTGTCTGTTTATGTAACTCTGACTTGCTGGAAAAGTTGAAACTCCAAATAATCTGAAACTAGAAAAGA
AATAGCACATAATTACTACCTTCCCCTTGGCGGCTCTCCTCCCCAACCCCCACCCCACAATTTTATGACTTCCATTTGGCAATTGTTGAA
TTATAACTGCGACTGAAACAAACAGGTTCATAGAGATGAATTTTCTGAGAAACATATATCTACATGTTGTATAATTGGATTTTTTTTCCA

>20167_20167_1_CTDSP2-COL15A1_CTDSP2_chr12_58240154_ENST00000398073_COL15A1_chr9_101759215_ENST00000375001_length(amino acids)=1181AA_BP=487
MWKSESREPERAPAQAPQPSPARAPARPPAQPARARGIVRWNTAPSSPRRGGKTPWCSPSKPKEAKVEPINTPPTPSSPFEDMELSGEPV
PEGTLETTNMSIIQHSSPKQGSGEILNDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAATAAGLAEVPISTAGEAEASSVPTGGPTL
SMSTENPEEGVTPGPDNEERLAATAAGEAEALASMPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEE
ASGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEK
GDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEP
GPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGS
TQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFP
GPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPG
VIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLA
YLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGPP
AILGAAVALPGPPGPPGQPGLPGSRNLVTAFSNMDDMLQKAHLVIEGTFIYLRDSTEFFIRVRDGWKKLQLGELIPIPADSPPPPALSSN
PHQLLPPPNPISSANYEKPALHLAALNMPFSGDIRADFQCFKQARAAGLLSTYRAFLSSHLQDLSTIVRKAERYSLPIVNLKGQVLFNNW
DSIFSGHGGQFNMHIPIYSFDGRDIMTDPSWPQKVIWHGSSPHGVRLVDNYCEAWRTADTAVTGLASPLSTGKILDQKAYSCANRLIVLC

--------------------------------------------------------------
>20167_20167_2_CTDSP2-COL15A1_CTDSP2_chr12_58240154_ENST00000548823_COL15A1_chr9_101759215_ENST00000375001_length(transcript)=4597nt_BP=333nt
ATGTTGGACCCAAACTGAGGAGCCCGGAGCTGCCGCTGGGGGATCGGGGCCGGGGGCACCCGGGGGAGCCGCTGCCCGGGCCGCCCGCCC
TTTGTACAGGCCGCCTCCCTTCCCGGTCCGGGGAGGAAACGAGAGGGGGGATGTGAACAGCTGTGGAAGTCGGAGTCTCGGGAGCCGGAG
CGGGCCCCCGCCCAGGCCCCCCAGCCCAGCCCAGCCCGCGCGCCCGCCCGTCCTCCCGCCCAGCCAGCCCGGGCCCGCGGGATTGTTAGA
TGGAACACGGCTCCATCATCACCCAGGCGCGGAGGGAAGACGCCCTGGTGCTCACCAAGCAAGCCCAAAGAAGCAAAAGTTGAACCCATA
AACACACCTCCAACTCCATCCTCCCCCTTTGAAGACATGGAACTTTCTGGTGAACCTGTACCCGAGGGGACCCTGGAAACCACCAACATG
AGCATCATCCAGCACAGCAGCCCCAAACAAGGGTCTGGTGAGATCCTGAATGACACACTGGAGGGGGTTCATTCTGTGGATGGTGACCCC
ATTACTGACAGCGGCTCAGGGGCTGGGGCCTTCCTTGACATTGCTGAAGAAAAGAATTTAGCAGCAACAGCAGCGGGGCTGGCCGAGGTG
CCCATCAGCACTGCTGGAGAAGCAGAGGCCAGCAGTGTGCCCACCGGGGGACCAACCCTCTCTATGTCCACGGAGAACCCAGAGGAAGGG
GTCACTCCAGGTCCAGATAATGAAGAGCGTTTAGCAGCAACAGCAGCAGGGGAGGCCGAGGCACTCGCCAGCATGCCTGGGGAAGTGGAG
GCCAGTGGTGTGGCCCCCGGGGAGCTGGACCTCTCCATGTCCGCCCAGAGCCTCGGGGAAGAGGCCACTGTGGGTCCAAGCAGTGAAGAC
AGTTTAACAACAGCTGCAGCTGCAACCGAAGTGTCCCTCAGTACTTTTGAGGATGAGGAAGCCAGTGGGGTCCCCACAGATGGCCTGGCT
CCCCTCACAGCCACCATGGCCCCTGAGCGGGCAGTCACTTCTGGTCCTGGTGATGAAGAAGACTTGGCAGCAGCCACAACAGAGGAGCCC
CTCATCACAGCTGGGGGTGAAGAGTCCGGCAGCCCTCCCCCTGATGGGCCACCGCTGCCCCTGCCCACAGTGGCTCCTGAAAGATGGATC
ACTCCAGCTCAAAGAGAACATGTGGGAATGAAAGGACAGGCTGGGCCCAAAGGAGAAAAGGGTGATGCTGGGGAGGAGCTTCCTGGCCCT
CCTGAACCTTCTGGGCCTGTTGGACCCACGGCAGGAGCAGAAGCAGAGGGCTCTGGCCTAGGCTGGGGCTCGGACGTCGGCTCTGGCTCT
GGTGACCTGGTGGGCAGTGAGCAGCTGCTGAGAGGTCCTCCAGGACCCCCAGGGCCACCTGGCTTACCTGGGATTCCAGGAAAACCAGGA
ACTGATGTTTTCATGGGACCCCCTGGATCTCCTGGAGAGGATGGACCTGCTGGTGAACCTGGGCCCCCGGGCCCTGAGGGACAGCCTGGA
GTTGATGGAGCCACCGGCCTTCCCGGGATGAAAGGGGAGAAGGGAGCAAGAGGGCCTAATGGCTCAGTTGGTGAAAAGGGTGACCCTGGC
AACAGAGGCTTACCTGGACCCCCGGGGAAAAAGGGACAAGCTGGCCCTCCTGGGGTCATGGGACCCCCAGGGCCTCCTGGACCCCCTGGG
CCCCCAGGCCCTGGATGCACAATGGGACTTGGATTCGAGGATACCGAAGGCTCTGGAAGCACCCAGCTATTGAATGAACCCAAACTCTCC
AGACCAACGGCTGCAATTGGTCTCAAAGGAGAGAAAGGAGACCGGGGACCCAAGGGAGAAAGGGGGATGGATGGAGCCAGTATTGTGGGA
CCCCCTGGGCCGAGAGGGCCACCTGGGCACATCAAGGTCTTGTCTAATTCCTTGATCAATATCACCCATGGATTCATGAATTTCTCGGAC
ATTCCTGAGCTGGTGGGGCCTCCGGGGCCGGACGGGTTGCCTGGGCTGCCAGGATTTCCAGGTCCTAGAGGACCAAAAGGTGACACTGGT
TTACCTGGCTTTCCAGGACTAAAAGGAGAACAGGGCGAGAAGGGAGAGCCGGGTGCCATCCTGACAGAGGACATTCCTCTGGAAAGGCTG
ATGGGGAAAAAGGGTGAACCTGGAATGCATGGAGCCCCAGGACCAATGGGGCCCAAAGGACCACCAGGACATAAAGGAGAATTTGGCCTT
CCCGGGCGACCTGGTCGCCCAGGACTGAATGGCCTCAAGGGTACCAAAGGAGATCCAGGGGTCATTATGCAGGGCCCACCTGGCTTACCT
GGCCCTCCAGGCCCCCCTGGGCCACCTGGAGCTGTGATTAACATCAAAGGAGCCATTTTCCCAATACCCGTCCGACCACACTGCAAAATG
CCAGTTGATACTGCTCATCCTGGGAGTCCAGAGCTCATCACTTTTCACGGTGTTAAAGGAGAGAAAGGATCCTGGGGTCTTCCTGGCTCA
AAGGGAGAAAAAGGCGACCAGGGAGCCCAGGGACCACCAGGTCCTCCACTTGATCTAGCTTACCTGAGACACTTTCTGAACAACTTGAAG
GGGGAGAATGGAGACAAGGGGTTCAAAGGTGAAAAAGGAGAAAAAGGAGACATTAATGGCAGCTTCCTTATGTCTGGGCCTCCAGGCCTG
CCCGGAAATCCAGGCCCGGCTGGCCAAAAAGGGGAGACAGTCGTTGGGCCCCAAGGACCCCCAGGTGCTCCTGGTCTGCCTGGGCCACCT
GGCTTTGGAAGACCTGGTGATCCTGGGCCACCGGGGCCCCCGGGGCCACCAGGACCTCCAGCTATCCTGGGAGCAGCTGTGGCCCTTCCA
GGTCCCCCTGGCCCTCCAGGACAGCCAGGGCTTCCCGGATCCAGAAACCTGGTCACAGCATTCAGCAACATGGATGACATGCTGCAGAAA
GCGCATTTGGTTATAGAAGGAACATTCATCTACCTGAGGGACAGCACTGAGTTTTTCATTCGTGTTAGAGATGGCTGGAAAAAATTACAG
CTGGGAGAACTGATCCCCATTCCTGCCGACAGCCCTCCACCCCCTGCGCTTTCCAGCAACCCACATCAGCTTCTGCCTCCACCAAACCCT
ATTTCAAGTGCCAATTATGAGAAGCCTGCTCTGCATTTGGCTGCTCTGAACATGCCATTTTCTGGGGACATTCGAGCTGATTTTCAGTGC
TTCAAGCAGGCCAGAGCTGCAGGACTGTTGTCCACCTACCGAGCATTCTTATCTTCCCATTTGCAAGATCTGTCCACCATTGTGAGGAAA
GCAGAGAGATACAGCCTTCCCATAGTGAACCTCAAGGGCCAAGTACTTTTTAATAATTGGGACTCAATTTTTTCTGGCCACGGAGGTCAG
TTCAATATGCATATTCCAATATACTCCTTTGATGGTCGAGACATAATGACAGATCCTTCTTGGCCCCAGAAAGTCATTTGGCATGGCTCC
AGCCCCCATGGCGTCCGCCTTGTGGATAACTACTGTGAAGCATGGCGAACCGCGGACACAGCGGTCACGGGACTTGCCTCCCCGCTGAGC
ACGGGGAAGATTCTGGACCAGAAAGCATACAGCTGTGCTAATCGGCTAATTGTCCTATGTATCGAAAACAGTTTCATGACAGACGCTAGG
AAGTAATGGCCTTCTGATGATTCTTAAAGAGTTTTCAATTTTTTCTTATGTGAAGAGTTGACACTGAAATCTAAAATGTTTAATTGTTGT
AAATATTACAGTTTTTTTTTTTTACTACATATTCTTTACAACAGCAACCAAAGAAAACATACCTCAATACACTCAAAACTGAAGACATAG
AGGACTCAGATCAAAGACAAAATCTGATCCATATATTGGTGCTAGATTCTGCAGGAAACCCCAGCAGTGTGAACGCATCCCAACATAGGT
TAAGAGCAAGTTGAAAACAAAGGCCATGGCATTCTGCCACTGCATCCTTCAGACAGTTATATCCTCCTTTTAAACCATTGTTGTTGAGTG
TAAGATGTCCTTCATGTTTTCTTATAAAGTCAGTGTTTAGAAATGTTACCCTTTCTAAGTTATATACAGATCAAATGCTTTTTTCTTTCA
CGTACATCCATCATTTGCAACTGCTGTTCGTACACAGAAACAGGACTGCTCAAATGATCCTATTTGTATTTTCTGATGCTATCAGACTCT
AATGTTTTTTTCCCTAAAATATTATTGCCATCATGCTTTAGGAATTTTATATTTTTACACAATCATATTTTAGTATGGTGTCTGTTTATG
TAACTCTGACTTGCTGGAAAAGTTGAAACTCCAAATAATCTGAAACTAGAAAAGAAATAGCACATAATTACTACCTTCCCCTTGGCGGCT
CTCCTCCCCAACCCCCACCCCACAATTTTATGACTTCCATTTGGCAATTGTTGAATTATAACTGCGACTGAAACAAACAGGTTCATAGAG
ATGAATTTTCTGAGAAACATATATCTACATGTTGTATAATTGGATTTTTTTTCCATGTAAGTGAACATAAAAACATCTTTTCCGGGTGCT

>20167_20167_2_CTDSP2-COL15A1_CTDSP2_chr12_58240154_ENST00000548823_COL15A1_chr9_101759215_ENST00000375001_length(amino acids)=1181AA_BP=487
MWKSESREPERAPAQAPQPSPARAPARPPAQPARARGIVRWNTAPSSPRRGGKTPWCSPSKPKEAKVEPINTPPTPSSPFEDMELSGEPV
PEGTLETTNMSIIQHSSPKQGSGEILNDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAATAAGLAEVPISTAGEAEASSVPTGGPTL
SMSTENPEEGVTPGPDNEERLAATAAGEAEALASMPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEE
ASGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEK
GDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEP
GPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGS
TQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFP
GPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPG
VIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLA
YLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGPP
AILGAAVALPGPPGPPGQPGLPGSRNLVTAFSNMDDMLQKAHLVIEGTFIYLRDSTEFFIRVRDGWKKLQLGELIPIPADSPPPPALSSN
PHQLLPPPNPISSANYEKPALHLAALNMPFSGDIRADFQCFKQARAAGLLSTYRAFLSSHLQDLSTIVRKAERYSLPIVNLKGQVLFNNW
DSIFSGHGGQFNMHIPIYSFDGRDIMTDPSWPQKVIWHGSSPHGVRLVDNYCEAWRTADTAVTGLASPLSTGKILDQKAYSCANRLIVLC

--------------------------------------------------------------
>20167_20167_3_CTDSP2-COL15A1_CTDSP2_chr12_58240155_ENST00000398073_COL15A1_chr9_101759216_ENST00000375001_length(transcript)=4632nt_BP=368nt
CCATTTCCTCCTCTTGTTTTCGCTCCGGATTCTCCATGTTGGACCCAAACTGAGGAGCCCGGAGCTGCCGCTGGGGGATCGGGGCCGGGG
GCACCCGGGGGAGCCGCTGCCCGGGCCGCCCGCCCTTTGTACAGGCCGCCTCCCTTCCCGGTCCGGGGAGGAAACGAGAGGGGGGATGTG
AACAGCTGTGGAAGTCGGAGTCTCGGGAGCCGGAGCGGGCCCCCGCCCAGGCCCCCCAGCCCAGCCCAGCCCGCGCGCCCGCCCGTCCTC
CCGCCCAGCCAGCCCGGGCCCGCGGGATTGTTAGATGGAACACGGCTCCATCATCACCCAGGCGCGGAGGGAAGACGCCCTGGTGCTCAC
CAAGCAAGCCCAAAGAAGCAAAAGTTGAACCCATAAACACACCTCCAACTCCATCCTCCCCCTTTGAAGACATGGAACTTTCTGGTGAAC
CTGTACCCGAGGGGACCCTGGAAACCACCAACATGAGCATCATCCAGCACAGCAGCCCCAAACAAGGGTCTGGTGAGATCCTGAATGACA
CACTGGAGGGGGTTCATTCTGTGGATGGTGACCCCATTACTGACAGCGGCTCAGGGGCTGGGGCCTTCCTTGACATTGCTGAAGAAAAGA
ATTTAGCAGCAACAGCAGCGGGGCTGGCCGAGGTGCCCATCAGCACTGCTGGAGAAGCAGAGGCCAGCAGTGTGCCCACCGGGGGACCAA
CCCTCTCTATGTCCACGGAGAACCCAGAGGAAGGGGTCACTCCAGGTCCAGATAATGAAGAGCGTTTAGCAGCAACAGCAGCAGGGGAGG
CCGAGGCACTCGCCAGCATGCCTGGGGAAGTGGAGGCCAGTGGTGTGGCCCCCGGGGAGCTGGACCTCTCCATGTCCGCCCAGAGCCTCG
GGGAAGAGGCCACTGTGGGTCCAAGCAGTGAAGACAGTTTAACAACAGCTGCAGCTGCAACCGAAGTGTCCCTCAGTACTTTTGAGGATG
AGGAAGCCAGTGGGGTCCCCACAGATGGCCTGGCTCCCCTCACAGCCACCATGGCCCCTGAGCGGGCAGTCACTTCTGGTCCTGGTGATG
AAGAAGACTTGGCAGCAGCCACAACAGAGGAGCCCCTCATCACAGCTGGGGGTGAAGAGTCCGGCAGCCCTCCCCCTGATGGGCCACCGC
TGCCCCTGCCCACAGTGGCTCCTGAAAGATGGATCACTCCAGCTCAAAGAGAACATGTGGGAATGAAAGGACAGGCTGGGCCCAAAGGAG
AAAAGGGTGATGCTGGGGAGGAGCTTCCTGGCCCTCCTGAACCTTCTGGGCCTGTTGGACCCACGGCAGGAGCAGAAGCAGAGGGCTCTG
GCCTAGGCTGGGGCTCGGACGTCGGCTCTGGCTCTGGTGACCTGGTGGGCAGTGAGCAGCTGCTGAGAGGTCCTCCAGGACCCCCAGGGC
CACCTGGCTTACCTGGGATTCCAGGAAAACCAGGAACTGATGTTTTCATGGGACCCCCTGGATCTCCTGGAGAGGATGGACCTGCTGGTG
AACCTGGGCCCCCGGGCCCTGAGGGACAGCCTGGAGTTGATGGAGCCACCGGCCTTCCCGGGATGAAAGGGGAGAAGGGAGCAAGAGGGC
CTAATGGCTCAGTTGGTGAAAAGGGTGACCCTGGCAACAGAGGCTTACCTGGACCCCCGGGGAAAAAGGGACAAGCTGGCCCTCCTGGGG
TCATGGGACCCCCAGGGCCTCCTGGACCCCCTGGGCCCCCAGGCCCTGGATGCACAATGGGACTTGGATTCGAGGATACCGAAGGCTCTG
GAAGCACCCAGCTATTGAATGAACCCAAACTCTCCAGACCAACGGCTGCAATTGGTCTCAAAGGAGAGAAAGGAGACCGGGGACCCAAGG
GAGAAAGGGGGATGGATGGAGCCAGTATTGTGGGACCCCCTGGGCCGAGAGGGCCACCTGGGCACATCAAGGTCTTGTCTAATTCCTTGA
TCAATATCACCCATGGATTCATGAATTTCTCGGACATTCCTGAGCTGGTGGGGCCTCCGGGGCCGGACGGGTTGCCTGGGCTGCCAGGAT
TTCCAGGTCCTAGAGGACCAAAAGGTGACACTGGTTTACCTGGCTTTCCAGGACTAAAAGGAGAACAGGGCGAGAAGGGAGAGCCGGGTG
CCATCCTGACAGAGGACATTCCTCTGGAAAGGCTGATGGGGAAAAAGGGTGAACCTGGAATGCATGGAGCCCCAGGACCAATGGGGCCCA
AAGGACCACCAGGACATAAAGGAGAATTTGGCCTTCCCGGGCGACCTGGTCGCCCAGGACTGAATGGCCTCAAGGGTACCAAAGGAGATC
CAGGGGTCATTATGCAGGGCCCACCTGGCTTACCTGGCCCTCCAGGCCCCCCTGGGCCACCTGGAGCTGTGATTAACATCAAAGGAGCCA
TTTTCCCAATACCCGTCCGACCACACTGCAAAATGCCAGTTGATACTGCTCATCCTGGGAGTCCAGAGCTCATCACTTTTCACGGTGTTA
AAGGAGAGAAAGGATCCTGGGGTCTTCCTGGCTCAAAGGGAGAAAAAGGCGACCAGGGAGCCCAGGGACCACCAGGTCCTCCACTTGATC
TAGCTTACCTGAGACACTTTCTGAACAACTTGAAGGGGGAGAATGGAGACAAGGGGTTCAAAGGTGAAAAAGGAGAAAAAGGAGACATTA
ATGGCAGCTTCCTTATGTCTGGGCCTCCAGGCCTGCCCGGAAATCCAGGCCCGGCTGGCCAAAAAGGGGAGACAGTCGTTGGGCCCCAAG
GACCCCCAGGTGCTCCTGGTCTGCCTGGGCCACCTGGCTTTGGAAGACCTGGTGATCCTGGGCCACCGGGGCCCCCGGGGCCACCAGGAC
CTCCAGCTATCCTGGGAGCAGCTGTGGCCCTTCCAGGTCCCCCTGGCCCTCCAGGACAGCCAGGGCTTCCCGGATCCAGAAACCTGGTCA
CAGCATTCAGCAACATGGATGACATGCTGCAGAAAGCGCATTTGGTTATAGAAGGAACATTCATCTACCTGAGGGACAGCACTGAGTTTT
TCATTCGTGTTAGAGATGGCTGGAAAAAATTACAGCTGGGAGAACTGATCCCCATTCCTGCCGACAGCCCTCCACCCCCTGCGCTTTCCA
GCAACCCACATCAGCTTCTGCCTCCACCAAACCCTATTTCAAGTGCCAATTATGAGAAGCCTGCTCTGCATTTGGCTGCTCTGAACATGC
CATTTTCTGGGGACATTCGAGCTGATTTTCAGTGCTTCAAGCAGGCCAGAGCTGCAGGACTGTTGTCCACCTACCGAGCATTCTTATCTT
CCCATTTGCAAGATCTGTCCACCATTGTGAGGAAAGCAGAGAGATACAGCCTTCCCATAGTGAACCTCAAGGGCCAAGTACTTTTTAATA
ATTGGGACTCAATTTTTTCTGGCCACGGAGGTCAGTTCAATATGCATATTCCAATATACTCCTTTGATGGTCGAGACATAATGACAGATC
CTTCTTGGCCCCAGAAAGTCATTTGGCATGGCTCCAGCCCCCATGGCGTCCGCCTTGTGGATAACTACTGTGAAGCATGGCGAACCGCGG
ACACAGCGGTCACGGGACTTGCCTCCCCGCTGAGCACGGGGAAGATTCTGGACCAGAAAGCATACAGCTGTGCTAATCGGCTAATTGTCC
TATGTATCGAAAACAGTTTCATGACAGACGCTAGGAAGTAATGGCCTTCTGATGATTCTTAAAGAGTTTTCAATTTTTTCTTATGTGAAG
AGTTGACACTGAAATCTAAAATGTTTAATTGTTGTAAATATTACAGTTTTTTTTTTTTACTACATATTCTTTACAACAGCAACCAAAGAA
AACATACCTCAATACACTCAAAACTGAAGACATAGAGGACTCAGATCAAAGACAAAATCTGATCCATATATTGGTGCTAGATTCTGCAGG
AAACCCCAGCAGTGTGAACGCATCCCAACATAGGTTAAGAGCAAGTTGAAAACAAAGGCCATGGCATTCTGCCACTGCATCCTTCAGACA
GTTATATCCTCCTTTTAAACCATTGTTGTTGAGTGTAAGATGTCCTTCATGTTTTCTTATAAAGTCAGTGTTTAGAAATGTTACCCTTTC
TAAGTTATATACAGATCAAATGCTTTTTTCTTTCACGTACATCCATCATTTGCAACTGCTGTTCGTACACAGAAACAGGACTGCTCAAAT
GATCCTATTTGTATTTTCTGATGCTATCAGACTCTAATGTTTTTTTCCCTAAAATATTATTGCCATCATGCTTTAGGAATTTTATATTTT
TACACAATCATATTTTAGTATGGTGTCTGTTTATGTAACTCTGACTTGCTGGAAAAGTTGAAACTCCAAATAATCTGAAACTAGAAAAGA
AATAGCACATAATTACTACCTTCCCCTTGGCGGCTCTCCTCCCCAACCCCCACCCCACAATTTTATGACTTCCATTTGGCAATTGTTGAA
TTATAACTGCGACTGAAACAAACAGGTTCATAGAGATGAATTTTCTGAGAAACATATATCTACATGTTGTATAATTGGATTTTTTTTCCA

>20167_20167_3_CTDSP2-COL15A1_CTDSP2_chr12_58240155_ENST00000398073_COL15A1_chr9_101759216_ENST00000375001_length(amino acids)=1181AA_BP=487
MWKSESREPERAPAQAPQPSPARAPARPPAQPARARGIVRWNTAPSSPRRGGKTPWCSPSKPKEAKVEPINTPPTPSSPFEDMELSGEPV
PEGTLETTNMSIIQHSSPKQGSGEILNDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAATAAGLAEVPISTAGEAEASSVPTGGPTL
SMSTENPEEGVTPGPDNEERLAATAAGEAEALASMPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEE
ASGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEK
GDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEP
GPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGS
TQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFP
GPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPG
VIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLA
YLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGPP
AILGAAVALPGPPGPPGQPGLPGSRNLVTAFSNMDDMLQKAHLVIEGTFIYLRDSTEFFIRVRDGWKKLQLGELIPIPADSPPPPALSSN
PHQLLPPPNPISSANYEKPALHLAALNMPFSGDIRADFQCFKQARAAGLLSTYRAFLSSHLQDLSTIVRKAERYSLPIVNLKGQVLFNNW
DSIFSGHGGQFNMHIPIYSFDGRDIMTDPSWPQKVIWHGSSPHGVRLVDNYCEAWRTADTAVTGLASPLSTGKILDQKAYSCANRLIVLC

--------------------------------------------------------------
>20167_20167_4_CTDSP2-COL15A1_CTDSP2_chr12_58240155_ENST00000548823_COL15A1_chr9_101759216_ENST00000375001_length(transcript)=4597nt_BP=333nt
ATGTTGGACCCAAACTGAGGAGCCCGGAGCTGCCGCTGGGGGATCGGGGCCGGGGGCACCCGGGGGAGCCGCTGCCCGGGCCGCCCGCCC
TTTGTACAGGCCGCCTCCCTTCCCGGTCCGGGGAGGAAACGAGAGGGGGGATGTGAACAGCTGTGGAAGTCGGAGTCTCGGGAGCCGGAG
CGGGCCCCCGCCCAGGCCCCCCAGCCCAGCCCAGCCCGCGCGCCCGCCCGTCCTCCCGCCCAGCCAGCCCGGGCCCGCGGGATTGTTAGA
TGGAACACGGCTCCATCATCACCCAGGCGCGGAGGGAAGACGCCCTGGTGCTCACCAAGCAAGCCCAAAGAAGCAAAAGTTGAACCCATA
AACACACCTCCAACTCCATCCTCCCCCTTTGAAGACATGGAACTTTCTGGTGAACCTGTACCCGAGGGGACCCTGGAAACCACCAACATG
AGCATCATCCAGCACAGCAGCCCCAAACAAGGGTCTGGTGAGATCCTGAATGACACACTGGAGGGGGTTCATTCTGTGGATGGTGACCCC
ATTACTGACAGCGGCTCAGGGGCTGGGGCCTTCCTTGACATTGCTGAAGAAAAGAATTTAGCAGCAACAGCAGCGGGGCTGGCCGAGGTG
CCCATCAGCACTGCTGGAGAAGCAGAGGCCAGCAGTGTGCCCACCGGGGGACCAACCCTCTCTATGTCCACGGAGAACCCAGAGGAAGGG
GTCACTCCAGGTCCAGATAATGAAGAGCGTTTAGCAGCAACAGCAGCAGGGGAGGCCGAGGCACTCGCCAGCATGCCTGGGGAAGTGGAG
GCCAGTGGTGTGGCCCCCGGGGAGCTGGACCTCTCCATGTCCGCCCAGAGCCTCGGGGAAGAGGCCACTGTGGGTCCAAGCAGTGAAGAC
AGTTTAACAACAGCTGCAGCTGCAACCGAAGTGTCCCTCAGTACTTTTGAGGATGAGGAAGCCAGTGGGGTCCCCACAGATGGCCTGGCT
CCCCTCACAGCCACCATGGCCCCTGAGCGGGCAGTCACTTCTGGTCCTGGTGATGAAGAAGACTTGGCAGCAGCCACAACAGAGGAGCCC
CTCATCACAGCTGGGGGTGAAGAGTCCGGCAGCCCTCCCCCTGATGGGCCACCGCTGCCCCTGCCCACAGTGGCTCCTGAAAGATGGATC
ACTCCAGCTCAAAGAGAACATGTGGGAATGAAAGGACAGGCTGGGCCCAAAGGAGAAAAGGGTGATGCTGGGGAGGAGCTTCCTGGCCCT
CCTGAACCTTCTGGGCCTGTTGGACCCACGGCAGGAGCAGAAGCAGAGGGCTCTGGCCTAGGCTGGGGCTCGGACGTCGGCTCTGGCTCT
GGTGACCTGGTGGGCAGTGAGCAGCTGCTGAGAGGTCCTCCAGGACCCCCAGGGCCACCTGGCTTACCTGGGATTCCAGGAAAACCAGGA
ACTGATGTTTTCATGGGACCCCCTGGATCTCCTGGAGAGGATGGACCTGCTGGTGAACCTGGGCCCCCGGGCCCTGAGGGACAGCCTGGA
GTTGATGGAGCCACCGGCCTTCCCGGGATGAAAGGGGAGAAGGGAGCAAGAGGGCCTAATGGCTCAGTTGGTGAAAAGGGTGACCCTGGC
AACAGAGGCTTACCTGGACCCCCGGGGAAAAAGGGACAAGCTGGCCCTCCTGGGGTCATGGGACCCCCAGGGCCTCCTGGACCCCCTGGG
CCCCCAGGCCCTGGATGCACAATGGGACTTGGATTCGAGGATACCGAAGGCTCTGGAAGCACCCAGCTATTGAATGAACCCAAACTCTCC
AGACCAACGGCTGCAATTGGTCTCAAAGGAGAGAAAGGAGACCGGGGACCCAAGGGAGAAAGGGGGATGGATGGAGCCAGTATTGTGGGA
CCCCCTGGGCCGAGAGGGCCACCTGGGCACATCAAGGTCTTGTCTAATTCCTTGATCAATATCACCCATGGATTCATGAATTTCTCGGAC
ATTCCTGAGCTGGTGGGGCCTCCGGGGCCGGACGGGTTGCCTGGGCTGCCAGGATTTCCAGGTCCTAGAGGACCAAAAGGTGACACTGGT
TTACCTGGCTTTCCAGGACTAAAAGGAGAACAGGGCGAGAAGGGAGAGCCGGGTGCCATCCTGACAGAGGACATTCCTCTGGAAAGGCTG
ATGGGGAAAAAGGGTGAACCTGGAATGCATGGAGCCCCAGGACCAATGGGGCCCAAAGGACCACCAGGACATAAAGGAGAATTTGGCCTT
CCCGGGCGACCTGGTCGCCCAGGACTGAATGGCCTCAAGGGTACCAAAGGAGATCCAGGGGTCATTATGCAGGGCCCACCTGGCTTACCT
GGCCCTCCAGGCCCCCCTGGGCCACCTGGAGCTGTGATTAACATCAAAGGAGCCATTTTCCCAATACCCGTCCGACCACACTGCAAAATG
CCAGTTGATACTGCTCATCCTGGGAGTCCAGAGCTCATCACTTTTCACGGTGTTAAAGGAGAGAAAGGATCCTGGGGTCTTCCTGGCTCA
AAGGGAGAAAAAGGCGACCAGGGAGCCCAGGGACCACCAGGTCCTCCACTTGATCTAGCTTACCTGAGACACTTTCTGAACAACTTGAAG
GGGGAGAATGGAGACAAGGGGTTCAAAGGTGAAAAAGGAGAAAAAGGAGACATTAATGGCAGCTTCCTTATGTCTGGGCCTCCAGGCCTG
CCCGGAAATCCAGGCCCGGCTGGCCAAAAAGGGGAGACAGTCGTTGGGCCCCAAGGACCCCCAGGTGCTCCTGGTCTGCCTGGGCCACCT
GGCTTTGGAAGACCTGGTGATCCTGGGCCACCGGGGCCCCCGGGGCCACCAGGACCTCCAGCTATCCTGGGAGCAGCTGTGGCCCTTCCA
GGTCCCCCTGGCCCTCCAGGACAGCCAGGGCTTCCCGGATCCAGAAACCTGGTCACAGCATTCAGCAACATGGATGACATGCTGCAGAAA
GCGCATTTGGTTATAGAAGGAACATTCATCTACCTGAGGGACAGCACTGAGTTTTTCATTCGTGTTAGAGATGGCTGGAAAAAATTACAG
CTGGGAGAACTGATCCCCATTCCTGCCGACAGCCCTCCACCCCCTGCGCTTTCCAGCAACCCACATCAGCTTCTGCCTCCACCAAACCCT
ATTTCAAGTGCCAATTATGAGAAGCCTGCTCTGCATTTGGCTGCTCTGAACATGCCATTTTCTGGGGACATTCGAGCTGATTTTCAGTGC
TTCAAGCAGGCCAGAGCTGCAGGACTGTTGTCCACCTACCGAGCATTCTTATCTTCCCATTTGCAAGATCTGTCCACCATTGTGAGGAAA
GCAGAGAGATACAGCCTTCCCATAGTGAACCTCAAGGGCCAAGTACTTTTTAATAATTGGGACTCAATTTTTTCTGGCCACGGAGGTCAG
TTCAATATGCATATTCCAATATACTCCTTTGATGGTCGAGACATAATGACAGATCCTTCTTGGCCCCAGAAAGTCATTTGGCATGGCTCC
AGCCCCCATGGCGTCCGCCTTGTGGATAACTACTGTGAAGCATGGCGAACCGCGGACACAGCGGTCACGGGACTTGCCTCCCCGCTGAGC
ACGGGGAAGATTCTGGACCAGAAAGCATACAGCTGTGCTAATCGGCTAATTGTCCTATGTATCGAAAACAGTTTCATGACAGACGCTAGG
AAGTAATGGCCTTCTGATGATTCTTAAAGAGTTTTCAATTTTTTCTTATGTGAAGAGTTGACACTGAAATCTAAAATGTTTAATTGTTGT
AAATATTACAGTTTTTTTTTTTTACTACATATTCTTTACAACAGCAACCAAAGAAAACATACCTCAATACACTCAAAACTGAAGACATAG
AGGACTCAGATCAAAGACAAAATCTGATCCATATATTGGTGCTAGATTCTGCAGGAAACCCCAGCAGTGTGAACGCATCCCAACATAGGT
TAAGAGCAAGTTGAAAACAAAGGCCATGGCATTCTGCCACTGCATCCTTCAGACAGTTATATCCTCCTTTTAAACCATTGTTGTTGAGTG
TAAGATGTCCTTCATGTTTTCTTATAAAGTCAGTGTTTAGAAATGTTACCCTTTCTAAGTTATATACAGATCAAATGCTTTTTTCTTTCA
CGTACATCCATCATTTGCAACTGCTGTTCGTACACAGAAACAGGACTGCTCAAATGATCCTATTTGTATTTTCTGATGCTATCAGACTCT
AATGTTTTTTTCCCTAAAATATTATTGCCATCATGCTTTAGGAATTTTATATTTTTACACAATCATATTTTAGTATGGTGTCTGTTTATG
TAACTCTGACTTGCTGGAAAAGTTGAAACTCCAAATAATCTGAAACTAGAAAAGAAATAGCACATAATTACTACCTTCCCCTTGGCGGCT
CTCCTCCCCAACCCCCACCCCACAATTTTATGACTTCCATTTGGCAATTGTTGAATTATAACTGCGACTGAAACAAACAGGTTCATAGAG
ATGAATTTTCTGAGAAACATATATCTACATGTTGTATAATTGGATTTTTTTTCCATGTAAGTGAACATAAAAACATCTTTTCCGGGTGCT

>20167_20167_4_CTDSP2-COL15A1_CTDSP2_chr12_58240155_ENST00000548823_COL15A1_chr9_101759216_ENST00000375001_length(amino acids)=1181AA_BP=487
MWKSESREPERAPAQAPQPSPARAPARPPAQPARARGIVRWNTAPSSPRRGGKTPWCSPSKPKEAKVEPINTPPTPSSPFEDMELSGEPV
PEGTLETTNMSIIQHSSPKQGSGEILNDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAATAAGLAEVPISTAGEAEASSVPTGGPTL
SMSTENPEEGVTPGPDNEERLAATAAGEAEALASMPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEE
ASGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEK
GDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEP
GPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGS
TQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFP
GPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPG
VIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLA
YLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGPP
AILGAAVALPGPPGPPGQPGLPGSRNLVTAFSNMDDMLQKAHLVIEGTFIYLRDSTEFFIRVRDGWKKLQLGELIPIPADSPPPPALSSN
PHQLLPPPNPISSANYEKPALHLAALNMPFSGDIRADFQCFKQARAAGLLSTYRAFLSSHLQDLSTIVRKAERYSLPIVNLKGQVLFNNW
DSIFSGHGGQFNMHIPIYSFDGRDIMTDPSWPQKVIWHGSSPHGVRLVDNYCEAWRTADTAVTGLASPLSTGKILDQKAYSCANRLIVLC

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Fusion Gene PPI Analysis for CTDSP2-COL15A1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CTDSP2-COL15A1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CTDSP2-COL15A1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource