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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CTTN-DSG1 (FusionGDB2 ID:20577)

Fusion Gene Summary for CTTN-DSG1

check button Fusion gene summary
Fusion gene informationFusion gene name: CTTN-DSG1
Fusion gene ID: 20577
HgeneTgene
Gene symbol

CTTN

DSG1

Gene ID

2017

1828

Gene namecortactindesmoglein 1
SynonymsEMS1CDHF4|DG1|DSG|EPKHE|EPKHIA|PPKS1|SPPK1
Cytomap

11q13.3

18q12.1

Type of geneprotein-codingprotein-coding
Descriptionsrc substrate cortactin1110020L01Rikamplaxinems1 sequence (mammary tumor and squamous cell carcinoma-associated (p80/85 src substrate)epididymis secretory sperm binding proteinoncogene EMS1desmoglein-1cadherin family member 4desmosomal glycoprotein 1pemphigus foliaceus antigen
Modification date2020032720200313
UniProtAcc

Q14247

Q02413

Ensembl transtripts involved in fusion geneENST00000301843, ENST00000346329, 
ENST00000376561, ENST00000538675, 
ENST00000527622, 		ENST00000462981, 
ENST00000257192, 
Fusion gene scores* DoF score35 X 27 X 11=103953 X 5 X 3=45
# samples 435
** MAII scorelog2(43/10395*10)=-4.59540928815627
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/45*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: CTTN [Title/Abstract] AND DSG1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCTTN(70269101)-DSG1(28906544), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneDSG1

GO:0050821

protein stabilization

7983064


check buttonFusion gene breakpoints across CTTN (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DSG1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-94-7033-01ACTTNchr11

70269101

-DSG1chr18

28906544

+
ChimerDB4LUSCTCGA-94-7033-01ACTTNchr11

70269101

+DSG1chr18

28906544

+
ChimerDB4LUSCTCGA-94-7033CTTNchr11

70269101

+DSG1chr18

28906543

+
ChimerDB4LUSCTCGA-94-7033CTTNchr11

70269101

+DSG1chr18

28906544

+


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Fusion Gene ORF analysis for CTTN-DSG1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000301843ENST00000462981CTTNchr11

70269101

+DSG1chr18

28906544

+
5CDS-intronENST00000301843ENST00000462981CTTNchr11

70269101

+DSG1chr18

28906543

+
5CDS-intronENST00000346329ENST00000462981CTTNchr11

70269101

+DSG1chr18

28906544

+
5CDS-intronENST00000346329ENST00000462981CTTNchr11

70269101

+DSG1chr18

28906543

+
5CDS-intronENST00000376561ENST00000462981CTTNchr11

70269101

+DSG1chr18

28906544

+
5CDS-intronENST00000376561ENST00000462981CTTNchr11

70269101

+DSG1chr18

28906543

+
5CDS-intronENST00000538675ENST00000462981CTTNchr11

70269101

+DSG1chr18

28906544

+
5CDS-intronENST00000538675ENST00000462981CTTNchr11

70269101

+DSG1chr18

28906543

+
In-frameENST00000301843ENST00000257192CTTNchr11

70269101

+DSG1chr18

28906544

+
In-frameENST00000301843ENST00000257192CTTNchr11

70269101

+DSG1chr18

28906543

+
In-frameENST00000346329ENST00000257192CTTNchr11

70269101

+DSG1chr18

28906544

+
In-frameENST00000346329ENST00000257192CTTNchr11

70269101

+DSG1chr18

28906543

+
In-frameENST00000376561ENST00000257192CTTNchr11

70269101

+DSG1chr18

28906544

+
In-frameENST00000376561ENST00000257192CTTNchr11

70269101

+DSG1chr18

28906543

+
In-frameENST00000538675ENST00000257192CTTNchr11

70269101

+DSG1chr18

28906544

+
In-frameENST00000538675ENST00000257192CTTNchr11

70269101

+DSG1chr18

28906543

+
intron-3CDSENST00000527622ENST00000257192CTTNchr11

70269101

+DSG1chr18

28906544

+
intron-3CDSENST00000527622ENST00000257192CTTNchr11

70269101

+DSG1chr18

28906543

+
intron-intronENST00000527622ENST00000462981CTTNchr11

70269101

+DSG1chr18

28906544

+
intron-intronENST00000527622ENST00000462981CTTNchr11

70269101

+DSG1chr18

28906543

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000346329CTTNchr1170269101+ENST00000257192DSG1chr1828906544+5939115430842551315
ENST00000301843CTTNchr1170269101+ENST00000257192DSG1chr1828906544+5948116320642641352
ENST00000376561CTTNchr1170269101+ENST00000257192DSG1chr1828906544+5802101717141181315
ENST00000538675CTTNchr1170269101+ENST00000257192DSG1chr1828906544+494215714832581036
ENST00000346329CTTNchr1170269101+ENST00000257192DSG1chr1828906543+5939115430842551315
ENST00000301843CTTNchr1170269101+ENST00000257192DSG1chr1828906543+5948116320642641352
ENST00000376561CTTNchr1170269101+ENST00000257192DSG1chr1828906543+5802101717141181315
ENST00000538675CTTNchr1170269101+ENST00000257192DSG1chr1828906543+494215714832581036

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000346329ENST00000257192CTTNchr1170269101+DSG1chr1828906544+0.0002047580.99979526
ENST00000301843ENST00000257192CTTNchr1170269101+DSG1chr1828906544+0.0001798740.9998202
ENST00000376561ENST00000257192CTTNchr1170269101+DSG1chr1828906544+0.0001647420.99983525
ENST00000538675ENST00000257192CTTNchr1170269101+DSG1chr1828906544+0.0001582610.9998417
ENST00000346329ENST00000257192CTTNchr1170269101+DSG1chr1828906543+0.0002047580.99979526
ENST00000301843ENST00000257192CTTNchr1170269101+DSG1chr1828906543+0.0001798740.9998202
ENST00000376561ENST00000257192CTTNchr1170269101+DSG1chr1828906543+0.0001647420.99983525
ENST00000538675ENST00000257192CTTNchr1170269101+DSG1chr1828906543+0.0001582610.9998417

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Fusion Genomic Features for CTTN-DSG1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CTTNchr1170269101+DSG1chr1828906543+0.0074555050.99254453
CTTNchr1170269101+DSG1chr1828906543+0.0074555050.99254453
CTTNchr1170269101+DSG1chr1828906543+0.0074555050.99254453
CTTNchr1170269101+DSG1chr1828906543+0.0074555050.99254453

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CTTN-DSG1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:70269101/chr18:28906544)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CTTN

Q14247

DSG1

Q02413

FUNCTION: Contributes to the organization of the actin cytoskeleton and cell shape (PubMed:21296879). Plays a role in the formation of lamellipodia and in cell migration. Plays a role in the regulation of neuron morphology, axon growth and formation of neuronal growth cones (By similarity). Through its interaction with CTTNBP2, involved in the regulation of neuronal spine density (By similarity). Plays a role in the invasiveness of cancer cells, and the formation of metastases (PubMed:16636290). Plays a role in focal adhesion assembly and turnover (By similarity). In complex with ABL1 and MYLK regulates cortical actin-based cytoskeletal rearrangement critical to sphingosine 1-phosphate (S1P)-mediated endothelial cell (EC) barrier enhancement (PubMed:20861316). Plays a role in intracellular protein transport and endocytosis, and in modulating the levels of potassium channels present at the cell membrane (PubMed:17959782). Plays a role in receptor-mediated endocytosis via clathrin-coated pits (By similarity). Required for stabilization of KCNH1 channels at the cell membrane (PubMed:23144454). {ECO:0000250|UniProtKB:Q60598, ECO:0000250|UniProtKB:Q66HL2, ECO:0000269|PubMed:16636290, ECO:0000269|PubMed:17959782, ECO:0000269|PubMed:21296879, ECO:0000269|PubMed:23144454}.FUNCTION: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCTTNchr11:70269101chr18:28906543ENST00000301843+1218117_153319551.0RepeatNote=Cortactin 2
HgeneCTTNchr11:70269101chr18:28906543ENST00000301843+1218154_190319551.0RepeatNote=Cortactin 3
HgeneCTTNchr11:70269101chr18:28906543ENST00000301843+1218191_227319551.0RepeatNote=Cortactin 4
HgeneCTTNchr11:70269101chr18:28906543ENST00000301843+1218228_264319551.0RepeatNote=Cortactin 5
HgeneCTTNchr11:70269101chr18:28906543ENST00000301843+1218265_301319551.0RepeatNote=Cortactin 6
HgeneCTTNchr11:70269101chr18:28906543ENST00000301843+121880_116319551.0RepeatNote=Cortactin 1
HgeneCTTNchr11:70269101chr18:28906543ENST00000346329+1117117_153282514.0RepeatNote=Cortactin 2
HgeneCTTNchr11:70269101chr18:28906543ENST00000346329+1117154_190282514.0RepeatNote=Cortactin 3
HgeneCTTNchr11:70269101chr18:28906543ENST00000346329+1117191_227282514.0RepeatNote=Cortactin 4
HgeneCTTNchr11:70269101chr18:28906543ENST00000346329+1117228_264282514.0RepeatNote=Cortactin 5
HgeneCTTNchr11:70269101chr18:28906543ENST00000346329+111780_116282514.0RepeatNote=Cortactin 1
HgeneCTTNchr11:70269101chr18:28906543ENST00000376561+1119117_153282635.0RepeatNote=Cortactin 2
HgeneCTTNchr11:70269101chr18:28906543ENST00000376561+1119154_190282635.0RepeatNote=Cortactin 3
HgeneCTTNchr11:70269101chr18:28906543ENST00000376561+1119191_227282635.0RepeatNote=Cortactin 4
HgeneCTTNchr11:70269101chr18:28906543ENST00000376561+1119228_264282635.0RepeatNote=Cortactin 5
HgeneCTTNchr11:70269101chr18:28906543ENST00000376561+111980_116282635.0RepeatNote=Cortactin 1
HgeneCTTNchr11:70269101chr18:28906544ENST00000301843+1218117_153319551.0RepeatNote=Cortactin 2
HgeneCTTNchr11:70269101chr18:28906544ENST00000301843+1218154_190319551.0RepeatNote=Cortactin 3
HgeneCTTNchr11:70269101chr18:28906544ENST00000301843+1218191_227319551.0RepeatNote=Cortactin 4
HgeneCTTNchr11:70269101chr18:28906544ENST00000301843+1218228_264319551.0RepeatNote=Cortactin 5
HgeneCTTNchr11:70269101chr18:28906544ENST00000301843+1218265_301319551.0RepeatNote=Cortactin 6
HgeneCTTNchr11:70269101chr18:28906544ENST00000301843+121880_116319551.0RepeatNote=Cortactin 1
HgeneCTTNchr11:70269101chr18:28906544ENST00000346329+1117117_153282514.0RepeatNote=Cortactin 2
HgeneCTTNchr11:70269101chr18:28906544ENST00000346329+1117154_190282514.0RepeatNote=Cortactin 3
HgeneCTTNchr11:70269101chr18:28906544ENST00000346329+1117191_227282514.0RepeatNote=Cortactin 4
HgeneCTTNchr11:70269101chr18:28906544ENST00000346329+1117228_264282514.0RepeatNote=Cortactin 5
HgeneCTTNchr11:70269101chr18:28906544ENST00000346329+111780_116282514.0RepeatNote=Cortactin 1
HgeneCTTNchr11:70269101chr18:28906544ENST00000376561+1119117_153282635.0RepeatNote=Cortactin 2
HgeneCTTNchr11:70269101chr18:28906544ENST00000376561+1119154_190282635.0RepeatNote=Cortactin 3
HgeneCTTNchr11:70269101chr18:28906544ENST00000376561+1119191_227282635.0RepeatNote=Cortactin 4
HgeneCTTNchr11:70269101chr18:28906544ENST00000376561+1119228_264282635.0RepeatNote=Cortactin 5
HgeneCTTNchr11:70269101chr18:28906544ENST00000376561+111980_116282635.0RepeatNote=Cortactin 1
TgeneDSG1chr11:70269101chr18:28906543ENST00000257192015969_1019161050.0Compositional biasNote=Gly/Ser-rich
TgeneDSG1chr11:70269101chr18:28906544ENST00000257192015969_1019161050.0Compositional biasNote=Gly/Ser-rich
TgeneDSG1chr11:70269101chr18:28906543ENST00000257192015159_270161050.0DomainCadherin 2
TgeneDSG1chr11:70269101chr18:28906543ENST00000257192015271_385161050.0DomainCadherin 3
TgeneDSG1chr11:70269101chr18:28906543ENST00000257192015386_497161050.0DomainCadherin 4
TgeneDSG1chr11:70269101chr18:28906543ENST0000025719201550_158161050.0DomainCadherin 1
TgeneDSG1chr11:70269101chr18:28906544ENST00000257192015159_270161050.0DomainCadherin 2
TgeneDSG1chr11:70269101chr18:28906544ENST00000257192015271_385161050.0DomainCadherin 3
TgeneDSG1chr11:70269101chr18:28906544ENST00000257192015386_497161050.0DomainCadherin 4
TgeneDSG1chr11:70269101chr18:28906544ENST0000025719201550_158161050.0DomainCadherin 1
TgeneDSG1chr11:70269101chr18:28906543ENST00000257192015813_839161050.0RepeatNote=Desmoglein repeat 1
TgeneDSG1chr11:70269101chr18:28906543ENST00000257192015840_869161050.0RepeatNote=Desmoglein repeat 2
TgeneDSG1chr11:70269101chr18:28906543ENST00000257192015870_899161050.0RepeatNote=Desmoglein repeat 3
TgeneDSG1chr11:70269101chr18:28906543ENST00000257192015900_927161050.0RepeatNote=Desmoglein repeat 4
TgeneDSG1chr11:70269101chr18:28906543ENST00000257192015928_956161050.0RepeatNote=Desmoglein repeat 5
TgeneDSG1chr11:70269101chr18:28906544ENST00000257192015813_839161050.0RepeatNote=Desmoglein repeat 1
TgeneDSG1chr11:70269101chr18:28906544ENST00000257192015840_869161050.0RepeatNote=Desmoglein repeat 2
TgeneDSG1chr11:70269101chr18:28906544ENST00000257192015870_899161050.0RepeatNote=Desmoglein repeat 3
TgeneDSG1chr11:70269101chr18:28906544ENST00000257192015900_927161050.0RepeatNote=Desmoglein repeat 4
TgeneDSG1chr11:70269101chr18:28906544ENST00000257192015928_956161050.0RepeatNote=Desmoglein repeat 5
TgeneDSG1chr11:70269101chr18:28906543ENST0000025719201550_548161050.0Topological domainExtracellular
TgeneDSG1chr11:70269101chr18:28906543ENST00000257192015570_1049161050.0Topological domainCytoplasmic
TgeneDSG1chr11:70269101chr18:28906544ENST0000025719201550_548161050.0Topological domainExtracellular
TgeneDSG1chr11:70269101chr18:28906544ENST00000257192015570_1049161050.0Topological domainCytoplasmic
TgeneDSG1chr11:70269101chr18:28906543ENST00000257192015549_569161050.0TransmembraneHelical
TgeneDSG1chr11:70269101chr18:28906544ENST00000257192015549_569161050.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCTTNchr11:70269101chr18:28906543ENST00000301843+1218348_401319551.0Coiled coilOntology_term=ECO:0000255
HgeneCTTNchr11:70269101chr18:28906543ENST00000346329+1117348_401282514.0Coiled coilOntology_term=ECO:0000255
HgeneCTTNchr11:70269101chr18:28906543ENST00000376561+1119348_401282635.0Coiled coilOntology_term=ECO:0000255
HgeneCTTNchr11:70269101chr18:28906544ENST00000301843+1218348_401319551.0Coiled coilOntology_term=ECO:0000255
HgeneCTTNchr11:70269101chr18:28906544ENST00000346329+1117348_401282514.0Coiled coilOntology_term=ECO:0000255
HgeneCTTNchr11:70269101chr18:28906544ENST00000376561+1119348_401282635.0Coiled coilOntology_term=ECO:0000255
HgeneCTTNchr11:70269101chr18:28906543ENST00000301843+1218492_550319551.0DomainSH3
HgeneCTTNchr11:70269101chr18:28906543ENST00000346329+1117492_550282514.0DomainSH3
HgeneCTTNchr11:70269101chr18:28906543ENST00000376561+1119492_550282635.0DomainSH3
HgeneCTTNchr11:70269101chr18:28906544ENST00000301843+1218492_550319551.0DomainSH3
HgeneCTTNchr11:70269101chr18:28906544ENST00000346329+1117492_550282514.0DomainSH3
HgeneCTTNchr11:70269101chr18:28906544ENST00000376561+1119492_550282635.0DomainSH3
HgeneCTTNchr11:70269101chr18:28906543ENST00000301843+1218302_324319551.0RepeatNote=Cortactin 7%3B truncated
HgeneCTTNchr11:70269101chr18:28906543ENST00000346329+1117265_301282514.0RepeatNote=Cortactin 6
HgeneCTTNchr11:70269101chr18:28906543ENST00000346329+1117302_324282514.0RepeatNote=Cortactin 7%3B truncated
HgeneCTTNchr11:70269101chr18:28906543ENST00000376561+1119265_301282635.0RepeatNote=Cortactin 6
HgeneCTTNchr11:70269101chr18:28906543ENST00000376561+1119302_324282635.0RepeatNote=Cortactin 7%3B truncated
HgeneCTTNchr11:70269101chr18:28906544ENST00000301843+1218302_324319551.0RepeatNote=Cortactin 7%3B truncated
HgeneCTTNchr11:70269101chr18:28906544ENST00000346329+1117265_301282514.0RepeatNote=Cortactin 6
HgeneCTTNchr11:70269101chr18:28906544ENST00000346329+1117302_324282514.0RepeatNote=Cortactin 7%3B truncated
HgeneCTTNchr11:70269101chr18:28906544ENST00000376561+1119265_301282635.0RepeatNote=Cortactin 6
HgeneCTTNchr11:70269101chr18:28906544ENST00000376561+1119302_324282635.0RepeatNote=Cortactin 7%3B truncated


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Fusion Gene Sequence for CTTN-DSG1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>20577_20577_1_CTTN-DSG1_CTTN_chr11_70269101_ENST00000301843_DSG1_chr18_28906543_ENST00000257192_length(transcript)=5948nt_BP=1163nt
GATGCGGCCCCGCCCCCGCCCTCGGAACCGGAAGTAGAGCCTGGTGCCTGGGAGCGGCTGGCGCGGCGGAATCCAGGGCCGACCCGGGCC
GGACCGACCCCAGGCGGCGACGGAATCAGTCCCCAATGCCTGGAAATTCCTCATTGGATTACTGTGTTTTAAACAGAATTTCGTGAACAG
CCTTTTATCTCCAAGCGGAAAGAAAGATGTGGAAAGCTTCAGCAGGCCACGCTGTGTCCATCGCCCAGGATGACGCGGGGGCCGATGACT
GGGAGACCGACCCTGATTTTGTGAATGATGTGAGTGAGAAGGAGCAAAGATGGGGTGCCAAGACGGTGCAGGGCTCCGGGCACCAGGAGC
ATATCAACATACACAAGCTGAGGGAGAATGTCTTTCAAGAGCATCAGACCCTTAAGGAGAAGGAACTTGAAACAGGACCAAAAGCTTCCC
ATGGCTATGGAGGGAAATTTGGTGTGGAACAAGACCGAATGGATAAGTCAGCTGTCGGCCACGAATATCAGTCGAAACTTTCCAAGCACT
GCTCGCAGGTGGACTCGGTCCGTGGCTTCGGAGGCAAGTTTGGTGTCCAGATGGACAGAGTTGATCAGTCTGCTGTAGGCTTTGAATACC
AGGGGAAGACTGAGAAGCATGCCTCCCAGAAAGACTACTCCAGTGGTTTTGGCGGCAAGTATGGCGTGCAGGCCGACCGAGTAGACAAGA
GCGCGGTGGGCTTCGACTACCAGGGCAAGACGGAGAAGCACGAGTCACAGAGAGATTACTCCAAAGGTTTCGGCGGCAAATACGGTATCG
ACAAGGACAAAGTGGATAAGAGCGCCGTTGGCTTTGAGTATCAAGGCAAAACGGAGAAGCACGAGTCCCAGAAAGACTATGTGAAAGGGT
TTGGAGGAAAATTTGGTGTGCAGACAGACAGACAAGACAAATGTGCCCTTGGCTGGGATCACCAGGAGAAATTGCAGCTGCATGAATCCC
AAAAAGATTATAAGACTGGTTTTGGAGGCAAATTCGGTGTTCAGTCGGAGAGGCAGGACTCCGCTGCTGTGGGGTTTGATTACAAGGAGA
AGCTGGCCAAGCACGAGTCCCAGCAAGACTACTCCAAAGGATTCGGCGGGAAGTATGGGGTGCAGAAGGATCGGATGGATAAGGTGGTGG
TAGAAGTTAACAGTGAATTCCGAATCCAGGTAAGAGATTATAACACTAAAAATGGCACCATCAAATGGCATTCAATCCGAAGGCAGAAAC
GTGAATGGATCAAGTTCGCAGCAGCCTGTCGTGAAGGTGAAGACAACTCAAAGAGGAACCCAATCGCCAAAATTCACTCAGATTGTGCTG
CAAACCAGCAAGTTACATACCGCATCTCTGGAGTAGGAATTGATCAGCCACCATATGGGATCTTTGTCATTAATCAGAAAACTGGTGAAA
TTAATATAACATCCATAGTTGATCGAGAGGTCACTCCTTTCTTCATTATCTACTGCCGAGCTCTGAACTCAATGGGCCAAGATTTAGAGA
GGCCTCTAGAGCTCAGAGTCAGGGTTTTGGATATAAATGACAACCCTCCAGTGTTTTCAATGGCTACATTTGCAGGACAAATAGAAGAAA
ATTCTAATGCAAATACACTGGTGATGATACTCAATGCTACTGACGCAGATGAACCGAACAATTTGAACTCAAAAATAGCCTTCAAGATTA
TAAGACAAGAACCTTCAGATTCACCAATGTTTATTATCAACAGAAATACTGGAGAAATTCGAACGATGAATAATTTTCTAGACAGAGAGC
AATACGGCCAGTATGCTCTTGCTGTAAGAGGCTCTGACCGAGATGGCGGGGCAGATGGCATGTCAGCGGAATGTGAGTGCAACATTAAAA
TCCTCGATGTCAATGATAATATCCCTTACATGGAACAGTCTTCATATACCATAGAAATTCAAGAAAATACTCTAAATTCAAATTTGCTCG
AGATTAGAGTAATTGATTTGGATGAAGAGTTCTCAGCTAACTGGATGGCAGTAATTTTCTTTATCTCTGGAAATGAAGGAAATTGGTTTG
AGATAGAAATGAATGAAAGAACAAATGTGGGAATTTTAAAGGTTGTTAAGCCCTTAGATTATGAAGCTATGCAGAGTCTGCAACTCAGTA
TTGGTGTCAGAAATAAAGCTGAATTTCATCATTCAATTATGTCTCAATATAAACTGAAAGCATCTGCAATTTCTGTGACTGTGTTAAATG
TAATTGAAGGCCCAGTGTTTCGTCCAGGTTCAAAGACATATGTTGTAACTGGTAATATGGGATCAAATGATAAAGTGGGAGACTTTGTAG
CTACTGACCTGGACACAGGTAGACCTTCAACGACTGTTAGGTATGTAATGGGAAATAATCCAGCTGACCTGCTAGCTGTTGATTCAAGAA
CAGGCAAACTCACTTTGAAAAATAAAGTTACCAAGGAACAGTACAATATGCTCGGAGGAAAATACCAAGGAACGATTCTCTCTATAGATG
ATAATCTTCAAAGAACTTGCACTGGTACAATTAATATTAACATTCAAAGTTTTGGTAATGACGACAGGACTAATACAGAGCCGAACACTA
AAATTACTACCAATACTGGCAGACAAGAAAGTACTTCTTCCACTAACTATGATACCAGCACAACTTCTACTGACTCTAGCCAAGTATATT
CTTCTGAACCCGGAAACGGAGCCAAAGATTTGTTATCAGACAATGTACATTTTGGTCCTGCTGGCATTGGACTCCTCATCATGGGATTCT
TGGTCTTAGGATTGGTCCCATTTTTGATGATCTGTTGTGATTGTGGAGGTGCTCCTCGTAGTGCAGCTGGCTTTGAGCCTGTTCCCGAAT
GTTCAGATGGAGCAATTCATTCATGGGCAGTAGAAGGACCACAGCCTGAACCCAGGGATATAACCACTGTCATACCACAAATACCACCTG
ATAACGCAAATATAATTGAATGCATTGACAACTCAGGAGTTTATACAAATGAGTATGGTGGCAGAGAAATGCAAGATCTGGGAGGAGGAG
AGAGAATGACAGGATTTGAACTAACAGAGGGAGTTAAAACTTCAGGAATGCCTGAGATATGTCAAGAATACTCTGGAACATTAAGAAGAA
ATTCTATGAGGGAATGTAGAGAAGGAGGTCTGAATATGAATTTCATGGAAAGCTACTTCTGTCAGAAAGCATATGCTTACGCAGATGAAG
ATGAAGGACGCCCATCTAATGACTGTTTGCTCATATATGACATCGAAGGTGTAGGTTCCCCTGCTGGCTCTGTGGGTTGTTGTAGCTTCA
TTGGAGAAGACCTGGATGACAGCTTCTTGGATACCCTGGGACCTAAATTTAAGAAGTTGGCAGACATCAGCCTAGGAAAAGAATCATATC
CAGACCTTGATCCTTCTTGGCCACCACAAAGCACTGAACCAGTTTGCCTTCCTCAGGAAACAGAGCCCGTTGTTAGTGGACACCCACCAA
TCTCCCCACATTTCGGCACTACCACAGTAATTTCTGAGAGCACCTATCCCTCGGGACCTGGTGTACTGCATCCTAAGCCTATTCTCGATC
CTCTGGGCTATGGTAATGTCACTGTGACCGAGTCTTACACCACCTCTGACACTCTGAAGCCCTCTGTGCACGTTCACGATAACCGACCAG
CATCAAACGTGGTAGTGACAGAGAGAGTGGTCGGCCCAATCTCTGGCGCTGATTTGCATGGAATGTTAGAGATGCCTGACTTGCGAGATG
GGTCGAATGTTATAGTGACAGAAAGGGTAATAGCACCAAGCTCTAGTCTACCCACCTCTCTGACTATCCATCATCCTAGAGAGTCTTCAA
ATGTGGTAGTGACAGAAAGAGTAATCCAACCAACTTCCGGCATGATAGGTAGTCTGAGTATGCACCCCGAGTTAGCCAATGCCCACAATG
TCATTGTGACAGAGAGGGTTGTTTCTGGTGCTGGCGTAACTGGAATTAGTGGCACCACTGGGATCAGCGGTGGCATAGGCAGCAGTGGCC
TGGTTGGCACCAGCATGGGTGCTGGGAGCGGTGCCCTGAGTGGAGCTGGCATAAGTGGTGGTGGCATTGGCCTGAGCAGCTTGGGAGGGA
CAGCCAGCATTGGCCACATGAGGAGTTCCTCTGACCATCACTTTAACCAAACCATTGGGTCCGCCTCCCCTAGCACAGCTCGAAGTCGAA
TCACAAAGTATAGTACCGTGCAATATAGCAAGTAGTCAGGACCCCAGCTCACTTTTTCATAGTCATTGTGGTTTAGATCCAATTCCCACC
ACTAAAAAACCAACAATGTGATTTATAACGCACAACTTCGTGCTCAGGTCATCTAGGAGCAAGGTGAGAAATCACAATGAGAAAAATAAA
TGGAAACACCACTGCTAGGGGAGAGCTCTCCTTAGCATTCATAAACTTTTCTCTTATATTAGGACTAAGGAACTAAAACTTGAGGCAGAG
TCTTCTTTGTGCCTGAGTGGCCTGTAGTCCATCTCCAGCATGTAACTGGCCTTACGATGGCAATTGGCATCATTCTCCTTGCTCTGTTTT
GCTTTTCCATATAGCTCGAGCAAAATTCAAAAAGAACTAAATATGCAATATATGTTCATATCTATGGGAAAAATCTAAAATGTGTGCCAG
ATGCCCTGTTGGTTTCACAGATAACATAAATAAAAATTCAACCACAGATTTATACAAGGGTTAACCATTTTTTTTAAGTTTGACTACATA
GTCAAGTCCACAAGCCATCAAGCACTCCTACCTTAATTATTGCACTAGAGAAAATAAATTCCAAATTAGGAAGTGTTTCCTAGGAGGAAA
ATTCCATTAGAGAGTGGCAATAGGATGAGGTTTCTTCAGGGTAAACTAGCAATGCCTGAGCCTGAACCTTAATGTGGGGCCTCAGTTAAA
TCTCCTGTGGAGTCAAGGATTCTTCTGATTCTAGTGTGTGTTTAGTGATAGATGTAGTCTTGACGAATATTGCTTACTGGTGAGGTTGAG
GAATATCACACTCGTCTTTCCCTTTACCACTGTGGTTTTGACTTAAGAAAGCAAAACTCACTAAGTTTACTTCTCGAATTGAAGCAAGTG
AGGCCTGACATGGTTGTCATCACTAGTGGCAAATGACCTTCCAAGTAAGCAGATGGGAACTGAATTGTGTTTTCAGGTTTTGTTTTTAGT
AGGTGATATTCATTCGTATCCAGCTCTTTATTACATAGCTCTGAAGTTAAAATGATTTACATAGGCCGAGCTGTGGACAAAAAAAAAAGA
AGCAGCAGCTTGTAGTATGCTTAAGCTTTGGGGAATTTTTTTTTAAGGGGATCTAAAAAAATGTTTTTAGAACATGTAAAATGTTTAATG
GTGAAAGTTGGAAAAGAATTCTTCTGTAAAGTAATACCATGCTAATTATTCGCTTTTAGTAAGTAAAGTAGTGGTTGCTTTAGCAAACCT
CTGCTGCCATTTTGCAGGAATCAACCAGGAACCTTTAGCAGAATTGACAATATGGTGTTGATAAGCATGAAATAATAATAGAAACCTATT
CTGCTAGTTTATCTCACCCTCTAATTTTTCTCACTAGCATAAATTTTAAATTCCTGATTTGATTTGTCAATAAGATCTTGGCTTATATAT
GCTGATTTATAGGTAGTGTCCAAATTATATAGTATAACATATTTTTCTAGTTTCAAAATTTAGTAATGTCCTATTTATGATATATCATTT
CTGTGTGTTTGCTATGTAGTATTACCCAATTAAAAATCTCTAAAAAGAATTAAAGCATTCTAAGAAAAAGGTAAATTTACTATTGCATGG
TACAGAAATTTTTTCTTTCTTAAATACAATGTTACTATAAGCTCACTAAAATGAAACTCTATATGACAAAATAAAATTAGAAAAAAATTT

>20577_20577_1_CTTN-DSG1_CTTN_chr11_70269101_ENST00000301843_DSG1_chr18_28906543_ENST00000257192_length(amino acids)=1352AA_BP=319
MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRENVFQEHQTLKEKELETGPKASHGYGGKFGV
EQDRMDKSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHESQKDYKTGFG
GKFGVQSERQDSAAVGFDYKEKLAKHESQQDYSKGFGGKYGVQKDRMDKVVVEVNSEFRIQVRDYNTKNGTIKWHSIRRQKREWIKFAAA
CREGEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQPPYGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRV
LDINDNPPVFSMATFAGQIEENSNANTLVMILNATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAV
RGSDRDGGADGMSAECECNIKILDVNDNIPYMEQSSYTIEIQENTLNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTN
VGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHSIMSQYKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRP
STTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYNMLGGKYQGTILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQ
ESTSSTNYDTSTTSTDSSQVYSSEPGNGAKDLLSDNVHFGPAGIGLLIMGFLVLGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSW
AVEGPQPEPRDITTVIPQIPPDNANIIECIDNSGVYTNEYGGREMQDLGGGERMTGFELTEGVKTSGMPEICQEYSGTLRRNSMRECREG
GLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLGKESYPDLDPSWPP
QSTEPVCLPQETEPVVSGHPPISPHFGTTTVISESTYPSGPGVLHPKPILDPLGYGNVTVTESYTTSDTLKPSVHVHDNRPASNVVVTER
VVGPISGADLHGMLEMPDLRDGSNVIVTERVIAPSSSLPTSLTIHHPRESSNVVVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVS
GAGVTGISGTTGISGGIGSSGLVGTSMGAGSGALSGAGISGGGIGLSSLGGTASIGHMRSSSDHHFNQTIGSASPSTARSRITKYSTVQY

--------------------------------------------------------------
>20577_20577_2_CTTN-DSG1_CTTN_chr11_70269101_ENST00000301843_DSG1_chr18_28906544_ENST00000257192_length(transcript)=5948nt_BP=1163nt
GATGCGGCCCCGCCCCCGCCCTCGGAACCGGAAGTAGAGCCTGGTGCCTGGGAGCGGCTGGCGCGGCGGAATCCAGGGCCGACCCGGGCC
GGACCGACCCCAGGCGGCGACGGAATCAGTCCCCAATGCCTGGAAATTCCTCATTGGATTACTGTGTTTTAAACAGAATTTCGTGAACAG
CCTTTTATCTCCAAGCGGAAAGAAAGATGTGGAAAGCTTCAGCAGGCCACGCTGTGTCCATCGCCCAGGATGACGCGGGGGCCGATGACT
GGGAGACCGACCCTGATTTTGTGAATGATGTGAGTGAGAAGGAGCAAAGATGGGGTGCCAAGACGGTGCAGGGCTCCGGGCACCAGGAGC
ATATCAACATACACAAGCTGAGGGAGAATGTCTTTCAAGAGCATCAGACCCTTAAGGAGAAGGAACTTGAAACAGGACCAAAAGCTTCCC
ATGGCTATGGAGGGAAATTTGGTGTGGAACAAGACCGAATGGATAAGTCAGCTGTCGGCCACGAATATCAGTCGAAACTTTCCAAGCACT
GCTCGCAGGTGGACTCGGTCCGTGGCTTCGGAGGCAAGTTTGGTGTCCAGATGGACAGAGTTGATCAGTCTGCTGTAGGCTTTGAATACC
AGGGGAAGACTGAGAAGCATGCCTCCCAGAAAGACTACTCCAGTGGTTTTGGCGGCAAGTATGGCGTGCAGGCCGACCGAGTAGACAAGA
GCGCGGTGGGCTTCGACTACCAGGGCAAGACGGAGAAGCACGAGTCACAGAGAGATTACTCCAAAGGTTTCGGCGGCAAATACGGTATCG
ACAAGGACAAAGTGGATAAGAGCGCCGTTGGCTTTGAGTATCAAGGCAAAACGGAGAAGCACGAGTCCCAGAAAGACTATGTGAAAGGGT
TTGGAGGAAAATTTGGTGTGCAGACAGACAGACAAGACAAATGTGCCCTTGGCTGGGATCACCAGGAGAAATTGCAGCTGCATGAATCCC
AAAAAGATTATAAGACTGGTTTTGGAGGCAAATTCGGTGTTCAGTCGGAGAGGCAGGACTCCGCTGCTGTGGGGTTTGATTACAAGGAGA
AGCTGGCCAAGCACGAGTCCCAGCAAGACTACTCCAAAGGATTCGGCGGGAAGTATGGGGTGCAGAAGGATCGGATGGATAAGGTGGTGG
TAGAAGTTAACAGTGAATTCCGAATCCAGGTAAGAGATTATAACACTAAAAATGGCACCATCAAATGGCATTCAATCCGAAGGCAGAAAC
GTGAATGGATCAAGTTCGCAGCAGCCTGTCGTGAAGGTGAAGACAACTCAAAGAGGAACCCAATCGCCAAAATTCACTCAGATTGTGCTG
CAAACCAGCAAGTTACATACCGCATCTCTGGAGTAGGAATTGATCAGCCACCATATGGGATCTTTGTCATTAATCAGAAAACTGGTGAAA
TTAATATAACATCCATAGTTGATCGAGAGGTCACTCCTTTCTTCATTATCTACTGCCGAGCTCTGAACTCAATGGGCCAAGATTTAGAGA
GGCCTCTAGAGCTCAGAGTCAGGGTTTTGGATATAAATGACAACCCTCCAGTGTTTTCAATGGCTACATTTGCAGGACAAATAGAAGAAA
ATTCTAATGCAAATACACTGGTGATGATACTCAATGCTACTGACGCAGATGAACCGAACAATTTGAACTCAAAAATAGCCTTCAAGATTA
TAAGACAAGAACCTTCAGATTCACCAATGTTTATTATCAACAGAAATACTGGAGAAATTCGAACGATGAATAATTTTCTAGACAGAGAGC
AATACGGCCAGTATGCTCTTGCTGTAAGAGGCTCTGACCGAGATGGCGGGGCAGATGGCATGTCAGCGGAATGTGAGTGCAACATTAAAA
TCCTCGATGTCAATGATAATATCCCTTACATGGAACAGTCTTCATATACCATAGAAATTCAAGAAAATACTCTAAATTCAAATTTGCTCG
AGATTAGAGTAATTGATTTGGATGAAGAGTTCTCAGCTAACTGGATGGCAGTAATTTTCTTTATCTCTGGAAATGAAGGAAATTGGTTTG
AGATAGAAATGAATGAAAGAACAAATGTGGGAATTTTAAAGGTTGTTAAGCCCTTAGATTATGAAGCTATGCAGAGTCTGCAACTCAGTA
TTGGTGTCAGAAATAAAGCTGAATTTCATCATTCAATTATGTCTCAATATAAACTGAAAGCATCTGCAATTTCTGTGACTGTGTTAAATG
TAATTGAAGGCCCAGTGTTTCGTCCAGGTTCAAAGACATATGTTGTAACTGGTAATATGGGATCAAATGATAAAGTGGGAGACTTTGTAG
CTACTGACCTGGACACAGGTAGACCTTCAACGACTGTTAGGTATGTAATGGGAAATAATCCAGCTGACCTGCTAGCTGTTGATTCAAGAA
CAGGCAAACTCACTTTGAAAAATAAAGTTACCAAGGAACAGTACAATATGCTCGGAGGAAAATACCAAGGAACGATTCTCTCTATAGATG
ATAATCTTCAAAGAACTTGCACTGGTACAATTAATATTAACATTCAAAGTTTTGGTAATGACGACAGGACTAATACAGAGCCGAACACTA
AAATTACTACCAATACTGGCAGACAAGAAAGTACTTCTTCCACTAACTATGATACCAGCACAACTTCTACTGACTCTAGCCAAGTATATT
CTTCTGAACCCGGAAACGGAGCCAAAGATTTGTTATCAGACAATGTACATTTTGGTCCTGCTGGCATTGGACTCCTCATCATGGGATTCT
TGGTCTTAGGATTGGTCCCATTTTTGATGATCTGTTGTGATTGTGGAGGTGCTCCTCGTAGTGCAGCTGGCTTTGAGCCTGTTCCCGAAT
GTTCAGATGGAGCAATTCATTCATGGGCAGTAGAAGGACCACAGCCTGAACCCAGGGATATAACCACTGTCATACCACAAATACCACCTG
ATAACGCAAATATAATTGAATGCATTGACAACTCAGGAGTTTATACAAATGAGTATGGTGGCAGAGAAATGCAAGATCTGGGAGGAGGAG
AGAGAATGACAGGATTTGAACTAACAGAGGGAGTTAAAACTTCAGGAATGCCTGAGATATGTCAAGAATACTCTGGAACATTAAGAAGAA
ATTCTATGAGGGAATGTAGAGAAGGAGGTCTGAATATGAATTTCATGGAAAGCTACTTCTGTCAGAAAGCATATGCTTACGCAGATGAAG
ATGAAGGACGCCCATCTAATGACTGTTTGCTCATATATGACATCGAAGGTGTAGGTTCCCCTGCTGGCTCTGTGGGTTGTTGTAGCTTCA
TTGGAGAAGACCTGGATGACAGCTTCTTGGATACCCTGGGACCTAAATTTAAGAAGTTGGCAGACATCAGCCTAGGAAAAGAATCATATC
CAGACCTTGATCCTTCTTGGCCACCACAAAGCACTGAACCAGTTTGCCTTCCTCAGGAAACAGAGCCCGTTGTTAGTGGACACCCACCAA
TCTCCCCACATTTCGGCACTACCACAGTAATTTCTGAGAGCACCTATCCCTCGGGACCTGGTGTACTGCATCCTAAGCCTATTCTCGATC
CTCTGGGCTATGGTAATGTCACTGTGACCGAGTCTTACACCACCTCTGACACTCTGAAGCCCTCTGTGCACGTTCACGATAACCGACCAG
CATCAAACGTGGTAGTGACAGAGAGAGTGGTCGGCCCAATCTCTGGCGCTGATTTGCATGGAATGTTAGAGATGCCTGACTTGCGAGATG
GGTCGAATGTTATAGTGACAGAAAGGGTAATAGCACCAAGCTCTAGTCTACCCACCTCTCTGACTATCCATCATCCTAGAGAGTCTTCAA
ATGTGGTAGTGACAGAAAGAGTAATCCAACCAACTTCCGGCATGATAGGTAGTCTGAGTATGCACCCCGAGTTAGCCAATGCCCACAATG
TCATTGTGACAGAGAGGGTTGTTTCTGGTGCTGGCGTAACTGGAATTAGTGGCACCACTGGGATCAGCGGTGGCATAGGCAGCAGTGGCC
TGGTTGGCACCAGCATGGGTGCTGGGAGCGGTGCCCTGAGTGGAGCTGGCATAAGTGGTGGTGGCATTGGCCTGAGCAGCTTGGGAGGGA
CAGCCAGCATTGGCCACATGAGGAGTTCCTCTGACCATCACTTTAACCAAACCATTGGGTCCGCCTCCCCTAGCACAGCTCGAAGTCGAA
TCACAAAGTATAGTACCGTGCAATATAGCAAGTAGTCAGGACCCCAGCTCACTTTTTCATAGTCATTGTGGTTTAGATCCAATTCCCACC
ACTAAAAAACCAACAATGTGATTTATAACGCACAACTTCGTGCTCAGGTCATCTAGGAGCAAGGTGAGAAATCACAATGAGAAAAATAAA
TGGAAACACCACTGCTAGGGGAGAGCTCTCCTTAGCATTCATAAACTTTTCTCTTATATTAGGACTAAGGAACTAAAACTTGAGGCAGAG
TCTTCTTTGTGCCTGAGTGGCCTGTAGTCCATCTCCAGCATGTAACTGGCCTTACGATGGCAATTGGCATCATTCTCCTTGCTCTGTTTT
GCTTTTCCATATAGCTCGAGCAAAATTCAAAAAGAACTAAATATGCAATATATGTTCATATCTATGGGAAAAATCTAAAATGTGTGCCAG
ATGCCCTGTTGGTTTCACAGATAACATAAATAAAAATTCAACCACAGATTTATACAAGGGTTAACCATTTTTTTTAAGTTTGACTACATA
GTCAAGTCCACAAGCCATCAAGCACTCCTACCTTAATTATTGCACTAGAGAAAATAAATTCCAAATTAGGAAGTGTTTCCTAGGAGGAAA
ATTCCATTAGAGAGTGGCAATAGGATGAGGTTTCTTCAGGGTAAACTAGCAATGCCTGAGCCTGAACCTTAATGTGGGGCCTCAGTTAAA
TCTCCTGTGGAGTCAAGGATTCTTCTGATTCTAGTGTGTGTTTAGTGATAGATGTAGTCTTGACGAATATTGCTTACTGGTGAGGTTGAG
GAATATCACACTCGTCTTTCCCTTTACCACTGTGGTTTTGACTTAAGAAAGCAAAACTCACTAAGTTTACTTCTCGAATTGAAGCAAGTG
AGGCCTGACATGGTTGTCATCACTAGTGGCAAATGACCTTCCAAGTAAGCAGATGGGAACTGAATTGTGTTTTCAGGTTTTGTTTTTAGT
AGGTGATATTCATTCGTATCCAGCTCTTTATTACATAGCTCTGAAGTTAAAATGATTTACATAGGCCGAGCTGTGGACAAAAAAAAAAGA
AGCAGCAGCTTGTAGTATGCTTAAGCTTTGGGGAATTTTTTTTTAAGGGGATCTAAAAAAATGTTTTTAGAACATGTAAAATGTTTAATG
GTGAAAGTTGGAAAAGAATTCTTCTGTAAAGTAATACCATGCTAATTATTCGCTTTTAGTAAGTAAAGTAGTGGTTGCTTTAGCAAACCT
CTGCTGCCATTTTGCAGGAATCAACCAGGAACCTTTAGCAGAATTGACAATATGGTGTTGATAAGCATGAAATAATAATAGAAACCTATT
CTGCTAGTTTATCTCACCCTCTAATTTTTCTCACTAGCATAAATTTTAAATTCCTGATTTGATTTGTCAATAAGATCTTGGCTTATATAT
GCTGATTTATAGGTAGTGTCCAAATTATATAGTATAACATATTTTTCTAGTTTCAAAATTTAGTAATGTCCTATTTATGATATATCATTT
CTGTGTGTTTGCTATGTAGTATTACCCAATTAAAAATCTCTAAAAAGAATTAAAGCATTCTAAGAAAAAGGTAAATTTACTATTGCATGG
TACAGAAATTTTTTCTTTCTTAAATACAATGTTACTATAAGCTCACTAAAATGAAACTCTATATGACAAAATAAAATTAGAAAAAAATTT

>20577_20577_2_CTTN-DSG1_CTTN_chr11_70269101_ENST00000301843_DSG1_chr18_28906544_ENST00000257192_length(amino acids)=1352AA_BP=319
MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRENVFQEHQTLKEKELETGPKASHGYGGKFGV
EQDRMDKSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHESQKDYKTGFG
GKFGVQSERQDSAAVGFDYKEKLAKHESQQDYSKGFGGKYGVQKDRMDKVVVEVNSEFRIQVRDYNTKNGTIKWHSIRRQKREWIKFAAA
CREGEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQPPYGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRV
LDINDNPPVFSMATFAGQIEENSNANTLVMILNATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAV
RGSDRDGGADGMSAECECNIKILDVNDNIPYMEQSSYTIEIQENTLNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTN
VGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHSIMSQYKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRP
STTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYNMLGGKYQGTILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQ
ESTSSTNYDTSTTSTDSSQVYSSEPGNGAKDLLSDNVHFGPAGIGLLIMGFLVLGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSW
AVEGPQPEPRDITTVIPQIPPDNANIIECIDNSGVYTNEYGGREMQDLGGGERMTGFELTEGVKTSGMPEICQEYSGTLRRNSMRECREG
GLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLGKESYPDLDPSWPP
QSTEPVCLPQETEPVVSGHPPISPHFGTTTVISESTYPSGPGVLHPKPILDPLGYGNVTVTESYTTSDTLKPSVHVHDNRPASNVVVTER
VVGPISGADLHGMLEMPDLRDGSNVIVTERVIAPSSSLPTSLTIHHPRESSNVVVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVS
GAGVTGISGTTGISGGIGSSGLVGTSMGAGSGALSGAGISGGGIGLSSLGGTASIGHMRSSSDHHFNQTIGSASPSTARSRITKYSTVQY

--------------------------------------------------------------
>20577_20577_3_CTTN-DSG1_CTTN_chr11_70269101_ENST00000346329_DSG1_chr18_28906543_ENST00000257192_length(transcript)=5939nt_BP=1154nt
GGCCGGGCTAGCGCTTAGCCAGCTGCGGGCGGACCCCCGGGACTCTTGCGGGCCAAGACGCGGGAGGAGGCGGGGCAGGGGGCGGGGTCG
CGCGGGGACCCGGATGCGGCCCCGCCCCCGCCCTCGGAACCGGAAGTAGAGCCTGGTGCCTGGGAGCGGCTGGCGCGGCGGAATCCAGGG
CCGACCCGGGCCGGACCGACCCCAGGCGGCGACGGAATCAGTCCCCAATGCCTGGAAATTCCTCATTGGATTACTGTGTTTTAAACAGAA
TTTCGTGAACAGCCTTTTATCTCCAAGCGGAAAGAAAGATGTGGAAAGCTTCAGCAGGCCACGCTGTGTCCATCGCCCAGGATGACGCGG
GGGCCGATGACTGGGAGACCGACCCTGATTTTGTGAATGATGTGAGTGAGAAGGAGCAAAGATGGGGTGCCAAGACGGTGCAGGGCTCCG
GGCACCAGGAGCATATCAACATACACAAGCTGAGGGAGAATGTCTTTCAAGAGCATCAGACCCTTAAGGAGAAGGAACTTGAAACAGGAC
CAAAAGCTTCCCATGGCTATGGAGGGAAATTTGGTGTGGAACAAGACCGAATGGATAAGTCAGCTGTCGGCCACGAATATCAGTCGAAAC
TTTCCAAGCACTGCTCGCAGGTGGACTCGGTCCGTGGCTTCGGAGGCAAGTTTGGTGTCCAGATGGACAGAGTTGATCAGTCTGCTGTAG
GCTTTGAATACCAGGGGAAGACTGAGAAGCATGCCTCCCAGAAAGACTACTCCAGTGGTTTTGGCGGCAAGTATGGCGTGCAGGCCGACC
GAGTAGACAAGAGCGCGGTGGGCTTCGACTACCAGGGCAAGACGGAGAAGCACGAGTCACAGAGAGATTACTCCAAAGGTTTCGGCGGCA
AATACGGTATCGACAAGGACAAAGTGGATAAGAGCGCCGTTGGCTTTGAGTATCAAGGCAAAACGGAGAAGCACGAGTCCCAGAAAGACT
ATGTGAAAGGGTTTGGAGGAAAATTTGGTGTGCAGACAGACAGACAAGACAAATGTGCCCTTGGCTGGGATCACCAGGAGAAATTGCAGC
TGCATGAATCCCAAAAAGACTACTCCAAAGGATTCGGCGGGAAGTATGGGGTGCAGAAGGATCGGATGGATAAGGTGGTGGTAGAAGTTA
ACAGTGAATTCCGAATCCAGGTAAGAGATTATAACACTAAAAATGGCACCATCAAATGGCATTCAATCCGAAGGCAGAAACGTGAATGGA
TCAAGTTCGCAGCAGCCTGTCGTGAAGGTGAAGACAACTCAAAGAGGAACCCAATCGCCAAAATTCACTCAGATTGTGCTGCAAACCAGC
AAGTTACATACCGCATCTCTGGAGTAGGAATTGATCAGCCACCATATGGGATCTTTGTCATTAATCAGAAAACTGGTGAAATTAATATAA
CATCCATAGTTGATCGAGAGGTCACTCCTTTCTTCATTATCTACTGCCGAGCTCTGAACTCAATGGGCCAAGATTTAGAGAGGCCTCTAG
AGCTCAGAGTCAGGGTTTTGGATATAAATGACAACCCTCCAGTGTTTTCAATGGCTACATTTGCAGGACAAATAGAAGAAAATTCTAATG
CAAATACACTGGTGATGATACTCAATGCTACTGACGCAGATGAACCGAACAATTTGAACTCAAAAATAGCCTTCAAGATTATAAGACAAG
AACCTTCAGATTCACCAATGTTTATTATCAACAGAAATACTGGAGAAATTCGAACGATGAATAATTTTCTAGACAGAGAGCAATACGGCC
AGTATGCTCTTGCTGTAAGAGGCTCTGACCGAGATGGCGGGGCAGATGGCATGTCAGCGGAATGTGAGTGCAACATTAAAATCCTCGATG
TCAATGATAATATCCCTTACATGGAACAGTCTTCATATACCATAGAAATTCAAGAAAATACTCTAAATTCAAATTTGCTCGAGATTAGAG
TAATTGATTTGGATGAAGAGTTCTCAGCTAACTGGATGGCAGTAATTTTCTTTATCTCTGGAAATGAAGGAAATTGGTTTGAGATAGAAA
TGAATGAAAGAACAAATGTGGGAATTTTAAAGGTTGTTAAGCCCTTAGATTATGAAGCTATGCAGAGTCTGCAACTCAGTATTGGTGTCA
GAAATAAAGCTGAATTTCATCATTCAATTATGTCTCAATATAAACTGAAAGCATCTGCAATTTCTGTGACTGTGTTAAATGTAATTGAAG
GCCCAGTGTTTCGTCCAGGTTCAAAGACATATGTTGTAACTGGTAATATGGGATCAAATGATAAAGTGGGAGACTTTGTAGCTACTGACC
TGGACACAGGTAGACCTTCAACGACTGTTAGGTATGTAATGGGAAATAATCCAGCTGACCTGCTAGCTGTTGATTCAAGAACAGGCAAAC
TCACTTTGAAAAATAAAGTTACCAAGGAACAGTACAATATGCTCGGAGGAAAATACCAAGGAACGATTCTCTCTATAGATGATAATCTTC
AAAGAACTTGCACTGGTACAATTAATATTAACATTCAAAGTTTTGGTAATGACGACAGGACTAATACAGAGCCGAACACTAAAATTACTA
CCAATACTGGCAGACAAGAAAGTACTTCTTCCACTAACTATGATACCAGCACAACTTCTACTGACTCTAGCCAAGTATATTCTTCTGAAC
CCGGAAACGGAGCCAAAGATTTGTTATCAGACAATGTACATTTTGGTCCTGCTGGCATTGGACTCCTCATCATGGGATTCTTGGTCTTAG
GATTGGTCCCATTTTTGATGATCTGTTGTGATTGTGGAGGTGCTCCTCGTAGTGCAGCTGGCTTTGAGCCTGTTCCCGAATGTTCAGATG
GAGCAATTCATTCATGGGCAGTAGAAGGACCACAGCCTGAACCCAGGGATATAACCACTGTCATACCACAAATACCACCTGATAACGCAA
ATATAATTGAATGCATTGACAACTCAGGAGTTTATACAAATGAGTATGGTGGCAGAGAAATGCAAGATCTGGGAGGAGGAGAGAGAATGA
CAGGATTTGAACTAACAGAGGGAGTTAAAACTTCAGGAATGCCTGAGATATGTCAAGAATACTCTGGAACATTAAGAAGAAATTCTATGA
GGGAATGTAGAGAAGGAGGTCTGAATATGAATTTCATGGAAAGCTACTTCTGTCAGAAAGCATATGCTTACGCAGATGAAGATGAAGGAC
GCCCATCTAATGACTGTTTGCTCATATATGACATCGAAGGTGTAGGTTCCCCTGCTGGCTCTGTGGGTTGTTGTAGCTTCATTGGAGAAG
ACCTGGATGACAGCTTCTTGGATACCCTGGGACCTAAATTTAAGAAGTTGGCAGACATCAGCCTAGGAAAAGAATCATATCCAGACCTTG
ATCCTTCTTGGCCACCACAAAGCACTGAACCAGTTTGCCTTCCTCAGGAAACAGAGCCCGTTGTTAGTGGACACCCACCAATCTCCCCAC
ATTTCGGCACTACCACAGTAATTTCTGAGAGCACCTATCCCTCGGGACCTGGTGTACTGCATCCTAAGCCTATTCTCGATCCTCTGGGCT
ATGGTAATGTCACTGTGACCGAGTCTTACACCACCTCTGACACTCTGAAGCCCTCTGTGCACGTTCACGATAACCGACCAGCATCAAACG
TGGTAGTGACAGAGAGAGTGGTCGGCCCAATCTCTGGCGCTGATTTGCATGGAATGTTAGAGATGCCTGACTTGCGAGATGGGTCGAATG
TTATAGTGACAGAAAGGGTAATAGCACCAAGCTCTAGTCTACCCACCTCTCTGACTATCCATCATCCTAGAGAGTCTTCAAATGTGGTAG
TGACAGAAAGAGTAATCCAACCAACTTCCGGCATGATAGGTAGTCTGAGTATGCACCCCGAGTTAGCCAATGCCCACAATGTCATTGTGA
CAGAGAGGGTTGTTTCTGGTGCTGGCGTAACTGGAATTAGTGGCACCACTGGGATCAGCGGTGGCATAGGCAGCAGTGGCCTGGTTGGCA
CCAGCATGGGTGCTGGGAGCGGTGCCCTGAGTGGAGCTGGCATAAGTGGTGGTGGCATTGGCCTGAGCAGCTTGGGAGGGACAGCCAGCA
TTGGCCACATGAGGAGTTCCTCTGACCATCACTTTAACCAAACCATTGGGTCCGCCTCCCCTAGCACAGCTCGAAGTCGAATCACAAAGT
ATAGTACCGTGCAATATAGCAAGTAGTCAGGACCCCAGCTCACTTTTTCATAGTCATTGTGGTTTAGATCCAATTCCCACCACTAAAAAA
CCAACAATGTGATTTATAACGCACAACTTCGTGCTCAGGTCATCTAGGAGCAAGGTGAGAAATCACAATGAGAAAAATAAATGGAAACAC
CACTGCTAGGGGAGAGCTCTCCTTAGCATTCATAAACTTTTCTCTTATATTAGGACTAAGGAACTAAAACTTGAGGCAGAGTCTTCTTTG
TGCCTGAGTGGCCTGTAGTCCATCTCCAGCATGTAACTGGCCTTACGATGGCAATTGGCATCATTCTCCTTGCTCTGTTTTGCTTTTCCA
TATAGCTCGAGCAAAATTCAAAAAGAACTAAATATGCAATATATGTTCATATCTATGGGAAAAATCTAAAATGTGTGCCAGATGCCCTGT
TGGTTTCACAGATAACATAAATAAAAATTCAACCACAGATTTATACAAGGGTTAACCATTTTTTTTAAGTTTGACTACATAGTCAAGTCC
ACAAGCCATCAAGCACTCCTACCTTAATTATTGCACTAGAGAAAATAAATTCCAAATTAGGAAGTGTTTCCTAGGAGGAAAATTCCATTA
GAGAGTGGCAATAGGATGAGGTTTCTTCAGGGTAAACTAGCAATGCCTGAGCCTGAACCTTAATGTGGGGCCTCAGTTAAATCTCCTGTG
GAGTCAAGGATTCTTCTGATTCTAGTGTGTGTTTAGTGATAGATGTAGTCTTGACGAATATTGCTTACTGGTGAGGTTGAGGAATATCAC
ACTCGTCTTTCCCTTTACCACTGTGGTTTTGACTTAAGAAAGCAAAACTCACTAAGTTTACTTCTCGAATTGAAGCAAGTGAGGCCTGAC
ATGGTTGTCATCACTAGTGGCAAATGACCTTCCAAGTAAGCAGATGGGAACTGAATTGTGTTTTCAGGTTTTGTTTTTAGTAGGTGATAT
TCATTCGTATCCAGCTCTTTATTACATAGCTCTGAAGTTAAAATGATTTACATAGGCCGAGCTGTGGACAAAAAAAAAAGAAGCAGCAGC
TTGTAGTATGCTTAAGCTTTGGGGAATTTTTTTTTAAGGGGATCTAAAAAAATGTTTTTAGAACATGTAAAATGTTTAATGGTGAAAGTT
GGAAAAGAATTCTTCTGTAAAGTAATACCATGCTAATTATTCGCTTTTAGTAAGTAAAGTAGTGGTTGCTTTAGCAAACCTCTGCTGCCA
TTTTGCAGGAATCAACCAGGAACCTTTAGCAGAATTGACAATATGGTGTTGATAAGCATGAAATAATAATAGAAACCTATTCTGCTAGTT
TATCTCACCCTCTAATTTTTCTCACTAGCATAAATTTTAAATTCCTGATTTGATTTGTCAATAAGATCTTGGCTTATATATGCTGATTTA
TAGGTAGTGTCCAAATTATATAGTATAACATATTTTTCTAGTTTCAAAATTTAGTAATGTCCTATTTATGATATATCATTTCTGTGTGTT
TGCTATGTAGTATTACCCAATTAAAAATCTCTAAAAAGAATTAAAGCATTCTAAGAAAAAGGTAAATTTACTATTGCATGGTACAGAAAT

>20577_20577_3_CTTN-DSG1_CTTN_chr11_70269101_ENST00000346329_DSG1_chr18_28906543_ENST00000257192_length(amino acids)=1315AA_BP=282
MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRENVFQEHQTLKEKELETGPKASHGYGGKFGV
EQDRMDKSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHESQKDYSKGFG
GKYGVQKDRMDKVVVEVNSEFRIQVRDYNTKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQ
PPYGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLVMILNATDA
DEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRDGGADGMSAECECNIKILDVNDNIPYMEQSSY
TIEIQENTLNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHSIMSQ
YKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYN
MLGGKYQGTILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTSTDSSQVYSSEPGNGAKDLLSDNV
HFGPAGIGLLIMGFLVLGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSWAVEGPQPEPRDITTVIPQIPPDNANIIECIDNSGVYT
NEYGGREMQDLGGGERMTGFELTEGVKTSGMPEICQEYSGTLRRNSMRECREGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIE
GVGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLGKESYPDLDPSWPPQSTEPVCLPQETEPVVSGHPPISPHFGTTTVISESTY
PSGPGVLHPKPILDPLGYGNVTVTESYTTSDTLKPSVHVHDNRPASNVVVTERVVGPISGADLHGMLEMPDLRDGSNVIVTERVIAPSSS
LPTSLTIHHPRESSNVVVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVSGAGVTGISGTTGISGGIGSSGLVGTSMGAGSGALSGA

--------------------------------------------------------------
>20577_20577_4_CTTN-DSG1_CTTN_chr11_70269101_ENST00000346329_DSG1_chr18_28906544_ENST00000257192_length(transcript)=5939nt_BP=1154nt
GGCCGGGCTAGCGCTTAGCCAGCTGCGGGCGGACCCCCGGGACTCTTGCGGGCCAAGACGCGGGAGGAGGCGGGGCAGGGGGCGGGGTCG
CGCGGGGACCCGGATGCGGCCCCGCCCCCGCCCTCGGAACCGGAAGTAGAGCCTGGTGCCTGGGAGCGGCTGGCGCGGCGGAATCCAGGG
CCGACCCGGGCCGGACCGACCCCAGGCGGCGACGGAATCAGTCCCCAATGCCTGGAAATTCCTCATTGGATTACTGTGTTTTAAACAGAA
TTTCGTGAACAGCCTTTTATCTCCAAGCGGAAAGAAAGATGTGGAAAGCTTCAGCAGGCCACGCTGTGTCCATCGCCCAGGATGACGCGG
GGGCCGATGACTGGGAGACCGACCCTGATTTTGTGAATGATGTGAGTGAGAAGGAGCAAAGATGGGGTGCCAAGACGGTGCAGGGCTCCG
GGCACCAGGAGCATATCAACATACACAAGCTGAGGGAGAATGTCTTTCAAGAGCATCAGACCCTTAAGGAGAAGGAACTTGAAACAGGAC
CAAAAGCTTCCCATGGCTATGGAGGGAAATTTGGTGTGGAACAAGACCGAATGGATAAGTCAGCTGTCGGCCACGAATATCAGTCGAAAC
TTTCCAAGCACTGCTCGCAGGTGGACTCGGTCCGTGGCTTCGGAGGCAAGTTTGGTGTCCAGATGGACAGAGTTGATCAGTCTGCTGTAG
GCTTTGAATACCAGGGGAAGACTGAGAAGCATGCCTCCCAGAAAGACTACTCCAGTGGTTTTGGCGGCAAGTATGGCGTGCAGGCCGACC
GAGTAGACAAGAGCGCGGTGGGCTTCGACTACCAGGGCAAGACGGAGAAGCACGAGTCACAGAGAGATTACTCCAAAGGTTTCGGCGGCA
AATACGGTATCGACAAGGACAAAGTGGATAAGAGCGCCGTTGGCTTTGAGTATCAAGGCAAAACGGAGAAGCACGAGTCCCAGAAAGACT
ATGTGAAAGGGTTTGGAGGAAAATTTGGTGTGCAGACAGACAGACAAGACAAATGTGCCCTTGGCTGGGATCACCAGGAGAAATTGCAGC
TGCATGAATCCCAAAAAGACTACTCCAAAGGATTCGGCGGGAAGTATGGGGTGCAGAAGGATCGGATGGATAAGGTGGTGGTAGAAGTTA
ACAGTGAATTCCGAATCCAGGTAAGAGATTATAACACTAAAAATGGCACCATCAAATGGCATTCAATCCGAAGGCAGAAACGTGAATGGA
TCAAGTTCGCAGCAGCCTGTCGTGAAGGTGAAGACAACTCAAAGAGGAACCCAATCGCCAAAATTCACTCAGATTGTGCTGCAAACCAGC
AAGTTACATACCGCATCTCTGGAGTAGGAATTGATCAGCCACCATATGGGATCTTTGTCATTAATCAGAAAACTGGTGAAATTAATATAA
CATCCATAGTTGATCGAGAGGTCACTCCTTTCTTCATTATCTACTGCCGAGCTCTGAACTCAATGGGCCAAGATTTAGAGAGGCCTCTAG
AGCTCAGAGTCAGGGTTTTGGATATAAATGACAACCCTCCAGTGTTTTCAATGGCTACATTTGCAGGACAAATAGAAGAAAATTCTAATG
CAAATACACTGGTGATGATACTCAATGCTACTGACGCAGATGAACCGAACAATTTGAACTCAAAAATAGCCTTCAAGATTATAAGACAAG
AACCTTCAGATTCACCAATGTTTATTATCAACAGAAATACTGGAGAAATTCGAACGATGAATAATTTTCTAGACAGAGAGCAATACGGCC
AGTATGCTCTTGCTGTAAGAGGCTCTGACCGAGATGGCGGGGCAGATGGCATGTCAGCGGAATGTGAGTGCAACATTAAAATCCTCGATG
TCAATGATAATATCCCTTACATGGAACAGTCTTCATATACCATAGAAATTCAAGAAAATACTCTAAATTCAAATTTGCTCGAGATTAGAG
TAATTGATTTGGATGAAGAGTTCTCAGCTAACTGGATGGCAGTAATTTTCTTTATCTCTGGAAATGAAGGAAATTGGTTTGAGATAGAAA
TGAATGAAAGAACAAATGTGGGAATTTTAAAGGTTGTTAAGCCCTTAGATTATGAAGCTATGCAGAGTCTGCAACTCAGTATTGGTGTCA
GAAATAAAGCTGAATTTCATCATTCAATTATGTCTCAATATAAACTGAAAGCATCTGCAATTTCTGTGACTGTGTTAAATGTAATTGAAG
GCCCAGTGTTTCGTCCAGGTTCAAAGACATATGTTGTAACTGGTAATATGGGATCAAATGATAAAGTGGGAGACTTTGTAGCTACTGACC
TGGACACAGGTAGACCTTCAACGACTGTTAGGTATGTAATGGGAAATAATCCAGCTGACCTGCTAGCTGTTGATTCAAGAACAGGCAAAC
TCACTTTGAAAAATAAAGTTACCAAGGAACAGTACAATATGCTCGGAGGAAAATACCAAGGAACGATTCTCTCTATAGATGATAATCTTC
AAAGAACTTGCACTGGTACAATTAATATTAACATTCAAAGTTTTGGTAATGACGACAGGACTAATACAGAGCCGAACACTAAAATTACTA
CCAATACTGGCAGACAAGAAAGTACTTCTTCCACTAACTATGATACCAGCACAACTTCTACTGACTCTAGCCAAGTATATTCTTCTGAAC
CCGGAAACGGAGCCAAAGATTTGTTATCAGACAATGTACATTTTGGTCCTGCTGGCATTGGACTCCTCATCATGGGATTCTTGGTCTTAG
GATTGGTCCCATTTTTGATGATCTGTTGTGATTGTGGAGGTGCTCCTCGTAGTGCAGCTGGCTTTGAGCCTGTTCCCGAATGTTCAGATG
GAGCAATTCATTCATGGGCAGTAGAAGGACCACAGCCTGAACCCAGGGATATAACCACTGTCATACCACAAATACCACCTGATAACGCAA
ATATAATTGAATGCATTGACAACTCAGGAGTTTATACAAATGAGTATGGTGGCAGAGAAATGCAAGATCTGGGAGGAGGAGAGAGAATGA
CAGGATTTGAACTAACAGAGGGAGTTAAAACTTCAGGAATGCCTGAGATATGTCAAGAATACTCTGGAACATTAAGAAGAAATTCTATGA
GGGAATGTAGAGAAGGAGGTCTGAATATGAATTTCATGGAAAGCTACTTCTGTCAGAAAGCATATGCTTACGCAGATGAAGATGAAGGAC
GCCCATCTAATGACTGTTTGCTCATATATGACATCGAAGGTGTAGGTTCCCCTGCTGGCTCTGTGGGTTGTTGTAGCTTCATTGGAGAAG
ACCTGGATGACAGCTTCTTGGATACCCTGGGACCTAAATTTAAGAAGTTGGCAGACATCAGCCTAGGAAAAGAATCATATCCAGACCTTG
ATCCTTCTTGGCCACCACAAAGCACTGAACCAGTTTGCCTTCCTCAGGAAACAGAGCCCGTTGTTAGTGGACACCCACCAATCTCCCCAC
ATTTCGGCACTACCACAGTAATTTCTGAGAGCACCTATCCCTCGGGACCTGGTGTACTGCATCCTAAGCCTATTCTCGATCCTCTGGGCT
ATGGTAATGTCACTGTGACCGAGTCTTACACCACCTCTGACACTCTGAAGCCCTCTGTGCACGTTCACGATAACCGACCAGCATCAAACG
TGGTAGTGACAGAGAGAGTGGTCGGCCCAATCTCTGGCGCTGATTTGCATGGAATGTTAGAGATGCCTGACTTGCGAGATGGGTCGAATG
TTATAGTGACAGAAAGGGTAATAGCACCAAGCTCTAGTCTACCCACCTCTCTGACTATCCATCATCCTAGAGAGTCTTCAAATGTGGTAG
TGACAGAAAGAGTAATCCAACCAACTTCCGGCATGATAGGTAGTCTGAGTATGCACCCCGAGTTAGCCAATGCCCACAATGTCATTGTGA
CAGAGAGGGTTGTTTCTGGTGCTGGCGTAACTGGAATTAGTGGCACCACTGGGATCAGCGGTGGCATAGGCAGCAGTGGCCTGGTTGGCA
CCAGCATGGGTGCTGGGAGCGGTGCCCTGAGTGGAGCTGGCATAAGTGGTGGTGGCATTGGCCTGAGCAGCTTGGGAGGGACAGCCAGCA
TTGGCCACATGAGGAGTTCCTCTGACCATCACTTTAACCAAACCATTGGGTCCGCCTCCCCTAGCACAGCTCGAAGTCGAATCACAAAGT
ATAGTACCGTGCAATATAGCAAGTAGTCAGGACCCCAGCTCACTTTTTCATAGTCATTGTGGTTTAGATCCAATTCCCACCACTAAAAAA
CCAACAATGTGATTTATAACGCACAACTTCGTGCTCAGGTCATCTAGGAGCAAGGTGAGAAATCACAATGAGAAAAATAAATGGAAACAC
CACTGCTAGGGGAGAGCTCTCCTTAGCATTCATAAACTTTTCTCTTATATTAGGACTAAGGAACTAAAACTTGAGGCAGAGTCTTCTTTG
TGCCTGAGTGGCCTGTAGTCCATCTCCAGCATGTAACTGGCCTTACGATGGCAATTGGCATCATTCTCCTTGCTCTGTTTTGCTTTTCCA
TATAGCTCGAGCAAAATTCAAAAAGAACTAAATATGCAATATATGTTCATATCTATGGGAAAAATCTAAAATGTGTGCCAGATGCCCTGT
TGGTTTCACAGATAACATAAATAAAAATTCAACCACAGATTTATACAAGGGTTAACCATTTTTTTTAAGTTTGACTACATAGTCAAGTCC
ACAAGCCATCAAGCACTCCTACCTTAATTATTGCACTAGAGAAAATAAATTCCAAATTAGGAAGTGTTTCCTAGGAGGAAAATTCCATTA
GAGAGTGGCAATAGGATGAGGTTTCTTCAGGGTAAACTAGCAATGCCTGAGCCTGAACCTTAATGTGGGGCCTCAGTTAAATCTCCTGTG
GAGTCAAGGATTCTTCTGATTCTAGTGTGTGTTTAGTGATAGATGTAGTCTTGACGAATATTGCTTACTGGTGAGGTTGAGGAATATCAC
ACTCGTCTTTCCCTTTACCACTGTGGTTTTGACTTAAGAAAGCAAAACTCACTAAGTTTACTTCTCGAATTGAAGCAAGTGAGGCCTGAC
ATGGTTGTCATCACTAGTGGCAAATGACCTTCCAAGTAAGCAGATGGGAACTGAATTGTGTTTTCAGGTTTTGTTTTTAGTAGGTGATAT
TCATTCGTATCCAGCTCTTTATTACATAGCTCTGAAGTTAAAATGATTTACATAGGCCGAGCTGTGGACAAAAAAAAAAGAAGCAGCAGC
TTGTAGTATGCTTAAGCTTTGGGGAATTTTTTTTTAAGGGGATCTAAAAAAATGTTTTTAGAACATGTAAAATGTTTAATGGTGAAAGTT
GGAAAAGAATTCTTCTGTAAAGTAATACCATGCTAATTATTCGCTTTTAGTAAGTAAAGTAGTGGTTGCTTTAGCAAACCTCTGCTGCCA
TTTTGCAGGAATCAACCAGGAACCTTTAGCAGAATTGACAATATGGTGTTGATAAGCATGAAATAATAATAGAAACCTATTCTGCTAGTT
TATCTCACCCTCTAATTTTTCTCACTAGCATAAATTTTAAATTCCTGATTTGATTTGTCAATAAGATCTTGGCTTATATATGCTGATTTA
TAGGTAGTGTCCAAATTATATAGTATAACATATTTTTCTAGTTTCAAAATTTAGTAATGTCCTATTTATGATATATCATTTCTGTGTGTT
TGCTATGTAGTATTACCCAATTAAAAATCTCTAAAAAGAATTAAAGCATTCTAAGAAAAAGGTAAATTTACTATTGCATGGTACAGAAAT

>20577_20577_4_CTTN-DSG1_CTTN_chr11_70269101_ENST00000346329_DSG1_chr18_28906544_ENST00000257192_length(amino acids)=1315AA_BP=282
MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRENVFQEHQTLKEKELETGPKASHGYGGKFGV
EQDRMDKSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHESQKDYSKGFG
GKYGVQKDRMDKVVVEVNSEFRIQVRDYNTKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQ
PPYGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLVMILNATDA
DEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRDGGADGMSAECECNIKILDVNDNIPYMEQSSY
TIEIQENTLNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHSIMSQ
YKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYN
MLGGKYQGTILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTSTDSSQVYSSEPGNGAKDLLSDNV
HFGPAGIGLLIMGFLVLGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSWAVEGPQPEPRDITTVIPQIPPDNANIIECIDNSGVYT
NEYGGREMQDLGGGERMTGFELTEGVKTSGMPEICQEYSGTLRRNSMRECREGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIE
GVGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLGKESYPDLDPSWPPQSTEPVCLPQETEPVVSGHPPISPHFGTTTVISESTY
PSGPGVLHPKPILDPLGYGNVTVTESYTTSDTLKPSVHVHDNRPASNVVVTERVVGPISGADLHGMLEMPDLRDGSNVIVTERVIAPSSS
LPTSLTIHHPRESSNVVVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVSGAGVTGISGTTGISGGIGSSGLVGTSMGAGSGALSGA

--------------------------------------------------------------
>20577_20577_5_CTTN-DSG1_CTTN_chr11_70269101_ENST00000376561_DSG1_chr18_28906543_ENST00000257192_length(transcript)=5802nt_BP=1017nt
AGAGCCTGGTGCCTGGGAGCGGCTGGCGCGGCGGAATCCAGGGCCGACCCGGGCCGGACCGACCCCAGGCGGCGACGGAATCAGTCCCCA
ATGCCTGGAAATTCCTCATTGGATTACTGTGTTTTAAACAGAATTTCGTGAACAGCCTTTTATCTCCAAGCGGAAAGAAAGATGTGGAAA
GCTTCAGCAGGCCACGCTGTGTCCATCGCCCAGGATGACGCGGGGGCCGATGACTGGGAGACCGACCCTGATTTTGTGAATGATGTGAGT
GAGAAGGAGCAAAGATGGGGTGCCAAGACGGTGCAGGGCTCCGGGCACCAGGAGCATATCAACATACACAAGCTGAGGGAGAATGTCTTT
CAAGAGCATCAGACCCTTAAGGAGAAGGAACTTGAAACAGGACCAAAAGCTTCCCATGGCTATGGAGGGAAATTTGGTGTGGAACAAGAC
CGAATGGATAAGTCAGCTGTCGGCCACGAATATCAGTCGAAACTTTCCAAGCACTGCTCGCAGGTGGACTCGGTCCGTGGCTTCGGAGGC
AAGTTTGGTGTCCAGATGGACAGAGTTGATCAGTCTGCTGTAGGCTTTGAATACCAGGGGAAGACTGAGAAGCATGCCTCCCAGAAAGAC
TACTCCAGTGGTTTTGGCGGCAAGTATGGCGTGCAGGCCGACCGAGTAGACAAGAGCGCGGTGGGCTTCGACTACCAGGGCAAGACGGAG
AAGCACGAGTCACAGAGAGATTACTCCAAAGGTTTCGGCGGCAAATACGGTATCGACAAGGACAAAGTGGATAAGAGCGCCGTTGGCTTT
GAGTATCAAGGCAAAACGGAGAAGCACGAGTCCCAGAAAGACTATGTGAAAGGGTTTGGAGGAAAATTTGGTGTGCAGACAGACAGACAA
GACAAATGTGCCCTTGGCTGGGATCACCAGGAGAAATTGCAGCTGCATGAATCCCAAAAAGACTACTCCAAAGGATTCGGCGGGAAGTAT
GGGGTGCAGAAGGATCGGATGGATAAGGTGGTGGTAGAAGTTAACAGTGAATTCCGAATCCAGGTAAGAGATTATAACACTAAAAATGGC
ACCATCAAATGGCATTCAATCCGAAGGCAGAAACGTGAATGGATCAAGTTCGCAGCAGCCTGTCGTGAAGGTGAAGACAACTCAAAGAGG
AACCCAATCGCCAAAATTCACTCAGATTGTGCTGCAAACCAGCAAGTTACATACCGCATCTCTGGAGTAGGAATTGATCAGCCACCATAT
GGGATCTTTGTCATTAATCAGAAAACTGGTGAAATTAATATAACATCCATAGTTGATCGAGAGGTCACTCCTTTCTTCATTATCTACTGC
CGAGCTCTGAACTCAATGGGCCAAGATTTAGAGAGGCCTCTAGAGCTCAGAGTCAGGGTTTTGGATATAAATGACAACCCTCCAGTGTTT
TCAATGGCTACATTTGCAGGACAAATAGAAGAAAATTCTAATGCAAATACACTGGTGATGATACTCAATGCTACTGACGCAGATGAACCG
AACAATTTGAACTCAAAAATAGCCTTCAAGATTATAAGACAAGAACCTTCAGATTCACCAATGTTTATTATCAACAGAAATACTGGAGAA
ATTCGAACGATGAATAATTTTCTAGACAGAGAGCAATACGGCCAGTATGCTCTTGCTGTAAGAGGCTCTGACCGAGATGGCGGGGCAGAT
GGCATGTCAGCGGAATGTGAGTGCAACATTAAAATCCTCGATGTCAATGATAATATCCCTTACATGGAACAGTCTTCATATACCATAGAA
ATTCAAGAAAATACTCTAAATTCAAATTTGCTCGAGATTAGAGTAATTGATTTGGATGAAGAGTTCTCAGCTAACTGGATGGCAGTAATT
TTCTTTATCTCTGGAAATGAAGGAAATTGGTTTGAGATAGAAATGAATGAAAGAACAAATGTGGGAATTTTAAAGGTTGTTAAGCCCTTA
GATTATGAAGCTATGCAGAGTCTGCAACTCAGTATTGGTGTCAGAAATAAAGCTGAATTTCATCATTCAATTATGTCTCAATATAAACTG
AAAGCATCTGCAATTTCTGTGACTGTGTTAAATGTAATTGAAGGCCCAGTGTTTCGTCCAGGTTCAAAGACATATGTTGTAACTGGTAAT
ATGGGATCAAATGATAAAGTGGGAGACTTTGTAGCTACTGACCTGGACACAGGTAGACCTTCAACGACTGTTAGGTATGTAATGGGAAAT
AATCCAGCTGACCTGCTAGCTGTTGATTCAAGAACAGGCAAACTCACTTTGAAAAATAAAGTTACCAAGGAACAGTACAATATGCTCGGA
GGAAAATACCAAGGAACGATTCTCTCTATAGATGATAATCTTCAAAGAACTTGCACTGGTACAATTAATATTAACATTCAAAGTTTTGGT
AATGACGACAGGACTAATACAGAGCCGAACACTAAAATTACTACCAATACTGGCAGACAAGAAAGTACTTCTTCCACTAACTATGATACC
AGCACAACTTCTACTGACTCTAGCCAAGTATATTCTTCTGAACCCGGAAACGGAGCCAAAGATTTGTTATCAGACAATGTACATTTTGGT
CCTGCTGGCATTGGACTCCTCATCATGGGATTCTTGGTCTTAGGATTGGTCCCATTTTTGATGATCTGTTGTGATTGTGGAGGTGCTCCT
CGTAGTGCAGCTGGCTTTGAGCCTGTTCCCGAATGTTCAGATGGAGCAATTCATTCATGGGCAGTAGAAGGACCACAGCCTGAACCCAGG
GATATAACCACTGTCATACCACAAATACCACCTGATAACGCAAATATAATTGAATGCATTGACAACTCAGGAGTTTATACAAATGAGTAT
GGTGGCAGAGAAATGCAAGATCTGGGAGGAGGAGAGAGAATGACAGGATTTGAACTAACAGAGGGAGTTAAAACTTCAGGAATGCCTGAG
ATATGTCAAGAATACTCTGGAACATTAAGAAGAAATTCTATGAGGGAATGTAGAGAAGGAGGTCTGAATATGAATTTCATGGAAAGCTAC
TTCTGTCAGAAAGCATATGCTTACGCAGATGAAGATGAAGGACGCCCATCTAATGACTGTTTGCTCATATATGACATCGAAGGTGTAGGT
TCCCCTGCTGGCTCTGTGGGTTGTTGTAGCTTCATTGGAGAAGACCTGGATGACAGCTTCTTGGATACCCTGGGACCTAAATTTAAGAAG
TTGGCAGACATCAGCCTAGGAAAAGAATCATATCCAGACCTTGATCCTTCTTGGCCACCACAAAGCACTGAACCAGTTTGCCTTCCTCAG
GAAACAGAGCCCGTTGTTAGTGGACACCCACCAATCTCCCCACATTTCGGCACTACCACAGTAATTTCTGAGAGCACCTATCCCTCGGGA
CCTGGTGTACTGCATCCTAAGCCTATTCTCGATCCTCTGGGCTATGGTAATGTCACTGTGACCGAGTCTTACACCACCTCTGACACTCTG
AAGCCCTCTGTGCACGTTCACGATAACCGACCAGCATCAAACGTGGTAGTGACAGAGAGAGTGGTCGGCCCAATCTCTGGCGCTGATTTG
CATGGAATGTTAGAGATGCCTGACTTGCGAGATGGGTCGAATGTTATAGTGACAGAAAGGGTAATAGCACCAAGCTCTAGTCTACCCACC
TCTCTGACTATCCATCATCCTAGAGAGTCTTCAAATGTGGTAGTGACAGAAAGAGTAATCCAACCAACTTCCGGCATGATAGGTAGTCTG
AGTATGCACCCCGAGTTAGCCAATGCCCACAATGTCATTGTGACAGAGAGGGTTGTTTCTGGTGCTGGCGTAACTGGAATTAGTGGCACC
ACTGGGATCAGCGGTGGCATAGGCAGCAGTGGCCTGGTTGGCACCAGCATGGGTGCTGGGAGCGGTGCCCTGAGTGGAGCTGGCATAAGT
GGTGGTGGCATTGGCCTGAGCAGCTTGGGAGGGACAGCCAGCATTGGCCACATGAGGAGTTCCTCTGACCATCACTTTAACCAAACCATT
GGGTCCGCCTCCCCTAGCACAGCTCGAAGTCGAATCACAAAGTATAGTACCGTGCAATATAGCAAGTAGTCAGGACCCCAGCTCACTTTT
TCATAGTCATTGTGGTTTAGATCCAATTCCCACCACTAAAAAACCAACAATGTGATTTATAACGCACAACTTCGTGCTCAGGTCATCTAG
GAGCAAGGTGAGAAATCACAATGAGAAAAATAAATGGAAACACCACTGCTAGGGGAGAGCTCTCCTTAGCATTCATAAACTTTTCTCTTA
TATTAGGACTAAGGAACTAAAACTTGAGGCAGAGTCTTCTTTGTGCCTGAGTGGCCTGTAGTCCATCTCCAGCATGTAACTGGCCTTACG
ATGGCAATTGGCATCATTCTCCTTGCTCTGTTTTGCTTTTCCATATAGCTCGAGCAAAATTCAAAAAGAACTAAATATGCAATATATGTT
CATATCTATGGGAAAAATCTAAAATGTGTGCCAGATGCCCTGTTGGTTTCACAGATAACATAAATAAAAATTCAACCACAGATTTATACA
AGGGTTAACCATTTTTTTTAAGTTTGACTACATAGTCAAGTCCACAAGCCATCAAGCACTCCTACCTTAATTATTGCACTAGAGAAAATA
AATTCCAAATTAGGAAGTGTTTCCTAGGAGGAAAATTCCATTAGAGAGTGGCAATAGGATGAGGTTTCTTCAGGGTAAACTAGCAATGCC
TGAGCCTGAACCTTAATGTGGGGCCTCAGTTAAATCTCCTGTGGAGTCAAGGATTCTTCTGATTCTAGTGTGTGTTTAGTGATAGATGTA
GTCTTGACGAATATTGCTTACTGGTGAGGTTGAGGAATATCACACTCGTCTTTCCCTTTACCACTGTGGTTTTGACTTAAGAAAGCAAAA
CTCACTAAGTTTACTTCTCGAATTGAAGCAAGTGAGGCCTGACATGGTTGTCATCACTAGTGGCAAATGACCTTCCAAGTAAGCAGATGG
GAACTGAATTGTGTTTTCAGGTTTTGTTTTTAGTAGGTGATATTCATTCGTATCCAGCTCTTTATTACATAGCTCTGAAGTTAAAATGAT
TTACATAGGCCGAGCTGTGGACAAAAAAAAAAGAAGCAGCAGCTTGTAGTATGCTTAAGCTTTGGGGAATTTTTTTTTAAGGGGATCTAA
AAAAATGTTTTTAGAACATGTAAAATGTTTAATGGTGAAAGTTGGAAAAGAATTCTTCTGTAAAGTAATACCATGCTAATTATTCGCTTT
TAGTAAGTAAAGTAGTGGTTGCTTTAGCAAACCTCTGCTGCCATTTTGCAGGAATCAACCAGGAACCTTTAGCAGAATTGACAATATGGT
GTTGATAAGCATGAAATAATAATAGAAACCTATTCTGCTAGTTTATCTCACCCTCTAATTTTTCTCACTAGCATAAATTTTAAATTCCTG
ATTTGATTTGTCAATAAGATCTTGGCTTATATATGCTGATTTATAGGTAGTGTCCAAATTATATAGTATAACATATTTTTCTAGTTTCAA
AATTTAGTAATGTCCTATTTATGATATATCATTTCTGTGTGTTTGCTATGTAGTATTACCCAATTAAAAATCTCTAAAAAGAATTAAAGC
ATTCTAAGAAAAAGGTAAATTTACTATTGCATGGTACAGAAATTTTTTCTTTCTTAAATACAATGTTACTATAAGCTCACTAAAATGAAA

>20577_20577_5_CTTN-DSG1_CTTN_chr11_70269101_ENST00000376561_DSG1_chr18_28906543_ENST00000257192_length(amino acids)=1315AA_BP=282
MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRENVFQEHQTLKEKELETGPKASHGYGGKFGV
EQDRMDKSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHESQKDYSKGFG
GKYGVQKDRMDKVVVEVNSEFRIQVRDYNTKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQ
PPYGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLVMILNATDA
DEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRDGGADGMSAECECNIKILDVNDNIPYMEQSSY
TIEIQENTLNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHSIMSQ
YKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYN
MLGGKYQGTILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTSTDSSQVYSSEPGNGAKDLLSDNV
HFGPAGIGLLIMGFLVLGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSWAVEGPQPEPRDITTVIPQIPPDNANIIECIDNSGVYT
NEYGGREMQDLGGGERMTGFELTEGVKTSGMPEICQEYSGTLRRNSMRECREGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIE
GVGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLGKESYPDLDPSWPPQSTEPVCLPQETEPVVSGHPPISPHFGTTTVISESTY
PSGPGVLHPKPILDPLGYGNVTVTESYTTSDTLKPSVHVHDNRPASNVVVTERVVGPISGADLHGMLEMPDLRDGSNVIVTERVIAPSSS
LPTSLTIHHPRESSNVVVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVSGAGVTGISGTTGISGGIGSSGLVGTSMGAGSGALSGA

--------------------------------------------------------------
>20577_20577_6_CTTN-DSG1_CTTN_chr11_70269101_ENST00000376561_DSG1_chr18_28906544_ENST00000257192_length(transcript)=5802nt_BP=1017nt
AGAGCCTGGTGCCTGGGAGCGGCTGGCGCGGCGGAATCCAGGGCCGACCCGGGCCGGACCGACCCCAGGCGGCGACGGAATCAGTCCCCA
ATGCCTGGAAATTCCTCATTGGATTACTGTGTTTTAAACAGAATTTCGTGAACAGCCTTTTATCTCCAAGCGGAAAGAAAGATGTGGAAA
GCTTCAGCAGGCCACGCTGTGTCCATCGCCCAGGATGACGCGGGGGCCGATGACTGGGAGACCGACCCTGATTTTGTGAATGATGTGAGT
GAGAAGGAGCAAAGATGGGGTGCCAAGACGGTGCAGGGCTCCGGGCACCAGGAGCATATCAACATACACAAGCTGAGGGAGAATGTCTTT
CAAGAGCATCAGACCCTTAAGGAGAAGGAACTTGAAACAGGACCAAAAGCTTCCCATGGCTATGGAGGGAAATTTGGTGTGGAACAAGAC
CGAATGGATAAGTCAGCTGTCGGCCACGAATATCAGTCGAAACTTTCCAAGCACTGCTCGCAGGTGGACTCGGTCCGTGGCTTCGGAGGC
AAGTTTGGTGTCCAGATGGACAGAGTTGATCAGTCTGCTGTAGGCTTTGAATACCAGGGGAAGACTGAGAAGCATGCCTCCCAGAAAGAC
TACTCCAGTGGTTTTGGCGGCAAGTATGGCGTGCAGGCCGACCGAGTAGACAAGAGCGCGGTGGGCTTCGACTACCAGGGCAAGACGGAG
AAGCACGAGTCACAGAGAGATTACTCCAAAGGTTTCGGCGGCAAATACGGTATCGACAAGGACAAAGTGGATAAGAGCGCCGTTGGCTTT
GAGTATCAAGGCAAAACGGAGAAGCACGAGTCCCAGAAAGACTATGTGAAAGGGTTTGGAGGAAAATTTGGTGTGCAGACAGACAGACAA
GACAAATGTGCCCTTGGCTGGGATCACCAGGAGAAATTGCAGCTGCATGAATCCCAAAAAGACTACTCCAAAGGATTCGGCGGGAAGTAT
GGGGTGCAGAAGGATCGGATGGATAAGGTGGTGGTAGAAGTTAACAGTGAATTCCGAATCCAGGTAAGAGATTATAACACTAAAAATGGC
ACCATCAAATGGCATTCAATCCGAAGGCAGAAACGTGAATGGATCAAGTTCGCAGCAGCCTGTCGTGAAGGTGAAGACAACTCAAAGAGG
AACCCAATCGCCAAAATTCACTCAGATTGTGCTGCAAACCAGCAAGTTACATACCGCATCTCTGGAGTAGGAATTGATCAGCCACCATAT
GGGATCTTTGTCATTAATCAGAAAACTGGTGAAATTAATATAACATCCATAGTTGATCGAGAGGTCACTCCTTTCTTCATTATCTACTGC
CGAGCTCTGAACTCAATGGGCCAAGATTTAGAGAGGCCTCTAGAGCTCAGAGTCAGGGTTTTGGATATAAATGACAACCCTCCAGTGTTT
TCAATGGCTACATTTGCAGGACAAATAGAAGAAAATTCTAATGCAAATACACTGGTGATGATACTCAATGCTACTGACGCAGATGAACCG
AACAATTTGAACTCAAAAATAGCCTTCAAGATTATAAGACAAGAACCTTCAGATTCACCAATGTTTATTATCAACAGAAATACTGGAGAA
ATTCGAACGATGAATAATTTTCTAGACAGAGAGCAATACGGCCAGTATGCTCTTGCTGTAAGAGGCTCTGACCGAGATGGCGGGGCAGAT
GGCATGTCAGCGGAATGTGAGTGCAACATTAAAATCCTCGATGTCAATGATAATATCCCTTACATGGAACAGTCTTCATATACCATAGAA
ATTCAAGAAAATACTCTAAATTCAAATTTGCTCGAGATTAGAGTAATTGATTTGGATGAAGAGTTCTCAGCTAACTGGATGGCAGTAATT
TTCTTTATCTCTGGAAATGAAGGAAATTGGTTTGAGATAGAAATGAATGAAAGAACAAATGTGGGAATTTTAAAGGTTGTTAAGCCCTTA
GATTATGAAGCTATGCAGAGTCTGCAACTCAGTATTGGTGTCAGAAATAAAGCTGAATTTCATCATTCAATTATGTCTCAATATAAACTG
AAAGCATCTGCAATTTCTGTGACTGTGTTAAATGTAATTGAAGGCCCAGTGTTTCGTCCAGGTTCAAAGACATATGTTGTAACTGGTAAT
ATGGGATCAAATGATAAAGTGGGAGACTTTGTAGCTACTGACCTGGACACAGGTAGACCTTCAACGACTGTTAGGTATGTAATGGGAAAT
AATCCAGCTGACCTGCTAGCTGTTGATTCAAGAACAGGCAAACTCACTTTGAAAAATAAAGTTACCAAGGAACAGTACAATATGCTCGGA
GGAAAATACCAAGGAACGATTCTCTCTATAGATGATAATCTTCAAAGAACTTGCACTGGTACAATTAATATTAACATTCAAAGTTTTGGT
AATGACGACAGGACTAATACAGAGCCGAACACTAAAATTACTACCAATACTGGCAGACAAGAAAGTACTTCTTCCACTAACTATGATACC
AGCACAACTTCTACTGACTCTAGCCAAGTATATTCTTCTGAACCCGGAAACGGAGCCAAAGATTTGTTATCAGACAATGTACATTTTGGT
CCTGCTGGCATTGGACTCCTCATCATGGGATTCTTGGTCTTAGGATTGGTCCCATTTTTGATGATCTGTTGTGATTGTGGAGGTGCTCCT
CGTAGTGCAGCTGGCTTTGAGCCTGTTCCCGAATGTTCAGATGGAGCAATTCATTCATGGGCAGTAGAAGGACCACAGCCTGAACCCAGG
GATATAACCACTGTCATACCACAAATACCACCTGATAACGCAAATATAATTGAATGCATTGACAACTCAGGAGTTTATACAAATGAGTAT
GGTGGCAGAGAAATGCAAGATCTGGGAGGAGGAGAGAGAATGACAGGATTTGAACTAACAGAGGGAGTTAAAACTTCAGGAATGCCTGAG
ATATGTCAAGAATACTCTGGAACATTAAGAAGAAATTCTATGAGGGAATGTAGAGAAGGAGGTCTGAATATGAATTTCATGGAAAGCTAC
TTCTGTCAGAAAGCATATGCTTACGCAGATGAAGATGAAGGACGCCCATCTAATGACTGTTTGCTCATATATGACATCGAAGGTGTAGGT
TCCCCTGCTGGCTCTGTGGGTTGTTGTAGCTTCATTGGAGAAGACCTGGATGACAGCTTCTTGGATACCCTGGGACCTAAATTTAAGAAG
TTGGCAGACATCAGCCTAGGAAAAGAATCATATCCAGACCTTGATCCTTCTTGGCCACCACAAAGCACTGAACCAGTTTGCCTTCCTCAG
GAAACAGAGCCCGTTGTTAGTGGACACCCACCAATCTCCCCACATTTCGGCACTACCACAGTAATTTCTGAGAGCACCTATCCCTCGGGA
CCTGGTGTACTGCATCCTAAGCCTATTCTCGATCCTCTGGGCTATGGTAATGTCACTGTGACCGAGTCTTACACCACCTCTGACACTCTG
AAGCCCTCTGTGCACGTTCACGATAACCGACCAGCATCAAACGTGGTAGTGACAGAGAGAGTGGTCGGCCCAATCTCTGGCGCTGATTTG
CATGGAATGTTAGAGATGCCTGACTTGCGAGATGGGTCGAATGTTATAGTGACAGAAAGGGTAATAGCACCAAGCTCTAGTCTACCCACC
TCTCTGACTATCCATCATCCTAGAGAGTCTTCAAATGTGGTAGTGACAGAAAGAGTAATCCAACCAACTTCCGGCATGATAGGTAGTCTG
AGTATGCACCCCGAGTTAGCCAATGCCCACAATGTCATTGTGACAGAGAGGGTTGTTTCTGGTGCTGGCGTAACTGGAATTAGTGGCACC
ACTGGGATCAGCGGTGGCATAGGCAGCAGTGGCCTGGTTGGCACCAGCATGGGTGCTGGGAGCGGTGCCCTGAGTGGAGCTGGCATAAGT
GGTGGTGGCATTGGCCTGAGCAGCTTGGGAGGGACAGCCAGCATTGGCCACATGAGGAGTTCCTCTGACCATCACTTTAACCAAACCATT
GGGTCCGCCTCCCCTAGCACAGCTCGAAGTCGAATCACAAAGTATAGTACCGTGCAATATAGCAAGTAGTCAGGACCCCAGCTCACTTTT
TCATAGTCATTGTGGTTTAGATCCAATTCCCACCACTAAAAAACCAACAATGTGATTTATAACGCACAACTTCGTGCTCAGGTCATCTAG
GAGCAAGGTGAGAAATCACAATGAGAAAAATAAATGGAAACACCACTGCTAGGGGAGAGCTCTCCTTAGCATTCATAAACTTTTCTCTTA
TATTAGGACTAAGGAACTAAAACTTGAGGCAGAGTCTTCTTTGTGCCTGAGTGGCCTGTAGTCCATCTCCAGCATGTAACTGGCCTTACG
ATGGCAATTGGCATCATTCTCCTTGCTCTGTTTTGCTTTTCCATATAGCTCGAGCAAAATTCAAAAAGAACTAAATATGCAATATATGTT
CATATCTATGGGAAAAATCTAAAATGTGTGCCAGATGCCCTGTTGGTTTCACAGATAACATAAATAAAAATTCAACCACAGATTTATACA
AGGGTTAACCATTTTTTTTAAGTTTGACTACATAGTCAAGTCCACAAGCCATCAAGCACTCCTACCTTAATTATTGCACTAGAGAAAATA
AATTCCAAATTAGGAAGTGTTTCCTAGGAGGAAAATTCCATTAGAGAGTGGCAATAGGATGAGGTTTCTTCAGGGTAAACTAGCAATGCC
TGAGCCTGAACCTTAATGTGGGGCCTCAGTTAAATCTCCTGTGGAGTCAAGGATTCTTCTGATTCTAGTGTGTGTTTAGTGATAGATGTA
GTCTTGACGAATATTGCTTACTGGTGAGGTTGAGGAATATCACACTCGTCTTTCCCTTTACCACTGTGGTTTTGACTTAAGAAAGCAAAA
CTCACTAAGTTTACTTCTCGAATTGAAGCAAGTGAGGCCTGACATGGTTGTCATCACTAGTGGCAAATGACCTTCCAAGTAAGCAGATGG
GAACTGAATTGTGTTTTCAGGTTTTGTTTTTAGTAGGTGATATTCATTCGTATCCAGCTCTTTATTACATAGCTCTGAAGTTAAAATGAT
TTACATAGGCCGAGCTGTGGACAAAAAAAAAAGAAGCAGCAGCTTGTAGTATGCTTAAGCTTTGGGGAATTTTTTTTTAAGGGGATCTAA
AAAAATGTTTTTAGAACATGTAAAATGTTTAATGGTGAAAGTTGGAAAAGAATTCTTCTGTAAAGTAATACCATGCTAATTATTCGCTTT
TAGTAAGTAAAGTAGTGGTTGCTTTAGCAAACCTCTGCTGCCATTTTGCAGGAATCAACCAGGAACCTTTAGCAGAATTGACAATATGGT
GTTGATAAGCATGAAATAATAATAGAAACCTATTCTGCTAGTTTATCTCACCCTCTAATTTTTCTCACTAGCATAAATTTTAAATTCCTG
ATTTGATTTGTCAATAAGATCTTGGCTTATATATGCTGATTTATAGGTAGTGTCCAAATTATATAGTATAACATATTTTTCTAGTTTCAA
AATTTAGTAATGTCCTATTTATGATATATCATTTCTGTGTGTTTGCTATGTAGTATTACCCAATTAAAAATCTCTAAAAAGAATTAAAGC
ATTCTAAGAAAAAGGTAAATTTACTATTGCATGGTACAGAAATTTTTTCTTTCTTAAATACAATGTTACTATAAGCTCACTAAAATGAAA

>20577_20577_6_CTTN-DSG1_CTTN_chr11_70269101_ENST00000376561_DSG1_chr18_28906544_ENST00000257192_length(amino acids)=1315AA_BP=282
MWKASAGHAVSIAQDDAGADDWETDPDFVNDVSEKEQRWGAKTVQGSGHQEHINIHKLRENVFQEHQTLKEKELETGPKASHGYGGKFGV
EQDRMDKSAVGHEYQSKLSKHCSQVDSVRGFGGKFGVQMDRVDQSAVGFEYQGKTEKHASQKDYSSGFGGKYGVQADRVDKSAVGFDYQG
KTEKHESQRDYSKGFGGKYGIDKDKVDKSAVGFEYQGKTEKHESQKDYVKGFGGKFGVQTDRQDKCALGWDHQEKLQLHESQKDYSKGFG
GKYGVQKDRMDKVVVEVNSEFRIQVRDYNTKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQ
PPYGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLVMILNATDA
DEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRDGGADGMSAECECNIKILDVNDNIPYMEQSSY
TIEIQENTLNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHSIMSQ
YKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYN
MLGGKYQGTILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTSTDSSQVYSSEPGNGAKDLLSDNV
HFGPAGIGLLIMGFLVLGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSWAVEGPQPEPRDITTVIPQIPPDNANIIECIDNSGVYT
NEYGGREMQDLGGGERMTGFELTEGVKTSGMPEICQEYSGTLRRNSMRECREGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIE
GVGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLGKESYPDLDPSWPPQSTEPVCLPQETEPVVSGHPPISPHFGTTTVISESTY
PSGPGVLHPKPILDPLGYGNVTVTESYTTSDTLKPSVHVHDNRPASNVVVTERVVGPISGADLHGMLEMPDLRDGSNVIVTERVIAPSSS
LPTSLTIHHPRESSNVVVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVSGAGVTGISGTTGISGGIGSSGLVGTSMGAGSGALSGA

--------------------------------------------------------------
>20577_20577_7_CTTN-DSG1_CTTN_chr11_70269101_ENST00000538675_DSG1_chr18_28906543_ENST00000257192_length(transcript)=4942nt_BP=157nt
GCATGAATCCCAAAAAGCAAGAGAACAAACTGCGATTGAGCCTCTTTTTAGCGCTCAGTAGAGCAGGCGCACAGGAAGCAGATGAGAATA
AGCCCGTGCTGACTACTCCAAAGGATTCGGCGGGAAGTATGGGGTGCAGAAGGATCGGATGGATAAGGTGGTGGTAGAAGTTAACAGTGA
ATTCCGAATCCAGGTAAGAGATTATAACACTAAAAATGGCACCATCAAATGGCATTCAATCCGAAGGCAGAAACGTGAATGGATCAAGTT
CGCAGCAGCCTGTCGTGAAGGTGAAGACAACTCAAAGAGGAACCCAATCGCCAAAATTCACTCAGATTGTGCTGCAAACCAGCAAGTTAC
ATACCGCATCTCTGGAGTAGGAATTGATCAGCCACCATATGGGATCTTTGTCATTAATCAGAAAACTGGTGAAATTAATATAACATCCAT
AGTTGATCGAGAGGTCACTCCTTTCTTCATTATCTACTGCCGAGCTCTGAACTCAATGGGCCAAGATTTAGAGAGGCCTCTAGAGCTCAG
AGTCAGGGTTTTGGATATAAATGACAACCCTCCAGTGTTTTCAATGGCTACATTTGCAGGACAAATAGAAGAAAATTCTAATGCAAATAC
ACTGGTGATGATACTCAATGCTACTGACGCAGATGAACCGAACAATTTGAACTCAAAAATAGCCTTCAAGATTATAAGACAAGAACCTTC
AGATTCACCAATGTTTATTATCAACAGAAATACTGGAGAAATTCGAACGATGAATAATTTTCTAGACAGAGAGCAATACGGCCAGTATGC
TCTTGCTGTAAGAGGCTCTGACCGAGATGGCGGGGCAGATGGCATGTCAGCGGAATGTGAGTGCAACATTAAAATCCTCGATGTCAATGA
TAATATCCCTTACATGGAACAGTCTTCATATACCATAGAAATTCAAGAAAATACTCTAAATTCAAATTTGCTCGAGATTAGAGTAATTGA
TTTGGATGAAGAGTTCTCAGCTAACTGGATGGCAGTAATTTTCTTTATCTCTGGAAATGAAGGAAATTGGTTTGAGATAGAAATGAATGA
AAGAACAAATGTGGGAATTTTAAAGGTTGTTAAGCCCTTAGATTATGAAGCTATGCAGAGTCTGCAACTCAGTATTGGTGTCAGAAATAA
AGCTGAATTTCATCATTCAATTATGTCTCAATATAAACTGAAAGCATCTGCAATTTCTGTGACTGTGTTAAATGTAATTGAAGGCCCAGT
GTTTCGTCCAGGTTCAAAGACATATGTTGTAACTGGTAATATGGGATCAAATGATAAAGTGGGAGACTTTGTAGCTACTGACCTGGACAC
AGGTAGACCTTCAACGACTGTTAGGTATGTAATGGGAAATAATCCAGCTGACCTGCTAGCTGTTGATTCAAGAACAGGCAAACTCACTTT
GAAAAATAAAGTTACCAAGGAACAGTACAATATGCTCGGAGGAAAATACCAAGGAACGATTCTCTCTATAGATGATAATCTTCAAAGAAC
TTGCACTGGTACAATTAATATTAACATTCAAAGTTTTGGTAATGACGACAGGACTAATACAGAGCCGAACACTAAAATTACTACCAATAC
TGGCAGACAAGAAAGTACTTCTTCCACTAACTATGATACCAGCACAACTTCTACTGACTCTAGCCAAGTATATTCTTCTGAACCCGGAAA
CGGAGCCAAAGATTTGTTATCAGACAATGTACATTTTGGTCCTGCTGGCATTGGACTCCTCATCATGGGATTCTTGGTCTTAGGATTGGT
CCCATTTTTGATGATCTGTTGTGATTGTGGAGGTGCTCCTCGTAGTGCAGCTGGCTTTGAGCCTGTTCCCGAATGTTCAGATGGAGCAAT
TCATTCATGGGCAGTAGAAGGACCACAGCCTGAACCCAGGGATATAACCACTGTCATACCACAAATACCACCTGATAACGCAAATATAAT
TGAATGCATTGACAACTCAGGAGTTTATACAAATGAGTATGGTGGCAGAGAAATGCAAGATCTGGGAGGAGGAGAGAGAATGACAGGATT
TGAACTAACAGAGGGAGTTAAAACTTCAGGAATGCCTGAGATATGTCAAGAATACTCTGGAACATTAAGAAGAAATTCTATGAGGGAATG
TAGAGAAGGAGGTCTGAATATGAATTTCATGGAAAGCTACTTCTGTCAGAAAGCATATGCTTACGCAGATGAAGATGAAGGACGCCCATC
TAATGACTGTTTGCTCATATATGACATCGAAGGTGTAGGTTCCCCTGCTGGCTCTGTGGGTTGTTGTAGCTTCATTGGAGAAGACCTGGA
TGACAGCTTCTTGGATACCCTGGGACCTAAATTTAAGAAGTTGGCAGACATCAGCCTAGGAAAAGAATCATATCCAGACCTTGATCCTTC
TTGGCCACCACAAAGCACTGAACCAGTTTGCCTTCCTCAGGAAACAGAGCCCGTTGTTAGTGGACACCCACCAATCTCCCCACATTTCGG
CACTACCACAGTAATTTCTGAGAGCACCTATCCCTCGGGACCTGGTGTACTGCATCCTAAGCCTATTCTCGATCCTCTGGGCTATGGTAA
TGTCACTGTGACCGAGTCTTACACCACCTCTGACACTCTGAAGCCCTCTGTGCACGTTCACGATAACCGACCAGCATCAAACGTGGTAGT
GACAGAGAGAGTGGTCGGCCCAATCTCTGGCGCTGATTTGCATGGAATGTTAGAGATGCCTGACTTGCGAGATGGGTCGAATGTTATAGT
GACAGAAAGGGTAATAGCACCAAGCTCTAGTCTACCCACCTCTCTGACTATCCATCATCCTAGAGAGTCTTCAAATGTGGTAGTGACAGA
AAGAGTAATCCAACCAACTTCCGGCATGATAGGTAGTCTGAGTATGCACCCCGAGTTAGCCAATGCCCACAATGTCATTGTGACAGAGAG
GGTTGTTTCTGGTGCTGGCGTAACTGGAATTAGTGGCACCACTGGGATCAGCGGTGGCATAGGCAGCAGTGGCCTGGTTGGCACCAGCAT
GGGTGCTGGGAGCGGTGCCCTGAGTGGAGCTGGCATAAGTGGTGGTGGCATTGGCCTGAGCAGCTTGGGAGGGACAGCCAGCATTGGCCA
CATGAGGAGTTCCTCTGACCATCACTTTAACCAAACCATTGGGTCCGCCTCCCCTAGCACAGCTCGAAGTCGAATCACAAAGTATAGTAC
CGTGCAATATAGCAAGTAGTCAGGACCCCAGCTCACTTTTTCATAGTCATTGTGGTTTAGATCCAATTCCCACCACTAAAAAACCAACAA
TGTGATTTATAACGCACAACTTCGTGCTCAGGTCATCTAGGAGCAAGGTGAGAAATCACAATGAGAAAAATAAATGGAAACACCACTGCT
AGGGGAGAGCTCTCCTTAGCATTCATAAACTTTTCTCTTATATTAGGACTAAGGAACTAAAACTTGAGGCAGAGTCTTCTTTGTGCCTGA
GTGGCCTGTAGTCCATCTCCAGCATGTAACTGGCCTTACGATGGCAATTGGCATCATTCTCCTTGCTCTGTTTTGCTTTTCCATATAGCT
CGAGCAAAATTCAAAAAGAACTAAATATGCAATATATGTTCATATCTATGGGAAAAATCTAAAATGTGTGCCAGATGCCCTGTTGGTTTC
ACAGATAACATAAATAAAAATTCAACCACAGATTTATACAAGGGTTAACCATTTTTTTTAAGTTTGACTACATAGTCAAGTCCACAAGCC
ATCAAGCACTCCTACCTTAATTATTGCACTAGAGAAAATAAATTCCAAATTAGGAAGTGTTTCCTAGGAGGAAAATTCCATTAGAGAGTG
GCAATAGGATGAGGTTTCTTCAGGGTAAACTAGCAATGCCTGAGCCTGAACCTTAATGTGGGGCCTCAGTTAAATCTCCTGTGGAGTCAA
GGATTCTTCTGATTCTAGTGTGTGTTTAGTGATAGATGTAGTCTTGACGAATATTGCTTACTGGTGAGGTTGAGGAATATCACACTCGTC
TTTCCCTTTACCACTGTGGTTTTGACTTAAGAAAGCAAAACTCACTAAGTTTACTTCTCGAATTGAAGCAAGTGAGGCCTGACATGGTTG
TCATCACTAGTGGCAAATGACCTTCCAAGTAAGCAGATGGGAACTGAATTGTGTTTTCAGGTTTTGTTTTTAGTAGGTGATATTCATTCG
TATCCAGCTCTTTATTACATAGCTCTGAAGTTAAAATGATTTACATAGGCCGAGCTGTGGACAAAAAAAAAAGAAGCAGCAGCTTGTAGT
ATGCTTAAGCTTTGGGGAATTTTTTTTTAAGGGGATCTAAAAAAATGTTTTTAGAACATGTAAAATGTTTAATGGTGAAAGTTGGAAAAG
AATTCTTCTGTAAAGTAATACCATGCTAATTATTCGCTTTTAGTAAGTAAAGTAGTGGTTGCTTTAGCAAACCTCTGCTGCCATTTTGCA
GGAATCAACCAGGAACCTTTAGCAGAATTGACAATATGGTGTTGATAAGCATGAAATAATAATAGAAACCTATTCTGCTAGTTTATCTCA
CCCTCTAATTTTTCTCACTAGCATAAATTTTAAATTCCTGATTTGATTTGTCAATAAGATCTTGGCTTATATATGCTGATTTATAGGTAG
TGTCCAAATTATATAGTATAACATATTTTTCTAGTTTCAAAATTTAGTAATGTCCTATTTATGATATATCATTTCTGTGTGTTTGCTATG
TAGTATTACCCAATTAAAAATCTCTAAAAAGAATTAAAGCATTCTAAGAAAAAGGTAAATTTACTATTGCATGGTACAGAAATTTTTTCT

>20577_20577_7_CTTN-DSG1_CTTN_chr11_70269101_ENST00000538675_DSG1_chr18_28906543_ENST00000257192_length(amino acids)=1036AA_BP=3
MDKVVVEVNSEFRIQVRDYNTKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQPPYGIFVIN
QKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLVMILNATDADEPNNLNSK
IAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRDGGADGMSAECECNIKILDVNDNIPYMEQSSYTIEIQENTL
NSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHSIMSQYKLKASAIS
VTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYNMLGGKYQGT
ILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTSTDSSQVYSSEPGNGAKDLLSDNVHFGPAGIGL
LIMGFLVLGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSWAVEGPQPEPRDITTVIPQIPPDNANIIECIDNSGVYTNEYGGREMQ
DLGGGERMTGFELTEGVKTSGMPEICQEYSGTLRRNSMRECREGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSV
GCCSFIGEDLDDSFLDTLGPKFKKLADISLGKESYPDLDPSWPPQSTEPVCLPQETEPVVSGHPPISPHFGTTTVISESTYPSGPGVLHP
KPILDPLGYGNVTVTESYTTSDTLKPSVHVHDNRPASNVVVTERVVGPISGADLHGMLEMPDLRDGSNVIVTERVIAPSSSLPTSLTIHH
PRESSNVVVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVSGAGVTGISGTTGISGGIGSSGLVGTSMGAGSGALSGAGISGGGIGL

--------------------------------------------------------------
>20577_20577_8_CTTN-DSG1_CTTN_chr11_70269101_ENST00000538675_DSG1_chr18_28906544_ENST00000257192_length(transcript)=4942nt_BP=157nt
GCATGAATCCCAAAAAGCAAGAGAACAAACTGCGATTGAGCCTCTTTTTAGCGCTCAGTAGAGCAGGCGCACAGGAAGCAGATGAGAATA
AGCCCGTGCTGACTACTCCAAAGGATTCGGCGGGAAGTATGGGGTGCAGAAGGATCGGATGGATAAGGTGGTGGTAGAAGTTAACAGTGA
ATTCCGAATCCAGGTAAGAGATTATAACACTAAAAATGGCACCATCAAATGGCATTCAATCCGAAGGCAGAAACGTGAATGGATCAAGTT
CGCAGCAGCCTGTCGTGAAGGTGAAGACAACTCAAAGAGGAACCCAATCGCCAAAATTCACTCAGATTGTGCTGCAAACCAGCAAGTTAC
ATACCGCATCTCTGGAGTAGGAATTGATCAGCCACCATATGGGATCTTTGTCATTAATCAGAAAACTGGTGAAATTAATATAACATCCAT
AGTTGATCGAGAGGTCACTCCTTTCTTCATTATCTACTGCCGAGCTCTGAACTCAATGGGCCAAGATTTAGAGAGGCCTCTAGAGCTCAG
AGTCAGGGTTTTGGATATAAATGACAACCCTCCAGTGTTTTCAATGGCTACATTTGCAGGACAAATAGAAGAAAATTCTAATGCAAATAC
ACTGGTGATGATACTCAATGCTACTGACGCAGATGAACCGAACAATTTGAACTCAAAAATAGCCTTCAAGATTATAAGACAAGAACCTTC
AGATTCACCAATGTTTATTATCAACAGAAATACTGGAGAAATTCGAACGATGAATAATTTTCTAGACAGAGAGCAATACGGCCAGTATGC
TCTTGCTGTAAGAGGCTCTGACCGAGATGGCGGGGCAGATGGCATGTCAGCGGAATGTGAGTGCAACATTAAAATCCTCGATGTCAATGA
TAATATCCCTTACATGGAACAGTCTTCATATACCATAGAAATTCAAGAAAATACTCTAAATTCAAATTTGCTCGAGATTAGAGTAATTGA
TTTGGATGAAGAGTTCTCAGCTAACTGGATGGCAGTAATTTTCTTTATCTCTGGAAATGAAGGAAATTGGTTTGAGATAGAAATGAATGA
AAGAACAAATGTGGGAATTTTAAAGGTTGTTAAGCCCTTAGATTATGAAGCTATGCAGAGTCTGCAACTCAGTATTGGTGTCAGAAATAA
AGCTGAATTTCATCATTCAATTATGTCTCAATATAAACTGAAAGCATCTGCAATTTCTGTGACTGTGTTAAATGTAATTGAAGGCCCAGT
GTTTCGTCCAGGTTCAAAGACATATGTTGTAACTGGTAATATGGGATCAAATGATAAAGTGGGAGACTTTGTAGCTACTGACCTGGACAC
AGGTAGACCTTCAACGACTGTTAGGTATGTAATGGGAAATAATCCAGCTGACCTGCTAGCTGTTGATTCAAGAACAGGCAAACTCACTTT
GAAAAATAAAGTTACCAAGGAACAGTACAATATGCTCGGAGGAAAATACCAAGGAACGATTCTCTCTATAGATGATAATCTTCAAAGAAC
TTGCACTGGTACAATTAATATTAACATTCAAAGTTTTGGTAATGACGACAGGACTAATACAGAGCCGAACACTAAAATTACTACCAATAC
TGGCAGACAAGAAAGTACTTCTTCCACTAACTATGATACCAGCACAACTTCTACTGACTCTAGCCAAGTATATTCTTCTGAACCCGGAAA
CGGAGCCAAAGATTTGTTATCAGACAATGTACATTTTGGTCCTGCTGGCATTGGACTCCTCATCATGGGATTCTTGGTCTTAGGATTGGT
CCCATTTTTGATGATCTGTTGTGATTGTGGAGGTGCTCCTCGTAGTGCAGCTGGCTTTGAGCCTGTTCCCGAATGTTCAGATGGAGCAAT
TCATTCATGGGCAGTAGAAGGACCACAGCCTGAACCCAGGGATATAACCACTGTCATACCACAAATACCACCTGATAACGCAAATATAAT
TGAATGCATTGACAACTCAGGAGTTTATACAAATGAGTATGGTGGCAGAGAAATGCAAGATCTGGGAGGAGGAGAGAGAATGACAGGATT
TGAACTAACAGAGGGAGTTAAAACTTCAGGAATGCCTGAGATATGTCAAGAATACTCTGGAACATTAAGAAGAAATTCTATGAGGGAATG
TAGAGAAGGAGGTCTGAATATGAATTTCATGGAAAGCTACTTCTGTCAGAAAGCATATGCTTACGCAGATGAAGATGAAGGACGCCCATC
TAATGACTGTTTGCTCATATATGACATCGAAGGTGTAGGTTCCCCTGCTGGCTCTGTGGGTTGTTGTAGCTTCATTGGAGAAGACCTGGA
TGACAGCTTCTTGGATACCCTGGGACCTAAATTTAAGAAGTTGGCAGACATCAGCCTAGGAAAAGAATCATATCCAGACCTTGATCCTTC
TTGGCCACCACAAAGCACTGAACCAGTTTGCCTTCCTCAGGAAACAGAGCCCGTTGTTAGTGGACACCCACCAATCTCCCCACATTTCGG
CACTACCACAGTAATTTCTGAGAGCACCTATCCCTCGGGACCTGGTGTACTGCATCCTAAGCCTATTCTCGATCCTCTGGGCTATGGTAA
TGTCACTGTGACCGAGTCTTACACCACCTCTGACACTCTGAAGCCCTCTGTGCACGTTCACGATAACCGACCAGCATCAAACGTGGTAGT
GACAGAGAGAGTGGTCGGCCCAATCTCTGGCGCTGATTTGCATGGAATGTTAGAGATGCCTGACTTGCGAGATGGGTCGAATGTTATAGT
GACAGAAAGGGTAATAGCACCAAGCTCTAGTCTACCCACCTCTCTGACTATCCATCATCCTAGAGAGTCTTCAAATGTGGTAGTGACAGA
AAGAGTAATCCAACCAACTTCCGGCATGATAGGTAGTCTGAGTATGCACCCCGAGTTAGCCAATGCCCACAATGTCATTGTGACAGAGAG
GGTTGTTTCTGGTGCTGGCGTAACTGGAATTAGTGGCACCACTGGGATCAGCGGTGGCATAGGCAGCAGTGGCCTGGTTGGCACCAGCAT
GGGTGCTGGGAGCGGTGCCCTGAGTGGAGCTGGCATAAGTGGTGGTGGCATTGGCCTGAGCAGCTTGGGAGGGACAGCCAGCATTGGCCA
CATGAGGAGTTCCTCTGACCATCACTTTAACCAAACCATTGGGTCCGCCTCCCCTAGCACAGCTCGAAGTCGAATCACAAAGTATAGTAC
CGTGCAATATAGCAAGTAGTCAGGACCCCAGCTCACTTTTTCATAGTCATTGTGGTTTAGATCCAATTCCCACCACTAAAAAACCAACAA
TGTGATTTATAACGCACAACTTCGTGCTCAGGTCATCTAGGAGCAAGGTGAGAAATCACAATGAGAAAAATAAATGGAAACACCACTGCT
AGGGGAGAGCTCTCCTTAGCATTCATAAACTTTTCTCTTATATTAGGACTAAGGAACTAAAACTTGAGGCAGAGTCTTCTTTGTGCCTGA
GTGGCCTGTAGTCCATCTCCAGCATGTAACTGGCCTTACGATGGCAATTGGCATCATTCTCCTTGCTCTGTTTTGCTTTTCCATATAGCT
CGAGCAAAATTCAAAAAGAACTAAATATGCAATATATGTTCATATCTATGGGAAAAATCTAAAATGTGTGCCAGATGCCCTGTTGGTTTC
ACAGATAACATAAATAAAAATTCAACCACAGATTTATACAAGGGTTAACCATTTTTTTTAAGTTTGACTACATAGTCAAGTCCACAAGCC
ATCAAGCACTCCTACCTTAATTATTGCACTAGAGAAAATAAATTCCAAATTAGGAAGTGTTTCCTAGGAGGAAAATTCCATTAGAGAGTG
GCAATAGGATGAGGTTTCTTCAGGGTAAACTAGCAATGCCTGAGCCTGAACCTTAATGTGGGGCCTCAGTTAAATCTCCTGTGGAGTCAA
GGATTCTTCTGATTCTAGTGTGTGTTTAGTGATAGATGTAGTCTTGACGAATATTGCTTACTGGTGAGGTTGAGGAATATCACACTCGTC
TTTCCCTTTACCACTGTGGTTTTGACTTAAGAAAGCAAAACTCACTAAGTTTACTTCTCGAATTGAAGCAAGTGAGGCCTGACATGGTTG
TCATCACTAGTGGCAAATGACCTTCCAAGTAAGCAGATGGGAACTGAATTGTGTTTTCAGGTTTTGTTTTTAGTAGGTGATATTCATTCG
TATCCAGCTCTTTATTACATAGCTCTGAAGTTAAAATGATTTACATAGGCCGAGCTGTGGACAAAAAAAAAAGAAGCAGCAGCTTGTAGT
ATGCTTAAGCTTTGGGGAATTTTTTTTTAAGGGGATCTAAAAAAATGTTTTTAGAACATGTAAAATGTTTAATGGTGAAAGTTGGAAAAG
AATTCTTCTGTAAAGTAATACCATGCTAATTATTCGCTTTTAGTAAGTAAAGTAGTGGTTGCTTTAGCAAACCTCTGCTGCCATTTTGCA
GGAATCAACCAGGAACCTTTAGCAGAATTGACAATATGGTGTTGATAAGCATGAAATAATAATAGAAACCTATTCTGCTAGTTTATCTCA
CCCTCTAATTTTTCTCACTAGCATAAATTTTAAATTCCTGATTTGATTTGTCAATAAGATCTTGGCTTATATATGCTGATTTATAGGTAG
TGTCCAAATTATATAGTATAACATATTTTTCTAGTTTCAAAATTTAGTAATGTCCTATTTATGATATATCATTTCTGTGTGTTTGCTATG
TAGTATTACCCAATTAAAAATCTCTAAAAAGAATTAAAGCATTCTAAGAAAAAGGTAAATTTACTATTGCATGGTACAGAAATTTTTTCT

>20577_20577_8_CTTN-DSG1_CTTN_chr11_70269101_ENST00000538675_DSG1_chr18_28906544_ENST00000257192_length(amino acids)=1036AA_BP=3
MDKVVVEVNSEFRIQVRDYNTKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQQVTYRISGVGIDQPPYGIFVIN
QKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLVMILNATDADEPNNLNSK
IAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRDGGADGMSAECECNIKILDVNDNIPYMEQSSYTIEIQENTL
NSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHSIMSQYKLKASAIS
VTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYNMLGGKYQGT
ILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTSTDSSQVYSSEPGNGAKDLLSDNVHFGPAGIGL
LIMGFLVLGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSWAVEGPQPEPRDITTVIPQIPPDNANIIECIDNSGVYTNEYGGREMQ
DLGGGERMTGFELTEGVKTSGMPEICQEYSGTLRRNSMRECREGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSV
GCCSFIGEDLDDSFLDTLGPKFKKLADISLGKESYPDLDPSWPPQSTEPVCLPQETEPVVSGHPPISPHFGTTTVISESTYPSGPGVLHP
KPILDPLGYGNVTVTESYTTSDTLKPSVHVHDNRPASNVVVTERVVGPISGADLHGMLEMPDLRDGSNVIVTERVIAPSSSLPTSLTIHH
PRESSNVVVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVSGAGVTGISGTTGISGGIGSSGLVGTSMGAGSGALSGAGISGGGIGL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for CTTN-DSG1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CTTN-DSG1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CTTN-DSG1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource