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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CTNNA1-KDM3B (FusionGDB2 ID:20259)

Fusion Gene Summary for CTNNA1-KDM3B

check button Fusion gene summary
Fusion gene informationFusion gene name: CTNNA1-KDM3B
Fusion gene ID: 20259
HgeneTgene
Gene symbol

CTNNA1

KDM3B

Gene ID

1495

51780

Gene namecatenin alpha 1lysine demethylase 3B
SynonymsCAP102|MDPT25qNCA|C5orf7|JMJD1B|NET22
Cytomap

5q31.2

5q31.2

Type of geneprotein-codingprotein-coding
Descriptioncatenin alpha-1alpha-E-catenincatenin (cadherin-associated protein), alpha 1, 102kDaepididymis secretory sperm binding proteinrenal carcinoma antigen NY-REN-13lysine-specific demethylase 3BjmjC domain-containing histone demethylation protein 2Bjumonji domain containing 1Bjumonji domain-containing protein 1Blysine (K)-specific demethylase 3Bnuclear protein 5qNCA
Modification date2020031320200313
UniProtAcc.

Q7LBC6

Ensembl transtripts involved in fusion geneENST00000302763, ENST00000355078, 
ENST00000518825, ENST00000520400, 
ENST00000540387, 		ENST00000394866, 
ENST00000508386, ENST00000542866, 
ENST00000314358, 
Fusion gene scores* DoF score25 X 19 X 12=570011 X 11 X 5=605
# samples 3413
** MAII scorelog2(34/5700*10)=-4.06735526780176
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/605*10)=-2.2184235191335
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CTNNA1 [Title/Abstract] AND KDM3B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCTNNA1(138163407)-KDM3B(137708362), # samples:1
CTNNA1(138163407)-KDM3B(137708363), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCTNNA1

GO:0071681

cellular response to indole-3-methanol

10868478


check buttonFusion gene breakpoints across CTNNA1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across KDM3B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-09-0366-01ACTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
ChimerDB4OVTCGA-09-0366CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+


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Fusion Gene ORF analysis for CTNNA1-KDM3B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000302763ENST00000394866CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
5CDS-intronENST00000302763ENST00000394866CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+
5CDS-intronENST00000302763ENST00000508386CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
5CDS-intronENST00000302763ENST00000508386CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+
5CDS-intronENST00000302763ENST00000542866CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
5CDS-intronENST00000302763ENST00000542866CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+
5CDS-intronENST00000355078ENST00000394866CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
5CDS-intronENST00000355078ENST00000394866CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+
5CDS-intronENST00000355078ENST00000508386CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
5CDS-intronENST00000355078ENST00000508386CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+
5CDS-intronENST00000355078ENST00000542866CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
5CDS-intronENST00000355078ENST00000542866CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+
5CDS-intronENST00000518825ENST00000394866CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
5CDS-intronENST00000518825ENST00000394866CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+
5CDS-intronENST00000518825ENST00000508386CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
5CDS-intronENST00000518825ENST00000508386CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+
5CDS-intronENST00000518825ENST00000542866CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
5CDS-intronENST00000518825ENST00000542866CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+
In-frameENST00000302763ENST00000314358CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
In-frameENST00000302763ENST00000314358CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+
In-frameENST00000355078ENST00000314358CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
In-frameENST00000355078ENST00000314358CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+
In-frameENST00000518825ENST00000314358CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
In-frameENST00000518825ENST00000314358CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+
intron-3CDSENST00000520400ENST00000314358CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
intron-3CDSENST00000520400ENST00000314358CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+
intron-3CDSENST00000540387ENST00000314358CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
intron-3CDSENST00000540387ENST00000314358CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+
intron-intronENST00000520400ENST00000394866CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
intron-intronENST00000520400ENST00000394866CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+
intron-intronENST00000520400ENST00000508386CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
intron-intronENST00000520400ENST00000508386CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+
intron-intronENST00000520400ENST00000542866CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
intron-intronENST00000520400ENST00000542866CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+
intron-intronENST00000540387ENST00000394866CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
intron-intronENST00000540387ENST00000394866CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+
intron-intronENST00000540387ENST00000508386CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
intron-intronENST00000540387ENST00000508386CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+
intron-intronENST00000540387ENST00000542866CTNNA1chr5

138163407

+KDM3Bchr5

137708363

+
intron-intronENST00000540387ENST00000542866CTNNA1chr5

138163407

+KDM3Bchr5

137708362

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000355078CTNNA1chr5138163407+ENST00000314358KDM3Bchr5137708362+737995820260511949
ENST00000302763CTNNA1chr5138163407+ENST00000314358KDM3Bchr5137708362+757311529062452051
ENST00000518825CTNNA1chr5138163407+ENST00000314358KDM3Bchr5137708362+74851064261572051
ENST00000355078CTNNA1chr5138163407+ENST00000314358KDM3Bchr5137708363+737995820260511949
ENST00000302763CTNNA1chr5138163407+ENST00000314358KDM3Bchr5137708363+757311529062452051
ENST00000518825CTNNA1chr5138163407+ENST00000314358KDM3Bchr5137708363+74851064261572051

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000355078ENST00000314358CTNNA1chr5138163407+KDM3Bchr5137708362+0.0007946910.9992053
ENST00000302763ENST00000314358CTNNA1chr5138163407+KDM3Bchr5137708362+0.0006507990.9993492
ENST00000518825ENST00000314358CTNNA1chr5138163407+KDM3Bchr5137708362+0.0005562840.9994437
ENST00000355078ENST00000314358CTNNA1chr5138163407+KDM3Bchr5137708363+0.0007946910.9992053
ENST00000302763ENST00000314358CTNNA1chr5138163407+KDM3Bchr5137708363+0.0006507990.9993492
ENST00000518825ENST00000314358CTNNA1chr5138163407+KDM3Bchr5137708363+0.0005562840.9994437

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Fusion Genomic Features for CTNNA1-KDM3B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CTNNA1chr5138163407+KDM3Bchr5137708362+9.39E-111
CTNNA1chr5138163407+KDM3Bchr5137708362+9.39E-111
CTNNA1chr5138163407+KDM3Bchr5137708362+9.39E-111
CTNNA1chr5138163407+KDM3Bchr5137708362+9.39E-111

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CTNNA1-KDM3B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:138163407/chr5:137708362)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.KDM3B

Q7LBC6

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity. {ECO:0000269|PubMed:16603237}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCTNNA1chr5:138163407chr5:137708362ENST00000302763+7182_228354907.0RegionNote=Involved in homodimerization
HgeneCTNNA1chr5:138163407chr5:137708363ENST00000302763+7182_228354907.0RegionNote=Involved in homodimerization
TgeneKDM3Bchr5:138163407chr5:137708362ENST00000314358024647_744641762.0Compositional biasNote=Ser-rich
TgeneKDM3Bchr5:138163407chr5:137708362ENST00000394866019647_74401418.0Compositional biasNote=Ser-rich
TgeneKDM3Bchr5:138163407chr5:137708363ENST00000314358024647_744641762.0Compositional biasNote=Ser-rich
TgeneKDM3Bchr5:138163407chr5:137708363ENST00000394866019647_74401418.0Compositional biasNote=Ser-rich
TgeneKDM3Bchr5:138163407chr5:137708362ENST000003143580241498_1721641762.0DomainJmjC
TgeneKDM3Bchr5:138163407chr5:137708362ENST000003948660191498_172101418.0DomainJmjC
TgeneKDM3Bchr5:138163407chr5:137708363ENST000003143580241498_1721641762.0DomainJmjC
TgeneKDM3Bchr5:138163407chr5:137708363ENST000003948660191498_172101418.0DomainJmjC
TgeneKDM3Bchr5:138163407chr5:137708362ENST000003143580241293_1297641762.0MotifNote=LXXLL motif
TgeneKDM3Bchr5:138163407chr5:137708362ENST000003948660191293_129701418.0MotifNote=LXXLL motif
TgeneKDM3Bchr5:138163407chr5:137708363ENST000003143580241293_1297641762.0MotifNote=LXXLL motif
TgeneKDM3Bchr5:138163407chr5:137708363ENST000003948660191293_129701418.0MotifNote=LXXLL motif
TgeneKDM3Bchr5:138163407chr5:137708362ENST000003143580241031_1056641762.0Zinc fingerC6-type
TgeneKDM3Bchr5:138163407chr5:137708362ENST000003948660191031_105601418.0Zinc fingerC6-type
TgeneKDM3Bchr5:138163407chr5:137708363ENST000003143580241031_1056641762.0Zinc fingerC6-type
TgeneKDM3Bchr5:138163407chr5:137708363ENST000003948660191031_105601418.0Zinc fingerC6-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCTNNA1chr5:138163407chr5:137708362ENST00000540387+1122_2280537.0RegionNote=Involved in homodimerization
HgeneCTNNA1chr5:138163407chr5:137708363ENST00000540387+1122_2280537.0RegionNote=Involved in homodimerization


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Fusion Gene Sequence for CTNNA1-KDM3B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>20259_20259_1_CTNNA1-KDM3B_CTNNA1_chr5_138163407_ENST00000302763_KDM3B_chr5_137708362_ENST00000314358_length(transcript)=7573nt_BP=1152nt
TCCTCCTCCTAGCCGGACTGGAGGGAGACAAAGCAGCGCCCGTCTGCTTCGGGCCTCTGGAATTTAGCGCTCGCCCAGCTAGCCGCAGAA
ATGACTGCTGTCCATGCAGGCAACATAAACTTCAAGTGGGATCCTAAAAGTCTAGAGATCAGGACTCTGGCAGTTGAGAGACTGTTGGAG
CCTCTTGTTACACAGGTTACAACCCTTGTAAACACCAATAGTAAAGGGCCCTCTAATAAGAAGAGAGGTCGTTCTAAGAAGGCCCATGTT
TTGGCTGCATCTGTTGAACAAGCAACTGAGAATTTCTTGGAGAAGGGGGATAAAATTGCGAAGGAGAGCCAGTTTCTCAAGGAGGAGCTT
GTGGCTGCTGTAGAAGATGTTCGAAAACAAGGTGATTTGATGAAGGCTGCTGCAGGAGAGTTCGCAGATGATCCCTGCTCTTCTGTGAAG
CGAGGCAACATGGTTCGGGCAGCTCGAGCTTTGCTCTCTGCTGTTACCCGGTTGCTGATTTTGGCTGACATGGCAGATGTCTACAAATTA
CTTGTTCAGCTGAAAGTTGTGGAAGATGGTATCTTGAAGTTGAGGAATGCTGGCAATGAACAAGACTTAGGAATCCAGTATAAAGCCCTA
AAACCTGAAGTGGATAAGCTGAACATTATGGCAGCCAAAAGACAACAGGAATTGAAAGATGTTGGCCATCGTGATCAGATGGCTGCAGCT
AGAGGAATCCTGCAGAAGAACGTTCCGATCCTCTATACTGCATCCCAGGCATGCCTACAGCACCCTGATGTCGCAGCCTATAAGGCCAAC
AGGGACCTGATATACAAGCAGCTGCAGCAGGCGGTCACAGGCATTTCCAATGCAGCCCAGGCCACTGCCTCAGACGATGCCTCACAGCAC
CAGGGTGGAGGAGGAGGAGAACTGGCATATGCACTCAATAACTTTGACAAACAAATCATTGTGGACCCCTTGAGCTTCAGCGAGGAGCGC
TTTAGGCCTTCCCTGGAGGAGCGTCTGGAAAGCATCATTAGTGGGGCTGCCTTGATGGCCGACTCGTCCTGCACGCGTGATGACCGTCGT
GAGCGAATTGTGGCAGAGTGTAATGCTGTCCGCCAGGCCCTGCAGGACCTGCTTTCGGAGTACATGGGCAATATCTTTGTAGAATTTGAT
GGCTGTAACTGGAAGCAACACTCCTGGGTAAAAGTTCATGCTGAGGAAGTTATCGTGCTTCTGCTGGAAGGGTCTCTTGTATGGGCGCCC
CGTGAGGACCCAGTCCTTCTCCAGGGCATTCGAGTCTCCATTGCACAATGGCCAGCCCTGACTTTTACTCCCCTTGTAGATAAACTGGGT
TTGGGTTCTGTGGTTCCAGTGGAATATCTTCTGGATCGAGAGCTTCGGTTCCTGTCAGATGCCAATGGGTTGCATCTGTTTCAGATGGGA
ACAGATAGCCAAAACCAGATTCTTTTGGAACATGCTGCACTGAGAGAAACAGTTAATGCTTTGATCAGTGACCAAAAGCTACAAGAGATA
TTCAGCCGAGGTCCCTACAGTGTTCAAGGTCACAGGGTCAAAATATATCAGCCAGAGGGGGAAGAAGGGTGGCTCTATGGTGTTGTGAGC
CATCAGGACTCCATCACTCGTCTTATGGAGGTGTCTGTAACTGAGAGTGGTGAGATCAAGTCGGTAGATCCCAGACTAATCCATGTGATG
CTGATGGATAATTCAGCGCCTCAAAGCGAGGGGGGTACGTTAAAAGCAGTAAAATCTTCCAAAGGAAAGAAGAAGAGAGAAAGCATAGAG
GGGAAAGATGGCCGGAGGAGGAAAAGTGCTTCGGACTCTGGGTGTGACCCTGCATCAAAGAAATTAAAAGGAGACAGGGGTGAAGTAGAC
AGTAATGGGAGCGATGGAGGTGAGGCAAGCCGAGGGCCCTGGAAAGGAGGGAATGCCAGTGGAGAGCCAGGGCTGGATCAGAGAGCCAAG
CAGCCACCGTCTACATTTGTCCCCCAGATAAACCGCAACATTCGCTTTGCCACTTACACCAAAGAAAACGGCAGGACTCTGGTGGTGCAG
GATGAGCCTGTAGGTGGGGACACACCTGCATCTTTCACTCCATATTCTACAGCCACAGGTCAGACACCTTTGGCCCCAGAGGTGGGTGGA
GCCGAAAACAAAGAGGCAGGAAAAACACTGGAACAAGTTGGCCAGGGCATAGTGGCTTCCGCAGCTGTGGTCACTACCGCCAGCTCCACC
CCAAACACAGTGAGGATCTCAGACACTGGCCTTGCAGCAGGGACTGTGCCAGAAAAACAGAAAGGCAGCCGGTCGCAGGCCTCGGGAGAG
AATTCAAGAAATTCTATTCTGGCCTCTTCTGGATTTGGAGCACCTCTCCCTAGTTCATCGCAACCTTTGACTTTTGGAAGTGGAAGGAGC
CAGTCCAATGGTGTTCTAGCCACAGAGAACAAACCTTTGGGCTTCTCTTTTGGCTGTAGCTCTGCACAAGAGGCACAGAAAGACACTGAT
CTCTCCAAAAACTTGTTTTTTCAATGCATGTCCCAAACTTTACCTACCAGTAACTACTTCACTACTGTTTCAGAGAGTTTGGCTGATGAT
TCTTCTAGTCGGGACTCATTCAAACAAAGCCTTGAGAGCCTGAGCTCAGGCCTGTGTAAAGGCAGATCCGTTCTTGGAACAGACACTAAG
CCAGGCTCTAAGGCTGGCAGCTCTGTGGACCGGAAAGTGCCTGCAGAGTCCATGCCCACCCTCACTCCAGCCTTCCCACGGAGCCTCCTA
AATGCCCGTACCCCAGAGAATCATGAAAATCTATTTTTACAGCCCCCCAAATTGTCCCGAGAAGAGCCTTCTAATCCTTTCCTGGCATTT
GTGGAGAAAGTTGAACACAGCCCTTTCAGTAGTTTTGCATCTCAGGCATCAGGTAGCTCCTCTTCTGCTACCACTGTCACCTCCAAGGTG
GCACCCAGCTGGCCCGAGTCTCACTCCTCTGCAGATTCGGCATCTTTAGCAAAGAAGAAACCCCTCTTCATTACAACTGACTCCTCCAAG
CTAGTATCTGGTGTTCTGGGCTCAGCTCTTACCAGTGGGGGCCCAAGCCTCTCTGCCATGGGGAATGGCCGCTCCAGCTCGCCCACCAGC
AGCCTCACTCAGCCCATTGAGATGCCAACTCTCTCCTCTAGCCCCACAGAGGAGAGGCCAACTGTGGGGCCTGGGCAGCAGGACAATCCC
CTCCTCAAAACCTTTAGTAACGTCTTTGGCAGGCACTCAGGCGGCTTTCTGTCCTCCCCGGCAGATTTTTCACAGGAGAACAAAGCTCCT
TTTGAAGCTGTGAAAAGGTTCTCACTGGATGAACGAAGCTTGGCTTGCAGACAAGACTCGGACTCCAGCACCAACAGTGACCTGTCAGAT
TTGAGTGACTCTGAGGAGCAGCTGCAGGCTAAGACAGGCCTGAAGGGAATTCCAGAGCACCTGATGGGGAAGCTGGGCCCCAATGGGGAG
CGCAGTGCTGAGCTGTTGCTGGGCAAAAGCAAAGGGAAGCAGGCCCCCAAGGGCCGGCCTCGGACTGCCCCCCTGAAAGTTGGCCAGTCA
GTGCTGAAAGATGTAAGCAAAGTGAAGAAGCTGAAGCAATCTGGAGAGCCCTTCCTGCAGGATGGGTCATGCATCAATGTGGCACCTCAT
CTGCACAAGTGTCGTGAATGCCGCCTGGAGCGGTACCGGAAGTTTAAGGAACAGGAGCAAGATGATTCTACTGTAGCCTGCCGTTTCTTT
CACTTCCGGAGGTTGATCTTCACTCGAAAAGGGGTACTCCGTGTGGAGGGGTTTTTAAGCCCCCAGCAAAGTGACCCTGATGCCATGAAC
CTGTGGATTCCCTCTTCCTCCCTAGCAGAAGGGATAGATCTAGAGACCTCAAAATACATCCTGGCCAATGTTGGGGACCAGTTCTGCCAG
CTCGTAATGTCTGAGAAGGAGGCCATGATGATGGTGGAGCCACACCAGAAAGTGGCATGGAAGCGAGCTGTGCGTGGTGTACGGGAGATG
TGTGATGTGTGTGAAACAACTCTCTTCAACATCCACTGGGTTTGTCGCAAATGTGGATTTGGGGTCTGCCTTGACTGTTACCGGCTCAGG
AAAAGCCGGCCACGCAGTGAGACAGAAGAGATGGGTGATGAAGAAGTTTTCTCCTGGTTGAAGTGTGCAAAGGGACAGTCCCACGAACCA
GAGAATCTCATGCCCACACAAATTATTCCTGGCACAGCTCTTTACAATATTGGAGACATGGTACATGCTGCCCGGGGCAAGTGGGGAATT
AAAGCAAACTGCCCTTGTATCAGTCGACAGAACAAATCTGTATTGAGACCTGCCGTCACCAATGGGATGTCACAGCTTCCTAGCATAAAC
CCTAGTGCCTCTTCTGGAAACGAAACTACCTTCTCTGGTGGAGGAGGACCGGCACCAGTAACAACTCCAGAGCCGGACCATGTTCCCAAA
GCCGACAGCACTGACATCAGATCTGAAGAGCCTCTGAAAACAGACAGTTCGGCATCAAATAGCAATAGTGAACTGAAAGCCATCAGGCCT
CCTTGCCCTGACACGGCCCCACCCTCCTCCGCCCTGCACTGGTTGGCAGATTTAGCAACTCAGAAGGCTAAAGAAGAAACAAAAGAAGCA
GGGTCCCTGAGGTCGGTGCTCAATAAAGAGTCTCATTCACCCTTTGGGCTGGACTCGTTCAACTCCACTGCAAAGGTCTCTCCGCTGACT
CCAAAGCTTTTTAACAGTCTGTTGCTGGGTCCCACTGCCTCCAACAACAAAACCGAAGGGTCTAGCCTTCGAGACCTCCTTCACTCCGGG
CCGGGAAAACTTCCTCAAACCCCCTTGGACACAGGCATACCCTTTCCCCCGGTCTTCTCTACATCCTCAGCAGGAGTGAAGAGCAAGGCC
AGCCTACCCAACTTTCTTGACCACATCATTGCCTCAGTGGTAGAAAATAAGAAAACCTCAGATGCTTCAAAGCGGGCCTGCAACTTGACT
GATACCCAGAAGGAAGTGAAGGAGATGGTGATGGGGTTAAATGTGCTAGATCCCCATACTTCTCACTCCTGGCTTTGTGATGGGAGGCTT
CTGTGTCTCCATGACCCCAGCAACAAAAACAATTGGAAGATCTTCCGGGAGTGTTGGAAGCAAGGTCAGCCAGTGCTGGTTTCGGGGGTA
CATAAAAAGCTCAAGTCTGAGCTCTGGAAGCCAGAAGCCTTTAGCCAGGAATTTGGAGACCAGGATGTAGACTTGGTGAACTGCAGGAAC
TGTGCTATAATTTCCGATGTGAAAGTTCGGGATTTCTGGGATGGTTTCGAGATCATATGCAAACGACTACGGTCAGAAGATGGGCAGCCA
ATGGTGCTCAAACTCAAGGACTGGCCTCCTGGGGAAGATTTTCGAGACATGATGCCAACCAGGTTTGAAGATCTGATGGAGAACCTTCCT
CTGCCAGAATATACCAAACGAGATGGCAGGCTCAATCTGGCCTCTAGGCTACCTAGCTACTTTGTAAGGCCTGATCTGGGCCCCAAGATG
TACAACGCCTATGGGTTGATAACAGCAGAAGATAGAAGAGTTGGTACAACAAATCTTCACTTAGATGTGTCTGATGCTGTTAATGTGATG
GTGTATGTTGGGATTCCCATCGGGGAGGGTGCTCATGATGAAGAGGTACTCAAGACAATTGACGAGGGAGATGCCGATGAGGTGACGAAG
CAGAGGATTCATGATGGAAAAGAGAAGCCAGGTGCTTTATGGCACATCTATGCAGCCAAGGATGCAGAGAAGATCCGGGAGCTGCTCCGA
AAGGTTGGAGAAGAACAAGGCCAAGAGAACCCCCCTGATCATGACCCAATTCATGACCAAAGTTGGTACCTGGACCAGACCCTCCGTAAG
CGACTCTATGAGGAGTATGGCGTGCAAGGCTGGGCTATTGTGCAGTTCCTAGGTGATGCTGTTTTCATACCTGCTGGAGCCCCACACCAG
GTTCACAATCTATACAGTTGCATAAAAGTAGCAGAAGACTTTGTATCTCCAGAACATGTAAAGCACTGTTTCCGCCTGACTCAGGAATTC
AGGCATCTCTCTAACACTCATACAAATCATGAGGATAAACTGCAGGTGAAGAACATCATTTACCATGCAGTGAAAGATGCGGTTGGCACC
CTCAAGGCTCATGAATCCAAACTGGCAAGGTCCTAGGCATGGAGAAACTCCAAGCTCCTCTGTGAAGCAGGTCTTTCACTCACAACACTT
AACAGGGAACGGCAGGGCTCTTTGCTGGAGCAGAGGCCCTTCACCCAGAGCCAGTGTGGTCAGTATTCCAAACTCTCCAGCCACTCTCTT
CTACGCTGCCTCAACACTGAAGGTTGACACAGGAAAGTCGTACTGTTCACACACACAGTTTGAGACTCCAAGCCAAGAGTGCCACATCCC
TATCCTGTGGCCTTTTGGAAATCCAAATTGCCTGAACATGGCGGGGCTTTCCTGCACATTCTCCTGATTTGAGATTCACGGGCACACCTT
TCTTTTCTTTTCCTCTTGTGCCTAGTTAAGTGGAAATGTGTTTGGAGATAGGGGAAATCACATAACTGGTACAAGTATGGGGTAATTGCT
TAAACATGCCTGGTGGAAGTCTGATAGCGTCTCTGCACGTGACCTCTGACAAAGCCCATCCCAGGAGACGGGGTGAAGCTATTCCCCACA
CTCTCCTGTGAACACTGGAGTCTTGCAAGACCCAGGGAGAACCCACTGCTTTTCCCAGGAGGCTCCAGGATTAGGAAATGTGTGTATTTA
GTGAAAAATAGGTTTGTAGTGAAATAGTTACTATTTCATGAAAGTAGATATTTTTAGAATTTTTGAAATACCACAGTTGTTTTCCTGGAT
TATAAGGAAAGGCACATTACATTTAGTCTTCCTTTCGATATAAAACTCTTTGAAGAAATATGATTTTTAGAAATCAGCTACCCATTATAG
CACAAAATCAGCCAAAGCAGAATTTTTAAAAATTGGCTTTTTTAGGATTCTTTTTCTCCCCCTCCCATCTTAGTCTTACCTTGAGGGAAC
AGTCATATGAGAAGGAACTTTGTCACATCTAAGCTGTGGTGTGTTCCCCATGTGTGTGTACAACACTGGTGACTCCAGGAACCATTTTCA
CCTATTACCAGTGTTCCCTGGGGACTCCTCTTAATGTTTCCAAATGGGAAGGACAGTTGATTTCCAACATGAGGTTTTTTGTTTTTTATC
CAGAAATATTTTCAGCAAAACTTTCCAACTGAGTGGAGTCTGATTAAGGATTTATTTGAAAATGGTGGGATTCATTGGCCCATAGGTACA
TTGGAAAATGTATATCTCTCCAGCTGTACTGTAGTGCCCTGCAGGCTGTTTATATGTTCACAGTTACTTTTTTTTTTTTTTTTAAATAAA
AGTCATTTAATGTAGAATACTTTTAATTTCACTTTCTGTATTTTAATTTTGTTGAAGGGCTGATTGGGATTTCCATGTTCTTATTAAAAA

>20259_20259_1_CTNNA1-KDM3B_CTNNA1_chr5_138163407_ENST00000302763_KDM3B_chr5_137708362_ENST00000314358_length(amino acids)=2051AA_BP=354
MTAVHAGNINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQATENFLEKGDKIAKESQFLKEEL
VAAVEDVRKQGDLMKAAAGEFADDPCSSVKRGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKAL
KPEVDKLNIMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQATASDDASQH
QGGGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNIFVEFD
GCNWKQHSWVKVHAEEVIVLLLEGSLVWAPREDPVLLQGIRVSIAQWPALTFTPLVDKLGLGSVVPVEYLLDRELRFLSDANGLHLFQMG
TDSQNQILLEHAALRETVNALISDQKLQEIFSRGPYSVQGHRVKIYQPEGEEGWLYGVVSHQDSITRLMEVSVTESGEIKSVDPRLIHVM
LMDNSAPQSEGGTLKAVKSSKGKKKRESIEGKDGRRRKSASDSGCDPASKKLKGDRGEVDSNGSDGGEASRGPWKGGNASGEPGLDQRAK
QPPSTFVPQINRNIRFATYTKENGRTLVVQDEPVGGDTPASFTPYSTATGQTPLAPEVGGAENKEAGKTLEQVGQGIVASAAVVTTASST
PNTVRISDTGLAAGTVPEKQKGSRSQASGENSRNSILASSGFGAPLPSSSQPLTFGSGRSQSNGVLATENKPLGFSFGCSSAQEAQKDTD
LSKNLFFQCMSQTLPTSNYFTTVSESLADDSSSRDSFKQSLESLSSGLCKGRSVLGTDTKPGSKAGSSVDRKVPAESMPTLTPAFPRSLL
NARTPENHENLFLQPPKLSREEPSNPFLAFVEKVEHSPFSSFASQASGSSSSATTVTSKVAPSWPESHSSADSASLAKKKPLFITTDSSK
LVSGVLGSALTSGGPSLSAMGNGRSSSPTSSLTQPIEMPTLSSSPTEERPTVGPGQQDNPLLKTFSNVFGRHSGGFLSSPADFSQENKAP
FEAVKRFSLDERSLACRQDSDSSTNSDLSDLSDSEEQLQAKTGLKGIPEHLMGKLGPNGERSAELLLGKSKGKQAPKGRPRTAPLKVGQS
VLKDVSKVKKLKQSGEPFLQDGSCINVAPHLHKCRECRLERYRKFKEQEQDDSTVACRFFHFRRLIFTRKGVLRVEGFLSPQQSDPDAMN
LWIPSSSLAEGIDLETSKYILANVGDQFCQLVMSEKEAMMMVEPHQKVAWKRAVRGVREMCDVCETTLFNIHWVCRKCGFGVCLDCYRLR
KSRPRSETEEMGDEEVFSWLKCAKGQSHEPENLMPTQIIPGTALYNIGDMVHAARGKWGIKANCPCISRQNKSVLRPAVTNGMSQLPSIN
PSASSGNETTFSGGGGPAPVTTPEPDHVPKADSTDIRSEEPLKTDSSASNSNSELKAIRPPCPDTAPPSSALHWLADLATQKAKEETKEA
GSLRSVLNKESHSPFGLDSFNSTAKVSPLTPKLFNSLLLGPTASNNKTEGSSLRDLLHSGPGKLPQTPLDTGIPFPPVFSTSSAGVKSKA
SLPNFLDHIIASVVENKKTSDASKRACNLTDTQKEVKEMVMGLNVLDPHTSHSWLCDGRLLCLHDPSNKNNWKIFRECWKQGQPVLVSGV
HKKLKSELWKPEAFSQEFGDQDVDLVNCRNCAIISDVKVRDFWDGFEIICKRLRSEDGQPMVLKLKDWPPGEDFRDMMPTRFEDLMENLP
LPEYTKRDGRLNLASRLPSYFVRPDLGPKMYNAYGLITAEDRRVGTTNLHLDVSDAVNVMVYVGIPIGEGAHDEEVLKTIDEGDADEVTK
QRIHDGKEKPGALWHIYAAKDAEKIRELLRKVGEEQGQENPPDHDPIHDQSWYLDQTLRKRLYEEYGVQGWAIVQFLGDAVFIPAGAPHQ

--------------------------------------------------------------
>20259_20259_2_CTNNA1-KDM3B_CTNNA1_chr5_138163407_ENST00000302763_KDM3B_chr5_137708363_ENST00000314358_length(transcript)=7573nt_BP=1152nt
TCCTCCTCCTAGCCGGACTGGAGGGAGACAAAGCAGCGCCCGTCTGCTTCGGGCCTCTGGAATTTAGCGCTCGCCCAGCTAGCCGCAGAA
ATGACTGCTGTCCATGCAGGCAACATAAACTTCAAGTGGGATCCTAAAAGTCTAGAGATCAGGACTCTGGCAGTTGAGAGACTGTTGGAG
CCTCTTGTTACACAGGTTACAACCCTTGTAAACACCAATAGTAAAGGGCCCTCTAATAAGAAGAGAGGTCGTTCTAAGAAGGCCCATGTT
TTGGCTGCATCTGTTGAACAAGCAACTGAGAATTTCTTGGAGAAGGGGGATAAAATTGCGAAGGAGAGCCAGTTTCTCAAGGAGGAGCTT
GTGGCTGCTGTAGAAGATGTTCGAAAACAAGGTGATTTGATGAAGGCTGCTGCAGGAGAGTTCGCAGATGATCCCTGCTCTTCTGTGAAG
CGAGGCAACATGGTTCGGGCAGCTCGAGCTTTGCTCTCTGCTGTTACCCGGTTGCTGATTTTGGCTGACATGGCAGATGTCTACAAATTA
CTTGTTCAGCTGAAAGTTGTGGAAGATGGTATCTTGAAGTTGAGGAATGCTGGCAATGAACAAGACTTAGGAATCCAGTATAAAGCCCTA
AAACCTGAAGTGGATAAGCTGAACATTATGGCAGCCAAAAGACAACAGGAATTGAAAGATGTTGGCCATCGTGATCAGATGGCTGCAGCT
AGAGGAATCCTGCAGAAGAACGTTCCGATCCTCTATACTGCATCCCAGGCATGCCTACAGCACCCTGATGTCGCAGCCTATAAGGCCAAC
AGGGACCTGATATACAAGCAGCTGCAGCAGGCGGTCACAGGCATTTCCAATGCAGCCCAGGCCACTGCCTCAGACGATGCCTCACAGCAC
CAGGGTGGAGGAGGAGGAGAACTGGCATATGCACTCAATAACTTTGACAAACAAATCATTGTGGACCCCTTGAGCTTCAGCGAGGAGCGC
TTTAGGCCTTCCCTGGAGGAGCGTCTGGAAAGCATCATTAGTGGGGCTGCCTTGATGGCCGACTCGTCCTGCACGCGTGATGACCGTCGT
GAGCGAATTGTGGCAGAGTGTAATGCTGTCCGCCAGGCCCTGCAGGACCTGCTTTCGGAGTACATGGGCAATATCTTTGTAGAATTTGAT
GGCTGTAACTGGAAGCAACACTCCTGGGTAAAAGTTCATGCTGAGGAAGTTATCGTGCTTCTGCTGGAAGGGTCTCTTGTATGGGCGCCC
CGTGAGGACCCAGTCCTTCTCCAGGGCATTCGAGTCTCCATTGCACAATGGCCAGCCCTGACTTTTACTCCCCTTGTAGATAAACTGGGT
TTGGGTTCTGTGGTTCCAGTGGAATATCTTCTGGATCGAGAGCTTCGGTTCCTGTCAGATGCCAATGGGTTGCATCTGTTTCAGATGGGA
ACAGATAGCCAAAACCAGATTCTTTTGGAACATGCTGCACTGAGAGAAACAGTTAATGCTTTGATCAGTGACCAAAAGCTACAAGAGATA
TTCAGCCGAGGTCCCTACAGTGTTCAAGGTCACAGGGTCAAAATATATCAGCCAGAGGGGGAAGAAGGGTGGCTCTATGGTGTTGTGAGC
CATCAGGACTCCATCACTCGTCTTATGGAGGTGTCTGTAACTGAGAGTGGTGAGATCAAGTCGGTAGATCCCAGACTAATCCATGTGATG
CTGATGGATAATTCAGCGCCTCAAAGCGAGGGGGGTACGTTAAAAGCAGTAAAATCTTCCAAAGGAAAGAAGAAGAGAGAAAGCATAGAG
GGGAAAGATGGCCGGAGGAGGAAAAGTGCTTCGGACTCTGGGTGTGACCCTGCATCAAAGAAATTAAAAGGAGACAGGGGTGAAGTAGAC
AGTAATGGGAGCGATGGAGGTGAGGCAAGCCGAGGGCCCTGGAAAGGAGGGAATGCCAGTGGAGAGCCAGGGCTGGATCAGAGAGCCAAG
CAGCCACCGTCTACATTTGTCCCCCAGATAAACCGCAACATTCGCTTTGCCACTTACACCAAAGAAAACGGCAGGACTCTGGTGGTGCAG
GATGAGCCTGTAGGTGGGGACACACCTGCATCTTTCACTCCATATTCTACAGCCACAGGTCAGACACCTTTGGCCCCAGAGGTGGGTGGA
GCCGAAAACAAAGAGGCAGGAAAAACACTGGAACAAGTTGGCCAGGGCATAGTGGCTTCCGCAGCTGTGGTCACTACCGCCAGCTCCACC
CCAAACACAGTGAGGATCTCAGACACTGGCCTTGCAGCAGGGACTGTGCCAGAAAAACAGAAAGGCAGCCGGTCGCAGGCCTCGGGAGAG
AATTCAAGAAATTCTATTCTGGCCTCTTCTGGATTTGGAGCACCTCTCCCTAGTTCATCGCAACCTTTGACTTTTGGAAGTGGAAGGAGC
CAGTCCAATGGTGTTCTAGCCACAGAGAACAAACCTTTGGGCTTCTCTTTTGGCTGTAGCTCTGCACAAGAGGCACAGAAAGACACTGAT
CTCTCCAAAAACTTGTTTTTTCAATGCATGTCCCAAACTTTACCTACCAGTAACTACTTCACTACTGTTTCAGAGAGTTTGGCTGATGAT
TCTTCTAGTCGGGACTCATTCAAACAAAGCCTTGAGAGCCTGAGCTCAGGCCTGTGTAAAGGCAGATCCGTTCTTGGAACAGACACTAAG
CCAGGCTCTAAGGCTGGCAGCTCTGTGGACCGGAAAGTGCCTGCAGAGTCCATGCCCACCCTCACTCCAGCCTTCCCACGGAGCCTCCTA
AATGCCCGTACCCCAGAGAATCATGAAAATCTATTTTTACAGCCCCCCAAATTGTCCCGAGAAGAGCCTTCTAATCCTTTCCTGGCATTT
GTGGAGAAAGTTGAACACAGCCCTTTCAGTAGTTTTGCATCTCAGGCATCAGGTAGCTCCTCTTCTGCTACCACTGTCACCTCCAAGGTG
GCACCCAGCTGGCCCGAGTCTCACTCCTCTGCAGATTCGGCATCTTTAGCAAAGAAGAAACCCCTCTTCATTACAACTGACTCCTCCAAG
CTAGTATCTGGTGTTCTGGGCTCAGCTCTTACCAGTGGGGGCCCAAGCCTCTCTGCCATGGGGAATGGCCGCTCCAGCTCGCCCACCAGC
AGCCTCACTCAGCCCATTGAGATGCCAACTCTCTCCTCTAGCCCCACAGAGGAGAGGCCAACTGTGGGGCCTGGGCAGCAGGACAATCCC
CTCCTCAAAACCTTTAGTAACGTCTTTGGCAGGCACTCAGGCGGCTTTCTGTCCTCCCCGGCAGATTTTTCACAGGAGAACAAAGCTCCT
TTTGAAGCTGTGAAAAGGTTCTCACTGGATGAACGAAGCTTGGCTTGCAGACAAGACTCGGACTCCAGCACCAACAGTGACCTGTCAGAT
TTGAGTGACTCTGAGGAGCAGCTGCAGGCTAAGACAGGCCTGAAGGGAATTCCAGAGCACCTGATGGGGAAGCTGGGCCCCAATGGGGAG
CGCAGTGCTGAGCTGTTGCTGGGCAAAAGCAAAGGGAAGCAGGCCCCCAAGGGCCGGCCTCGGACTGCCCCCCTGAAAGTTGGCCAGTCA
GTGCTGAAAGATGTAAGCAAAGTGAAGAAGCTGAAGCAATCTGGAGAGCCCTTCCTGCAGGATGGGTCATGCATCAATGTGGCACCTCAT
CTGCACAAGTGTCGTGAATGCCGCCTGGAGCGGTACCGGAAGTTTAAGGAACAGGAGCAAGATGATTCTACTGTAGCCTGCCGTTTCTTT
CACTTCCGGAGGTTGATCTTCACTCGAAAAGGGGTACTCCGTGTGGAGGGGTTTTTAAGCCCCCAGCAAAGTGACCCTGATGCCATGAAC
CTGTGGATTCCCTCTTCCTCCCTAGCAGAAGGGATAGATCTAGAGACCTCAAAATACATCCTGGCCAATGTTGGGGACCAGTTCTGCCAG
CTCGTAATGTCTGAGAAGGAGGCCATGATGATGGTGGAGCCACACCAGAAAGTGGCATGGAAGCGAGCTGTGCGTGGTGTACGGGAGATG
TGTGATGTGTGTGAAACAACTCTCTTCAACATCCACTGGGTTTGTCGCAAATGTGGATTTGGGGTCTGCCTTGACTGTTACCGGCTCAGG
AAAAGCCGGCCACGCAGTGAGACAGAAGAGATGGGTGATGAAGAAGTTTTCTCCTGGTTGAAGTGTGCAAAGGGACAGTCCCACGAACCA
GAGAATCTCATGCCCACACAAATTATTCCTGGCACAGCTCTTTACAATATTGGAGACATGGTACATGCTGCCCGGGGCAAGTGGGGAATT
AAAGCAAACTGCCCTTGTATCAGTCGACAGAACAAATCTGTATTGAGACCTGCCGTCACCAATGGGATGTCACAGCTTCCTAGCATAAAC
CCTAGTGCCTCTTCTGGAAACGAAACTACCTTCTCTGGTGGAGGAGGACCGGCACCAGTAACAACTCCAGAGCCGGACCATGTTCCCAAA
GCCGACAGCACTGACATCAGATCTGAAGAGCCTCTGAAAACAGACAGTTCGGCATCAAATAGCAATAGTGAACTGAAAGCCATCAGGCCT
CCTTGCCCTGACACGGCCCCACCCTCCTCCGCCCTGCACTGGTTGGCAGATTTAGCAACTCAGAAGGCTAAAGAAGAAACAAAAGAAGCA
GGGTCCCTGAGGTCGGTGCTCAATAAAGAGTCTCATTCACCCTTTGGGCTGGACTCGTTCAACTCCACTGCAAAGGTCTCTCCGCTGACT
CCAAAGCTTTTTAACAGTCTGTTGCTGGGTCCCACTGCCTCCAACAACAAAACCGAAGGGTCTAGCCTTCGAGACCTCCTTCACTCCGGG
CCGGGAAAACTTCCTCAAACCCCCTTGGACACAGGCATACCCTTTCCCCCGGTCTTCTCTACATCCTCAGCAGGAGTGAAGAGCAAGGCC
AGCCTACCCAACTTTCTTGACCACATCATTGCCTCAGTGGTAGAAAATAAGAAAACCTCAGATGCTTCAAAGCGGGCCTGCAACTTGACT
GATACCCAGAAGGAAGTGAAGGAGATGGTGATGGGGTTAAATGTGCTAGATCCCCATACTTCTCACTCCTGGCTTTGTGATGGGAGGCTT
CTGTGTCTCCATGACCCCAGCAACAAAAACAATTGGAAGATCTTCCGGGAGTGTTGGAAGCAAGGTCAGCCAGTGCTGGTTTCGGGGGTA
CATAAAAAGCTCAAGTCTGAGCTCTGGAAGCCAGAAGCCTTTAGCCAGGAATTTGGAGACCAGGATGTAGACTTGGTGAACTGCAGGAAC
TGTGCTATAATTTCCGATGTGAAAGTTCGGGATTTCTGGGATGGTTTCGAGATCATATGCAAACGACTACGGTCAGAAGATGGGCAGCCA
ATGGTGCTCAAACTCAAGGACTGGCCTCCTGGGGAAGATTTTCGAGACATGATGCCAACCAGGTTTGAAGATCTGATGGAGAACCTTCCT
CTGCCAGAATATACCAAACGAGATGGCAGGCTCAATCTGGCCTCTAGGCTACCTAGCTACTTTGTAAGGCCTGATCTGGGCCCCAAGATG
TACAACGCCTATGGGTTGATAACAGCAGAAGATAGAAGAGTTGGTACAACAAATCTTCACTTAGATGTGTCTGATGCTGTTAATGTGATG
GTGTATGTTGGGATTCCCATCGGGGAGGGTGCTCATGATGAAGAGGTACTCAAGACAATTGACGAGGGAGATGCCGATGAGGTGACGAAG
CAGAGGATTCATGATGGAAAAGAGAAGCCAGGTGCTTTATGGCACATCTATGCAGCCAAGGATGCAGAGAAGATCCGGGAGCTGCTCCGA
AAGGTTGGAGAAGAACAAGGCCAAGAGAACCCCCCTGATCATGACCCAATTCATGACCAAAGTTGGTACCTGGACCAGACCCTCCGTAAG
CGACTCTATGAGGAGTATGGCGTGCAAGGCTGGGCTATTGTGCAGTTCCTAGGTGATGCTGTTTTCATACCTGCTGGAGCCCCACACCAG
GTTCACAATCTATACAGTTGCATAAAAGTAGCAGAAGACTTTGTATCTCCAGAACATGTAAAGCACTGTTTCCGCCTGACTCAGGAATTC
AGGCATCTCTCTAACACTCATACAAATCATGAGGATAAACTGCAGGTGAAGAACATCATTTACCATGCAGTGAAAGATGCGGTTGGCACC
CTCAAGGCTCATGAATCCAAACTGGCAAGGTCCTAGGCATGGAGAAACTCCAAGCTCCTCTGTGAAGCAGGTCTTTCACTCACAACACTT
AACAGGGAACGGCAGGGCTCTTTGCTGGAGCAGAGGCCCTTCACCCAGAGCCAGTGTGGTCAGTATTCCAAACTCTCCAGCCACTCTCTT
CTACGCTGCCTCAACACTGAAGGTTGACACAGGAAAGTCGTACTGTTCACACACACAGTTTGAGACTCCAAGCCAAGAGTGCCACATCCC
TATCCTGTGGCCTTTTGGAAATCCAAATTGCCTGAACATGGCGGGGCTTTCCTGCACATTCTCCTGATTTGAGATTCACGGGCACACCTT
TCTTTTCTTTTCCTCTTGTGCCTAGTTAAGTGGAAATGTGTTTGGAGATAGGGGAAATCACATAACTGGTACAAGTATGGGGTAATTGCT
TAAACATGCCTGGTGGAAGTCTGATAGCGTCTCTGCACGTGACCTCTGACAAAGCCCATCCCAGGAGACGGGGTGAAGCTATTCCCCACA
CTCTCCTGTGAACACTGGAGTCTTGCAAGACCCAGGGAGAACCCACTGCTTTTCCCAGGAGGCTCCAGGATTAGGAAATGTGTGTATTTA
GTGAAAAATAGGTTTGTAGTGAAATAGTTACTATTTCATGAAAGTAGATATTTTTAGAATTTTTGAAATACCACAGTTGTTTTCCTGGAT
TATAAGGAAAGGCACATTACATTTAGTCTTCCTTTCGATATAAAACTCTTTGAAGAAATATGATTTTTAGAAATCAGCTACCCATTATAG
CACAAAATCAGCCAAAGCAGAATTTTTAAAAATTGGCTTTTTTAGGATTCTTTTTCTCCCCCTCCCATCTTAGTCTTACCTTGAGGGAAC
AGTCATATGAGAAGGAACTTTGTCACATCTAAGCTGTGGTGTGTTCCCCATGTGTGTGTACAACACTGGTGACTCCAGGAACCATTTTCA
CCTATTACCAGTGTTCCCTGGGGACTCCTCTTAATGTTTCCAAATGGGAAGGACAGTTGATTTCCAACATGAGGTTTTTTGTTTTTTATC
CAGAAATATTTTCAGCAAAACTTTCCAACTGAGTGGAGTCTGATTAAGGATTTATTTGAAAATGGTGGGATTCATTGGCCCATAGGTACA
TTGGAAAATGTATATCTCTCCAGCTGTACTGTAGTGCCCTGCAGGCTGTTTATATGTTCACAGTTACTTTTTTTTTTTTTTTTAAATAAA
AGTCATTTAATGTAGAATACTTTTAATTTCACTTTCTGTATTTTAATTTTGTTGAAGGGCTGATTGGGATTTCCATGTTCTTATTAAAAA

>20259_20259_2_CTNNA1-KDM3B_CTNNA1_chr5_138163407_ENST00000302763_KDM3B_chr5_137708363_ENST00000314358_length(amino acids)=2051AA_BP=354
MTAVHAGNINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQATENFLEKGDKIAKESQFLKEEL
VAAVEDVRKQGDLMKAAAGEFADDPCSSVKRGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKAL
KPEVDKLNIMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQATASDDASQH
QGGGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNIFVEFD
GCNWKQHSWVKVHAEEVIVLLLEGSLVWAPREDPVLLQGIRVSIAQWPALTFTPLVDKLGLGSVVPVEYLLDRELRFLSDANGLHLFQMG
TDSQNQILLEHAALRETVNALISDQKLQEIFSRGPYSVQGHRVKIYQPEGEEGWLYGVVSHQDSITRLMEVSVTESGEIKSVDPRLIHVM
LMDNSAPQSEGGTLKAVKSSKGKKKRESIEGKDGRRRKSASDSGCDPASKKLKGDRGEVDSNGSDGGEASRGPWKGGNASGEPGLDQRAK
QPPSTFVPQINRNIRFATYTKENGRTLVVQDEPVGGDTPASFTPYSTATGQTPLAPEVGGAENKEAGKTLEQVGQGIVASAAVVTTASST
PNTVRISDTGLAAGTVPEKQKGSRSQASGENSRNSILASSGFGAPLPSSSQPLTFGSGRSQSNGVLATENKPLGFSFGCSSAQEAQKDTD
LSKNLFFQCMSQTLPTSNYFTTVSESLADDSSSRDSFKQSLESLSSGLCKGRSVLGTDTKPGSKAGSSVDRKVPAESMPTLTPAFPRSLL
NARTPENHENLFLQPPKLSREEPSNPFLAFVEKVEHSPFSSFASQASGSSSSATTVTSKVAPSWPESHSSADSASLAKKKPLFITTDSSK
LVSGVLGSALTSGGPSLSAMGNGRSSSPTSSLTQPIEMPTLSSSPTEERPTVGPGQQDNPLLKTFSNVFGRHSGGFLSSPADFSQENKAP
FEAVKRFSLDERSLACRQDSDSSTNSDLSDLSDSEEQLQAKTGLKGIPEHLMGKLGPNGERSAELLLGKSKGKQAPKGRPRTAPLKVGQS
VLKDVSKVKKLKQSGEPFLQDGSCINVAPHLHKCRECRLERYRKFKEQEQDDSTVACRFFHFRRLIFTRKGVLRVEGFLSPQQSDPDAMN
LWIPSSSLAEGIDLETSKYILANVGDQFCQLVMSEKEAMMMVEPHQKVAWKRAVRGVREMCDVCETTLFNIHWVCRKCGFGVCLDCYRLR
KSRPRSETEEMGDEEVFSWLKCAKGQSHEPENLMPTQIIPGTALYNIGDMVHAARGKWGIKANCPCISRQNKSVLRPAVTNGMSQLPSIN
PSASSGNETTFSGGGGPAPVTTPEPDHVPKADSTDIRSEEPLKTDSSASNSNSELKAIRPPCPDTAPPSSALHWLADLATQKAKEETKEA
GSLRSVLNKESHSPFGLDSFNSTAKVSPLTPKLFNSLLLGPTASNNKTEGSSLRDLLHSGPGKLPQTPLDTGIPFPPVFSTSSAGVKSKA
SLPNFLDHIIASVVENKKTSDASKRACNLTDTQKEVKEMVMGLNVLDPHTSHSWLCDGRLLCLHDPSNKNNWKIFRECWKQGQPVLVSGV
HKKLKSELWKPEAFSQEFGDQDVDLVNCRNCAIISDVKVRDFWDGFEIICKRLRSEDGQPMVLKLKDWPPGEDFRDMMPTRFEDLMENLP
LPEYTKRDGRLNLASRLPSYFVRPDLGPKMYNAYGLITAEDRRVGTTNLHLDVSDAVNVMVYVGIPIGEGAHDEEVLKTIDEGDADEVTK
QRIHDGKEKPGALWHIYAAKDAEKIRELLRKVGEEQGQENPPDHDPIHDQSWYLDQTLRKRLYEEYGVQGWAIVQFLGDAVFIPAGAPHQ

--------------------------------------------------------------
>20259_20259_3_CTNNA1-KDM3B_CTNNA1_chr5_138163407_ENST00000355078_KDM3B_chr5_137708362_ENST00000314358_length(transcript)=7379nt_BP=958nt
TTTCCTCCTCCTAGCCGGACTGGAGGGAGACAAAGCAGCGCCCGTCTGCTTCGGGCCTCTGGAATTTAGCGCTCGCCCAGCTAGCCGCAG
AAATGACTGCTGTCCATGCAGGCAACATAAACTTCAAGTGGGATCCTAAAAGTCTAGAGATCAGGACTCTGGCAGTTGAGAGACTGTTGG
AGCCTCTTGTTACACAGGTGATTTGATGAAGGCTGCTGCAGGAGAGTTCGCAGATGATCCCTGCTCTTCTGTGAAGCGAGGCAACATGGT
TCGGGCAGCTCGAGCTTTGCTCTCTGCTGTTACCCGGTTGCTGATTTTGGCTGACATGGCAGATGTCTACAAATTACTTGTTCAGCTGAA
AGTTGTGGAAGATGGTATCTTGAAGTTGAGGAATGCTGGCAATGAACAAGACTTAGGAATCCAGTATAAAGCCCTAAAACCTGAAGTGGA
TAAGCTGAACATTATGGCAGCCAAAAGACAACAGGAATTGAAAGATGTTGGCCATCGTGATCAGATGGCTGCAGCTAGAGGAATCCTGCA
GAAGAACGTTCCGATCCTCTATACTGCATCCCAGGCATGCCTACAGCACCCTGATGTCGCAGCCTATAAGGCCAACAGGGACCTGATATA
CAAGCAGCTGCAGCAGGCGGTCACAGGCATTTCCAATGCAGCCCAGGCCACTGCCTCAGACGATGCCTCACAGCACCAGGGTGGAGGAGG
AGGAGAACTGGCATATGCACTCAATAACTTTGACAAACAAATCATTGTGGACCCCTTGAGCTTCAGCGAGGAGCGCTTTAGGCCTTCCCT
GGAGGAGCGTCTGGAAAGCATCATTAGTGGGGCTGCCTTGATGGCCGACTCGTCCTGCACGCGTGATGACCGTCGTGAGCGAATTGTGGC
AGAGTGTAATGCTGTCCGCCAGGCCCTGCAGGACCTGCTTTCGGAGTACATGGGCAATATCTTTGTAGAATTTGATGGCTGTAACTGGAA
GCAACACTCCTGGGTAAAAGTTCATGCTGAGGAAGTTATCGTGCTTCTGCTGGAAGGGTCTCTTGTATGGGCGCCCCGTGAGGACCCAGT
CCTTCTCCAGGGCATTCGAGTCTCCATTGCACAATGGCCAGCCCTGACTTTTACTCCCCTTGTAGATAAACTGGGTTTGGGTTCTGTGGT
TCCAGTGGAATATCTTCTGGATCGAGAGCTTCGGTTCCTGTCAGATGCCAATGGGTTGCATCTGTTTCAGATGGGAACAGATAGCCAAAA
CCAGATTCTTTTGGAACATGCTGCACTGAGAGAAACAGTTAATGCTTTGATCAGTGACCAAAAGCTACAAGAGATATTCAGCCGAGGTCC
CTACAGTGTTCAAGGTCACAGGGTCAAAATATATCAGCCAGAGGGGGAAGAAGGGTGGCTCTATGGTGTTGTGAGCCATCAGGACTCCAT
CACTCGTCTTATGGAGGTGTCTGTAACTGAGAGTGGTGAGATCAAGTCGGTAGATCCCAGACTAATCCATGTGATGCTGATGGATAATTC
AGCGCCTCAAAGCGAGGGGGGTACGTTAAAAGCAGTAAAATCTTCCAAAGGAAAGAAGAAGAGAGAAAGCATAGAGGGGAAAGATGGCCG
GAGGAGGAAAAGTGCTTCGGACTCTGGGTGTGACCCTGCATCAAAGAAATTAAAAGGAGACAGGGGTGAAGTAGACAGTAATGGGAGCGA
TGGAGGTGAGGCAAGCCGAGGGCCCTGGAAAGGAGGGAATGCCAGTGGAGAGCCAGGGCTGGATCAGAGAGCCAAGCAGCCACCGTCTAC
ATTTGTCCCCCAGATAAACCGCAACATTCGCTTTGCCACTTACACCAAAGAAAACGGCAGGACTCTGGTGGTGCAGGATGAGCCTGTAGG
TGGGGACACACCTGCATCTTTCACTCCATATTCTACAGCCACAGGTCAGACACCTTTGGCCCCAGAGGTGGGTGGAGCCGAAAACAAAGA
GGCAGGAAAAACACTGGAACAAGTTGGCCAGGGCATAGTGGCTTCCGCAGCTGTGGTCACTACCGCCAGCTCCACCCCAAACACAGTGAG
GATCTCAGACACTGGCCTTGCAGCAGGGACTGTGCCAGAAAAACAGAAAGGCAGCCGGTCGCAGGCCTCGGGAGAGAATTCAAGAAATTC
TATTCTGGCCTCTTCTGGATTTGGAGCACCTCTCCCTAGTTCATCGCAACCTTTGACTTTTGGAAGTGGAAGGAGCCAGTCCAATGGTGT
TCTAGCCACAGAGAACAAACCTTTGGGCTTCTCTTTTGGCTGTAGCTCTGCACAAGAGGCACAGAAAGACACTGATCTCTCCAAAAACTT
GTTTTTTCAATGCATGTCCCAAACTTTACCTACCAGTAACTACTTCACTACTGTTTCAGAGAGTTTGGCTGATGATTCTTCTAGTCGGGA
CTCATTCAAACAAAGCCTTGAGAGCCTGAGCTCAGGCCTGTGTAAAGGCAGATCCGTTCTTGGAACAGACACTAAGCCAGGCTCTAAGGC
TGGCAGCTCTGTGGACCGGAAAGTGCCTGCAGAGTCCATGCCCACCCTCACTCCAGCCTTCCCACGGAGCCTCCTAAATGCCCGTACCCC
AGAGAATCATGAAAATCTATTTTTACAGCCCCCCAAATTGTCCCGAGAAGAGCCTTCTAATCCTTTCCTGGCATTTGTGGAGAAAGTTGA
ACACAGCCCTTTCAGTAGTTTTGCATCTCAGGCATCAGGTAGCTCCTCTTCTGCTACCACTGTCACCTCCAAGGTGGCACCCAGCTGGCC
CGAGTCTCACTCCTCTGCAGATTCGGCATCTTTAGCAAAGAAGAAACCCCTCTTCATTACAACTGACTCCTCCAAGCTAGTATCTGGTGT
TCTGGGCTCAGCTCTTACCAGTGGGGGCCCAAGCCTCTCTGCCATGGGGAATGGCCGCTCCAGCTCGCCCACCAGCAGCCTCACTCAGCC
CATTGAGATGCCAACTCTCTCCTCTAGCCCCACAGAGGAGAGGCCAACTGTGGGGCCTGGGCAGCAGGACAATCCCCTCCTCAAAACCTT
TAGTAACGTCTTTGGCAGGCACTCAGGCGGCTTTCTGTCCTCCCCGGCAGATTTTTCACAGGAGAACAAAGCTCCTTTTGAAGCTGTGAA
AAGGTTCTCACTGGATGAACGAAGCTTGGCTTGCAGACAAGACTCGGACTCCAGCACCAACAGTGACCTGTCAGATTTGAGTGACTCTGA
GGAGCAGCTGCAGGCTAAGACAGGCCTGAAGGGAATTCCAGAGCACCTGATGGGGAAGCTGGGCCCCAATGGGGAGCGCAGTGCTGAGCT
GTTGCTGGGCAAAAGCAAAGGGAAGCAGGCCCCCAAGGGCCGGCCTCGGACTGCCCCCCTGAAAGTTGGCCAGTCAGTGCTGAAAGATGT
AAGCAAAGTGAAGAAGCTGAAGCAATCTGGAGAGCCCTTCCTGCAGGATGGGTCATGCATCAATGTGGCACCTCATCTGCACAAGTGTCG
TGAATGCCGCCTGGAGCGGTACCGGAAGTTTAAGGAACAGGAGCAAGATGATTCTACTGTAGCCTGCCGTTTCTTTCACTTCCGGAGGTT
GATCTTCACTCGAAAAGGGGTACTCCGTGTGGAGGGGTTTTTAAGCCCCCAGCAAAGTGACCCTGATGCCATGAACCTGTGGATTCCCTC
TTCCTCCCTAGCAGAAGGGATAGATCTAGAGACCTCAAAATACATCCTGGCCAATGTTGGGGACCAGTTCTGCCAGCTCGTAATGTCTGA
GAAGGAGGCCATGATGATGGTGGAGCCACACCAGAAAGTGGCATGGAAGCGAGCTGTGCGTGGTGTACGGGAGATGTGTGATGTGTGTGA
AACAACTCTCTTCAACATCCACTGGGTTTGTCGCAAATGTGGATTTGGGGTCTGCCTTGACTGTTACCGGCTCAGGAAAAGCCGGCCACG
CAGTGAGACAGAAGAGATGGGTGATGAAGAAGTTTTCTCCTGGTTGAAGTGTGCAAAGGGACAGTCCCACGAACCAGAGAATCTCATGCC
CACACAAATTATTCCTGGCACAGCTCTTTACAATATTGGAGACATGGTACATGCTGCCCGGGGCAAGTGGGGAATTAAAGCAAACTGCCC
TTGTATCAGTCGACAGAACAAATCTGTATTGAGACCTGCCGTCACCAATGGGATGTCACAGCTTCCTAGCATAAACCCTAGTGCCTCTTC
TGGAAACGAAACTACCTTCTCTGGTGGAGGAGGACCGGCACCAGTAACAACTCCAGAGCCGGACCATGTTCCCAAAGCCGACAGCACTGA
CATCAGATCTGAAGAGCCTCTGAAAACAGACAGTTCGGCATCAAATAGCAATAGTGAACTGAAAGCCATCAGGCCTCCTTGCCCTGACAC
GGCCCCACCCTCCTCCGCCCTGCACTGGTTGGCAGATTTAGCAACTCAGAAGGCTAAAGAAGAAACAAAAGAAGCAGGGTCCCTGAGGTC
GGTGCTCAATAAAGAGTCTCATTCACCCTTTGGGCTGGACTCGTTCAACTCCACTGCAAAGGTCTCTCCGCTGACTCCAAAGCTTTTTAA
CAGTCTGTTGCTGGGTCCCACTGCCTCCAACAACAAAACCGAAGGGTCTAGCCTTCGAGACCTCCTTCACTCCGGGCCGGGAAAACTTCC
TCAAACCCCCTTGGACACAGGCATACCCTTTCCCCCGGTCTTCTCTACATCCTCAGCAGGAGTGAAGAGCAAGGCCAGCCTACCCAACTT
TCTTGACCACATCATTGCCTCAGTGGTAGAAAATAAGAAAACCTCAGATGCTTCAAAGCGGGCCTGCAACTTGACTGATACCCAGAAGGA
AGTGAAGGAGATGGTGATGGGGTTAAATGTGCTAGATCCCCATACTTCTCACTCCTGGCTTTGTGATGGGAGGCTTCTGTGTCTCCATGA
CCCCAGCAACAAAAACAATTGGAAGATCTTCCGGGAGTGTTGGAAGCAAGGTCAGCCAGTGCTGGTTTCGGGGGTACATAAAAAGCTCAA
GTCTGAGCTCTGGAAGCCAGAAGCCTTTAGCCAGGAATTTGGAGACCAGGATGTAGACTTGGTGAACTGCAGGAACTGTGCTATAATTTC
CGATGTGAAAGTTCGGGATTTCTGGGATGGTTTCGAGATCATATGCAAACGACTACGGTCAGAAGATGGGCAGCCAATGGTGCTCAAACT
CAAGGACTGGCCTCCTGGGGAAGATTTTCGAGACATGATGCCAACCAGGTTTGAAGATCTGATGGAGAACCTTCCTCTGCCAGAATATAC
CAAACGAGATGGCAGGCTCAATCTGGCCTCTAGGCTACCTAGCTACTTTGTAAGGCCTGATCTGGGCCCCAAGATGTACAACGCCTATGG
GTTGATAACAGCAGAAGATAGAAGAGTTGGTACAACAAATCTTCACTTAGATGTGTCTGATGCTGTTAATGTGATGGTGTATGTTGGGAT
TCCCATCGGGGAGGGTGCTCATGATGAAGAGGTACTCAAGACAATTGACGAGGGAGATGCCGATGAGGTGACGAAGCAGAGGATTCATGA
TGGAAAAGAGAAGCCAGGTGCTTTATGGCACATCTATGCAGCCAAGGATGCAGAGAAGATCCGGGAGCTGCTCCGAAAGGTTGGAGAAGA
ACAAGGCCAAGAGAACCCCCCTGATCATGACCCAATTCATGACCAAAGTTGGTACCTGGACCAGACCCTCCGTAAGCGACTCTATGAGGA
GTATGGCGTGCAAGGCTGGGCTATTGTGCAGTTCCTAGGTGATGCTGTTTTCATACCTGCTGGAGCCCCACACCAGGTTCACAATCTATA
CAGTTGCATAAAAGTAGCAGAAGACTTTGTATCTCCAGAACATGTAAAGCACTGTTTCCGCCTGACTCAGGAATTCAGGCATCTCTCTAA
CACTCATACAAATCATGAGGATAAACTGCAGGTGAAGAACATCATTTACCATGCAGTGAAAGATGCGGTTGGCACCCTCAAGGCTCATGA
ATCCAAACTGGCAAGGTCCTAGGCATGGAGAAACTCCAAGCTCCTCTGTGAAGCAGGTCTTTCACTCACAACACTTAACAGGGAACGGCA
GGGCTCTTTGCTGGAGCAGAGGCCCTTCACCCAGAGCCAGTGTGGTCAGTATTCCAAACTCTCCAGCCACTCTCTTCTACGCTGCCTCAA
CACTGAAGGTTGACACAGGAAAGTCGTACTGTTCACACACACAGTTTGAGACTCCAAGCCAAGAGTGCCACATCCCTATCCTGTGGCCTT
TTGGAAATCCAAATTGCCTGAACATGGCGGGGCTTTCCTGCACATTCTCCTGATTTGAGATTCACGGGCACACCTTTCTTTTCTTTTCCT
CTTGTGCCTAGTTAAGTGGAAATGTGTTTGGAGATAGGGGAAATCACATAACTGGTACAAGTATGGGGTAATTGCTTAAACATGCCTGGT
GGAAGTCTGATAGCGTCTCTGCACGTGACCTCTGACAAAGCCCATCCCAGGAGACGGGGTGAAGCTATTCCCCACACTCTCCTGTGAACA
CTGGAGTCTTGCAAGACCCAGGGAGAACCCACTGCTTTTCCCAGGAGGCTCCAGGATTAGGAAATGTGTGTATTTAGTGAAAAATAGGTT
TGTAGTGAAATAGTTACTATTTCATGAAAGTAGATATTTTTAGAATTTTTGAAATACCACAGTTGTTTTCCTGGATTATAAGGAAAGGCA
CATTACATTTAGTCTTCCTTTCGATATAAAACTCTTTGAAGAAATATGATTTTTAGAAATCAGCTACCCATTATAGCACAAAATCAGCCA
AAGCAGAATTTTTAAAAATTGGCTTTTTTAGGATTCTTTTTCTCCCCCTCCCATCTTAGTCTTACCTTGAGGGAACAGTCATATGAGAAG
GAACTTTGTCACATCTAAGCTGTGGTGTGTTCCCCATGTGTGTGTACAACACTGGTGACTCCAGGAACCATTTTCACCTATTACCAGTGT
TCCCTGGGGACTCCTCTTAATGTTTCCAAATGGGAAGGACAGTTGATTTCCAACATGAGGTTTTTTGTTTTTTATCCAGAAATATTTTCA
GCAAAACTTTCCAACTGAGTGGAGTCTGATTAAGGATTTATTTGAAAATGGTGGGATTCATTGGCCCATAGGTACATTGGAAAATGTATA
TCTCTCCAGCTGTACTGTAGTGCCCTGCAGGCTGTTTATATGTTCACAGTTACTTTTTTTTTTTTTTTTAAATAAAAGTCATTTAATGTA

>20259_20259_3_CTNNA1-KDM3B_CTNNA1_chr5_138163407_ENST00000355078_KDM3B_chr5_137708362_ENST00000314358_length(amino acids)=1949AA_BP=252
MMKAAAGEFADDPCSSVKRGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKALKPEVDKLNIMAA
KRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQATASDDASQHQGGGGGELAYAL
NNFDKQIIVDPLSFSEERFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNIFVEFDGCNWKQHSWVKV
HAEEVIVLLLEGSLVWAPREDPVLLQGIRVSIAQWPALTFTPLVDKLGLGSVVPVEYLLDRELRFLSDANGLHLFQMGTDSQNQILLEHA
ALRETVNALISDQKLQEIFSRGPYSVQGHRVKIYQPEGEEGWLYGVVSHQDSITRLMEVSVTESGEIKSVDPRLIHVMLMDNSAPQSEGG
TLKAVKSSKGKKKRESIEGKDGRRRKSASDSGCDPASKKLKGDRGEVDSNGSDGGEASRGPWKGGNASGEPGLDQRAKQPPSTFVPQINR
NIRFATYTKENGRTLVVQDEPVGGDTPASFTPYSTATGQTPLAPEVGGAENKEAGKTLEQVGQGIVASAAVVTTASSTPNTVRISDTGLA
AGTVPEKQKGSRSQASGENSRNSILASSGFGAPLPSSSQPLTFGSGRSQSNGVLATENKPLGFSFGCSSAQEAQKDTDLSKNLFFQCMSQ
TLPTSNYFTTVSESLADDSSSRDSFKQSLESLSSGLCKGRSVLGTDTKPGSKAGSSVDRKVPAESMPTLTPAFPRSLLNARTPENHENLF
LQPPKLSREEPSNPFLAFVEKVEHSPFSSFASQASGSSSSATTVTSKVAPSWPESHSSADSASLAKKKPLFITTDSSKLVSGVLGSALTS
GGPSLSAMGNGRSSSPTSSLTQPIEMPTLSSSPTEERPTVGPGQQDNPLLKTFSNVFGRHSGGFLSSPADFSQENKAPFEAVKRFSLDER
SLACRQDSDSSTNSDLSDLSDSEEQLQAKTGLKGIPEHLMGKLGPNGERSAELLLGKSKGKQAPKGRPRTAPLKVGQSVLKDVSKVKKLK
QSGEPFLQDGSCINVAPHLHKCRECRLERYRKFKEQEQDDSTVACRFFHFRRLIFTRKGVLRVEGFLSPQQSDPDAMNLWIPSSSLAEGI
DLETSKYILANVGDQFCQLVMSEKEAMMMVEPHQKVAWKRAVRGVREMCDVCETTLFNIHWVCRKCGFGVCLDCYRLRKSRPRSETEEMG
DEEVFSWLKCAKGQSHEPENLMPTQIIPGTALYNIGDMVHAARGKWGIKANCPCISRQNKSVLRPAVTNGMSQLPSINPSASSGNETTFS
GGGGPAPVTTPEPDHVPKADSTDIRSEEPLKTDSSASNSNSELKAIRPPCPDTAPPSSALHWLADLATQKAKEETKEAGSLRSVLNKESH
SPFGLDSFNSTAKVSPLTPKLFNSLLLGPTASNNKTEGSSLRDLLHSGPGKLPQTPLDTGIPFPPVFSTSSAGVKSKASLPNFLDHIIAS
VVENKKTSDASKRACNLTDTQKEVKEMVMGLNVLDPHTSHSWLCDGRLLCLHDPSNKNNWKIFRECWKQGQPVLVSGVHKKLKSELWKPE
AFSQEFGDQDVDLVNCRNCAIISDVKVRDFWDGFEIICKRLRSEDGQPMVLKLKDWPPGEDFRDMMPTRFEDLMENLPLPEYTKRDGRLN
LASRLPSYFVRPDLGPKMYNAYGLITAEDRRVGTTNLHLDVSDAVNVMVYVGIPIGEGAHDEEVLKTIDEGDADEVTKQRIHDGKEKPGA
LWHIYAAKDAEKIRELLRKVGEEQGQENPPDHDPIHDQSWYLDQTLRKRLYEEYGVQGWAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAE

--------------------------------------------------------------
>20259_20259_4_CTNNA1-KDM3B_CTNNA1_chr5_138163407_ENST00000355078_KDM3B_chr5_137708363_ENST00000314358_length(transcript)=7379nt_BP=958nt
TTTCCTCCTCCTAGCCGGACTGGAGGGAGACAAAGCAGCGCCCGTCTGCTTCGGGCCTCTGGAATTTAGCGCTCGCCCAGCTAGCCGCAG
AAATGACTGCTGTCCATGCAGGCAACATAAACTTCAAGTGGGATCCTAAAAGTCTAGAGATCAGGACTCTGGCAGTTGAGAGACTGTTGG
AGCCTCTTGTTACACAGGTGATTTGATGAAGGCTGCTGCAGGAGAGTTCGCAGATGATCCCTGCTCTTCTGTGAAGCGAGGCAACATGGT
TCGGGCAGCTCGAGCTTTGCTCTCTGCTGTTACCCGGTTGCTGATTTTGGCTGACATGGCAGATGTCTACAAATTACTTGTTCAGCTGAA
AGTTGTGGAAGATGGTATCTTGAAGTTGAGGAATGCTGGCAATGAACAAGACTTAGGAATCCAGTATAAAGCCCTAAAACCTGAAGTGGA
TAAGCTGAACATTATGGCAGCCAAAAGACAACAGGAATTGAAAGATGTTGGCCATCGTGATCAGATGGCTGCAGCTAGAGGAATCCTGCA
GAAGAACGTTCCGATCCTCTATACTGCATCCCAGGCATGCCTACAGCACCCTGATGTCGCAGCCTATAAGGCCAACAGGGACCTGATATA
CAAGCAGCTGCAGCAGGCGGTCACAGGCATTTCCAATGCAGCCCAGGCCACTGCCTCAGACGATGCCTCACAGCACCAGGGTGGAGGAGG
AGGAGAACTGGCATATGCACTCAATAACTTTGACAAACAAATCATTGTGGACCCCTTGAGCTTCAGCGAGGAGCGCTTTAGGCCTTCCCT
GGAGGAGCGTCTGGAAAGCATCATTAGTGGGGCTGCCTTGATGGCCGACTCGTCCTGCACGCGTGATGACCGTCGTGAGCGAATTGTGGC
AGAGTGTAATGCTGTCCGCCAGGCCCTGCAGGACCTGCTTTCGGAGTACATGGGCAATATCTTTGTAGAATTTGATGGCTGTAACTGGAA
GCAACACTCCTGGGTAAAAGTTCATGCTGAGGAAGTTATCGTGCTTCTGCTGGAAGGGTCTCTTGTATGGGCGCCCCGTGAGGACCCAGT
CCTTCTCCAGGGCATTCGAGTCTCCATTGCACAATGGCCAGCCCTGACTTTTACTCCCCTTGTAGATAAACTGGGTTTGGGTTCTGTGGT
TCCAGTGGAATATCTTCTGGATCGAGAGCTTCGGTTCCTGTCAGATGCCAATGGGTTGCATCTGTTTCAGATGGGAACAGATAGCCAAAA
CCAGATTCTTTTGGAACATGCTGCACTGAGAGAAACAGTTAATGCTTTGATCAGTGACCAAAAGCTACAAGAGATATTCAGCCGAGGTCC
CTACAGTGTTCAAGGTCACAGGGTCAAAATATATCAGCCAGAGGGGGAAGAAGGGTGGCTCTATGGTGTTGTGAGCCATCAGGACTCCAT
CACTCGTCTTATGGAGGTGTCTGTAACTGAGAGTGGTGAGATCAAGTCGGTAGATCCCAGACTAATCCATGTGATGCTGATGGATAATTC
AGCGCCTCAAAGCGAGGGGGGTACGTTAAAAGCAGTAAAATCTTCCAAAGGAAAGAAGAAGAGAGAAAGCATAGAGGGGAAAGATGGCCG
GAGGAGGAAAAGTGCTTCGGACTCTGGGTGTGACCCTGCATCAAAGAAATTAAAAGGAGACAGGGGTGAAGTAGACAGTAATGGGAGCGA
TGGAGGTGAGGCAAGCCGAGGGCCCTGGAAAGGAGGGAATGCCAGTGGAGAGCCAGGGCTGGATCAGAGAGCCAAGCAGCCACCGTCTAC
ATTTGTCCCCCAGATAAACCGCAACATTCGCTTTGCCACTTACACCAAAGAAAACGGCAGGACTCTGGTGGTGCAGGATGAGCCTGTAGG
TGGGGACACACCTGCATCTTTCACTCCATATTCTACAGCCACAGGTCAGACACCTTTGGCCCCAGAGGTGGGTGGAGCCGAAAACAAAGA
GGCAGGAAAAACACTGGAACAAGTTGGCCAGGGCATAGTGGCTTCCGCAGCTGTGGTCACTACCGCCAGCTCCACCCCAAACACAGTGAG
GATCTCAGACACTGGCCTTGCAGCAGGGACTGTGCCAGAAAAACAGAAAGGCAGCCGGTCGCAGGCCTCGGGAGAGAATTCAAGAAATTC
TATTCTGGCCTCTTCTGGATTTGGAGCACCTCTCCCTAGTTCATCGCAACCTTTGACTTTTGGAAGTGGAAGGAGCCAGTCCAATGGTGT
TCTAGCCACAGAGAACAAACCTTTGGGCTTCTCTTTTGGCTGTAGCTCTGCACAAGAGGCACAGAAAGACACTGATCTCTCCAAAAACTT
GTTTTTTCAATGCATGTCCCAAACTTTACCTACCAGTAACTACTTCACTACTGTTTCAGAGAGTTTGGCTGATGATTCTTCTAGTCGGGA
CTCATTCAAACAAAGCCTTGAGAGCCTGAGCTCAGGCCTGTGTAAAGGCAGATCCGTTCTTGGAACAGACACTAAGCCAGGCTCTAAGGC
TGGCAGCTCTGTGGACCGGAAAGTGCCTGCAGAGTCCATGCCCACCCTCACTCCAGCCTTCCCACGGAGCCTCCTAAATGCCCGTACCCC
AGAGAATCATGAAAATCTATTTTTACAGCCCCCCAAATTGTCCCGAGAAGAGCCTTCTAATCCTTTCCTGGCATTTGTGGAGAAAGTTGA
ACACAGCCCTTTCAGTAGTTTTGCATCTCAGGCATCAGGTAGCTCCTCTTCTGCTACCACTGTCACCTCCAAGGTGGCACCCAGCTGGCC
CGAGTCTCACTCCTCTGCAGATTCGGCATCTTTAGCAAAGAAGAAACCCCTCTTCATTACAACTGACTCCTCCAAGCTAGTATCTGGTGT
TCTGGGCTCAGCTCTTACCAGTGGGGGCCCAAGCCTCTCTGCCATGGGGAATGGCCGCTCCAGCTCGCCCACCAGCAGCCTCACTCAGCC
CATTGAGATGCCAACTCTCTCCTCTAGCCCCACAGAGGAGAGGCCAACTGTGGGGCCTGGGCAGCAGGACAATCCCCTCCTCAAAACCTT
TAGTAACGTCTTTGGCAGGCACTCAGGCGGCTTTCTGTCCTCCCCGGCAGATTTTTCACAGGAGAACAAAGCTCCTTTTGAAGCTGTGAA
AAGGTTCTCACTGGATGAACGAAGCTTGGCTTGCAGACAAGACTCGGACTCCAGCACCAACAGTGACCTGTCAGATTTGAGTGACTCTGA
GGAGCAGCTGCAGGCTAAGACAGGCCTGAAGGGAATTCCAGAGCACCTGATGGGGAAGCTGGGCCCCAATGGGGAGCGCAGTGCTGAGCT
GTTGCTGGGCAAAAGCAAAGGGAAGCAGGCCCCCAAGGGCCGGCCTCGGACTGCCCCCCTGAAAGTTGGCCAGTCAGTGCTGAAAGATGT
AAGCAAAGTGAAGAAGCTGAAGCAATCTGGAGAGCCCTTCCTGCAGGATGGGTCATGCATCAATGTGGCACCTCATCTGCACAAGTGTCG
TGAATGCCGCCTGGAGCGGTACCGGAAGTTTAAGGAACAGGAGCAAGATGATTCTACTGTAGCCTGCCGTTTCTTTCACTTCCGGAGGTT
GATCTTCACTCGAAAAGGGGTACTCCGTGTGGAGGGGTTTTTAAGCCCCCAGCAAAGTGACCCTGATGCCATGAACCTGTGGATTCCCTC
TTCCTCCCTAGCAGAAGGGATAGATCTAGAGACCTCAAAATACATCCTGGCCAATGTTGGGGACCAGTTCTGCCAGCTCGTAATGTCTGA
GAAGGAGGCCATGATGATGGTGGAGCCACACCAGAAAGTGGCATGGAAGCGAGCTGTGCGTGGTGTACGGGAGATGTGTGATGTGTGTGA
AACAACTCTCTTCAACATCCACTGGGTTTGTCGCAAATGTGGATTTGGGGTCTGCCTTGACTGTTACCGGCTCAGGAAAAGCCGGCCACG
CAGTGAGACAGAAGAGATGGGTGATGAAGAAGTTTTCTCCTGGTTGAAGTGTGCAAAGGGACAGTCCCACGAACCAGAGAATCTCATGCC
CACACAAATTATTCCTGGCACAGCTCTTTACAATATTGGAGACATGGTACATGCTGCCCGGGGCAAGTGGGGAATTAAAGCAAACTGCCC
TTGTATCAGTCGACAGAACAAATCTGTATTGAGACCTGCCGTCACCAATGGGATGTCACAGCTTCCTAGCATAAACCCTAGTGCCTCTTC
TGGAAACGAAACTACCTTCTCTGGTGGAGGAGGACCGGCACCAGTAACAACTCCAGAGCCGGACCATGTTCCCAAAGCCGACAGCACTGA
CATCAGATCTGAAGAGCCTCTGAAAACAGACAGTTCGGCATCAAATAGCAATAGTGAACTGAAAGCCATCAGGCCTCCTTGCCCTGACAC
GGCCCCACCCTCCTCCGCCCTGCACTGGTTGGCAGATTTAGCAACTCAGAAGGCTAAAGAAGAAACAAAAGAAGCAGGGTCCCTGAGGTC
GGTGCTCAATAAAGAGTCTCATTCACCCTTTGGGCTGGACTCGTTCAACTCCACTGCAAAGGTCTCTCCGCTGACTCCAAAGCTTTTTAA
CAGTCTGTTGCTGGGTCCCACTGCCTCCAACAACAAAACCGAAGGGTCTAGCCTTCGAGACCTCCTTCACTCCGGGCCGGGAAAACTTCC
TCAAACCCCCTTGGACACAGGCATACCCTTTCCCCCGGTCTTCTCTACATCCTCAGCAGGAGTGAAGAGCAAGGCCAGCCTACCCAACTT
TCTTGACCACATCATTGCCTCAGTGGTAGAAAATAAGAAAACCTCAGATGCTTCAAAGCGGGCCTGCAACTTGACTGATACCCAGAAGGA
AGTGAAGGAGATGGTGATGGGGTTAAATGTGCTAGATCCCCATACTTCTCACTCCTGGCTTTGTGATGGGAGGCTTCTGTGTCTCCATGA
CCCCAGCAACAAAAACAATTGGAAGATCTTCCGGGAGTGTTGGAAGCAAGGTCAGCCAGTGCTGGTTTCGGGGGTACATAAAAAGCTCAA
GTCTGAGCTCTGGAAGCCAGAAGCCTTTAGCCAGGAATTTGGAGACCAGGATGTAGACTTGGTGAACTGCAGGAACTGTGCTATAATTTC
CGATGTGAAAGTTCGGGATTTCTGGGATGGTTTCGAGATCATATGCAAACGACTACGGTCAGAAGATGGGCAGCCAATGGTGCTCAAACT
CAAGGACTGGCCTCCTGGGGAAGATTTTCGAGACATGATGCCAACCAGGTTTGAAGATCTGATGGAGAACCTTCCTCTGCCAGAATATAC
CAAACGAGATGGCAGGCTCAATCTGGCCTCTAGGCTACCTAGCTACTTTGTAAGGCCTGATCTGGGCCCCAAGATGTACAACGCCTATGG
GTTGATAACAGCAGAAGATAGAAGAGTTGGTACAACAAATCTTCACTTAGATGTGTCTGATGCTGTTAATGTGATGGTGTATGTTGGGAT
TCCCATCGGGGAGGGTGCTCATGATGAAGAGGTACTCAAGACAATTGACGAGGGAGATGCCGATGAGGTGACGAAGCAGAGGATTCATGA
TGGAAAAGAGAAGCCAGGTGCTTTATGGCACATCTATGCAGCCAAGGATGCAGAGAAGATCCGGGAGCTGCTCCGAAAGGTTGGAGAAGA
ACAAGGCCAAGAGAACCCCCCTGATCATGACCCAATTCATGACCAAAGTTGGTACCTGGACCAGACCCTCCGTAAGCGACTCTATGAGGA
GTATGGCGTGCAAGGCTGGGCTATTGTGCAGTTCCTAGGTGATGCTGTTTTCATACCTGCTGGAGCCCCACACCAGGTTCACAATCTATA
CAGTTGCATAAAAGTAGCAGAAGACTTTGTATCTCCAGAACATGTAAAGCACTGTTTCCGCCTGACTCAGGAATTCAGGCATCTCTCTAA
CACTCATACAAATCATGAGGATAAACTGCAGGTGAAGAACATCATTTACCATGCAGTGAAAGATGCGGTTGGCACCCTCAAGGCTCATGA
ATCCAAACTGGCAAGGTCCTAGGCATGGAGAAACTCCAAGCTCCTCTGTGAAGCAGGTCTTTCACTCACAACACTTAACAGGGAACGGCA
GGGCTCTTTGCTGGAGCAGAGGCCCTTCACCCAGAGCCAGTGTGGTCAGTATTCCAAACTCTCCAGCCACTCTCTTCTACGCTGCCTCAA
CACTGAAGGTTGACACAGGAAAGTCGTACTGTTCACACACACAGTTTGAGACTCCAAGCCAAGAGTGCCACATCCCTATCCTGTGGCCTT
TTGGAAATCCAAATTGCCTGAACATGGCGGGGCTTTCCTGCACATTCTCCTGATTTGAGATTCACGGGCACACCTTTCTTTTCTTTTCCT
CTTGTGCCTAGTTAAGTGGAAATGTGTTTGGAGATAGGGGAAATCACATAACTGGTACAAGTATGGGGTAATTGCTTAAACATGCCTGGT
GGAAGTCTGATAGCGTCTCTGCACGTGACCTCTGACAAAGCCCATCCCAGGAGACGGGGTGAAGCTATTCCCCACACTCTCCTGTGAACA
CTGGAGTCTTGCAAGACCCAGGGAGAACCCACTGCTTTTCCCAGGAGGCTCCAGGATTAGGAAATGTGTGTATTTAGTGAAAAATAGGTT
TGTAGTGAAATAGTTACTATTTCATGAAAGTAGATATTTTTAGAATTTTTGAAATACCACAGTTGTTTTCCTGGATTATAAGGAAAGGCA
CATTACATTTAGTCTTCCTTTCGATATAAAACTCTTTGAAGAAATATGATTTTTAGAAATCAGCTACCCATTATAGCACAAAATCAGCCA
AAGCAGAATTTTTAAAAATTGGCTTTTTTAGGATTCTTTTTCTCCCCCTCCCATCTTAGTCTTACCTTGAGGGAACAGTCATATGAGAAG
GAACTTTGTCACATCTAAGCTGTGGTGTGTTCCCCATGTGTGTGTACAACACTGGTGACTCCAGGAACCATTTTCACCTATTACCAGTGT
TCCCTGGGGACTCCTCTTAATGTTTCCAAATGGGAAGGACAGTTGATTTCCAACATGAGGTTTTTTGTTTTTTATCCAGAAATATTTTCA
GCAAAACTTTCCAACTGAGTGGAGTCTGATTAAGGATTTATTTGAAAATGGTGGGATTCATTGGCCCATAGGTACATTGGAAAATGTATA
TCTCTCCAGCTGTACTGTAGTGCCCTGCAGGCTGTTTATATGTTCACAGTTACTTTTTTTTTTTTTTTTAAATAAAAGTCATTTAATGTA

>20259_20259_4_CTNNA1-KDM3B_CTNNA1_chr5_138163407_ENST00000355078_KDM3B_chr5_137708363_ENST00000314358_length(amino acids)=1949AA_BP=252
MMKAAAGEFADDPCSSVKRGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKALKPEVDKLNIMAA
KRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQATASDDASQHQGGGGGELAYAL
NNFDKQIIVDPLSFSEERFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNIFVEFDGCNWKQHSWVKV
HAEEVIVLLLEGSLVWAPREDPVLLQGIRVSIAQWPALTFTPLVDKLGLGSVVPVEYLLDRELRFLSDANGLHLFQMGTDSQNQILLEHA
ALRETVNALISDQKLQEIFSRGPYSVQGHRVKIYQPEGEEGWLYGVVSHQDSITRLMEVSVTESGEIKSVDPRLIHVMLMDNSAPQSEGG
TLKAVKSSKGKKKRESIEGKDGRRRKSASDSGCDPASKKLKGDRGEVDSNGSDGGEASRGPWKGGNASGEPGLDQRAKQPPSTFVPQINR
NIRFATYTKENGRTLVVQDEPVGGDTPASFTPYSTATGQTPLAPEVGGAENKEAGKTLEQVGQGIVASAAVVTTASSTPNTVRISDTGLA
AGTVPEKQKGSRSQASGENSRNSILASSGFGAPLPSSSQPLTFGSGRSQSNGVLATENKPLGFSFGCSSAQEAQKDTDLSKNLFFQCMSQ
TLPTSNYFTTVSESLADDSSSRDSFKQSLESLSSGLCKGRSVLGTDTKPGSKAGSSVDRKVPAESMPTLTPAFPRSLLNARTPENHENLF
LQPPKLSREEPSNPFLAFVEKVEHSPFSSFASQASGSSSSATTVTSKVAPSWPESHSSADSASLAKKKPLFITTDSSKLVSGVLGSALTS
GGPSLSAMGNGRSSSPTSSLTQPIEMPTLSSSPTEERPTVGPGQQDNPLLKTFSNVFGRHSGGFLSSPADFSQENKAPFEAVKRFSLDER
SLACRQDSDSSTNSDLSDLSDSEEQLQAKTGLKGIPEHLMGKLGPNGERSAELLLGKSKGKQAPKGRPRTAPLKVGQSVLKDVSKVKKLK
QSGEPFLQDGSCINVAPHLHKCRECRLERYRKFKEQEQDDSTVACRFFHFRRLIFTRKGVLRVEGFLSPQQSDPDAMNLWIPSSSLAEGI
DLETSKYILANVGDQFCQLVMSEKEAMMMVEPHQKVAWKRAVRGVREMCDVCETTLFNIHWVCRKCGFGVCLDCYRLRKSRPRSETEEMG
DEEVFSWLKCAKGQSHEPENLMPTQIIPGTALYNIGDMVHAARGKWGIKANCPCISRQNKSVLRPAVTNGMSQLPSINPSASSGNETTFS
GGGGPAPVTTPEPDHVPKADSTDIRSEEPLKTDSSASNSNSELKAIRPPCPDTAPPSSALHWLADLATQKAKEETKEAGSLRSVLNKESH
SPFGLDSFNSTAKVSPLTPKLFNSLLLGPTASNNKTEGSSLRDLLHSGPGKLPQTPLDTGIPFPPVFSTSSAGVKSKASLPNFLDHIIAS
VVENKKTSDASKRACNLTDTQKEVKEMVMGLNVLDPHTSHSWLCDGRLLCLHDPSNKNNWKIFRECWKQGQPVLVSGVHKKLKSELWKPE
AFSQEFGDQDVDLVNCRNCAIISDVKVRDFWDGFEIICKRLRSEDGQPMVLKLKDWPPGEDFRDMMPTRFEDLMENLPLPEYTKRDGRLN
LASRLPSYFVRPDLGPKMYNAYGLITAEDRRVGTTNLHLDVSDAVNVMVYVGIPIGEGAHDEEVLKTIDEGDADEVTKQRIHDGKEKPGA
LWHIYAAKDAEKIRELLRKVGEEQGQENPPDHDPIHDQSWYLDQTLRKRLYEEYGVQGWAIVQFLGDAVFIPAGAPHQVHNLYSCIKVAE

--------------------------------------------------------------
>20259_20259_5_CTNNA1-KDM3B_CTNNA1_chr5_138163407_ENST00000518825_KDM3B_chr5_137708362_ENST00000314358_length(transcript)=7485nt_BP=1064nt
AAATGACTGCTGTCCATGCAGGCAACATAAACTTCAAGTGGGATCCTAAAAGTCTAGAGATCAGGACTCTGGCAGTTGAGAGACTGTTGG
AGCCTCTTGTTACACAGGTTACAACCCTTGTAAACACCAATAGTAAAGGGCCCTCTAATAAGAAGAGAGGTCGTTCTAAGAAGGCCCATG
TTTTGGCTGCATCTGTTGAACAAGCAACTGAGAATTTCTTGGAGAAGGGGGATAAAATTGCGAAGGAGAGCCAGTTTCTCAAGGAGGAGC
TTGTGGCTGCTGTAGAAGATGTTCGAAAACAAGGTGATTTGATGAAGGCTGCTGCAGGAGAGTTCGCAGATGATCCCTGCTCTTCTGTGA
AGCGAGGCAACATGGTTCGGGCAGCTCGAGCTTTGCTCTCTGCTGTTACCCGGTTGCTGATTTTGGCTGACATGGCAGATGTCTACAAAT
TACTTGTTCAGCTGAAAGTTGTGGAAGATGGTATCTTGAAGTTGAGGAATGCTGGCAATGAACAAGACTTAGGAATCCAGTATAAAGCCC
TAAAACCTGAAGTGGATAAGCTGAACATTATGGCAGCCAAAAGACAACAGGAATTGAAAGATGTTGGCCATCGTGATCAGATGGCTGCAG
CTAGAGGAATCCTGCAGAAGAACGTTCCGATCCTCTATACTGCATCCCAGGCATGCCTACAGCACCCTGATGTCGCAGCCTATAAGGCCA
ACAGGGACCTGATATACAAGCAGCTGCAGCAGGCGGTCACAGGCATTTCCAATGCAGCCCAGGCCACTGCCTCAGACGATGCCTCACAGC
ACCAGGGTGGAGGAGGAGGAGAACTGGCATATGCACTCAATAACTTTGACAAACAAATCATTGTGGACCCCTTGAGCTTCAGCGAGGAGC
GCTTTAGGCCTTCCCTGGAGGAGCGTCTGGAAAGCATCATTAGTGGGGCTGCCTTGATGGCCGACTCGTCCTGCACGCGTGATGACCGTC
GTGAGCGAATTGTGGCAGAGTGTAATGCTGTCCGCCAGGCCCTGCAGGACCTGCTTTCGGAGTACATGGGCAATATCTTTGTAGAATTTG
ATGGCTGTAACTGGAAGCAACACTCCTGGGTAAAAGTTCATGCTGAGGAAGTTATCGTGCTTCTGCTGGAAGGGTCTCTTGTATGGGCGC
CCCGTGAGGACCCAGTCCTTCTCCAGGGCATTCGAGTCTCCATTGCACAATGGCCAGCCCTGACTTTTACTCCCCTTGTAGATAAACTGG
GTTTGGGTTCTGTGGTTCCAGTGGAATATCTTCTGGATCGAGAGCTTCGGTTCCTGTCAGATGCCAATGGGTTGCATCTGTTTCAGATGG
GAACAGATAGCCAAAACCAGATTCTTTTGGAACATGCTGCACTGAGAGAAACAGTTAATGCTTTGATCAGTGACCAAAAGCTACAAGAGA
TATTCAGCCGAGGTCCCTACAGTGTTCAAGGTCACAGGGTCAAAATATATCAGCCAGAGGGGGAAGAAGGGTGGCTCTATGGTGTTGTGA
GCCATCAGGACTCCATCACTCGTCTTATGGAGGTGTCTGTAACTGAGAGTGGTGAGATCAAGTCGGTAGATCCCAGACTAATCCATGTGA
TGCTGATGGATAATTCAGCGCCTCAAAGCGAGGGGGGTACGTTAAAAGCAGTAAAATCTTCCAAAGGAAAGAAGAAGAGAGAAAGCATAG
AGGGGAAAGATGGCCGGAGGAGGAAAAGTGCTTCGGACTCTGGGTGTGACCCTGCATCAAAGAAATTAAAAGGAGACAGGGGTGAAGTAG
ACAGTAATGGGAGCGATGGAGGTGAGGCAAGCCGAGGGCCCTGGAAAGGAGGGAATGCCAGTGGAGAGCCAGGGCTGGATCAGAGAGCCA
AGCAGCCACCGTCTACATTTGTCCCCCAGATAAACCGCAACATTCGCTTTGCCACTTACACCAAAGAAAACGGCAGGACTCTGGTGGTGC
AGGATGAGCCTGTAGGTGGGGACACACCTGCATCTTTCACTCCATATTCTACAGCCACAGGTCAGACACCTTTGGCCCCAGAGGTGGGTG
GAGCCGAAAACAAAGAGGCAGGAAAAACACTGGAACAAGTTGGCCAGGGCATAGTGGCTTCCGCAGCTGTGGTCACTACCGCCAGCTCCA
CCCCAAACACAGTGAGGATCTCAGACACTGGCCTTGCAGCAGGGACTGTGCCAGAAAAACAGAAAGGCAGCCGGTCGCAGGCCTCGGGAG
AGAATTCAAGAAATTCTATTCTGGCCTCTTCTGGATTTGGAGCACCTCTCCCTAGTTCATCGCAACCTTTGACTTTTGGAAGTGGAAGGA
GCCAGTCCAATGGTGTTCTAGCCACAGAGAACAAACCTTTGGGCTTCTCTTTTGGCTGTAGCTCTGCACAAGAGGCACAGAAAGACACTG
ATCTCTCCAAAAACTTGTTTTTTCAATGCATGTCCCAAACTTTACCTACCAGTAACTACTTCACTACTGTTTCAGAGAGTTTGGCTGATG
ATTCTTCTAGTCGGGACTCATTCAAACAAAGCCTTGAGAGCCTGAGCTCAGGCCTGTGTAAAGGCAGATCCGTTCTTGGAACAGACACTA
AGCCAGGCTCTAAGGCTGGCAGCTCTGTGGACCGGAAAGTGCCTGCAGAGTCCATGCCCACCCTCACTCCAGCCTTCCCACGGAGCCTCC
TAAATGCCCGTACCCCAGAGAATCATGAAAATCTATTTTTACAGCCCCCCAAATTGTCCCGAGAAGAGCCTTCTAATCCTTTCCTGGCAT
TTGTGGAGAAAGTTGAACACAGCCCTTTCAGTAGTTTTGCATCTCAGGCATCAGGTAGCTCCTCTTCTGCTACCACTGTCACCTCCAAGG
TGGCACCCAGCTGGCCCGAGTCTCACTCCTCTGCAGATTCGGCATCTTTAGCAAAGAAGAAACCCCTCTTCATTACAACTGACTCCTCCA
AGCTAGTATCTGGTGTTCTGGGCTCAGCTCTTACCAGTGGGGGCCCAAGCCTCTCTGCCATGGGGAATGGCCGCTCCAGCTCGCCCACCA
GCAGCCTCACTCAGCCCATTGAGATGCCAACTCTCTCCTCTAGCCCCACAGAGGAGAGGCCAACTGTGGGGCCTGGGCAGCAGGACAATC
CCCTCCTCAAAACCTTTAGTAACGTCTTTGGCAGGCACTCAGGCGGCTTTCTGTCCTCCCCGGCAGATTTTTCACAGGAGAACAAAGCTC
CTTTTGAAGCTGTGAAAAGGTTCTCACTGGATGAACGAAGCTTGGCTTGCAGACAAGACTCGGACTCCAGCACCAACAGTGACCTGTCAG
ATTTGAGTGACTCTGAGGAGCAGCTGCAGGCTAAGACAGGCCTGAAGGGAATTCCAGAGCACCTGATGGGGAAGCTGGGCCCCAATGGGG
AGCGCAGTGCTGAGCTGTTGCTGGGCAAAAGCAAAGGGAAGCAGGCCCCCAAGGGCCGGCCTCGGACTGCCCCCCTGAAAGTTGGCCAGT
CAGTGCTGAAAGATGTAAGCAAAGTGAAGAAGCTGAAGCAATCTGGAGAGCCCTTCCTGCAGGATGGGTCATGCATCAATGTGGCACCTC
ATCTGCACAAGTGTCGTGAATGCCGCCTGGAGCGGTACCGGAAGTTTAAGGAACAGGAGCAAGATGATTCTACTGTAGCCTGCCGTTTCT
TTCACTTCCGGAGGTTGATCTTCACTCGAAAAGGGGTACTCCGTGTGGAGGGGTTTTTAAGCCCCCAGCAAAGTGACCCTGATGCCATGA
ACCTGTGGATTCCCTCTTCCTCCCTAGCAGAAGGGATAGATCTAGAGACCTCAAAATACATCCTGGCCAATGTTGGGGACCAGTTCTGCC
AGCTCGTAATGTCTGAGAAGGAGGCCATGATGATGGTGGAGCCACACCAGAAAGTGGCATGGAAGCGAGCTGTGCGTGGTGTACGGGAGA
TGTGTGATGTGTGTGAAACAACTCTCTTCAACATCCACTGGGTTTGTCGCAAATGTGGATTTGGGGTCTGCCTTGACTGTTACCGGCTCA
GGAAAAGCCGGCCACGCAGTGAGACAGAAGAGATGGGTGATGAAGAAGTTTTCTCCTGGTTGAAGTGTGCAAAGGGACAGTCCCACGAAC
CAGAGAATCTCATGCCCACACAAATTATTCCTGGCACAGCTCTTTACAATATTGGAGACATGGTACATGCTGCCCGGGGCAAGTGGGGAA
TTAAAGCAAACTGCCCTTGTATCAGTCGACAGAACAAATCTGTATTGAGACCTGCCGTCACCAATGGGATGTCACAGCTTCCTAGCATAA
ACCCTAGTGCCTCTTCTGGAAACGAAACTACCTTCTCTGGTGGAGGAGGACCGGCACCAGTAACAACTCCAGAGCCGGACCATGTTCCCA
AAGCCGACAGCACTGACATCAGATCTGAAGAGCCTCTGAAAACAGACAGTTCGGCATCAAATAGCAATAGTGAACTGAAAGCCATCAGGC
CTCCTTGCCCTGACACGGCCCCACCCTCCTCCGCCCTGCACTGGTTGGCAGATTTAGCAACTCAGAAGGCTAAAGAAGAAACAAAAGAAG
CAGGGTCCCTGAGGTCGGTGCTCAATAAAGAGTCTCATTCACCCTTTGGGCTGGACTCGTTCAACTCCACTGCAAAGGTCTCTCCGCTGA
CTCCAAAGCTTTTTAACAGTCTGTTGCTGGGTCCCACTGCCTCCAACAACAAAACCGAAGGGTCTAGCCTTCGAGACCTCCTTCACTCCG
GGCCGGGAAAACTTCCTCAAACCCCCTTGGACACAGGCATACCCTTTCCCCCGGTCTTCTCTACATCCTCAGCAGGAGTGAAGAGCAAGG
CCAGCCTACCCAACTTTCTTGACCACATCATTGCCTCAGTGGTAGAAAATAAGAAAACCTCAGATGCTTCAAAGCGGGCCTGCAACTTGA
CTGATACCCAGAAGGAAGTGAAGGAGATGGTGATGGGGTTAAATGTGCTAGATCCCCATACTTCTCACTCCTGGCTTTGTGATGGGAGGC
TTCTGTGTCTCCATGACCCCAGCAACAAAAACAATTGGAAGATCTTCCGGGAGTGTTGGAAGCAAGGTCAGCCAGTGCTGGTTTCGGGGG
TACATAAAAAGCTCAAGTCTGAGCTCTGGAAGCCAGAAGCCTTTAGCCAGGAATTTGGAGACCAGGATGTAGACTTGGTGAACTGCAGGA
ACTGTGCTATAATTTCCGATGTGAAAGTTCGGGATTTCTGGGATGGTTTCGAGATCATATGCAAACGACTACGGTCAGAAGATGGGCAGC
CAATGGTGCTCAAACTCAAGGACTGGCCTCCTGGGGAAGATTTTCGAGACATGATGCCAACCAGGTTTGAAGATCTGATGGAGAACCTTC
CTCTGCCAGAATATACCAAACGAGATGGCAGGCTCAATCTGGCCTCTAGGCTACCTAGCTACTTTGTAAGGCCTGATCTGGGCCCCAAGA
TGTACAACGCCTATGGGTTGATAACAGCAGAAGATAGAAGAGTTGGTACAACAAATCTTCACTTAGATGTGTCTGATGCTGTTAATGTGA
TGGTGTATGTTGGGATTCCCATCGGGGAGGGTGCTCATGATGAAGAGGTACTCAAGACAATTGACGAGGGAGATGCCGATGAGGTGACGA
AGCAGAGGATTCATGATGGAAAAGAGAAGCCAGGTGCTTTATGGCACATCTATGCAGCCAAGGATGCAGAGAAGATCCGGGAGCTGCTCC
GAAAGGTTGGAGAAGAACAAGGCCAAGAGAACCCCCCTGATCATGACCCAATTCATGACCAAAGTTGGTACCTGGACCAGACCCTCCGTA
AGCGACTCTATGAGGAGTATGGCGTGCAAGGCTGGGCTATTGTGCAGTTCCTAGGTGATGCTGTTTTCATACCTGCTGGAGCCCCACACC
AGGTTCACAATCTATACAGTTGCATAAAAGTAGCAGAAGACTTTGTATCTCCAGAACATGTAAAGCACTGTTTCCGCCTGACTCAGGAAT
TCAGGCATCTCTCTAACACTCATACAAATCATGAGGATAAACTGCAGGTGAAGAACATCATTTACCATGCAGTGAAAGATGCGGTTGGCA
CCCTCAAGGCTCATGAATCCAAACTGGCAAGGTCCTAGGCATGGAGAAACTCCAAGCTCCTCTGTGAAGCAGGTCTTTCACTCACAACAC
TTAACAGGGAACGGCAGGGCTCTTTGCTGGAGCAGAGGCCCTTCACCCAGAGCCAGTGTGGTCAGTATTCCAAACTCTCCAGCCACTCTC
TTCTACGCTGCCTCAACACTGAAGGTTGACACAGGAAAGTCGTACTGTTCACACACACAGTTTGAGACTCCAAGCCAAGAGTGCCACATC
CCTATCCTGTGGCCTTTTGGAAATCCAAATTGCCTGAACATGGCGGGGCTTTCCTGCACATTCTCCTGATTTGAGATTCACGGGCACACC
TTTCTTTTCTTTTCCTCTTGTGCCTAGTTAAGTGGAAATGTGTTTGGAGATAGGGGAAATCACATAACTGGTACAAGTATGGGGTAATTG
CTTAAACATGCCTGGTGGAAGTCTGATAGCGTCTCTGCACGTGACCTCTGACAAAGCCCATCCCAGGAGACGGGGTGAAGCTATTCCCCA
CACTCTCCTGTGAACACTGGAGTCTTGCAAGACCCAGGGAGAACCCACTGCTTTTCCCAGGAGGCTCCAGGATTAGGAAATGTGTGTATT
TAGTGAAAAATAGGTTTGTAGTGAAATAGTTACTATTTCATGAAAGTAGATATTTTTAGAATTTTTGAAATACCACAGTTGTTTTCCTGG
ATTATAAGGAAAGGCACATTACATTTAGTCTTCCTTTCGATATAAAACTCTTTGAAGAAATATGATTTTTAGAAATCAGCTACCCATTAT
AGCACAAAATCAGCCAAAGCAGAATTTTTAAAAATTGGCTTTTTTAGGATTCTTTTTCTCCCCCTCCCATCTTAGTCTTACCTTGAGGGA
ACAGTCATATGAGAAGGAACTTTGTCACATCTAAGCTGTGGTGTGTTCCCCATGTGTGTGTACAACACTGGTGACTCCAGGAACCATTTT
CACCTATTACCAGTGTTCCCTGGGGACTCCTCTTAATGTTTCCAAATGGGAAGGACAGTTGATTTCCAACATGAGGTTTTTTGTTTTTTA
TCCAGAAATATTTTCAGCAAAACTTTCCAACTGAGTGGAGTCTGATTAAGGATTTATTTGAAAATGGTGGGATTCATTGGCCCATAGGTA
CATTGGAAAATGTATATCTCTCCAGCTGTACTGTAGTGCCCTGCAGGCTGTTTATATGTTCACAGTTACTTTTTTTTTTTTTTTTAAATA
AAAGTCATTTAATGTAGAATACTTTTAATTTCACTTTCTGTATTTTAATTTTGTTGAAGGGCTGATTGGGATTTCCATGTTCTTATTAAA

>20259_20259_5_CTNNA1-KDM3B_CTNNA1_chr5_138163407_ENST00000518825_KDM3B_chr5_137708362_ENST00000314358_length(amino acids)=2051AA_BP=354
MTAVHAGNINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQATENFLEKGDKIAKESQFLKEEL
VAAVEDVRKQGDLMKAAAGEFADDPCSSVKRGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKAL
KPEVDKLNIMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQATASDDASQH
QGGGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNIFVEFD
GCNWKQHSWVKVHAEEVIVLLLEGSLVWAPREDPVLLQGIRVSIAQWPALTFTPLVDKLGLGSVVPVEYLLDRELRFLSDANGLHLFQMG
TDSQNQILLEHAALRETVNALISDQKLQEIFSRGPYSVQGHRVKIYQPEGEEGWLYGVVSHQDSITRLMEVSVTESGEIKSVDPRLIHVM
LMDNSAPQSEGGTLKAVKSSKGKKKRESIEGKDGRRRKSASDSGCDPASKKLKGDRGEVDSNGSDGGEASRGPWKGGNASGEPGLDQRAK
QPPSTFVPQINRNIRFATYTKENGRTLVVQDEPVGGDTPASFTPYSTATGQTPLAPEVGGAENKEAGKTLEQVGQGIVASAAVVTTASST
PNTVRISDTGLAAGTVPEKQKGSRSQASGENSRNSILASSGFGAPLPSSSQPLTFGSGRSQSNGVLATENKPLGFSFGCSSAQEAQKDTD
LSKNLFFQCMSQTLPTSNYFTTVSESLADDSSSRDSFKQSLESLSSGLCKGRSVLGTDTKPGSKAGSSVDRKVPAESMPTLTPAFPRSLL
NARTPENHENLFLQPPKLSREEPSNPFLAFVEKVEHSPFSSFASQASGSSSSATTVTSKVAPSWPESHSSADSASLAKKKPLFITTDSSK
LVSGVLGSALTSGGPSLSAMGNGRSSSPTSSLTQPIEMPTLSSSPTEERPTVGPGQQDNPLLKTFSNVFGRHSGGFLSSPADFSQENKAP
FEAVKRFSLDERSLACRQDSDSSTNSDLSDLSDSEEQLQAKTGLKGIPEHLMGKLGPNGERSAELLLGKSKGKQAPKGRPRTAPLKVGQS
VLKDVSKVKKLKQSGEPFLQDGSCINVAPHLHKCRECRLERYRKFKEQEQDDSTVACRFFHFRRLIFTRKGVLRVEGFLSPQQSDPDAMN
LWIPSSSLAEGIDLETSKYILANVGDQFCQLVMSEKEAMMMVEPHQKVAWKRAVRGVREMCDVCETTLFNIHWVCRKCGFGVCLDCYRLR
KSRPRSETEEMGDEEVFSWLKCAKGQSHEPENLMPTQIIPGTALYNIGDMVHAARGKWGIKANCPCISRQNKSVLRPAVTNGMSQLPSIN
PSASSGNETTFSGGGGPAPVTTPEPDHVPKADSTDIRSEEPLKTDSSASNSNSELKAIRPPCPDTAPPSSALHWLADLATQKAKEETKEA
GSLRSVLNKESHSPFGLDSFNSTAKVSPLTPKLFNSLLLGPTASNNKTEGSSLRDLLHSGPGKLPQTPLDTGIPFPPVFSTSSAGVKSKA
SLPNFLDHIIASVVENKKTSDASKRACNLTDTQKEVKEMVMGLNVLDPHTSHSWLCDGRLLCLHDPSNKNNWKIFRECWKQGQPVLVSGV
HKKLKSELWKPEAFSQEFGDQDVDLVNCRNCAIISDVKVRDFWDGFEIICKRLRSEDGQPMVLKLKDWPPGEDFRDMMPTRFEDLMENLP
LPEYTKRDGRLNLASRLPSYFVRPDLGPKMYNAYGLITAEDRRVGTTNLHLDVSDAVNVMVYVGIPIGEGAHDEEVLKTIDEGDADEVTK
QRIHDGKEKPGALWHIYAAKDAEKIRELLRKVGEEQGQENPPDHDPIHDQSWYLDQTLRKRLYEEYGVQGWAIVQFLGDAVFIPAGAPHQ

--------------------------------------------------------------
>20259_20259_6_CTNNA1-KDM3B_CTNNA1_chr5_138163407_ENST00000518825_KDM3B_chr5_137708363_ENST00000314358_length(transcript)=7485nt_BP=1064nt
AAATGACTGCTGTCCATGCAGGCAACATAAACTTCAAGTGGGATCCTAAAAGTCTAGAGATCAGGACTCTGGCAGTTGAGAGACTGTTGG
AGCCTCTTGTTACACAGGTTACAACCCTTGTAAACACCAATAGTAAAGGGCCCTCTAATAAGAAGAGAGGTCGTTCTAAGAAGGCCCATG
TTTTGGCTGCATCTGTTGAACAAGCAACTGAGAATTTCTTGGAGAAGGGGGATAAAATTGCGAAGGAGAGCCAGTTTCTCAAGGAGGAGC
TTGTGGCTGCTGTAGAAGATGTTCGAAAACAAGGTGATTTGATGAAGGCTGCTGCAGGAGAGTTCGCAGATGATCCCTGCTCTTCTGTGA
AGCGAGGCAACATGGTTCGGGCAGCTCGAGCTTTGCTCTCTGCTGTTACCCGGTTGCTGATTTTGGCTGACATGGCAGATGTCTACAAAT
TACTTGTTCAGCTGAAAGTTGTGGAAGATGGTATCTTGAAGTTGAGGAATGCTGGCAATGAACAAGACTTAGGAATCCAGTATAAAGCCC
TAAAACCTGAAGTGGATAAGCTGAACATTATGGCAGCCAAAAGACAACAGGAATTGAAAGATGTTGGCCATCGTGATCAGATGGCTGCAG
CTAGAGGAATCCTGCAGAAGAACGTTCCGATCCTCTATACTGCATCCCAGGCATGCCTACAGCACCCTGATGTCGCAGCCTATAAGGCCA
ACAGGGACCTGATATACAAGCAGCTGCAGCAGGCGGTCACAGGCATTTCCAATGCAGCCCAGGCCACTGCCTCAGACGATGCCTCACAGC
ACCAGGGTGGAGGAGGAGGAGAACTGGCATATGCACTCAATAACTTTGACAAACAAATCATTGTGGACCCCTTGAGCTTCAGCGAGGAGC
GCTTTAGGCCTTCCCTGGAGGAGCGTCTGGAAAGCATCATTAGTGGGGCTGCCTTGATGGCCGACTCGTCCTGCACGCGTGATGACCGTC
GTGAGCGAATTGTGGCAGAGTGTAATGCTGTCCGCCAGGCCCTGCAGGACCTGCTTTCGGAGTACATGGGCAATATCTTTGTAGAATTTG
ATGGCTGTAACTGGAAGCAACACTCCTGGGTAAAAGTTCATGCTGAGGAAGTTATCGTGCTTCTGCTGGAAGGGTCTCTTGTATGGGCGC
CCCGTGAGGACCCAGTCCTTCTCCAGGGCATTCGAGTCTCCATTGCACAATGGCCAGCCCTGACTTTTACTCCCCTTGTAGATAAACTGG
GTTTGGGTTCTGTGGTTCCAGTGGAATATCTTCTGGATCGAGAGCTTCGGTTCCTGTCAGATGCCAATGGGTTGCATCTGTTTCAGATGG
GAACAGATAGCCAAAACCAGATTCTTTTGGAACATGCTGCACTGAGAGAAACAGTTAATGCTTTGATCAGTGACCAAAAGCTACAAGAGA
TATTCAGCCGAGGTCCCTACAGTGTTCAAGGTCACAGGGTCAAAATATATCAGCCAGAGGGGGAAGAAGGGTGGCTCTATGGTGTTGTGA
GCCATCAGGACTCCATCACTCGTCTTATGGAGGTGTCTGTAACTGAGAGTGGTGAGATCAAGTCGGTAGATCCCAGACTAATCCATGTGA
TGCTGATGGATAATTCAGCGCCTCAAAGCGAGGGGGGTACGTTAAAAGCAGTAAAATCTTCCAAAGGAAAGAAGAAGAGAGAAAGCATAG
AGGGGAAAGATGGCCGGAGGAGGAAAAGTGCTTCGGACTCTGGGTGTGACCCTGCATCAAAGAAATTAAAAGGAGACAGGGGTGAAGTAG
ACAGTAATGGGAGCGATGGAGGTGAGGCAAGCCGAGGGCCCTGGAAAGGAGGGAATGCCAGTGGAGAGCCAGGGCTGGATCAGAGAGCCA
AGCAGCCACCGTCTACATTTGTCCCCCAGATAAACCGCAACATTCGCTTTGCCACTTACACCAAAGAAAACGGCAGGACTCTGGTGGTGC
AGGATGAGCCTGTAGGTGGGGACACACCTGCATCTTTCACTCCATATTCTACAGCCACAGGTCAGACACCTTTGGCCCCAGAGGTGGGTG
GAGCCGAAAACAAAGAGGCAGGAAAAACACTGGAACAAGTTGGCCAGGGCATAGTGGCTTCCGCAGCTGTGGTCACTACCGCCAGCTCCA
CCCCAAACACAGTGAGGATCTCAGACACTGGCCTTGCAGCAGGGACTGTGCCAGAAAAACAGAAAGGCAGCCGGTCGCAGGCCTCGGGAG
AGAATTCAAGAAATTCTATTCTGGCCTCTTCTGGATTTGGAGCACCTCTCCCTAGTTCATCGCAACCTTTGACTTTTGGAAGTGGAAGGA
GCCAGTCCAATGGTGTTCTAGCCACAGAGAACAAACCTTTGGGCTTCTCTTTTGGCTGTAGCTCTGCACAAGAGGCACAGAAAGACACTG
ATCTCTCCAAAAACTTGTTTTTTCAATGCATGTCCCAAACTTTACCTACCAGTAACTACTTCACTACTGTTTCAGAGAGTTTGGCTGATG
ATTCTTCTAGTCGGGACTCATTCAAACAAAGCCTTGAGAGCCTGAGCTCAGGCCTGTGTAAAGGCAGATCCGTTCTTGGAACAGACACTA
AGCCAGGCTCTAAGGCTGGCAGCTCTGTGGACCGGAAAGTGCCTGCAGAGTCCATGCCCACCCTCACTCCAGCCTTCCCACGGAGCCTCC
TAAATGCCCGTACCCCAGAGAATCATGAAAATCTATTTTTACAGCCCCCCAAATTGTCCCGAGAAGAGCCTTCTAATCCTTTCCTGGCAT
TTGTGGAGAAAGTTGAACACAGCCCTTTCAGTAGTTTTGCATCTCAGGCATCAGGTAGCTCCTCTTCTGCTACCACTGTCACCTCCAAGG
TGGCACCCAGCTGGCCCGAGTCTCACTCCTCTGCAGATTCGGCATCTTTAGCAAAGAAGAAACCCCTCTTCATTACAACTGACTCCTCCA
AGCTAGTATCTGGTGTTCTGGGCTCAGCTCTTACCAGTGGGGGCCCAAGCCTCTCTGCCATGGGGAATGGCCGCTCCAGCTCGCCCACCA
GCAGCCTCACTCAGCCCATTGAGATGCCAACTCTCTCCTCTAGCCCCACAGAGGAGAGGCCAACTGTGGGGCCTGGGCAGCAGGACAATC
CCCTCCTCAAAACCTTTAGTAACGTCTTTGGCAGGCACTCAGGCGGCTTTCTGTCCTCCCCGGCAGATTTTTCACAGGAGAACAAAGCTC
CTTTTGAAGCTGTGAAAAGGTTCTCACTGGATGAACGAAGCTTGGCTTGCAGACAAGACTCGGACTCCAGCACCAACAGTGACCTGTCAG
ATTTGAGTGACTCTGAGGAGCAGCTGCAGGCTAAGACAGGCCTGAAGGGAATTCCAGAGCACCTGATGGGGAAGCTGGGCCCCAATGGGG
AGCGCAGTGCTGAGCTGTTGCTGGGCAAAAGCAAAGGGAAGCAGGCCCCCAAGGGCCGGCCTCGGACTGCCCCCCTGAAAGTTGGCCAGT
CAGTGCTGAAAGATGTAAGCAAAGTGAAGAAGCTGAAGCAATCTGGAGAGCCCTTCCTGCAGGATGGGTCATGCATCAATGTGGCACCTC
ATCTGCACAAGTGTCGTGAATGCCGCCTGGAGCGGTACCGGAAGTTTAAGGAACAGGAGCAAGATGATTCTACTGTAGCCTGCCGTTTCT
TTCACTTCCGGAGGTTGATCTTCACTCGAAAAGGGGTACTCCGTGTGGAGGGGTTTTTAAGCCCCCAGCAAAGTGACCCTGATGCCATGA
ACCTGTGGATTCCCTCTTCCTCCCTAGCAGAAGGGATAGATCTAGAGACCTCAAAATACATCCTGGCCAATGTTGGGGACCAGTTCTGCC
AGCTCGTAATGTCTGAGAAGGAGGCCATGATGATGGTGGAGCCACACCAGAAAGTGGCATGGAAGCGAGCTGTGCGTGGTGTACGGGAGA
TGTGTGATGTGTGTGAAACAACTCTCTTCAACATCCACTGGGTTTGTCGCAAATGTGGATTTGGGGTCTGCCTTGACTGTTACCGGCTCA
GGAAAAGCCGGCCACGCAGTGAGACAGAAGAGATGGGTGATGAAGAAGTTTTCTCCTGGTTGAAGTGTGCAAAGGGACAGTCCCACGAAC
CAGAGAATCTCATGCCCACACAAATTATTCCTGGCACAGCTCTTTACAATATTGGAGACATGGTACATGCTGCCCGGGGCAAGTGGGGAA
TTAAAGCAAACTGCCCTTGTATCAGTCGACAGAACAAATCTGTATTGAGACCTGCCGTCACCAATGGGATGTCACAGCTTCCTAGCATAA
ACCCTAGTGCCTCTTCTGGAAACGAAACTACCTTCTCTGGTGGAGGAGGACCGGCACCAGTAACAACTCCAGAGCCGGACCATGTTCCCA
AAGCCGACAGCACTGACATCAGATCTGAAGAGCCTCTGAAAACAGACAGTTCGGCATCAAATAGCAATAGTGAACTGAAAGCCATCAGGC
CTCCTTGCCCTGACACGGCCCCACCCTCCTCCGCCCTGCACTGGTTGGCAGATTTAGCAACTCAGAAGGCTAAAGAAGAAACAAAAGAAG
CAGGGTCCCTGAGGTCGGTGCTCAATAAAGAGTCTCATTCACCCTTTGGGCTGGACTCGTTCAACTCCACTGCAAAGGTCTCTCCGCTGA
CTCCAAAGCTTTTTAACAGTCTGTTGCTGGGTCCCACTGCCTCCAACAACAAAACCGAAGGGTCTAGCCTTCGAGACCTCCTTCACTCCG
GGCCGGGAAAACTTCCTCAAACCCCCTTGGACACAGGCATACCCTTTCCCCCGGTCTTCTCTACATCCTCAGCAGGAGTGAAGAGCAAGG
CCAGCCTACCCAACTTTCTTGACCACATCATTGCCTCAGTGGTAGAAAATAAGAAAACCTCAGATGCTTCAAAGCGGGCCTGCAACTTGA
CTGATACCCAGAAGGAAGTGAAGGAGATGGTGATGGGGTTAAATGTGCTAGATCCCCATACTTCTCACTCCTGGCTTTGTGATGGGAGGC
TTCTGTGTCTCCATGACCCCAGCAACAAAAACAATTGGAAGATCTTCCGGGAGTGTTGGAAGCAAGGTCAGCCAGTGCTGGTTTCGGGGG
TACATAAAAAGCTCAAGTCTGAGCTCTGGAAGCCAGAAGCCTTTAGCCAGGAATTTGGAGACCAGGATGTAGACTTGGTGAACTGCAGGA
ACTGTGCTATAATTTCCGATGTGAAAGTTCGGGATTTCTGGGATGGTTTCGAGATCATATGCAAACGACTACGGTCAGAAGATGGGCAGC
CAATGGTGCTCAAACTCAAGGACTGGCCTCCTGGGGAAGATTTTCGAGACATGATGCCAACCAGGTTTGAAGATCTGATGGAGAACCTTC
CTCTGCCAGAATATACCAAACGAGATGGCAGGCTCAATCTGGCCTCTAGGCTACCTAGCTACTTTGTAAGGCCTGATCTGGGCCCCAAGA
TGTACAACGCCTATGGGTTGATAACAGCAGAAGATAGAAGAGTTGGTACAACAAATCTTCACTTAGATGTGTCTGATGCTGTTAATGTGA
TGGTGTATGTTGGGATTCCCATCGGGGAGGGTGCTCATGATGAAGAGGTACTCAAGACAATTGACGAGGGAGATGCCGATGAGGTGACGA
AGCAGAGGATTCATGATGGAAAAGAGAAGCCAGGTGCTTTATGGCACATCTATGCAGCCAAGGATGCAGAGAAGATCCGGGAGCTGCTCC
GAAAGGTTGGAGAAGAACAAGGCCAAGAGAACCCCCCTGATCATGACCCAATTCATGACCAAAGTTGGTACCTGGACCAGACCCTCCGTA
AGCGACTCTATGAGGAGTATGGCGTGCAAGGCTGGGCTATTGTGCAGTTCCTAGGTGATGCTGTTTTCATACCTGCTGGAGCCCCACACC
AGGTTCACAATCTATACAGTTGCATAAAAGTAGCAGAAGACTTTGTATCTCCAGAACATGTAAAGCACTGTTTCCGCCTGACTCAGGAAT
TCAGGCATCTCTCTAACACTCATACAAATCATGAGGATAAACTGCAGGTGAAGAACATCATTTACCATGCAGTGAAAGATGCGGTTGGCA
CCCTCAAGGCTCATGAATCCAAACTGGCAAGGTCCTAGGCATGGAGAAACTCCAAGCTCCTCTGTGAAGCAGGTCTTTCACTCACAACAC
TTAACAGGGAACGGCAGGGCTCTTTGCTGGAGCAGAGGCCCTTCACCCAGAGCCAGTGTGGTCAGTATTCCAAACTCTCCAGCCACTCTC
TTCTACGCTGCCTCAACACTGAAGGTTGACACAGGAAAGTCGTACTGTTCACACACACAGTTTGAGACTCCAAGCCAAGAGTGCCACATC
CCTATCCTGTGGCCTTTTGGAAATCCAAATTGCCTGAACATGGCGGGGCTTTCCTGCACATTCTCCTGATTTGAGATTCACGGGCACACC
TTTCTTTTCTTTTCCTCTTGTGCCTAGTTAAGTGGAAATGTGTTTGGAGATAGGGGAAATCACATAACTGGTACAAGTATGGGGTAATTG
CTTAAACATGCCTGGTGGAAGTCTGATAGCGTCTCTGCACGTGACCTCTGACAAAGCCCATCCCAGGAGACGGGGTGAAGCTATTCCCCA
CACTCTCCTGTGAACACTGGAGTCTTGCAAGACCCAGGGAGAACCCACTGCTTTTCCCAGGAGGCTCCAGGATTAGGAAATGTGTGTATT
TAGTGAAAAATAGGTTTGTAGTGAAATAGTTACTATTTCATGAAAGTAGATATTTTTAGAATTTTTGAAATACCACAGTTGTTTTCCTGG
ATTATAAGGAAAGGCACATTACATTTAGTCTTCCTTTCGATATAAAACTCTTTGAAGAAATATGATTTTTAGAAATCAGCTACCCATTAT
AGCACAAAATCAGCCAAAGCAGAATTTTTAAAAATTGGCTTTTTTAGGATTCTTTTTCTCCCCCTCCCATCTTAGTCTTACCTTGAGGGA
ACAGTCATATGAGAAGGAACTTTGTCACATCTAAGCTGTGGTGTGTTCCCCATGTGTGTGTACAACACTGGTGACTCCAGGAACCATTTT
CACCTATTACCAGTGTTCCCTGGGGACTCCTCTTAATGTTTCCAAATGGGAAGGACAGTTGATTTCCAACATGAGGTTTTTTGTTTTTTA
TCCAGAAATATTTTCAGCAAAACTTTCCAACTGAGTGGAGTCTGATTAAGGATTTATTTGAAAATGGTGGGATTCATTGGCCCATAGGTA
CATTGGAAAATGTATATCTCTCCAGCTGTACTGTAGTGCCCTGCAGGCTGTTTATATGTTCACAGTTACTTTTTTTTTTTTTTTTAAATA
AAAGTCATTTAATGTAGAATACTTTTAATTTCACTTTCTGTATTTTAATTTTGTTGAAGGGCTGATTGGGATTTCCATGTTCTTATTAAA

>20259_20259_6_CTNNA1-KDM3B_CTNNA1_chr5_138163407_ENST00000518825_KDM3B_chr5_137708363_ENST00000314358_length(amino acids)=2051AA_BP=354
MTAVHAGNINFKWDPKSLEIRTLAVERLLEPLVTQVTTLVNTNSKGPSNKKRGRSKKAHVLAASVEQATENFLEKGDKIAKESQFLKEEL
VAAVEDVRKQGDLMKAAAGEFADDPCSSVKRGNMVRAARALLSAVTRLLILADMADVYKLLVQLKVVEDGILKLRNAGNEQDLGIQYKAL
KPEVDKLNIMAAKRQQELKDVGHRDQMAAARGILQKNVPILYTASQACLQHPDVAAYKANRDLIYKQLQQAVTGISNAAQATASDDASQH
QGGGGGELAYALNNFDKQIIVDPLSFSEERFRPSLEERLESIISGAALMADSSCTRDDRRERIVAECNAVRQALQDLLSEYMGNIFVEFD
GCNWKQHSWVKVHAEEVIVLLLEGSLVWAPREDPVLLQGIRVSIAQWPALTFTPLVDKLGLGSVVPVEYLLDRELRFLSDANGLHLFQMG
TDSQNQILLEHAALRETVNALISDQKLQEIFSRGPYSVQGHRVKIYQPEGEEGWLYGVVSHQDSITRLMEVSVTESGEIKSVDPRLIHVM
LMDNSAPQSEGGTLKAVKSSKGKKKRESIEGKDGRRRKSASDSGCDPASKKLKGDRGEVDSNGSDGGEASRGPWKGGNASGEPGLDQRAK
QPPSTFVPQINRNIRFATYTKENGRTLVVQDEPVGGDTPASFTPYSTATGQTPLAPEVGGAENKEAGKTLEQVGQGIVASAAVVTTASST
PNTVRISDTGLAAGTVPEKQKGSRSQASGENSRNSILASSGFGAPLPSSSQPLTFGSGRSQSNGVLATENKPLGFSFGCSSAQEAQKDTD
LSKNLFFQCMSQTLPTSNYFTTVSESLADDSSSRDSFKQSLESLSSGLCKGRSVLGTDTKPGSKAGSSVDRKVPAESMPTLTPAFPRSLL
NARTPENHENLFLQPPKLSREEPSNPFLAFVEKVEHSPFSSFASQASGSSSSATTVTSKVAPSWPESHSSADSASLAKKKPLFITTDSSK
LVSGVLGSALTSGGPSLSAMGNGRSSSPTSSLTQPIEMPTLSSSPTEERPTVGPGQQDNPLLKTFSNVFGRHSGGFLSSPADFSQENKAP
FEAVKRFSLDERSLACRQDSDSSTNSDLSDLSDSEEQLQAKTGLKGIPEHLMGKLGPNGERSAELLLGKSKGKQAPKGRPRTAPLKVGQS
VLKDVSKVKKLKQSGEPFLQDGSCINVAPHLHKCRECRLERYRKFKEQEQDDSTVACRFFHFRRLIFTRKGVLRVEGFLSPQQSDPDAMN
LWIPSSSLAEGIDLETSKYILANVGDQFCQLVMSEKEAMMMVEPHQKVAWKRAVRGVREMCDVCETTLFNIHWVCRKCGFGVCLDCYRLR
KSRPRSETEEMGDEEVFSWLKCAKGQSHEPENLMPTQIIPGTALYNIGDMVHAARGKWGIKANCPCISRQNKSVLRPAVTNGMSQLPSIN
PSASSGNETTFSGGGGPAPVTTPEPDHVPKADSTDIRSEEPLKTDSSASNSNSELKAIRPPCPDTAPPSSALHWLADLATQKAKEETKEA
GSLRSVLNKESHSPFGLDSFNSTAKVSPLTPKLFNSLLLGPTASNNKTEGSSLRDLLHSGPGKLPQTPLDTGIPFPPVFSTSSAGVKSKA
SLPNFLDHIIASVVENKKTSDASKRACNLTDTQKEVKEMVMGLNVLDPHTSHSWLCDGRLLCLHDPSNKNNWKIFRECWKQGQPVLVSGV
HKKLKSELWKPEAFSQEFGDQDVDLVNCRNCAIISDVKVRDFWDGFEIICKRLRSEDGQPMVLKLKDWPPGEDFRDMMPTRFEDLMENLP
LPEYTKRDGRLNLASRLPSYFVRPDLGPKMYNAYGLITAEDRRVGTTNLHLDVSDAVNVMVYVGIPIGEGAHDEEVLKTIDEGDADEVTK
QRIHDGKEKPGALWHIYAAKDAEKIRELLRKVGEEQGQENPPDHDPIHDQSWYLDQTLRKRLYEEYGVQGWAIVQFLGDAVFIPAGAPHQ

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Fusion Gene PPI Analysis for CTNNA1-KDM3B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneCTNNA1chr5:138163407chr5:137708362ENST00000302763+71897_148354.0907.0JUP and CTNNB1
HgeneCTNNA1chr5:138163407chr5:137708363ENST00000302763+71897_148354.0907.0JUP and CTNNB1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneCTNNA1chr5:138163407chr5:137708362ENST00000302763+718325_394354.0907.0alpha-actinin
HgeneCTNNA1chr5:138163407chr5:137708362ENST00000540387+112325_3940537.0alpha-actinin
HgeneCTNNA1chr5:138163407chr5:137708363ENST00000302763+718325_394354.0907.0alpha-actinin
HgeneCTNNA1chr5:138163407chr5:137708363ENST00000540387+112325_3940537.0alpha-actinin
HgeneCTNNA1chr5:138163407chr5:137708362ENST00000540387+11297_1480537.0JUP and CTNNB1
HgeneCTNNA1chr5:138163407chr5:137708363ENST00000540387+11297_1480537.0JUP and CTNNB1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CTNNA1-KDM3B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CTNNA1-KDM3B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource