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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CTSZ-ZHX3 (FusionGDB2 ID:20548)

Fusion Gene Summary for CTSZ-ZHX3

check button Fusion gene summary
Fusion gene informationFusion gene name: CTSZ-ZHX3
Fusion gene ID: 20548
HgeneTgene
Gene symbol

CTSZ

ZHX3

Gene ID

1522

23051

Gene namecathepsin Zzinc fingers and homeoboxes 3
SynonymsCTSXTIX1
Cytomap

20q13.32

20q12

Type of geneprotein-codingprotein-coding
Descriptioncathepsin Zcarboxypeptidase LBcathepsin B2cathepsin IVcathepsin Pcathepsin Xcathepsin Ycathepsin Z1cysteine-type carboxypeptidaselysosomal carboxypeptidase Bpreprocathepsin Pzinc fingers and homeoboxes protein 3triple homeobox 1triple homeobox protein 1zinc finger and homeodomain protein 3
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000217131, ENST00000561291, 
ENST00000309060, ENST00000432768, 
ENST00000540170, ENST00000544979, 
ENST00000557816, ENST00000558993, 
ENST00000559234, ENST00000560361, 
Fusion gene scores* DoF score9 X 9 X 3=2435 X 4 X 4=80
# samples 95
** MAII scorelog2(9/243*10)=-1.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/80*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CTSZ [Title/Abstract] AND ZHX3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCTSZ(57571694)-ZHX3(39813841), # samples:2
Anticipated loss of major functional domain due to fusion event.CTSZ-ZHX3 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
CTSZ-ZHX3 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCTSZ

GO:0032091

negative regulation of protein binding

19433310

TgeneZHX3

GO:0045892

negative regulation of transcription, DNA-templated

12659632


check buttonFusion gene breakpoints across CTSZ (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ZHX3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A0GY-01ACTSZchr20

57571694

-ZHX3chr20

39813841

-
ChimerDB4BRCATCGA-BH-A0GY-01ACTSZchr20

57572658

-ZHX3chr20

39813841

-


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Fusion Gene ORF analysis for CTSZ-ZHX3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000217131ENST00000561291CTSZchr20

57571694

-ZHX3chr20

39813841

-
5CDS-intronENST00000217131ENST00000561291CTSZchr20

57572658

-ZHX3chr20

39813841

-
Frame-shiftENST00000217131ENST00000309060CTSZchr20

57572658

-ZHX3chr20

39813841

-
Frame-shiftENST00000217131ENST00000432768CTSZchr20

57572658

-ZHX3chr20

39813841

-
Frame-shiftENST00000217131ENST00000540170CTSZchr20

57571694

-ZHX3chr20

39813841

-
Frame-shiftENST00000217131ENST00000544979CTSZchr20

57572658

-ZHX3chr20

39813841

-
Frame-shiftENST00000217131ENST00000557816CTSZchr20

57571694

-ZHX3chr20

39813841

-
Frame-shiftENST00000217131ENST00000558993CTSZchr20

57572658

-ZHX3chr20

39813841

-
Frame-shiftENST00000217131ENST00000559234CTSZchr20

57571694

-ZHX3chr20

39813841

-
Frame-shiftENST00000217131ENST00000560361CTSZchr20

57571694

-ZHX3chr20

39813841

-
In-frameENST00000217131ENST00000309060CTSZchr20

57571694

-ZHX3chr20

39813841

-
In-frameENST00000217131ENST00000432768CTSZchr20

57571694

-ZHX3chr20

39813841

-
In-frameENST00000217131ENST00000540170CTSZchr20

57572658

-ZHX3chr20

39813841

-
In-frameENST00000217131ENST00000544979CTSZchr20

57571694

-ZHX3chr20

39813841

-
In-frameENST00000217131ENST00000557816CTSZchr20

57572658

-ZHX3chr20

39813841

-
In-frameENST00000217131ENST00000558993CTSZchr20

57571694

-ZHX3chr20

39813841

-
In-frameENST00000217131ENST00000559234CTSZchr20

57572658

-ZHX3chr20

39813841

-
In-frameENST00000217131ENST00000560361CTSZchr20

57572658

-ZHX3chr20

39813841

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000217131CTSZchr2057571694-ENST00000309060ZHX3chr2039813841-7674920681195375
ENST00000217131CTSZchr2057571694-ENST00000558993ZHX3chr2039813841-1301920681195375
ENST00000217131CTSZchr2057571694-ENST00000544979ZHX3chr2039813841-1295920681195375
ENST00000217131CTSZchr2057571694-ENST00000432768ZHX3chr2039813841-1206920681195375
ENST00000217131CTSZchr2057572658-ENST00000540170ZHX3chr2039813841-683975715725236
ENST00000217131CTSZchr2057572658-ENST00000559234ZHX3chr2039813841-384475715725236
ENST00000217131CTSZchr2057572658-ENST00000557816ZHX3chr2039813841-113875715725236
ENST00000217131CTSZchr2057572658-ENST00000560361ZHX3chr2039813841-113275715725236

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000217131ENST00000309060CTSZchr2057571694-ZHX3chr2039813841-0.0030017740.9969982
ENST00000217131ENST00000558993CTSZchr2057571694-ZHX3chr2039813841-0.0194826310.9805173
ENST00000217131ENST00000544979CTSZchr2057571694-ZHX3chr2039813841-0.0201056150.97989434
ENST00000217131ENST00000432768CTSZchr2057571694-ZHX3chr2039813841-0.0262372340.97376275
ENST00000217131ENST00000540170CTSZchr2057572658-ZHX3chr2039813841-0.0046232010.9953768
ENST00000217131ENST00000559234CTSZchr2057572658-ZHX3chr2039813841-0.0037898050.9962102
ENST00000217131ENST00000557816CTSZchr2057572658-ZHX3chr2039813841-0.0136428720.9863571
ENST00000217131ENST00000560361CTSZchr2057572658-ZHX3chr2039813841-0.013808390.98619163

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Fusion Genomic Features for CTSZ-ZHX3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CTSZ-ZHX3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr20:57571694/chr20:39813841)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneZHX3chr20:57571694chr20:39813841ENST0000030906035304_363953957.0DNA bindingHomeobox 1
TgeneZHX3chr20:57571694chr20:39813841ENST0000030906035494_553953957.0DNA bindingHomeobox 2
TgeneZHX3chr20:57571694chr20:39813841ENST0000030906035612_671953957.0DNA bindingHomeobox 3
TgeneZHX3chr20:57571694chr20:39813841ENST0000030906035764_823953957.0DNA bindingHomeobox 4
TgeneZHX3chr20:57571694chr20:39813841ENST0000030906035835_894953957.0DNA bindingHomeobox 5
TgeneZHX3chr20:57571694chr20:39813841ENST0000043276824304_363953957.0DNA bindingHomeobox 1
TgeneZHX3chr20:57571694chr20:39813841ENST0000043276824494_553953957.0DNA bindingHomeobox 2
TgeneZHX3chr20:57571694chr20:39813841ENST0000043276824612_671953957.0DNA bindingHomeobox 3
TgeneZHX3chr20:57571694chr20:39813841ENST0000043276824764_823953957.0DNA bindingHomeobox 4
TgeneZHX3chr20:57571694chr20:39813841ENST0000043276824835_894953957.0DNA bindingHomeobox 5
TgeneZHX3chr20:57571694chr20:39813841ENST0000054017025304_3639532914.3333333333335DNA bindingHomeobox 1
TgeneZHX3chr20:57571694chr20:39813841ENST0000054017025494_5539532914.3333333333335DNA bindingHomeobox 2
TgeneZHX3chr20:57571694chr20:39813841ENST0000054017025612_6719532914.3333333333335DNA bindingHomeobox 3
TgeneZHX3chr20:57571694chr20:39813841ENST0000054017025764_8239532914.3333333333335DNA bindingHomeobox 4
TgeneZHX3chr20:57571694chr20:39813841ENST0000054017025835_8949532914.3333333333335DNA bindingHomeobox 5
TgeneZHX3chr20:57571694chr20:39813841ENST0000055923424304_363953957.0DNA bindingHomeobox 1
TgeneZHX3chr20:57571694chr20:39813841ENST0000055923424494_553953957.0DNA bindingHomeobox 2
TgeneZHX3chr20:57571694chr20:39813841ENST0000055923424612_671953957.0DNA bindingHomeobox 3
TgeneZHX3chr20:57571694chr20:39813841ENST0000055923424764_823953957.0DNA bindingHomeobox 4
TgeneZHX3chr20:57571694chr20:39813841ENST0000055923424835_894953957.0DNA bindingHomeobox 5
TgeneZHX3chr20:57571694chr20:39813841ENST0000056036168304_363953957.0DNA bindingHomeobox 1
TgeneZHX3chr20:57571694chr20:39813841ENST0000056036168494_553953957.0DNA bindingHomeobox 2
TgeneZHX3chr20:57571694chr20:39813841ENST0000056036168612_671953957.0DNA bindingHomeobox 3
TgeneZHX3chr20:57571694chr20:39813841ENST0000056036168764_823953957.0DNA bindingHomeobox 4
TgeneZHX3chr20:57571694chr20:39813841ENST0000056036168835_894953957.0DNA bindingHomeobox 5
TgeneZHX3chr20:57572658chr20:39813841ENST0000030906035304_363953957.0DNA bindingHomeobox 1
TgeneZHX3chr20:57572658chr20:39813841ENST0000030906035494_553953957.0DNA bindingHomeobox 2
TgeneZHX3chr20:57572658chr20:39813841ENST0000030906035612_671953957.0DNA bindingHomeobox 3
TgeneZHX3chr20:57572658chr20:39813841ENST0000030906035764_823953957.0DNA bindingHomeobox 4
TgeneZHX3chr20:57572658chr20:39813841ENST0000030906035835_894953957.0DNA bindingHomeobox 5
TgeneZHX3chr20:57572658chr20:39813841ENST0000043276824304_363953957.0DNA bindingHomeobox 1
TgeneZHX3chr20:57572658chr20:39813841ENST0000043276824494_553953957.0DNA bindingHomeobox 2
TgeneZHX3chr20:57572658chr20:39813841ENST0000043276824612_671953957.0DNA bindingHomeobox 3
TgeneZHX3chr20:57572658chr20:39813841ENST0000043276824764_823953957.0DNA bindingHomeobox 4
TgeneZHX3chr20:57572658chr20:39813841ENST0000043276824835_894953957.0DNA bindingHomeobox 5
TgeneZHX3chr20:57572658chr20:39813841ENST0000054017025304_3639532914.3333333333335DNA bindingHomeobox 1
TgeneZHX3chr20:57572658chr20:39813841ENST0000054017025494_5539532914.3333333333335DNA bindingHomeobox 2
TgeneZHX3chr20:57572658chr20:39813841ENST0000054017025612_6719532914.3333333333335DNA bindingHomeobox 3
TgeneZHX3chr20:57572658chr20:39813841ENST0000054017025764_8239532914.3333333333335DNA bindingHomeobox 4
TgeneZHX3chr20:57572658chr20:39813841ENST0000054017025835_8949532914.3333333333335DNA bindingHomeobox 5
TgeneZHX3chr20:57572658chr20:39813841ENST0000055923424304_363953957.0DNA bindingHomeobox 1
TgeneZHX3chr20:57572658chr20:39813841ENST0000055923424494_553953957.0DNA bindingHomeobox 2
TgeneZHX3chr20:57572658chr20:39813841ENST0000055923424612_671953957.0DNA bindingHomeobox 3
TgeneZHX3chr20:57572658chr20:39813841ENST0000055923424764_823953957.0DNA bindingHomeobox 4
TgeneZHX3chr20:57572658chr20:39813841ENST0000055923424835_894953957.0DNA bindingHomeobox 5
TgeneZHX3chr20:57572658chr20:39813841ENST0000056036168304_363953957.0DNA bindingHomeobox 1
TgeneZHX3chr20:57572658chr20:39813841ENST0000056036168494_553953957.0DNA bindingHomeobox 2
TgeneZHX3chr20:57572658chr20:39813841ENST0000056036168612_671953957.0DNA bindingHomeobox 3
TgeneZHX3chr20:57572658chr20:39813841ENST0000056036168764_823953957.0DNA bindingHomeobox 4
TgeneZHX3chr20:57572658chr20:39813841ENST0000056036168835_894953957.0DNA bindingHomeobox 5
TgeneZHX3chr20:57571694chr20:39813841ENST00000309060351_107953957.0RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST0000030906035303_502953957.0RegionNote=Required for repressor activity
TgeneZHX3chr20:57571694chr20:39813841ENST0000030906035497_555953957.0RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST00000432768241_107953957.0RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST0000043276824303_502953957.0RegionNote=Required for repressor activity
TgeneZHX3chr20:57571694chr20:39813841ENST0000043276824497_555953957.0RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST00000540170251_1079532914.3333333333335RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST0000054017025303_5029532914.3333333333335RegionNote=Required for repressor activity
TgeneZHX3chr20:57571694chr20:39813841ENST0000054017025497_5559532914.3333333333335RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST00000559234241_107953957.0RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST0000055923424303_502953957.0RegionNote=Required for repressor activity
TgeneZHX3chr20:57571694chr20:39813841ENST0000055923424497_555953957.0RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST00000560361681_107953957.0RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST0000056036168303_502953957.0RegionNote=Required for repressor activity
TgeneZHX3chr20:57571694chr20:39813841ENST0000056036168497_555953957.0RegionNote=Required for nuclear localization
TgeneZHX3chr20:57572658chr20:39813841ENST00000309060351_107953957.0RegionNote=Required for nuclear localization
TgeneZHX3chr20:57572658chr20:39813841ENST0000030906035303_502953957.0RegionNote=Required for repressor activity
TgeneZHX3chr20:57572658chr20:39813841ENST0000030906035497_555953957.0RegionNote=Required for nuclear localization
TgeneZHX3chr20:57572658chr20:39813841ENST00000432768241_107953957.0RegionNote=Required for nuclear localization
TgeneZHX3chr20:57572658chr20:39813841ENST0000043276824303_502953957.0RegionNote=Required for repressor activity
TgeneZHX3chr20:57572658chr20:39813841ENST0000043276824497_555953957.0RegionNote=Required for nuclear localization
TgeneZHX3chr20:57572658chr20:39813841ENST00000540170251_1079532914.3333333333335RegionNote=Required for nuclear localization
TgeneZHX3chr20:57572658chr20:39813841ENST0000054017025303_5029532914.3333333333335RegionNote=Required for repressor activity
TgeneZHX3chr20:57572658chr20:39813841ENST0000054017025497_5559532914.3333333333335RegionNote=Required for nuclear localization
TgeneZHX3chr20:57572658chr20:39813841ENST00000559234241_107953957.0RegionNote=Required for nuclear localization
TgeneZHX3chr20:57572658chr20:39813841ENST0000055923424303_502953957.0RegionNote=Required for repressor activity
TgeneZHX3chr20:57572658chr20:39813841ENST0000055923424497_555953957.0RegionNote=Required for nuclear localization
TgeneZHX3chr20:57572658chr20:39813841ENST00000560361681_107953957.0RegionNote=Required for nuclear localization
TgeneZHX3chr20:57572658chr20:39813841ENST0000056036168303_502953957.0RegionNote=Required for repressor activity
TgeneZHX3chr20:57572658chr20:39813841ENST0000056036168497_555953957.0RegionNote=Required for nuclear localization
TgeneZHX3chr20:57571694chr20:39813841ENST0000030906035109_132953957.0Zinc fingerNote=C2H2-type 2
TgeneZHX3chr20:57571694chr20:39813841ENST000003090603577_100953957.0Zinc fingerNote=C2H2-type 1
TgeneZHX3chr20:57571694chr20:39813841ENST0000043276824109_132953957.0Zinc fingerNote=C2H2-type 2
TgeneZHX3chr20:57571694chr20:39813841ENST000004327682477_100953957.0Zinc fingerNote=C2H2-type 1
TgeneZHX3chr20:57571694chr20:39813841ENST0000054017025109_1329532914.3333333333335Zinc fingerNote=C2H2-type 2
TgeneZHX3chr20:57571694chr20:39813841ENST000005401702577_1009532914.3333333333335Zinc fingerNote=C2H2-type 1
TgeneZHX3chr20:57571694chr20:39813841ENST0000055923424109_132953957.0Zinc fingerNote=C2H2-type 2
TgeneZHX3chr20:57571694chr20:39813841ENST000005592342477_100953957.0Zinc fingerNote=C2H2-type 1
TgeneZHX3chr20:57571694chr20:39813841ENST0000056036168109_132953957.0Zinc fingerNote=C2H2-type 2
TgeneZHX3chr20:57571694chr20:39813841ENST000005603616877_100953957.0Zinc fingerNote=C2H2-type 1
TgeneZHX3chr20:57572658chr20:39813841ENST0000030906035109_132953957.0Zinc fingerNote=C2H2-type 2
TgeneZHX3chr20:57572658chr20:39813841ENST000003090603577_100953957.0Zinc fingerNote=C2H2-type 1
TgeneZHX3chr20:57572658chr20:39813841ENST0000043276824109_132953957.0Zinc fingerNote=C2H2-type 2
TgeneZHX3chr20:57572658chr20:39813841ENST000004327682477_100953957.0Zinc fingerNote=C2H2-type 1
TgeneZHX3chr20:57572658chr20:39813841ENST0000054017025109_1329532914.3333333333335Zinc fingerNote=C2H2-type 2
TgeneZHX3chr20:57572658chr20:39813841ENST000005401702577_1009532914.3333333333335Zinc fingerNote=C2H2-type 1
TgeneZHX3chr20:57572658chr20:39813841ENST0000055923424109_132953957.0Zinc fingerNote=C2H2-type 2
TgeneZHX3chr20:57572658chr20:39813841ENST000005592342477_100953957.0Zinc fingerNote=C2H2-type 1
TgeneZHX3chr20:57572658chr20:39813841ENST0000056036168109_132953957.0Zinc fingerNote=C2H2-type 2
TgeneZHX3chr20:57572658chr20:39813841ENST000005603616877_100953957.0Zinc fingerNote=C2H2-type 1


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Fusion Gene Sequence for CTSZ-ZHX3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>20548_20548_1_CTSZ-ZHX3_CTSZ_chr20_57571694_ENST00000217131_ZHX3_chr20_39813841_ENST00000309060_length(transcript)=7674nt_BP=920nt
GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCG
GAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGCTTCTGCTGCTCGTGCTGCTGGCGGGCGCGG
CGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACC
CCCGGCCTCATGAGTACCTGTCCCCAGCGGATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCC
GGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG
GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGT
GGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGGACCAGGAGTGTGACAAGTTTAACCAATGTG
GGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGA
AGATGATGGCAGAAATCTATGCAAATGGTCCCATCAGCTGTGGAATAATGGCAACAGAAAGACTGGCTAACTACACCGGAGGCATCTATG
CCGAATACCAGGACACCACATATATAAACCATGTCGTTTCTGTGGCTGGGTGGGGCATCAGTGATGGGACTGAGTACTGGATTGTCCGGA
ATTCATGGGGTGAACCATGGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAACCGCCTGCCACGTGGAAG
AGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGGGAGAGCTTCCAGAATCCTCGCAGACAGCCC
AGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTTCCTCCCACAATGTAGGA
CCTTTCCTTTACCTTCCAATGGATAAAATAGTTCAGAGTTCATAGTCATATTCATAGACACAGAATCAAGCTTTTAACATATACATCCAC
CTCTATATGTTAAATAAAACATCAGATTATCAACACTGTCATTACGTAGAAACTTTGGTTAGCCAAGCAGTGCATTGTCAGTTACGTCAT
CTCTAAAAATGACCTGTGTCTGTTCTCTGGGGATTGCTGGGTCACAGGTGCCCCTCACCTTCCACAGTCAGGCAGGGAAGTTATAGGCAC
AAAGCTACGTCTGGAACCCCTTTGTGCCCCCTTTGTGTTCCTCAAGGAAGCAGTACCTTTGAAGAGATCTCTGCTGCATTAAGTGATGAC
CGGCTACGTTTCATGTCAGGCTTGCTTTGCCTTGTGGGCTACTCAGTGCAGAACCTGCTGTAACCCTCAGTTCAAAAAATGGACTGGCAA
TGTGATTAGCGTTGGATGCTTTACCATTCTCTTTAGTTGTTACCGTAATTCTGCTTTTTCATGGGAGTTTGAATCATGGACCATAACTTT
TCAGTTATCAGATCAACTAAAGAAACATTTGTTGTTAAGCCTAATGTGCTGACCTATGTGCCTGCATTTTTTTTTTAATCTAGACATGTT
TGGAGTGAGAGAAAGATGGAAAAAAGACATGGGGTAGGGACGTAAGTGGAAATCTATAGCCACAGCCTGAAGCTTTGACCACTGCGGTTT
TCAGAGCCCTTTCTCCACACTCATTTCAGAGCCTCCTATGGTTTGGGAAGGAATAACACACTGGCCCATTAGTAAGGGTGAAGGCTGGAG
GGATTTGTTGACTTCTTGGAATTATCAGAGGTAGGGTGGTCTTTAGCACAAAGACTTGCATGCAGAGATCCCTGGCAGAACACCCAGAGT
GCCCGTGGCTCCCACCCCAGGGTCTGGCCGGTGTGCTGGATGCATGCCCAAGGGTGCTGGGCATCACTGGTCCTTGTGAGGATGCTTTTA
AAGTTTTATATTTATGTCCCCAAACTTGGAAACAAGAACTCTACTTTAGCCTAACCCTCATGTCCTTTTTTGAATTGAGAAAATTACAGG
AAATGGTGCCTTTGAAAATTAGAAAACTTGCTTACAGAGCTGTTCTAAATGGTAAATCCTCAATTTCCCCAAGACCGGTTGCTCTGAGAG
TAGCTGGTAAAGAGGGGCGAACTAAAGACCTGTCCACCTGTAGCTCCGCTCATTTCTTAGAAACCACCTGCTTCCCAGAGTGCCAAGCCA
CAAGTACCAGGCTTCGTGGGCACAGACACCTCCTGGGCTGGGCAGAGTGACAGTGCTAGAAGACCCCAGAGAGAGGGCAAGGGCTTTGGG
CAAGAAGCACTGGTGGTGTTTTAGGGACCGTCCTTCTCCCCTACCCAGGGAACTGGACCTGGCAGGGCACCGTGCTCATGTGGCTCCAAG
GACAAGCATGGCGGTGGCCCCTTCTGCCTTCCAGGAGAGGTCTTGCTTTTGAAACCAAAATCATGTTCTTCTAAAGTGTCATCTTCTGCC
CTCCCTGTCCCAATAGGGACCACATCTTATTTGTCTCAAACAGGGACTTGTGAGTACTTGGCAAGTTTTGCAGCCTATTTTTGTATTCTT
AATTTGGGGAGTAAAGATGTTTGGTCTCAAAAACCTTTGAGGAATTGCCAAGAATGGCGAGTGATTGCTTTCCTTCAGAGAACAGACACT
TGGAATTTCTCCTTTTAGTGTTTATATACGTGCAGATTAATTTATATATATATATATACACACACACATATACAGTATAAATACTCATTT
GATTCTCGTAAAACGCGCATCTGGCGTGTGCAGTTGAGAAACTTGGTGGCACATGGGTGTTGGGGGAGTAGCCTGTGTTGGAGGGACACC
AGTGCACTAGGCAGCTGGGGCGGCCCAGGCTGAAGCCATCTCCGGGTGTCTGAGAAACCACCCAGTGCCTCACCTCCAGATCCTGCTGGC
ATCACCTCCAGAGCCCTGCATGCACTGGCTGAAGAGTTGGTCTGTGGAGAGGATTTTCTTGGTTACTTGTATTCACGGTTAATTTACAAC
CCAAACAGCAAAACACAGTTGGTGGACAAGTTCATGCAGGACCTACAGTGACCCAGCCATGGGCACTAGCTCATCTTTCAGGTGGAAAAG
TACAGTGCTGCCTGCCCTGGTATGTTTTTCTTATAGATGTTAGCCCTGCCCAACAGCCAGGGCTACACTACAAAAGGCAAGAATGCCCAT
GTAAGGAGCCCAGCAGTCTGGACAGATCCTTCTTCCTCTGCTGTTGGATGAGAGTGAGTGAGTATGCTCTGGACCTTATCCTTGAAAGAT
GATCAAAAGCGATGATGAGGGAGGCAGTCATCACGCAGGTGCTTAAAGGGACATTGTAGGAGGTACTCAAGGGTTTGGGGGCAAAACCCT
GAATCCAGCCAGTCGTGCACAGAGACACACCCACACTAGCCCAGTGGCAGTGGGGGATGTGGGATGGCAGCAGCCAGGTATGTAGCCCTG
TCACAGGACAGCTCACTGTGGTTTTGCACACTGCCTAAGGGTTAAATTGTGTTGTTGCCTTCAGTAGAAGGCATTTGTGGGCTGCAGAGT
TGAGAGTTGGGTGAGGTTAGTCTCTCCTGAAGAAAAAGCCTATAAAAAGTGGCTAATCTTATCCCTTTTCTCTGTATGCAGTTGGACTCG
TCAGAGATAGTAAAATCATCTTTTAGTGTTTTTTTGTTGCTGATGTCTTGTACCCATTTGTTTTTTACATGGGGTTGTAGATCGAGTTCT
CAAAGGTGAAACCAGATGATCATTCTGATAAAGGAAATTTAAATTTGATACATATGCTTTGTATATTTTGATTACTTGTTTTCGTTTTTG
ACTATAAAGGAGCTTTTTTATTTTGGGAGGGGAGGAGTGTCATTTTTGAGAATCTTGGGTTCCTGAAAAAGAACGCCCTAGTTGGATGGC
TTGCCAGGGCCTTGGGGTTTGGTAGTGATTGTACAACTTAAAGCTCCTTTCTCTTGGCTGAGTGACAGGTGGCTGTTCAGGTGGACCAAA
GCACCTTGACACAAGGACTCCACACTGTGCTCTCTAGTAGCACAAGGAGGAAGTTGGACAGAACATTGGGTAGTGCCTTGCGGGCTCACA
CATGTACTAGTGGTCTCATCTCCAGCTAGCCTTGGGAGGCCGTCCCACCAGGAAATCTCTCTATTCCGTAGCCTGAGATGTGCCCTTGTG
GGTTTTATCCTGCTCAGTCAGTGGCCTAGGGGCAGGTCCTGTGTTCTCTCCCTCTCTCTCCTGGCTCTGGGACATCTGTCCCTGGCTGCC
TTTCATGGAGGAAGGACACTGGCCTTTCTGGTTGGATGCTGTGTGGATGCTCTCTGCTTGAGCCTCGTGGTCTCTTGTCTCTTTTTGGAC
CAATATCCTCAGATTGGTGCAGCTTTTTCAGTTCAGATATCACACCCCAAGTGGATAAAGGCAACTTGCAGGAGAGGAGAGCCAGCCAAG
AAGAAAATTTTAAAACCAAACCTCGTTTAGGATTTTCCTAAAGTCATCTTCTCTTTTTTCTTGCTCAGAGTTTACCTGGGAGATTTCACC
AGTTTGACTCACCATTTGCAGATGTGCTTTTGTATTAAATTTAAATTTTCACATATCACATCCATTCTCAAGGTAGTTATATGCTGGAGA
AGAAAAATCCTCTAGACACATGAAGGCCCACATAGTCAAGTCTTCCAGGGCAAAGCCAGCAGCCCACCCAGGTCAGGTAGCCAGCAGGGC
TCAGTTCCCCTCACTCCAGACACGGACCCTCCTCTTCAGGGTCTCTTGACCCAGCTTCCTTCTCTCCTTTTACCTGAGAGCACAGACCTC
TCTCAGCCAGCCTGCCCAGACCACGGGGGGCTACTCCCATGTAGTTTGGGGAGCACTTGATCTCAGAAAAGCTCCATTGTCTGAGCAAAT
GGGCAGTTGTGGAGCTCAAGCCTTTCTCCTGTGCTCAAGTCCCTTCCCCAAGCAAGGCTTCAACCTCATCTACCCACCATGTAGTTTTCT
CTGGCCATTTAAGTGGGGCGGCAGGGACATGGTTGGGCCATGCCACACCAGGGCTGGTGAGGCAACCAGTTTTGATTTTGACAGAGTGGC
TGGAGGAAAAGTGGCAATCAAGGTGCTGCTTGGTTTGCTCTGAGTGCAAATGGAACCAACAGGTTTCTGCTGCAATCTGTGTGTTCCCAG
TGCCAGGTCACACCAGGAGGGGTGGGGCAGGGCTAACCAAGTGGTCTCTGAACTCACCGAGCGTCTGCACTTGGTTGTGAAGTTAATGGG
AGTACAGAGAGCGTCTGGCCTTGGAGAGGGGTTGAGAGCCTCCTTTTTGGTTCTTCATTCCTGAGCTCTTGCCTGCCCACAAATCTGACC
TCTTTGAATGGGGACGCAGTCCTTCAACAGAGAAGTTTCTATGGCAAAGAAGTTTCTATTTAGCTCTAGATCCAGCAGAGTCATCCATTC
TAACTGCCCTGAAGTCTAGAGCAGGGGAGGGAACCCAGAGGCTGGGGATGAGACTAGGCAGACCCTGGTTACCATATGGACAAGGACAGG
GGAAAGCACCCCCTTCCTCAATTTCTGAAAGTTCTATCTTTGGGTTCGCAGGACTTTGAGGATGATAAAGAACATATAGGTACTAGCTTG
TTGTTGCTGGTCCAAAGCTTCCACAGCCCTGAGAATTTGGCTTTCGTGGCTGCTCTGGCAGCTGAGCGAAGGGAGGAAGGCAGCCGCTCT
GGTGGGGACTCTAGGCACCTTCCCTGCTGTCCACTTGGATAGGCGGTGAGCCCCAGGGTACTGAGAGGAGCCTGAGCATTTACCTGCCAT
TAGTGCCTCTTCCTTCAGGAGACTGGCTTGAAACGTGTGTTCATGTGCGCGTGCACACACACACATGAGCACCTGTATGTGTTAATGAAT
AGTTTTTCTTGGTTAATGCTTTTTAACTTCTGTTCCTTTCCGTAAGTGGATGATTCAAAATTAACGTGACTTGGCTGGGCGCAGTGGCTC
ACACCTGTAATCCCAGCACTTTGGGAGGCCAAGGGAGGCGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGATCGGCATGGTGAAAC
CCCGTTTCTACTAAAAATACAAAAATTAGCCGGGCGTGGTGGTGCGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGAAGGAGAATCA
CTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCTGAGATCGTGCCACTGCACTCCAGCCTGGGCGACAGAGCGAAACTCCGTCTCAAAAAA
AAAAAAAAAACTTAATGTGACTGGAGTTAAAAGTGAAATGTCAGGTTGTTTAGTCACTGAATAGAGAGCTACAAGTGCTTGGTCTTTCCC
AAGAATCAAACCTGAGTAGAAATACATTTAAAAGAAAAATCTACATGGTACCTATGAATCCTGTAATTTGTTTAGGGAGATCTTGTCACT
CATCCCTGGTTCCTGCCCATACTGTTTGGTCTCGTTCTTGCAGTTTGCTTGGAACAGGGCCAGAGCCCCACATGAGATTGTCAGCAGGAG
TGAGGAGCGCCAGTCCCTACTCCTCAGCAGGGACCCAGCACAGCAATCCGGTTGTTCTCGGTTAGACTGGGTCGGGGCCAGGGGAGAAGC
AGTCACCCCTGTGTAGAGGGTTCCCGCTGTGCTTCTGAGCAGTTGCTTTGTTCAGAAGTGTTAGGAGGGTCAGATTGTGCCATAATTGTT
ATTAAAGAGAAAACACGCCCACCTTCCTTTCTCCCCTGCTGGCCATTGTTCATTGAGTTTTACTGAGGGCAGCCTTTGTGGAAGTCAGGG
AGGTTGCCAAAGGCCTGTAGATGCCTCCTGACAAGGTCTTGATTCCTGGTTTTCTAGCACCCATTTGCATTTTGGTCTTCAGCACAAAGC
CTTGTTCCCTGTGGCCGGACTTCTGGGCAATAAGACTGGGGAGTGACTGTTGAGCAGTCTGCTGTCAGGAGAGATGGCTGAAAAGGTGAT
CATCTTGGTGCTAAACAAGTAAGAGGCAACTGCCCTGTTTTTGTTTGTTTTGAGGCACAATGAAACTTTAGCCAAACTCTGCAAGAGGGT
CCCATCTCCTGCCATGGCCAGGTGTGAGAGACCAAACCGAGAAAACAGCATACTCTATCACTTAAGCCTTGGGTAGAATGGGAATTCTTT
ACCCTGGGTAAACGTTTTAACAAAAAAATGGAACTTAACTTCGGTTTGGACTGTGGTCGTGCTGAGGCAGGAGTGGGGTTGCCCTCTTGG
GGCTGAATCTCCAGGCCTCACGAGGTCCCCTGTGGGGATGCTGCTATTTCTAAGATGCAAATTGCACATTTCCTAGATTTTGTATCTGTG
GATTTGGATAAGGGAGGGGAACACGGACAAATTGCTTGTACAATTTGAAATGGGCCTCAATGGTACTTCAAACCTTTTGATTATTCCTAA

>20548_20548_1_CTSZ-ZHX3_CTSZ_chr20_57571694_ENST00000217131_ZHX3_chr20_39813841_ENST00000309060_length(amino acids)=375AA_BP=284
MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDG
VNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQE
CDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDG
TEYWIVRNSWGEPWKQTEFDLINVKDWPVWETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQ

--------------------------------------------------------------
>20548_20548_2_CTSZ-ZHX3_CTSZ_chr20_57571694_ENST00000217131_ZHX3_chr20_39813841_ENST00000432768_length(transcript)=1206nt_BP=920nt
GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCG
GAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGCTTCTGCTGCTCGTGCTGCTGGCGGGCGCGG
CGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACC
CCCGGCCTCATGAGTACCTGTCCCCAGCGGATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCC
GGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG
GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGT
GGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGGACCAGGAGTGTGACAAGTTTAACCAATGTG
GGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGA
AGATGATGGCAGAAATCTATGCAAATGGTCCCATCAGCTGTGGAATAATGGCAACAGAAAGACTGGCTAACTACACCGGAGGCATCTATG
CCGAATACCAGGACACCACATATATAAACCATGTCGTTTCTGTGGCTGGGTGGGGCATCAGTGATGGGACTGAGTACTGGATTGTCCGGA
ATTCATGGGGTGAACCATGGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAACCGCCTGCCACGTGGAAG
AGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGGGAGAGCTTCCAGAATCCTCGCAGACAGCCC
AGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTTCCTCCCACAATGTAGGA

>20548_20548_2_CTSZ-ZHX3_CTSZ_chr20_57571694_ENST00000217131_ZHX3_chr20_39813841_ENST00000432768_length(amino acids)=375AA_BP=284
MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDG
VNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQE
CDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDG
TEYWIVRNSWGEPWKQTEFDLINVKDWPVWETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQ

--------------------------------------------------------------
>20548_20548_3_CTSZ-ZHX3_CTSZ_chr20_57571694_ENST00000217131_ZHX3_chr20_39813841_ENST00000544979_length(transcript)=1295nt_BP=920nt
GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCG
GAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGCTTCTGCTGCTCGTGCTGCTGGCGGGCGCGG
CGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACC
CCCGGCCTCATGAGTACCTGTCCCCAGCGGATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCC
GGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG
GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGT
GGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGGACCAGGAGTGTGACAAGTTTAACCAATGTG
GGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGA
AGATGATGGCAGAAATCTATGCAAATGGTCCCATCAGCTGTGGAATAATGGCAACAGAAAGACTGGCTAACTACACCGGAGGCATCTATG
CCGAATACCAGGACACCACATATATAAACCATGTCGTTTCTGTGGCTGGGTGGGGCATCAGTGATGGGACTGAGTACTGGATTGTCCGGA
ATTCATGGGGTGAACCATGGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAACCGCCTGCCACGTGGAAG
AGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGGGAGAGCTTCCAGAATCCTCGCAGACAGCCC
AGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTTCCTCCCACAATGTAGGA
CCTTTCCTTTACCTTCCAATGGATAAAATAGTTCAGAGTTCATAGTCATATTCATAGACACAGAATCAAGCTTTTAACATATACATCCAC

>20548_20548_3_CTSZ-ZHX3_CTSZ_chr20_57571694_ENST00000217131_ZHX3_chr20_39813841_ENST00000544979_length(amino acids)=375AA_BP=284
MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDG
VNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQE
CDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDG
TEYWIVRNSWGEPWKQTEFDLINVKDWPVWETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQ

--------------------------------------------------------------
>20548_20548_4_CTSZ-ZHX3_CTSZ_chr20_57571694_ENST00000217131_ZHX3_chr20_39813841_ENST00000558993_length(transcript)=1301nt_BP=920nt
GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCG
GAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGCTTCTGCTGCTCGTGCTGCTGGCGGGCGCGG
CGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACC
CCCGGCCTCATGAGTACCTGTCCCCAGCGGATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCC
GGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG
GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGT
GGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGGACCAGGAGTGTGACAAGTTTAACCAATGTG
GGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGA
AGATGATGGCAGAAATCTATGCAAATGGTCCCATCAGCTGTGGAATAATGGCAACAGAAAGACTGGCTAACTACACCGGAGGCATCTATG
CCGAATACCAGGACACCACATATATAAACCATGTCGTTTCTGTGGCTGGGTGGGGCATCAGTGATGGGACTGAGTACTGGATTGTCCGGA
ATTCATGGGGTGAACCATGGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAACCGCCTGCCACGTGGAAG
AGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGGGAGAGCTTCCAGAATCCTCGCAGACAGCCC
AGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTTCCTCCCACAATGTAGGA
CCTTTCCTTTACCTTCCAATGGATAAAATAGTTCAGAGTTCATAGTCATATTCATAGACACAGAATCAAGCTTTTAACATATACATCCAC

>20548_20548_4_CTSZ-ZHX3_CTSZ_chr20_57571694_ENST00000217131_ZHX3_chr20_39813841_ENST00000558993_length(amino acids)=375AA_BP=284
MGLGAGSGAGPRSRRGAMARRGPGWRPLLLLVLLAGAAQGGLYFRRGQTCYRPLRGDGLAPLGRSTYPRPHEYLSPADLPKSWDWRNVDG
VNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSVQNVIDCGNAGSCEGGNDLSVWDYAHQHGIPDETCNNYQAKDQE
CDKFNQCGTCNEFKECHAIRNYTLWRVGDYGSLSGREKMMAEIYANGPISCGIMATERLANYTGGIYAEYQDTTYINHVVSVAGWGISDG
TEYWIVRNSWGEPWKQTEFDLINVKDWPVWETACHVEEPNPTLCCHMPFPCPAAGHLGELPESSQTAQSLPLPSACPPPSKQQARWGSHQ

--------------------------------------------------------------
>20548_20548_5_CTSZ-ZHX3_CTSZ_chr20_57572658_ENST00000217131_ZHX3_chr20_39813841_ENST00000540170_length(transcript)=6839nt_BP=757nt
GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCG
GAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGCTTCTGCTGCTCGTGCTGCTGGCGGGCGCGG
CGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACC
CCCGGCCTCATGAGTACCTGTCCCCAGCGGATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCC
GGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG
GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGT
GGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGGACCAGGAGTGTGACAAGTTTAACCAATGTG
GGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGA
AGATGATGGCAGAAATCTATGCAAATGGTCCCATCAGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAAC
CGCCTGCCACGTGGAAGAGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGGGAGAGCTTCCAGA
ATCCTCGCAGACAGCCCAGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTT
CCTCCCACAATGTAGGACCTTTCCTTTACCTTCCAATGGATAAAATAGTTCAGAGTTCATAGTCATATTCATAGACACAGAATCAAGCTT
TTAACATATACATCCACCTCTATATGTTAAATAAAACATCAGATTATCAACACTGTCATTACGTAGAAACTTTGGTTAGCCAAGCAGTGC
ATTGTCAGTTACGTCATCTCTAAAAATGACCTGTGTCTGTTCTCTGGGGATTGCTGGGTCACAGGTGCCCCTCACCTTCCACAGTCAGGC
AGGGAAGTTATAGGCACAAAGCTACGTCTGGAACCCCTTTGTGCCCCCTTTGTGTTCCTCAAGGAAGCAGTACCTTTGAAGAGATCTCTG
CTGCATTAAGTGATGACCGGCTACGTTTCATGTCAGGCTTGCTTTGCCTTGTGGGCTACTCAGTGCAGAACCTGCTGTAACCCTCAGTTC
AAAAAATGGACTGGCAATGTGATTAGCGTTGGATGCTTTACCATTCTCTTTAGTTGTTACCGTAATTCTGCTTTTTCATGGGAGTTTGAA
TCATGGACCATAACTTTTCAGTTATCAGATCAACTAAAGAAACATTTGTTGTTAAGCCTAATGTGCTGACCTATGTGCCTGCATTTTTTT
TTTAATCTAGACATGTTTGGAGTGAGAGAAAGATGGAAAAAAGACATGGGGTAGGGACGTAAGTGGAAATCTATAGCCACAGCCTGAAGC
TTTGACCACTGCGGTTTTCAGAGCCCTTTCTCCACACTCATTTCAGAGCCTCCTATGGTTTGGGAAGGAATAACACACTGGCCCATTAGT
AAGGGTGAAGGCTGGAGGGATTTGTTGACTTCTTGGAATTATCAGAGGTAGGGTGGTCTTTAGCACAAAGACTTGCATGCAGAGATCCCT
GGCAGAACACCCAGAGTGCCCGTGGCTCCCACCCCAGGGTCTGGCCGGTGTGCTGGATGCATGCCCAAGGGTGCTGGGCATCACTGGTCC
TTGTGAGGATGCTTTTAAAGTTTTATATTTATGTCCCCAAACTTGGAAACAAGAACTCTACTTTAGCCTAACCCTCATGTCCTTTTTTGA
ATTGAGAAAATTACAGGAAATGGTGCCTTTGAAAATTAGAAAACTTGCTTACAGAGCTGTTCTAAATGGTAAATCCTCAATTTCCCCAAG
ACCGGTTGCTCTGAGAGTAGCTGGTAAAGAGGGGCGAACTAAAGACCTGTCCACCTGTAGCTCCGCTCATTTCTTAGAAACCACCTGCTT
CCCAGAGTGCCAAGCCACAAGTACCAGGCTTCGTGGGCACAGACACCTCCTGGGCTGGGCAGAGTGACAGTGCTAGAAGACCCCAGAGAG
AGGGCAAGGGCTTTGGGCAAGAAGCACTGGTGGTGTTTTAGGGACCGTCCTTCTCCCCTACCCAGGGAACTGGACCTGGCAGGGCACCGT
GCTCATGTGGCTCCAAGGACAAGCATGGCGGTGGCCCCTTCTGCCTTCCAGGAGAGGTCTTGCTTTTGAAACCAAAATCATGTTCTTCTA
AAGTGTCATCTTCTGCCCTCCCTGTCCCAATAGGGACCACATCTTATTTGTCTCAAACAGGGACTTGTGAGTACTTGGCAAGTTTTGCAG
CCTATTTTTGTATTCTTAATTTGGGGAGTAAAGATGTTTGGTCTCAAAAACCTTTGAGGAATTGCCAAGAATGGCGAGTGATTGCTTTCC
TTCAGAGAACAGACACTTGGAATTTCTCCTTTTAGTGTTTATATACGTGCAGATTAATTTATATATATATATATACACACACACATATAC
AGTATAAATACTCATTTGATTCTCGTAAAACGCGCATCTGGCGTGTGCAGTTGAGAAACTTGGTGGCACATGGGTGTTGGGGGAGTAGCC
TGTGTTGGAGGGACACCAGTGCACTAGGCAGCTGGGGCGGCCCAGGCTGAAGCCATCTCCGGGTGTCTGAGAAACCACCCAGTGCCTCAC
CTCCAGATCCTGCTGGCATCACCTCCAGAGCCCTGCATGCACTGGCTGAAGAGTTGGTCTGTGGAGAGGATTTTCTTGGTTACTTGTATT
CACGGTTAATTTACAACCCAAACAGCAAAACACAGTTGGTGGACAAGTTCATGCAGGACCTACAGTGACCCAGCCATGGGCACTAGCTCA
TCTTTCAGGTGGAAAAGTACAGTGCTGCCTGCCCTGGTATGTTTTTCTTATAGATGTTAGCCCTGCCCAACAGCCAGGGCTACACTACAA
AAGGCAAGAATGCCCATGTAAGGAGCCCAGCAGTCTGGACAGATCCTTCTTCCTCTGCTGTTGGATGAGAGTGAGTGAGTATGCTCTGGA
CCTTATCCTTGAAAGATGATCAAAAGCGATGATGAGGGAGGCAGTCATCACGCAGGTGCTTAAAGGGACATTGTAGGAGGTACTCAAGGG
TTTGGGGGCAAAACCCTGAATCCAGCCAGTCGTGCACAGAGACACACCCACACTAGCCCAGTGGCAGTGGGGGATGTGGGATGGCAGCAG
CCAGGTATGTAGCCCTGTCACAGGACAGCTCACTGTGGTTTTGCACACTGCCTAAGGGTTAAATTGTGTTGTTGCCTTCAGTAGAAGGCA
TTTGTGGGCTGCAGAGTTGAGAGTTGGGTGAGGTTAGTCTCTCCTGAAGAAAAAGCCTATAAAAAGTGGCTAATCTTATCCCTTTTCTCT
GTATGCAGTTGGACTCGTCAGAGATAGTAAAATCATCTTTTAGTGTTTTTTTGTTGCTGATGTCTTGTACCCATTTGTTTTTTACATGGG
GTTGTAGATCGAGTTCTCAAAGGTGAAACCAGATGATCATTCTGATAAAGGAAATTTAAATTTGATACATATGCTTTGTATATTTTGATT
ACTTGTTTTCGTTTTTGACTATAAAGGAGCTTTTTTTCTTGCTCAGAGTTTACCTGGGAGATTTCACCAGTTTGACTCACCATTTGCAGA
TGTGCTTTTGTATTAAATTTAAATTTTCACATATCACATCCATTCTCAAGGTAGTTATATGCTGGAGAAGAAAAATCCTCTAGACACATG
AAGGCCCACATAGTCAAGTCTTCCAGGGCAAAGCCAGCAGCCCACCCAGGTCAGGTAGCCAGCAGGGCTCAGTTCCCCTCACTCCAGACA
CGGACCCTCCTCTTCAGGGTCTCTTGACCCAGCTTCCTTCTCTCCTTTTACCTGAGAGCACAGACCTCTCTCAGCCAGCCTGCCCAGACC
ACGGGGGGCTACTCCCATGTAGTTTGGGGAGCACTTGATCTCAGAAAAGCTCCATTGTCTGAGCAAATGGGCAGTTGTGGAGCTCAAGCC
TTTCTCCTGTGCTCAAGTCCCTTCCCCAAGCAAGGCTTCAACCTCATCTACCCACCATGTAGTTTTCTCTGGCCATTTAAGTGGGGCGGC
AGGGACATGGTTGGGCCATGCCACACCAGGGCTGGTGAGGCAACCAGTTTTGATTTTGACAGAGTGGCTGGAGGAAAAGTGGCAATCAAG
GTGCTGCTTGGTTTGCTCTGAGTGCAAATGGAACCAACAGGTTTCTGCTGCAATCTGTGTGTTCCCAGTGCCAGGTCACACCAGGAGGGG
TGGGGCAGGGCTAACCAAGTGGTCTCTGAACTCACCGAGCGTCTGCACTTGGTTGTGAAGTTAATGGGAGTACAGAGAGCGTCTGGCCTT
GGAGAGGGGTTGAGAGCCTCCTTTTTGGTTCTTCATTCCTGAGCTCTTGCCTGCCCACAAATCTGACCTCTTTGAATGGGGACGCAGTCC
TTCAACAGAGAAGTTTCTATGGCAAAGAAGTTTCTATTTAGCTCTAGATCCAGCAGAGTCATCCATTCTAACTGCCCTGAAGTCTAGAGC
AGGGGAGGGAACCCAGAGGCTGGGGATGAGACTAGGCAGACCCTGGTTACCATATGGACAAGGACAGGGGAAAGCACCCCCTTCCTCAAT
TTCTGAAAGTTCTATCTTTGGGTTCGCAGGACTTTGAGGATGATAAAGAACATATAGGTACTAGCTTGTTGTTGCTGGTCCAAAGCTTCC
ACAGCCCTGAGAATTTGGCTTTCGTGGCTGCTCTGGCAGCTGAGCGAAGGGAGGAAGGCAGCCGCTCTGGTGGGGACTCTAGGCACCTTC
CCTGCTGTCCACTTGGATAGGCGGTGAGCCCCAGGGTACTGAGAGGAGCCTGAGCATTTACCTGCCATTAGTGCCTCTTCCTTCAGGAGA
CTGGCTTGAAACGTGTGTTCATGTGCGCGTGCACACACACACATGAGCACCTGTATGTGTTAATGAATAGTTTTTCTTGGTTAATGCTTT
TTAACTTCTGTTCCTTTCCGTAAGTGGATGATTCAAAATTAACGTGACTTGGCTGGGCGCAGTGGCTCACACCTGTAATCCCAGCACTTT
GGGAGGCCAAGGGAGGCGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGATCGGCATGGTGAAACCCCGTTTCTACTAAAAATACAA
AAATTAGCCGGGCGTGGTGGTGCGCGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGAAGGAGAATCACTTGAACCCGGGAGGTGGAGGT
TGCAGTGAGCTGAGATCGTGCCACTGCACTCCAGCCTGGGCGACAGAGCGAAACTCCGTCTCAAAAAAAAAAAAAAAACTTAATGTGACT
GGAGTTAAAAGTGAAATGTCAGGTTGTTTAGTCACTGAATAGAGAGCTACAAGTGCTTGGTCTTTCCCAAGAATCAAACCTGAGTAGAAA
TACATTTAAAAGAAAAATCTACATGGTACCTATGAATCCTGTAATTTGTTTAGGGAGATCTTGTCACTCATCCCTGGTTCCTGCCCATAC
TGTTTGGTCTCGTTCTTGCAGTTTGCTTGGAACAGGGCCAGAGCCCCACATGAGATTGTCAGCAGGAGTGAGGAGCGCCAGTCCCTACTC
CTCAGCAGGGACCCAGCACAGCAATCCGGTTGTTCTCGGTTAGACTGGGTCGGGGCCAGGGGAGAAGCAGTCACCCCTGTGTAGAGGGTT
CCCGCTGTGCTTCTGAGCAGTTGCTTTGTTCAGAAGTGTTAGGAGGGTCAGATTGTGCCATAATTGTTATTAAAGAGAAAACACGCCCAC
CTTCCTTTCTCCCCTGCTGGCCATTGTTCATTGAGTTTTACTGAGGGCAGCCTTTGTGGAAGTCAGGGAGGTTGCCAAAGGCCTGTAGAT
GCCTCCTGACAAGGTCTTGATTCCTGGTTTTCTAGCACCCATTTGCATTTTGGTCTTCAGCACAAAGCCTTGTTCCCTGTGGCCGGACTT
CTGGGCAATAAGACTGGGGAGTGACTGTTGAGCAGTCTGCTGTCAGGAGAGATGGCTGAAAAGGTGATCATCTTGGTGCTAAACAAGTAA
GAGGCAACTGCCCTGTTTTTGTTTGTTTTGAGGCACAATGAAACTTTAGCCAAACTCTGCAAGAGGGTCCCATCTCCTGCCATGGCCAGG
TGTGAGAGACCAAACCGAGAAAACAGCATACTCTATCACTTAAGCCTTGGGTAGAATGGGAATTCTTTACCCTGGGTAAACGTTTTAACA
AAAAAATGGAACTTAACTTCGGTTTGGACTGTGGTCGTGCTGAGGCAGGAGTGGGGTTGCCCTCTTGGGGCTGAATCTCCAGGCCTCACG
AGGTCCCCTGTGGGGATGCTGCTATTTCTAAGATGCAAATTGCACATTTCCTAGATTTTGTATCTGTGGATTTGGATAAGGGAGGGGAAC

>20548_20548_5_CTSZ-ZHX3_CTSZ_chr20_57572658_ENST00000217131_ZHX3_chr20_39813841_ENST00000540170_length(amino acids)=236AA_BP=
MGRGRGRGGIQSGSRRGIWDSERDPERDPGAGAGPWRGAGQGGGRFCCSCCWRARRRAASTSAGDRPATGLCGGTGWLRWGAAHTPGLMS
TCPQRICPRAGTGAMWMVSTMPASPGTSTSPNTAAPAGPTPAPALWRIGSTSRGRERGPPPSCPCRTSSTAVTLAPVKGVMTCPCGTTPT

--------------------------------------------------------------
>20548_20548_6_CTSZ-ZHX3_CTSZ_chr20_57572658_ENST00000217131_ZHX3_chr20_39813841_ENST00000557816_length(transcript)=1138nt_BP=757nt
GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCG
GAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGCTTCTGCTGCTCGTGCTGCTGGCGGGCGCGG
CGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACC
CCCGGCCTCATGAGTACCTGTCCCCAGCGGATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCC
GGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG
GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGT
GGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGGACCAGGAGTGTGACAAGTTTAACCAATGTG
GGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGA
AGATGATGGCAGAAATCTATGCAAATGGTCCCATCAGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAAC
CGCCTGCCACGTGGAAGAGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGGGAGAGCTTCCAGA
ATCCTCGCAGACAGCCCAGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTT
CCTCCCACAATGTAGGACCTTTCCTTTACCTTCCAATGGATAAAATAGTTCAGAGTTCATAGTCATATTCATAGACACAGAATCAAGCTT

>20548_20548_6_CTSZ-ZHX3_CTSZ_chr20_57572658_ENST00000217131_ZHX3_chr20_39813841_ENST00000557816_length(amino acids)=236AA_BP=
MGRGRGRGGIQSGSRRGIWDSERDPERDPGAGAGPWRGAGQGGGRFCCSCCWRARRRAASTSAGDRPATGLCGGTGWLRWGAAHTPGLMS
TCPQRICPRAGTGAMWMVSTMPASPGTSTSPNTAAPAGPTPAPALWRIGSTSRGRERGPPPSCPCRTSSTAVTLAPVKGVMTCPCGTTPT

--------------------------------------------------------------
>20548_20548_7_CTSZ-ZHX3_CTSZ_chr20_57572658_ENST00000217131_ZHX3_chr20_39813841_ENST00000559234_length(transcript)=3844nt_BP=757nt
GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCG
GAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGCTTCTGCTGCTCGTGCTGCTGGCGGGCGCGG
CGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACC
CCCGGCCTCATGAGTACCTGTCCCCAGCGGATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCC
GGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG
GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGT
GGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGGACCAGGAGTGTGACAAGTTTAACCAATGTG
GGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGA
AGATGATGGCAGAAATCTATGCAAATGGTCCCATCAGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAAC
CGCCTGCCACGTGGAAGAGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGGGAGAGCTTCCAGA
ATCCTCGCAGACAGCCCAGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTT
CCTCCCACAATGTAGGACCTTTCCTTTACCTTCCAATGGATAAAATAGTTCAGAGTTCATAGTCATATTCATAGACACAGAATCAAGCTT
TTAACATATACATCCACCTCTATATGTTAAATAAAACATCAGATTATCAACACTGTCATTACGTAGAAACTTTGGTTAGCCAAGCAGTGC
ATTGTCAGTTACGTCATCTCTAAAAATGACCTGTGTCTGTTCTCTGGGGATTGCTGGGTCACAGGTGCCCCTCACCTTCCACAGTCAGGC
AGGGAAGTTATAGGCACAAAGCTACGTCTGGAACCCCTTTGTGCCCCCTTTGTGTTCCTCAAGGAAGCAGTACCTTTGAAGAGATCTCTG
CTGCATTAAGTGATGACCGGCTACGTTTCATGTCAGGCTTGCTTTGCCTTGTGGGCTACTCAGTGCAGAACCTGCTGTAACCCTCAGTTC
AAAAAATGGACTGGCAATGTGATTAGCGTTGGATGCTTTACCATTCTCTTTAGTTGTTACCGTAATTCTGCTTTTTCATGGGAGTTTGAA
TCATGGACCATAACTTTTCAGTTATCAGATCAACTAAAGAAACATTTGTTGTTAAGCCTAATGTGCTGACCTATGTGCCTGCATTTTTTT
TTTAATCTAGACATGTTTGGAGTGAGAGAAAGATGGAAAAAAGACATGGGGTAGGGACGTAAGTGGAAATCTATAGCCACAGCCTGAAGC
TTTGACCACTGCGGTTTTCAGAGCCCTTTCTCCACACTCATTTCAGAGCCTCCTATGGTTTGGGAAGGAATAACACACTGGCCCATTAGT
AAGGGTGAAGGCTGGAGGGATTTGTTGACTTCTTGGAATTATCAGAGGTAGGGTGGTCTTTAGCACAAAGACTTGCATGCAGAGATCCCT
GGCAGAACACCCAGAGTGCCCGTGGCTCCCACCCCAGGGTCTGGCCGGTGTGCTGGATGCATGCCCAAGGGTGCTGGGCATCACTGGTCC
TTGTGAGGATGCTTTTAAAGTTTTATATTTATGTCCCCAAACTTGGAAACAAGAACTCTACTTTAGCCTAACCCTCATGTCCTTTTTTGA
ATTGAGAAAATTACAGGAAATGGTGCCTTTGAAAATTAGAAAACTTGCTTACAGAGCTGTTCTAAATGGTAAATCCTCAATTTCCCCAAG
ACCGGTTGCTCTGAGAGTAGCTGGTAAAGAGGGGCGAACTAAAGACCTGTCCACCTGTAGCTCCGCTCATTTCTTAGAAACCACCTGCTT
CCCAGAGTGCCAAGCCACAAGTACCAGGCTTCGTGGGCACAGACACCTCCTGGGCTGGGCAGAGTGACAGTGCTAGAAGACCCCAGAGAG
AGGGCAAGGGCTTTGGGCAAGAAGCACTGGTGGTGTTTTAGGGACCGTCCTTCTCCCCTACCCAGGGAACTGGACCTGGCAGGGCACCGT
GCTCATGTGGCTCCAAGGACAAGCATGGCGGTGGCCCCTTCTGCCTTCCAGGAGAGGTCTTGCTTTTGAAACCAAAATCATGTTCTTCTA
AAGTGTCATCTTCTGCCCTCCCTGTCCCAATAGGGACCACATCTTATTTGTCTCAAACAGGGACTTGTGAGTACTTGGCAAGTTTTGCAG
CCTATTTTTGTATTCTTAATTTGGGGAGTAAAGATGTTTGGTCTCAAAAACCTTTGAGGAATTGCCAAGAATGGCGAGTGATTGCTTTCC
TTCAGAGAACAGACACTTGGAATTTCTCCTTTTAGTGTTTATATACGTGCAGATTAATTTATATATATATATATACACACACACATATAC
AGTATAAATACTCATTTGATTCTCGTAAAACGCGCATCTGGCGTGTGCAGTTGAGAAACTTGGTGGCACATGGGTGTTGGGGGAGTAGCC
TGTGTTGGAGGGACACCAGTGCACTAGGCAGCTGGGGCGGCCCAGGCTGAAGCCATCTCCGGGTGTCTGAGAAACCACCCAGTGCCTCAC
CTCCAGATCCTGCTGGCATCACCTCCAGAGCCCTGCATGCACTGGCTGAAGAGTTGGTCTGTGGAGAGGATTTTCTTGGTTACTTGTATT
CACGGTTAATTTACAACCCAAACAGCAAAACACAGTTGGTGGACAAGTTCATGCAGGACCTACAGTGACCCAGCCATGGGCACTAGCTCA
TCTTTCAGGTGGAAAAGTACAGTGCTGCCTGCCCTGGTATGTTTTTCTTATAGATGTTAGCCCTGCCCAACAGCCAGGGCTACACTACAA
AAGGCAAGAATGCCCATGTAAGGAGCCCAGCAGTCTGGACAGATCCTTCTTCCTCTGCTGTTGGATGAGAGTGAGTGAGTATGCTCTGGA
CCTTATCCTTGAAAGATGATCAAAAGCGATGATGAGGGAGGCAGTCATCACGCAGGTGCTTAAAGGGACATTGTAGGAGGTACTCAAGGG
TTTGGGGGCAAAACCCTGAATCCAGCCAGTCGTGCACAGAGACACACCCACACTAGCCCAGTGGCAGTGGGGGATGTGGGATGGCAGCAG
CCAGGTATGTAGCCCTGTCACAGGACAGCTCACTGTGGTTTTGCACACTGCCTAAGGGTTAAATTGTGTTGTTGCCTTCAGTAGAAGGCA
TTTGTGGGCTGCAGAGTTGAGAGTTGGGTGAGGTTAGTCTCTCCTGAAGAAAAAGCCTATAAAAAGTGGCTAATCTTATCCCTTTTCTCT
GTATGCAGTTGGACTCGTCAGAGATAGTAAAATCATCTTTTAGTGTTTTTTTGTTGCTGATGTCTTGTACCCATTTGTTTTTTACATGGG

>20548_20548_7_CTSZ-ZHX3_CTSZ_chr20_57572658_ENST00000217131_ZHX3_chr20_39813841_ENST00000559234_length(amino acids)=236AA_BP=
MGRGRGRGGIQSGSRRGIWDSERDPERDPGAGAGPWRGAGQGGGRFCCSCCWRARRRAASTSAGDRPATGLCGGTGWLRWGAAHTPGLMS
TCPQRICPRAGTGAMWMVSTMPASPGTSTSPNTAAPAGPTPAPALWRIGSTSRGRERGPPPSCPCRTSSTAVTLAPVKGVMTCPCGTTPT

--------------------------------------------------------------
>20548_20548_8_CTSZ-ZHX3_CTSZ_chr20_57572658_ENST00000217131_ZHX3_chr20_39813841_ENST00000560361_length(transcript)=1132nt_BP=757nt
GGGGTCGGCCGGGTGCTGGGCCGAGGCCGAGGCCGGGGCGGGATCCAGAGCGGGAGCCGGCGCGGGATCTGGGACTCGGAGCGGGATCCG
GAGCGGGACCCAGGAGCCGGCGCGGGGCCATGGCGAGGCGCGGGCCAGGGTGGCGGCCGCTTCTGCTGCTCGTGCTGCTGGCGGGCGCGG
CGCAGGGCGGCCTCTACTTCCGCCGGGGACAGACCTGCTACCGGCCTCTGCGGGGGGACGGGCTGGCTCCGCTGGGGCGCAGCACATACC
CCCGGCCTCATGAGTACCTGTCCCCAGCGGATCTGCCCAAGAGCTGGGACTGGCGCAATGTGGATGGTGTCAACTATGCCAGCATCACCC
GGAACCAGCACATCCCCCAATACTGCGGCTCCTGCTGGGCCCACGCCAGCACCAGCGCTATGGCGGATCGGATCAACATCAAGAGGAAGG
GAGCGTGGCCCTCCACCCTCCTGTCCGTGCAGAACGTCATCGACTGCGGTAACGCTGGCTCCTGTGAAGGGGGTAATGACCTGTCCGTGT
GGGACTACGCCCACCAGCACGGCATCCCTGACGAGACCTGCAACAACTACCAGGCCAAGGACCAGGAGTGTGACAAGTTTAACCAATGTG
GGACATGCAATGAATTCAAAGAGTGCCACGCCATCCGGAACTACACCCTCTGGAGGGTGGGAGACTACGGCTCCCTCTCTGGGAGGGAGA
AGATGATGGCAGAAATCTATGCAAATGGTCCCATCAGAAACAGACTGAATTTGATCTGATTAATGTGAAGGACTGGCCAGTCTGGGAAAC
CGCCTGCCACGTGGAAGAGCCAAACCCGACTCTCTGCTGCCACATGCCGTTCCCATGCCCGGCTGCTGGGCACCTGGGAGAGCTTCCAGA
ATCCTCGCAGACAGCCCAGAGCCTGCCGCTACCCTCGGCCTGCCCACCACCAAGCAAGCAGCAAGCAAGATGGGGTTCTCATCAGTTCTT
CCTCCCACAATGTAGGACCTTTCCTTTACCTTCCAATGGATAAAATAGTTCAGAGTTCATAGTCATATTCATAGACACAGAATCAAGCTT

>20548_20548_8_CTSZ-ZHX3_CTSZ_chr20_57572658_ENST00000217131_ZHX3_chr20_39813841_ENST00000560361_length(amino acids)=236AA_BP=
MGRGRGRGGIQSGSRRGIWDSERDPERDPGAGAGPWRGAGQGGGRFCCSCCWRARRRAASTSAGDRPATGLCGGTGWLRWGAAHTPGLMS
TCPQRICPRAGTGAMWMVSTMPASPGTSTSPNTAAPAGPTPAPALWRIGSTSRGRERGPPPSCPCRTSSTAVTLAPVKGVMTCPCGTTPT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CTSZ-ZHX3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CTSZ-ZHX3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CTSZ-ZHX3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource