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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CTNNBL1-TSHZ2 (FusionGDB2 ID:20353)

Fusion Gene Summary for CTNNBL1-TSHZ2

check button Fusion gene summary
Fusion gene informationFusion gene name: CTNNBL1-TSHZ2
Fusion gene ID: 20353
HgeneTgene
Gene symbol

CTNNBL1

TSHZ2

Gene ID

56259

128553

Gene namecatenin beta like 1teashirt zinc finger homeobox 2
SynonymsC20orf33|NAP|P14L|PP8304|dJ633O20.1C20orf17|OVC10-2|TSH2|ZABC2|ZNF218
Cytomap

20q11.23

20q13.2

Type of geneprotein-codingprotein-coding
Descriptionbeta-catenin-like protein 1nuclear associated proteintestis development protein NYD-SP19teashirt homolog 2cell growth-inhibiting protein 7ovarian cancer-related protein 10-2serologically defined colon cancer antigen 33 liketeashirt family zinc finger 2zinc finger protein 218
Modification date2020032720200313
UniProtAcc

Q8WYA6

.
Ensembl transtripts involved in fusion geneENST00000473857, ENST00000361383, 
ENST00000373469, ENST00000373473, 
ENST00000405275, 		ENST00000329613, 
ENST00000371497, ENST00000603338, 
Fusion gene scores* DoF score7 X 5 X 5=17540 X 23 X 9=8280
# samples 750
** MAII scorelog2(7/175*10)=-1.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(50/8280*10)=-4.0496307677246
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CTNNBL1 [Title/Abstract] AND TSHZ2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCTNNBL1(36431450)-TSHZ2(51870038), # samples:1
Anticipated loss of major functional domain due to fusion event.CTNNBL1-TSHZ2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CTNNBL1-TSHZ2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
CTNNBL1-TSHZ2 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCTNNBL1

GO:0043065

positive regulation of apoptotic process

12659813


check buttonFusion gene breakpoints across CTNNBL1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TSHZ2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AO-A03M-01BCTNNBL1chr20

36431450

+TSHZ2chr20

51870038

+


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Fusion Gene ORF analysis for CTNNBL1-TSHZ2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000473857ENST00000329613CTNNBL1chr20

36431450

+TSHZ2chr20

51870038

+
3UTR-3CDSENST00000473857ENST00000371497CTNNBL1chr20

36431450

+TSHZ2chr20

51870038

+
3UTR-3CDSENST00000473857ENST00000603338CTNNBL1chr20

36431450

+TSHZ2chr20

51870038

+
Frame-shiftENST00000361383ENST00000329613CTNNBL1chr20

36431450

+TSHZ2chr20

51870038

+
Frame-shiftENST00000373469ENST00000329613CTNNBL1chr20

36431450

+TSHZ2chr20

51870038

+
Frame-shiftENST00000373473ENST00000329613CTNNBL1chr20

36431450

+TSHZ2chr20

51870038

+
Frame-shiftENST00000405275ENST00000329613CTNNBL1chr20

36431450

+TSHZ2chr20

51870038

+
In-frameENST00000361383ENST00000371497CTNNBL1chr20

36431450

+TSHZ2chr20

51870038

+
In-frameENST00000361383ENST00000603338CTNNBL1chr20

36431450

+TSHZ2chr20

51870038

+
In-frameENST00000373469ENST00000371497CTNNBL1chr20

36431450

+TSHZ2chr20

51870038

+
In-frameENST00000373469ENST00000603338CTNNBL1chr20

36431450

+TSHZ2chr20

51870038

+
In-frameENST00000373473ENST00000371497CTNNBL1chr20

36431450

+TSHZ2chr20

51870038

+
In-frameENST00000373473ENST00000603338CTNNBL1chr20

36431450

+TSHZ2chr20

51870038

+
In-frameENST00000405275ENST00000371497CTNNBL1chr20

36431450

+TSHZ2chr20

51870038

+
In-frameENST00000405275ENST00000603338CTNNBL1chr20

36431450

+TSHZ2chr20

51870038

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000361383CTNNBL1chr2036431450+ENST00000371497TSHZ2chr2051870038+12590133011743941425
ENST00000361383CTNNBL1chr2036431450+ENST00000603338TSHZ2chr2051870038+4739133011743941425
ENST00000405275CTNNBL1chr2036431450+ENST00000371497TSHZ2chr2051870038+12635137524344391398
ENST00000405275CTNNBL1chr2036431450+ENST00000603338TSHZ2chr2051870038+4784137524344391398
ENST00000373473CTNNBL1chr2036431450+ENST00000371497TSHZ2chr2051870038+1215889824639621238
ENST00000373473CTNNBL1chr2036431450+ENST00000603338TSHZ2chr2051870038+430789824639621238
ENST00000373469CTNNBL1chr2036431450+ENST00000371497TSHZ2chr2051870038+117955357835991173
ENST00000373469CTNNBL1chr2036431450+ENST00000603338TSHZ2chr2051870038+39445357835991173

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000361383ENST00000371497CTNNBL1chr2036431450+TSHZ2chr2051870038+0.0001773490.9998227
ENST00000361383ENST00000603338CTNNBL1chr2036431450+TSHZ2chr2051870038+0.0012654580.99873453
ENST00000405275ENST00000371497CTNNBL1chr2036431450+TSHZ2chr2051870038+0.000201660.99979836
ENST00000405275ENST00000603338CTNNBL1chr2036431450+TSHZ2chr2051870038+0.0013420580.99865794
ENST00000373473ENST00000371497CTNNBL1chr2036431450+TSHZ2chr2051870038+0.0001858120.9998142
ENST00000373473ENST00000603338CTNNBL1chr2036431450+TSHZ2chr2051870038+0.0014278530.9985721
ENST00000373469ENST00000371497CTNNBL1chr2036431450+TSHZ2chr2051870038+0.0001436710.99985635
ENST00000373469ENST00000603338CTNNBL1chr2036431450+TSHZ2chr2051870038+0.0012971970.99870276

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Fusion Genomic Features for CTNNBL1-TSHZ2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CTNNBL1chr2036431450+TSHZ2chr2051870037+5.07E-131
CTNNBL1chr2036431450+TSHZ2chr2051870037+5.07E-131

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CTNNBL1-TSHZ2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:36431450/chr20:51870038)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CTNNBL1

Q8WYA6

.
FUNCTION: Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated Ig class switching recombination (CSR). May induce apoptosis.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000361383+111622_25404564.0Compositional biasNote=Poly-Glu
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000361383+111668_75404564.0Compositional biasNote=Poly-Glu
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373469+4922_25152312.0Compositional biasNote=Poly-Glu
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373469+4968_75152312.0Compositional biasNote=Poly-Glu
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373473+81322_25217377.0Compositional biasNote=Poly-Glu
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373473+81368_75217377.0Compositional biasNote=Poly-Glu
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000361383+1116130_140404564.0MotifNuclear export signal (NES)
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373469+49130_140152312.0MotifNuclear export signal (NES)
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373473+813130_140217377.0MotifNuclear export signal (NES)
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000361383+1116134_176404564.0RepeatNote=HEAT 2
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000361383+1116178_228404564.0RepeatNote=ARM 1
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000361383+1116229_273404564.0RepeatNote=ARM 2
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000361383+1116274_323404564.0RepeatNote=ARM 3
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000361383+1116325_363404564.0RepeatNote=ARM 4
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000361383+111679_129404564.0RepeatNote=HEAT 1
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373469+4979_129152312.0RepeatNote=HEAT 1
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373473+813134_176217377.0RepeatNote=HEAT 2
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373473+81379_129217377.0RepeatNote=HEAT 1
TgeneTSHZ2chr20:36431450chr20:51870038ENST000003296130213_38101032.0Coiled coilOntology_term=ECO:0000255
TgeneTSHZ2chr20:36431450chr20:51870038ENST000003714970313_38133455.0Coiled coilOntology_term=ECO:0000255
TgeneTSHZ2chr20:36431450chr20:51870038ENST000006033380313_38101012.6666666666666Coiled coilOntology_term=ECO:0000255
TgeneTSHZ2chr20:36431450chr20:51870038ENST0000032961302841_911101032.0DNA bindingNote=Homeobox%3B atypical
TgeneTSHZ2chr20:36431450chr20:51870038ENST0000037149703841_911133455.0DNA bindingNote=Homeobox%3B atypical
TgeneTSHZ2chr20:36431450chr20:51870038ENST0000060333803841_911101012.6666666666666DNA bindingNote=Homeobox%3B atypical
TgeneTSHZ2chr20:36431450chr20:51870038ENST0000032961302215_239101032.0Zinc fingerC2H2-type 1
TgeneTSHZ2chr20:36431450chr20:51870038ENST0000032961302275_299101032.0Zinc fingerC2H2-type 2
TgeneTSHZ2chr20:36431450chr20:51870038ENST0000032961302380_404101032.0Zinc fingerC2H2-type 3%3B atypical
TgeneTSHZ2chr20:36431450chr20:51870038ENST0000032961302926_948101032.0Zinc fingerC2H2-type 4
TgeneTSHZ2chr20:36431450chr20:51870038ENST0000032961302994_1017101032.0Zinc fingerC2H2-type 5
TgeneTSHZ2chr20:36431450chr20:51870038ENST0000037149703215_239133455.0Zinc fingerC2H2-type 1
TgeneTSHZ2chr20:36431450chr20:51870038ENST0000037149703275_299133455.0Zinc fingerC2H2-type 2
TgeneTSHZ2chr20:36431450chr20:51870038ENST0000037149703380_404133455.0Zinc fingerC2H2-type 3%3B atypical
TgeneTSHZ2chr20:36431450chr20:51870038ENST0000037149703926_948133455.0Zinc fingerC2H2-type 4
TgeneTSHZ2chr20:36431450chr20:51870038ENST0000037149703994_1017133455.0Zinc fingerC2H2-type 5
TgeneTSHZ2chr20:36431450chr20:51870038ENST0000060333803215_239101012.6666666666666Zinc fingerC2H2-type 1
TgeneTSHZ2chr20:36431450chr20:51870038ENST0000060333803275_299101012.6666666666666Zinc fingerC2H2-type 2
TgeneTSHZ2chr20:36431450chr20:51870038ENST0000060333803380_404101012.6666666666666Zinc fingerC2H2-type 3%3B atypical
TgeneTSHZ2chr20:36431450chr20:51870038ENST0000060333803926_948101012.6666666666666Zinc fingerC2H2-type 4
TgeneTSHZ2chr20:36431450chr20:51870038ENST0000060333803994_1017101012.6666666666666Zinc fingerC2H2-type 5

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000361383+1116476_540404564.0Coiled coilOntology_term=ECO:0000269
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373469+49476_540152312.0Coiled coilOntology_term=ECO:0000269
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373473+813476_540217377.0Coiled coilOntology_term=ECO:0000269
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000361383+1116364_417404564.0RepeatNote=ARM 5
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373469+49134_176152312.0RepeatNote=HEAT 2
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373469+49178_228152312.0RepeatNote=ARM 1
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373469+49229_273152312.0RepeatNote=ARM 2
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373469+49274_323152312.0RepeatNote=ARM 3
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373469+49325_363152312.0RepeatNote=ARM 4
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373469+49364_417152312.0RepeatNote=ARM 5
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373473+813178_228217377.0RepeatNote=ARM 1
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373473+813229_273217377.0RepeatNote=ARM 2
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373473+813274_323217377.0RepeatNote=ARM 3
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373473+813325_363217377.0RepeatNote=ARM 4
HgeneCTNNBL1chr20:36431450chr20:51870038ENST00000373473+813364_417217377.0RepeatNote=ARM 5


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Fusion Gene Sequence for CTNNBL1-TSHZ2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>20353_20353_1_CTNNBL1-TSHZ2_CTNNBL1_chr20_36431450_ENST00000361383_TSHZ2_chr20_51870038_ENST00000371497_length(transcript)=12590nt_BP=1330nt
ATTGGCTCTGCGGCTCCGCTCGCCGCACTTTACGGCAGTGTGGCTGGAGCCGCGGCTGACGGGCCCGCGGTCTGGGCGTGAGTGCAGGGA
AGTGGAGTATTTGCTGGGCCGGGTACCATGGACGTGGGCGAACTTCTGAGCTACCAGCCCAATAGGGGCACAAAACGTCCCCGGGATGAT
GAAGAGGAGGAGCAGAAGATGCGTCGGAAACAAACTGGTACTCGAGAACGCGGCCGCTATCGGGAAGAAGAAATGACTGTGGTGGAGGAA
GCGGATGATGACAAAAAAAGGCTGCTGCAGATTATTGACAGAGATGGGGAAGAGGAAGAGGAAGAGGAGGAGCCATTGGATGAAAGCTCA
GTGAAGAAAATGATCCTCACATTTGAAAAGAGATCATATAAAAACCAAGAATTGCGGATTAAGTTTCCAGACAATCCAGAGAAGTTCATG
GAATCCGAGCTGGACCTAAATGACATCATTCAGGAGATGCACGTGGTGGCCACCATGCCAGACCTGTACCACCTTCTGGTGGAGCTGAAT
GCTGTACAGTCGCTTCTCGGCTTGCTCGGACACGATAATACAGATGTGTCCATAGCTGTGGTCGATTTGCTTCAGGAATTAACAGATATA
GACACCCTCCATGAGAGTGAAGAGGGAGCAGAAGTGCTCATCGATGCTCTGGTGGATGGGCAGGTGGTAGCACTGCTGGTACAGAATCTG
GAGCGCCTGGATGAGTCTGTGAAAGAGGAGGCAGATGGCGTCCACAACACTCTGGCTATTGTGGAAAACATGGCTGAGTTCCGGCCTGAG
ATGTGTACAGAGGGTGCCCAGCAGGGTCTTCTACAGTGGCTGTTGAAGAGGCTGAAGGCAAAGATGCCTTTTGATGCCAACAAACTGTAT
TGCAGTGAAGTGCTGGCCATATTGCTCCAGGACAATGATGAAAACAGGGAATTGCTTGGGGAGCTGGATGGAATCGATGTGCTTCTTCAG
CAGTTATCCGTGTTTAAAAGACACAATCCCAGCACGGCTGAGGAGCAGGAGATGATGGAGAATCTGTTTGATTCCCTCTGCTCCTGTCTA
ATGCTTAGTTCCAATCGTGAGCGCTTCCTGAAGGGCGAGGGTCTTCAGCTGATGAATCTCATGCTCAGGGAAAAGAAGATCTCCCGGAGC
AGTGCCCTGAAAGTGCTGGACCATGCCATGATTGGCCCCGAAGGCACAGACAACTGCCATAAGTTTGTTGACATTCTTGGCTTACGAACC
ATCTTTCCCCTCTTTATGAAATCTCCCAGGAAGATCAAGAAAGTGGGAACCACTGAGAAGGAACATGAAGGCTACGCCCAGGAGGAACAG
CTGAAAGAAGAGGAGGAAATAAAAGAAGAGGAGGAGGAGGAGGACAGCGGTTCAGTAGCTCAACTGCAGGGTGGCAATGACACAGGGACG
GACGAGGAGCTAGAAACGGGCCCAGAGCAAAAAGGCTGCTTCAGCTACCAGAACTCTCCAGGAAGTCATTTGTCCAATCAGGATGCCGAG
AACGAGTCTCTGCTGAGTGACGCCAGTGATCAGGTGTCGGACATCAAGAGTGTCTGCGGCAGAGATGCCTCAGACAAGAAAGCACACACT
CACGTCAGGCTTCCAAACGAAGCACACAATTGCATGGATAAAATGACCGCTGTCTACGCCAACATCCTGTCGGATTCCTACTGGTCAGGC
CTGGGCCTTGGCTTCAAGCTGTCCAATAGTGAGAGGAGGAACTGTGACACCCGAAACGGCAGCAACAAGAGTGATTTTGATTGGCACCAA
GACGCTCTGTCCAAAAGCCTGCAGCAGAACTTGCCTTCTCGGTCCGTCTCGAAACCCAGCCTGTTCAGCTCGGTGCAGTTGTACCGACAG
AGCAGCAAGATGTGCGGGACTGTGTTCACAGGGGCCAGCAGATTCCGATGCCGACAGTGCAGCGCGGCCTATGACACCCTAGTCGAGCTG
ACTGTGCACATGAATGAAACGGGCCACTATCAAGATGACAACCGCAAAAAGGACAAGCTCAGACCCACGAGCTATTCAAAGCCCAGGAAA
AGGGCTTTCCAGGATATGGACAAAGAGGATGCTCAAAAGGTTCTGAAATGTATGTTTTGTGGCGACTCCTTTGATTCCCTCCAAGATTTG
AGCGTCCACATGATTAAAACAAAACATTACCAAAAAGTGCCTTTGAAGGAGCCAGTCCCAACCATTTCCTCGAAAATGGTCACCCCGGCT
AAGAAACGCGTTTTTGATGTCAATCGGCCGTGTTCCCCCGATTCAACCACAGGATCTTTTGCAGATTCTTTTTCTTCTCAGAAGAACGCC
AACTTGCAGTTGTCCTCCAACAACCGCTATGGCTACCAAAATGGAGCCAGCTACACCTGGCAGTTTGAGGCCTGCAAGTCCCAGATCTTA
AAGTGCATGGAGTGTGGGAGCTCCCATGACACCTTGCAGCAGCTCACCACCCACATGATGGTCACAGGTCACTTTCTCAAGGTCACCAGC
TCTGCCTCCAAGAAAGGGAAGCAGCTGGTATTAGACCCGTTAGCAGTGGAGAAAATGCAGTCGTTGTCTGAGGCCCCAAACAGTGATTCT
CTGGCTCCCAAGCCATCCAGTAACTCAGCATCAGATTGTACAGCCTCTACAACTGAGTTAAAGAAAGAGAGTAAAAAAGAAAGGCCAGAG
GAAACCAGCAAGGATGAGAAAGTCGTGAAAAGCGAGGACTATGAAGATCCTCTACAAAAACCTTTAGACCCTACAATCAAATATCAATAC
CTAAGGGAGGAAGACTTGGAAGATGGCTCAAAGGGTGGAGGGGACATTTTGAAATCTTTGGAAAATACTGTCACCACAGCCATCAACAAA
GCCCAAAACGGGGCCCCCAGCTGGAGTGCCTACCCCAGCATCCACGCAGCCTACCAGCTGTCTGAGGGCACCAAGCCGCCTTTGCCTATG
GGATCCCAGGTACTGCAGATCCGGCCTAATCTCACCAACAAGCTGAGGCCCATTGCACCAAAGTGGAAAGTGATGCCACTGGTTTCTATG
CCCACACACCTGGCCCCTTACACTCAAGTCAAGAAAGAGTCAGAAGACAAAGATGAAGCGGTGAAGGAGTGTGGGAAAGAAAGTCCCCAC
GAAGAGGCCTCATCTTTCAGCCACAGTGAGGGCGATTCTTTCCGCAAAAGTGAAACACCTCCAGAAGCCAAAAAGACCGAGCTGGGTCCC
CTGAAGGAGGAGGAGAAGCTGATGAAAGAGGGCAGCGAGAAGGAGAAACCCCAGCCCCTGGAGCCCACATCTGCTCTGAGCAATGGGTGC
GCCCTCGCCAACCACGCCCCGGCCCTGCCATGCATCAACCCACTCAGCGCCCTGCAGTCCGTCCTGAACAATCACTTGGGCAAAGCCACG
GAGCCCTTGCGCTCACCTTCCTGCTCCAGCCCAAGTTCAAGCACAATTTCCATGTTCCACAAGTCGAATCTCAATGTCATGGACAAGCCG
GTCTTGAGTCCTGCCTCCACAAGGTCAGCCAGCGTGTCCAGGCGCTACCTGTTTGAGAACAGCGATCAGCCCATTGACCTGACCAAGTCC
AAAAGCAAGAAAGCCGAGTCCTCGCAAGCACAATCTTGTATGTCCCCACCTCAGAAGCACGCTCTGTCTGACATCGCCGACATGGTCAAA
GTCCTCCCCAAAGCCACCACCCCAAAGCCAGCCTCCTCCTCCAGGGTCCCCCCCATGAAGCTGGAAATGGATGTCAGGCGCTTTGAGGAT
GTCTCCAGTGAAGTCTCAACTTTGCATAAAAGAAAAGGCCGGCAGTCCAACTGGAATCCTCAGCATCTTCTGATTCTACAAGCCCAGTTT
GCCTCGAGCCTCTTCCAGACATCAGAGGGCAAATACCTGCTGTCTGATCTGGGCCCACAAGAGCGTATGCAAATCTCTAAGTTTACGGGA
CTCTCAATGACCACTATCAGTCACTGGCTGGCCAACGTCAAGTACCAGCTTAGGAAAACGGGCGGGACAAAATTTCTGAAAAACATGGAC
AAAGGCCACCCCATCTTTTATTGCAGTGACTGTGCCTCCCAGTTCAGAACCCCTTCTACCTACATCAGTCACTTAGAATCTCACCTGGGT
TTCCAAATGAAGGACATGACCCGCTTGTCAGTGGACCAGCAAAGCAAGGTGGAGCAAGAGATCTCCCGGGTATCGTCGGCTCAGAGGTCT
CCAGAAACAATAGCTGCCGAAGAGGACACAGACTCTAAATTCAAGTGTAAGTTGTGCTGTCGGACATTTGTGAGCAAACATGCGGTAAAA
CTCCACCTAAGCAAAACGCACAGCAAGTCACCCGAACACCATTCACAGTTTGTAACAGACGTGGATGAAGAATAGCTCTGCAGGACGAAT
GCCTTAGTTTCCACTTTCCAGCCTGGATCCCCTCACACTGAACCCTTCTTCGTTGCACCATCCTGCTTCTGACATTGAACTCATTGAACT
CCTCCTGACACCCTGGCTCTGAGAAGACTGCCAAAAAAAAAAAAAAAAAAAAATCACCCCAGCCATTTCTCTTCATCCTCACTAACAATT
TGGTAATGAAGTATTGATTTCCACTTCTCTGCTTATGGGCGGTATTAGATTTTCATTGATAAATTGCAATGGGGCTGTCTCGTCTCCACA
GTACCCTTTTCACTGTCACAAGAAAACAAAGTGCCACCGAAGAAAAGTAATGACTGAGAGCATTGATGTACTTATTTTGTCAGTTTGTAA
CAGGAAAGTGGGGGGGAGTCTAAGTCTTCATAGTCTAATGTCCAAGTGGGTTGCACTAGATGTAGACACTTGGAGGCTTACTTTTCATGG
TAATGTCCATTTCCTATTTATAACCCCTCTGGGAACGTTTGTCTAAAGGAAATGTTTCTGTTCAGTGTAACAATTACAGTTGCACCTGGA
TTGCCCAGTCCTGCCCCTGCACTAGGGGACCATTAATCACTGCAAAGTAGAAGAATTATTAAGTTAAACCAGAGTTTGAGCCAAGAAAAC
CCCTGAACAATGTTCATCTTCTGTGAAACTTGCTCAAATAGTTAAGCTTAACCATGTTGCTGCCAAAGACTTTTCCTATGCAGTGGTGGG
GCACCTTGATCATCATCATTATCTTGATTGGCTGAAAAAAAAATAGTTTTAAGCACACACCACTGTCTATGAGAACTGCAAATTGGGAGA
ATAGGTGAAATGCAGAATCTGAGAGAACGCGAGAAGATGAGATCATTACAGGGTGGAAAGTTCTGCAGCAGCCTTTTCTGGTAATCCCTT
TCTGCAGAACCTGATGTTTATGGGCTCTAAAACGCAGCTTAGCTTTAGAAGCAACAGAAAGCATGAAATAGGGTGTCCATTTTAAATGTG
TTCCTGCAACTTTTTTCATTAAAACTTTGAGGGCCCAATTTTAATTTGTGGAATATTCCCGTTAATAATGAGATCTAATTAAGACATCCA
TTAAAAGCCCGTTAAAGTTAATTTAACGTAAAAATTCCAATAGAACTGTATTAGATTTTCTCCATTAAATTAACGTTATGGATTTTTAAC
GGATGTCTTAATTATACGTTATTATTAACGGGAATACTGTATTACACAGATTAAAATCAGGTCCTAAGTCAACTTGGAAGAGCTAAGAGC
ATGTTTTAATATTAAAAGTCTTGCATACCTAGTGCACAGTTTGGAGACGCAAGGATAGATCTGTTTACTCTAGTTGAACATTTTCTATAC
AATTGAAAGCAACCTATAATAGATAAATCCATCATTGCATTTAAACAATGAATTTCCTTATTCTCAAAGGACAAATACGTCTGGATTATG
TGGTAAATTGCTACTCAGCTATGGTGAAATATTTATACTATTCTAGGCACAACACTAGGAACTAGGTGATTCTGAAACAAAAGGAATATT
TTCTGTTGTTGCTTTAATTACCAAGGTTATTTTTTTTTAATCTCAACACTGACAAAATGAAACCAAATATCTCTTCCTCACCATTTCTCA
AGGAGGCTGCCTGTTGGAATTGTTTTGGAAATTTTGACATGATCCCTAAATTCAACATTGGGATTAAAAAAAAAAAAAAACTTCTTATTT
ACCTCCTAGGGAAAGTGTTGCCCTTATGCCACATATAATAGCAAATTGCTTTTTTTATGGCATGCATAACCTAGATGGGAAAAAATATGG
CGCTTCGGGGAAGGAGGGAAAAAGTAAATGAAGTTCCAGGAATGTCATTCTGAAGTAATGAGGCATGGACAGAAAATATACCCCTCACAT
CATCGGATTGAGATGGCAGTCGAAATAGCTTCATTGAAGTGTCAGCACTCATCCATCAATCAATCACCCACAAGGAAAAATAGCAACAGT
ACAACGGGGTGGCTTTTATGGGATTTACTCATGGGCATAGGGAATAGCGGCTCAAATGTAGTTCTGACATGAAAAGCAAGGTGCTGATAT
TATTTTTTATGATGGGAGGATCATAAAGTGAATTGAGAACAGTGAGGTCTGTCTTTGCTTAACCTATTCAACCAGAAATGAATGGAGCTC
GACTGGAAAGGAACAGTCTTCAGATGGGTTAAGATTGAAGGGTGGACTGGACTCTACTGAGCACCGTCCTTCAACAAGGAAATTCTATTA
AAGGAAAATCAATGCATTAGTATTGGGGTTCTCGTAGCTGTTAAAAATTGTCTGCTCCAATCCAGGGTTATTAGGCCAAAGTTACATAAT
TCAGATCTCACTGCAACCATCCAAAAGTGGATTCTCGAGCCCTTGCTCCAATGGGGGGAGGAGATCAATACAATTCCCAATTCCATGGAA
ATTGTTTCCCTTCTAAGGAAGAAAAAATAAATCATCTGCTTCAACATATAATCGATATGGTTTTGTTAGCGTAATTTCTATGGTGGGTGG
GGTGGGAGGTGAGAGAAAAAAATATTGATAAATTTGGTAAGACAGGTGAATTGCCGCCTGGCAACCGTGCATGTCACTGCCGAGGGATGG
CTGCTAAGGTTCACCTTAGAAAACAAGATCTGGGCTGGCACTGGGGCATACATCACCACTCAGCATATTCCTAGAGGCCAGGCCTGTCTT
CACTCAGCCAGCCCTCTGAGGCTTCTAGAAACTTCTTTCTGGAGGAAAAAAACTAAATAACATAAACTCAGGAGAATGTCTTTACCCACC
TTCATACCACTGCTTTCTTTTTGCTGAATAAAACACAGTTCTGATAAGTAAGAACTTTAGAATTGGAAAGGAGGCTGACATGCAAATATA
ATGCAAATTACCCTCAAGTATCGCCATTCTTCCACCACCTCTTGGTACCAGTGAGAGCGAGAGATTGCCTTTTCTTCCCCATCCCTCCTT
CCAGCTAAGACCACCAACCAGCTGCAAATTGAGATGTCCATTTAAAAATTTATATGTCAATATTTAAATGTTACATATTTGGCCCTATTT
TGTAGTTCAGCAAATCCTCCAAATACACAGCATGTTACAAGGCACTGGTGGCACAGGGCACAACAGGAAATGATATTTATTTAGCAAATT
CATTTAACAAATATTATTGGGCACCTGTTATGTGAGACACTGTCCTAGGCACTGTGGGATAACAACAGCAAACACTTCACACAACAGCCT
GGCCTTCCTGTGTTTTACAACAGCTCCTAAAGATAGCTGATATCAAGACATTTGAGGGACACAGTTCATGTAGAATCAAAATATTAGTAT
TTCAGAATAAGGATTTTTTTTCTGAAAAGCATACAGAGAGGAAACAGCTTAAAAATAGGTCAAGACCTAAAAACAGAATATAATCACGGA
ATAAACTGGATAACCCAGACAGTCCCCACAGAATTTCTTTCAGGTCACAGATTTCTTAAAACTCACCCCCAAAATGTGCCTGCTTGGTTG
TTTGAATCTTGCATAATTAATGTCACAGGCGCAAGCCGCTGAACTTAGTTGAGATGCAGAAAACAAACAAATGCAATGACATATCTGAGA
AGCATTTATGTAACTCCGGTTAAGTGGTGAGGAGGGGTGTGTGAAGACAGTGTGCATGCATGAGTGTGTATTCATATATATGTGTATACA
TATGAATTTCACTGTTATTTTCCAGGGTCTATGGACAATGTGGCAGTAAGAGTCTATGATGTTCTGAAACTTTTCACAGTAAATCCAAAG
ATTACAGACCTTACAAGGTGCTTGCATTCTGTTGCTTTTCCATCTGTCACTTCTCAGGTTATTTGACTGTGTTCAAACCTTCTTTTCTTT
TTCATTGAGTTTCATTTTTTAAGCTTGTTAAATGCTTTTGTTTAAAAAAAAAAAAAAAACCCCAAATGTCATTTTTCACATTATCCTCTC
TTCTCTGCAACAAGGATAGTAAGATGTAGATGAATGCAAAAATAATAACAACAATAAGGAAATATATTAAAGCTTTAAAATATGCACATA
TGTAGTTCTAAAGAGCAATAACGGTAGTATCTATTTCGAACATGCATTAGGCAAAAAAGAAATCAAAACTGAAATTTTCGTGTATTTTTC
CCCTTGTAAGATGTTCAAATGCTAACTTCATTTTCTCCTTTCCTCTATGTGGCACTTTCTCAAAATATCTATGAAATACTTTTAGACAAA
GATTGAGCTGGAGAAAGAGATACAAATTTCCATCCCCCCAGACAGAGAGACATATTTCCATTGTAGGAAGGCATTAAACATTTTGAAACT
TGTGAATCATCTTTAGAATTTCTACTGGGGAATTTTACTTCTTCATCCAAAGTAAAAGCCACTTATCTCCTTTGGTTCCCAGTGACAGAT
TCAGAGGCATACGCAGATATACAATTTTCAGGCTCTAGTTAATCTTCTTCCAATAGTTACGAACAATGGGCTAACAGGCGTGGGTGTTTC
TCCAAAAATTATTCATGCACAAGGCAGCCCAAAGCTTCAGGGAAAACTAGAAATGTGTTATGGATTAGAATAGGACTGTTTTAAAATGCT
AGTACCAGGTGGAACGCTATTTCTGCAACAGGACTCTGTCCATTTCCTTTGGAACAATATATTCCAAGTAAAATGGCTCTTCCAAGGAAT
GACACCTTTACTTGACACCCTTCGGCATACAAATGATTTTACCAATAGCCATGATTATTATTAAGGCCTTTTAAAATACAGGCTGTTTGA
AAAAAGACAGATTAAATATTCACAGCCTTTGTATCATGGTTATTTGCTTAAAACAGCTTTTAGAAGTACAAGTAATAACTTTTTGATAAG
AAACCCCAGGAGAAACTTTTTGGTAAGAAACCTCAAAAAATTTGAACAAAGGCATTACAAAAAAAAAAAAAAAACTAACCACTCCATTCA
ACTCTCTCAGAAAATAAATTTCAATGTGTTCAATGAATTGTCTTGAACCTGAAACCTGCATTTAGATATCAGTCCCCTGCCAATAGCTAA
TATTAACAGAATTTGAACAATCATACAATTATGTCTCAAATGTGAAGACTTTGTACAGTAATATTTTCACTTTCTAAATGACCCATATAA
CATTCAGGAATTATAGATGTGTATGTATATTTTTTAAGTACAGAAAGTTCAGCCAGTCTTCAGAGAAGTAAAAGTGATGTCTATTGTGCA
TTGAAGTAAATATTACAAACATTCCAGTTTCGCAATACAATACTTGAGCTTTCGAACACCTCAGACACTAGAATGTGTAATGCGAGTCAA
AAAAGCTGACATACAAAACAATTCCCATTTGGCTCAGGGTTCCTAAATGTCACAATATCTTGGGTAAAATATACTTTTTGATTTCCTGAT
GATGTCCTTCTAATCCCTTCTGACTTTGATTCCTAACAGCCAGGCACTGTTGACATGAATCATTAACTTCCAAACCCCTTTAAAATCAAG
AAGCTAGGTGATCATACAGTCATTTCAATGGCCAACCAGTTCTTGCTCTACAGAGCTTTTACACCTTTTTGGGAAACCTGATATCAAACA
CATTTATGTTATATATTTGCTCCCTTGCATTAATTCTAGATTTTTTTTTAATTTCTTTTAGAAAGGGCAGGGGGGAAGTGGGTCAGAGCA
AGGTTCAAGAATCACATTCATCCTTGCTCTAAAGTGTTTACTTGCCAGCAAAGAAAGGCAAACACATTTTTATATTCAGAAAGCAGACCG
GTCATTTTCAAAGAAAAATGACTGCAACCATGCCTGTAGAATGTTTCTGTGCAAGCGCACTAATTTTCTATCACCTGCATGCTGTATATA
ATACATTTGCCTGTATACTAGGAAGAAAAACCAGGCTGTTTTCCCTGAGTACAATGCAGCTTGGATGGCTGGGAGCGTAAGCCTTCCGTG
CATTTTTATAGTGTACATATTTGTATATACTAACTATATCGCCATGTATGAACACAGATTTTGTTATATTTGCTTGTTTCTGTTTCCTAC
CAAACTGGCCCACAATGGGGATTCTTTTGTATAGAAAAAATATGCTTGTAATTTTTTCCTGGTCATTCTCTTTCAATAGCTTATGAAAGA
ATTAGATCTGAGTTTACAAAGAAACTATAAGAACCAAGTTTGTCTGTCTGCATGAGTCCCGTCCAATTGCTGGATCTAGGGAGGAACCAA
CTTCCTAATTCAGAGTTTTCCTTTTAAAGGCATGCTTTACCCCCATGGGAAAACTGCACACTCATCCATGTAGAATTATTCTCTTTGTAT
TTTATCTAATAGTGCCTGAAAATTTTTTTAATGTCTTCTTAGAAGAAGAATTCATAATTGTCAAAATTTGAAACATTAGCTTAATTTTGT
TTTTATGACCTCAAGATTCTTCTCCTTATTTATTCGGTTGCTGTTGTAATGGGGCCCCAGGCCATTCCTGACATCGGCGTGTTCTTCTTC
TGCATTAAGGATGTTTTTGAAATTACAGAGATTATTGAGCCAACAGGCTGTTTTAATCAAAACCATGTTTCACTTCTTTTTGATGATTAT
AAATTGTCCTTGCAATGAAAAAAAAAAAAGAACTTTTCTGCTAGGAAGATTATACCACCCTGTGGCCAAACAGATTCATCACAGATAGGC
ATCTATGCCCATTTCTCTGGGATCTGGAAAATTCTTCCCTTGGCTGACCCCAATTTCTTTTACTCCCCATTATCCTGAATATTAGCTTTC
AATGCAGTCACTATTTGACATTTCCAAAGGCTTTGCCGCATTGTCACTGCCCAAAGACAAACAACCACTGGAAATGATGGCTTTCCTGCT
TGAAACGAAGGGGGCCAGGTGCAGTGGCTCAAGCCTGTAACCCCTGCACTTTGGAAGGCTGAGGCAGGCGGATCACTTGAGGTCAGGAGT
TTCAGACCAACCTGGCCAACATGGCAAAACCTCGTCTCTACTAAAAATACAAAAAACATTAGCAGGGCATGGTGGTGCGTGCCTGTAGTC
CCAGCTACTTGGGAGGCTGAGGCAAGAGAATTGCTTGAGCCCGGGAGGCGAAGGTTGCAGTGAGCTGAGATGGTGCCACTGCACTCCAGC
CTGGGCAACAGAGCAAGACTGTGTCTCAAAAAAAAAAAAAAGAATGGATTTTCAGAAAAAGTGCTCCCTTTCCTGTCCTGTGGTGCCACC
ATCCTGTCCTCCTTCGTAATCATGAACAATCTGATCTTGAACTCCCACATAACTTAAATCAGGCAAAAAGAAACATTCACAGCGTCCCCT
TGCTGAATAAAAATGACTTTGTTTGGAGGCACTTAAGATGTATGCCTGTGTGTGGTGCCGCAGCATTGAAATTATCTGTAGAAGGGGAAT
TTTTTTTAAAAATACAATTTTATCACTAGAAATAAATTCCGATGGTGGAAACGAAGAAAACCCTTAAATTATATCACAAAAGCCATTATT
TTTTGCATCCAAAGAGTTTTTTTTTTTAAGGAAAATCATTCTACTTTGAGAACTGTAATTAAAGCCCTAAATAACAGACACTACTTTGTT
GAGCTATTGTGAAAAAAAAACAACACATTCGCCAAGGTTATATGGAGCCCCTGATTTCCATCAAAAAGGTTTCTATAAGTATATTATTTA
CATTTTTATACATGATAACTCTTGCCTTTGTGTTGAAAAAAAAAAAGTCTCTTTTTTTTCCCCCACTCAGCAGTTATTGGAAATAGACTG
TTCCCATCTGAAACCGTATCGTAATTTGCATCAGGAAACCCAACTGCTGACATTGAGGACCTGGGTGTGTTCAATTATGATTTTGCTGGA
GGCTGTCCCTCATTTTAATGCTGCAGCTATTGAACCACCTTCCTGAAACCTAGCTGATACGGAATAGCAGAGACATGCCTCTCAACACCA
TTAGCTTTGCAAATGGCTTCATTTCAGTCAACGTCGACTTCTGCTTTGGCCAATTGAAAAATGAAAATTAAAGGAGAGAAGAAAAAAAAC
ACAGATGCACTTAAAACATGAAAAGAATTATTTATATGATAAAAATATATTTAGCTTTTCAAAGCACAAGACTGAATAGAAGTGCTCTTT

>20353_20353_1_CTNNBL1-TSHZ2_CTNNBL1_chr20_36431450_ENST00000361383_TSHZ2_chr20_51870038_ENST00000371497_length(amino acids)=1425AA_BP=404
MDVGELLSYQPNRGTKRPRDDEEEEQKMRRKQTGTRERGRYREEEMTVVEEADDDKKRLLQIIDRDGEEEEEEEEPLDESSVKKMILTFE
KRSYKNQELRIKFPDNPEKFMESELDLNDIIQEMHVVATMPDLYHLLVELNAVQSLLGLLGHDNTDVSIAVVDLLQELTDIDTLHESEEG
AEVLIDALVDGQVVALLVQNLERLDESVKEEADGVHNTLAIVENMAEFRPEMCTEGAQQGLLQWLLKRLKAKMPFDANKLYCSEVLAILL
QDNDENRELLGELDGIDVLLQQLSVFKRHNPSTAEEQEMMENLFDSLCSCLMLSSNRERFLKGEGLQLMNLMLREKKISRSSALKVLDHA
MIGPEGTDNCHKFVDILGLRTIFPLFMKSPRKIKKVGTTEKEHEGYAQEEQLKEEEEIKEEEEEEDSGSVAQLQGGNDTGTDEELETGPE
QKGCFSYQNSPGSHLSNQDAENESLLSDASDQVSDIKSVCGRDASDKKAHTHVRLPNEAHNCMDKMTAVYANILSDSYWSGLGLGFKLSN
SERRNCDTRNGSNKSDFDWHQDALSKSLQQNLPSRSVSKPSLFSSVQLYRQSSKMCGTVFTGASRFRCRQCSAAYDTLVELTVHMNETGH
YQDDNRKKDKLRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNR
PCSPDSTTGSFADSFSSQKNANLQLSSNNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQL
VLDPLAVEKMQSLSEAPNSDSLAPKPSSNSASDCTASTTELKKESKKERPEETSKDEKVVKSEDYEDPLQKPLDPTIKYQYLREEDLEDG
SKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPPLPMGSQVLQIRPNLTNKLRPIAPKWKVMPLVSMPTHLAPYTQ
VKKESEDKDEAVKECGKESPHEEASSFSHSEGDSFRKSETPPEAKKTELGPLKEEEKLMKEGSEKEKPQPLEPTSALSNGCALANHAPAL
PCINPLSALQSVLNNHLGKATEPLRSPSCSSPSSSTISMFHKSNLNVMDKPVLSPASTRSASVSRRYLFENSDQPIDLTKSKSKKAESSQ
AQSCMSPPQKHALSDIADMVKVLPKATTPKPASSSRVPPMKLEMDVRRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSE
GKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQMKDMTRL

--------------------------------------------------------------
>20353_20353_2_CTNNBL1-TSHZ2_CTNNBL1_chr20_36431450_ENST00000361383_TSHZ2_chr20_51870038_ENST00000603338_length(transcript)=4739nt_BP=1330nt
ATTGGCTCTGCGGCTCCGCTCGCCGCACTTTACGGCAGTGTGGCTGGAGCCGCGGCTGACGGGCCCGCGGTCTGGGCGTGAGTGCAGGGA
AGTGGAGTATTTGCTGGGCCGGGTACCATGGACGTGGGCGAACTTCTGAGCTACCAGCCCAATAGGGGCACAAAACGTCCCCGGGATGAT
GAAGAGGAGGAGCAGAAGATGCGTCGGAAACAAACTGGTACTCGAGAACGCGGCCGCTATCGGGAAGAAGAAATGACTGTGGTGGAGGAA
GCGGATGATGACAAAAAAAGGCTGCTGCAGATTATTGACAGAGATGGGGAAGAGGAAGAGGAAGAGGAGGAGCCATTGGATGAAAGCTCA
GTGAAGAAAATGATCCTCACATTTGAAAAGAGATCATATAAAAACCAAGAATTGCGGATTAAGTTTCCAGACAATCCAGAGAAGTTCATG
GAATCCGAGCTGGACCTAAATGACATCATTCAGGAGATGCACGTGGTGGCCACCATGCCAGACCTGTACCACCTTCTGGTGGAGCTGAAT
GCTGTACAGTCGCTTCTCGGCTTGCTCGGACACGATAATACAGATGTGTCCATAGCTGTGGTCGATTTGCTTCAGGAATTAACAGATATA
GACACCCTCCATGAGAGTGAAGAGGGAGCAGAAGTGCTCATCGATGCTCTGGTGGATGGGCAGGTGGTAGCACTGCTGGTACAGAATCTG
GAGCGCCTGGATGAGTCTGTGAAAGAGGAGGCAGATGGCGTCCACAACACTCTGGCTATTGTGGAAAACATGGCTGAGTTCCGGCCTGAG
ATGTGTACAGAGGGTGCCCAGCAGGGTCTTCTACAGTGGCTGTTGAAGAGGCTGAAGGCAAAGATGCCTTTTGATGCCAACAAACTGTAT
TGCAGTGAAGTGCTGGCCATATTGCTCCAGGACAATGATGAAAACAGGGAATTGCTTGGGGAGCTGGATGGAATCGATGTGCTTCTTCAG
CAGTTATCCGTGTTTAAAAGACACAATCCCAGCACGGCTGAGGAGCAGGAGATGATGGAGAATCTGTTTGATTCCCTCTGCTCCTGTCTA
ATGCTTAGTTCCAATCGTGAGCGCTTCCTGAAGGGCGAGGGTCTTCAGCTGATGAATCTCATGCTCAGGGAAAAGAAGATCTCCCGGAGC
AGTGCCCTGAAAGTGCTGGACCATGCCATGATTGGCCCCGAAGGCACAGACAACTGCCATAAGTTTGTTGACATTCTTGGCTTACGAACC
ATCTTTCCCCTCTTTATGAAATCTCCCAGGAAGATCAAGAAAGTGGGAACCACTGAGAAGGAACATGAAGGCTACGCCCAGGAGGAACAG
CTGAAAGAAGAGGAGGAAATAAAAGAAGAGGAGGAGGAGGAGGACAGCGGTTCAGTAGCTCAACTGCAGGGTGGCAATGACACAGGGACG
GACGAGGAGCTAGAAACGGGCCCAGAGCAAAAAGGCTGCTTCAGCTACCAGAACTCTCCAGGAAGTCATTTGTCCAATCAGGATGCCGAG
AACGAGTCTCTGCTGAGTGACGCCAGTGATCAGGTGTCGGACATCAAGAGTGTCTGCGGCAGAGATGCCTCAGACAAGAAAGCACACACT
CACGTCAGGCTTCCAAACGAAGCACACAATTGCATGGATAAAATGACCGCTGTCTACGCCAACATCCTGTCGGATTCCTACTGGTCAGGC
CTGGGCCTTGGCTTCAAGCTGTCCAATAGTGAGAGGAGGAACTGTGACACCCGAAACGGCAGCAACAAGAGTGATTTTGATTGGCACCAA
GACGCTCTGTCCAAAAGCCTGCAGCAGAACTTGCCTTCTCGGTCCGTCTCGAAACCCAGCCTGTTCAGCTCGGTGCAGTTGTACCGACAG
AGCAGCAAGATGTGCGGGACTGTGTTCACAGGGGCCAGCAGATTCCGATGCCGACAGTGCAGCGCGGCCTATGACACCCTAGTCGAGCTG
ACTGTGCACATGAATGAAACGGGCCACTATCAAGATGACAACCGCAAAAAGGACAAGCTCAGACCCACGAGCTATTCAAAGCCCAGGAAA
AGGGCTTTCCAGGATATGGACAAAGAGGATGCTCAAAAGGTTCTGAAATGTATGTTTTGTGGCGACTCCTTTGATTCCCTCCAAGATTTG
AGCGTCCACATGATTAAAACAAAACATTACCAAAAAGTGCCTTTGAAGGAGCCAGTCCCAACCATTTCCTCGAAAATGGTCACCCCGGCT
AAGAAACGCGTTTTTGATGTCAATCGGCCGTGTTCCCCCGATTCAACCACAGGATCTTTTGCAGATTCTTTTTCTTCTCAGAAGAACGCC
AACTTGCAGTTGTCCTCCAACAACCGCTATGGCTACCAAAATGGAGCCAGCTACACCTGGCAGTTTGAGGCCTGCAAGTCCCAGATCTTA
AAGTGCATGGAGTGTGGGAGCTCCCATGACACCTTGCAGCAGCTCACCACCCACATGATGGTCACAGGTCACTTTCTCAAGGTCACCAGC
TCTGCCTCCAAGAAAGGGAAGCAGCTGGTATTAGACCCGTTAGCAGTGGAGAAAATGCAGTCGTTGTCTGAGGCCCCAAACAGTGATTCT
CTGGCTCCCAAGCCATCCAGTAACTCAGCATCAGATTGTACAGCCTCTACAACTGAGTTAAAGAAAGAGAGTAAAAAAGAAAGGCCAGAG
GAAACCAGCAAGGATGAGAAAGTCGTGAAAAGCGAGGACTATGAAGATCCTCTACAAAAACCTTTAGACCCTACAATCAAATATCAATAC
CTAAGGGAGGAAGACTTGGAAGATGGCTCAAAGGGTGGAGGGGACATTTTGAAATCTTTGGAAAATACTGTCACCACAGCCATCAACAAA
GCCCAAAACGGGGCCCCCAGCTGGAGTGCCTACCCCAGCATCCACGCAGCCTACCAGCTGTCTGAGGGCACCAAGCCGCCTTTGCCTATG
GGATCCCAGGTACTGCAGATCCGGCCTAATCTCACCAACAAGCTGAGGCCCATTGCACCAAAGTGGAAAGTGATGCCACTGGTTTCTATG
CCCACACACCTGGCCCCTTACACTCAAGTCAAGAAAGAGTCAGAAGACAAAGATGAAGCGGTGAAGGAGTGTGGGAAAGAAAGTCCCCAC
GAAGAGGCCTCATCTTTCAGCCACAGTGAGGGCGATTCTTTCCGCAAAAGTGAAACACCTCCAGAAGCCAAAAAGACCGAGCTGGGTCCC
CTGAAGGAGGAGGAGAAGCTGATGAAAGAGGGCAGCGAGAAGGAGAAACCCCAGCCCCTGGAGCCCACATCTGCTCTGAGCAATGGGTGC
GCCCTCGCCAACCACGCCCCGGCCCTGCCATGCATCAACCCACTCAGCGCCCTGCAGTCCGTCCTGAACAATCACTTGGGCAAAGCCACG
GAGCCCTTGCGCTCACCTTCCTGCTCCAGCCCAAGTTCAAGCACAATTTCCATGTTCCACAAGTCGAATCTCAATGTCATGGACAAGCCG
GTCTTGAGTCCTGCCTCCACAAGGTCAGCCAGCGTGTCCAGGCGCTACCTGTTTGAGAACAGCGATCAGCCCATTGACCTGACCAAGTCC
AAAAGCAAGAAAGCCGAGTCCTCGCAAGCACAATCTTGTATGTCCCCACCTCAGAAGCACGCTCTGTCTGACATCGCCGACATGGTCAAA
GTCCTCCCCAAAGCCACCACCCCAAAGCCAGCCTCCTCCTCCAGGGTCCCCCCCATGAAGCTGGAAATGGATGTCAGGCGCTTTGAGGAT
GTCTCCAGTGAAGTCTCAACTTTGCATAAAAGAAAAGGCCGGCAGTCCAACTGGAATCCTCAGCATCTTCTGATTCTACAAGCCCAGTTT
GCCTCGAGCCTCTTCCAGACATCAGAGGGCAAATACCTGCTGTCTGATCTGGGCCCACAAGAGCGTATGCAAATCTCTAAGTTTACGGGA
CTCTCAATGACCACTATCAGTCACTGGCTGGCCAACGTCAAGTACCAGCTTAGGAAAACGGGCGGGACAAAATTTCTGAAAAACATGGAC
AAAGGCCACCCCATCTTTTATTGCAGTGACTGTGCCTCCCAGTTCAGAACCCCTTCTACCTACATCAGTCACTTAGAATCTCACCTGGGT
TTCCAAATGAAGGACATGACCCGCTTGTCAGTGGACCAGCAAAGCAAGGTGGAGCAAGAGATCTCCCGGGTATCGTCGGCTCAGAGGTCT
CCAGAAACAATAGCTGCCGAAGAGGACACAGACTCTAAATTCAAGTGTAAGTTGTGCTGTCGGACATTTGTGAGCAAACATGCGGTAAAA
CTCCACCTAAGCAAAACGCACAGCAAGTCACCCGAACACCATTCACAGTTTGTAACAGACGTGGATGAAGAATAGCTCTGCAGGACGAAT
GCCTTAGTTTCCACTTTCCAGCCTGGATCCCCTCACACTGAACCCTTCTTCGTTGCACCATCCTGCTTCTGACATTGAACTCATTGAACT
CCTCCTGACACCCTGGCTCTGAGAAGACTGCCAAAAAAAAAAAAAAAAAAAAATCACCCCAGCCATTTCTCTTCATCCTCACTAACAATT
TGGTAATGAAGTATTGATTTCCACTTCTCTGCTTATGGGCGGTATTAGATTTTCATTGATAAATTGCAATGGGGCTGTCTCGTCTCCACA

>20353_20353_2_CTNNBL1-TSHZ2_CTNNBL1_chr20_36431450_ENST00000361383_TSHZ2_chr20_51870038_ENST00000603338_length(amino acids)=1425AA_BP=404
MDVGELLSYQPNRGTKRPRDDEEEEQKMRRKQTGTRERGRYREEEMTVVEEADDDKKRLLQIIDRDGEEEEEEEEPLDESSVKKMILTFE
KRSYKNQELRIKFPDNPEKFMESELDLNDIIQEMHVVATMPDLYHLLVELNAVQSLLGLLGHDNTDVSIAVVDLLQELTDIDTLHESEEG
AEVLIDALVDGQVVALLVQNLERLDESVKEEADGVHNTLAIVENMAEFRPEMCTEGAQQGLLQWLLKRLKAKMPFDANKLYCSEVLAILL
QDNDENRELLGELDGIDVLLQQLSVFKRHNPSTAEEQEMMENLFDSLCSCLMLSSNRERFLKGEGLQLMNLMLREKKISRSSALKVLDHA
MIGPEGTDNCHKFVDILGLRTIFPLFMKSPRKIKKVGTTEKEHEGYAQEEQLKEEEEIKEEEEEEDSGSVAQLQGGNDTGTDEELETGPE
QKGCFSYQNSPGSHLSNQDAENESLLSDASDQVSDIKSVCGRDASDKKAHTHVRLPNEAHNCMDKMTAVYANILSDSYWSGLGLGFKLSN
SERRNCDTRNGSNKSDFDWHQDALSKSLQQNLPSRSVSKPSLFSSVQLYRQSSKMCGTVFTGASRFRCRQCSAAYDTLVELTVHMNETGH
YQDDNRKKDKLRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNR
PCSPDSTTGSFADSFSSQKNANLQLSSNNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQL
VLDPLAVEKMQSLSEAPNSDSLAPKPSSNSASDCTASTTELKKESKKERPEETSKDEKVVKSEDYEDPLQKPLDPTIKYQYLREEDLEDG
SKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPPLPMGSQVLQIRPNLTNKLRPIAPKWKVMPLVSMPTHLAPYTQ
VKKESEDKDEAVKECGKESPHEEASSFSHSEGDSFRKSETPPEAKKTELGPLKEEEKLMKEGSEKEKPQPLEPTSALSNGCALANHAPAL
PCINPLSALQSVLNNHLGKATEPLRSPSCSSPSSSTISMFHKSNLNVMDKPVLSPASTRSASVSRRYLFENSDQPIDLTKSKSKKAESSQ
AQSCMSPPQKHALSDIADMVKVLPKATTPKPASSSRVPPMKLEMDVRRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSE
GKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQMKDMTRL

--------------------------------------------------------------
>20353_20353_3_CTNNBL1-TSHZ2_CTNNBL1_chr20_36431450_ENST00000373469_TSHZ2_chr20_51870038_ENST00000371497_length(transcript)=11795nt_BP=535nt
CGTGAAAAATTTGTCCTGGGGAAGGAAGCAAGACCCCTTAACATTTTTCTCATTTCTCCTATTTCCCCATAGGCAAAGATGCCTTTTGAT
GCCAACAAACTGTATTGCAGTGAAGTGCTGGCCATATTGCTCCAGGACAATGATGAAAACAGGGAATTGCTTGGGGAGCTGGATGGAATC
GATGTGCTTCTTCAGCAGTTATCCGTGTTTAAAAGACACAATCCCAGCACGGCTGAGGAGCAGGAGATGATGGAGAATCTGTTTGATTCC
CTCTGCTCCTGTCTAATGCTTAGTTCCAATCGTGAGCGCTTCCTGAAGGGCGAGGGTCTTCAGCTGATGAATCTCATGCTCAGGGAAAAG
AAGATCTCCCGGAGCAGTGCCCTGAAAGTGCTGGACCATGCCATGATTGGCCCCGAAGGCACAGACAACTGCCATAAGTTTGTTGACATT
CTTGGCTTACGAACCATCTTTCCCCTCTTTATGAAATCTCCCAGGAAGATCAAGAAAGTGGGAACCACTGAGAAGGAACATGAAGGCTAC
GCCCAGGAGGAACAGCTGAAAGAAGAGGAGGAAATAAAAGAAGAGGAGGAGGAGGAGGACAGCGGTTCAGTAGCTCAACTGCAGGGTGGC
AATGACACAGGGACGGACGAGGAGCTAGAAACGGGCCCAGAGCAAAAAGGCTGCTTCAGCTACCAGAACTCTCCAGGAAGTCATTTGTCC
AATCAGGATGCCGAGAACGAGTCTCTGCTGAGTGACGCCAGTGATCAGGTGTCGGACATCAAGAGTGTCTGCGGCAGAGATGCCTCAGAC
AAGAAAGCACACACTCACGTCAGGCTTCCAAACGAAGCACACAATTGCATGGATAAAATGACCGCTGTCTACGCCAACATCCTGTCGGAT
TCCTACTGGTCAGGCCTGGGCCTTGGCTTCAAGCTGTCCAATAGTGAGAGGAGGAACTGTGACACCCGAAACGGCAGCAACAAGAGTGAT
TTTGATTGGCACCAAGACGCTCTGTCCAAAAGCCTGCAGCAGAACTTGCCTTCTCGGTCCGTCTCGAAACCCAGCCTGTTCAGCTCGGTG
CAGTTGTACCGACAGAGCAGCAAGATGTGCGGGACTGTGTTCACAGGGGCCAGCAGATTCCGATGCCGACAGTGCAGCGCGGCCTATGAC
ACCCTAGTCGAGCTGACTGTGCACATGAATGAAACGGGCCACTATCAAGATGACAACCGCAAAAAGGACAAGCTCAGACCCACGAGCTAT
TCAAAGCCCAGGAAAAGGGCTTTCCAGGATATGGACAAAGAGGATGCTCAAAAGGTTCTGAAATGTATGTTTTGTGGCGACTCCTTTGAT
TCCCTCCAAGATTTGAGCGTCCACATGATTAAAACAAAACATTACCAAAAAGTGCCTTTGAAGGAGCCAGTCCCAACCATTTCCTCGAAA
ATGGTCACCCCGGCTAAGAAACGCGTTTTTGATGTCAATCGGCCGTGTTCCCCCGATTCAACCACAGGATCTTTTGCAGATTCTTTTTCT
TCTCAGAAGAACGCCAACTTGCAGTTGTCCTCCAACAACCGCTATGGCTACCAAAATGGAGCCAGCTACACCTGGCAGTTTGAGGCCTGC
AAGTCCCAGATCTTAAAGTGCATGGAGTGTGGGAGCTCCCATGACACCTTGCAGCAGCTCACCACCCACATGATGGTCACAGGTCACTTT
CTCAAGGTCACCAGCTCTGCCTCCAAGAAAGGGAAGCAGCTGGTATTAGACCCGTTAGCAGTGGAGAAAATGCAGTCGTTGTCTGAGGCC
CCAAACAGTGATTCTCTGGCTCCCAAGCCATCCAGTAACTCAGCATCAGATTGTACAGCCTCTACAACTGAGTTAAAGAAAGAGAGTAAA
AAAGAAAGGCCAGAGGAAACCAGCAAGGATGAGAAAGTCGTGAAAAGCGAGGACTATGAAGATCCTCTACAAAAACCTTTAGACCCTACA
ATCAAATATCAATACCTAAGGGAGGAAGACTTGGAAGATGGCTCAAAGGGTGGAGGGGACATTTTGAAATCTTTGGAAAATACTGTCACC
ACAGCCATCAACAAAGCCCAAAACGGGGCCCCCAGCTGGAGTGCCTACCCCAGCATCCACGCAGCCTACCAGCTGTCTGAGGGCACCAAG
CCGCCTTTGCCTATGGGATCCCAGGTACTGCAGATCCGGCCTAATCTCACCAACAAGCTGAGGCCCATTGCACCAAAGTGGAAAGTGATG
CCACTGGTTTCTATGCCCACACACCTGGCCCCTTACACTCAAGTCAAGAAAGAGTCAGAAGACAAAGATGAAGCGGTGAAGGAGTGTGGG
AAAGAAAGTCCCCACGAAGAGGCCTCATCTTTCAGCCACAGTGAGGGCGATTCTTTCCGCAAAAGTGAAACACCTCCAGAAGCCAAAAAG
ACCGAGCTGGGTCCCCTGAAGGAGGAGGAGAAGCTGATGAAAGAGGGCAGCGAGAAGGAGAAACCCCAGCCCCTGGAGCCCACATCTGCT
CTGAGCAATGGGTGCGCCCTCGCCAACCACGCCCCGGCCCTGCCATGCATCAACCCACTCAGCGCCCTGCAGTCCGTCCTGAACAATCAC
TTGGGCAAAGCCACGGAGCCCTTGCGCTCACCTTCCTGCTCCAGCCCAAGTTCAAGCACAATTTCCATGTTCCACAAGTCGAATCTCAAT
GTCATGGACAAGCCGGTCTTGAGTCCTGCCTCCACAAGGTCAGCCAGCGTGTCCAGGCGCTACCTGTTTGAGAACAGCGATCAGCCCATT
GACCTGACCAAGTCCAAAAGCAAGAAAGCCGAGTCCTCGCAAGCACAATCTTGTATGTCCCCACCTCAGAAGCACGCTCTGTCTGACATC
GCCGACATGGTCAAAGTCCTCCCCAAAGCCACCACCCCAAAGCCAGCCTCCTCCTCCAGGGTCCCCCCCATGAAGCTGGAAATGGATGTC
AGGCGCTTTGAGGATGTCTCCAGTGAAGTCTCAACTTTGCATAAAAGAAAAGGCCGGCAGTCCAACTGGAATCCTCAGCATCTTCTGATT
CTACAAGCCCAGTTTGCCTCGAGCCTCTTCCAGACATCAGAGGGCAAATACCTGCTGTCTGATCTGGGCCCACAAGAGCGTATGCAAATC
TCTAAGTTTACGGGACTCTCAATGACCACTATCAGTCACTGGCTGGCCAACGTCAAGTACCAGCTTAGGAAAACGGGCGGGACAAAATTT
CTGAAAAACATGGACAAAGGCCACCCCATCTTTTATTGCAGTGACTGTGCCTCCCAGTTCAGAACCCCTTCTACCTACATCAGTCACTTA
GAATCTCACCTGGGTTTCCAAATGAAGGACATGACCCGCTTGTCAGTGGACCAGCAAAGCAAGGTGGAGCAAGAGATCTCCCGGGTATCG
TCGGCTCAGAGGTCTCCAGAAACAATAGCTGCCGAAGAGGACACAGACTCTAAATTCAAGTGTAAGTTGTGCTGTCGGACATTTGTGAGC
AAACATGCGGTAAAACTCCACCTAAGCAAAACGCACAGCAAGTCACCCGAACACCATTCACAGTTTGTAACAGACGTGGATGAAGAATAG
CTCTGCAGGACGAATGCCTTAGTTTCCACTTTCCAGCCTGGATCCCCTCACACTGAACCCTTCTTCGTTGCACCATCCTGCTTCTGACAT
TGAACTCATTGAACTCCTCCTGACACCCTGGCTCTGAGAAGACTGCCAAAAAAAAAAAAAAAAAAAAATCACCCCAGCCATTTCTCTTCA
TCCTCACTAACAATTTGGTAATGAAGTATTGATTTCCACTTCTCTGCTTATGGGCGGTATTAGATTTTCATTGATAAATTGCAATGGGGC
TGTCTCGTCTCCACAGTACCCTTTTCACTGTCACAAGAAAACAAAGTGCCACCGAAGAAAAGTAATGACTGAGAGCATTGATGTACTTAT
TTTGTCAGTTTGTAACAGGAAAGTGGGGGGGAGTCTAAGTCTTCATAGTCTAATGTCCAAGTGGGTTGCACTAGATGTAGACACTTGGAG
GCTTACTTTTCATGGTAATGTCCATTTCCTATTTATAACCCCTCTGGGAACGTTTGTCTAAAGGAAATGTTTCTGTTCAGTGTAACAATT
ACAGTTGCACCTGGATTGCCCAGTCCTGCCCCTGCACTAGGGGACCATTAATCACTGCAAAGTAGAAGAATTATTAAGTTAAACCAGAGT
TTGAGCCAAGAAAACCCCTGAACAATGTTCATCTTCTGTGAAACTTGCTCAAATAGTTAAGCTTAACCATGTTGCTGCCAAAGACTTTTC
CTATGCAGTGGTGGGGCACCTTGATCATCATCATTATCTTGATTGGCTGAAAAAAAAATAGTTTTAAGCACACACCACTGTCTATGAGAA
CTGCAAATTGGGAGAATAGGTGAAATGCAGAATCTGAGAGAACGCGAGAAGATGAGATCATTACAGGGTGGAAAGTTCTGCAGCAGCCTT
TTCTGGTAATCCCTTTCTGCAGAACCTGATGTTTATGGGCTCTAAAACGCAGCTTAGCTTTAGAAGCAACAGAAAGCATGAAATAGGGTG
TCCATTTTAAATGTGTTCCTGCAACTTTTTTCATTAAAACTTTGAGGGCCCAATTTTAATTTGTGGAATATTCCCGTTAATAATGAGATC
TAATTAAGACATCCATTAAAAGCCCGTTAAAGTTAATTTAACGTAAAAATTCCAATAGAACTGTATTAGATTTTCTCCATTAAATTAACG
TTATGGATTTTTAACGGATGTCTTAATTATACGTTATTATTAACGGGAATACTGTATTACACAGATTAAAATCAGGTCCTAAGTCAACTT
GGAAGAGCTAAGAGCATGTTTTAATATTAAAAGTCTTGCATACCTAGTGCACAGTTTGGAGACGCAAGGATAGATCTGTTTACTCTAGTT
GAACATTTTCTATACAATTGAAAGCAACCTATAATAGATAAATCCATCATTGCATTTAAACAATGAATTTCCTTATTCTCAAAGGACAAA
TACGTCTGGATTATGTGGTAAATTGCTACTCAGCTATGGTGAAATATTTATACTATTCTAGGCACAACACTAGGAACTAGGTGATTCTGA
AACAAAAGGAATATTTTCTGTTGTTGCTTTAATTACCAAGGTTATTTTTTTTTAATCTCAACACTGACAAAATGAAACCAAATATCTCTT
CCTCACCATTTCTCAAGGAGGCTGCCTGTTGGAATTGTTTTGGAAATTTTGACATGATCCCTAAATTCAACATTGGGATTAAAAAAAAAA
AAAAACTTCTTATTTACCTCCTAGGGAAAGTGTTGCCCTTATGCCACATATAATAGCAAATTGCTTTTTTTATGGCATGCATAACCTAGA
TGGGAAAAAATATGGCGCTTCGGGGAAGGAGGGAAAAAGTAAATGAAGTTCCAGGAATGTCATTCTGAAGTAATGAGGCATGGACAGAAA
ATATACCCCTCACATCATCGGATTGAGATGGCAGTCGAAATAGCTTCATTGAAGTGTCAGCACTCATCCATCAATCAATCACCCACAAGG
AAAAATAGCAACAGTACAACGGGGTGGCTTTTATGGGATTTACTCATGGGCATAGGGAATAGCGGCTCAAATGTAGTTCTGACATGAAAA
GCAAGGTGCTGATATTATTTTTTATGATGGGAGGATCATAAAGTGAATTGAGAACAGTGAGGTCTGTCTTTGCTTAACCTATTCAACCAG
AAATGAATGGAGCTCGACTGGAAAGGAACAGTCTTCAGATGGGTTAAGATTGAAGGGTGGACTGGACTCTACTGAGCACCGTCCTTCAAC
AAGGAAATTCTATTAAAGGAAAATCAATGCATTAGTATTGGGGTTCTCGTAGCTGTTAAAAATTGTCTGCTCCAATCCAGGGTTATTAGG
CCAAAGTTACATAATTCAGATCTCACTGCAACCATCCAAAAGTGGATTCTCGAGCCCTTGCTCCAATGGGGGGAGGAGATCAATACAATT
CCCAATTCCATGGAAATTGTTTCCCTTCTAAGGAAGAAAAAATAAATCATCTGCTTCAACATATAATCGATATGGTTTTGTTAGCGTAAT
TTCTATGGTGGGTGGGGTGGGAGGTGAGAGAAAAAAATATTGATAAATTTGGTAAGACAGGTGAATTGCCGCCTGGCAACCGTGCATGTC
ACTGCCGAGGGATGGCTGCTAAGGTTCACCTTAGAAAACAAGATCTGGGCTGGCACTGGGGCATACATCACCACTCAGCATATTCCTAGA
GGCCAGGCCTGTCTTCACTCAGCCAGCCCTCTGAGGCTTCTAGAAACTTCTTTCTGGAGGAAAAAAACTAAATAACATAAACTCAGGAGA
ATGTCTTTACCCACCTTCATACCACTGCTTTCTTTTTGCTGAATAAAACACAGTTCTGATAAGTAAGAACTTTAGAATTGGAAAGGAGGC
TGACATGCAAATATAATGCAAATTACCCTCAAGTATCGCCATTCTTCCACCACCTCTTGGTACCAGTGAGAGCGAGAGATTGCCTTTTCT
TCCCCATCCCTCCTTCCAGCTAAGACCACCAACCAGCTGCAAATTGAGATGTCCATTTAAAAATTTATATGTCAATATTTAAATGTTACA
TATTTGGCCCTATTTTGTAGTTCAGCAAATCCTCCAAATACACAGCATGTTACAAGGCACTGGTGGCACAGGGCACAACAGGAAATGATA
TTTATTTAGCAAATTCATTTAACAAATATTATTGGGCACCTGTTATGTGAGACACTGTCCTAGGCACTGTGGGATAACAACAGCAAACAC
TTCACACAACAGCCTGGCCTTCCTGTGTTTTACAACAGCTCCTAAAGATAGCTGATATCAAGACATTTGAGGGACACAGTTCATGTAGAA
TCAAAATATTAGTATTTCAGAATAAGGATTTTTTTTCTGAAAAGCATACAGAGAGGAAACAGCTTAAAAATAGGTCAAGACCTAAAAACA
GAATATAATCACGGAATAAACTGGATAACCCAGACAGTCCCCACAGAATTTCTTTCAGGTCACAGATTTCTTAAAACTCACCCCCAAAAT
GTGCCTGCTTGGTTGTTTGAATCTTGCATAATTAATGTCACAGGCGCAAGCCGCTGAACTTAGTTGAGATGCAGAAAACAAACAAATGCA
ATGACATATCTGAGAAGCATTTATGTAACTCCGGTTAAGTGGTGAGGAGGGGTGTGTGAAGACAGTGTGCATGCATGAGTGTGTATTCAT
ATATATGTGTATACATATGAATTTCACTGTTATTTTCCAGGGTCTATGGACAATGTGGCAGTAAGAGTCTATGATGTTCTGAAACTTTTC
ACAGTAAATCCAAAGATTACAGACCTTACAAGGTGCTTGCATTCTGTTGCTTTTCCATCTGTCACTTCTCAGGTTATTTGACTGTGTTCA
AACCTTCTTTTCTTTTTCATTGAGTTTCATTTTTTAAGCTTGTTAAATGCTTTTGTTTAAAAAAAAAAAAAAAACCCCAAATGTCATTTT
TCACATTATCCTCTCTTCTCTGCAACAAGGATAGTAAGATGTAGATGAATGCAAAAATAATAACAACAATAAGGAAATATATTAAAGCTT
TAAAATATGCACATATGTAGTTCTAAAGAGCAATAACGGTAGTATCTATTTCGAACATGCATTAGGCAAAAAAGAAATCAAAACTGAAAT
TTTCGTGTATTTTTCCCCTTGTAAGATGTTCAAATGCTAACTTCATTTTCTCCTTTCCTCTATGTGGCACTTTCTCAAAATATCTATGAA
ATACTTTTAGACAAAGATTGAGCTGGAGAAAGAGATACAAATTTCCATCCCCCCAGACAGAGAGACATATTTCCATTGTAGGAAGGCATT
AAACATTTTGAAACTTGTGAATCATCTTTAGAATTTCTACTGGGGAATTTTACTTCTTCATCCAAAGTAAAAGCCACTTATCTCCTTTGG
TTCCCAGTGACAGATTCAGAGGCATACGCAGATATACAATTTTCAGGCTCTAGTTAATCTTCTTCCAATAGTTACGAACAATGGGCTAAC
AGGCGTGGGTGTTTCTCCAAAAATTATTCATGCACAAGGCAGCCCAAAGCTTCAGGGAAAACTAGAAATGTGTTATGGATTAGAATAGGA
CTGTTTTAAAATGCTAGTACCAGGTGGAACGCTATTTCTGCAACAGGACTCTGTCCATTTCCTTTGGAACAATATATTCCAAGTAAAATG
GCTCTTCCAAGGAATGACACCTTTACTTGACACCCTTCGGCATACAAATGATTTTACCAATAGCCATGATTATTATTAAGGCCTTTTAAA
ATACAGGCTGTTTGAAAAAAGACAGATTAAATATTCACAGCCTTTGTATCATGGTTATTTGCTTAAAACAGCTTTTAGAAGTACAAGTAA
TAACTTTTTGATAAGAAACCCCAGGAGAAACTTTTTGGTAAGAAACCTCAAAAAATTTGAACAAAGGCATTACAAAAAAAAAAAAAAAAC
TAACCACTCCATTCAACTCTCTCAGAAAATAAATTTCAATGTGTTCAATGAATTGTCTTGAACCTGAAACCTGCATTTAGATATCAGTCC
CCTGCCAATAGCTAATATTAACAGAATTTGAACAATCATACAATTATGTCTCAAATGTGAAGACTTTGTACAGTAATATTTTCACTTTCT
AAATGACCCATATAACATTCAGGAATTATAGATGTGTATGTATATTTTTTAAGTACAGAAAGTTCAGCCAGTCTTCAGAGAAGTAAAAGT
GATGTCTATTGTGCATTGAAGTAAATATTACAAACATTCCAGTTTCGCAATACAATACTTGAGCTTTCGAACACCTCAGACACTAGAATG
TGTAATGCGAGTCAAAAAAGCTGACATACAAAACAATTCCCATTTGGCTCAGGGTTCCTAAATGTCACAATATCTTGGGTAAAATATACT
TTTTGATTTCCTGATGATGTCCTTCTAATCCCTTCTGACTTTGATTCCTAACAGCCAGGCACTGTTGACATGAATCATTAACTTCCAAAC
CCCTTTAAAATCAAGAAGCTAGGTGATCATACAGTCATTTCAATGGCCAACCAGTTCTTGCTCTACAGAGCTTTTACACCTTTTTGGGAA
ACCTGATATCAAACACATTTATGTTATATATTTGCTCCCTTGCATTAATTCTAGATTTTTTTTTAATTTCTTTTAGAAAGGGCAGGGGGG
AAGTGGGTCAGAGCAAGGTTCAAGAATCACATTCATCCTTGCTCTAAAGTGTTTACTTGCCAGCAAAGAAAGGCAAACACATTTTTATAT
TCAGAAAGCAGACCGGTCATTTTCAAAGAAAAATGACTGCAACCATGCCTGTAGAATGTTTCTGTGCAAGCGCACTAATTTTCTATCACC
TGCATGCTGTATATAATACATTTGCCTGTATACTAGGAAGAAAAACCAGGCTGTTTTCCCTGAGTACAATGCAGCTTGGATGGCTGGGAG
CGTAAGCCTTCCGTGCATTTTTATAGTGTACATATTTGTATATACTAACTATATCGCCATGTATGAACACAGATTTTGTTATATTTGCTT
GTTTCTGTTTCCTACCAAACTGGCCCACAATGGGGATTCTTTTGTATAGAAAAAATATGCTTGTAATTTTTTCCTGGTCATTCTCTTTCA
ATAGCTTATGAAAGAATTAGATCTGAGTTTACAAAGAAACTATAAGAACCAAGTTTGTCTGTCTGCATGAGTCCCGTCCAATTGCTGGAT
CTAGGGAGGAACCAACTTCCTAATTCAGAGTTTTCCTTTTAAAGGCATGCTTTACCCCCATGGGAAAACTGCACACTCATCCATGTAGAA
TTATTCTCTTTGTATTTTATCTAATAGTGCCTGAAAATTTTTTTAATGTCTTCTTAGAAGAAGAATTCATAATTGTCAAAATTTGAAACA
TTAGCTTAATTTTGTTTTTATGACCTCAAGATTCTTCTCCTTATTTATTCGGTTGCTGTTGTAATGGGGCCCCAGGCCATTCCTGACATC
GGCGTGTTCTTCTTCTGCATTAAGGATGTTTTTGAAATTACAGAGATTATTGAGCCAACAGGCTGTTTTAATCAAAACCATGTTTCACTT
CTTTTTGATGATTATAAATTGTCCTTGCAATGAAAAAAAAAAAAGAACTTTTCTGCTAGGAAGATTATACCACCCTGTGGCCAAACAGAT
TCATCACAGATAGGCATCTATGCCCATTTCTCTGGGATCTGGAAAATTCTTCCCTTGGCTGACCCCAATTTCTTTTACTCCCCATTATCC
TGAATATTAGCTTTCAATGCAGTCACTATTTGACATTTCCAAAGGCTTTGCCGCATTGTCACTGCCCAAAGACAAACAACCACTGGAAAT
GATGGCTTTCCTGCTTGAAACGAAGGGGGCCAGGTGCAGTGGCTCAAGCCTGTAACCCCTGCACTTTGGAAGGCTGAGGCAGGCGGATCA
CTTGAGGTCAGGAGTTTCAGACCAACCTGGCCAACATGGCAAAACCTCGTCTCTACTAAAAATACAAAAAACATTAGCAGGGCATGGTGG
TGCGTGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAAGAGAATTGCTTGAGCCCGGGAGGCGAAGGTTGCAGTGAGCTGAGATGGTG
CCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTGTGTCTCAAAAAAAAAAAAAAGAATGGATTTTCAGAAAAAGTGCTCCCTTTCCTG
TCCTGTGGTGCCACCATCCTGTCCTCCTTCGTAATCATGAACAATCTGATCTTGAACTCCCACATAACTTAAATCAGGCAAAAAGAAACA
TTCACAGCGTCCCCTTGCTGAATAAAAATGACTTTGTTTGGAGGCACTTAAGATGTATGCCTGTGTGTGGTGCCGCAGCATTGAAATTAT
CTGTAGAAGGGGAATTTTTTTTAAAAATACAATTTTATCACTAGAAATAAATTCCGATGGTGGAAACGAAGAAAACCCTTAAATTATATC
ACAAAAGCCATTATTTTTTGCATCCAAAGAGTTTTTTTTTTTAAGGAAAATCATTCTACTTTGAGAACTGTAATTAAAGCCCTAAATAAC
AGACACTACTTTGTTGAGCTATTGTGAAAAAAAAACAACACATTCGCCAAGGTTATATGGAGCCCCTGATTTCCATCAAAAAGGTTTCTA
TAAGTATATTATTTACATTTTTATACATGATAACTCTTGCCTTTGTGTTGAAAAAAAAAAAGTCTCTTTTTTTTCCCCCACTCAGCAGTT
ATTGGAAATAGACTGTTCCCATCTGAAACCGTATCGTAATTTGCATCAGGAAACCCAACTGCTGACATTGAGGACCTGGGTGTGTTCAAT
TATGATTTTGCTGGAGGCTGTCCCTCATTTTAATGCTGCAGCTATTGAACCACCTTCCTGAAACCTAGCTGATACGGAATAGCAGAGACA
TGCCTCTCAACACCATTAGCTTTGCAAATGGCTTCATTTCAGTCAACGTCGACTTCTGCTTTGGCCAATTGAAAAATGAAAATTAAAGGA
GAGAAGAAAAAAAACACAGATGCACTTAAAACATGAAAAGAATTATTTATATGATAAAAATATATTTAGCTTTTCAAAGCACAAGACTGA
ATAGAAGTGCTCTTTTTATGCTTTCTGGAGATGTTACTGTTAAATGTCTTTCTACATCAGGCTTAATAAATCTGTAATGACATTTGATGG

>20353_20353_3_CTNNBL1-TSHZ2_CTNNBL1_chr20_36431450_ENST00000373469_TSHZ2_chr20_51870038_ENST00000371497_length(amino acids)=1173AA_BP=152
MPFDANKLYCSEVLAILLQDNDENRELLGELDGIDVLLQQLSVFKRHNPSTAEEQEMMENLFDSLCSCLMLSSNRERFLKGEGLQLMNLM
LREKKISRSSALKVLDHAMIGPEGTDNCHKFVDILGLRTIFPLFMKSPRKIKKVGTTEKEHEGYAQEEQLKEEEEIKEEEEEEDSGSVAQ
LQGGNDTGTDEELETGPEQKGCFSYQNSPGSHLSNQDAENESLLSDASDQVSDIKSVCGRDASDKKAHTHVRLPNEAHNCMDKMTAVYAN
ILSDSYWSGLGLGFKLSNSERRNCDTRNGSNKSDFDWHQDALSKSLQQNLPSRSVSKPSLFSSVQLYRQSSKMCGTVFTGASRFRCRQCS
AAYDTLVELTVHMNETGHYQDDNRKKDKLRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPT
ISSKMVTPAKKRVFDVNRPCSPDSTTGSFADSFSSQKNANLQLSSNNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMV
TGHFLKVTSSASKKGKQLVLDPLAVEKMQSLSEAPNSDSLAPKPSSNSASDCTASTTELKKESKKERPEETSKDEKVVKSEDYEDPLQKP
LDPTIKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPPLPMGSQVLQIRPNLTNKLRPIAPK
WKVMPLVSMPTHLAPYTQVKKESEDKDEAVKECGKESPHEEASSFSHSEGDSFRKSETPPEAKKTELGPLKEEEKLMKEGSEKEKPQPLE
PTSALSNGCALANHAPALPCINPLSALQSVLNNHLGKATEPLRSPSCSSPSSSTISMFHKSNLNVMDKPVLSPASTRSASVSRRYLFENS
DQPIDLTKSKSKKAESSQAQSCMSPPQKHALSDIADMVKVLPKATTPKPASSSRVPPMKLEMDVRRFEDVSSEVSTLHKRKGRQSNWNPQ
HLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTY
ISHLESHLGFQMKDMTRLSVDQQSKVEQEISRVSSAQRSPETIAAEEDTDSKFKCKLCCRTFVSKHAVKLHLSKTHSKSPEHHSQFVTDV

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>20353_20353_4_CTNNBL1-TSHZ2_CTNNBL1_chr20_36431450_ENST00000373469_TSHZ2_chr20_51870038_ENST00000603338_length(transcript)=3944nt_BP=535nt
CGTGAAAAATTTGTCCTGGGGAAGGAAGCAAGACCCCTTAACATTTTTCTCATTTCTCCTATTTCCCCATAGGCAAAGATGCCTTTTGAT
GCCAACAAACTGTATTGCAGTGAAGTGCTGGCCATATTGCTCCAGGACAATGATGAAAACAGGGAATTGCTTGGGGAGCTGGATGGAATC
GATGTGCTTCTTCAGCAGTTATCCGTGTTTAAAAGACACAATCCCAGCACGGCTGAGGAGCAGGAGATGATGGAGAATCTGTTTGATTCC
CTCTGCTCCTGTCTAATGCTTAGTTCCAATCGTGAGCGCTTCCTGAAGGGCGAGGGTCTTCAGCTGATGAATCTCATGCTCAGGGAAAAG
AAGATCTCCCGGAGCAGTGCCCTGAAAGTGCTGGACCATGCCATGATTGGCCCCGAAGGCACAGACAACTGCCATAAGTTTGTTGACATT
CTTGGCTTACGAACCATCTTTCCCCTCTTTATGAAATCTCCCAGGAAGATCAAGAAAGTGGGAACCACTGAGAAGGAACATGAAGGCTAC
GCCCAGGAGGAACAGCTGAAAGAAGAGGAGGAAATAAAAGAAGAGGAGGAGGAGGAGGACAGCGGTTCAGTAGCTCAACTGCAGGGTGGC
AATGACACAGGGACGGACGAGGAGCTAGAAACGGGCCCAGAGCAAAAAGGCTGCTTCAGCTACCAGAACTCTCCAGGAAGTCATTTGTCC
AATCAGGATGCCGAGAACGAGTCTCTGCTGAGTGACGCCAGTGATCAGGTGTCGGACATCAAGAGTGTCTGCGGCAGAGATGCCTCAGAC
AAGAAAGCACACACTCACGTCAGGCTTCCAAACGAAGCACACAATTGCATGGATAAAATGACCGCTGTCTACGCCAACATCCTGTCGGAT
TCCTACTGGTCAGGCCTGGGCCTTGGCTTCAAGCTGTCCAATAGTGAGAGGAGGAACTGTGACACCCGAAACGGCAGCAACAAGAGTGAT
TTTGATTGGCACCAAGACGCTCTGTCCAAAAGCCTGCAGCAGAACTTGCCTTCTCGGTCCGTCTCGAAACCCAGCCTGTTCAGCTCGGTG
CAGTTGTACCGACAGAGCAGCAAGATGTGCGGGACTGTGTTCACAGGGGCCAGCAGATTCCGATGCCGACAGTGCAGCGCGGCCTATGAC
ACCCTAGTCGAGCTGACTGTGCACATGAATGAAACGGGCCACTATCAAGATGACAACCGCAAAAAGGACAAGCTCAGACCCACGAGCTAT
TCAAAGCCCAGGAAAAGGGCTTTCCAGGATATGGACAAAGAGGATGCTCAAAAGGTTCTGAAATGTATGTTTTGTGGCGACTCCTTTGAT
TCCCTCCAAGATTTGAGCGTCCACATGATTAAAACAAAACATTACCAAAAAGTGCCTTTGAAGGAGCCAGTCCCAACCATTTCCTCGAAA
ATGGTCACCCCGGCTAAGAAACGCGTTTTTGATGTCAATCGGCCGTGTTCCCCCGATTCAACCACAGGATCTTTTGCAGATTCTTTTTCT
TCTCAGAAGAACGCCAACTTGCAGTTGTCCTCCAACAACCGCTATGGCTACCAAAATGGAGCCAGCTACACCTGGCAGTTTGAGGCCTGC
AAGTCCCAGATCTTAAAGTGCATGGAGTGTGGGAGCTCCCATGACACCTTGCAGCAGCTCACCACCCACATGATGGTCACAGGTCACTTT
CTCAAGGTCACCAGCTCTGCCTCCAAGAAAGGGAAGCAGCTGGTATTAGACCCGTTAGCAGTGGAGAAAATGCAGTCGTTGTCTGAGGCC
CCAAACAGTGATTCTCTGGCTCCCAAGCCATCCAGTAACTCAGCATCAGATTGTACAGCCTCTACAACTGAGTTAAAGAAAGAGAGTAAA
AAAGAAAGGCCAGAGGAAACCAGCAAGGATGAGAAAGTCGTGAAAAGCGAGGACTATGAAGATCCTCTACAAAAACCTTTAGACCCTACA
ATCAAATATCAATACCTAAGGGAGGAAGACTTGGAAGATGGCTCAAAGGGTGGAGGGGACATTTTGAAATCTTTGGAAAATACTGTCACC
ACAGCCATCAACAAAGCCCAAAACGGGGCCCCCAGCTGGAGTGCCTACCCCAGCATCCACGCAGCCTACCAGCTGTCTGAGGGCACCAAG
CCGCCTTTGCCTATGGGATCCCAGGTACTGCAGATCCGGCCTAATCTCACCAACAAGCTGAGGCCCATTGCACCAAAGTGGAAAGTGATG
CCACTGGTTTCTATGCCCACACACCTGGCCCCTTACACTCAAGTCAAGAAAGAGTCAGAAGACAAAGATGAAGCGGTGAAGGAGTGTGGG
AAAGAAAGTCCCCACGAAGAGGCCTCATCTTTCAGCCACAGTGAGGGCGATTCTTTCCGCAAAAGTGAAACACCTCCAGAAGCCAAAAAG
ACCGAGCTGGGTCCCCTGAAGGAGGAGGAGAAGCTGATGAAAGAGGGCAGCGAGAAGGAGAAACCCCAGCCCCTGGAGCCCACATCTGCT
CTGAGCAATGGGTGCGCCCTCGCCAACCACGCCCCGGCCCTGCCATGCATCAACCCACTCAGCGCCCTGCAGTCCGTCCTGAACAATCAC
TTGGGCAAAGCCACGGAGCCCTTGCGCTCACCTTCCTGCTCCAGCCCAAGTTCAAGCACAATTTCCATGTTCCACAAGTCGAATCTCAAT
GTCATGGACAAGCCGGTCTTGAGTCCTGCCTCCACAAGGTCAGCCAGCGTGTCCAGGCGCTACCTGTTTGAGAACAGCGATCAGCCCATT
GACCTGACCAAGTCCAAAAGCAAGAAAGCCGAGTCCTCGCAAGCACAATCTTGTATGTCCCCACCTCAGAAGCACGCTCTGTCTGACATC
GCCGACATGGTCAAAGTCCTCCCCAAAGCCACCACCCCAAAGCCAGCCTCCTCCTCCAGGGTCCCCCCCATGAAGCTGGAAATGGATGTC
AGGCGCTTTGAGGATGTCTCCAGTGAAGTCTCAACTTTGCATAAAAGAAAAGGCCGGCAGTCCAACTGGAATCCTCAGCATCTTCTGATT
CTACAAGCCCAGTTTGCCTCGAGCCTCTTCCAGACATCAGAGGGCAAATACCTGCTGTCTGATCTGGGCCCACAAGAGCGTATGCAAATC
TCTAAGTTTACGGGACTCTCAATGACCACTATCAGTCACTGGCTGGCCAACGTCAAGTACCAGCTTAGGAAAACGGGCGGGACAAAATTT
CTGAAAAACATGGACAAAGGCCACCCCATCTTTTATTGCAGTGACTGTGCCTCCCAGTTCAGAACCCCTTCTACCTACATCAGTCACTTA
GAATCTCACCTGGGTTTCCAAATGAAGGACATGACCCGCTTGTCAGTGGACCAGCAAAGCAAGGTGGAGCAAGAGATCTCCCGGGTATCG
TCGGCTCAGAGGTCTCCAGAAACAATAGCTGCCGAAGAGGACACAGACTCTAAATTCAAGTGTAAGTTGTGCTGTCGGACATTTGTGAGC
AAACATGCGGTAAAACTCCACCTAAGCAAAACGCACAGCAAGTCACCCGAACACCATTCACAGTTTGTAACAGACGTGGATGAAGAATAG
CTCTGCAGGACGAATGCCTTAGTTTCCACTTTCCAGCCTGGATCCCCTCACACTGAACCCTTCTTCGTTGCACCATCCTGCTTCTGACAT
TGAACTCATTGAACTCCTCCTGACACCCTGGCTCTGAGAAGACTGCCAAAAAAAAAAAAAAAAAAAAATCACCCCAGCCATTTCTCTTCA
TCCTCACTAACAATTTGGTAATGAAGTATTGATTTCCACTTCTCTGCTTATGGGCGGTATTAGATTTTCATTGATAAATTGCAATGGGGC

>20353_20353_4_CTNNBL1-TSHZ2_CTNNBL1_chr20_36431450_ENST00000373469_TSHZ2_chr20_51870038_ENST00000603338_length(amino acids)=1173AA_BP=152
MPFDANKLYCSEVLAILLQDNDENRELLGELDGIDVLLQQLSVFKRHNPSTAEEQEMMENLFDSLCSCLMLSSNRERFLKGEGLQLMNLM
LREKKISRSSALKVLDHAMIGPEGTDNCHKFVDILGLRTIFPLFMKSPRKIKKVGTTEKEHEGYAQEEQLKEEEEIKEEEEEEDSGSVAQ
LQGGNDTGTDEELETGPEQKGCFSYQNSPGSHLSNQDAENESLLSDASDQVSDIKSVCGRDASDKKAHTHVRLPNEAHNCMDKMTAVYAN
ILSDSYWSGLGLGFKLSNSERRNCDTRNGSNKSDFDWHQDALSKSLQQNLPSRSVSKPSLFSSVQLYRQSSKMCGTVFTGASRFRCRQCS
AAYDTLVELTVHMNETGHYQDDNRKKDKLRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPT
ISSKMVTPAKKRVFDVNRPCSPDSTTGSFADSFSSQKNANLQLSSNNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMV
TGHFLKVTSSASKKGKQLVLDPLAVEKMQSLSEAPNSDSLAPKPSSNSASDCTASTTELKKESKKERPEETSKDEKVVKSEDYEDPLQKP
LDPTIKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPPLPMGSQVLQIRPNLTNKLRPIAPK
WKVMPLVSMPTHLAPYTQVKKESEDKDEAVKECGKESPHEEASSFSHSEGDSFRKSETPPEAKKTELGPLKEEEKLMKEGSEKEKPQPLE
PTSALSNGCALANHAPALPCINPLSALQSVLNNHLGKATEPLRSPSCSSPSSSTISMFHKSNLNVMDKPVLSPASTRSASVSRRYLFENS
DQPIDLTKSKSKKAESSQAQSCMSPPQKHALSDIADMVKVLPKATTPKPASSSRVPPMKLEMDVRRFEDVSSEVSTLHKRKGRQSNWNPQ
HLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTY
ISHLESHLGFQMKDMTRLSVDQQSKVEQEISRVSSAQRSPETIAAEEDTDSKFKCKLCCRTFVSKHAVKLHLSKTHSKSPEHHSQFVTDV

--------------------------------------------------------------
>20353_20353_5_CTNNBL1-TSHZ2_CTNNBL1_chr20_36431450_ENST00000373473_TSHZ2_chr20_51870038_ENST00000371497_length(transcript)=12158nt_BP=898nt
GGGAAGAGTGCTGTGGTGAGTGAGGGATTTTGCCATGGAGAAGGAGAAGGACCCATAGCAGTTTGTCAGGTTCATGGAATCCGAGCTGGA
CCTAAATGACATCATTCAGGAGATGCACGTGGTGGCCACCATGCCAGACCTGTACCACCTTCTGGTGGAGCTGAATGCTGTACAGTCGCT
TCTCGGCTTGCTCGGACACGATAATACAGATATCCTTTCAGATCTGACCTCAGTAGGAGAGCTGACATGGTGGATGGGCAGGTGGTAGCA
CTGCTGGTACAGAATCTGGAGCGCCTGGATGAGTCTGTGAAAGAGGAGGCAGATGGCGTCCACAACACTCTGGCTATTGTGGAAAACATG
GCTGAGTTCCGGCCTGAGATGTGTACAGAGGGTGCCCAGCAGGGTCTTCTACAGTGGCTGTTGAAGAGGCTGAAGGCAAAGATGCCTTTT
GATGCCAACAAACTGTATTGCAGTGAAGTGCTGGCCATATTGCTCCAGGACAATGATGAAAACAGGGAATTGCTTGGGGAGCTGGATGGA
ATCGATGTGCTTCTTCAGCAGTTATCCGTGTTTAAAAGACACAATCCCAGCACGGCTGAGGAGCAGGAGATGATGGAGAATCTGTTTGAT
TCCCTCTGCTCCTGTCTAATGCTTAGTTCCAATCGTGAGCGCTTCCTGAAGGGCGAGGGTCTTCAGCTGATGAATCTCATGCTCAGGGAA
AAGAAGATCTCCCGGAGCAGTGCCCTGAAAGTGCTGGACCATGCCATGATTGGCCCCGAAGGCACAGACAACTGCCATAAGTTTGTTGAC
ATTCTTGGCTTACGAACCATCTTTCCCCTCTTTATGAAATCTCCCAGGAAGATCAAGAAAGTGGGAACCACTGAGAAGGAACATGAAGGC
TACGCCCAGGAGGAACAGCTGAAAGAAGAGGAGGAAATAAAAGAAGAGGAGGAGGAGGAGGACAGCGGTTCAGTAGCTCAACTGCAGGGT
GGCAATGACACAGGGACGGACGAGGAGCTAGAAACGGGCCCAGAGCAAAAAGGCTGCTTCAGCTACCAGAACTCTCCAGGAAGTCATTTG
TCCAATCAGGATGCCGAGAACGAGTCTCTGCTGAGTGACGCCAGTGATCAGGTGTCGGACATCAAGAGTGTCTGCGGCAGAGATGCCTCA
GACAAGAAAGCACACACTCACGTCAGGCTTCCAAACGAAGCACACAATTGCATGGATAAAATGACCGCTGTCTACGCCAACATCCTGTCG
GATTCCTACTGGTCAGGCCTGGGCCTTGGCTTCAAGCTGTCCAATAGTGAGAGGAGGAACTGTGACACCCGAAACGGCAGCAACAAGAGT
GATTTTGATTGGCACCAAGACGCTCTGTCCAAAAGCCTGCAGCAGAACTTGCCTTCTCGGTCCGTCTCGAAACCCAGCCTGTTCAGCTCG
GTGCAGTTGTACCGACAGAGCAGCAAGATGTGCGGGACTGTGTTCACAGGGGCCAGCAGATTCCGATGCCGACAGTGCAGCGCGGCCTAT
GACACCCTAGTCGAGCTGACTGTGCACATGAATGAAACGGGCCACTATCAAGATGACAACCGCAAAAAGGACAAGCTCAGACCCACGAGC
TATTCAAAGCCCAGGAAAAGGGCTTTCCAGGATATGGACAAAGAGGATGCTCAAAAGGTTCTGAAATGTATGTTTTGTGGCGACTCCTTT
GATTCCCTCCAAGATTTGAGCGTCCACATGATTAAAACAAAACATTACCAAAAAGTGCCTTTGAAGGAGCCAGTCCCAACCATTTCCTCG
AAAATGGTCACCCCGGCTAAGAAACGCGTTTTTGATGTCAATCGGCCGTGTTCCCCCGATTCAACCACAGGATCTTTTGCAGATTCTTTT
TCTTCTCAGAAGAACGCCAACTTGCAGTTGTCCTCCAACAACCGCTATGGCTACCAAAATGGAGCCAGCTACACCTGGCAGTTTGAGGCC
TGCAAGTCCCAGATCTTAAAGTGCATGGAGTGTGGGAGCTCCCATGACACCTTGCAGCAGCTCACCACCCACATGATGGTCACAGGTCAC
TTTCTCAAGGTCACCAGCTCTGCCTCCAAGAAAGGGAAGCAGCTGGTATTAGACCCGTTAGCAGTGGAGAAAATGCAGTCGTTGTCTGAG
GCCCCAAACAGTGATTCTCTGGCTCCCAAGCCATCCAGTAACTCAGCATCAGATTGTACAGCCTCTACAACTGAGTTAAAGAAAGAGAGT
AAAAAAGAAAGGCCAGAGGAAACCAGCAAGGATGAGAAAGTCGTGAAAAGCGAGGACTATGAAGATCCTCTACAAAAACCTTTAGACCCT
ACAATCAAATATCAATACCTAAGGGAGGAAGACTTGGAAGATGGCTCAAAGGGTGGAGGGGACATTTTGAAATCTTTGGAAAATACTGTC
ACCACAGCCATCAACAAAGCCCAAAACGGGGCCCCCAGCTGGAGTGCCTACCCCAGCATCCACGCAGCCTACCAGCTGTCTGAGGGCACC
AAGCCGCCTTTGCCTATGGGATCCCAGGTACTGCAGATCCGGCCTAATCTCACCAACAAGCTGAGGCCCATTGCACCAAAGTGGAAAGTG
ATGCCACTGGTTTCTATGCCCACACACCTGGCCCCTTACACTCAAGTCAAGAAAGAGTCAGAAGACAAAGATGAAGCGGTGAAGGAGTGT
GGGAAAGAAAGTCCCCACGAAGAGGCCTCATCTTTCAGCCACAGTGAGGGCGATTCTTTCCGCAAAAGTGAAACACCTCCAGAAGCCAAA
AAGACCGAGCTGGGTCCCCTGAAGGAGGAGGAGAAGCTGATGAAAGAGGGCAGCGAGAAGGAGAAACCCCAGCCCCTGGAGCCCACATCT
GCTCTGAGCAATGGGTGCGCCCTCGCCAACCACGCCCCGGCCCTGCCATGCATCAACCCACTCAGCGCCCTGCAGTCCGTCCTGAACAAT
CACTTGGGCAAAGCCACGGAGCCCTTGCGCTCACCTTCCTGCTCCAGCCCAAGTTCAAGCACAATTTCCATGTTCCACAAGTCGAATCTC
AATGTCATGGACAAGCCGGTCTTGAGTCCTGCCTCCACAAGGTCAGCCAGCGTGTCCAGGCGCTACCTGTTTGAGAACAGCGATCAGCCC
ATTGACCTGACCAAGTCCAAAAGCAAGAAAGCCGAGTCCTCGCAAGCACAATCTTGTATGTCCCCACCTCAGAAGCACGCTCTGTCTGAC
ATCGCCGACATGGTCAAAGTCCTCCCCAAAGCCACCACCCCAAAGCCAGCCTCCTCCTCCAGGGTCCCCCCCATGAAGCTGGAAATGGAT
GTCAGGCGCTTTGAGGATGTCTCCAGTGAAGTCTCAACTTTGCATAAAAGAAAAGGCCGGCAGTCCAACTGGAATCCTCAGCATCTTCTG
ATTCTACAAGCCCAGTTTGCCTCGAGCCTCTTCCAGACATCAGAGGGCAAATACCTGCTGTCTGATCTGGGCCCACAAGAGCGTATGCAA
ATCTCTAAGTTTACGGGACTCTCAATGACCACTATCAGTCACTGGCTGGCCAACGTCAAGTACCAGCTTAGGAAAACGGGCGGGACAAAA
TTTCTGAAAAACATGGACAAAGGCCACCCCATCTTTTATTGCAGTGACTGTGCCTCCCAGTTCAGAACCCCTTCTACCTACATCAGTCAC
TTAGAATCTCACCTGGGTTTCCAAATGAAGGACATGACCCGCTTGTCAGTGGACCAGCAAAGCAAGGTGGAGCAAGAGATCTCCCGGGTA
TCGTCGGCTCAGAGGTCTCCAGAAACAATAGCTGCCGAAGAGGACACAGACTCTAAATTCAAGTGTAAGTTGTGCTGTCGGACATTTGTG
AGCAAACATGCGGTAAAACTCCACCTAAGCAAAACGCACAGCAAGTCACCCGAACACCATTCACAGTTTGTAACAGACGTGGATGAAGAA
TAGCTCTGCAGGACGAATGCCTTAGTTTCCACTTTCCAGCCTGGATCCCCTCACACTGAACCCTTCTTCGTTGCACCATCCTGCTTCTGA
CATTGAACTCATTGAACTCCTCCTGACACCCTGGCTCTGAGAAGACTGCCAAAAAAAAAAAAAAAAAAAAATCACCCCAGCCATTTCTCT
TCATCCTCACTAACAATTTGGTAATGAAGTATTGATTTCCACTTCTCTGCTTATGGGCGGTATTAGATTTTCATTGATAAATTGCAATGG
GGCTGTCTCGTCTCCACAGTACCCTTTTCACTGTCACAAGAAAACAAAGTGCCACCGAAGAAAAGTAATGACTGAGAGCATTGATGTACT
TATTTTGTCAGTTTGTAACAGGAAAGTGGGGGGGAGTCTAAGTCTTCATAGTCTAATGTCCAAGTGGGTTGCACTAGATGTAGACACTTG
GAGGCTTACTTTTCATGGTAATGTCCATTTCCTATTTATAACCCCTCTGGGAACGTTTGTCTAAAGGAAATGTTTCTGTTCAGTGTAACA
ATTACAGTTGCACCTGGATTGCCCAGTCCTGCCCCTGCACTAGGGGACCATTAATCACTGCAAAGTAGAAGAATTATTAAGTTAAACCAG
AGTTTGAGCCAAGAAAACCCCTGAACAATGTTCATCTTCTGTGAAACTTGCTCAAATAGTTAAGCTTAACCATGTTGCTGCCAAAGACTT
TTCCTATGCAGTGGTGGGGCACCTTGATCATCATCATTATCTTGATTGGCTGAAAAAAAAATAGTTTTAAGCACACACCACTGTCTATGA
GAACTGCAAATTGGGAGAATAGGTGAAATGCAGAATCTGAGAGAACGCGAGAAGATGAGATCATTACAGGGTGGAAAGTTCTGCAGCAGC
CTTTTCTGGTAATCCCTTTCTGCAGAACCTGATGTTTATGGGCTCTAAAACGCAGCTTAGCTTTAGAAGCAACAGAAAGCATGAAATAGG
GTGTCCATTTTAAATGTGTTCCTGCAACTTTTTTCATTAAAACTTTGAGGGCCCAATTTTAATTTGTGGAATATTCCCGTTAATAATGAG
ATCTAATTAAGACATCCATTAAAAGCCCGTTAAAGTTAATTTAACGTAAAAATTCCAATAGAACTGTATTAGATTTTCTCCATTAAATTA
ACGTTATGGATTTTTAACGGATGTCTTAATTATACGTTATTATTAACGGGAATACTGTATTACACAGATTAAAATCAGGTCCTAAGTCAA
CTTGGAAGAGCTAAGAGCATGTTTTAATATTAAAAGTCTTGCATACCTAGTGCACAGTTTGGAGACGCAAGGATAGATCTGTTTACTCTA
GTTGAACATTTTCTATACAATTGAAAGCAACCTATAATAGATAAATCCATCATTGCATTTAAACAATGAATTTCCTTATTCTCAAAGGAC
AAATACGTCTGGATTATGTGGTAAATTGCTACTCAGCTATGGTGAAATATTTATACTATTCTAGGCACAACACTAGGAACTAGGTGATTC
TGAAACAAAAGGAATATTTTCTGTTGTTGCTTTAATTACCAAGGTTATTTTTTTTTAATCTCAACACTGACAAAATGAAACCAAATATCT
CTTCCTCACCATTTCTCAAGGAGGCTGCCTGTTGGAATTGTTTTGGAAATTTTGACATGATCCCTAAATTCAACATTGGGATTAAAAAAA
AAAAAAAACTTCTTATTTACCTCCTAGGGAAAGTGTTGCCCTTATGCCACATATAATAGCAAATTGCTTTTTTTATGGCATGCATAACCT
AGATGGGAAAAAATATGGCGCTTCGGGGAAGGAGGGAAAAAGTAAATGAAGTTCCAGGAATGTCATTCTGAAGTAATGAGGCATGGACAG
AAAATATACCCCTCACATCATCGGATTGAGATGGCAGTCGAAATAGCTTCATTGAAGTGTCAGCACTCATCCATCAATCAATCACCCACA
AGGAAAAATAGCAACAGTACAACGGGGTGGCTTTTATGGGATTTACTCATGGGCATAGGGAATAGCGGCTCAAATGTAGTTCTGACATGA
AAAGCAAGGTGCTGATATTATTTTTTATGATGGGAGGATCATAAAGTGAATTGAGAACAGTGAGGTCTGTCTTTGCTTAACCTATTCAAC
CAGAAATGAATGGAGCTCGACTGGAAAGGAACAGTCTTCAGATGGGTTAAGATTGAAGGGTGGACTGGACTCTACTGAGCACCGTCCTTC
AACAAGGAAATTCTATTAAAGGAAAATCAATGCATTAGTATTGGGGTTCTCGTAGCTGTTAAAAATTGTCTGCTCCAATCCAGGGTTATT
AGGCCAAAGTTACATAATTCAGATCTCACTGCAACCATCCAAAAGTGGATTCTCGAGCCCTTGCTCCAATGGGGGGAGGAGATCAATACA
ATTCCCAATTCCATGGAAATTGTTTCCCTTCTAAGGAAGAAAAAATAAATCATCTGCTTCAACATATAATCGATATGGTTTTGTTAGCGT
AATTTCTATGGTGGGTGGGGTGGGAGGTGAGAGAAAAAAATATTGATAAATTTGGTAAGACAGGTGAATTGCCGCCTGGCAACCGTGCAT
GTCACTGCCGAGGGATGGCTGCTAAGGTTCACCTTAGAAAACAAGATCTGGGCTGGCACTGGGGCATACATCACCACTCAGCATATTCCT
AGAGGCCAGGCCTGTCTTCACTCAGCCAGCCCTCTGAGGCTTCTAGAAACTTCTTTCTGGAGGAAAAAAACTAAATAACATAAACTCAGG
AGAATGTCTTTACCCACCTTCATACCACTGCTTTCTTTTTGCTGAATAAAACACAGTTCTGATAAGTAAGAACTTTAGAATTGGAAAGGA
GGCTGACATGCAAATATAATGCAAATTACCCTCAAGTATCGCCATTCTTCCACCACCTCTTGGTACCAGTGAGAGCGAGAGATTGCCTTT
TCTTCCCCATCCCTCCTTCCAGCTAAGACCACCAACCAGCTGCAAATTGAGATGTCCATTTAAAAATTTATATGTCAATATTTAAATGTT
ACATATTTGGCCCTATTTTGTAGTTCAGCAAATCCTCCAAATACACAGCATGTTACAAGGCACTGGTGGCACAGGGCACAACAGGAAATG
ATATTTATTTAGCAAATTCATTTAACAAATATTATTGGGCACCTGTTATGTGAGACACTGTCCTAGGCACTGTGGGATAACAACAGCAAA
CACTTCACACAACAGCCTGGCCTTCCTGTGTTTTACAACAGCTCCTAAAGATAGCTGATATCAAGACATTTGAGGGACACAGTTCATGTA
GAATCAAAATATTAGTATTTCAGAATAAGGATTTTTTTTCTGAAAAGCATACAGAGAGGAAACAGCTTAAAAATAGGTCAAGACCTAAAA
ACAGAATATAATCACGGAATAAACTGGATAACCCAGACAGTCCCCACAGAATTTCTTTCAGGTCACAGATTTCTTAAAACTCACCCCCAA
AATGTGCCTGCTTGGTTGTTTGAATCTTGCATAATTAATGTCACAGGCGCAAGCCGCTGAACTTAGTTGAGATGCAGAAAACAAACAAAT
GCAATGACATATCTGAGAAGCATTTATGTAACTCCGGTTAAGTGGTGAGGAGGGGTGTGTGAAGACAGTGTGCATGCATGAGTGTGTATT
CATATATATGTGTATACATATGAATTTCACTGTTATTTTCCAGGGTCTATGGACAATGTGGCAGTAAGAGTCTATGATGTTCTGAAACTT
TTCACAGTAAATCCAAAGATTACAGACCTTACAAGGTGCTTGCATTCTGTTGCTTTTCCATCTGTCACTTCTCAGGTTATTTGACTGTGT
TCAAACCTTCTTTTCTTTTTCATTGAGTTTCATTTTTTAAGCTTGTTAAATGCTTTTGTTTAAAAAAAAAAAAAAAACCCCAAATGTCAT
TTTTCACATTATCCTCTCTTCTCTGCAACAAGGATAGTAAGATGTAGATGAATGCAAAAATAATAACAACAATAAGGAAATATATTAAAG
CTTTAAAATATGCACATATGTAGTTCTAAAGAGCAATAACGGTAGTATCTATTTCGAACATGCATTAGGCAAAAAAGAAATCAAAACTGA
AATTTTCGTGTATTTTTCCCCTTGTAAGATGTTCAAATGCTAACTTCATTTTCTCCTTTCCTCTATGTGGCACTTTCTCAAAATATCTAT
GAAATACTTTTAGACAAAGATTGAGCTGGAGAAAGAGATACAAATTTCCATCCCCCCAGACAGAGAGACATATTTCCATTGTAGGAAGGC
ATTAAACATTTTGAAACTTGTGAATCATCTTTAGAATTTCTACTGGGGAATTTTACTTCTTCATCCAAAGTAAAAGCCACTTATCTCCTT
TGGTTCCCAGTGACAGATTCAGAGGCATACGCAGATATACAATTTTCAGGCTCTAGTTAATCTTCTTCCAATAGTTACGAACAATGGGCT
AACAGGCGTGGGTGTTTCTCCAAAAATTATTCATGCACAAGGCAGCCCAAAGCTTCAGGGAAAACTAGAAATGTGTTATGGATTAGAATA
GGACTGTTTTAAAATGCTAGTACCAGGTGGAACGCTATTTCTGCAACAGGACTCTGTCCATTTCCTTTGGAACAATATATTCCAAGTAAA
ATGGCTCTTCCAAGGAATGACACCTTTACTTGACACCCTTCGGCATACAAATGATTTTACCAATAGCCATGATTATTATTAAGGCCTTTT
AAAATACAGGCTGTTTGAAAAAAGACAGATTAAATATTCACAGCCTTTGTATCATGGTTATTTGCTTAAAACAGCTTTTAGAAGTACAAG
TAATAACTTTTTGATAAGAAACCCCAGGAGAAACTTTTTGGTAAGAAACCTCAAAAAATTTGAACAAAGGCATTACAAAAAAAAAAAAAA
AACTAACCACTCCATTCAACTCTCTCAGAAAATAAATTTCAATGTGTTCAATGAATTGTCTTGAACCTGAAACCTGCATTTAGATATCAG
TCCCCTGCCAATAGCTAATATTAACAGAATTTGAACAATCATACAATTATGTCTCAAATGTGAAGACTTTGTACAGTAATATTTTCACTT
TCTAAATGACCCATATAACATTCAGGAATTATAGATGTGTATGTATATTTTTTAAGTACAGAAAGTTCAGCCAGTCTTCAGAGAAGTAAA
AGTGATGTCTATTGTGCATTGAAGTAAATATTACAAACATTCCAGTTTCGCAATACAATACTTGAGCTTTCGAACACCTCAGACACTAGA
ATGTGTAATGCGAGTCAAAAAAGCTGACATACAAAACAATTCCCATTTGGCTCAGGGTTCCTAAATGTCACAATATCTTGGGTAAAATAT
ACTTTTTGATTTCCTGATGATGTCCTTCTAATCCCTTCTGACTTTGATTCCTAACAGCCAGGCACTGTTGACATGAATCATTAACTTCCA
AACCCCTTTAAAATCAAGAAGCTAGGTGATCATACAGTCATTTCAATGGCCAACCAGTTCTTGCTCTACAGAGCTTTTACACCTTTTTGG
GAAACCTGATATCAAACACATTTATGTTATATATTTGCTCCCTTGCATTAATTCTAGATTTTTTTTTAATTTCTTTTAGAAAGGGCAGGG
GGGAAGTGGGTCAGAGCAAGGTTCAAGAATCACATTCATCCTTGCTCTAAAGTGTTTACTTGCCAGCAAAGAAAGGCAAACACATTTTTA
TATTCAGAAAGCAGACCGGTCATTTTCAAAGAAAAATGACTGCAACCATGCCTGTAGAATGTTTCTGTGCAAGCGCACTAATTTTCTATC
ACCTGCATGCTGTATATAATACATTTGCCTGTATACTAGGAAGAAAAACCAGGCTGTTTTCCCTGAGTACAATGCAGCTTGGATGGCTGG
GAGCGTAAGCCTTCCGTGCATTTTTATAGTGTACATATTTGTATATACTAACTATATCGCCATGTATGAACACAGATTTTGTTATATTTG
CTTGTTTCTGTTTCCTACCAAACTGGCCCACAATGGGGATTCTTTTGTATAGAAAAAATATGCTTGTAATTTTTTCCTGGTCATTCTCTT
TCAATAGCTTATGAAAGAATTAGATCTGAGTTTACAAAGAAACTATAAGAACCAAGTTTGTCTGTCTGCATGAGTCCCGTCCAATTGCTG
GATCTAGGGAGGAACCAACTTCCTAATTCAGAGTTTTCCTTTTAAAGGCATGCTTTACCCCCATGGGAAAACTGCACACTCATCCATGTA
GAATTATTCTCTTTGTATTTTATCTAATAGTGCCTGAAAATTTTTTTAATGTCTTCTTAGAAGAAGAATTCATAATTGTCAAAATTTGAA
ACATTAGCTTAATTTTGTTTTTATGACCTCAAGATTCTTCTCCTTATTTATTCGGTTGCTGTTGTAATGGGGCCCCAGGCCATTCCTGAC
ATCGGCGTGTTCTTCTTCTGCATTAAGGATGTTTTTGAAATTACAGAGATTATTGAGCCAACAGGCTGTTTTAATCAAAACCATGTTTCA
CTTCTTTTTGATGATTATAAATTGTCCTTGCAATGAAAAAAAAAAAAGAACTTTTCTGCTAGGAAGATTATACCACCCTGTGGCCAAACA
GATTCATCACAGATAGGCATCTATGCCCATTTCTCTGGGATCTGGAAAATTCTTCCCTTGGCTGACCCCAATTTCTTTTACTCCCCATTA
TCCTGAATATTAGCTTTCAATGCAGTCACTATTTGACATTTCCAAAGGCTTTGCCGCATTGTCACTGCCCAAAGACAAACAACCACTGGA
AATGATGGCTTTCCTGCTTGAAACGAAGGGGGCCAGGTGCAGTGGCTCAAGCCTGTAACCCCTGCACTTTGGAAGGCTGAGGCAGGCGGA
TCACTTGAGGTCAGGAGTTTCAGACCAACCTGGCCAACATGGCAAAACCTCGTCTCTACTAAAAATACAAAAAACATTAGCAGGGCATGG
TGGTGCGTGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAAGAGAATTGCTTGAGCCCGGGAGGCGAAGGTTGCAGTGAGCTGAGATG
GTGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTGTGTCTCAAAAAAAAAAAAAAGAATGGATTTTCAGAAAAAGTGCTCCCTTTC
CTGTCCTGTGGTGCCACCATCCTGTCCTCCTTCGTAATCATGAACAATCTGATCTTGAACTCCCACATAACTTAAATCAGGCAAAAAGAA
ACATTCACAGCGTCCCCTTGCTGAATAAAAATGACTTTGTTTGGAGGCACTTAAGATGTATGCCTGTGTGTGGTGCCGCAGCATTGAAAT
TATCTGTAGAAGGGGAATTTTTTTTAAAAATACAATTTTATCACTAGAAATAAATTCCGATGGTGGAAACGAAGAAAACCCTTAAATTAT
ATCACAAAAGCCATTATTTTTTGCATCCAAAGAGTTTTTTTTTTTAAGGAAAATCATTCTACTTTGAGAACTGTAATTAAAGCCCTAAAT
AACAGACACTACTTTGTTGAGCTATTGTGAAAAAAAAACAACACATTCGCCAAGGTTATATGGAGCCCCTGATTTCCATCAAAAAGGTTT
CTATAAGTATATTATTTACATTTTTATACATGATAACTCTTGCCTTTGTGTTGAAAAAAAAAAAGTCTCTTTTTTTTCCCCCACTCAGCA
GTTATTGGAAATAGACTGTTCCCATCTGAAACCGTATCGTAATTTGCATCAGGAAACCCAACTGCTGACATTGAGGACCTGGGTGTGTTC
AATTATGATTTTGCTGGAGGCTGTCCCTCATTTTAATGCTGCAGCTATTGAACCACCTTCCTGAAACCTAGCTGATACGGAATAGCAGAG
ACATGCCTCTCAACACCATTAGCTTTGCAAATGGCTTCATTTCAGTCAACGTCGACTTCTGCTTTGGCCAATTGAAAAATGAAAATTAAA
GGAGAGAAGAAAAAAAACACAGATGCACTTAAAACATGAAAAGAATTATTTATATGATAAAAATATATTTAGCTTTTCAAAGCACAAGAC
TGAATAGAAGTGCTCTTTTTATGCTTTCTGGAGATGTTACTGTTAAATGTCTTTCTACATCAGGCTTAATAAATCTGTAATGACATTTGA

>20353_20353_5_CTNNBL1-TSHZ2_CTNNBL1_chr20_36431450_ENST00000373473_TSHZ2_chr20_51870038_ENST00000371497_length(amino acids)=1238AA_BP=217
MVDGQVVALLVQNLERLDESVKEEADGVHNTLAIVENMAEFRPEMCTEGAQQGLLQWLLKRLKAKMPFDANKLYCSEVLAILLQDNDENR
ELLGELDGIDVLLQQLSVFKRHNPSTAEEQEMMENLFDSLCSCLMLSSNRERFLKGEGLQLMNLMLREKKISRSSALKVLDHAMIGPEGT
DNCHKFVDILGLRTIFPLFMKSPRKIKKVGTTEKEHEGYAQEEQLKEEEEIKEEEEEEDSGSVAQLQGGNDTGTDEELETGPEQKGCFSY
QNSPGSHLSNQDAENESLLSDASDQVSDIKSVCGRDASDKKAHTHVRLPNEAHNCMDKMTAVYANILSDSYWSGLGLGFKLSNSERRNCD
TRNGSNKSDFDWHQDALSKSLQQNLPSRSVSKPSLFSSVQLYRQSSKMCGTVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNRK
KDKLRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNRPCSPDST
TGSFADSFSSQKNANLQLSSNNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLAV
EKMQSLSEAPNSDSLAPKPSSNSASDCTASTTELKKESKKERPEETSKDEKVVKSEDYEDPLQKPLDPTIKYQYLREEDLEDGSKGGGDI
LKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPPLPMGSQVLQIRPNLTNKLRPIAPKWKVMPLVSMPTHLAPYTQVKKESED
KDEAVKECGKESPHEEASSFSHSEGDSFRKSETPPEAKKTELGPLKEEEKLMKEGSEKEKPQPLEPTSALSNGCALANHAPALPCINPLS
ALQSVLNNHLGKATEPLRSPSCSSPSSSTISMFHKSNLNVMDKPVLSPASTRSASVSRRYLFENSDQPIDLTKSKSKKAESSQAQSCMSP
PQKHALSDIADMVKVLPKATTPKPASSSRVPPMKLEMDVRRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSD
LGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQMKDMTRLSVDQQSK

--------------------------------------------------------------
>20353_20353_6_CTNNBL1-TSHZ2_CTNNBL1_chr20_36431450_ENST00000373473_TSHZ2_chr20_51870038_ENST00000603338_length(transcript)=4307nt_BP=898nt
GGGAAGAGTGCTGTGGTGAGTGAGGGATTTTGCCATGGAGAAGGAGAAGGACCCATAGCAGTTTGTCAGGTTCATGGAATCCGAGCTGGA
CCTAAATGACATCATTCAGGAGATGCACGTGGTGGCCACCATGCCAGACCTGTACCACCTTCTGGTGGAGCTGAATGCTGTACAGTCGCT
TCTCGGCTTGCTCGGACACGATAATACAGATATCCTTTCAGATCTGACCTCAGTAGGAGAGCTGACATGGTGGATGGGCAGGTGGTAGCA
CTGCTGGTACAGAATCTGGAGCGCCTGGATGAGTCTGTGAAAGAGGAGGCAGATGGCGTCCACAACACTCTGGCTATTGTGGAAAACATG
GCTGAGTTCCGGCCTGAGATGTGTACAGAGGGTGCCCAGCAGGGTCTTCTACAGTGGCTGTTGAAGAGGCTGAAGGCAAAGATGCCTTTT
GATGCCAACAAACTGTATTGCAGTGAAGTGCTGGCCATATTGCTCCAGGACAATGATGAAAACAGGGAATTGCTTGGGGAGCTGGATGGA
ATCGATGTGCTTCTTCAGCAGTTATCCGTGTTTAAAAGACACAATCCCAGCACGGCTGAGGAGCAGGAGATGATGGAGAATCTGTTTGAT
TCCCTCTGCTCCTGTCTAATGCTTAGTTCCAATCGTGAGCGCTTCCTGAAGGGCGAGGGTCTTCAGCTGATGAATCTCATGCTCAGGGAA
AAGAAGATCTCCCGGAGCAGTGCCCTGAAAGTGCTGGACCATGCCATGATTGGCCCCGAAGGCACAGACAACTGCCATAAGTTTGTTGAC
ATTCTTGGCTTACGAACCATCTTTCCCCTCTTTATGAAATCTCCCAGGAAGATCAAGAAAGTGGGAACCACTGAGAAGGAACATGAAGGC
TACGCCCAGGAGGAACAGCTGAAAGAAGAGGAGGAAATAAAAGAAGAGGAGGAGGAGGAGGACAGCGGTTCAGTAGCTCAACTGCAGGGT
GGCAATGACACAGGGACGGACGAGGAGCTAGAAACGGGCCCAGAGCAAAAAGGCTGCTTCAGCTACCAGAACTCTCCAGGAAGTCATTTG
TCCAATCAGGATGCCGAGAACGAGTCTCTGCTGAGTGACGCCAGTGATCAGGTGTCGGACATCAAGAGTGTCTGCGGCAGAGATGCCTCA
GACAAGAAAGCACACACTCACGTCAGGCTTCCAAACGAAGCACACAATTGCATGGATAAAATGACCGCTGTCTACGCCAACATCCTGTCG
GATTCCTACTGGTCAGGCCTGGGCCTTGGCTTCAAGCTGTCCAATAGTGAGAGGAGGAACTGTGACACCCGAAACGGCAGCAACAAGAGT
GATTTTGATTGGCACCAAGACGCTCTGTCCAAAAGCCTGCAGCAGAACTTGCCTTCTCGGTCCGTCTCGAAACCCAGCCTGTTCAGCTCG
GTGCAGTTGTACCGACAGAGCAGCAAGATGTGCGGGACTGTGTTCACAGGGGCCAGCAGATTCCGATGCCGACAGTGCAGCGCGGCCTAT
GACACCCTAGTCGAGCTGACTGTGCACATGAATGAAACGGGCCACTATCAAGATGACAACCGCAAAAAGGACAAGCTCAGACCCACGAGC
TATTCAAAGCCCAGGAAAAGGGCTTTCCAGGATATGGACAAAGAGGATGCTCAAAAGGTTCTGAAATGTATGTTTTGTGGCGACTCCTTT
GATTCCCTCCAAGATTTGAGCGTCCACATGATTAAAACAAAACATTACCAAAAAGTGCCTTTGAAGGAGCCAGTCCCAACCATTTCCTCG
AAAATGGTCACCCCGGCTAAGAAACGCGTTTTTGATGTCAATCGGCCGTGTTCCCCCGATTCAACCACAGGATCTTTTGCAGATTCTTTT
TCTTCTCAGAAGAACGCCAACTTGCAGTTGTCCTCCAACAACCGCTATGGCTACCAAAATGGAGCCAGCTACACCTGGCAGTTTGAGGCC
TGCAAGTCCCAGATCTTAAAGTGCATGGAGTGTGGGAGCTCCCATGACACCTTGCAGCAGCTCACCACCCACATGATGGTCACAGGTCAC
TTTCTCAAGGTCACCAGCTCTGCCTCCAAGAAAGGGAAGCAGCTGGTATTAGACCCGTTAGCAGTGGAGAAAATGCAGTCGTTGTCTGAG
GCCCCAAACAGTGATTCTCTGGCTCCCAAGCCATCCAGTAACTCAGCATCAGATTGTACAGCCTCTACAACTGAGTTAAAGAAAGAGAGT
AAAAAAGAAAGGCCAGAGGAAACCAGCAAGGATGAGAAAGTCGTGAAAAGCGAGGACTATGAAGATCCTCTACAAAAACCTTTAGACCCT
ACAATCAAATATCAATACCTAAGGGAGGAAGACTTGGAAGATGGCTCAAAGGGTGGAGGGGACATTTTGAAATCTTTGGAAAATACTGTC
ACCACAGCCATCAACAAAGCCCAAAACGGGGCCCCCAGCTGGAGTGCCTACCCCAGCATCCACGCAGCCTACCAGCTGTCTGAGGGCACC
AAGCCGCCTTTGCCTATGGGATCCCAGGTACTGCAGATCCGGCCTAATCTCACCAACAAGCTGAGGCCCATTGCACCAAAGTGGAAAGTG
ATGCCACTGGTTTCTATGCCCACACACCTGGCCCCTTACACTCAAGTCAAGAAAGAGTCAGAAGACAAAGATGAAGCGGTGAAGGAGTGT
GGGAAAGAAAGTCCCCACGAAGAGGCCTCATCTTTCAGCCACAGTGAGGGCGATTCTTTCCGCAAAAGTGAAACACCTCCAGAAGCCAAA
AAGACCGAGCTGGGTCCCCTGAAGGAGGAGGAGAAGCTGATGAAAGAGGGCAGCGAGAAGGAGAAACCCCAGCCCCTGGAGCCCACATCT
GCTCTGAGCAATGGGTGCGCCCTCGCCAACCACGCCCCGGCCCTGCCATGCATCAACCCACTCAGCGCCCTGCAGTCCGTCCTGAACAAT
CACTTGGGCAAAGCCACGGAGCCCTTGCGCTCACCTTCCTGCTCCAGCCCAAGTTCAAGCACAATTTCCATGTTCCACAAGTCGAATCTC
AATGTCATGGACAAGCCGGTCTTGAGTCCTGCCTCCACAAGGTCAGCCAGCGTGTCCAGGCGCTACCTGTTTGAGAACAGCGATCAGCCC
ATTGACCTGACCAAGTCCAAAAGCAAGAAAGCCGAGTCCTCGCAAGCACAATCTTGTATGTCCCCACCTCAGAAGCACGCTCTGTCTGAC
ATCGCCGACATGGTCAAAGTCCTCCCCAAAGCCACCACCCCAAAGCCAGCCTCCTCCTCCAGGGTCCCCCCCATGAAGCTGGAAATGGAT
GTCAGGCGCTTTGAGGATGTCTCCAGTGAAGTCTCAACTTTGCATAAAAGAAAAGGCCGGCAGTCCAACTGGAATCCTCAGCATCTTCTG
ATTCTACAAGCCCAGTTTGCCTCGAGCCTCTTCCAGACATCAGAGGGCAAATACCTGCTGTCTGATCTGGGCCCACAAGAGCGTATGCAA
ATCTCTAAGTTTACGGGACTCTCAATGACCACTATCAGTCACTGGCTGGCCAACGTCAAGTACCAGCTTAGGAAAACGGGCGGGACAAAA
TTTCTGAAAAACATGGACAAAGGCCACCCCATCTTTTATTGCAGTGACTGTGCCTCCCAGTTCAGAACCCCTTCTACCTACATCAGTCAC
TTAGAATCTCACCTGGGTTTCCAAATGAAGGACATGACCCGCTTGTCAGTGGACCAGCAAAGCAAGGTGGAGCAAGAGATCTCCCGGGTA
TCGTCGGCTCAGAGGTCTCCAGAAACAATAGCTGCCGAAGAGGACACAGACTCTAAATTCAAGTGTAAGTTGTGCTGTCGGACATTTGTG
AGCAAACATGCGGTAAAACTCCACCTAAGCAAAACGCACAGCAAGTCACCCGAACACCATTCACAGTTTGTAACAGACGTGGATGAAGAA
TAGCTCTGCAGGACGAATGCCTTAGTTTCCACTTTCCAGCCTGGATCCCCTCACACTGAACCCTTCTTCGTTGCACCATCCTGCTTCTGA
CATTGAACTCATTGAACTCCTCCTGACACCCTGGCTCTGAGAAGACTGCCAAAAAAAAAAAAAAAAAAAAATCACCCCAGCCATTTCTCT
TCATCCTCACTAACAATTTGGTAATGAAGTATTGATTTCCACTTCTCTGCTTATGGGCGGTATTAGATTTTCATTGATAAATTGCAATGG

>20353_20353_6_CTNNBL1-TSHZ2_CTNNBL1_chr20_36431450_ENST00000373473_TSHZ2_chr20_51870038_ENST00000603338_length(amino acids)=1238AA_BP=217
MVDGQVVALLVQNLERLDESVKEEADGVHNTLAIVENMAEFRPEMCTEGAQQGLLQWLLKRLKAKMPFDANKLYCSEVLAILLQDNDENR
ELLGELDGIDVLLQQLSVFKRHNPSTAEEQEMMENLFDSLCSCLMLSSNRERFLKGEGLQLMNLMLREKKISRSSALKVLDHAMIGPEGT
DNCHKFVDILGLRTIFPLFMKSPRKIKKVGTTEKEHEGYAQEEQLKEEEEIKEEEEEEDSGSVAQLQGGNDTGTDEELETGPEQKGCFSY
QNSPGSHLSNQDAENESLLSDASDQVSDIKSVCGRDASDKKAHTHVRLPNEAHNCMDKMTAVYANILSDSYWSGLGLGFKLSNSERRNCD
TRNGSNKSDFDWHQDALSKSLQQNLPSRSVSKPSLFSSVQLYRQSSKMCGTVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNRK
KDKLRPTSYSKPRKRAFQDMDKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNRPCSPDST
TGSFADSFSSQKNANLQLSSNNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLAV
EKMQSLSEAPNSDSLAPKPSSNSASDCTASTTELKKESKKERPEETSKDEKVVKSEDYEDPLQKPLDPTIKYQYLREEDLEDGSKGGGDI
LKSLENTVTTAINKAQNGAPSWSAYPSIHAAYQLSEGTKPPLPMGSQVLQIRPNLTNKLRPIAPKWKVMPLVSMPTHLAPYTQVKKESED
KDEAVKECGKESPHEEASSFSHSEGDSFRKSETPPEAKKTELGPLKEEEKLMKEGSEKEKPQPLEPTSALSNGCALANHAPALPCINPLS
ALQSVLNNHLGKATEPLRSPSCSSPSSSTISMFHKSNLNVMDKPVLSPASTRSASVSRRYLFENSDQPIDLTKSKSKKAESSQAQSCMSP
PQKHALSDIADMVKVLPKATTPKPASSSRVPPMKLEMDVRRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSD
LGPQERMQISKFTGLSMTTISHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQMKDMTRLSVDQQSK

--------------------------------------------------------------
>20353_20353_7_CTNNBL1-TSHZ2_CTNNBL1_chr20_36431450_ENST00000405275_TSHZ2_chr20_51870038_ENST00000371497_length(transcript)=12635nt_BP=1375nt
TGACGGGCCCGCGGTCTGGGCGTGAGTGCAGGGAAGTGGAGTATTTGCTGGGCCGGGTACCATGGACGTGGGCGAACTTCTGAGCTACCA
GGGGCATGGATGGAGACACGCACACACACAGGCAATAGGCCTCAAGATTATTGGCGAGTAAAGGCATCTATCTATTATCGTGAAGCCTAC
TCTGAGCTTTGACCCAATAGGGGCACAAAACGTCCCCGGGATGATGAAGAGGAGGAGCAGAAGATGCGTCGGAAACAAACTGGTACTCGA
GAACGCGGCCGCTATCGGGAAGAAGAAATGACTGTGGTGGAGGAAGCGGATGATGACAAAAAAAGGCTGCTGCAGATTATTGACAGAGAT
GGGGAAGAGGAAGAGGAAGAGGAGGAGCCATTGGATGAAAGCTCAGTGAAGAAAATGATCCTCACATTTGAAAAGAGATCATATAAAAAC
CAAGAATTGCGGATTAAGTTTCCAGACAATCCAGAGAAGTTCATGGAATCCGAGCTGGACCTAAATGACATCATTCAGGAGATGCACGTG
GTGGCCACCATGCCAGACCTGTACCACCTTCTGGTGGAGCTGAATGCTGTACAGTCGCTTCTCGGCTTGCTCGGACACGATAATACAGAT
GTGTCCATAGCTGTGGTCGATTTGCTTCAGGAATTAACAGATATAGACACCCTCCATGAGAGTGAAGAGGGAGCAGAAGTGCTCATCGAT
GCTCTGGTGGATGGGCAGGTGGTAGCACTGCTGGTACAGAATCTGGAGCGCCTGGATGAGTCTGTGAAAGAGGAGGCAGATGGCGTCCAC
AACACTCTGGCTATTGTGGAAAACATGGCTGAGTTCCGGCCTGAGATGTGTACAGAGGGTGCCCAGCAGGGTCTTCTACAGTGGCTGTTG
AAGAGGCTGAAGGCAAAGATGCCTTTTGATGCCAACAAACTGTATTGCAGTGAAGTGCTGGCCATATTGCTCCAGGACAATGATGAAAAC
AGGGAATTGCTTGGGGAGCTGGATGGAATCGATGTGCTTCTTCAGCAGTTATCCGTGTTTAAAAGACACAATCCCAGCACGGCTGAGGAG
CAGGAGATGATGGAGAATCTGTTTGATTCCCTCTGCTCCTGTCTAATGCTTAGTTCCAATCGTGAGCGCTTCCTGAAGGGCGAGGGTCTT
CAGCTGATGAATCTCATGCTCAGGGAAAAGAAGATCTCCCGGAGCAGTGCCCTGAAAGTGCTGGACCATGCCATGATTGGCCCCGAAGGC
ACAGACAACTGCCATAAGTTTGTTGACATTCTTGGCTTACGAACCATCTTTCCCCTCTTTATGAAATCTCCCAGGAAGATCAAGAAAGTG
GGAACCACTGAGAAGGAACATGAAGGCTACGCCCAGGAGGAACAGCTGAAAGAAGAGGAGGAAATAAAAGAAGAGGAGGAGGAGGAGGAC
AGCGGTTCAGTAGCTCAACTGCAGGGTGGCAATGACACAGGGACGGACGAGGAGCTAGAAACGGGCCCAGAGCAAAAAGGCTGCTTCAGC
TACCAGAACTCTCCAGGAAGTCATTTGTCCAATCAGGATGCCGAGAACGAGTCTCTGCTGAGTGACGCCAGTGATCAGGTGTCGGACATC
AAGAGTGTCTGCGGCAGAGATGCCTCAGACAAGAAAGCACACACTCACGTCAGGCTTCCAAACGAAGCACACAATTGCATGGATAAAATG
ACCGCTGTCTACGCCAACATCCTGTCGGATTCCTACTGGTCAGGCCTGGGCCTTGGCTTCAAGCTGTCCAATAGTGAGAGGAGGAACTGT
GACACCCGAAACGGCAGCAACAAGAGTGATTTTGATTGGCACCAAGACGCTCTGTCCAAAAGCCTGCAGCAGAACTTGCCTTCTCGGTCC
GTCTCGAAACCCAGCCTGTTCAGCTCGGTGCAGTTGTACCGACAGAGCAGCAAGATGTGCGGGACTGTGTTCACAGGGGCCAGCAGATTC
CGATGCCGACAGTGCAGCGCGGCCTATGACACCCTAGTCGAGCTGACTGTGCACATGAATGAAACGGGCCACTATCAAGATGACAACCGC
AAAAAGGACAAGCTCAGACCCACGAGCTATTCAAAGCCCAGGAAAAGGGCTTTCCAGGATATGGACAAAGAGGATGCTCAAAAGGTTCTG
AAATGTATGTTTTGTGGCGACTCCTTTGATTCCCTCCAAGATTTGAGCGTCCACATGATTAAAACAAAACATTACCAAAAAGTGCCTTTG
AAGGAGCCAGTCCCAACCATTTCCTCGAAAATGGTCACCCCGGCTAAGAAACGCGTTTTTGATGTCAATCGGCCGTGTTCCCCCGATTCA
ACCACAGGATCTTTTGCAGATTCTTTTTCTTCTCAGAAGAACGCCAACTTGCAGTTGTCCTCCAACAACCGCTATGGCTACCAAAATGGA
GCCAGCTACACCTGGCAGTTTGAGGCCTGCAAGTCCCAGATCTTAAAGTGCATGGAGTGTGGGAGCTCCCATGACACCTTGCAGCAGCTC
ACCACCCACATGATGGTCACAGGTCACTTTCTCAAGGTCACCAGCTCTGCCTCCAAGAAAGGGAAGCAGCTGGTATTAGACCCGTTAGCA
GTGGAGAAAATGCAGTCGTTGTCTGAGGCCCCAAACAGTGATTCTCTGGCTCCCAAGCCATCCAGTAACTCAGCATCAGATTGTACAGCC
TCTACAACTGAGTTAAAGAAAGAGAGTAAAAAAGAAAGGCCAGAGGAAACCAGCAAGGATGAGAAAGTCGTGAAAAGCGAGGACTATGAA
GATCCTCTACAAAAACCTTTAGACCCTACAATCAAATATCAATACCTAAGGGAGGAAGACTTGGAAGATGGCTCAAAGGGTGGAGGGGAC
ATTTTGAAATCTTTGGAAAATACTGTCACCACAGCCATCAACAAAGCCCAAAACGGGGCCCCCAGCTGGAGTGCCTACCCCAGCATCCAC
GCAGCCTACCAGCTGTCTGAGGGCACCAAGCCGCCTTTGCCTATGGGATCCCAGGTACTGCAGATCCGGCCTAATCTCACCAACAAGCTG
AGGCCCATTGCACCAAAGTGGAAAGTGATGCCACTGGTTTCTATGCCCACACACCTGGCCCCTTACACTCAAGTCAAGAAAGAGTCAGAA
GACAAAGATGAAGCGGTGAAGGAGTGTGGGAAAGAAAGTCCCCACGAAGAGGCCTCATCTTTCAGCCACAGTGAGGGCGATTCTTTCCGC
AAAAGTGAAACACCTCCAGAAGCCAAAAAGACCGAGCTGGGTCCCCTGAAGGAGGAGGAGAAGCTGATGAAAGAGGGCAGCGAGAAGGAG
AAACCCCAGCCCCTGGAGCCCACATCTGCTCTGAGCAATGGGTGCGCCCTCGCCAACCACGCCCCGGCCCTGCCATGCATCAACCCACTC
AGCGCCCTGCAGTCCGTCCTGAACAATCACTTGGGCAAAGCCACGGAGCCCTTGCGCTCACCTTCCTGCTCCAGCCCAAGTTCAAGCACA
ATTTCCATGTTCCACAAGTCGAATCTCAATGTCATGGACAAGCCGGTCTTGAGTCCTGCCTCCACAAGGTCAGCCAGCGTGTCCAGGCGC
TACCTGTTTGAGAACAGCGATCAGCCCATTGACCTGACCAAGTCCAAAAGCAAGAAAGCCGAGTCCTCGCAAGCACAATCTTGTATGTCC
CCACCTCAGAAGCACGCTCTGTCTGACATCGCCGACATGGTCAAAGTCCTCCCCAAAGCCACCACCCCAAAGCCAGCCTCCTCCTCCAGG
GTCCCCCCCATGAAGCTGGAAATGGATGTCAGGCGCTTTGAGGATGTCTCCAGTGAAGTCTCAACTTTGCATAAAAGAAAAGGCCGGCAG
TCCAACTGGAATCCTCAGCATCTTCTGATTCTACAAGCCCAGTTTGCCTCGAGCCTCTTCCAGACATCAGAGGGCAAATACCTGCTGTCT
GATCTGGGCCCACAAGAGCGTATGCAAATCTCTAAGTTTACGGGACTCTCAATGACCACTATCAGTCACTGGCTGGCCAACGTCAAGTAC
CAGCTTAGGAAAACGGGCGGGACAAAATTTCTGAAAAACATGGACAAAGGCCACCCCATCTTTTATTGCAGTGACTGTGCCTCCCAGTTC
AGAACCCCTTCTACCTACATCAGTCACTTAGAATCTCACCTGGGTTTCCAAATGAAGGACATGACCCGCTTGTCAGTGGACCAGCAAAGC
AAGGTGGAGCAAGAGATCTCCCGGGTATCGTCGGCTCAGAGGTCTCCAGAAACAATAGCTGCCGAAGAGGACACAGACTCTAAATTCAAG
TGTAAGTTGTGCTGTCGGACATTTGTGAGCAAACATGCGGTAAAACTCCACCTAAGCAAAACGCACAGCAAGTCACCCGAACACCATTCA
CAGTTTGTAACAGACGTGGATGAAGAATAGCTCTGCAGGACGAATGCCTTAGTTTCCACTTTCCAGCCTGGATCCCCTCACACTGAACCC
TTCTTCGTTGCACCATCCTGCTTCTGACATTGAACTCATTGAACTCCTCCTGACACCCTGGCTCTGAGAAGACTGCCAAAAAAAAAAAAA
AAAAAAAATCACCCCAGCCATTTCTCTTCATCCTCACTAACAATTTGGTAATGAAGTATTGATTTCCACTTCTCTGCTTATGGGCGGTAT
TAGATTTTCATTGATAAATTGCAATGGGGCTGTCTCGTCTCCACAGTACCCTTTTCACTGTCACAAGAAAACAAAGTGCCACCGAAGAAA
AGTAATGACTGAGAGCATTGATGTACTTATTTTGTCAGTTTGTAACAGGAAAGTGGGGGGGAGTCTAAGTCTTCATAGTCTAATGTCCAA
GTGGGTTGCACTAGATGTAGACACTTGGAGGCTTACTTTTCATGGTAATGTCCATTTCCTATTTATAACCCCTCTGGGAACGTTTGTCTA
AAGGAAATGTTTCTGTTCAGTGTAACAATTACAGTTGCACCTGGATTGCCCAGTCCTGCCCCTGCACTAGGGGACCATTAATCACTGCAA
AGTAGAAGAATTATTAAGTTAAACCAGAGTTTGAGCCAAGAAAACCCCTGAACAATGTTCATCTTCTGTGAAACTTGCTCAAATAGTTAA
GCTTAACCATGTTGCTGCCAAAGACTTTTCCTATGCAGTGGTGGGGCACCTTGATCATCATCATTATCTTGATTGGCTGAAAAAAAAATA
GTTTTAAGCACACACCACTGTCTATGAGAACTGCAAATTGGGAGAATAGGTGAAATGCAGAATCTGAGAGAACGCGAGAAGATGAGATCA
TTACAGGGTGGAAAGTTCTGCAGCAGCCTTTTCTGGTAATCCCTTTCTGCAGAACCTGATGTTTATGGGCTCTAAAACGCAGCTTAGCTT
TAGAAGCAACAGAAAGCATGAAATAGGGTGTCCATTTTAAATGTGTTCCTGCAACTTTTTTCATTAAAACTTTGAGGGCCCAATTTTAAT
TTGTGGAATATTCCCGTTAATAATGAGATCTAATTAAGACATCCATTAAAAGCCCGTTAAAGTTAATTTAACGTAAAAATTCCAATAGAA
CTGTATTAGATTTTCTCCATTAAATTAACGTTATGGATTTTTAACGGATGTCTTAATTATACGTTATTATTAACGGGAATACTGTATTAC
ACAGATTAAAATCAGGTCCTAAGTCAACTTGGAAGAGCTAAGAGCATGTTTTAATATTAAAAGTCTTGCATACCTAGTGCACAGTTTGGA
GACGCAAGGATAGATCTGTTTACTCTAGTTGAACATTTTCTATACAATTGAAAGCAACCTATAATAGATAAATCCATCATTGCATTTAAA
CAATGAATTTCCTTATTCTCAAAGGACAAATACGTCTGGATTATGTGGTAAATTGCTACTCAGCTATGGTGAAATATTTATACTATTCTA
GGCACAACACTAGGAACTAGGTGATTCTGAAACAAAAGGAATATTTTCTGTTGTTGCTTTAATTACCAAGGTTATTTTTTTTTAATCTCA
ACACTGACAAAATGAAACCAAATATCTCTTCCTCACCATTTCTCAAGGAGGCTGCCTGTTGGAATTGTTTTGGAAATTTTGACATGATCC
CTAAATTCAACATTGGGATTAAAAAAAAAAAAAAACTTCTTATTTACCTCCTAGGGAAAGTGTTGCCCTTATGCCACATATAATAGCAAA
TTGCTTTTTTTATGGCATGCATAACCTAGATGGGAAAAAATATGGCGCTTCGGGGAAGGAGGGAAAAAGTAAATGAAGTTCCAGGAATGT
CATTCTGAAGTAATGAGGCATGGACAGAAAATATACCCCTCACATCATCGGATTGAGATGGCAGTCGAAATAGCTTCATTGAAGTGTCAG
CACTCATCCATCAATCAATCACCCACAAGGAAAAATAGCAACAGTACAACGGGGTGGCTTTTATGGGATTTACTCATGGGCATAGGGAAT
AGCGGCTCAAATGTAGTTCTGACATGAAAAGCAAGGTGCTGATATTATTTTTTATGATGGGAGGATCATAAAGTGAATTGAGAACAGTGA
GGTCTGTCTTTGCTTAACCTATTCAACCAGAAATGAATGGAGCTCGACTGGAAAGGAACAGTCTTCAGATGGGTTAAGATTGAAGGGTGG
ACTGGACTCTACTGAGCACCGTCCTTCAACAAGGAAATTCTATTAAAGGAAAATCAATGCATTAGTATTGGGGTTCTCGTAGCTGTTAAA
AATTGTCTGCTCCAATCCAGGGTTATTAGGCCAAAGTTACATAATTCAGATCTCACTGCAACCATCCAAAAGTGGATTCTCGAGCCCTTG
CTCCAATGGGGGGAGGAGATCAATACAATTCCCAATTCCATGGAAATTGTTTCCCTTCTAAGGAAGAAAAAATAAATCATCTGCTTCAAC
ATATAATCGATATGGTTTTGTTAGCGTAATTTCTATGGTGGGTGGGGTGGGAGGTGAGAGAAAAAAATATTGATAAATTTGGTAAGACAG
GTGAATTGCCGCCTGGCAACCGTGCATGTCACTGCCGAGGGATGGCTGCTAAGGTTCACCTTAGAAAACAAGATCTGGGCTGGCACTGGG
GCATACATCACCACTCAGCATATTCCTAGAGGCCAGGCCTGTCTTCACTCAGCCAGCCCTCTGAGGCTTCTAGAAACTTCTTTCTGGAGG
AAAAAAACTAAATAACATAAACTCAGGAGAATGTCTTTACCCACCTTCATACCACTGCTTTCTTTTTGCTGAATAAAACACAGTTCTGAT
AAGTAAGAACTTTAGAATTGGAAAGGAGGCTGACATGCAAATATAATGCAAATTACCCTCAAGTATCGCCATTCTTCCACCACCTCTTGG
TACCAGTGAGAGCGAGAGATTGCCTTTTCTTCCCCATCCCTCCTTCCAGCTAAGACCACCAACCAGCTGCAAATTGAGATGTCCATTTAA
AAATTTATATGTCAATATTTAAATGTTACATATTTGGCCCTATTTTGTAGTTCAGCAAATCCTCCAAATACACAGCATGTTACAAGGCAC
TGGTGGCACAGGGCACAACAGGAAATGATATTTATTTAGCAAATTCATTTAACAAATATTATTGGGCACCTGTTATGTGAGACACTGTCC
TAGGCACTGTGGGATAACAACAGCAAACACTTCACACAACAGCCTGGCCTTCCTGTGTTTTACAACAGCTCCTAAAGATAGCTGATATCA
AGACATTTGAGGGACACAGTTCATGTAGAATCAAAATATTAGTATTTCAGAATAAGGATTTTTTTTCTGAAAAGCATACAGAGAGGAAAC
AGCTTAAAAATAGGTCAAGACCTAAAAACAGAATATAATCACGGAATAAACTGGATAACCCAGACAGTCCCCACAGAATTTCTTTCAGGT
CACAGATTTCTTAAAACTCACCCCCAAAATGTGCCTGCTTGGTTGTTTGAATCTTGCATAATTAATGTCACAGGCGCAAGCCGCTGAACT
TAGTTGAGATGCAGAAAACAAACAAATGCAATGACATATCTGAGAAGCATTTATGTAACTCCGGTTAAGTGGTGAGGAGGGGTGTGTGAA
GACAGTGTGCATGCATGAGTGTGTATTCATATATATGTGTATACATATGAATTTCACTGTTATTTTCCAGGGTCTATGGACAATGTGGCA
GTAAGAGTCTATGATGTTCTGAAACTTTTCACAGTAAATCCAAAGATTACAGACCTTACAAGGTGCTTGCATTCTGTTGCTTTTCCATCT
GTCACTTCTCAGGTTATTTGACTGTGTTCAAACCTTCTTTTCTTTTTCATTGAGTTTCATTTTTTAAGCTTGTTAAATGCTTTTGTTTAA
AAAAAAAAAAAAAACCCCAAATGTCATTTTTCACATTATCCTCTCTTCTCTGCAACAAGGATAGTAAGATGTAGATGAATGCAAAAATAA
TAACAACAATAAGGAAATATATTAAAGCTTTAAAATATGCACATATGTAGTTCTAAAGAGCAATAACGGTAGTATCTATTTCGAACATGC
ATTAGGCAAAAAAGAAATCAAAACTGAAATTTTCGTGTATTTTTCCCCTTGTAAGATGTTCAAATGCTAACTTCATTTTCTCCTTTCCTC
TATGTGGCACTTTCTCAAAATATCTATGAAATACTTTTAGACAAAGATTGAGCTGGAGAAAGAGATACAAATTTCCATCCCCCCAGACAG
AGAGACATATTTCCATTGTAGGAAGGCATTAAACATTTTGAAACTTGTGAATCATCTTTAGAATTTCTACTGGGGAATTTTACTTCTTCA
TCCAAAGTAAAAGCCACTTATCTCCTTTGGTTCCCAGTGACAGATTCAGAGGCATACGCAGATATACAATTTTCAGGCTCTAGTTAATCT
TCTTCCAATAGTTACGAACAATGGGCTAACAGGCGTGGGTGTTTCTCCAAAAATTATTCATGCACAAGGCAGCCCAAAGCTTCAGGGAAA
ACTAGAAATGTGTTATGGATTAGAATAGGACTGTTTTAAAATGCTAGTACCAGGTGGAACGCTATTTCTGCAACAGGACTCTGTCCATTT
CCTTTGGAACAATATATTCCAAGTAAAATGGCTCTTCCAAGGAATGACACCTTTACTTGACACCCTTCGGCATACAAATGATTTTACCAA
TAGCCATGATTATTATTAAGGCCTTTTAAAATACAGGCTGTTTGAAAAAAGACAGATTAAATATTCACAGCCTTTGTATCATGGTTATTT
GCTTAAAACAGCTTTTAGAAGTACAAGTAATAACTTTTTGATAAGAAACCCCAGGAGAAACTTTTTGGTAAGAAACCTCAAAAAATTTGA
ACAAAGGCATTACAAAAAAAAAAAAAAAACTAACCACTCCATTCAACTCTCTCAGAAAATAAATTTCAATGTGTTCAATGAATTGTCTTG
AACCTGAAACCTGCATTTAGATATCAGTCCCCTGCCAATAGCTAATATTAACAGAATTTGAACAATCATACAATTATGTCTCAAATGTGA
AGACTTTGTACAGTAATATTTTCACTTTCTAAATGACCCATATAACATTCAGGAATTATAGATGTGTATGTATATTTTTTAAGTACAGAA
AGTTCAGCCAGTCTTCAGAGAAGTAAAAGTGATGTCTATTGTGCATTGAAGTAAATATTACAAACATTCCAGTTTCGCAATACAATACTT
GAGCTTTCGAACACCTCAGACACTAGAATGTGTAATGCGAGTCAAAAAAGCTGACATACAAAACAATTCCCATTTGGCTCAGGGTTCCTA
AATGTCACAATATCTTGGGTAAAATATACTTTTTGATTTCCTGATGATGTCCTTCTAATCCCTTCTGACTTTGATTCCTAACAGCCAGGC
ACTGTTGACATGAATCATTAACTTCCAAACCCCTTTAAAATCAAGAAGCTAGGTGATCATACAGTCATTTCAATGGCCAACCAGTTCTTG
CTCTACAGAGCTTTTACACCTTTTTGGGAAACCTGATATCAAACACATTTATGTTATATATTTGCTCCCTTGCATTAATTCTAGATTTTT
TTTTAATTTCTTTTAGAAAGGGCAGGGGGGAAGTGGGTCAGAGCAAGGTTCAAGAATCACATTCATCCTTGCTCTAAAGTGTTTACTTGC
CAGCAAAGAAAGGCAAACACATTTTTATATTCAGAAAGCAGACCGGTCATTTTCAAAGAAAAATGACTGCAACCATGCCTGTAGAATGTT
TCTGTGCAAGCGCACTAATTTTCTATCACCTGCATGCTGTATATAATACATTTGCCTGTATACTAGGAAGAAAAACCAGGCTGTTTTCCC
TGAGTACAATGCAGCTTGGATGGCTGGGAGCGTAAGCCTTCCGTGCATTTTTATAGTGTACATATTTGTATATACTAACTATATCGCCAT
GTATGAACACAGATTTTGTTATATTTGCTTGTTTCTGTTTCCTACCAAACTGGCCCACAATGGGGATTCTTTTGTATAGAAAAAATATGC
TTGTAATTTTTTCCTGGTCATTCTCTTTCAATAGCTTATGAAAGAATTAGATCTGAGTTTACAAAGAAACTATAAGAACCAAGTTTGTCT
GTCTGCATGAGTCCCGTCCAATTGCTGGATCTAGGGAGGAACCAACTTCCTAATTCAGAGTTTTCCTTTTAAAGGCATGCTTTACCCCCA
TGGGAAAACTGCACACTCATCCATGTAGAATTATTCTCTTTGTATTTTATCTAATAGTGCCTGAAAATTTTTTTAATGTCTTCTTAGAAG
AAGAATTCATAATTGTCAAAATTTGAAACATTAGCTTAATTTTGTTTTTATGACCTCAAGATTCTTCTCCTTATTTATTCGGTTGCTGTT
GTAATGGGGCCCCAGGCCATTCCTGACATCGGCGTGTTCTTCTTCTGCATTAAGGATGTTTTTGAAATTACAGAGATTATTGAGCCAACA
GGCTGTTTTAATCAAAACCATGTTTCACTTCTTTTTGATGATTATAAATTGTCCTTGCAATGAAAAAAAAAAAAGAACTTTTCTGCTAGG
AAGATTATACCACCCTGTGGCCAAACAGATTCATCACAGATAGGCATCTATGCCCATTTCTCTGGGATCTGGAAAATTCTTCCCTTGGCT
GACCCCAATTTCTTTTACTCCCCATTATCCTGAATATTAGCTTTCAATGCAGTCACTATTTGACATTTCCAAAGGCTTTGCCGCATTGTC
ACTGCCCAAAGACAAACAACCACTGGAAATGATGGCTTTCCTGCTTGAAACGAAGGGGGCCAGGTGCAGTGGCTCAAGCCTGTAACCCCT
GCACTTTGGAAGGCTGAGGCAGGCGGATCACTTGAGGTCAGGAGTTTCAGACCAACCTGGCCAACATGGCAAAACCTCGTCTCTACTAAA
AATACAAAAAACATTAGCAGGGCATGGTGGTGCGTGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAAGAGAATTGCTTGAGCCCGGG
AGGCGAAGGTTGCAGTGAGCTGAGATGGTGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTGTGTCTCAAAAAAAAAAAAAAGAAT
GGATTTTCAGAAAAAGTGCTCCCTTTCCTGTCCTGTGGTGCCACCATCCTGTCCTCCTTCGTAATCATGAACAATCTGATCTTGAACTCC
CACATAACTTAAATCAGGCAAAAAGAAACATTCACAGCGTCCCCTTGCTGAATAAAAATGACTTTGTTTGGAGGCACTTAAGATGTATGC
CTGTGTGTGGTGCCGCAGCATTGAAATTATCTGTAGAAGGGGAATTTTTTTTAAAAATACAATTTTATCACTAGAAATAAATTCCGATGG
TGGAAACGAAGAAAACCCTTAAATTATATCACAAAAGCCATTATTTTTTGCATCCAAAGAGTTTTTTTTTTTAAGGAAAATCATTCTACT
TTGAGAACTGTAATTAAAGCCCTAAATAACAGACACTACTTTGTTGAGCTATTGTGAAAAAAAAACAACACATTCGCCAAGGTTATATGG
AGCCCCTGATTTCCATCAAAAAGGTTTCTATAAGTATATTATTTACATTTTTATACATGATAACTCTTGCCTTTGTGTTGAAAAAAAAAA
AGTCTCTTTTTTTTCCCCCACTCAGCAGTTATTGGAAATAGACTGTTCCCATCTGAAACCGTATCGTAATTTGCATCAGGAAACCCAACT
GCTGACATTGAGGACCTGGGTGTGTTCAATTATGATTTTGCTGGAGGCTGTCCCTCATTTTAATGCTGCAGCTATTGAACCACCTTCCTG
AAACCTAGCTGATACGGAATAGCAGAGACATGCCTCTCAACACCATTAGCTTTGCAAATGGCTTCATTTCAGTCAACGTCGACTTCTGCT
TTGGCCAATTGAAAAATGAAAATTAAAGGAGAGAAGAAAAAAAACACAGATGCACTTAAAACATGAAAAGAATTATTTATATGATAAAAA
TATATTTAGCTTTTCAAAGCACAAGACTGAATAGAAGTGCTCTTTTTATGCTTTCTGGAGATGTTACTGTTAAATGTCTTTCTACATCAG

>20353_20353_7_CTNNBL1-TSHZ2_CTNNBL1_chr20_36431450_ENST00000405275_TSHZ2_chr20_51870038_ENST00000371497_length(amino acids)=1398AA_BP=377
MRRKQTGTRERGRYREEEMTVVEEADDDKKRLLQIIDRDGEEEEEEEEPLDESSVKKMILTFEKRSYKNQELRIKFPDNPEKFMESELDL
NDIIQEMHVVATMPDLYHLLVELNAVQSLLGLLGHDNTDVSIAVVDLLQELTDIDTLHESEEGAEVLIDALVDGQVVALLVQNLERLDES
VKEEADGVHNTLAIVENMAEFRPEMCTEGAQQGLLQWLLKRLKAKMPFDANKLYCSEVLAILLQDNDENRELLGELDGIDVLLQQLSVFK
RHNPSTAEEQEMMENLFDSLCSCLMLSSNRERFLKGEGLQLMNLMLREKKISRSSALKVLDHAMIGPEGTDNCHKFVDILGLRTIFPLFM
KSPRKIKKVGTTEKEHEGYAQEEQLKEEEEIKEEEEEEDSGSVAQLQGGNDTGTDEELETGPEQKGCFSYQNSPGSHLSNQDAENESLLS
DASDQVSDIKSVCGRDASDKKAHTHVRLPNEAHNCMDKMTAVYANILSDSYWSGLGLGFKLSNSERRNCDTRNGSNKSDFDWHQDALSKS
LQQNLPSRSVSKPSLFSSVQLYRQSSKMCGTVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNRKKDKLRPTSYSKPRKRAFQDM
DKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNRPCSPDSTTGSFADSFSSQKNANLQLSS
NNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLAVEKMQSLSEAPNSDSLAPKPS
SNSASDCTASTTELKKESKKERPEETSKDEKVVKSEDYEDPLQKPLDPTIKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAP
SWSAYPSIHAAYQLSEGTKPPLPMGSQVLQIRPNLTNKLRPIAPKWKVMPLVSMPTHLAPYTQVKKESEDKDEAVKECGKESPHEEASSF
SHSEGDSFRKSETPPEAKKTELGPLKEEEKLMKEGSEKEKPQPLEPTSALSNGCALANHAPALPCINPLSALQSVLNNHLGKATEPLRSP
SCSSPSSSTISMFHKSNLNVMDKPVLSPASTRSASVSRRYLFENSDQPIDLTKSKSKKAESSQAQSCMSPPQKHALSDIADMVKVLPKAT
TPKPASSSRVPPMKLEMDVRRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTI
SHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQMKDMTRLSVDQQSKVEQEISRVSSAQRSPETIAA

--------------------------------------------------------------
>20353_20353_8_CTNNBL1-TSHZ2_CTNNBL1_chr20_36431450_ENST00000405275_TSHZ2_chr20_51870038_ENST00000603338_length(transcript)=4784nt_BP=1375nt
TGACGGGCCCGCGGTCTGGGCGTGAGTGCAGGGAAGTGGAGTATTTGCTGGGCCGGGTACCATGGACGTGGGCGAACTTCTGAGCTACCA
GGGGCATGGATGGAGACACGCACACACACAGGCAATAGGCCTCAAGATTATTGGCGAGTAAAGGCATCTATCTATTATCGTGAAGCCTAC
TCTGAGCTTTGACCCAATAGGGGCACAAAACGTCCCCGGGATGATGAAGAGGAGGAGCAGAAGATGCGTCGGAAACAAACTGGTACTCGA
GAACGCGGCCGCTATCGGGAAGAAGAAATGACTGTGGTGGAGGAAGCGGATGATGACAAAAAAAGGCTGCTGCAGATTATTGACAGAGAT
GGGGAAGAGGAAGAGGAAGAGGAGGAGCCATTGGATGAAAGCTCAGTGAAGAAAATGATCCTCACATTTGAAAAGAGATCATATAAAAAC
CAAGAATTGCGGATTAAGTTTCCAGACAATCCAGAGAAGTTCATGGAATCCGAGCTGGACCTAAATGACATCATTCAGGAGATGCACGTG
GTGGCCACCATGCCAGACCTGTACCACCTTCTGGTGGAGCTGAATGCTGTACAGTCGCTTCTCGGCTTGCTCGGACACGATAATACAGAT
GTGTCCATAGCTGTGGTCGATTTGCTTCAGGAATTAACAGATATAGACACCCTCCATGAGAGTGAAGAGGGAGCAGAAGTGCTCATCGAT
GCTCTGGTGGATGGGCAGGTGGTAGCACTGCTGGTACAGAATCTGGAGCGCCTGGATGAGTCTGTGAAAGAGGAGGCAGATGGCGTCCAC
AACACTCTGGCTATTGTGGAAAACATGGCTGAGTTCCGGCCTGAGATGTGTACAGAGGGTGCCCAGCAGGGTCTTCTACAGTGGCTGTTG
AAGAGGCTGAAGGCAAAGATGCCTTTTGATGCCAACAAACTGTATTGCAGTGAAGTGCTGGCCATATTGCTCCAGGACAATGATGAAAAC
AGGGAATTGCTTGGGGAGCTGGATGGAATCGATGTGCTTCTTCAGCAGTTATCCGTGTTTAAAAGACACAATCCCAGCACGGCTGAGGAG
CAGGAGATGATGGAGAATCTGTTTGATTCCCTCTGCTCCTGTCTAATGCTTAGTTCCAATCGTGAGCGCTTCCTGAAGGGCGAGGGTCTT
CAGCTGATGAATCTCATGCTCAGGGAAAAGAAGATCTCCCGGAGCAGTGCCCTGAAAGTGCTGGACCATGCCATGATTGGCCCCGAAGGC
ACAGACAACTGCCATAAGTTTGTTGACATTCTTGGCTTACGAACCATCTTTCCCCTCTTTATGAAATCTCCCAGGAAGATCAAGAAAGTG
GGAACCACTGAGAAGGAACATGAAGGCTACGCCCAGGAGGAACAGCTGAAAGAAGAGGAGGAAATAAAAGAAGAGGAGGAGGAGGAGGAC
AGCGGTTCAGTAGCTCAACTGCAGGGTGGCAATGACACAGGGACGGACGAGGAGCTAGAAACGGGCCCAGAGCAAAAAGGCTGCTTCAGC
TACCAGAACTCTCCAGGAAGTCATTTGTCCAATCAGGATGCCGAGAACGAGTCTCTGCTGAGTGACGCCAGTGATCAGGTGTCGGACATC
AAGAGTGTCTGCGGCAGAGATGCCTCAGACAAGAAAGCACACACTCACGTCAGGCTTCCAAACGAAGCACACAATTGCATGGATAAAATG
ACCGCTGTCTACGCCAACATCCTGTCGGATTCCTACTGGTCAGGCCTGGGCCTTGGCTTCAAGCTGTCCAATAGTGAGAGGAGGAACTGT
GACACCCGAAACGGCAGCAACAAGAGTGATTTTGATTGGCACCAAGACGCTCTGTCCAAAAGCCTGCAGCAGAACTTGCCTTCTCGGTCC
GTCTCGAAACCCAGCCTGTTCAGCTCGGTGCAGTTGTACCGACAGAGCAGCAAGATGTGCGGGACTGTGTTCACAGGGGCCAGCAGATTC
CGATGCCGACAGTGCAGCGCGGCCTATGACACCCTAGTCGAGCTGACTGTGCACATGAATGAAACGGGCCACTATCAAGATGACAACCGC
AAAAAGGACAAGCTCAGACCCACGAGCTATTCAAAGCCCAGGAAAAGGGCTTTCCAGGATATGGACAAAGAGGATGCTCAAAAGGTTCTG
AAATGTATGTTTTGTGGCGACTCCTTTGATTCCCTCCAAGATTTGAGCGTCCACATGATTAAAACAAAACATTACCAAAAAGTGCCTTTG
AAGGAGCCAGTCCCAACCATTTCCTCGAAAATGGTCACCCCGGCTAAGAAACGCGTTTTTGATGTCAATCGGCCGTGTTCCCCCGATTCA
ACCACAGGATCTTTTGCAGATTCTTTTTCTTCTCAGAAGAACGCCAACTTGCAGTTGTCCTCCAACAACCGCTATGGCTACCAAAATGGA
GCCAGCTACACCTGGCAGTTTGAGGCCTGCAAGTCCCAGATCTTAAAGTGCATGGAGTGTGGGAGCTCCCATGACACCTTGCAGCAGCTC
ACCACCCACATGATGGTCACAGGTCACTTTCTCAAGGTCACCAGCTCTGCCTCCAAGAAAGGGAAGCAGCTGGTATTAGACCCGTTAGCA
GTGGAGAAAATGCAGTCGTTGTCTGAGGCCCCAAACAGTGATTCTCTGGCTCCCAAGCCATCCAGTAACTCAGCATCAGATTGTACAGCC
TCTACAACTGAGTTAAAGAAAGAGAGTAAAAAAGAAAGGCCAGAGGAAACCAGCAAGGATGAGAAAGTCGTGAAAAGCGAGGACTATGAA
GATCCTCTACAAAAACCTTTAGACCCTACAATCAAATATCAATACCTAAGGGAGGAAGACTTGGAAGATGGCTCAAAGGGTGGAGGGGAC
ATTTTGAAATCTTTGGAAAATACTGTCACCACAGCCATCAACAAAGCCCAAAACGGGGCCCCCAGCTGGAGTGCCTACCCCAGCATCCAC
GCAGCCTACCAGCTGTCTGAGGGCACCAAGCCGCCTTTGCCTATGGGATCCCAGGTACTGCAGATCCGGCCTAATCTCACCAACAAGCTG
AGGCCCATTGCACCAAAGTGGAAAGTGATGCCACTGGTTTCTATGCCCACACACCTGGCCCCTTACACTCAAGTCAAGAAAGAGTCAGAA
GACAAAGATGAAGCGGTGAAGGAGTGTGGGAAAGAAAGTCCCCACGAAGAGGCCTCATCTTTCAGCCACAGTGAGGGCGATTCTTTCCGC
AAAAGTGAAACACCTCCAGAAGCCAAAAAGACCGAGCTGGGTCCCCTGAAGGAGGAGGAGAAGCTGATGAAAGAGGGCAGCGAGAAGGAG
AAACCCCAGCCCCTGGAGCCCACATCTGCTCTGAGCAATGGGTGCGCCCTCGCCAACCACGCCCCGGCCCTGCCATGCATCAACCCACTC
AGCGCCCTGCAGTCCGTCCTGAACAATCACTTGGGCAAAGCCACGGAGCCCTTGCGCTCACCTTCCTGCTCCAGCCCAAGTTCAAGCACA
ATTTCCATGTTCCACAAGTCGAATCTCAATGTCATGGACAAGCCGGTCTTGAGTCCTGCCTCCACAAGGTCAGCCAGCGTGTCCAGGCGC
TACCTGTTTGAGAACAGCGATCAGCCCATTGACCTGACCAAGTCCAAAAGCAAGAAAGCCGAGTCCTCGCAAGCACAATCTTGTATGTCC
CCACCTCAGAAGCACGCTCTGTCTGACATCGCCGACATGGTCAAAGTCCTCCCCAAAGCCACCACCCCAAAGCCAGCCTCCTCCTCCAGG
GTCCCCCCCATGAAGCTGGAAATGGATGTCAGGCGCTTTGAGGATGTCTCCAGTGAAGTCTCAACTTTGCATAAAAGAAAAGGCCGGCAG
TCCAACTGGAATCCTCAGCATCTTCTGATTCTACAAGCCCAGTTTGCCTCGAGCCTCTTCCAGACATCAGAGGGCAAATACCTGCTGTCT
GATCTGGGCCCACAAGAGCGTATGCAAATCTCTAAGTTTACGGGACTCTCAATGACCACTATCAGTCACTGGCTGGCCAACGTCAAGTAC
CAGCTTAGGAAAACGGGCGGGACAAAATTTCTGAAAAACATGGACAAAGGCCACCCCATCTTTTATTGCAGTGACTGTGCCTCCCAGTTC
AGAACCCCTTCTACCTACATCAGTCACTTAGAATCTCACCTGGGTTTCCAAATGAAGGACATGACCCGCTTGTCAGTGGACCAGCAAAGC
AAGGTGGAGCAAGAGATCTCCCGGGTATCGTCGGCTCAGAGGTCTCCAGAAACAATAGCTGCCGAAGAGGACACAGACTCTAAATTCAAG
TGTAAGTTGTGCTGTCGGACATTTGTGAGCAAACATGCGGTAAAACTCCACCTAAGCAAAACGCACAGCAAGTCACCCGAACACCATTCA
CAGTTTGTAACAGACGTGGATGAAGAATAGCTCTGCAGGACGAATGCCTTAGTTTCCACTTTCCAGCCTGGATCCCCTCACACTGAACCC
TTCTTCGTTGCACCATCCTGCTTCTGACATTGAACTCATTGAACTCCTCCTGACACCCTGGCTCTGAGAAGACTGCCAAAAAAAAAAAAA
AAAAAAAATCACCCCAGCCATTTCTCTTCATCCTCACTAACAATTTGGTAATGAAGTATTGATTTCCACTTCTCTGCTTATGGGCGGTAT
TAGATTTTCATTGATAAATTGCAATGGGGCTGTCTCGTCTCCACAGTACCCTTTTCACTGTCACAAGAAAACAAAGTGCCACCGAAGAAA

>20353_20353_8_CTNNBL1-TSHZ2_CTNNBL1_chr20_36431450_ENST00000405275_TSHZ2_chr20_51870038_ENST00000603338_length(amino acids)=1398AA_BP=377
MRRKQTGTRERGRYREEEMTVVEEADDDKKRLLQIIDRDGEEEEEEEEPLDESSVKKMILTFEKRSYKNQELRIKFPDNPEKFMESELDL
NDIIQEMHVVATMPDLYHLLVELNAVQSLLGLLGHDNTDVSIAVVDLLQELTDIDTLHESEEGAEVLIDALVDGQVVALLVQNLERLDES
VKEEADGVHNTLAIVENMAEFRPEMCTEGAQQGLLQWLLKRLKAKMPFDANKLYCSEVLAILLQDNDENRELLGELDGIDVLLQQLSVFK
RHNPSTAEEQEMMENLFDSLCSCLMLSSNRERFLKGEGLQLMNLMLREKKISRSSALKVLDHAMIGPEGTDNCHKFVDILGLRTIFPLFM
KSPRKIKKVGTTEKEHEGYAQEEQLKEEEEIKEEEEEEDSGSVAQLQGGNDTGTDEELETGPEQKGCFSYQNSPGSHLSNQDAENESLLS
DASDQVSDIKSVCGRDASDKKAHTHVRLPNEAHNCMDKMTAVYANILSDSYWSGLGLGFKLSNSERRNCDTRNGSNKSDFDWHQDALSKS
LQQNLPSRSVSKPSLFSSVQLYRQSSKMCGTVFTGASRFRCRQCSAAYDTLVELTVHMNETGHYQDDNRKKDKLRPTSYSKPRKRAFQDM
DKEDAQKVLKCMFCGDSFDSLQDLSVHMIKTKHYQKVPLKEPVPTISSKMVTPAKKRVFDVNRPCSPDSTTGSFADSFSSQKNANLQLSS
NNRYGYQNGASYTWQFEACKSQILKCMECGSSHDTLQQLTTHMMVTGHFLKVTSSASKKGKQLVLDPLAVEKMQSLSEAPNSDSLAPKPS
SNSASDCTASTTELKKESKKERPEETSKDEKVVKSEDYEDPLQKPLDPTIKYQYLREEDLEDGSKGGGDILKSLENTVTTAINKAQNGAP
SWSAYPSIHAAYQLSEGTKPPLPMGSQVLQIRPNLTNKLRPIAPKWKVMPLVSMPTHLAPYTQVKKESEDKDEAVKECGKESPHEEASSF
SHSEGDSFRKSETPPEAKKTELGPLKEEEKLMKEGSEKEKPQPLEPTSALSNGCALANHAPALPCINPLSALQSVLNNHLGKATEPLRSP
SCSSPSSSTISMFHKSNLNVMDKPVLSPASTRSASVSRRYLFENSDQPIDLTKSKSKKAESSQAQSCMSPPQKHALSDIADMVKVLPKAT
TPKPASSSRVPPMKLEMDVRRFEDVSSEVSTLHKRKGRQSNWNPQHLLILQAQFASSLFQTSEGKYLLSDLGPQERMQISKFTGLSMTTI
SHWLANVKYQLRKTGGTKFLKNMDKGHPIFYCSDCASQFRTPSTYISHLESHLGFQMKDMTRLSVDQQSKVEQEISRVSSAQRSPETIAA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CTNNBL1-TSHZ2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CTNNBL1-TSHZ2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CTNNBL1-TSHZ2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource