FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:CUL2-PARD3 (FusionGDB2 ID:20659)

Fusion Gene Summary for CUL2-PARD3

check button Fusion gene summary
Fusion gene informationFusion gene name: CUL2-PARD3
Fusion gene ID: 20659
HgeneTgene
Gene symbol

CUL2

PARD3

Gene ID

8453

56288

Gene namecullin 2par-3 family cell polarity regulator
Synonyms-ASIP|Baz|PAR3|PAR3alpha|PARD-3|PARD3A|PPP1R118|SE2-5L16|SE2-5LT1|SE2-5T2
Cytomap

10p11.21

10p11.22-p11.21

Type of geneprotein-codingprotein-coding
Descriptioncullin-2CUL-2testis secretory sperm-binding protein Li 238Epartitioning defective 3 homologCTCL tumor antigen se2-5PAR3-alphaatypical PKC isotype-specific interacting proteinbazookapar-3 family cell polarity regulator alphapar-3 partitioning defective 3 homologprotein phosphatase 1, regulatory subunit 118
Modification date2020032720200327
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000374742, ENST00000374746, 
ENST00000374748, ENST00000374749, 
ENST00000374751, ENST00000537177, 
ENST00000602371, ENST00000478044, 
ENST00000340077, ENST00000374768, 
ENST00000374773, ENST00000374776, 
ENST00000466092, ENST00000544292, 
ENST00000346874, ENST00000350537, 
ENST00000374788, ENST00000374789, 
ENST00000374790, ENST00000374794, 
ENST00000545260, ENST00000545693, 
Fusion gene scores* DoF score7 X 7 X 5=24520 X 21 X 8=3360
# samples 824
** MAII scorelog2(8/245*10)=-1.61470984411521
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(24/3360*10)=-3.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CUL2 [Title/Abstract] AND PARD3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCUL2(35333494)-PARD3(34806087), # samples:2
PARD3(35103803)-CUL2(35360267), # samples:2
Anticipated loss of major functional domain due to fusion event.CUL2-PARD3 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
CUL2-PARD3 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
CUL2-PARD3 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
CUL2-PARD3 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
PARD3-CUL2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
PARD3-CUL2 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF.
PARD3-CUL2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
PARD3-CUL2 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CUL2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PARD3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-55-6642-01ACUL2chr10

35333494

-PARD3chr10

34806087

-


Top

Fusion Gene ORF analysis for CUL2-PARD3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000374742ENST00000340077CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374742ENST00000374768CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374742ENST00000374773CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374742ENST00000374776CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374742ENST00000466092CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374742ENST00000544292CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374746ENST00000340077CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374746ENST00000374768CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374746ENST00000374773CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374746ENST00000374776CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374746ENST00000466092CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374746ENST00000544292CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374748ENST00000340077CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374748ENST00000374768CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374748ENST00000374773CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374748ENST00000374776CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374748ENST00000466092CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374748ENST00000544292CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374749ENST00000340077CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374749ENST00000374768CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374749ENST00000374773CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374749ENST00000374776CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374749ENST00000466092CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374749ENST00000544292CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374751ENST00000340077CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374751ENST00000374768CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374751ENST00000374773CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374751ENST00000374776CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374751ENST00000466092CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000374751ENST00000544292CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000537177ENST00000340077CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000537177ENST00000374768CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000537177ENST00000374773CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000537177ENST00000374776CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000537177ENST00000466092CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000537177ENST00000544292CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000602371ENST00000340077CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000602371ENST00000374768CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000602371ENST00000374773CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000602371ENST00000374776CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000602371ENST00000466092CUL2chr10

35333494

-PARD3chr10

34806087

-
5CDS-intronENST00000602371ENST00000544292CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374742ENST00000346874CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374742ENST00000350537CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374742ENST00000374788CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374742ENST00000374789CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374742ENST00000374790CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374742ENST00000374794CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374742ENST00000545260CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374742ENST00000545693CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374748ENST00000346874CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374748ENST00000350537CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374748ENST00000374788CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374748ENST00000374789CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374748ENST00000374790CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374748ENST00000374794CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374748ENST00000545260CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374748ENST00000545693CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374749ENST00000346874CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374749ENST00000350537CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374749ENST00000374788CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374749ENST00000374789CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374749ENST00000374790CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374749ENST00000374794CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374749ENST00000545260CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374749ENST00000545693CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374751ENST00000346874CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374751ENST00000350537CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374751ENST00000374788CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374751ENST00000374789CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374751ENST00000374790CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374751ENST00000374794CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374751ENST00000545260CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000374751ENST00000545693CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000602371ENST00000346874CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000602371ENST00000350537CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000602371ENST00000374788CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000602371ENST00000374789CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000602371ENST00000374790CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000602371ENST00000374794CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000602371ENST00000545260CUL2chr10

35333494

-PARD3chr10

34806087

-
Frame-shiftENST00000602371ENST00000545693CUL2chr10

35333494

-PARD3chr10

34806087

-
In-frameENST00000374746ENST00000346874CUL2chr10

35333494

-PARD3chr10

34806087

-
In-frameENST00000374746ENST00000350537CUL2chr10

35333494

-PARD3chr10

34806087

-
In-frameENST00000374746ENST00000374788CUL2chr10

35333494

-PARD3chr10

34806087

-
In-frameENST00000374746ENST00000374789CUL2chr10

35333494

-PARD3chr10

34806087

-
In-frameENST00000374746ENST00000374790CUL2chr10

35333494

-PARD3chr10

34806087

-
In-frameENST00000374746ENST00000374794CUL2chr10

35333494

-PARD3chr10

34806087

-
In-frameENST00000374746ENST00000545260CUL2chr10

35333494

-PARD3chr10

34806087

-
In-frameENST00000374746ENST00000545693CUL2chr10

35333494

-PARD3chr10

34806087

-
In-frameENST00000537177ENST00000346874CUL2chr10

35333494

-PARD3chr10

34806087

-
In-frameENST00000537177ENST00000350537CUL2chr10

35333494

-PARD3chr10

34806087

-
In-frameENST00000537177ENST00000374788CUL2chr10

35333494

-PARD3chr10

34806087

-
In-frameENST00000537177ENST00000374789CUL2chr10

35333494

-PARD3chr10

34806087

-
In-frameENST00000537177ENST00000374790CUL2chr10

35333494

-PARD3chr10

34806087

-
In-frameENST00000537177ENST00000374794CUL2chr10

35333494

-PARD3chr10

34806087

-
In-frameENST00000537177ENST00000545260CUL2chr10

35333494

-PARD3chr10

34806087

-
In-frameENST00000537177ENST00000545693CUL2chr10

35333494

-PARD3chr10

34806087

-
intron-3CDSENST00000478044ENST00000346874CUL2chr10

35333494

-PARD3chr10

34806087

-
intron-3CDSENST00000478044ENST00000350537CUL2chr10

35333494

-PARD3chr10

34806087

-
intron-3CDSENST00000478044ENST00000374788CUL2chr10

35333494

-PARD3chr10

34806087

-
intron-3CDSENST00000478044ENST00000374789CUL2chr10

35333494

-PARD3chr10

34806087

-
intron-3CDSENST00000478044ENST00000374790CUL2chr10

35333494

-PARD3chr10

34806087

-
intron-3CDSENST00000478044ENST00000374794CUL2chr10

35333494

-PARD3chr10

34806087

-
intron-3CDSENST00000478044ENST00000545260CUL2chr10

35333494

-PARD3chr10

34806087

-
intron-3CDSENST00000478044ENST00000545693CUL2chr10

35333494

-PARD3chr10

34806087

-
intron-intronENST00000478044ENST00000340077CUL2chr10

35333494

-PARD3chr10

34806087

-
intron-intronENST00000478044ENST00000374768CUL2chr10

35333494

-PARD3chr10

34806087

-
intron-intronENST00000478044ENST00000374773CUL2chr10

35333494

-PARD3chr10

34806087

-
intron-intronENST00000478044ENST00000374776CUL2chr10

35333494

-PARD3chr10

34806087

-
intron-intronENST00000478044ENST00000466092CUL2chr10

35333494

-PARD3chr10

34806087

-
intron-intronENST00000478044ENST00000544292CUL2chr10

35333494

-PARD3chr10

34806087

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000374746CUL2chr1035333494-ENST00000545260PARD3chr1034806087-59247362243141430
ENST00000374746CUL2chr1035333494-ENST00000545693PARD3chr1034806087-61467362245361504
ENST00000374746CUL2chr1035333494-ENST00000350537PARD3chr1034806087-60557362244461474
ENST00000374746CUL2chr1035333494-ENST00000346874PARD3chr1034806087-60827362244731483
ENST00000374746CUL2chr1035333494-ENST00000374789PARD3chr1034806087-61937362245841520
ENST00000374746CUL2chr1035333494-ENST00000374790PARD3chr1034806087-60137362244041460
ENST00000374746CUL2chr1035333494-ENST00000374794PARD3chr1034806087-58577362242481408
ENST00000374746CUL2chr1035333494-ENST00000374788PARD3chr1034806087-61847362245751517
ENST00000537177CUL2chr1035333494-ENST00000545260PARD3chr1034806087-60218332044111463
ENST00000537177CUL2chr1035333494-ENST00000545693PARD3chr1034806087-62438332046331537
ENST00000537177CUL2chr1035333494-ENST00000350537PARD3chr1034806087-61528332045431507
ENST00000537177CUL2chr1035333494-ENST00000346874PARD3chr1034806087-61798332045701516
ENST00000537177CUL2chr1035333494-ENST00000374789PARD3chr1034806087-62908332046811553
ENST00000537177CUL2chr1035333494-ENST00000374790PARD3chr1034806087-61108332045011493
ENST00000537177CUL2chr1035333494-ENST00000374794PARD3chr1034806087-59548332043451441
ENST00000537177CUL2chr1035333494-ENST00000374788PARD3chr1034806087-62818332046721550

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000374746ENST00000545260CUL2chr1035333494-PARD3chr1034806087-0.0003730340.999627
ENST00000374746ENST00000545693CUL2chr1035333494-PARD3chr1034806087-0.000472570.99952745
ENST00000374746ENST00000350537CUL2chr1035333494-PARD3chr1034806087-0.0003715250.9996284
ENST00000374746ENST00000346874CUL2chr1035333494-PARD3chr1034806087-0.0002824090.99971753
ENST00000374746ENST00000374789CUL2chr1035333494-PARD3chr1034806087-0.0004163270.99958366
ENST00000374746ENST00000374790CUL2chr1035333494-PARD3chr1034806087-0.0004768090.99952316
ENST00000374746ENST00000374794CUL2chr1035333494-PARD3chr1034806087-0.0002596020.9997404
ENST00000374746ENST00000374788CUL2chr1035333494-PARD3chr1034806087-0.0006222230.9993777
ENST00000537177ENST00000545260CUL2chr1035333494-PARD3chr1034806087-0.0003737680.99962616
ENST00000537177ENST00000545693CUL2chr1035333494-PARD3chr1034806087-0.0004797850.9995202
ENST00000537177ENST00000350537CUL2chr1035333494-PARD3chr1034806087-0.0003758370.99962413
ENST00000537177ENST00000346874CUL2chr1035333494-PARD3chr1034806087-0.0002895640.9997104
ENST00000537177ENST00000374789CUL2chr1035333494-PARD3chr1034806087-0.0004246840.9995753
ENST00000537177ENST00000374790CUL2chr1035333494-PARD3chr1034806087-0.0004819410.99951804
ENST00000537177ENST00000374794CUL2chr1035333494-PARD3chr1034806087-0.0002630680.99973696
ENST00000537177ENST00000374788CUL2chr1035333494-PARD3chr1034806087-0.0006341610.99936587

Top

Fusion Genomic Features for CUL2-PARD3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for CUL2-PARD3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:35333494/chr10:34806087)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePARD3chr10:35333494chr10:34806087ENST000003400771211049_1077741032.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003400771211151_1174741032.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003400771211201_1224741032.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003400771211280_1301741032.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003468741241049_1077741320.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003468741241151_1174741320.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003468741241201_1224741320.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003468741241280_1301741320.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003505371241049_1077741311.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003505371241151_1174741311.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003505371241201_1224741311.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003505371241280_1301741311.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003747761201049_107774989.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003747761201151_117474989.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003747761201201_122474989.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003747761201280_130174989.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003747881251049_1077741354.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003747881251151_1174741354.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003747881251201_1224741354.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003747881251280_1301741354.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003747891251049_1077741357.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003747891251151_1174741357.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003747891251201_1224741357.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003747891251280_1301741357.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003747941211049_1077741245.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003747941211151_1174741245.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003747941211201_1224741245.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000003747941211280_1301741245.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000005452601231049_1077741267.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000005452601231151_1174741267.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000005452601231201_1224741267.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000005452601231280_1301741267.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000005456931241049_1077741341.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000005456931241151_1174741341.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000005456931241201_1224741341.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST000005456931241280_1301741341.0Coiled coilOntology_term=ECO:0000255
TgenePARD3chr10:35333494chr10:34806087ENST00000340077121984_1042741032.0Compositional biasNote=Lys-rich
TgenePARD3chr10:35333494chr10:34806087ENST00000346874124984_1042741320.0Compositional biasNote=Lys-rich
TgenePARD3chr10:35333494chr10:34806087ENST00000350537124984_1042741311.0Compositional biasNote=Lys-rich
TgenePARD3chr10:35333494chr10:34806087ENST00000374776120984_104274989.0Compositional biasNote=Lys-rich
TgenePARD3chr10:35333494chr10:34806087ENST00000374788125984_1042741354.0Compositional biasNote=Lys-rich
TgenePARD3chr10:35333494chr10:34806087ENST00000374789125984_1042741357.0Compositional biasNote=Lys-rich
TgenePARD3chr10:35333494chr10:34806087ENST00000374794121984_1042741245.0Compositional biasNote=Lys-rich
TgenePARD3chr10:35333494chr10:34806087ENST00000545260123984_1042741267.0Compositional biasNote=Lys-rich
TgenePARD3chr10:35333494chr10:34806087ENST00000545693124984_1042741341.0Compositional biasNote=Lys-rich
TgenePARD3chr10:35333494chr10:34806087ENST00000340077121271_359741032.0DomainPDZ 1
TgenePARD3chr10:35333494chr10:34806087ENST00000340077121461_546741032.0DomainPDZ 2
TgenePARD3chr10:35333494chr10:34806087ENST00000340077121590_677741032.0DomainPDZ 3
TgenePARD3chr10:35333494chr10:34806087ENST00000346874124271_359741320.0DomainPDZ 1
TgenePARD3chr10:35333494chr10:34806087ENST00000346874124461_546741320.0DomainPDZ 2
TgenePARD3chr10:35333494chr10:34806087ENST00000346874124590_677741320.0DomainPDZ 3
TgenePARD3chr10:35333494chr10:34806087ENST00000350537124271_359741311.0DomainPDZ 1
TgenePARD3chr10:35333494chr10:34806087ENST00000350537124461_546741311.0DomainPDZ 2
TgenePARD3chr10:35333494chr10:34806087ENST00000350537124590_677741311.0DomainPDZ 3
TgenePARD3chr10:35333494chr10:34806087ENST00000374776120271_35974989.0DomainPDZ 1
TgenePARD3chr10:35333494chr10:34806087ENST00000374776120461_54674989.0DomainPDZ 2
TgenePARD3chr10:35333494chr10:34806087ENST00000374776120590_67774989.0DomainPDZ 3
TgenePARD3chr10:35333494chr10:34806087ENST00000374788125271_359741354.0DomainPDZ 1
TgenePARD3chr10:35333494chr10:34806087ENST00000374788125461_546741354.0DomainPDZ 2
TgenePARD3chr10:35333494chr10:34806087ENST00000374788125590_677741354.0DomainPDZ 3
TgenePARD3chr10:35333494chr10:34806087ENST00000374789125271_359741357.0DomainPDZ 1
TgenePARD3chr10:35333494chr10:34806087ENST00000374789125461_546741357.0DomainPDZ 2
TgenePARD3chr10:35333494chr10:34806087ENST00000374789125590_677741357.0DomainPDZ 3
TgenePARD3chr10:35333494chr10:34806087ENST00000374794121271_359741245.0DomainPDZ 1
TgenePARD3chr10:35333494chr10:34806087ENST00000374794121461_546741245.0DomainPDZ 2
TgenePARD3chr10:35333494chr10:34806087ENST00000374794121590_677741245.0DomainPDZ 3
TgenePARD3chr10:35333494chr10:34806087ENST00000545260123271_359741267.0DomainPDZ 1
TgenePARD3chr10:35333494chr10:34806087ENST00000545260123461_546741267.0DomainPDZ 2
TgenePARD3chr10:35333494chr10:34806087ENST00000545260123590_677741267.0DomainPDZ 3
TgenePARD3chr10:35333494chr10:34806087ENST00000545693124271_359741341.0DomainPDZ 1
TgenePARD3chr10:35333494chr10:34806087ENST00000545693124461_546741341.0DomainPDZ 2
TgenePARD3chr10:35333494chr10:34806087ENST00000545693124590_677741341.0DomainPDZ 3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


Top

Fusion Gene Sequence for CUL2-PARD3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>20659_20659_1_CUL2-PARD3_CUL2_chr10_35333494_ENST00000374746_PARD3_chr10_34806087_ENST00000346874_length(transcript)=6082nt_BP=736nt
ATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACAATAAAAGC
CGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCTGAACCCCT
TGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAAGAACAAGT
ACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACCCAGTTTAT
TAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGAGAGCTAGC
ATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGATCGTGGTGG
AGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTAAAGTTTTA
TCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCAAACTGCTC
ACAGTATATGGAAAAGCTGGTAGCAGTGTTTGATGAGCAGGATCCACATCACGGAGGTGATGGCACCAGTGCCAGTTCCACGGGTACCCA
GAGCCCAGAGATATTTGGTAGTGAGCTTGGCACCAACAATGTCTCAGCCTTTCAGCCTTACCAAGCAACAAGTGAAATTGAGGTCACACC
TTCAGTCCTTCGAGCAAATATGCCTCTTCATGTTCGACGCAGTAGTGACCCAGCTCTAATTGGCCTCTCCACTTCTGTCAGTGATAGTAA
TTTTTCCTCTGAAGAGCCTTCAAGGAAAAATCCCACACGCTGGTCAACAACAGCTGGCTTCCTCAAGCAGAACACTGCTGGGAGTCCTAA
AACCTGCGACAGGAAGAAAGATGAAAACTACAGAAGCCTCCCGCGGGATACTAGTAACTGGTCTAACCAATTTCAGAGAGACAATGCTCG
CTCGTCTCTGAGTGCCAGTCACCCAATGGTGGGCAAGTGGCTGGAGAAACAAGAACAGGATGAGGATGGGACAGAAGAGGATAACAGTCG
TGTTGAACCTGTTGGACATGCTGACACGGGTTTGGAGCATATACCCAACTTTTCTCTGGATGATATGGTAAAGCTCGTAGAAGTCCCCAA
CGATGGAGGGCCTCTGGGAATCCACGTAGTGCCTTTCAGTGCTCGAGGCGGCAGAACCCTGGGGTTATTAGTAAAACGATTGGAGAAAGG
TGGTAAAGCTGAACATGAAAATCTTTTTCGTGAGAATGATTGCATTGTCAGGATTAATGATGGCGACCTTCGAAATAGAAGATTTGAACA
AGCACAACATATGTTTCGCCAAGCCATGCGTACACCCATCATTTGGTTCCATGTGGTTCCTGCAGCAAATAAAGAGCAGTATGAACAACT
ATCCCAAAGTGAGAAGAACAATTACTATTCAAGCCGTTTTAGCCCTGACAGCCAGTATATTGACAACAGGAGTGTGAACAGTGCAGGGCT
TCACACGGTGCAGAGAGCACCCCGACTGAACCACCCGCCTGAGCAGATAGACTCTCACTCAAGACTACCTCATAGCGCACACCCCTCGGG
AAAACCACCATCCGCTCCAGCCTCGGCACCTCAGAATGTATTTAGTACGACTGTAAGCAGTGGTTATAACACCAAAAAAATAGGCAAGAG
GCTTAATATCCAGCTTAAGAAAGGTACAGAAGGTTTGGGATTCAGCATCACTTCCAGAGATGTAACAATAGGTGGCTCAGCTCCAATCTA
TGTGAAAAACATTCTCCCCCGGGGGGCGGCCATTCAGGATGGCCGACTTAAGGCAGGAGACAGACTTATAGAGGTAAATGGAGTAGATTT
AGTGGGCAAATCCCAAGAGGAAGTTGTTTCGCTGTTGAGAAGCACCAAGATGGAAGGAACTGTGAGCCTTCTGGTCTTTCGCCAGGAAGA
CGCCTTCCACCCAAGGGAACTGAATGCAGAGCCAAGCCAGATGCAGATTCCAAAAGAAACGAAAGCAGAAGATGAGGATATTGTTCTTAC
ACCTGATGGCACCAGGGAATTTCTGACATTTGAAGTCCCACTTAATGATTCAGGATCTGCAGGCCTTGGTGTCAGTGTCAAAGGTAACCG
GTCAAAAGAGAACCACGCAGATTTGGGAATCTTTGTCAAGTCCATTATTAATGGAGGAGCAGCATCTAAAGATGGAAGGCTTCGGGTGAA
TGATCAACTGATAGCAGTAAATGGAGAATCCCTGTTGGGCAAGACAAACCAAGATGCCATGGAAACCCTAAGAAGGTCTATGTCTACTGA
AGGCAATAAACGAGGAATGATCCAGCTTATTGTTGCAAGGAGAATAAGCAAGTGCAATGAGCTGAAGTCACCTGGGAGCCCCCCTGGACC
TGAGCTGCCCATTGAAACAGCGTTGGATGATAGAGAACGAAGAATTTCCCATTCCCTCTACAGTGGGATTGAGGGGCTTGATGAATCGCC
CAGCAGAAATGCTGCCCTCAGTAGGATAATGGGTGAGTCAGGTAAATACCAGCTGTCCCCTACAGTGAATATGCCCCAAGATGACACTGT
CATTATAGAAGATGACAGGTTGCCAGTGCTTCCTCCACATCTCTCTGACCAGTCCTCTTCCAGCTCCCATGATGATGTGGGGTTTGTGAC
GGCAGATGCTGGTACTTGGGCCAAGGCTGCAATCAGTGATTCAGCCGACTGCTCTTTGAGTCCAGATGTTGATCCAGTTCTTGCTTTTCA
ACGAGAAGGATTTGGACGTCAGAGTATGTCAGAAAAACGCACAAAGCAATTTTCAGATGCCAGTCAATTGGATTTCGTTAAAACACGAAA
ATCAAAAAGCATGGATTTAGGTATAGCTGACGAGACTAAACTCAATACAGTGGATGACCAGAAAGCAGGTTCTCCCAGCAGAGATGTGGG
TCCTTCCCTGGGTCTGAAGAAGTCAAGCTCGTTGGAGAGTCTGCAGACCGCAGTTGCCGAGGTGACTTTGAATGGGGATATTCCTTTCCA
TCGTCCACGGCCGCGGATAATCAGAGGCAGGGGATGCAATGAGAGCTTCAGAGCTGCCATCGACAAATCTTATGATAAACCCGCGGTAGA
TGATGATGATGAAGGCATGGAGACCTTGGAAGAAGACACAGAAGAAAGTTCAAGATCAGGGAGAGAGTCTGTATCCACAGCCAGTGATCA
GCCTTCCCACTCTCTGGAGAGACAAATGAATGGAAACCAAGAGAAAGGTGATAAGACTGATAGAAAAAAGGATAAAACTGGAAAAGAAAA
GAAGAAAGATAGAGATAAGGAGAAGGATAAAATGAAAGCCAAGAAGGGAATGCTGAAGGGCTTGGGAGACATGTTCAGGATTCAAGCCAA
AACTCGAGAATTTAGGGAACGACAAGCTCGAGAGCGTGACTATGCTGAAATTCAAGATTTTCATCGGACATTTGGCTGTGATGATGAGTT
AATGTATGGGGGAGTTTCTTCTTATGAAGGTTCCATGGCTCTCAACGCTAGACCTCAGAGCCCACGAGAAGGGCATATGATGGATGCTTT
GTATGCCCAAGTCAAGAAGCCGCGGAATTCCAAACCCTCACCTGTAGACAGTAACAGATCAACTCCTAGCAATCATGATCGGATACAGCG
TCTGAGGCAAGAATTTCAGCAAGCAAAGCAAGATGAAGATGTAGAAGATCGTCGGCGGACCTATAGTTTTGAGCAACCCTGGCCGAACGC
ACGGCCGGCGACGCAGAGCGGGCGACACTCGGTGTCCGTGGAGGTGCAGATGCAGCGGCAGCGGCAGGAGGAGCGCGAGAGCTCCCAGCA
GGCCCAGCGCCAGTACAGCTCTCTGCCTCGGCAAAGCAGGAAAAATGCCAGCTCGGTCTCCCAGGACTCTTGGGAGCAGAACTACTCCCC
TGGGGAAGGCTTCCAGAGTGCCAAAGAGAACCCCAGGTACTCCAGCTACCAAGGCTCCAGGAACGGCTACCTGGGAGGACATGGCTTCAA
CGCCAGGGTCATGCTGGAAACTCAGGAGCTCCTTCGCCAGGAACAGAGGCGGAAGGAGCAGCAGATGAAGAAGCAGCCTCCTTCCGAGGG
GCCCAGCAACTATGACTCGTATAAGAAAGTCCAGGACCCCAGTTACGCCCCTCCCAAGGGGCCCTTCCGGCAAGATGTGCCCCCCTCCCC
TTCTCAGGTTGCGAGGCTGAACAGACTTCAGACTCCTGAGAAAGGGAGGCCCTTCTATTCCTGAGCACGCAAATAACGGATGCTTCATGT
CGCGCAATAAAAGACATTTTCCTATGAAGACTTGTATTTTGGGAGTTTTTTTAAAACCTCGATGGTACTATGGAGTATTTCTGTTGTTGG
TATCAGTGCCTTTAAGCGGTGTAGGCAAAGAAATGGAAGGCCTTAATGTCTTTGCCACTATGTCTCAAGTGTCTGTTTCATGGAAGGATT
TCCCACCCTGTGACAATCATCTGTTTGAGGTGTTCATATGCTCTGCGCCTCTCCACAGTACCAGGAATCTCGGCCCTACTCATGAGTTGT
CCGCGGCTTGGTTGTAACATCCCTGCACCACTTGCAGTGACAAATTCACCTGAAGTGGAGGATGACGTGCGGCCCTGTTTCTCCCTCTAA
GTTCTCTTAGCTATGGGATGACATCTTAGTCTCTGGTGGAGGAAAAGTGGGCGACATACACCAAAAATTGGGGCTTTCTGGTACTTCACA
GCACAGCCATTTGTCGTACTTTGTCATCACTGTGGTTTTCTCTTTCCTTTCTCAGCTCTTTGTGACGGGAGAGTCGGTCATCCTATTACA
GAAGCTAAGCCATAGTCCAACATTGTTTGGTCACCATGGGGGTCCTTTTGTAACTGCCTTATGACTCAACATTACCAATAAAGTGATGAT
CCTGGTCTGCGTTTATACATACGCTTGTTCGGTCCTGTTCCTGACACGTGGGTTGAGTCACCACAGCTCTGTGTGGGGAACGTGGGAGAC
AGGAGTGGCTCCTGCCGGGGGAAGCTGGGCCTGCCATTGGCCCTGTGTCTATCATGAGGGGAGAGCTAAGAAAGAAATTCTCCTAGGAAG
AGCTCATGGCCCAGTACATCCTAGTAATTATTTTAATTAGTTTTTGTTCTGACAGCTTGTCAGGAAGGGCACAGAATGGGACAGAGATAA
ACCAGACAGTCATTTTGATCTGCTCTCTACGGTTTTTCAAGTCAGAGGCAATTGATGCTTGTCTAATGCATCCACACACTGCATGTCTGA
CTGGCGATGCCGCGCTCCTAAGTAGTTCTGCCATGAAACATAAAAGACAAAGGAAAAGCCGTTACACATCACACAGAGAACATTTTCGGG
TCCCACAGCGGTGGTGGCAGGAAGCTCACTCTCGCGTCAGTATTAGAGTGTGTGTGTGGGTCTCGGGGATCTCGGTGGCTCCCATCTTCC
TTCATTGTTCTGAACATCCTGTATTGTAAACCATGGCTGGGGTGCTAAAGTGCCTGTGAATCCCGATGTGGAAAAAGCTGGAGGTGAAAG
CTCAGCATACCATGTATTTACTTTAAAAACAGAAAAAAAGACATGTATGGATATGTCTATTTTTTTTTTATTGGCACATTGTATTTTTGT
GTTGACTTGTTTTTAGAAATGATGTGTCCACACACGTACCCGTGTCTCTTCTGCATTTCTGTGTCATGGTTCTGTTTCTTAATCACGTGC
GGCGGTGTCTAAGTGGTGTTACCAGTGTACGCGCAGTGACCTTGGATGACAGTGGCTCTTTCTCACAGCCTCCCCTGAGCTGTGAGAAAC

>20659_20659_1_CUL2-PARD3_CUL2_chr10_35333494_ENST00000374746_PARD3_chr10_34806087_ENST00000346874_length(amino acids)=1483AA_BP=0
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVRHLHKRVLESEEQVLVMYHRY
WEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQAILIRMLLREIKNDRGGEDPNQKV
IHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYMEKLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGS
ELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKD
ENYRSLPRDTSNWSNQFQRDNARSSLSASHPMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGI
HVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNN
YYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKK
GTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPREL
NAEPSQMQIPKETKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVN
GESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALS
RIMGESGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQ
SMSEKRTKQFSDASQLDFVKTRKSKSMDLGIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRII
RGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKE
KDKMKAKKGMLKGLGDMFRIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKP
RNSKPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRRTYSFEQPWPNARPATQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSS
LPRQSRKNASSVSQDSWEQNYSPGEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVMLETQELLRQEQRRKEQQMKKQPPSEGPSNYDSY

--------------------------------------------------------------
>20659_20659_2_CUL2-PARD3_CUL2_chr10_35333494_ENST00000374746_PARD3_chr10_34806087_ENST00000350537_length(transcript)=6055nt_BP=736nt
ATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACAATAAAAGC
CGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCTGAACCCCT
TGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAAGAACAAGT
ACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACCCAGTTTAT
TAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGAGAGCTAGC
ATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGATCGTGGTGG
AGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTAAAGTTTTA
TCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCAAACTGCTC
ACAGTATATGGAAAAGCTGGTAGCAGTGTTTGATGAGCAGGATCCACATCACGGAGGTGATGGCACCAGTGCCAGTTCCACGGGTACCCA
GAGCCCAGAGATATTTGGTAGTGAGCTTGGCACCAACAATGTCTCAGCCTTTCAGCCTTACCAAGCAACAAGTGAAATTGAGGTCACACC
TTCAGTCCTTCGAGCAAATATGCCTCTTCATGTTCGACGCAGTAGTGACCCAGCTCTAATTGGCCTCTCCACTTCTGTCAGTGATAGTAA
TTTTTCCTCTGAAGAGCCTTCAAGGAAAAATCCCACACGCTGGTCAACAACAGCTGGCTTCCTCAAGCAGAACACTGCTGGGAGTCCTAA
AACCTGCGACAGGAAGAAAGATGAAAACTACAGAAGCCTCCCGCGGGATACTAGTAACTGGTCTAACCAATTTCAGAGAGACAATGCTCG
CTCGTCTCTGAGTGCCAGTCACCCAATGGTGGGCAAGTGGCTGGAGAAACAAGAACAGGATGAGGATGGGACAGAAGAGGATAACAGTCG
TGTTGAACCTGTTGGACATGCTGACACGGGTTTGGAGCATATACCCAACTTTTCTCTGGATGATATGGTAAAGCTCGTAGAAGTCCCCAA
CGATGGAGGGCCTCTGGGAATCCACGTAGTGCCTTTCAGTGCTCGAGGCGGCAGAACCCTGGGGTTATTAGTAAAACGATTGGAGAAAGG
TGGTAAAGCTGAACATGAAAATCTTTTTCGTGAGAATGATTGCATTGTCAGGATTAATGATGGCGACCTTCGAAATAGAAGATTTGAACA
AGCACAACATATGTTTCGCCAAGCCATGCGTACACCCATCATTTGGTTCCATGTGGTTCCTGCAGCAAATAAAGAGCAGTATGAACAACT
ATCCCAAAGTGAGAAGAACAATTACTATTCAAGCCGTTTTAGCCCTGACAGCCAGTATATTGACAACAGGAGTGTGAACAGTGCAGGGCT
TCACACGGTGCAGAGAGCACCCCGACTGAACCACCCGCCTGAGCAGATAGACTCTCACTCAAGACTACCTCATAGCGCACACCCCTCGGG
AAAACCACCATCCGCTCCAGCCTCGGCACCTCAGAATGTATTTAGTACGACTGTAAGCAGTGGTTATAACACCAAAAAAATAGGCAAGAG
GCTTAATATCCAGCTTAAGAAAGGTACAGAAGGTTTGGGATTCAGCATCACTTCCAGAGATGTAACAATAGGTGGCTCAGCTCCAATCTA
TGTGAAAAACATTCTCCCCCGGGGGGCGGCCATTCAGGATGGCCGACTTAAGGCAGGAGACAGACTTATAGAGGTAAATGGAGTAGATTT
AGTGGGCAAATCCCAAGAGGAAGTTGTTTCGCTGTTGAGAAGCACCAAGATGGAAGGAACTGTGAGCCTTCTGGTCTTTCGCCAGGAAGA
CGCCTTCCACCCAAGGGAACTGAAAGCAGAAGATGAGGATATTGTTCTTACACCTGATGGCACCAGGGAATTTCTGACATTTGAAGTCCC
ACTTAATGATTCAGGATCTGCAGGCCTTGGTGTCAGTGTCAAAGGTAACCGGTCAAAAGAGAACCACGCAGATTTGGGAATCTTTGTCAA
GTCCATTATTAATGGAGGAGCAGCATCTAAAGATGGAAGGCTTCGGGTGAATGATCAACTGATAGCAGTAAATGGAGAATCCCTGTTGGG
CAAGACAAACCAAGATGCCATGGAAACCCTAAGAAGGTCTATGTCTACTGAAGGCAATAAACGAGGAATGATCCAGCTTATTGTTGCAAG
GAGAATAAGCAAGTGCAATGAGCTGAAGTCACCTGGGAGCCCCCCTGGACCTGAGCTGCCCATTGAAACAGCGTTGGATGATAGAGAACG
AAGAATTTCCCATTCCCTCTACAGTGGGATTGAGGGGCTTGATGAATCGCCCAGCAGAAATGCTGCCCTCAGTAGGATAATGGGTAAATA
CCAGCTGTCCCCTACAGTGAATATGCCCCAAGATGACACTGTCATTATAGAAGATGACAGGTTGCCAGTGCTTCCTCCACATCTCTCTGA
CCAGTCCTCTTCCAGCTCCCATGATGATGTGGGGTTTGTGACGGCAGATGCTGGTACTTGGGCCAAGGCTGCAATCAGTGATTCAGCCGA
CTGCTCTTTGAGTCCAGATGTTGATCCAGTTCTTGCTTTTCAACGAGAAGGATTTGGACGTCAGATAGCTGACGAGACTAAACTCAATAC
AGTGGATGACCAGAAAGCAGGTTCTCCCAGCAGAGATGTGGGTCCTTCCCTGGGTCTGAAGAAGTCAAGCTCGTTGGAGAGTCTGCAGAC
CGCAGTTGCCGAGGTGACTTTGAATGGGGATATTCCTTTCCATCGTCCACGGCCGCGGATAATCAGAGGCAGGGGATGCAATGAGAGCTT
CAGAGCTGCCATCGACAAATCTTATGATAAACCCGCGGTAGATGATGATGATGAAGGCATGGAGACCTTGGAAGAAGACACAGAAGAAAG
TTCAAGATCAGGGAGAGAGTCTGTATCCACAGCCAGTGATCAGCCTTCCCACTCTCTGGAGAGACAAATGAATGGAAACCAAGAGAAAGG
TGATAAGACTGATAGAAAAAAGGATAAAACTGGAAAAGAAAAGAAGAAAGATAGAGATAAGGAGAAGGATAAAATGAAAGCCAAGAAGGG
AATGCTGAAGGGCTTGGGAGACATGTTCAGGTTTGGCAAACATCGAAAAGATGACAAGATTGAGAAAACGGGTAAAATAAAAATACAGGA
ATCCTTTACATCAGAAGAGGAGAGGATACGAATGAAGCAGGAGCAGGAGAGGATTCAAGCCAAAACTCGAGAATTTAGGGAACGACAAGC
TCGAGAGCGTGACTATGCTGAAATTCAAGATTTTCATCGGACATTTGGCTGTGATGATGAGTTAATGTATGGGGGAGTTTCTTCTTATGA
AGGTTCCATGGCTCTCAACGCTAGACCTCAGAGCCCACGAGAAGGGCATATGATGGATGCTTTGTATGCCCAAGTCAAGAAGCCGCGGAA
TTCCAAACCCTCACCTGTAGACAGTAACAGATCAACTCCTAGCAATCATGATCGGATACAGCGTCTGAGGCAAGAATTTCAGCAAGCAAA
GCAAGATGAAGATGTAGAAGATCGTCGGCGGACCTATAGTTTTGAGCAACCCTGGCCGAACGCACGGCCGGCGACGCAGAGCGGGCGACA
CTCGGTGTCCGTGGAGGTGCAGATGCAGCGGCAGCGGCAGGAGGAGCGCGAGAGCTCCCAGCAGGCCCAGCGCCAGTACAGCTCTCTGCC
TCGGCAAAGCAGGAAAAATGCCAGCTCGGTCTCCCAGGACTCTTGGGAGCAGAACTACTCCCCTGGGGAAGGCTTCCAGAGTGCCAAAGA
GAACCCCAGGTACTCCAGCTACCAAGGCTCCAGGAACGGCTACCTGGGAGGACATGGCTTCAACGCCAGGGTCATGCTGGAAACTCAGGA
GCTCCTTCGCCAGGAACAGAGGCGGAAGGAGCAGCAGATGAAGAAGCAGCCTCCTTCCGAGGGGCCCAGCAACTATGACTCGTATAAGAA
AGTCCAGGACCCCAGTTACGCCCCTCCCAAGGGGCCCTTCCGGCAAGATGTGCCCCCCTCCCCTTCTCAGGTTGCGAGGCTGAACAGACT
TCAGACTCCTGAGAAAGGGAGGCCCTTCTATTCCTGAGCACGCAAATAACGGATGCTTCATGTCGCGCAATAAAAGACATTTTCCTATGA
AGACTTGTATTTTGGGAGTTTTTTTAAAACCTCGATGGTACTATGGAGTATTTCTGTTGTTGGTATCAGTGCCTTTAAGCGGTGTAGGCA
AAGAAATGGAAGGCCTTAATGTCTTTGCCACTATGTCTCAAGTGTCTGTTTCATGGAAGGATTTCCCACCCTGTGACAATCATCTGTTTG
AGGTGTTCATATGCTCTGCGCCTCTCCACAGTACCAGGAATCTCGGCCCTACTCATGAGTTGTCCGCGGCTTGGTTGTAACATCCCTGCA
CCACTTGCAGTGACAAATTCACCTGAAGTGGAGGATGACGTGCGGCCCTGTTTCTCCCTCTAAGTTCTCTTAGCTATGGGATGACATCTT
AGTCTCTGGTGGAGGAAAAGTGGGCGACATACACCAAAAATTGGGGCTTTCTGGTACTTCACAGCACAGCCATTTGTCGTACTTTGTCAT
CACTGTGGTTTTCTCTTTCCTTTCTCAGCTCTTTGTGACGGGAGAGTCGGTCATCCTATTACAGAAGCTAAGCCATAGTCCAACATTGTT
TGGTCACCATGGGGGTCCTTTTGTAACTGCCTTATGACTCAACATTACCAATAAAGTGATGATCCTGGTCTGCGTTTATACATACGCTTG
TTCGGTCCTGTTCCTGACACGTGGGTTGAGTCACCACAGCTCTGTGTGGGGAACGTGGGAGACAGGAGTGGCTCCTGCCGGGGGAAGCTG
GGCCTGCCATTGGCCCTGTGTCTATCATGAGGGGAGAGCTAAGAAAGAAATTCTCCTAGGAAGAGCTCATGGCCCAGTACATCCTAGTAA
TTATTTTAATTAGTTTTTGTTCTGACAGCTTGTCAGGAAGGGCACAGAATGGGACAGAGATAAACCAGACAGTCATTTTGATCTGCTCTC
TACGGTTTTTCAAGTCAGAGGCAATTGATGCTTGTCTAATGCATCCACACACTGCATGTCTGACTGGCGATGCCGCGCTCCTAAGTAGTT
CTGCCATGAAACATAAAAGACAAAGGAAAAGCCGTTACACATCACACAGAGAACATTTTCGGGTCCCACAGCGGTGGTGGCAGGAAGCTC
ACTCTCGCGTCAGTATTAGAGTGTGTGTGTGGGTCTCGGGGATCTCGGTGGCTCCCATCTTCCTTCATTGTTCTGAACATCCTGTATTGT
AAACCATGGCTGGGGTGCTAAAGTGCCTGTGAATCCCGATGTGGAAAAAGCTGGAGGTGAAAGCTCAGCATACCATGTATTTACTTTAAA
AACAGAAAAAAAGACATGTATGGATATGTCTATTTTTTTTTTATTGGCACATTGTATTTTTGTGTTGACTTGTTTTTAGAAATGATGTGT
CCACACACGTACCCGTGTCTCTTCTGCATTTCTGTGTCATGGTTCTGTTTCTTAATCACGTGCGGCGGTGTCTAAGTGGTGTTACCAGTG
TACGCGCAGTGACCTTGGATGACAGTGGCTCTTTCTCACAGCCTCCCCTGAGCTGTGAGAAACAGCTTTCTCTGTACATATGCAACTCCT

>20659_20659_2_CUL2-PARD3_CUL2_chr10_35333494_ENST00000374746_PARD3_chr10_34806087_ENST00000350537_length(amino acids)=1474AA_BP=0
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVRHLHKRVLESEEQVLVMYHRY
WEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQAILIRMLLREIKNDRGGEDPNQKV
IHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYMEKLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGS
ELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKD
ENYRSLPRDTSNWSNQFQRDNARSSLSASHPMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGI
HVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNN
YYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKK
GTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPREL
KAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAM
ETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGKYQLSPTVN
MPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQIADETKLNTVDDQKAG
SPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRES
VSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEE
RIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVD
SNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRRTYSFEQPWPNARPATQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNA
SSVSQDSWEQNYSPGEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVMLETQELLRQEQRRKEQQMKKQPPSEGPSNYDSYKKVQDPSYA

--------------------------------------------------------------
>20659_20659_3_CUL2-PARD3_CUL2_chr10_35333494_ENST00000374746_PARD3_chr10_34806087_ENST00000374788_length(transcript)=6184nt_BP=736nt
ATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACAATAAAAGC
CGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCTGAACCCCT
TGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAAGAACAAGT
ACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACCCAGTTTAT
TAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGAGAGCTAGC
ATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGATCGTGGTGG
AGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTAAAGTTTTA
TCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCAAACTGCTC
ACAGTATATGGAAAAGCTGGTAGCAGTGTTTGATGAGCAGGATCCACATCACGGAGGTGATGGCACCAGTGCCAGTTCCACGGGTACCCA
GAGCCCAGAGATATTTGGTAGTGAGCTTGGCACCAACAATGTCTCAGCCTTTCAGCCTTACCAAGCAACAAGTGAAATTGAGGTCACACC
TTCAGTCCTTCGAGCAAATATGCCTCTTCATGTTCGACGCAGTAGTGACCCAGCTCTAATTGGCCTCTCCACTTCTGTCAGTGATAGTAA
TTTTTCCTCTGAAGAGCCTTCAAGGAAAAATCCCACACGCTGGTCAACAACAGCTGGCTTCCTCAAGCAGAACACTGCTGGGAGTCCTAA
AACCTGCGACAGGAAGAAAGATGAAAACTACAGAAGCCTCCCGCGGGATACTAGTAACTGGTCTAACCAATTTCAGAGAGACAATGCTCG
CTCGTCTCTGAGTGCCAGTCACCCAATGGTGGGCAAGTGGCTGGAGAAACAAGAACAGGATGAGGATGGGACAGAAGAGGATAACAGTCG
TGTTGAACCTGTTGGACATGCTGACACGGGTTTGGAGCATATACCCAACTTTTCTCTGGATGATATGGTAAAGCTCGTAGAAGTCCCCAA
CGATGGAGGGCCTCTGGGAATCCACGTAGTGCCTTTCAGTGCTCGAGGCGGCAGAACCCTGGGGTTATTAGTAAAACGATTGGAGAAAGG
TGGTAAAGCTGAACATGAAAATCTTTTTCGTGAGAATGATTGCATTGTCAGGATTAATGATGGCGACCTTCGAAATAGAAGATTTGAACA
AGCACAACATATGTTTCGCCAAGCCATGCGTACACCCATCATTTGGTTCCATGTGGTTCCTGCAGCAAATAAAGAGCAGTATGAACAACT
ATCCCAAAGTGAGAAGAACAATTACTATTCAAGCCGTTTTAGCCCTGACAGCCAGTATATTGACAACAGGAGTGTGAACAGTGCAGGGCT
TCACACGGTGCAGAGAGCACCCCGACTGAACCACCCGCCTGAGCAGATAGACTCTCACTCAAGACTACCTCATAGCGCACACCCCTCGGG
AAAACCACCATCCGCTCCAGCCTCGGCACCTCAGAATGTATTTAGTACGACTGTAAGCAGTGGTTATAACACCAAAAAAATAGGCAAGAG
GCTTAATATCCAGCTTAAGAAAGGTACAGAAGGTTTGGGATTCAGCATCACTTCCAGAGATGTAACAATAGGTGGCTCAGCTCCAATCTA
TGTGAAAAACATTCTCCCCCGGGGGGCGGCCATTCAGGATGGCCGACTTAAGGCAGGAGACAGACTTATAGAGGTAAATGGAGTAGATTT
AGTGGGCAAATCCCAAGAGGAAGTTGTTTCGCTGTTGAGAAGCACCAAGATGGAAGGAACTGTGAGCCTTCTGGTCTTTCGCCAGGAAGA
CGCCTTCCACCCAAGGGAACTGAATGCAGAGCCAAGCCAGATGCAGATTCCAAAAGAAACGAAAGCAGAAGATGAGGATATTGTTCTTAC
ACCTGATGGCACCAGGGAATTTCTGACATTTGAAGTCCCACTTAATGATTCAGGATCTGCAGGCCTTGGTGTCAGTGTCAAAGGTAACCG
GTCAAAAGAGAACCACGCAGATTTGGGAATCTTTGTCAAGTCCATTATTAATGGAGGAGCAGCATCTAAAGATGGAAGGCTTCGGGTGAA
TGATCAACTGATAGCAGTAAATGGAGAATCCCTGTTGGGCAAGACAAACCAAGATGCCATGGAAACCCTAAGAAGGTCTATGTCTACTGA
AGGCAATAAACGAGGAATGATCCAGCTTATTGTTGCAAGGAGAATAAGCAAGTGCAATGAGCTGAAGTCACCTGGGAGCCCCCCTGGACC
TGAGCTGCCCATTGAAACAGCGTTGGATGATAGAGAACGAAGAATTTCCCATTCCCTCTACAGTGGGATTGAGGGGCTTGATGAATCGCC
CAGCAGAAATGCTGCCCTCAGTAGGATAATGGGTAAATACCAGCTGTCCCCTACAGTGAATATGCCCCAAGATGACACTGTCATTATAGA
AGATGACAGGTTGCCAGTGCTTCCTCCACATCTCTCTGACCAGTCCTCTTCCAGCTCCCATGATGATGTGGGGTTTGTGACGGCAGATGC
TGGTACTTGGGCCAAGGCTGCAATCAGTGATTCAGCCGACTGCTCTTTGAGTCCAGATGTTGATCCAGTTCTTGCTTTTCAACGAGAAGG
ATTTGGACGTCAGAGTATGTCAGAAAAACGCACAAAGCAATTTTCAGATGCCAGTCAATTGGATTTCGTTAAAACACGAAAATCAAAAAG
CATGGATTTAGGTATAGCTGACGAGACTAAACTCAATACAGTGGATGACCAGAAAGCAGGTTCTCCCAGCAGAGATGTGGGTCCTTCCCT
GGGTCTGAAGAAGTCAAGCTCGTTGGAGAGTCTGCAGACCGCAGTTGCCGAGGTGACTTTGAATGGGGATATTCCTTTCCATCGTCCACG
GCCGCGGATAATCAGAGGCAGGGGATGCAATGAGAGCTTCAGAGCTGCCATCGACAAATCTTATGATAAACCCGCGGTAGATGATGATGA
TGAAGGCATGGAGACCTTGGAAGAAGACACAGAAGAAAGTTCAAGATCAGGGAGAGAGTCTGTATCCACAGCCAGTGATCAGCCTTCCCA
CTCTCTGGAGAGACAAATGAATGGAAACCAAGAGAAAGGTGATAAGACTGATAGAAAAAAGGATAAAACTGGAAAAGAAAAGAAGAAAGA
TAGAGATAAGGAGAAGGATAAAATGAAAGCCAAGAAGGGAATGCTGAAGGGCTTGGGAGACATGTTCAGGTTTGGCAAACATCGAAAAGA
TGACAAGATTGAGAAAACGGGTAAAATAAAAATACAGGAATCCTTTACATCAGAAGAGGAGAGGATACGAATGAAGCAGGAGCAGGAGAG
GATTCAAGCCAAAACTCGAGAATTTAGGGAACGACAAGCTCGAGAGCGTGACTATGCTGAAATTCAAGATTTTCATCGGACATTTGGCTG
TGATGATGAGTTAATGTATGGGGGAGTTTCTTCTTATGAAGGTTCCATGGCTCTCAACGCTAGACCTCAGAGCCCACGAGAAGGGCATAT
GATGGATGCTTTGTATGCCCAAGTCAAGAAGCCGCGGAATTCCAAACCCTCACCTGTAGACAGTAACAGATCAACTCCTAGCAATCATGA
TCGGATACAGCGTCTGAGGCAAGAATTTCAGCAAGCAAAGCAAGATGAAGATGTAGAAGATCGTCGGCGGACCTATAGTTTTGAGCAACC
CTGGCCGAACGCACGGCCGGCGACGCAGAGCGGGCGACACTCGGTGTCCGTGGAGGTGCAGATGCAGCGGCAGCGGCAGGAGGAGCGCGA
GAGCTCCCAGCAGGCCCAGCGCCAGTACAGCTCTCTGCCTCGGCAAAGCAGGAAAAATGCCAGCTCGGTCTCCCAGGACTCTTGGGAGCA
GAACTACTCCCCTGGGGAAGGCTTCCAGAGTGCCAAAGAGAACCCCAGGTACTCCAGCTACCAAGGCTCCAGGAACGGCTACCTGGGAGG
ACATGGCTTCAACGCCAGGGTCATGCTGGAAACTCAGGAGCTCCTTCGCCAGGAACAGAGGCGGAAGGAGCAGCAGATGAAGAAGCAGCC
TCCTTCCGAGGGGCCCAGCAACTATGACTCGTATAAGAAAGTCCAGGACCCCAGTTACGCCCCTCCCAAGGGGCCCTTCCGGCAAGATGT
GCCCCCCTCCCCTTCTCAGGTTGCGAGGCTGAACAGACTTCAGACTCCTGAGAAAGGGAGGCCCTTCTATTCCTGAGCACGCAAATAACG
GATGCTTCATGTCGCGCAATAAAAGACATTTTCCTATGAAGACTTGTATTTTGGGAGTTTTTTTAAAACCTCGATGGTACTATGGAGTAT
TTCTGTTGTTGGTATCAGTGCCTTTAAGCGGTGTAGGCAAAGAAATGGAAGGCCTTAATGTCTTTGCCACTATGTCTCAAGTGTCTGTTT
CATGGAAGGATTTCCCACCCTGTGACAATCATCTGTTTGAGGTGTTCATATGCTCTGCGCCTCTCCACAGTACCAGGAATCTCGGCCCTA
CTCATGAGTTGTCCGCGGCTTGGTTGTAACATCCCTGCACCACTTGCAGTGACAAATTCACCTGAAGTGGAGGATGACGTGCGGCCCTGT
TTCTCCCTCTAAGTTCTCTTAGCTATGGGATGACATCTTAGTCTCTGGTGGAGGAAAAGTGGGCGACATACACCAAAAATTGGGGCTTTC
TGGTACTTCACAGCACAGCCATTTGTCGTACTTTGTCATCACTGTGGTTTTCTCTTTCCTTTCTCAGCTCTTTGTGACGGGAGAGTCGGT
CATCCTATTACAGAAGCTAAGCCATAGTCCAACATTGTTTGGTCACCATGGGGGTCCTTTTGTAACTGCCTTATGACTCAACATTACCAA
TAAAGTGATGATCCTGGTCTGCGTTTATACATACGCTTGTTCGGTCCTGTTCCTGACACGTGGGTTGAGTCACCACAGCTCTGTGTGGGG
AACGTGGGAGACAGGAGTGGCTCCTGCCGGGGGAAGCTGGGCCTGCCATTGGCCCTGTGTCTATCATGAGGGGAGAGCTAAGAAAGAAAT
TCTCCTAGGAAGAGCTCATGGCCCAGTACATCCTAGTAATTATTTTAATTAGTTTTTGTTCTGACAGCTTGTCAGGAAGGGCACAGAATG
GGACAGAGATAAACCAGACAGTCATTTTGATCTGCTCTCTACGGTTTTTCAAGTCAGAGGCAATTGATGCTTGTCTAATGCATCCACACA
CTGCATGTCTGACTGGCGATGCCGCGCTCCTAAGTAGTTCTGCCATGAAACATAAAAGACAAAGGAAAAGCCGTTACACATCACACAGAG
AACATTTTCGGGTCCCACAGCGGTGGTGGCAGGAAGCTCACTCTCGCGTCAGTATTAGAGTGTGTGTGTGGGTCTCGGGGATCTCGGTGG
CTCCCATCTTCCTTCATTGTTCTGAACATCCTGTATTGTAAACCATGGCTGGGGTGCTAAAGTGCCTGTGAATCCCGATGTGGAAAAAGC
TGGAGGTGAAAGCTCAGCATACCATGTATTTACTTTAAAAACAGAAAAAAAGACATGTATGGATATGTCTATTTTTTTTTTATTGGCACA
TTGTATTTTTGTGTTGACTTGTTTTTAGAAATGATGTGTCCACACACGTACCCGTGTCTCTTCTGCATTTCTGTGTCATGGTTCTGTTTC
TTAATCACGTGCGGCGGTGTCTAAGTGGTGTTACCAGTGTACGCGCAGTGACCTTGGATGACAGTGGCTCTTTCTCACAGCCTCCCCTGA

>20659_20659_3_CUL2-PARD3_CUL2_chr10_35333494_ENST00000374746_PARD3_chr10_34806087_ENST00000374788_length(amino acids)=1517AA_BP=0
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVRHLHKRVLESEEQVLVMYHRY
WEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQAILIRMLLREIKNDRGGEDPNQKV
IHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYMEKLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGS
ELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKD
ENYRSLPRDTSNWSNQFQRDNARSSLSASHPMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGI
HVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNN
YYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKK
GTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPREL
NAEPSQMQIPKETKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVN
GESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALS
RIMGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMS
EKRTKQFSDASQLDFVKTRKSKSMDLGIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGR
GCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDK
MKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYG
GVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRRTYSFEQPWPNARPA
TQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSPGEGFQSAKENPRYSSYQGSRNGYLGGHGFNARV

--------------------------------------------------------------
>20659_20659_4_CUL2-PARD3_CUL2_chr10_35333494_ENST00000374746_PARD3_chr10_34806087_ENST00000374789_length(transcript)=6193nt_BP=736nt
ATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACAATAAAAGC
CGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCTGAACCCCT
TGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAAGAACAAGT
ACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACCCAGTTTAT
TAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGAGAGCTAGC
ATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGATCGTGGTGG
AGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTAAAGTTTTA
TCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCAAACTGCTC
ACAGTATATGGAAAAGCTGGTAGCAGTGTTTGATGAGCAGGATCCACATCACGGAGGTGATGGCACCAGTGCCAGTTCCACGGGTACCCA
GAGCCCAGAGATATTTGGTAGTGAGCTTGGCACCAACAATGTCTCAGCCTTTCAGCCTTACCAAGCAACAAGTGAAATTGAGGTCACACC
TTCAGTCCTTCGAGCAAATATGCCTCTTCATGTTCGACGCAGTAGTGACCCAGCTCTAATTGGCCTCTCCACTTCTGTCAGTGATAGTAA
TTTTTCCTCTGAAGAGCCTTCAAGGAAAAATCCCACACGCTGGTCAACAACAGCTGGCTTCCTCAAGCAGAACACTGCTGGGAGTCCTAA
AACCTGCGACAGGAAGAAAGATGAAAACTACAGAAGCCTCCCGCGGGATACTAGTAACTGGTCTAACCAATTTCAGAGAGACAATGCTCG
CTCGTCTCTGAGTGCCAGTCACCCAATGGTGGGCAAGTGGCTGGAGAAACAAGAACAGGATGAGGATGGGACAGAAGAGGATAACAGTCG
TGTTGAACCTGTTGGACATGCTGACACGGGTTTGGAGCATATACCCAACTTTTCTCTGGATGATATGGTAAAGCTCGTAGAAGTCCCCAA
CGATGGAGGGCCTCTGGGAATCCACGTAGTGCCTTTCAGTGCTCGAGGCGGCAGAACCCTGGGGTTATTAGTAAAACGATTGGAGAAAGG
TGGTAAAGCTGAACATGAAAATCTTTTTCGTGAGAATGATTGCATTGTCAGGATTAATGATGGCGACCTTCGAAATAGAAGATTTGAACA
AGCACAACATATGTTTCGCCAAGCCATGCGTACACCCATCATTTGGTTCCATGTGGTTCCTGCAGCAAATAAAGAGCAGTATGAACAACT
ATCCCAAAGTGAGAAGAACAATTACTATTCAAGCCGTTTTAGCCCTGACAGCCAGTATATTGACAACAGGAGTGTGAACAGTGCAGGGCT
TCACACGGTGCAGAGAGCACCCCGACTGAACCACCCGCCTGAGCAGATAGACTCTCACTCAAGACTACCTCATAGCGCACACCCCTCGGG
AAAACCACCATCCGCTCCAGCCTCGGCACCTCAGAATGTATTTAGTACGACTGTAAGCAGTGGTTATAACACCAAAAAAATAGGCAAGAG
GCTTAATATCCAGCTTAAGAAAGGTACAGAAGGTTTGGGATTCAGCATCACTTCCAGAGATGTAACAATAGGTGGCTCAGCTCCAATCTA
TGTGAAAAACATTCTCCCCCGGGGGGCGGCCATTCAGGATGGCCGACTTAAGGCAGGAGACAGACTTATAGAGGTAAATGGAGTAGATTT
AGTGGGCAAATCCCAAGAGGAAGTTGTTTCGCTGTTGAGAAGCACCAAGATGGAAGGAACTGTGAGCCTTCTGGTCTTTCGCCAGGAAGA
CGCCTTCCACCCAAGGGAACTGAATGCAGAGCCAAGCCAGATGCAGATTCCAAAAGAAACGAAAGCAGAAGATGAGGATATTGTTCTTAC
ACCTGATGGCACCAGGGAATTTCTGACATTTGAAGTCCCACTTAATGATTCAGGATCTGCAGGCCTTGGTGTCAGTGTCAAAGGTAACCG
GTCAAAAGAGAACCACGCAGATTTGGGAATCTTTGTCAAGTCCATTATTAATGGAGGAGCAGCATCTAAAGATGGAAGGCTTCGGGTGAA
TGATCAACTGATAGCAGTAAATGGAGAATCCCTGTTGGGCAAGACAAACCAAGATGCCATGGAAACCCTAAGAAGGTCTATGTCTACTGA
AGGCAATAAACGAGGAATGATCCAGCTTATTGTTGCAAGGAGAATAAGCAAGTGCAATGAGCTGAAGTCACCTGGGAGCCCCCCTGGACC
TGAGCTGCCCATTGAAACAGCGTTGGATGATAGAGAACGAAGAATTTCCCATTCCCTCTACAGTGGGATTGAGGGGCTTGATGAATCGCC
CAGCAGAAATGCTGCCCTCAGTAGGATAATGGGTGAGTCAGGTAAATACCAGCTGTCCCCTACAGTGAATATGCCCCAAGATGACACTGT
CATTATAGAAGATGACAGGTTGCCAGTGCTTCCTCCACATCTCTCTGACCAGTCCTCTTCCAGCTCCCATGATGATGTGGGGTTTGTGAC
GGCAGATGCTGGTACTTGGGCCAAGGCTGCAATCAGTGATTCAGCCGACTGCTCTTTGAGTCCAGATGTTGATCCAGTTCTTGCTTTTCA
ACGAGAAGGATTTGGACGTCAGAGTATGTCAGAAAAACGCACAAAGCAATTTTCAGATGCCAGTCAATTGGATTTCGTTAAAACACGAAA
ATCAAAAAGCATGGATTTAGGTATAGCTGACGAGACTAAACTCAATACAGTGGATGACCAGAAAGCAGGTTCTCCCAGCAGAGATGTGGG
TCCTTCCCTGGGTCTGAAGAAGTCAAGCTCGTTGGAGAGTCTGCAGACCGCAGTTGCCGAGGTGACTTTGAATGGGGATATTCCTTTCCA
TCGTCCACGGCCGCGGATAATCAGAGGCAGGGGATGCAATGAGAGCTTCAGAGCTGCCATCGACAAATCTTATGATAAACCCGCGGTAGA
TGATGATGATGAAGGCATGGAGACCTTGGAAGAAGACACAGAAGAAAGTTCAAGATCAGGGAGAGAGTCTGTATCCACAGCCAGTGATCA
GCCTTCCCACTCTCTGGAGAGACAAATGAATGGAAACCAAGAGAAAGGTGATAAGACTGATAGAAAAAAGGATAAAACTGGAAAAGAAAA
GAAGAAAGATAGAGATAAGGAGAAGGATAAAATGAAAGCCAAGAAGGGAATGCTGAAGGGCTTGGGAGACATGTTCAGGTTTGGCAAACA
TCGAAAAGATGACAAGATTGAGAAAACGGGTAAAATAAAAATACAGGAATCCTTTACATCAGAAGAGGAGAGGATACGAATGAAGCAGGA
GCAGGAGAGGATTCAAGCCAAAACTCGAGAATTTAGGGAACGACAAGCTCGAGAGCGTGACTATGCTGAAATTCAAGATTTTCATCGGAC
ATTTGGCTGTGATGATGAGTTAATGTATGGGGGAGTTTCTTCTTATGAAGGTTCCATGGCTCTCAACGCTAGACCTCAGAGCCCACGAGA
AGGGCATATGATGGATGCTTTGTATGCCCAAGTCAAGAAGCCGCGGAATTCCAAACCCTCACCTGTAGACAGTAACAGATCAACTCCTAG
CAATCATGATCGGATACAGCGTCTGAGGCAAGAATTTCAGCAAGCAAAGCAAGATGAAGATGTAGAAGATCGTCGGCGGACCTATAGTTT
TGAGCAACCCTGGCCGAACGCACGGCCGGCGACGCAGAGCGGGCGACACTCGGTGTCCGTGGAGGTGCAGATGCAGCGGCAGCGGCAGGA
GGAGCGCGAGAGCTCCCAGCAGGCCCAGCGCCAGTACAGCTCTCTGCCTCGGCAAAGCAGGAAAAATGCCAGCTCGGTCTCCCAGGACTC
TTGGGAGCAGAACTACTCCCCTGGGGAAGGCTTCCAGAGTGCCAAAGAGAACCCCAGGTACTCCAGCTACCAAGGCTCCAGGAACGGCTA
CCTGGGAGGACATGGCTTCAACGCCAGGGTCATGCTGGAAACTCAGGAGCTCCTTCGCCAGGAACAGAGGCGGAAGGAGCAGCAGATGAA
GAAGCAGCCTCCTTCCGAGGGGCCCAGCAACTATGACTCGTATAAGAAAGTCCAGGACCCCAGTTACGCCCCTCCCAAGGGGCCCTTCCG
GCAAGATGTGCCCCCCTCCCCTTCTCAGGTTGCGAGGCTGAACAGACTTCAGACTCCTGAGAAAGGGAGGCCCTTCTATTCCTGAGCACG
CAAATAACGGATGCTTCATGTCGCGCAATAAAAGACATTTTCCTATGAAGACTTGTATTTTGGGAGTTTTTTTAAAACCTCGATGGTACT
ATGGAGTATTTCTGTTGTTGGTATCAGTGCCTTTAAGCGGTGTAGGCAAAGAAATGGAAGGCCTTAATGTCTTTGCCACTATGTCTCAAG
TGTCTGTTTCATGGAAGGATTTCCCACCCTGTGACAATCATCTGTTTGAGGTGTTCATATGCTCTGCGCCTCTCCACAGTACCAGGAATC
TCGGCCCTACTCATGAGTTGTCCGCGGCTTGGTTGTAACATCCCTGCACCACTTGCAGTGACAAATTCACCTGAAGTGGAGGATGACGTG
CGGCCCTGTTTCTCCCTCTAAGTTCTCTTAGCTATGGGATGACATCTTAGTCTCTGGTGGAGGAAAAGTGGGCGACATACACCAAAAATT
GGGGCTTTCTGGTACTTCACAGCACAGCCATTTGTCGTACTTTGTCATCACTGTGGTTTTCTCTTTCCTTTCTCAGCTCTTTGTGACGGG
AGAGTCGGTCATCCTATTACAGAAGCTAAGCCATAGTCCAACATTGTTTGGTCACCATGGGGGTCCTTTTGTAACTGCCTTATGACTCAA
CATTACCAATAAAGTGATGATCCTGGTCTGCGTTTATACATACGCTTGTTCGGTCCTGTTCCTGACACGTGGGTTGAGTCACCACAGCTC
TGTGTGGGGAACGTGGGAGACAGGAGTGGCTCCTGCCGGGGGAAGCTGGGCCTGCCATTGGCCCTGTGTCTATCATGAGGGGAGAGCTAA
GAAAGAAATTCTCCTAGGAAGAGCTCATGGCCCAGTACATCCTAGTAATTATTTTAATTAGTTTTTGTTCTGACAGCTTGTCAGGAAGGG
CACAGAATGGGACAGAGATAAACCAGACAGTCATTTTGATCTGCTCTCTACGGTTTTTCAAGTCAGAGGCAATTGATGCTTGTCTAATGC
ATCCACACACTGCATGTCTGACTGGCGATGCCGCGCTCCTAAGTAGTTCTGCCATGAAACATAAAAGACAAAGGAAAAGCCGTTACACAT
CACACAGAGAACATTTTCGGGTCCCACAGCGGTGGTGGCAGGAAGCTCACTCTCGCGTCAGTATTAGAGTGTGTGTGTGGGTCTCGGGGA
TCTCGGTGGCTCCCATCTTCCTTCATTGTTCTGAACATCCTGTATTGTAAACCATGGCTGGGGTGCTAAAGTGCCTGTGAATCCCGATGT
GGAAAAAGCTGGAGGTGAAAGCTCAGCATACCATGTATTTACTTTAAAAACAGAAAAAAAGACATGTATGGATATGTCTATTTTTTTTTT
ATTGGCACATTGTATTTTTGTGTTGACTTGTTTTTAGAAATGATGTGTCCACACACGTACCCGTGTCTCTTCTGCATTTCTGTGTCATGG
TTCTGTTTCTTAATCACGTGCGGCGGTGTCTAAGTGGTGTTACCAGTGTACGCGCAGTGACCTTGGATGACAGTGGCTCTTTCTCACAGC

>20659_20659_4_CUL2-PARD3_CUL2_chr10_35333494_ENST00000374746_PARD3_chr10_34806087_ENST00000374789_length(amino acids)=1520AA_BP=0
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVRHLHKRVLESEEQVLVMYHRY
WEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQAILIRMLLREIKNDRGGEDPNQKV
IHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYMEKLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGS
ELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKD
ENYRSLPRDTSNWSNQFQRDNARSSLSASHPMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGI
HVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNN
YYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKK
GTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPREL
NAEPSQMQIPKETKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVN
GESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALS
RIMGESGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQ
SMSEKRTKQFSDASQLDFVKTRKSKSMDLGIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRII
RGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKE
KDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDEL
MYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRRTYSFEQPWPNA
RPATQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSPGEGFQSAKENPRYSSYQGSRNGYLGGHGFN

--------------------------------------------------------------
>20659_20659_5_CUL2-PARD3_CUL2_chr10_35333494_ENST00000374746_PARD3_chr10_34806087_ENST00000374790_length(transcript)=6013nt_BP=736nt
ATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACAATAAAAGC
CGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCTGAACCCCT
TGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAAGAACAAGT
ACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACCCAGTTTAT
TAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGAGAGCTAGC
ATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGATCGTGGTGG
AGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTAAAGTTTTA
TCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCAAACTGCTC
ACAGTATATGGAAAAGCTGGTAGCAGTGTTTGATGAGCAGGATCCACATCACGGAGGTGATGGCACCAGTGCCAGTTCCACGGGTACCCA
GAGCCCAGAGATATTTGGTAGTGAGCTTGGCACCAACAATGTCTCAGCCTTTCAGCCTTACCAAGCAACAAGTGAAATTGAGGTCACACC
TTCAGTCCTTCGAGCAAATATGCCTCTTCATGTTCGACGCAGTAGTGACCCAGCTCTAATTGGCCTCTCCACTTCTGTCAGTGATAGTAA
TTTTTCCTCTGAAGAGCCTTCAAGGAAAAATCCCACACGCTGGTCAACAACAGCTGGCTTCCTCAAGCAGAACACTGCTGGGAGTCCTAA
AACCTGCGACAGGAAGGATGAGGATGGGACAGAAGAGGATAACAGTCGTGTTGAACCTGTTGGACATGCTGACACGGGTTTGGAGCATAT
ACCCAACTTTTCTCTGGATGATATGGTAAAGCTCGTAGAAGTCCCCAACGATGGAGGGCCTCTGGGAATCCACGTAGTGCCTTTCAGTGC
TCGAGGCGGCAGAACCCTGGGGTTATTAGTAAAACGATTGGAGAAAGGTGGTAAAGCTGAACATGAAAATCTTTTTCGTGAGAATGATTG
CATTGTCAGGATTAATGATGGCGACCTTCGAAATAGAAGATTTGAACAAGCACAACATATGTTTCGCCAAGCCATGCGTACACCCATCAT
TTGGTTCCATGTGGTTCCTGCAGCAAATAAAGAGCAGTATGAACAACTATCCCAAAGTGAGAAGAACAATTACTATTCAAGCCGTTTTAG
CCCTGACAGCCAGTATATTGACAACAGGAGTGTGAACAGTGCAGGGCTTCACACGGTGCAGAGAGCACCCCGACTGAACCACCCGCCTGA
GCAGATAGACTCTCACTCAAGACTACCTCATAGCGCACACCCCTCGGGAAAACCACCATCCGCTCCAGCCTCGGCACCTCAGAATGTATT
TAGTACGACTGTAAGCAGTGGTTATAACACCAAAAAAATAGGCAAGAGGCTTAATATCCAGCTTAAGAAAGGTACAGAAGGTTTGGGATT
CAGCATCACTTCCAGAGATGTAACAATAGGTGGCTCAGCTCCAATCTATGTGAAAAACATTCTCCCCCGGGGGGCGGCCATTCAGGATGG
CCGACTTAAGGCAGGAGACAGACTTATAGAGGTAAATGGAGTAGATTTAGTGGGCAAATCCCAAGAGGAAGTTGTTTCGCTGTTGAGAAG
CACCAAGATGGAAGGAACTGTGAGCCTTCTGGTCTTTCGCCAGGAAGACGCCTTCCACCCAAGGGAACTGAAAGCAGAAGATGAGGATAT
TGTTCTTACACCTGATGGCACCAGGGAATTTCTGACATTTGAAGTCCCACTTAATGATTCAGGATCTGCAGGCCTTGGTGTCAGTGTCAA
AGGTAACCGGTCAAAAGAGAACCACGCAGATTTGGGAATCTTTGTCAAGTCCATTATTAATGGAGGAGCAGCATCTAAAGATGGAAGGCT
TCGGGTGAATGATCAACTGATAGCAGTAAATGGAGAATCCCTGTTGGGCAAGACAAACCAAGATGCCATGGAAACCCTAAGAAGGTCTAT
GTCTACTGAAGGCAATAAACGAGGAATGATCCAGCTTATTGTTGCAAGGAGAATAAGCAAGTGCAATGAGCTGAAGTCACCTGGGAGCCC
CCCTGGACCTGAGCTGCCCATTGAAACAGCGTTGGATGATAGAGAACGAAGAATTTCCCATTCCCTCTACAGTGGGATTGAGGGGCTTGA
TGAATCGCCCAGCAGAAATGCTGCCCTCAGTAGGATAATGGGTAAATACCAGCTGTCCCCTACAGTGAATATGCCCCAAGATGACACTGT
CATTATAGAAGATGACAGGTTGCCAGTGCTTCCTCCACATCTCTCTGACCAGTCCTCTTCCAGCTCCCATGATGATGTGGGGTTTGTGAC
GGCAGATGCTGGTACTTGGGCCAAGGCTGCAATCAGTGATTCAGCCGACTGCTCTTTGAGTCCAGATGTTGATCCAGTTCTTGCTTTTCA
ACGAGAAGGATTTGGACGTCAGAGTATGTCAGAAAAACGCACAAAGCAATTTTCAGATGCCAGTCAATTGGATTTCGTTAAAACACGAAA
ATCAAAAAGCATGGATTTAGGTATAGCTGACGAGACTAAACTCAATACAGTGGATGACCAGAAAGCAGGTTCTCCCAGCAGAGATGTGGG
TCCTTCCCTGGGTCTGAAGAAGTCAAGCTCGTTGGAGAGTCTGCAGACCGCAGTTGCCGAGGTGACTTTGAATGGGGATATTCCTTTCCA
TCGTCCACGGCCGCGGATAATCAGAGGCAGGGGATGCAATGAGAGCTTCAGAGCTGCCATCGACAAATCTTATGATAAACCCGCGGTAGA
TGATGATGATGAAGGCATGGAGACCTTGGAAGAAGACACAGAAGAAAGTTCAAGATCAGGGAGAGAGTCTGTATCCACAGCCAGTGATCA
GCCTTCCCACTCTCTGGAGAGACAAATGAATGGAAACCAAGAGAAAGGTGATAAGACTGATAGAAAAAAGGATAAAACTGGAAAAGAAAA
GAAGAAAGATAGAGATAAGGAGAAGGATAAAATGAAAGCCAAGAAGGGAATGCTGAAGGGCTTGGGAGACATGTTCAGGTTTGGCAAACA
TCGAAAAGATGACAAGATTGAGAAAACGGGTAAAATAAAAATACAGGAATCCTTTACATCAGAAGAGGAGAGGATACGAATGAAGCAGGA
GCAGGAGAGGATTCAAGCCAAAACTCGAGAATTTAGGGAACGACAAGCTCGAGAGCGTGACTATGCTGAAATTCAAGATTTTCATCGGAC
ATTTGGCTGTGATGATGAGTTAATGTATGGGGGAGTTTCTTCTTATGAAGGTTCCATGGCTCTCAACGCTAGACCTCAGAGCCCACGAGA
AGGGCATATGATGGATGCTTTGTATGCCCAAGTCAAGAAGCCGCGGAATTCCAAACCCTCACCTGTAGACAGTAACAGATCAACTCCTAG
CAATCATGATCGGATACAGCGTCTGAGGCAAGAATTTCAGCAAGCAAAGCAAGATGAAGATGTAGAAGATCGTCGGCGGACCTATAGTTT
TGAGCAACCCTGGCCGAACGCACGGCCGGCGACGCAGAGCGGGCGACACTCGGTGTCCGTGGAGGTGCAGATGCAGCGGCAGCGGCAGGA
GGAGCGCGAGAGCTCCCAGCAGGCCCAGCGCCAGTACAGCTCTCTGCCTCGGCAAAGCAGGAAAAATGCCAGCTCGGTCTCCCAGGACTC
TTGGGAGCAGAACTACTCCCCTGGGGAAGGCTTCCAGAGTGCCAAAGAGAACCCCAGGTACTCCAGCTACCAAGGCTCCAGGAACGGCTA
CCTGGGAGGACATGGCTTCAACGCCAGGGTCATGCTGGAAACTCAGGAGCTCCTTCGCCAGGAACAGAGGCGGAAGGAGCAGCAGATGAA
GAAGCAGCCTCCTTCCGAGGGGCCCAGCAACTATGACTCGTATAAGAAAGTCCAGGACCCCAGTTACGCCCCTCCCAAGGGGCCCTTCCG
GCAAGATGTGCCCCCCTCCCCTTCTCAGGTTGCGAGGCTGAACAGACTTCAGACTCCTGAGAAAGGGAGGCCCTTCTATTCCTGAGCACG
CAAATAACGGATGCTTCATGTCGCGCAATAAAAGACATTTTCCTATGAAGACTTGTATTTTGGGAGTTTTTTTAAAACCTCGATGGTACT
ATGGAGTATTTCTGTTGTTGGTATCAGTGCCTTTAAGCGGTGTAGGCAAAGAAATGGAAGGCCTTAATGTCTTTGCCACTATGTCTCAAG
TGTCTGTTTCATGGAAGGATTTCCCACCCTGTGACAATCATCTGTTTGAGGTGTTCATATGCTCTGCGCCTCTCCACAGTACCAGGAATC
TCGGCCCTACTCATGAGTTGTCCGCGGCTTGGTTGTAACATCCCTGCACCACTTGCAGTGACAAATTCACCTGAAGTGGAGGATGACGTG
CGGCCCTGTTTCTCCCTCTAAGTTCTCTTAGCTATGGGATGACATCTTAGTCTCTGGTGGAGGAAAAGTGGGCGACATACACCAAAAATT
GGGGCTTTCTGGTACTTCACAGCACAGCCATTTGTCGTACTTTGTCATCACTGTGGTTTTCTCTTTCCTTTCTCAGCTCTTTGTGACGGG
AGAGTCGGTCATCCTATTACAGAAGCTAAGCCATAGTCCAACATTGTTTGGTCACCATGGGGGTCCTTTTGTAACTGCCTTATGACTCAA
CATTACCAATAAAGTGATGATCCTGGTCTGCGTTTATACATACGCTTGTTCGGTCCTGTTCCTGACACGTGGGTTGAGTCACCACAGCTC
TGTGTGGGGAACGTGGGAGACAGGAGTGGCTCCTGCCGGGGGAAGCTGGGCCTGCCATTGGCCCTGTGTCTATCATGAGGGGAGAGCTAA
GAAAGAAATTCTCCTAGGAAGAGCTCATGGCCCAGTACATCCTAGTAATTATTTTAATTAGTTTTTGTTCTGACAGCTTGTCAGGAAGGG
CACAGAATGGGACAGAGATAAACCAGACAGTCATTTTGATCTGCTCTCTACGGTTTTTCAAGTCAGAGGCAATTGATGCTTGTCTAATGC
ATCCACACACTGCATGTCTGACTGGCGATGCCGCGCTCCTAAGTAGTTCTGCCATGAAACATAAAAGACAAAGGAAAAGCCGTTACACAT
CACACAGAGAACATTTTCGGGTCCCACAGCGGTGGTGGCAGGAAGCTCACTCTCGCGTCAGTATTAGAGTGTGTGTGTGGGTCTCGGGGA
TCTCGGTGGCTCCCATCTTCCTTCATTGTTCTGAACATCCTGTATTGTAAACCATGGCTGGGGTGCTAAAGTGCCTGTGAATCCCGATGT
GGAAAAAGCTGGAGGTGAAAGCTCAGCATACCATGTATTTACTTTAAAAACAGAAAAAAAGACATGTATGGATATGTCTATTTTTTTTTT
ATTGGCACATTGTATTTTTGTGTTGACTTGTTTTTAGAAATGATGTGTCCACACACGTACCCGTGTCTCTTCTGCATTTCTGTGTCATGG
TTCTGTTTCTTAATCACGTGCGGCGGTGTCTAAGTGGTGTTACCAGTGTACGCGCAGTGACCTTGGATGACAGTGGCTCTTTCTCACAGC

>20659_20659_5_CUL2-PARD3_CUL2_chr10_35333494_ENST00000374746_PARD3_chr10_34806087_ENST00000374790_length(amino acids)=1460AA_BP=0
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVRHLHKRVLESEEQVLVMYHRY
WEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQAILIRMLLREIKNDRGGEDPNQKV
IHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYMEKLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGS
ELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKDE
DGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDG
DLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSR
LPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDR
LIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKEN
HADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPI
ETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWA
KAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLGIADETKLNTVDDQKAGSPSRDVGPSLGLKK
SSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLER
QMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAK
TREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQR
LRQEFQQAKQDEDVEDRRRTYSFEQPWPNARPATQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSP
GEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVMLETQELLRQEQRRKEQQMKKQPPSEGPSNYDSYKKVQDPSYAPPKGPFRQDVPPSP

--------------------------------------------------------------
>20659_20659_6_CUL2-PARD3_CUL2_chr10_35333494_ENST00000374746_PARD3_chr10_34806087_ENST00000374794_length(transcript)=5857nt_BP=736nt
ATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACAATAAAAGC
CGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCTGAACCCCT
TGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAAGAACAAGT
ACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACCCAGTTTAT
TAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGAGAGCTAGC
ATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGATCGTGGTGG
AGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTAAAGTTTTA
TCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCAAACTGCTC
ACAGTATATGGAAAAGCTGGTAGCAGTGTTTGATGAGCAGGATCCACATCACGGAGGTGATGGCACCAGTGCCAGTTCCACGGGTACCCA
GAGCCCAGAGATATTTGGTAGTGAGCTTGGCACCAACAATGTCTCAGCCTTTCAGCCTTACCAAGCAACAAGTGAAATTGAGGTCACACC
TTCAGTCCTTCGAGCAAATATGCCTCTTCATGTTCGACGCAGTAGTGACCCAGCTCTAATTGGCCTCTCCACTTCTGTCAGTGATAGTAA
TTTTTCCTCTGAAGAGCCTTCAAGGAAAAATCCCACACGCTGGTCAACAACAGCTGGCTTCCTCAAGCAGAACACTGCTGGGAGTCCTAA
AACCTGCGACAGGAAGGATGAGGATGGGACAGAAGAGGATAACAGTCGTGTTGAACCTGTTGGACATGCTGACACGGGTTTGGAGCATAT
ACCCAACTTTTCTCTGGATGATATGGTAAAGCTCGTAGAAGTCCCCAACGATGGAGGGCCTCTGGGAATCCACGTAGTGCCTTTCAGTGC
TCGAGGCGGCAGAACCCTGGGGTTATTAGTAAAACGATTGGAGAAAGGTGGTAAAGCTGAACATGAAAATCTTTTTCGTGAGAATGATTG
CATTGTCAGGATTAATGATGGCGACCTTCGAAATAGAAGATTTGAACAAGCACAACATATGTTTCGCCAAGCCATGCGTACACCCATCAT
TTGGTTCCATGTGGTTCCTGCAGCAAATAAAGAGCAGTATGAACAACTATCCCAAAGTGAGAAGAACAATTACTATTCAAGCCGTTTTAG
CCCTGACAGCCAGTATATTGACAACAGGAGTGTGAACAGTGCAGGGCTTCACACGGTGCAGAGAGCACCCCGACTGAACCACCCGCCTGA
GCAGATAGACTCTCACTCAAGACTACCTCATAGCGCACACCCCTCGGGAAAACCACCATCCGCTCCAGCCTCGGCACCTCAGAATGTATT
TAGTACGACTGTAAGCAGTGGTTATAACACCAAAAAAATAGGCAAGAGGCTTAATATCCAGCTTAAGAAAGGTACAGAAGGTTTGGGATT
CAGCATCACTTCCAGAGATGTAACAATAGGTGGCTCAGCTCCAATCTATGTGAAAAACATTCTCCCCCGGGGGGCGGCCATTCAGGATGG
CCGACTTAAGGCAGGAGACAGACTTATAGAGGTAAATGGAGTAGATTTAGTGGGCAAATCCCAAGAGGAAGTTGTTTCGCTGTTGAGAAG
CACCAAGATGGAAGGAACTGTGAGCCTTCTGGTCTTTCGCCAGGAAGACGCCTTCCACCCAAGGGAACTGAAAGCAGAAGATGAGGATAT
TGTTCTTACACCTGATGGCACCAGGGAATTTCTGACATTTGAAGTCCCACTTAATGATTCAGGATCTGCAGGCCTTGGTGTCAGTGTCAA
AGGTAACCGGTCAAAAGAGAACCACGCAGATTTGGGAATCTTTGTCAAGTCCATTATTAATGGAGGAGCAGCATCTAAAGATGGAAGGCT
TCGGGTGAATGATCAACTGATAGCAGTAAATGGAGAATCCCTGTTGGGCAAGACAAACCAAGATGCCATGGAAACCCTAAGAAGGTCTAT
GTCTACTGAAGGCAATAAACGAGGAATGATCCAGCTTATTGTTGCAAGGAGAATAAGCAAGTGCAATGAGCTGAAGTCACCTGGGAGCCC
CCCTGGACCTGAGCTGCCCATTGAAACAGCGTTGGATGATAGAGAACGAAGAATTTCCCATTCCCTCTACAGTGGGATTGAGGGGCTTGA
TGAATCGCCCAGCAGAAATGCTGCCCTCAGTAGGATAATGGGTAAATACCAGCTGTCCCCTACAGTGAATATGCCCCAAGATGACACTGT
CATTATAGAAGATGACAGGTTGCCAGTGCTTCCTCCACATCTCTCTGACCAGTCCTCTTCCAGCTCCCATGATGATGTGGGGTTTGTGAC
GGCAGATGCTGGTACTTGGGCCAAGGCTGCAATCAGTGATTCAGCCGACTGCTCTTTGAGTCCAGATGTTGATCCAGTTCTTGCTTTTCA
ACGAGAAGGATTTGGACGTCAGAGTATGTCAGAAAAACGCACAAAGCAATTTTCAGATGCCAGTCAATTGGATTTCGTTAAAACACGAAA
ATCAAAAAGCATGGATTTAGGTAGTTCTCCCAGCAGAGATGTGGGTCCTTCCCTGGGTCTGAAGAAGTCAAGCTCGTTGGAGAGTCTGCA
GACCGCAGTTGCCGAGGTGACTTTGAATGGGGATATTCCTTTCCATCGTCCACGGCCGCGGATAATCAGAGGCAGGGGATGCAATGAGAG
CTTCAGAGCTGCCATCGACAAATCTTATGATAAACCCGCGGTAGATGATGATGATGAAGGCATGGAGACCTTGGAAGAAGACACAGAAGA
AAGTTCAAGATCAGGGAGAGAGTCTGTATCCACAGCCAGTGATCAGCCTTCCCACTCTCTGGAGAGACAAATGAATGGAAACCAAGAGAA
AGGTGATAAGACTGATAGAAAAAAGGATAAAACTGGAAAAGAAAAGAAGAAAGATAGAGATAAGGAGAAGGATAAAATGAAAGCCAAGAA
GGGAATGCTGAAGGGCTTGGGAGACATGTTCAGGATTCAAGCCAAAACTCGAGAATTTAGGGAACGACAAGCTCGAGAGCGTGACTATGC
TGAAATTCAAGATTTTCATCGGACATTTGGCTGTGATGATGAGTTAATGTATGGGGGAGTTTCTTCTTATGAAGGTTCCATGGCTCTCAA
CGCTAGACCTCAGAGCCCACGAGAAGGGCATATGATGGATGCTTTGTATGCCCAAGTCAAGAAGCCGCGGAATTCCAAACCCTCACCTGT
AGACAGTAACAGATCAACTCCTAGCAATCATGATCGGATACAGCGTCTGAGGCAAGAATTTCAGCAAGCAAAGCAAGATGAAGATGTAGA
AGATCGTCGGCGGACCTATAGTTTTGAGCAACCCTGGCCGAACGCACGGCCGGCGACGCAGAGCGGGCGACACTCGGTGTCCGTGGAGGT
GCAGATGCAGCGGCAGCGGCAGGAGGAGCGCGAGAGCTCCCAGCAGGCCCAGCGCCAGTACAGCTCTCTGCCTCGGCAAAGCAGGAAAAA
TGCCAGCTCGGTCTCCCAGGACTCTTGGGAGCAGAACTACTCCCCTGGGGAAGGCTTCCAGAGTGCCAAAGAGAACCCCAGGTACTCCAG
CTACCAAGGCTCCAGGAACGGCTACCTGGGAGGACATGGCTTCAACGCCAGGGTCATGCTGGAAACTCAGGAGCTCCTTCGCCAGGAACA
GAGGCGGAAGGAGCAGCAGATGAAGAAGCAGCCTCCTTCCGAGGGGCCCAGCAACTATGACTCGTATAAGAAAGTCCAGGACCCCAGTTA
CGCCCCTCCCAAGGGGCCCTTCCGGCAAGATGTGCCCCCCTCCCCTTCTCAGGTTGCGAGGCTGAACAGACTTCAGACTCCTGAGAAAGG
GAGGCCCTTCTATTCCTGAGCACGCAAATAACGGATGCTTCATGTCGCGCAATAAAAGACATTTTCCTATGAAGACTTGTATTTTGGGAG
TTTTTTTAAAACCTCGATGGTACTATGGAGTATTTCTGTTGTTGGTATCAGTGCCTTTAAGCGGTGTAGGCAAAGAAATGGAAGGCCTTA
ATGTCTTTGCCACTATGTCTCAAGTGTCTGTTTCATGGAAGGATTTCCCACCCTGTGACAATCATCTGTTTGAGGTGTTCATATGCTCTG
CGCCTCTCCACAGTACCAGGAATCTCGGCCCTACTCATGAGTTGTCCGCGGCTTGGTTGTAACATCCCTGCACCACTTGCAGTGACAAAT
TCACCTGAAGTGGAGGATGACGTGCGGCCCTGTTTCTCCCTCTAAGTTCTCTTAGCTATGGGATGACATCTTAGTCTCTGGTGGAGGAAA
AGTGGGCGACATACACCAAAAATTGGGGCTTTCTGGTACTTCACAGCACAGCCATTTGTCGTACTTTGTCATCACTGTGGTTTTCTCTTT
CCTTTCTCAGCTCTTTGTGACGGGAGAGTCGGTCATCCTATTACAGAAGCTAAGCCATAGTCCAACATTGTTTGGTCACCATGGGGGTCC
TTTTGTAACTGCCTTATGACTCAACATTACCAATAAAGTGATGATCCTGGTCTGCGTTTATACATACGCTTGTTCGGTCCTGTTCCTGAC
ACGTGGGTTGAGTCACCACAGCTCTGTGTGGGGAACGTGGGAGACAGGAGTGGCTCCTGCCGGGGGAAGCTGGGCCTGCCATTGGCCCTG
TGTCTATCATGAGGGGAGAGCTAAGAAAGAAATTCTCCTAGGAAGAGCTCATGGCCCAGTACATCCTAGTAATTATTTTAATTAGTTTTT
GTTCTGACAGCTTGTCAGGAAGGGCACAGAATGGGACAGAGATAAACCAGACAGTCATTTTGATCTGCTCTCTACGGTTTTTCAAGTCAG
AGGCAATTGATGCTTGTCTAATGCATCCACACACTGCATGTCTGACTGGCGATGCCGCGCTCCTAAGTAGTTCTGCCATGAAACATAAAA
GACAAAGGAAAAGCCGTTACACATCACACAGAGAACATTTTCGGGTCCCACAGCGGTGGTGGCAGGAAGCTCACTCTCGCGTCAGTATTA
GAGTGTGTGTGTGGGTCTCGGGGATCTCGGTGGCTCCCATCTTCCTTCATTGTTCTGAACATCCTGTATTGTAAACCATGGCTGGGGTGC
TAAAGTGCCTGTGAATCCCGATGTGGAAAAAGCTGGAGGTGAAAGCTCAGCATACCATGTATTTACTTTAAAAACAGAAAAAAAGACATG
TATGGATATGTCTATTTTTTTTTTATTGGCACATTGTATTTTTGTGTTGACTTGTTTTTAGAAATGATGTGTCCACACACGTACCCGTGT
CTCTTCTGCATTTCTGTGTCATGGTTCTGTTTCTTAATCACGTGCGGCGGTGTCTAAGTGGTGTTACCAGTGTACGCGCAGTGACCTTGG
ATGACAGTGGCTCTTTCTCACAGCCTCCCCTGAGCTGTGAGAAACAGCTTTCTCTGTACATATGCAACTCCTAATAAAAGGCATATTTCT

>20659_20659_6_CUL2-PARD3_CUL2_chr10_35333494_ENST00000374746_PARD3_chr10_34806087_ENST00000374794_length(amino acids)=1408AA_BP=0
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVRHLHKRVLESEEQVLVMYHRY
WEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQAILIRMLLREIKNDRGGEDPNQKV
IHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYMEKLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGS
ELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKDE
DGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDG
DLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSR
LPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDR
LIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKEN
HADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPI
ETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWA
KAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLGSSPSRDVGPSLGLKKSSSLESLQTAVAEVT
LNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRK
KDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPR
EGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRRTYSFEQPWPNARPATQSGRHSVSVEVQMQRQRQ
EERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSPGEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVMLETQELLRQEQRRKEQQM

--------------------------------------------------------------
>20659_20659_7_CUL2-PARD3_CUL2_chr10_35333494_ENST00000374746_PARD3_chr10_34806087_ENST00000545260_length(transcript)=5924nt_BP=736nt
ATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACAATAAAAGC
CGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCTGAACCCCT
TGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAAGAACAAGT
ACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACCCAGTTTAT
TAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGAGAGCTAGC
ATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGATCGTGGTGG
AGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTAAAGTTTTA
TCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCAAACTGCTC
ACAGTATATGGAAAAGCTGGTAGCAGTGTTTGATGAGCAGGATCCACATCACGGAGGTGATGGCACCAGTGCCAGTTCCACGGGTACCCA
GAGCCCAGAGATATTTGGTAGTGAGCTTGGCACCAACAATGTCTCAGCCTTTCAGCCTTACCAAGCAACAAGTGAAATTGAGGTCACACC
TTCAGTCCTTCGAGCAAATATGCCTCTTCATGTTCGACGCAGTAGTGACCCAGCTCTAATTGGCCTCTCCACTTCTGTCAGTGATAGTAA
TTTTTCCTCTGAAGAGCCTTCAAGGAAAAATCCCACACGCTGGTCAACAACAGCTGGCTTCCTCAAGCAGAACACTGCTGGGAGTCCTAA
AACCTGCGACAGGAAGGATGAGGATGGGACAGAAGAGGATAACAGTCGTGTTGAACCTGTTGGACATGCTGACACGGGTTTGGAGCATAT
ACCCAACTTTTCTCTGGATGATATGGTAAAGCTCGTAGAAGTCCCCAACGATGGAGGGCCTCTGGGAATCCACGTAGTGCCTTTCAGTGC
TCGAGGCGGCAGAACCCTGGGGTTATTAGTAAAACGATTGGAGAAAGGTGGTAAAGCTGAACATGAAAATCTTTTTCGTGAGAATGATTG
CATTGTCAGGATTAATGATGGCGACCTTCGAAATAGAAGATTTGAACAAGCACAACATATGTTTCGCCAAGCCATGCGTACACCCATCAT
TTGGTTCCATGTGGTTCCTGCAGCAAATAAAGAGCAGTATGAACAACTATCCCAAAGTGAGAAGAACAATTACTATTCAAGCCGTTTTAG
CCCTGACAGCCAGTATATTGACAACAGGAGTGTGAACAGTGCAGGGCTTCACACGGTGCAGAGAGCACCCCGACTGAACCACCCGCCTGA
GCAGATAGACTCTCACTCAAGACTACCTCATAGCGCACACCCCTCGGGAAAACCACCATCCGCTCCAGCCTCGGCACCTCAGAATGTATT
TAGTACGACTGTAAGCAGTGGTTATAACACCAAAAAAATAGGCAAGAGGCTTAATATCCAGCTTAAGAAAGGTACAGAAGGTTTGGGATT
CAGCATCACTTCCAGAGATGTAACAATAGGTGGCTCAGCTCCAATCTATGTGAAAAACATTCTCCCCCGGGGGGCGGCCATTCAGGATGG
CCGACTTAAGGCAGGAGACAGACTTATAGAGGTAAATGGAGTAGATTTAGTGGGCAAATCCCAAGAGGAAGTTGTTTCGCTGTTGAGAAG
CACCAAGATGGAAGGAACTGTGAGCCTTCTGGTCTTTCGCCAGGAAGACGCCTTCCACCCAAGGGAACTGAAAGCAGAAGATGAGGATAT
TGTTCTTACACCTGATGGCACCAGGGAATTTCTGACATTTGAAGTCCCACTTAATGATTCAGGATCTGCAGGCCTTGGTGTCAGTGTCAA
AGGTAACCGGTCAAAAGAGAACCACGCAGATTTGGGAATCTTTGTCAAGTCCATTATTAATGGAGGAGCAGCATCTAAAGATGGAAGGCT
TCGGGTGAATGATCAACTGATAGCAGTAAATGGAGAATCCCTGTTGGGCAAGACAAACCAAGATGCCATGGAAACCCTAAGAAGGTCTAT
GTCTACTGAAGGCAATAAACGAGGAATGATCCAGCTTATTGTTGCAAGGAGAATAAGCAAGTGCAATGAGCTGAAGTCACCTGGGAGCCC
CCCTGGACCTGAGCTGCCCATTGAAACAGCGTTGGATGATAGAGAACGAAGAATTTCCCATTCCCTCTACAGTGGGATTGAGGGGCTTGA
TGAATCGCCCAGCAGAAATGCTGCCCTCAGTAGGATAATGGGTAAATACCAGCTGTCCCCTACAGTGAATATGCCCCAAGATGACACTGT
CATTATAGAAGATGACAGGTTGCCAGTGCTTCCTCCACATCTCTCTGACCAGTCCTCTTCCAGCTCCCATGATGATGTGGGGTTTGTGAC
GGCAGATGCTGGTACTTGGGCCAAGGCTGCAATCAGTGATTCAGCCGACTGCTCTTTGAGTCCAGATGTTGATCCAGTTCTTGCTTTTCA
ACGAGAAGGATTTGGACGTCAGATAGCTGACGAGACTAAACTCAATACAGTGGATGACCAGAAAGCAGGTTCTCCCAGCAGAGATGTGGG
TCCTTCCCTGGGTCTGAAGAAGTCAAGCTCGTTGGAGAGTCTGCAGACCGCAGTTGCCGAGGTGACTTTGAATGGGGATATTCCTTTCCA
TCGTCCACGGCCGCGGATAATCAGAGGCAGGGGATGCAATGAGAGCTTCAGAGCTGCCATCGACAAATCTTATGATAAACCCGCGGTAGA
TGATGATGATGAAGGCATGGAGACCTTGGAAGAAGACACAGAAGAAAGTTCAAGATCAGGGAGAGAGTCTGTATCCACAGCCAGTGATCA
GCCTTCCCACTCTCTGGAGAGACAAATGAATGGAAACCAAGAGAAAGGTGATAAGACTGATAGAAAAAAGGATAAAACTGGAAAAGAAAA
GAAGAAAGATAGAGATAAGGAGAAGGATAAAATGAAAGCCAAGAAGGGAATGCTGAAGGGCTTGGGAGACATGTTCAGGTTTGGCAAACA
TCGAAAAGATGACAAGATTGAGAAAACGGGTAAAATAAAAATACAGGAATCCTTTACATCAGAAGAGGAGAGGATACGAATGAAGCAGGA
GCAGGAGAGGATTCAAGCCAAAACTCGAGAATTTAGGGAACGACAAGCTCGAGAGCGTGACTATGCTGAAATTCAAGATTTTCATCGGAC
ATTTGGCTGTGATGATGAGTTAATGTATGGGGGAGTTTCTTCTTATGAAGGTTCCATGGCTCTCAACGCTAGACCTCAGAGCCCACGAGA
AGGGCATATGATGGATGCTTTGTATGCCCAAGTCAAGAAGCCGCGGAATTCCAAACCCTCACCTGTAGACAGTAACAGATCAACTCCTAG
CAATCATGATCGGATACAGCGTCTGAGGCAAGAATTTCAGCAAGCAAAGCAAGATGAAGATGTAGAAGATCGTCGGCGGACCTATAGTTT
TGAGCAACCCTGGCCGAACGCACGGCCGGCGACGCAGAGCGGGCGACACTCGGTGTCCGTGGAGGTGCAGATGCAGCGGCAGCGGCAGGA
GGAGCGCGAGAGCTCCCAGCAGGCCCAGCGCCAGTACAGCTCTCTGCCTCGGCAAAGCAGGAAAAATGCCAGCTCGGTCTCCCAGGACTC
TTGGGAGCAGAACTACTCCCCTGGGGAAGGCTTCCAGAGTGCCAAAGAGAACCCCAGGTACTCCAGCTACCAAGGCTCCAGGAACGGCTA
CCTGGGAGGACATGGCTTCAACGCCAGGGTCATGCTGGAAACTCAGGAGCTCCTTCGCCAGGAACAGAGGCGGAAGGAGCAGCAGATGAA
GAAGCAGCCTCCTTCCGAGGGGCCCAGCAACTATGACTCGTATAAGAAAGTCCAGGACCCCAGTTACGCCCCTCCCAAGGGGCCCTTCCG
GCAAGATGTGCCCCCCTCCCCTTCTCAGGTTGCGAGGCTGAACAGACTTCAGACTCCTGAGAAAGGGAGGCCCTTCTATTCCTGAGCACG
CAAATAACGGATGCTTCATGTCGCGCAATAAAAGACATTTTCCTATGAAGACTTGTATTTTGGGAGTTTTTTTAAAACCTCGATGGTACT
ATGGAGTATTTCTGTTGTTGGTATCAGTGCCTTTAAGCGGTGTAGGCAAAGAAATGGAAGGCCTTAATGTCTTTGCCACTATGTCTCAAG
TGTCTGTTTCATGGAAGGATTTCCCACCCTGTGACAATCATCTGTTTGAGGTGTTCATATGCTCTGCGCCTCTCCACAGTACCAGGAATC
TCGGCCCTACTCATGAGTTGTCCGCGGCTTGGTTGTAACATCCCTGCACCACTTGCAGTGACAAATTCACCTGAAGTGGAGGATGACGTG
CGGCCCTGTTTCTCCCTCTAAGTTCTCTTAGCTATGGGATGACATCTTAGTCTCTGGTGGAGGAAAAGTGGGCGACATACACCAAAAATT
GGGGCTTTCTGGTACTTCACAGCACAGCCATTTGTCGTACTTTGTCATCACTGTGGTTTTCTCTTTCCTTTCTCAGCTCTTTGTGACGGG
AGAGTCGGTCATCCTATTACAGAAGCTAAGCCATAGTCCAACATTGTTTGGTCACCATGGGGGTCCTTTTGTAACTGCCTTATGACTCAA
CATTACCAATAAAGTGATGATCCTGGTCTGCGTTTATACATACGCTTGTTCGGTCCTGTTCCTGACACGTGGGTTGAGTCACCACAGCTC
TGTGTGGGGAACGTGGGAGACAGGAGTGGCTCCTGCCGGGGGAAGCTGGGCCTGCCATTGGCCCTGTGTCTATCATGAGGGGAGAGCTAA
GAAAGAAATTCTCCTAGGAAGAGCTCATGGCCCAGTACATCCTAGTAATTATTTTAATTAGTTTTTGTTCTGACAGCTTGTCAGGAAGGG
CACAGAATGGGACAGAGATAAACCAGACAGTCATTTTGATCTGCTCTCTACGGTTTTTCAAGTCAGAGGCAATTGATGCTTGTCTAATGC
ATCCACACACTGCATGTCTGACTGGCGATGCCGCGCTCCTAAGTAGTTCTGCCATGAAACATAAAAGACAAAGGAAAAGCCGTTACACAT
CACACAGAGAACATTTTCGGGTCCCACAGCGGTGGTGGCAGGAAGCTCACTCTCGCGTCAGTATTAGAGTGTGTGTGTGGGTCTCGGGGA
TCTCGGTGGCTCCCATCTTCCTTCATTGTTCTGAACATCCTGTATTGTAAACCATGGCTGGGGTGCTAAAGTGCCTGTGAATCCCGATGT
GGAAAAAGCTGGAGGTGAAAGCTCAGCATACCATGTATTTACTTTAAAAACAGAAAAAAAGACATGTATGGATATGTCTATTTTTTTTTT
ATTGGCACATTGTATTTTTGTGTTGACTTGTTTTTAGAAATGATGTGTCCACACACGTACCCGTGTCTCTTCTGCATTTCTGTGTCATGG
TTCTGTTTCTTAATCACGTGCGGCGGTGTCTAAGTGGTGTTACCAGTGTACGCGCAGTGACCTTGGATGACAGTGGCTCTTTCTCACAGC

>20659_20659_7_CUL2-PARD3_CUL2_chr10_35333494_ENST00000374746_PARD3_chr10_34806087_ENST00000545260_length(amino acids)=1430AA_BP=0
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVRHLHKRVLESEEQVLVMYHRY
WEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQAILIRMLLREIKNDRGGEDPNQKV
IHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYMEKLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGS
ELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKDE
DGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDG
DLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSR
LPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDR
LIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKEN
HADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPI
ETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWA
KAAISDSADCSLSPDVDPVLAFQREGFGRQIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRII
RGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKE
KDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDEL
MYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRRTYSFEQPWPNA
RPATQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSPGEGFQSAKENPRYSSYQGSRNGYLGGHGFN

--------------------------------------------------------------
>20659_20659_8_CUL2-PARD3_CUL2_chr10_35333494_ENST00000374746_PARD3_chr10_34806087_ENST00000545693_length(transcript)=6146nt_BP=736nt
ATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACAATAAAAGC
CGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCTGAACCCCT
TGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAAGAACAAGT
ACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACCCAGTTTAT
TAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGAGAGCTAGC
ATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGATCGTGGTGG
AGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTAAAGTTTTA
TCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCAAACTGCTC
ACAGTATATGGAAAAGCTGGTAGCAGTGTTTGATGAGCAGGATCCACATCACGGAGGTGATGGCACCAGTGCCAGTTCCACGGGTACCCA
GAGCCCAGAGATATTTGGTAGTGAGCTTGGCACCAACAATGTCTCAGCCTTTCAGCCTTACCAAGCAACAAGTGAAATTGAGGTCACACC
TTCAGTCCTTCGAGCAAATATGCCTCTTCATGTTCGACGCAGTAGTGACCCAGCTCTAATTGGCCTCTCCACTTCTGTCAGTGATAGTAA
TTTTTCCTCTGAAGAGCCTTCAAGGAAAAATCCCACACGCTGGTCAACAACAGCTGGCTTCCTCAAGCAGAACACTGCTGGGAGTCCTAA
AACCTGCGACAGGAAGAAAGATGAAAACTACAGAAGCCTCCCGCGGGATACTAGTAACTGGTCTAACCAATTTCAGAGAGACAATGCTCG
CTCGTCTCTGAGTGCCAGTCACCCAATGGTGGGCAAGTGGCTGGAGAAACAAGAACAGGATGAGGATGGGACAGAAGAGGATAACAGTCG
TGTTGAACCTGTTGGACATGCTGACACGGGTTTGGAGCATATACCCAACTTTTCTCTGGATGATATGGTAAAGCTCGTAGAAGTCCCCAA
CGATGGAGGGCCTCTGGGAATCCACGTAGTGCCTTTCAGTGCTCGAGGCGGCAGAACCCTGGGGTTATTAGTAAAACGATTGGAGAAAGG
TGGTAAAGCTGAACATGAAAATCTTTTTCGTGAGAATGATTGCATTGTCAGGATTAATGATGGCGACCTTCGAAATAGAAGATTTGAACA
AGCACAACATATGTTTCGCCAAGCCATGCGTACACCCATCATTTGGTTCCATGTGGTTCCTGCAGCAAATAAAGAGCAGTATGAACAACT
ATCCCAAAGTGAGAAGAACAATTACTATTCAAGCCGTTTTAGCCCTGACAGCCAGTATATTGACAACAGGAGTGTGAACAGTGCAGGGCT
TCACACGGTGCAGAGAGCACCCCGACTGAACCACCCGCCTGAGCAGATAGACTCTCACTCAAGACTACCTCATAGCGCACACCCCTCGGG
AAAACCACCATCCGCTCCAGCCTCGGCACCTCAGAATGTATTTAGTACGACTGTAAGCAGTGGTTATAACACCAAAAAAATAGGCAAGAG
GCTTAATATCCAGCTTAAGAAAGGTACAGAAGGTTTGGGATTCAGCATCACTTCCAGAGATGTAACAATAGGTGGCTCAGCTCCAATCTA
TGTGAAAAACATTCTCCCCCGGGGGGCGGCCATTCAGGATGGCCGACTTAAGGCAGGAGACAGACTTATAGAGGTAAATGGAGTAGATTT
AGTGGGCAAATCCCAAGAGGAAGTTGTTTCGCTGTTGAGAAGCACCAAGATGGAAGGAACTGTGAGCCTTCTGGTCTTTCGCCAGGAAGA
CGCCTTCCACCCAAGGGAACTGAAAGCAGAAGATGAGGATATTGTTCTTACACCTGATGGCACCAGGGAATTTCTGACATTTGAAGTCCC
ACTTAATGATTCAGGATCTGCAGGCCTTGGTGTCAGTGTCAAAGGTAACCGGTCAAAAGAGAACCACGCAGATTTGGGAATCTTTGTCAA
GTCCATTATTAATGGAGGAGCAGCATCTAAAGATGGAAGGCTTCGGGTGAATGATCAACTGATAGCAGTAAATGGAGAATCCCTGTTGGG
CAAGACAAACCAAGATGCCATGGAAACCCTAAGAAGGTCTATGTCTACTGAAGGCAATAAACGAGGAATGATCCAGCTTATTGTTGCAAG
GAGAATAAGCAAGTGCAATGAGCTGAAGTCACCTGGGAGCCCCCCTGGACCTGAGCTGCCCATTGAAACAGCGTTGGATGATAGAGAACG
AAGAATTTCCCATTCCCTCTACAGTGGGATTGAGGGGCTTGATGAATCGCCCAGCAGAAATGCTGCCCTCAGTAGGATAATGGGTAAATA
CCAGCTGTCCCCTACAGTGAATATGCCCCAAGATGACACTGTCATTATAGAAGATGACAGGTTGCCAGTGCTTCCTCCACATCTCTCTGA
CCAGTCCTCTTCCAGCTCCCATGATGATGTGGGGTTTGTGACGGCAGATGCTGGTACTTGGGCCAAGGCTGCAATCAGTGATTCAGCCGA
CTGCTCTTTGAGTCCAGATGTTGATCCAGTTCTTGCTTTTCAACGAGAAGGATTTGGACGTCAGAGTATGTCAGAAAAACGCACAAAGCA
ATTTTCAGATGCCAGTCAATTGGATTTCGTTAAAACACGAAAATCAAAAAGCATGGATTTAGGTATAGCTGACGAGACTAAACTCAATAC
AGTGGATGACCAGAAAGCAGGTTCTCCCAGCAGAGATGTGGGTCCTTCCCTGGGTCTGAAGAAGTCAAGCTCGTTGGAGAGTCTGCAGAC
CGCAGTTGCCGAGGTGACTTTGAATGGGGATATTCCTTTCCATCGTCCACGGCCGCGGATAATCAGAGGCAGGGGATGCAATGAGAGCTT
CAGAGCTGCCATCGACAAATCTTATGATAAACCCGCGGTAGATGATGATGATGAAGGCATGGAGACCTTGGAAGAAGACACAGAAGAAAG
TTCAAGATCAGGGAGAGAGTCTGTATCCACAGCCAGTGATCAGCCTTCCCACTCTCTGGAGAGACAAATGAATGGAAACCAAGAGAAAGG
TGATAAGACTGATAGAAAAAAGGATAAAACTGGAAAAGAAAAGAAGAAAGATAGAGATAAGGAGAAGGATAAAATGAAAGCCAAGAAGGG
AATGCTGAAGGGCTTGGGAGACATGTTCAGGTTTGGCAAACATCGAAAAGATGACAAGATTGAGAAAACGGGTAAAATAAAAATACAGGA
ATCCTTTACATCAGAAGAGGAGAGGATACGAATGAAGCAGGAGCAGGAGAGGATTCAAGCCAAAACTCGAGAATTTAGGGAACGACAAGC
TCGAGAGCGTGACTATGCTGAAATTCAAGATTTTCATCGGACATTTGGCTGTGATGATGAGTTAATGTATGGGGGAGTTTCTTCTTATGA
AGGTTCCATGGCTCTCAACGCTAGACCTCAGAGCCCACGAGAAGGGCATATGATGGATGCTTTGTATGCCCAAGTCAAGAAGCCGCGGAA
TTCCAAACCCTCACCTGTAGACAGTAACAGATCAACTCCTAGCAATCATGATCGGATACAGCGTCTGAGGCAAGAATTTCAGCAAGCAAA
GCAAGATGAAGATGTAGAAGATCGTCGGCGGACCTATAGTTTTGAGCAACCCTGGCCGAACGCACGGCCGGCGACGCAGAGCGGGCGACA
CTCGGTGTCCGTGGAGGTGCAGATGCAGCGGCAGCGGCAGGAGGAGCGCGAGAGCTCCCAGCAGGCCCAGCGCCAGTACAGCTCTCTGCC
TCGGCAAAGCAGGAAAAATGCCAGCTCGGTCTCCCAGGACTCTTGGGAGCAGAACTACTCCCCTGGGGAAGGCTTCCAGAGTGCCAAAGA
GAACCCCAGGTACTCCAGCTACCAAGGCTCCAGGAACGGCTACCTGGGAGGACATGGCTTCAACGCCAGGGTCATGCTGGAAACTCAGGA
GCTCCTTCGCCAGGAACAGAGGCGGAAGGAGCAGCAGATGAAGAAGCAGCCTCCTTCCGAGGGGCCCAGCAACTATGACTCGTATAAGAA
AGTCCAGGACCCCAGTTACGCCCCTCCCAAGGGGCCCTTCCGGCAAGATGTGCCCCCCTCCCCTTCTCAGGTTGCGAGGCTGAACAGACT
TCAGACTCCTGAGAAAGGGAGGCCCTTCTATTCCTGAGCACGCAAATAACGGATGCTTCATGTCGCGCAATAAAAGACATTTTCCTATGA
AGACTTGTATTTTGGGAGTTTTTTTAAAACCTCGATGGTACTATGGAGTATTTCTGTTGTTGGTATCAGTGCCTTTAAGCGGTGTAGGCA
AAGAAATGGAAGGCCTTAATGTCTTTGCCACTATGTCTCAAGTGTCTGTTTCATGGAAGGATTTCCCACCCTGTGACAATCATCTGTTTG
AGGTGTTCATATGCTCTGCGCCTCTCCACAGTACCAGGAATCTCGGCCCTACTCATGAGTTGTCCGCGGCTTGGTTGTAACATCCCTGCA
CCACTTGCAGTGACAAATTCACCTGAAGTGGAGGATGACGTGCGGCCCTGTTTCTCCCTCTAAGTTCTCTTAGCTATGGGATGACATCTT
AGTCTCTGGTGGAGGAAAAGTGGGCGACATACACCAAAAATTGGGGCTTTCTGGTACTTCACAGCACAGCCATTTGTCGTACTTTGTCAT
CACTGTGGTTTTCTCTTTCCTTTCTCAGCTCTTTGTGACGGGAGAGTCGGTCATCCTATTACAGAAGCTAAGCCATAGTCCAACATTGTT
TGGTCACCATGGGGGTCCTTTTGTAACTGCCTTATGACTCAACATTACCAATAAAGTGATGATCCTGGTCTGCGTTTATACATACGCTTG
TTCGGTCCTGTTCCTGACACGTGGGTTGAGTCACCACAGCTCTGTGTGGGGAACGTGGGAGACAGGAGTGGCTCCTGCCGGGGGAAGCTG
GGCCTGCCATTGGCCCTGTGTCTATCATGAGGGGAGAGCTAAGAAAGAAATTCTCCTAGGAAGAGCTCATGGCCCAGTACATCCTAGTAA
TTATTTTAATTAGTTTTTGTTCTGACAGCTTGTCAGGAAGGGCACAGAATGGGACAGAGATAAACCAGACAGTCATTTTGATCTGCTCTC
TACGGTTTTTCAAGTCAGAGGCAATTGATGCTTGTCTAATGCATCCACACACTGCATGTCTGACTGGCGATGCCGCGCTCCTAAGTAGTT
CTGCCATGAAACATAAAAGACAAAGGAAAAGCCGTTACACATCACACAGAGAACATTTTCGGGTCCCACAGCGGTGGTGGCAGGAAGCTC
ACTCTCGCGTCAGTATTAGAGTGTGTGTGTGGGTCTCGGGGATCTCGGTGGCTCCCATCTTCCTTCATTGTTCTGAACATCCTGTATTGT
AAACCATGGCTGGGGTGCTAAAGTGCCTGTGAATCCCGATGTGGAAAAAGCTGGAGGTGAAAGCTCAGCATACCATGTATTTACTTTAAA
AACAGAAAAAAAGACATGTATGGATATGTCTATTTTTTTTTTATTGGCACATTGTATTTTTGTGTTGACTTGTTTTTAGAAATGATGTGT
CCACACACGTACCCGTGTCTCTTCTGCATTTCTGTGTCATGGTTCTGTTTCTTAATCACGTGCGGCGGTGTCTAAGTGGTGTTACCAGTG
TACGCGCAGTGACCTTGGATGACAGTGGCTCTTTCTCACAGCCTCCCCTGAGCTGTGAGAAACAGCTTTCTCTGTACATATGCAACTCCT

>20659_20659_8_CUL2-PARD3_CUL2_chr10_35333494_ENST00000374746_PARD3_chr10_34806087_ENST00000545693_length(amino acids)=1504AA_BP=0
MSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERLYTETKIFLENHVRHLHKRVLESEEQVLVMYHRY
WEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMWRKLMVEPLQAILIRMLLREIKNDRGGEDPNQKV
IHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYMEKLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGS
ELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKD
ENYRSLPRDTSNWSNQFQRDNARSSLSASHPMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGI
HVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNN
YYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKK
GTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPREL
KAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAM
ETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGKYQLSPTVN
MPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQL
DFVKTRKSKSMDLGIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKS
YDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGD
MFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNA
RPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRRTYSFEQPWPNARPATQSGRHSVSVEVQ
MQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSPGEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVMLETQELLRQEQR

--------------------------------------------------------------
>20659_20659_9_CUL2-PARD3_CUL2_chr10_35333494_ENST00000537177_PARD3_chr10_34806087_ENST00000346874_length(transcript)=6179nt_BP=833nt
ATGTTGCAGTTGAGCCCAAACTGAATGCTGTCTGTAGAAGGAAACAACAAACTTTGTACTTTATGTACAGAGTAACATGGTCAACTTTTT
GGCTTAGATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACAA
TAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCTG
AACCCCTTGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAAG
AACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACCC
AGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGAG
AGCTAGCATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGATC
GTGGTGGAGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTAA
AGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCAA
ACTGCTCACAGTATATGGAAAAGCTGGTAGCAGTGTTTGATGAGCAGGATCCACATCACGGAGGTGATGGCACCAGTGCCAGTTCCACGG
GTACCCAGAGCCCAGAGATATTTGGTAGTGAGCTTGGCACCAACAATGTCTCAGCCTTTCAGCCTTACCAAGCAACAAGTGAAATTGAGG
TCACACCTTCAGTCCTTCGAGCAAATATGCCTCTTCATGTTCGACGCAGTAGTGACCCAGCTCTAATTGGCCTCTCCACTTCTGTCAGTG
ATAGTAATTTTTCCTCTGAAGAGCCTTCAAGGAAAAATCCCACACGCTGGTCAACAACAGCTGGCTTCCTCAAGCAGAACACTGCTGGGA
GTCCTAAAACCTGCGACAGGAAGAAAGATGAAAACTACAGAAGCCTCCCGCGGGATACTAGTAACTGGTCTAACCAATTTCAGAGAGACA
ATGCTCGCTCGTCTCTGAGTGCCAGTCACCCAATGGTGGGCAAGTGGCTGGAGAAACAAGAACAGGATGAGGATGGGACAGAAGAGGATA
ACAGTCGTGTTGAACCTGTTGGACATGCTGACACGGGTTTGGAGCATATACCCAACTTTTCTCTGGATGATATGGTAAAGCTCGTAGAAG
TCCCCAACGATGGAGGGCCTCTGGGAATCCACGTAGTGCCTTTCAGTGCTCGAGGCGGCAGAACCCTGGGGTTATTAGTAAAACGATTGG
AGAAAGGTGGTAAAGCTGAACATGAAAATCTTTTTCGTGAGAATGATTGCATTGTCAGGATTAATGATGGCGACCTTCGAAATAGAAGAT
TTGAACAAGCACAACATATGTTTCGCCAAGCCATGCGTACACCCATCATTTGGTTCCATGTGGTTCCTGCAGCAAATAAAGAGCAGTATG
AACAACTATCCCAAAGTGAGAAGAACAATTACTATTCAAGCCGTTTTAGCCCTGACAGCCAGTATATTGACAACAGGAGTGTGAACAGTG
CAGGGCTTCACACGGTGCAGAGAGCACCCCGACTGAACCACCCGCCTGAGCAGATAGACTCTCACTCAAGACTACCTCATAGCGCACACC
CCTCGGGAAAACCACCATCCGCTCCAGCCTCGGCACCTCAGAATGTATTTAGTACGACTGTAAGCAGTGGTTATAACACCAAAAAAATAG
GCAAGAGGCTTAATATCCAGCTTAAGAAAGGTACAGAAGGTTTGGGATTCAGCATCACTTCCAGAGATGTAACAATAGGTGGCTCAGCTC
CAATCTATGTGAAAAACATTCTCCCCCGGGGGGCGGCCATTCAGGATGGCCGACTTAAGGCAGGAGACAGACTTATAGAGGTAAATGGAG
TAGATTTAGTGGGCAAATCCCAAGAGGAAGTTGTTTCGCTGTTGAGAAGCACCAAGATGGAAGGAACTGTGAGCCTTCTGGTCTTTCGCC
AGGAAGACGCCTTCCACCCAAGGGAACTGAATGCAGAGCCAAGCCAGATGCAGATTCCAAAAGAAACGAAAGCAGAAGATGAGGATATTG
TTCTTACACCTGATGGCACCAGGGAATTTCTGACATTTGAAGTCCCACTTAATGATTCAGGATCTGCAGGCCTTGGTGTCAGTGTCAAAG
GTAACCGGTCAAAAGAGAACCACGCAGATTTGGGAATCTTTGTCAAGTCCATTATTAATGGAGGAGCAGCATCTAAAGATGGAAGGCTTC
GGGTGAATGATCAACTGATAGCAGTAAATGGAGAATCCCTGTTGGGCAAGACAAACCAAGATGCCATGGAAACCCTAAGAAGGTCTATGT
CTACTGAAGGCAATAAACGAGGAATGATCCAGCTTATTGTTGCAAGGAGAATAAGCAAGTGCAATGAGCTGAAGTCACCTGGGAGCCCCC
CTGGACCTGAGCTGCCCATTGAAACAGCGTTGGATGATAGAGAACGAAGAATTTCCCATTCCCTCTACAGTGGGATTGAGGGGCTTGATG
AATCGCCCAGCAGAAATGCTGCCCTCAGTAGGATAATGGGTGAGTCAGGTAAATACCAGCTGTCCCCTACAGTGAATATGCCCCAAGATG
ACACTGTCATTATAGAAGATGACAGGTTGCCAGTGCTTCCTCCACATCTCTCTGACCAGTCCTCTTCCAGCTCCCATGATGATGTGGGGT
TTGTGACGGCAGATGCTGGTACTTGGGCCAAGGCTGCAATCAGTGATTCAGCCGACTGCTCTTTGAGTCCAGATGTTGATCCAGTTCTTG
CTTTTCAACGAGAAGGATTTGGACGTCAGAGTATGTCAGAAAAACGCACAAAGCAATTTTCAGATGCCAGTCAATTGGATTTCGTTAAAA
CACGAAAATCAAAAAGCATGGATTTAGGTATAGCTGACGAGACTAAACTCAATACAGTGGATGACCAGAAAGCAGGTTCTCCCAGCAGAG
ATGTGGGTCCTTCCCTGGGTCTGAAGAAGTCAAGCTCGTTGGAGAGTCTGCAGACCGCAGTTGCCGAGGTGACTTTGAATGGGGATATTC
CTTTCCATCGTCCACGGCCGCGGATAATCAGAGGCAGGGGATGCAATGAGAGCTTCAGAGCTGCCATCGACAAATCTTATGATAAACCCG
CGGTAGATGATGATGATGAAGGCATGGAGACCTTGGAAGAAGACACAGAAGAAAGTTCAAGATCAGGGAGAGAGTCTGTATCCACAGCCA
GTGATCAGCCTTCCCACTCTCTGGAGAGACAAATGAATGGAAACCAAGAGAAAGGTGATAAGACTGATAGAAAAAAGGATAAAACTGGAA
AAGAAAAGAAGAAAGATAGAGATAAGGAGAAGGATAAAATGAAAGCCAAGAAGGGAATGCTGAAGGGCTTGGGAGACATGTTCAGGATTC
AAGCCAAAACTCGAGAATTTAGGGAACGACAAGCTCGAGAGCGTGACTATGCTGAAATTCAAGATTTTCATCGGACATTTGGCTGTGATG
ATGAGTTAATGTATGGGGGAGTTTCTTCTTATGAAGGTTCCATGGCTCTCAACGCTAGACCTCAGAGCCCACGAGAAGGGCATATGATGG
ATGCTTTGTATGCCCAAGTCAAGAAGCCGCGGAATTCCAAACCCTCACCTGTAGACAGTAACAGATCAACTCCTAGCAATCATGATCGGA
TACAGCGTCTGAGGCAAGAATTTCAGCAAGCAAAGCAAGATGAAGATGTAGAAGATCGTCGGCGGACCTATAGTTTTGAGCAACCCTGGC
CGAACGCACGGCCGGCGACGCAGAGCGGGCGACACTCGGTGTCCGTGGAGGTGCAGATGCAGCGGCAGCGGCAGGAGGAGCGCGAGAGCT
CCCAGCAGGCCCAGCGCCAGTACAGCTCTCTGCCTCGGCAAAGCAGGAAAAATGCCAGCTCGGTCTCCCAGGACTCTTGGGAGCAGAACT
ACTCCCCTGGGGAAGGCTTCCAGAGTGCCAAAGAGAACCCCAGGTACTCCAGCTACCAAGGCTCCAGGAACGGCTACCTGGGAGGACATG
GCTTCAACGCCAGGGTCATGCTGGAAACTCAGGAGCTCCTTCGCCAGGAACAGAGGCGGAAGGAGCAGCAGATGAAGAAGCAGCCTCCTT
CCGAGGGGCCCAGCAACTATGACTCGTATAAGAAAGTCCAGGACCCCAGTTACGCCCCTCCCAAGGGGCCCTTCCGGCAAGATGTGCCCC
CCTCCCCTTCTCAGGTTGCGAGGCTGAACAGACTTCAGACTCCTGAGAAAGGGAGGCCCTTCTATTCCTGAGCACGCAAATAACGGATGC
TTCATGTCGCGCAATAAAAGACATTTTCCTATGAAGACTTGTATTTTGGGAGTTTTTTTAAAACCTCGATGGTACTATGGAGTATTTCTG
TTGTTGGTATCAGTGCCTTTAAGCGGTGTAGGCAAAGAAATGGAAGGCCTTAATGTCTTTGCCACTATGTCTCAAGTGTCTGTTTCATGG
AAGGATTTCCCACCCTGTGACAATCATCTGTTTGAGGTGTTCATATGCTCTGCGCCTCTCCACAGTACCAGGAATCTCGGCCCTACTCAT
GAGTTGTCCGCGGCTTGGTTGTAACATCCCTGCACCACTTGCAGTGACAAATTCACCTGAAGTGGAGGATGACGTGCGGCCCTGTTTCTC
CCTCTAAGTTCTCTTAGCTATGGGATGACATCTTAGTCTCTGGTGGAGGAAAAGTGGGCGACATACACCAAAAATTGGGGCTTTCTGGTA
CTTCACAGCACAGCCATTTGTCGTACTTTGTCATCACTGTGGTTTTCTCTTTCCTTTCTCAGCTCTTTGTGACGGGAGAGTCGGTCATCC
TATTACAGAAGCTAAGCCATAGTCCAACATTGTTTGGTCACCATGGGGGTCCTTTTGTAACTGCCTTATGACTCAACATTACCAATAAAG
TGATGATCCTGGTCTGCGTTTATACATACGCTTGTTCGGTCCTGTTCCTGACACGTGGGTTGAGTCACCACAGCTCTGTGTGGGGAACGT
GGGAGACAGGAGTGGCTCCTGCCGGGGGAAGCTGGGCCTGCCATTGGCCCTGTGTCTATCATGAGGGGAGAGCTAAGAAAGAAATTCTCC
TAGGAAGAGCTCATGGCCCAGTACATCCTAGTAATTATTTTAATTAGTTTTTGTTCTGACAGCTTGTCAGGAAGGGCACAGAATGGGACA
GAGATAAACCAGACAGTCATTTTGATCTGCTCTCTACGGTTTTTCAAGTCAGAGGCAATTGATGCTTGTCTAATGCATCCACACACTGCA
TGTCTGACTGGCGATGCCGCGCTCCTAAGTAGTTCTGCCATGAAACATAAAAGACAAAGGAAAAGCCGTTACACATCACACAGAGAACAT
TTTCGGGTCCCACAGCGGTGGTGGCAGGAAGCTCACTCTCGCGTCAGTATTAGAGTGTGTGTGTGGGTCTCGGGGATCTCGGTGGCTCCC
ATCTTCCTTCATTGTTCTGAACATCCTGTATTGTAAACCATGGCTGGGGTGCTAAAGTGCCTGTGAATCCCGATGTGGAAAAAGCTGGAG
GTGAAAGCTCAGCATACCATGTATTTACTTTAAAAACAGAAAAAAAGACATGTATGGATATGTCTATTTTTTTTTTATTGGCACATTGTA
TTTTTGTGTTGACTTGTTTTTAGAAATGATGTGTCCACACACGTACCCGTGTCTCTTCTGCATTTCTGTGTCATGGTTCTGTTTCTTAAT
CACGTGCGGCGGTGTCTAAGTGGTGTTACCAGTGTACGCGCAGTGACCTTGGATGACAGTGGCTCTTTCTCACAGCCTCCCCTGAGCTGT

>20659_20659_9_CUL2-PARD3_CUL2_chr10_35333494_ENST00000537177_PARD3_chr10_34806087_ENST00000346874_length(amino acids)=1516AA_BP=1
MNAVCRRKQQTLYFMYRVTWSTFWLRFQHYTCTMSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERL
YTETKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMW
RKLMVEPLQAILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYME
KLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSE
EPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASHPMVGKWLEKQEQDEDGTEEDNSRVEPV
GHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHM
FRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPS
APASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKS
QEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELNAEPSQMQIPKETKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKEN
HADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPI
ETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGESGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAG
TWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLGIADETKLNTVDDQKAGSPSRDVGPSLG
LKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHS
LERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGG
VSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRRTYSFEQPWPNARPAT
QSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSPGEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVM

--------------------------------------------------------------
>20659_20659_10_CUL2-PARD3_CUL2_chr10_35333494_ENST00000537177_PARD3_chr10_34806087_ENST00000350537_length(transcript)=6152nt_BP=833nt
ATGTTGCAGTTGAGCCCAAACTGAATGCTGTCTGTAGAAGGAAACAACAAACTTTGTACTTTATGTACAGAGTAACATGGTCAACTTTTT
GGCTTAGATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACAA
TAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCTG
AACCCCTTGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAAG
AACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACCC
AGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGAG
AGCTAGCATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGATC
GTGGTGGAGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTAA
AGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCAA
ACTGCTCACAGTATATGGAAAAGCTGGTAGCAGTGTTTGATGAGCAGGATCCACATCACGGAGGTGATGGCACCAGTGCCAGTTCCACGG
GTACCCAGAGCCCAGAGATATTTGGTAGTGAGCTTGGCACCAACAATGTCTCAGCCTTTCAGCCTTACCAAGCAACAAGTGAAATTGAGG
TCACACCTTCAGTCCTTCGAGCAAATATGCCTCTTCATGTTCGACGCAGTAGTGACCCAGCTCTAATTGGCCTCTCCACTTCTGTCAGTG
ATAGTAATTTTTCCTCTGAAGAGCCTTCAAGGAAAAATCCCACACGCTGGTCAACAACAGCTGGCTTCCTCAAGCAGAACACTGCTGGGA
GTCCTAAAACCTGCGACAGGAAGAAAGATGAAAACTACAGAAGCCTCCCGCGGGATACTAGTAACTGGTCTAACCAATTTCAGAGAGACA
ATGCTCGCTCGTCTCTGAGTGCCAGTCACCCAATGGTGGGCAAGTGGCTGGAGAAACAAGAACAGGATGAGGATGGGACAGAAGAGGATA
ACAGTCGTGTTGAACCTGTTGGACATGCTGACACGGGTTTGGAGCATATACCCAACTTTTCTCTGGATGATATGGTAAAGCTCGTAGAAG
TCCCCAACGATGGAGGGCCTCTGGGAATCCACGTAGTGCCTTTCAGTGCTCGAGGCGGCAGAACCCTGGGGTTATTAGTAAAACGATTGG
AGAAAGGTGGTAAAGCTGAACATGAAAATCTTTTTCGTGAGAATGATTGCATTGTCAGGATTAATGATGGCGACCTTCGAAATAGAAGAT
TTGAACAAGCACAACATATGTTTCGCCAAGCCATGCGTACACCCATCATTTGGTTCCATGTGGTTCCTGCAGCAAATAAAGAGCAGTATG
AACAACTATCCCAAAGTGAGAAGAACAATTACTATTCAAGCCGTTTTAGCCCTGACAGCCAGTATATTGACAACAGGAGTGTGAACAGTG
CAGGGCTTCACACGGTGCAGAGAGCACCCCGACTGAACCACCCGCCTGAGCAGATAGACTCTCACTCAAGACTACCTCATAGCGCACACC
CCTCGGGAAAACCACCATCCGCTCCAGCCTCGGCACCTCAGAATGTATTTAGTACGACTGTAAGCAGTGGTTATAACACCAAAAAAATAG
GCAAGAGGCTTAATATCCAGCTTAAGAAAGGTACAGAAGGTTTGGGATTCAGCATCACTTCCAGAGATGTAACAATAGGTGGCTCAGCTC
CAATCTATGTGAAAAACATTCTCCCCCGGGGGGCGGCCATTCAGGATGGCCGACTTAAGGCAGGAGACAGACTTATAGAGGTAAATGGAG
TAGATTTAGTGGGCAAATCCCAAGAGGAAGTTGTTTCGCTGTTGAGAAGCACCAAGATGGAAGGAACTGTGAGCCTTCTGGTCTTTCGCC
AGGAAGACGCCTTCCACCCAAGGGAACTGAAAGCAGAAGATGAGGATATTGTTCTTACACCTGATGGCACCAGGGAATTTCTGACATTTG
AAGTCCCACTTAATGATTCAGGATCTGCAGGCCTTGGTGTCAGTGTCAAAGGTAACCGGTCAAAAGAGAACCACGCAGATTTGGGAATCT
TTGTCAAGTCCATTATTAATGGAGGAGCAGCATCTAAAGATGGAAGGCTTCGGGTGAATGATCAACTGATAGCAGTAAATGGAGAATCCC
TGTTGGGCAAGACAAACCAAGATGCCATGGAAACCCTAAGAAGGTCTATGTCTACTGAAGGCAATAAACGAGGAATGATCCAGCTTATTG
TTGCAAGGAGAATAAGCAAGTGCAATGAGCTGAAGTCACCTGGGAGCCCCCCTGGACCTGAGCTGCCCATTGAAACAGCGTTGGATGATA
GAGAACGAAGAATTTCCCATTCCCTCTACAGTGGGATTGAGGGGCTTGATGAATCGCCCAGCAGAAATGCTGCCCTCAGTAGGATAATGG
GTAAATACCAGCTGTCCCCTACAGTGAATATGCCCCAAGATGACACTGTCATTATAGAAGATGACAGGTTGCCAGTGCTTCCTCCACATC
TCTCTGACCAGTCCTCTTCCAGCTCCCATGATGATGTGGGGTTTGTGACGGCAGATGCTGGTACTTGGGCCAAGGCTGCAATCAGTGATT
CAGCCGACTGCTCTTTGAGTCCAGATGTTGATCCAGTTCTTGCTTTTCAACGAGAAGGATTTGGACGTCAGATAGCTGACGAGACTAAAC
TCAATACAGTGGATGACCAGAAAGCAGGTTCTCCCAGCAGAGATGTGGGTCCTTCCCTGGGTCTGAAGAAGTCAAGCTCGTTGGAGAGTC
TGCAGACCGCAGTTGCCGAGGTGACTTTGAATGGGGATATTCCTTTCCATCGTCCACGGCCGCGGATAATCAGAGGCAGGGGATGCAATG
AGAGCTTCAGAGCTGCCATCGACAAATCTTATGATAAACCCGCGGTAGATGATGATGATGAAGGCATGGAGACCTTGGAAGAAGACACAG
AAGAAAGTTCAAGATCAGGGAGAGAGTCTGTATCCACAGCCAGTGATCAGCCTTCCCACTCTCTGGAGAGACAAATGAATGGAAACCAAG
AGAAAGGTGATAAGACTGATAGAAAAAAGGATAAAACTGGAAAAGAAAAGAAGAAAGATAGAGATAAGGAGAAGGATAAAATGAAAGCCA
AGAAGGGAATGCTGAAGGGCTTGGGAGACATGTTCAGGTTTGGCAAACATCGAAAAGATGACAAGATTGAGAAAACGGGTAAAATAAAAA
TACAGGAATCCTTTACATCAGAAGAGGAGAGGATACGAATGAAGCAGGAGCAGGAGAGGATTCAAGCCAAAACTCGAGAATTTAGGGAAC
GACAAGCTCGAGAGCGTGACTATGCTGAAATTCAAGATTTTCATCGGACATTTGGCTGTGATGATGAGTTAATGTATGGGGGAGTTTCTT
CTTATGAAGGTTCCATGGCTCTCAACGCTAGACCTCAGAGCCCACGAGAAGGGCATATGATGGATGCTTTGTATGCCCAAGTCAAGAAGC
CGCGGAATTCCAAACCCTCACCTGTAGACAGTAACAGATCAACTCCTAGCAATCATGATCGGATACAGCGTCTGAGGCAAGAATTTCAGC
AAGCAAAGCAAGATGAAGATGTAGAAGATCGTCGGCGGACCTATAGTTTTGAGCAACCCTGGCCGAACGCACGGCCGGCGACGCAGAGCG
GGCGACACTCGGTGTCCGTGGAGGTGCAGATGCAGCGGCAGCGGCAGGAGGAGCGCGAGAGCTCCCAGCAGGCCCAGCGCCAGTACAGCT
CTCTGCCTCGGCAAAGCAGGAAAAATGCCAGCTCGGTCTCCCAGGACTCTTGGGAGCAGAACTACTCCCCTGGGGAAGGCTTCCAGAGTG
CCAAAGAGAACCCCAGGTACTCCAGCTACCAAGGCTCCAGGAACGGCTACCTGGGAGGACATGGCTTCAACGCCAGGGTCATGCTGGAAA
CTCAGGAGCTCCTTCGCCAGGAACAGAGGCGGAAGGAGCAGCAGATGAAGAAGCAGCCTCCTTCCGAGGGGCCCAGCAACTATGACTCGT
ATAAGAAAGTCCAGGACCCCAGTTACGCCCCTCCCAAGGGGCCCTTCCGGCAAGATGTGCCCCCCTCCCCTTCTCAGGTTGCGAGGCTGA
ACAGACTTCAGACTCCTGAGAAAGGGAGGCCCTTCTATTCCTGAGCACGCAAATAACGGATGCTTCATGTCGCGCAATAAAAGACATTTT
CCTATGAAGACTTGTATTTTGGGAGTTTTTTTAAAACCTCGATGGTACTATGGAGTATTTCTGTTGTTGGTATCAGTGCCTTTAAGCGGT
GTAGGCAAAGAAATGGAAGGCCTTAATGTCTTTGCCACTATGTCTCAAGTGTCTGTTTCATGGAAGGATTTCCCACCCTGTGACAATCAT
CTGTTTGAGGTGTTCATATGCTCTGCGCCTCTCCACAGTACCAGGAATCTCGGCCCTACTCATGAGTTGTCCGCGGCTTGGTTGTAACAT
CCCTGCACCACTTGCAGTGACAAATTCACCTGAAGTGGAGGATGACGTGCGGCCCTGTTTCTCCCTCTAAGTTCTCTTAGCTATGGGATG
ACATCTTAGTCTCTGGTGGAGGAAAAGTGGGCGACATACACCAAAAATTGGGGCTTTCTGGTACTTCACAGCACAGCCATTTGTCGTACT
TTGTCATCACTGTGGTTTTCTCTTTCCTTTCTCAGCTCTTTGTGACGGGAGAGTCGGTCATCCTATTACAGAAGCTAAGCCATAGTCCAA
CATTGTTTGGTCACCATGGGGGTCCTTTTGTAACTGCCTTATGACTCAACATTACCAATAAAGTGATGATCCTGGTCTGCGTTTATACAT
ACGCTTGTTCGGTCCTGTTCCTGACACGTGGGTTGAGTCACCACAGCTCTGTGTGGGGAACGTGGGAGACAGGAGTGGCTCCTGCCGGGG
GAAGCTGGGCCTGCCATTGGCCCTGTGTCTATCATGAGGGGAGAGCTAAGAAAGAAATTCTCCTAGGAAGAGCTCATGGCCCAGTACATC
CTAGTAATTATTTTAATTAGTTTTTGTTCTGACAGCTTGTCAGGAAGGGCACAGAATGGGACAGAGATAAACCAGACAGTCATTTTGATC
TGCTCTCTACGGTTTTTCAAGTCAGAGGCAATTGATGCTTGTCTAATGCATCCACACACTGCATGTCTGACTGGCGATGCCGCGCTCCTA
AGTAGTTCTGCCATGAAACATAAAAGACAAAGGAAAAGCCGTTACACATCACACAGAGAACATTTTCGGGTCCCACAGCGGTGGTGGCAG
GAAGCTCACTCTCGCGTCAGTATTAGAGTGTGTGTGTGGGTCTCGGGGATCTCGGTGGCTCCCATCTTCCTTCATTGTTCTGAACATCCT
GTATTGTAAACCATGGCTGGGGTGCTAAAGTGCCTGTGAATCCCGATGTGGAAAAAGCTGGAGGTGAAAGCTCAGCATACCATGTATTTA
CTTTAAAAACAGAAAAAAAGACATGTATGGATATGTCTATTTTTTTTTTATTGGCACATTGTATTTTTGTGTTGACTTGTTTTTAGAAAT
GATGTGTCCACACACGTACCCGTGTCTCTTCTGCATTTCTGTGTCATGGTTCTGTTTCTTAATCACGTGCGGCGGTGTCTAAGTGGTGTT
ACCAGTGTACGCGCAGTGACCTTGGATGACAGTGGCTCTTTCTCACAGCCTCCCCTGAGCTGTGAGAAACAGCTTTCTCTGTACATATGC

>20659_20659_10_CUL2-PARD3_CUL2_chr10_35333494_ENST00000537177_PARD3_chr10_34806087_ENST00000350537_length(amino acids)=1507AA_BP=1
MNAVCRRKQQTLYFMYRVTWSTFWLRFQHYTCTMSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERL
YTETKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMW
RKLMVEPLQAILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYME
KLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSE
EPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASHPMVGKWLEKQEQDEDGTEEDNSRVEPV
GHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHM
FRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPS
APASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKS
QEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIIN
GGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISH
SLYSGIEGLDESPSRNAALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLS
PDVDPVLAFQREGFGRQIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAI
DKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKG
LGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMA
LNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRRTYSFEQPWPNARPATQSGRHSVSV
EVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSPGEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVMLETQELLRQ

--------------------------------------------------------------
>20659_20659_11_CUL2-PARD3_CUL2_chr10_35333494_ENST00000537177_PARD3_chr10_34806087_ENST00000374788_length(transcript)=6281nt_BP=833nt
ATGTTGCAGTTGAGCCCAAACTGAATGCTGTCTGTAGAAGGAAACAACAAACTTTGTACTTTATGTACAGAGTAACATGGTCAACTTTTT
GGCTTAGATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACAA
TAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCTG
AACCCCTTGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAAG
AACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACCC
AGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGAG
AGCTAGCATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGATC
GTGGTGGAGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTAA
AGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCAA
ACTGCTCACAGTATATGGAAAAGCTGGTAGCAGTGTTTGATGAGCAGGATCCACATCACGGAGGTGATGGCACCAGTGCCAGTTCCACGG
GTACCCAGAGCCCAGAGATATTTGGTAGTGAGCTTGGCACCAACAATGTCTCAGCCTTTCAGCCTTACCAAGCAACAAGTGAAATTGAGG
TCACACCTTCAGTCCTTCGAGCAAATATGCCTCTTCATGTTCGACGCAGTAGTGACCCAGCTCTAATTGGCCTCTCCACTTCTGTCAGTG
ATAGTAATTTTTCCTCTGAAGAGCCTTCAAGGAAAAATCCCACACGCTGGTCAACAACAGCTGGCTTCCTCAAGCAGAACACTGCTGGGA
GTCCTAAAACCTGCGACAGGAAGAAAGATGAAAACTACAGAAGCCTCCCGCGGGATACTAGTAACTGGTCTAACCAATTTCAGAGAGACA
ATGCTCGCTCGTCTCTGAGTGCCAGTCACCCAATGGTGGGCAAGTGGCTGGAGAAACAAGAACAGGATGAGGATGGGACAGAAGAGGATA
ACAGTCGTGTTGAACCTGTTGGACATGCTGACACGGGTTTGGAGCATATACCCAACTTTTCTCTGGATGATATGGTAAAGCTCGTAGAAG
TCCCCAACGATGGAGGGCCTCTGGGAATCCACGTAGTGCCTTTCAGTGCTCGAGGCGGCAGAACCCTGGGGTTATTAGTAAAACGATTGG
AGAAAGGTGGTAAAGCTGAACATGAAAATCTTTTTCGTGAGAATGATTGCATTGTCAGGATTAATGATGGCGACCTTCGAAATAGAAGAT
TTGAACAAGCACAACATATGTTTCGCCAAGCCATGCGTACACCCATCATTTGGTTCCATGTGGTTCCTGCAGCAAATAAAGAGCAGTATG
AACAACTATCCCAAAGTGAGAAGAACAATTACTATTCAAGCCGTTTTAGCCCTGACAGCCAGTATATTGACAACAGGAGTGTGAACAGTG
CAGGGCTTCACACGGTGCAGAGAGCACCCCGACTGAACCACCCGCCTGAGCAGATAGACTCTCACTCAAGACTACCTCATAGCGCACACC
CCTCGGGAAAACCACCATCCGCTCCAGCCTCGGCACCTCAGAATGTATTTAGTACGACTGTAAGCAGTGGTTATAACACCAAAAAAATAG
GCAAGAGGCTTAATATCCAGCTTAAGAAAGGTACAGAAGGTTTGGGATTCAGCATCACTTCCAGAGATGTAACAATAGGTGGCTCAGCTC
CAATCTATGTGAAAAACATTCTCCCCCGGGGGGCGGCCATTCAGGATGGCCGACTTAAGGCAGGAGACAGACTTATAGAGGTAAATGGAG
TAGATTTAGTGGGCAAATCCCAAGAGGAAGTTGTTTCGCTGTTGAGAAGCACCAAGATGGAAGGAACTGTGAGCCTTCTGGTCTTTCGCC
AGGAAGACGCCTTCCACCCAAGGGAACTGAATGCAGAGCCAAGCCAGATGCAGATTCCAAAAGAAACGAAAGCAGAAGATGAGGATATTG
TTCTTACACCTGATGGCACCAGGGAATTTCTGACATTTGAAGTCCCACTTAATGATTCAGGATCTGCAGGCCTTGGTGTCAGTGTCAAAG
GTAACCGGTCAAAAGAGAACCACGCAGATTTGGGAATCTTTGTCAAGTCCATTATTAATGGAGGAGCAGCATCTAAAGATGGAAGGCTTC
GGGTGAATGATCAACTGATAGCAGTAAATGGAGAATCCCTGTTGGGCAAGACAAACCAAGATGCCATGGAAACCCTAAGAAGGTCTATGT
CTACTGAAGGCAATAAACGAGGAATGATCCAGCTTATTGTTGCAAGGAGAATAAGCAAGTGCAATGAGCTGAAGTCACCTGGGAGCCCCC
CTGGACCTGAGCTGCCCATTGAAACAGCGTTGGATGATAGAGAACGAAGAATTTCCCATTCCCTCTACAGTGGGATTGAGGGGCTTGATG
AATCGCCCAGCAGAAATGCTGCCCTCAGTAGGATAATGGGTAAATACCAGCTGTCCCCTACAGTGAATATGCCCCAAGATGACACTGTCA
TTATAGAAGATGACAGGTTGCCAGTGCTTCCTCCACATCTCTCTGACCAGTCCTCTTCCAGCTCCCATGATGATGTGGGGTTTGTGACGG
CAGATGCTGGTACTTGGGCCAAGGCTGCAATCAGTGATTCAGCCGACTGCTCTTTGAGTCCAGATGTTGATCCAGTTCTTGCTTTTCAAC
GAGAAGGATTTGGACGTCAGAGTATGTCAGAAAAACGCACAAAGCAATTTTCAGATGCCAGTCAATTGGATTTCGTTAAAACACGAAAAT
CAAAAAGCATGGATTTAGGTATAGCTGACGAGACTAAACTCAATACAGTGGATGACCAGAAAGCAGGTTCTCCCAGCAGAGATGTGGGTC
CTTCCCTGGGTCTGAAGAAGTCAAGCTCGTTGGAGAGTCTGCAGACCGCAGTTGCCGAGGTGACTTTGAATGGGGATATTCCTTTCCATC
GTCCACGGCCGCGGATAATCAGAGGCAGGGGATGCAATGAGAGCTTCAGAGCTGCCATCGACAAATCTTATGATAAACCCGCGGTAGATG
ATGATGATGAAGGCATGGAGACCTTGGAAGAAGACACAGAAGAAAGTTCAAGATCAGGGAGAGAGTCTGTATCCACAGCCAGTGATCAGC
CTTCCCACTCTCTGGAGAGACAAATGAATGGAAACCAAGAGAAAGGTGATAAGACTGATAGAAAAAAGGATAAAACTGGAAAAGAAAAGA
AGAAAGATAGAGATAAGGAGAAGGATAAAATGAAAGCCAAGAAGGGAATGCTGAAGGGCTTGGGAGACATGTTCAGGTTTGGCAAACATC
GAAAAGATGACAAGATTGAGAAAACGGGTAAAATAAAAATACAGGAATCCTTTACATCAGAAGAGGAGAGGATACGAATGAAGCAGGAGC
AGGAGAGGATTCAAGCCAAAACTCGAGAATTTAGGGAACGACAAGCTCGAGAGCGTGACTATGCTGAAATTCAAGATTTTCATCGGACAT
TTGGCTGTGATGATGAGTTAATGTATGGGGGAGTTTCTTCTTATGAAGGTTCCATGGCTCTCAACGCTAGACCTCAGAGCCCACGAGAAG
GGCATATGATGGATGCTTTGTATGCCCAAGTCAAGAAGCCGCGGAATTCCAAACCCTCACCTGTAGACAGTAACAGATCAACTCCTAGCA
ATCATGATCGGATACAGCGTCTGAGGCAAGAATTTCAGCAAGCAAAGCAAGATGAAGATGTAGAAGATCGTCGGCGGACCTATAGTTTTG
AGCAACCCTGGCCGAACGCACGGCCGGCGACGCAGAGCGGGCGACACTCGGTGTCCGTGGAGGTGCAGATGCAGCGGCAGCGGCAGGAGG
AGCGCGAGAGCTCCCAGCAGGCCCAGCGCCAGTACAGCTCTCTGCCTCGGCAAAGCAGGAAAAATGCCAGCTCGGTCTCCCAGGACTCTT
GGGAGCAGAACTACTCCCCTGGGGAAGGCTTCCAGAGTGCCAAAGAGAACCCCAGGTACTCCAGCTACCAAGGCTCCAGGAACGGCTACC
TGGGAGGACATGGCTTCAACGCCAGGGTCATGCTGGAAACTCAGGAGCTCCTTCGCCAGGAACAGAGGCGGAAGGAGCAGCAGATGAAGA
AGCAGCCTCCTTCCGAGGGGCCCAGCAACTATGACTCGTATAAGAAAGTCCAGGACCCCAGTTACGCCCCTCCCAAGGGGCCCTTCCGGC
AAGATGTGCCCCCCTCCCCTTCTCAGGTTGCGAGGCTGAACAGACTTCAGACTCCTGAGAAAGGGAGGCCCTTCTATTCCTGAGCACGCA
AATAACGGATGCTTCATGTCGCGCAATAAAAGACATTTTCCTATGAAGACTTGTATTTTGGGAGTTTTTTTAAAACCTCGATGGTACTAT
GGAGTATTTCTGTTGTTGGTATCAGTGCCTTTAAGCGGTGTAGGCAAAGAAATGGAAGGCCTTAATGTCTTTGCCACTATGTCTCAAGTG
TCTGTTTCATGGAAGGATTTCCCACCCTGTGACAATCATCTGTTTGAGGTGTTCATATGCTCTGCGCCTCTCCACAGTACCAGGAATCTC
GGCCCTACTCATGAGTTGTCCGCGGCTTGGTTGTAACATCCCTGCACCACTTGCAGTGACAAATTCACCTGAAGTGGAGGATGACGTGCG
GCCCTGTTTCTCCCTCTAAGTTCTCTTAGCTATGGGATGACATCTTAGTCTCTGGTGGAGGAAAAGTGGGCGACATACACCAAAAATTGG
GGCTTTCTGGTACTTCACAGCACAGCCATTTGTCGTACTTTGTCATCACTGTGGTTTTCTCTTTCCTTTCTCAGCTCTTTGTGACGGGAG
AGTCGGTCATCCTATTACAGAAGCTAAGCCATAGTCCAACATTGTTTGGTCACCATGGGGGTCCTTTTGTAACTGCCTTATGACTCAACA
TTACCAATAAAGTGATGATCCTGGTCTGCGTTTATACATACGCTTGTTCGGTCCTGTTCCTGACACGTGGGTTGAGTCACCACAGCTCTG
TGTGGGGAACGTGGGAGACAGGAGTGGCTCCTGCCGGGGGAAGCTGGGCCTGCCATTGGCCCTGTGTCTATCATGAGGGGAGAGCTAAGA
AAGAAATTCTCCTAGGAAGAGCTCATGGCCCAGTACATCCTAGTAATTATTTTAATTAGTTTTTGTTCTGACAGCTTGTCAGGAAGGGCA
CAGAATGGGACAGAGATAAACCAGACAGTCATTTTGATCTGCTCTCTACGGTTTTTCAAGTCAGAGGCAATTGATGCTTGTCTAATGCAT
CCACACACTGCATGTCTGACTGGCGATGCCGCGCTCCTAAGTAGTTCTGCCATGAAACATAAAAGACAAAGGAAAAGCCGTTACACATCA
CACAGAGAACATTTTCGGGTCCCACAGCGGTGGTGGCAGGAAGCTCACTCTCGCGTCAGTATTAGAGTGTGTGTGTGGGTCTCGGGGATC
TCGGTGGCTCCCATCTTCCTTCATTGTTCTGAACATCCTGTATTGTAAACCATGGCTGGGGTGCTAAAGTGCCTGTGAATCCCGATGTGG
AAAAAGCTGGAGGTGAAAGCTCAGCATACCATGTATTTACTTTAAAAACAGAAAAAAAGACATGTATGGATATGTCTATTTTTTTTTTAT
TGGCACATTGTATTTTTGTGTTGACTTGTTTTTAGAAATGATGTGTCCACACACGTACCCGTGTCTCTTCTGCATTTCTGTGTCATGGTT
CTGTTTCTTAATCACGTGCGGCGGTGTCTAAGTGGTGTTACCAGTGTACGCGCAGTGACCTTGGATGACAGTGGCTCTTTCTCACAGCCT

>20659_20659_11_CUL2-PARD3_CUL2_chr10_35333494_ENST00000537177_PARD3_chr10_34806087_ENST00000374788_length(amino acids)=1550AA_BP=1
MNAVCRRKQQTLYFMYRVTWSTFWLRFQHYTCTMSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERL
YTETKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMW
RKLMVEPLQAILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYME
KLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSE
EPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASHPMVGKWLEKQEQDEDGTEEDNSRVEPV
GHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHM
FRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPS
APASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKS
QEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELNAEPSQMQIPKETKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKEN
HADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPI
ETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWA
KAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLGIADETKLNTVDDQKAGSPSRDVGPSLGLKK
SSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLER
QMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAK
TREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQR
LRQEFQQAKQDEDVEDRRRTYSFEQPWPNARPATQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSP
GEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVMLETQELLRQEQRRKEQQMKKQPPSEGPSNYDSYKKVQDPSYAPPKGPFRQDVPPSP

--------------------------------------------------------------
>20659_20659_12_CUL2-PARD3_CUL2_chr10_35333494_ENST00000537177_PARD3_chr10_34806087_ENST00000374789_length(transcript)=6290nt_BP=833nt
ATGTTGCAGTTGAGCCCAAACTGAATGCTGTCTGTAGAAGGAAACAACAAACTTTGTACTTTATGTACAGAGTAACATGGTCAACTTTTT
GGCTTAGATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACAA
TAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCTG
AACCCCTTGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAAG
AACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACCC
AGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGAG
AGCTAGCATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGATC
GTGGTGGAGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTAA
AGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCAA
ACTGCTCACAGTATATGGAAAAGCTGGTAGCAGTGTTTGATGAGCAGGATCCACATCACGGAGGTGATGGCACCAGTGCCAGTTCCACGG
GTACCCAGAGCCCAGAGATATTTGGTAGTGAGCTTGGCACCAACAATGTCTCAGCCTTTCAGCCTTACCAAGCAACAAGTGAAATTGAGG
TCACACCTTCAGTCCTTCGAGCAAATATGCCTCTTCATGTTCGACGCAGTAGTGACCCAGCTCTAATTGGCCTCTCCACTTCTGTCAGTG
ATAGTAATTTTTCCTCTGAAGAGCCTTCAAGGAAAAATCCCACACGCTGGTCAACAACAGCTGGCTTCCTCAAGCAGAACACTGCTGGGA
GTCCTAAAACCTGCGACAGGAAGAAAGATGAAAACTACAGAAGCCTCCCGCGGGATACTAGTAACTGGTCTAACCAATTTCAGAGAGACA
ATGCTCGCTCGTCTCTGAGTGCCAGTCACCCAATGGTGGGCAAGTGGCTGGAGAAACAAGAACAGGATGAGGATGGGACAGAAGAGGATA
ACAGTCGTGTTGAACCTGTTGGACATGCTGACACGGGTTTGGAGCATATACCCAACTTTTCTCTGGATGATATGGTAAAGCTCGTAGAAG
TCCCCAACGATGGAGGGCCTCTGGGAATCCACGTAGTGCCTTTCAGTGCTCGAGGCGGCAGAACCCTGGGGTTATTAGTAAAACGATTGG
AGAAAGGTGGTAAAGCTGAACATGAAAATCTTTTTCGTGAGAATGATTGCATTGTCAGGATTAATGATGGCGACCTTCGAAATAGAAGAT
TTGAACAAGCACAACATATGTTTCGCCAAGCCATGCGTACACCCATCATTTGGTTCCATGTGGTTCCTGCAGCAAATAAAGAGCAGTATG
AACAACTATCCCAAAGTGAGAAGAACAATTACTATTCAAGCCGTTTTAGCCCTGACAGCCAGTATATTGACAACAGGAGTGTGAACAGTG
CAGGGCTTCACACGGTGCAGAGAGCACCCCGACTGAACCACCCGCCTGAGCAGATAGACTCTCACTCAAGACTACCTCATAGCGCACACC
CCTCGGGAAAACCACCATCCGCTCCAGCCTCGGCACCTCAGAATGTATTTAGTACGACTGTAAGCAGTGGTTATAACACCAAAAAAATAG
GCAAGAGGCTTAATATCCAGCTTAAGAAAGGTACAGAAGGTTTGGGATTCAGCATCACTTCCAGAGATGTAACAATAGGTGGCTCAGCTC
CAATCTATGTGAAAAACATTCTCCCCCGGGGGGCGGCCATTCAGGATGGCCGACTTAAGGCAGGAGACAGACTTATAGAGGTAAATGGAG
TAGATTTAGTGGGCAAATCCCAAGAGGAAGTTGTTTCGCTGTTGAGAAGCACCAAGATGGAAGGAACTGTGAGCCTTCTGGTCTTTCGCC
AGGAAGACGCCTTCCACCCAAGGGAACTGAATGCAGAGCCAAGCCAGATGCAGATTCCAAAAGAAACGAAAGCAGAAGATGAGGATATTG
TTCTTACACCTGATGGCACCAGGGAATTTCTGACATTTGAAGTCCCACTTAATGATTCAGGATCTGCAGGCCTTGGTGTCAGTGTCAAAG
GTAACCGGTCAAAAGAGAACCACGCAGATTTGGGAATCTTTGTCAAGTCCATTATTAATGGAGGAGCAGCATCTAAAGATGGAAGGCTTC
GGGTGAATGATCAACTGATAGCAGTAAATGGAGAATCCCTGTTGGGCAAGACAAACCAAGATGCCATGGAAACCCTAAGAAGGTCTATGT
CTACTGAAGGCAATAAACGAGGAATGATCCAGCTTATTGTTGCAAGGAGAATAAGCAAGTGCAATGAGCTGAAGTCACCTGGGAGCCCCC
CTGGACCTGAGCTGCCCATTGAAACAGCGTTGGATGATAGAGAACGAAGAATTTCCCATTCCCTCTACAGTGGGATTGAGGGGCTTGATG
AATCGCCCAGCAGAAATGCTGCCCTCAGTAGGATAATGGGTGAGTCAGGTAAATACCAGCTGTCCCCTACAGTGAATATGCCCCAAGATG
ACACTGTCATTATAGAAGATGACAGGTTGCCAGTGCTTCCTCCACATCTCTCTGACCAGTCCTCTTCCAGCTCCCATGATGATGTGGGGT
TTGTGACGGCAGATGCTGGTACTTGGGCCAAGGCTGCAATCAGTGATTCAGCCGACTGCTCTTTGAGTCCAGATGTTGATCCAGTTCTTG
CTTTTCAACGAGAAGGATTTGGACGTCAGAGTATGTCAGAAAAACGCACAAAGCAATTTTCAGATGCCAGTCAATTGGATTTCGTTAAAA
CACGAAAATCAAAAAGCATGGATTTAGGTATAGCTGACGAGACTAAACTCAATACAGTGGATGACCAGAAAGCAGGTTCTCCCAGCAGAG
ATGTGGGTCCTTCCCTGGGTCTGAAGAAGTCAAGCTCGTTGGAGAGTCTGCAGACCGCAGTTGCCGAGGTGACTTTGAATGGGGATATTC
CTTTCCATCGTCCACGGCCGCGGATAATCAGAGGCAGGGGATGCAATGAGAGCTTCAGAGCTGCCATCGACAAATCTTATGATAAACCCG
CGGTAGATGATGATGATGAAGGCATGGAGACCTTGGAAGAAGACACAGAAGAAAGTTCAAGATCAGGGAGAGAGTCTGTATCCACAGCCA
GTGATCAGCCTTCCCACTCTCTGGAGAGACAAATGAATGGAAACCAAGAGAAAGGTGATAAGACTGATAGAAAAAAGGATAAAACTGGAA
AAGAAAAGAAGAAAGATAGAGATAAGGAGAAGGATAAAATGAAAGCCAAGAAGGGAATGCTGAAGGGCTTGGGAGACATGTTCAGGTTTG
GCAAACATCGAAAAGATGACAAGATTGAGAAAACGGGTAAAATAAAAATACAGGAATCCTTTACATCAGAAGAGGAGAGGATACGAATGA
AGCAGGAGCAGGAGAGGATTCAAGCCAAAACTCGAGAATTTAGGGAACGACAAGCTCGAGAGCGTGACTATGCTGAAATTCAAGATTTTC
ATCGGACATTTGGCTGTGATGATGAGTTAATGTATGGGGGAGTTTCTTCTTATGAAGGTTCCATGGCTCTCAACGCTAGACCTCAGAGCC
CACGAGAAGGGCATATGATGGATGCTTTGTATGCCCAAGTCAAGAAGCCGCGGAATTCCAAACCCTCACCTGTAGACAGTAACAGATCAA
CTCCTAGCAATCATGATCGGATACAGCGTCTGAGGCAAGAATTTCAGCAAGCAAAGCAAGATGAAGATGTAGAAGATCGTCGGCGGACCT
ATAGTTTTGAGCAACCCTGGCCGAACGCACGGCCGGCGACGCAGAGCGGGCGACACTCGGTGTCCGTGGAGGTGCAGATGCAGCGGCAGC
GGCAGGAGGAGCGCGAGAGCTCCCAGCAGGCCCAGCGCCAGTACAGCTCTCTGCCTCGGCAAAGCAGGAAAAATGCCAGCTCGGTCTCCC
AGGACTCTTGGGAGCAGAACTACTCCCCTGGGGAAGGCTTCCAGAGTGCCAAAGAGAACCCCAGGTACTCCAGCTACCAAGGCTCCAGGA
ACGGCTACCTGGGAGGACATGGCTTCAACGCCAGGGTCATGCTGGAAACTCAGGAGCTCCTTCGCCAGGAACAGAGGCGGAAGGAGCAGC
AGATGAAGAAGCAGCCTCCTTCCGAGGGGCCCAGCAACTATGACTCGTATAAGAAAGTCCAGGACCCCAGTTACGCCCCTCCCAAGGGGC
CCTTCCGGCAAGATGTGCCCCCCTCCCCTTCTCAGGTTGCGAGGCTGAACAGACTTCAGACTCCTGAGAAAGGGAGGCCCTTCTATTCCT
GAGCACGCAAATAACGGATGCTTCATGTCGCGCAATAAAAGACATTTTCCTATGAAGACTTGTATTTTGGGAGTTTTTTTAAAACCTCGA
TGGTACTATGGAGTATTTCTGTTGTTGGTATCAGTGCCTTTAAGCGGTGTAGGCAAAGAAATGGAAGGCCTTAATGTCTTTGCCACTATG
TCTCAAGTGTCTGTTTCATGGAAGGATTTCCCACCCTGTGACAATCATCTGTTTGAGGTGTTCATATGCTCTGCGCCTCTCCACAGTACC
AGGAATCTCGGCCCTACTCATGAGTTGTCCGCGGCTTGGTTGTAACATCCCTGCACCACTTGCAGTGACAAATTCACCTGAAGTGGAGGA
TGACGTGCGGCCCTGTTTCTCCCTCTAAGTTCTCTTAGCTATGGGATGACATCTTAGTCTCTGGTGGAGGAAAAGTGGGCGACATACACC
AAAAATTGGGGCTTTCTGGTACTTCACAGCACAGCCATTTGTCGTACTTTGTCATCACTGTGGTTTTCTCTTTCCTTTCTCAGCTCTTTG
TGACGGGAGAGTCGGTCATCCTATTACAGAAGCTAAGCCATAGTCCAACATTGTTTGGTCACCATGGGGGTCCTTTTGTAACTGCCTTAT
GACTCAACATTACCAATAAAGTGATGATCCTGGTCTGCGTTTATACATACGCTTGTTCGGTCCTGTTCCTGACACGTGGGTTGAGTCACC
ACAGCTCTGTGTGGGGAACGTGGGAGACAGGAGTGGCTCCTGCCGGGGGAAGCTGGGCCTGCCATTGGCCCTGTGTCTATCATGAGGGGA
GAGCTAAGAAAGAAATTCTCCTAGGAAGAGCTCATGGCCCAGTACATCCTAGTAATTATTTTAATTAGTTTTTGTTCTGACAGCTTGTCA
GGAAGGGCACAGAATGGGACAGAGATAAACCAGACAGTCATTTTGATCTGCTCTCTACGGTTTTTCAAGTCAGAGGCAATTGATGCTTGT
CTAATGCATCCACACACTGCATGTCTGACTGGCGATGCCGCGCTCCTAAGTAGTTCTGCCATGAAACATAAAAGACAAAGGAAAAGCCGT
TACACATCACACAGAGAACATTTTCGGGTCCCACAGCGGTGGTGGCAGGAAGCTCACTCTCGCGTCAGTATTAGAGTGTGTGTGTGGGTC
TCGGGGATCTCGGTGGCTCCCATCTTCCTTCATTGTTCTGAACATCCTGTATTGTAAACCATGGCTGGGGTGCTAAAGTGCCTGTGAATC
CCGATGTGGAAAAAGCTGGAGGTGAAAGCTCAGCATACCATGTATTTACTTTAAAAACAGAAAAAAAGACATGTATGGATATGTCTATTT
TTTTTTTATTGGCACATTGTATTTTTGTGTTGACTTGTTTTTAGAAATGATGTGTCCACACACGTACCCGTGTCTCTTCTGCATTTCTGT
GTCATGGTTCTGTTTCTTAATCACGTGCGGCGGTGTCTAAGTGGTGTTACCAGTGTACGCGCAGTGACCTTGGATGACAGTGGCTCTTTC

>20659_20659_12_CUL2-PARD3_CUL2_chr10_35333494_ENST00000537177_PARD3_chr10_34806087_ENST00000374789_length(amino acids)=1553AA_BP=1
MNAVCRRKQQTLYFMYRVTWSTFWLRFQHYTCTMSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERL
YTETKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMW
RKLMVEPLQAILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYME
KLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSE
EPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASHPMVGKWLEKQEQDEDGTEEDNSRVEPV
GHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHM
FRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPS
APASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKS
QEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELNAEPSQMQIPKETKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKEN
HADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPI
ETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGESGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAG
TWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLGIADETKLNTVDDQKAGSPSRDVGPSLG
LKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHS
LERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERI
QAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDR
IQRLRQEFQQAKQDEDVEDRRRTYSFEQPWPNARPATQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQN
YSPGEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVMLETQELLRQEQRRKEQQMKKQPPSEGPSNYDSYKKVQDPSYAPPKGPFRQDVP

--------------------------------------------------------------
>20659_20659_13_CUL2-PARD3_CUL2_chr10_35333494_ENST00000537177_PARD3_chr10_34806087_ENST00000374790_length(transcript)=6110nt_BP=833nt
ATGTTGCAGTTGAGCCCAAACTGAATGCTGTCTGTAGAAGGAAACAACAAACTTTGTACTTTATGTACAGAGTAACATGGTCAACTTTTT
GGCTTAGATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACAA
TAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCTG
AACCCCTTGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAAG
AACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACCC
AGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGAG
AGCTAGCATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGATC
GTGGTGGAGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTAA
AGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCAA
ACTGCTCACAGTATATGGAAAAGCTGGTAGCAGTGTTTGATGAGCAGGATCCACATCACGGAGGTGATGGCACCAGTGCCAGTTCCACGG
GTACCCAGAGCCCAGAGATATTTGGTAGTGAGCTTGGCACCAACAATGTCTCAGCCTTTCAGCCTTACCAAGCAACAAGTGAAATTGAGG
TCACACCTTCAGTCCTTCGAGCAAATATGCCTCTTCATGTTCGACGCAGTAGTGACCCAGCTCTAATTGGCCTCTCCACTTCTGTCAGTG
ATAGTAATTTTTCCTCTGAAGAGCCTTCAAGGAAAAATCCCACACGCTGGTCAACAACAGCTGGCTTCCTCAAGCAGAACACTGCTGGGA
GTCCTAAAACCTGCGACAGGAAGGATGAGGATGGGACAGAAGAGGATAACAGTCGTGTTGAACCTGTTGGACATGCTGACACGGGTTTGG
AGCATATACCCAACTTTTCTCTGGATGATATGGTAAAGCTCGTAGAAGTCCCCAACGATGGAGGGCCTCTGGGAATCCACGTAGTGCCTT
TCAGTGCTCGAGGCGGCAGAACCCTGGGGTTATTAGTAAAACGATTGGAGAAAGGTGGTAAAGCTGAACATGAAAATCTTTTTCGTGAGA
ATGATTGCATTGTCAGGATTAATGATGGCGACCTTCGAAATAGAAGATTTGAACAAGCACAACATATGTTTCGCCAAGCCATGCGTACAC
CCATCATTTGGTTCCATGTGGTTCCTGCAGCAAATAAAGAGCAGTATGAACAACTATCCCAAAGTGAGAAGAACAATTACTATTCAAGCC
GTTTTAGCCCTGACAGCCAGTATATTGACAACAGGAGTGTGAACAGTGCAGGGCTTCACACGGTGCAGAGAGCACCCCGACTGAACCACC
CGCCTGAGCAGATAGACTCTCACTCAAGACTACCTCATAGCGCACACCCCTCGGGAAAACCACCATCCGCTCCAGCCTCGGCACCTCAGA
ATGTATTTAGTACGACTGTAAGCAGTGGTTATAACACCAAAAAAATAGGCAAGAGGCTTAATATCCAGCTTAAGAAAGGTACAGAAGGTT
TGGGATTCAGCATCACTTCCAGAGATGTAACAATAGGTGGCTCAGCTCCAATCTATGTGAAAAACATTCTCCCCCGGGGGGCGGCCATTC
AGGATGGCCGACTTAAGGCAGGAGACAGACTTATAGAGGTAAATGGAGTAGATTTAGTGGGCAAATCCCAAGAGGAAGTTGTTTCGCTGT
TGAGAAGCACCAAGATGGAAGGAACTGTGAGCCTTCTGGTCTTTCGCCAGGAAGACGCCTTCCACCCAAGGGAACTGAAAGCAGAAGATG
AGGATATTGTTCTTACACCTGATGGCACCAGGGAATTTCTGACATTTGAAGTCCCACTTAATGATTCAGGATCTGCAGGCCTTGGTGTCA
GTGTCAAAGGTAACCGGTCAAAAGAGAACCACGCAGATTTGGGAATCTTTGTCAAGTCCATTATTAATGGAGGAGCAGCATCTAAAGATG
GAAGGCTTCGGGTGAATGATCAACTGATAGCAGTAAATGGAGAATCCCTGTTGGGCAAGACAAACCAAGATGCCATGGAAACCCTAAGAA
GGTCTATGTCTACTGAAGGCAATAAACGAGGAATGATCCAGCTTATTGTTGCAAGGAGAATAAGCAAGTGCAATGAGCTGAAGTCACCTG
GGAGCCCCCCTGGACCTGAGCTGCCCATTGAAACAGCGTTGGATGATAGAGAACGAAGAATTTCCCATTCCCTCTACAGTGGGATTGAGG
GGCTTGATGAATCGCCCAGCAGAAATGCTGCCCTCAGTAGGATAATGGGTAAATACCAGCTGTCCCCTACAGTGAATATGCCCCAAGATG
ACACTGTCATTATAGAAGATGACAGGTTGCCAGTGCTTCCTCCACATCTCTCTGACCAGTCCTCTTCCAGCTCCCATGATGATGTGGGGT
TTGTGACGGCAGATGCTGGTACTTGGGCCAAGGCTGCAATCAGTGATTCAGCCGACTGCTCTTTGAGTCCAGATGTTGATCCAGTTCTTG
CTTTTCAACGAGAAGGATTTGGACGTCAGAGTATGTCAGAAAAACGCACAAAGCAATTTTCAGATGCCAGTCAATTGGATTTCGTTAAAA
CACGAAAATCAAAAAGCATGGATTTAGGTATAGCTGACGAGACTAAACTCAATACAGTGGATGACCAGAAAGCAGGTTCTCCCAGCAGAG
ATGTGGGTCCTTCCCTGGGTCTGAAGAAGTCAAGCTCGTTGGAGAGTCTGCAGACCGCAGTTGCCGAGGTGACTTTGAATGGGGATATTC
CTTTCCATCGTCCACGGCCGCGGATAATCAGAGGCAGGGGATGCAATGAGAGCTTCAGAGCTGCCATCGACAAATCTTATGATAAACCCG
CGGTAGATGATGATGATGAAGGCATGGAGACCTTGGAAGAAGACACAGAAGAAAGTTCAAGATCAGGGAGAGAGTCTGTATCCACAGCCA
GTGATCAGCCTTCCCACTCTCTGGAGAGACAAATGAATGGAAACCAAGAGAAAGGTGATAAGACTGATAGAAAAAAGGATAAAACTGGAA
AAGAAAAGAAGAAAGATAGAGATAAGGAGAAGGATAAAATGAAAGCCAAGAAGGGAATGCTGAAGGGCTTGGGAGACATGTTCAGGTTTG
GCAAACATCGAAAAGATGACAAGATTGAGAAAACGGGTAAAATAAAAATACAGGAATCCTTTACATCAGAAGAGGAGAGGATACGAATGA
AGCAGGAGCAGGAGAGGATTCAAGCCAAAACTCGAGAATTTAGGGAACGACAAGCTCGAGAGCGTGACTATGCTGAAATTCAAGATTTTC
ATCGGACATTTGGCTGTGATGATGAGTTAATGTATGGGGGAGTTTCTTCTTATGAAGGTTCCATGGCTCTCAACGCTAGACCTCAGAGCC
CACGAGAAGGGCATATGATGGATGCTTTGTATGCCCAAGTCAAGAAGCCGCGGAATTCCAAACCCTCACCTGTAGACAGTAACAGATCAA
CTCCTAGCAATCATGATCGGATACAGCGTCTGAGGCAAGAATTTCAGCAAGCAAAGCAAGATGAAGATGTAGAAGATCGTCGGCGGACCT
ATAGTTTTGAGCAACCCTGGCCGAACGCACGGCCGGCGACGCAGAGCGGGCGACACTCGGTGTCCGTGGAGGTGCAGATGCAGCGGCAGC
GGCAGGAGGAGCGCGAGAGCTCCCAGCAGGCCCAGCGCCAGTACAGCTCTCTGCCTCGGCAAAGCAGGAAAAATGCCAGCTCGGTCTCCC
AGGACTCTTGGGAGCAGAACTACTCCCCTGGGGAAGGCTTCCAGAGTGCCAAAGAGAACCCCAGGTACTCCAGCTACCAAGGCTCCAGGA
ACGGCTACCTGGGAGGACATGGCTTCAACGCCAGGGTCATGCTGGAAACTCAGGAGCTCCTTCGCCAGGAACAGAGGCGGAAGGAGCAGC
AGATGAAGAAGCAGCCTCCTTCCGAGGGGCCCAGCAACTATGACTCGTATAAGAAAGTCCAGGACCCCAGTTACGCCCCTCCCAAGGGGC
CCTTCCGGCAAGATGTGCCCCCCTCCCCTTCTCAGGTTGCGAGGCTGAACAGACTTCAGACTCCTGAGAAAGGGAGGCCCTTCTATTCCT
GAGCACGCAAATAACGGATGCTTCATGTCGCGCAATAAAAGACATTTTCCTATGAAGACTTGTATTTTGGGAGTTTTTTTAAAACCTCGA
TGGTACTATGGAGTATTTCTGTTGTTGGTATCAGTGCCTTTAAGCGGTGTAGGCAAAGAAATGGAAGGCCTTAATGTCTTTGCCACTATG
TCTCAAGTGTCTGTTTCATGGAAGGATTTCCCACCCTGTGACAATCATCTGTTTGAGGTGTTCATATGCTCTGCGCCTCTCCACAGTACC
AGGAATCTCGGCCCTACTCATGAGTTGTCCGCGGCTTGGTTGTAACATCCCTGCACCACTTGCAGTGACAAATTCACCTGAAGTGGAGGA
TGACGTGCGGCCCTGTTTCTCCCTCTAAGTTCTCTTAGCTATGGGATGACATCTTAGTCTCTGGTGGAGGAAAAGTGGGCGACATACACC
AAAAATTGGGGCTTTCTGGTACTTCACAGCACAGCCATTTGTCGTACTTTGTCATCACTGTGGTTTTCTCTTTCCTTTCTCAGCTCTTTG
TGACGGGAGAGTCGGTCATCCTATTACAGAAGCTAAGCCATAGTCCAACATTGTTTGGTCACCATGGGGGTCCTTTTGTAACTGCCTTAT
GACTCAACATTACCAATAAAGTGATGATCCTGGTCTGCGTTTATACATACGCTTGTTCGGTCCTGTTCCTGACACGTGGGTTGAGTCACC
ACAGCTCTGTGTGGGGAACGTGGGAGACAGGAGTGGCTCCTGCCGGGGGAAGCTGGGCCTGCCATTGGCCCTGTGTCTATCATGAGGGGA
GAGCTAAGAAAGAAATTCTCCTAGGAAGAGCTCATGGCCCAGTACATCCTAGTAATTATTTTAATTAGTTTTTGTTCTGACAGCTTGTCA
GGAAGGGCACAGAATGGGACAGAGATAAACCAGACAGTCATTTTGATCTGCTCTCTACGGTTTTTCAAGTCAGAGGCAATTGATGCTTGT
CTAATGCATCCACACACTGCATGTCTGACTGGCGATGCCGCGCTCCTAAGTAGTTCTGCCATGAAACATAAAAGACAAAGGAAAAGCCGT
TACACATCACACAGAGAACATTTTCGGGTCCCACAGCGGTGGTGGCAGGAAGCTCACTCTCGCGTCAGTATTAGAGTGTGTGTGTGGGTC
TCGGGGATCTCGGTGGCTCCCATCTTCCTTCATTGTTCTGAACATCCTGTATTGTAAACCATGGCTGGGGTGCTAAAGTGCCTGTGAATC
CCGATGTGGAAAAAGCTGGAGGTGAAAGCTCAGCATACCATGTATTTACTTTAAAAACAGAAAAAAAGACATGTATGGATATGTCTATTT
TTTTTTTATTGGCACATTGTATTTTTGTGTTGACTTGTTTTTAGAAATGATGTGTCCACACACGTACCCGTGTCTCTTCTGCATTTCTGT
GTCATGGTTCTGTTTCTTAATCACGTGCGGCGGTGTCTAAGTGGTGTTACCAGTGTACGCGCAGTGACCTTGGATGACAGTGGCTCTTTC

>20659_20659_13_CUL2-PARD3_CUL2_chr10_35333494_ENST00000537177_PARD3_chr10_34806087_ENST00000374790_length(amino acids)=1493AA_BP=1
MNAVCRRKQQTLYFMYRVTWSTFWLRFQHYTCTMSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERL
YTETKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMW
RKLMVEPLQAILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYME
KLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSE
EPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGR
TLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQ
YIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITS
RDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELKAEDEDIVLTP
DGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEG
NKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGKYQLSPTVNMPQDDTVIIED
DRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSM
DLGIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDE
GMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDD
KIEKTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMM
DALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRRTYSFEQPWPNARPATQSGRHSVSVEVQMQRQRQEERES
SQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSPGEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVMLETQELLRQEQRRKEQQMKKQPP

--------------------------------------------------------------
>20659_20659_14_CUL2-PARD3_CUL2_chr10_35333494_ENST00000537177_PARD3_chr10_34806087_ENST00000374794_length(transcript)=5954nt_BP=833nt
ATGTTGCAGTTGAGCCCAAACTGAATGCTGTCTGTAGAAGGAAACAACAAACTTTGTACTTTATGTACAGAGTAACATGGTCAACTTTTT
GGCTTAGATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACAA
TAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCTG
AACCCCTTGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAAG
AACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACCC
AGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGAG
AGCTAGCATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGATC
GTGGTGGAGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTAA
AGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCAA
ACTGCTCACAGTATATGGAAAAGCTGGTAGCAGTGTTTGATGAGCAGGATCCACATCACGGAGGTGATGGCACCAGTGCCAGTTCCACGG
GTACCCAGAGCCCAGAGATATTTGGTAGTGAGCTTGGCACCAACAATGTCTCAGCCTTTCAGCCTTACCAAGCAACAAGTGAAATTGAGG
TCACACCTTCAGTCCTTCGAGCAAATATGCCTCTTCATGTTCGACGCAGTAGTGACCCAGCTCTAATTGGCCTCTCCACTTCTGTCAGTG
ATAGTAATTTTTCCTCTGAAGAGCCTTCAAGGAAAAATCCCACACGCTGGTCAACAACAGCTGGCTTCCTCAAGCAGAACACTGCTGGGA
GTCCTAAAACCTGCGACAGGAAGGATGAGGATGGGACAGAAGAGGATAACAGTCGTGTTGAACCTGTTGGACATGCTGACACGGGTTTGG
AGCATATACCCAACTTTTCTCTGGATGATATGGTAAAGCTCGTAGAAGTCCCCAACGATGGAGGGCCTCTGGGAATCCACGTAGTGCCTT
TCAGTGCTCGAGGCGGCAGAACCCTGGGGTTATTAGTAAAACGATTGGAGAAAGGTGGTAAAGCTGAACATGAAAATCTTTTTCGTGAGA
ATGATTGCATTGTCAGGATTAATGATGGCGACCTTCGAAATAGAAGATTTGAACAAGCACAACATATGTTTCGCCAAGCCATGCGTACAC
CCATCATTTGGTTCCATGTGGTTCCTGCAGCAAATAAAGAGCAGTATGAACAACTATCCCAAAGTGAGAAGAACAATTACTATTCAAGCC
GTTTTAGCCCTGACAGCCAGTATATTGACAACAGGAGTGTGAACAGTGCAGGGCTTCACACGGTGCAGAGAGCACCCCGACTGAACCACC
CGCCTGAGCAGATAGACTCTCACTCAAGACTACCTCATAGCGCACACCCCTCGGGAAAACCACCATCCGCTCCAGCCTCGGCACCTCAGA
ATGTATTTAGTACGACTGTAAGCAGTGGTTATAACACCAAAAAAATAGGCAAGAGGCTTAATATCCAGCTTAAGAAAGGTACAGAAGGTT
TGGGATTCAGCATCACTTCCAGAGATGTAACAATAGGTGGCTCAGCTCCAATCTATGTGAAAAACATTCTCCCCCGGGGGGCGGCCATTC
AGGATGGCCGACTTAAGGCAGGAGACAGACTTATAGAGGTAAATGGAGTAGATTTAGTGGGCAAATCCCAAGAGGAAGTTGTTTCGCTGT
TGAGAAGCACCAAGATGGAAGGAACTGTGAGCCTTCTGGTCTTTCGCCAGGAAGACGCCTTCCACCCAAGGGAACTGAAAGCAGAAGATG
AGGATATTGTTCTTACACCTGATGGCACCAGGGAATTTCTGACATTTGAAGTCCCACTTAATGATTCAGGATCTGCAGGCCTTGGTGTCA
GTGTCAAAGGTAACCGGTCAAAAGAGAACCACGCAGATTTGGGAATCTTTGTCAAGTCCATTATTAATGGAGGAGCAGCATCTAAAGATG
GAAGGCTTCGGGTGAATGATCAACTGATAGCAGTAAATGGAGAATCCCTGTTGGGCAAGACAAACCAAGATGCCATGGAAACCCTAAGAA
GGTCTATGTCTACTGAAGGCAATAAACGAGGAATGATCCAGCTTATTGTTGCAAGGAGAATAAGCAAGTGCAATGAGCTGAAGTCACCTG
GGAGCCCCCCTGGACCTGAGCTGCCCATTGAAACAGCGTTGGATGATAGAGAACGAAGAATTTCCCATTCCCTCTACAGTGGGATTGAGG
GGCTTGATGAATCGCCCAGCAGAAATGCTGCCCTCAGTAGGATAATGGGTAAATACCAGCTGTCCCCTACAGTGAATATGCCCCAAGATG
ACACTGTCATTATAGAAGATGACAGGTTGCCAGTGCTTCCTCCACATCTCTCTGACCAGTCCTCTTCCAGCTCCCATGATGATGTGGGGT
TTGTGACGGCAGATGCTGGTACTTGGGCCAAGGCTGCAATCAGTGATTCAGCCGACTGCTCTTTGAGTCCAGATGTTGATCCAGTTCTTG
CTTTTCAACGAGAAGGATTTGGACGTCAGAGTATGTCAGAAAAACGCACAAAGCAATTTTCAGATGCCAGTCAATTGGATTTCGTTAAAA
CACGAAAATCAAAAAGCATGGATTTAGGTAGTTCTCCCAGCAGAGATGTGGGTCCTTCCCTGGGTCTGAAGAAGTCAAGCTCGTTGGAGA
GTCTGCAGACCGCAGTTGCCGAGGTGACTTTGAATGGGGATATTCCTTTCCATCGTCCACGGCCGCGGATAATCAGAGGCAGGGGATGCA
ATGAGAGCTTCAGAGCTGCCATCGACAAATCTTATGATAAACCCGCGGTAGATGATGATGATGAAGGCATGGAGACCTTGGAAGAAGACA
CAGAAGAAAGTTCAAGATCAGGGAGAGAGTCTGTATCCACAGCCAGTGATCAGCCTTCCCACTCTCTGGAGAGACAAATGAATGGAAACC
AAGAGAAAGGTGATAAGACTGATAGAAAAAAGGATAAAACTGGAAAAGAAAAGAAGAAAGATAGAGATAAGGAGAAGGATAAAATGAAAG
CCAAGAAGGGAATGCTGAAGGGCTTGGGAGACATGTTCAGGATTCAAGCCAAAACTCGAGAATTTAGGGAACGACAAGCTCGAGAGCGTG
ACTATGCTGAAATTCAAGATTTTCATCGGACATTTGGCTGTGATGATGAGTTAATGTATGGGGGAGTTTCTTCTTATGAAGGTTCCATGG
CTCTCAACGCTAGACCTCAGAGCCCACGAGAAGGGCATATGATGGATGCTTTGTATGCCCAAGTCAAGAAGCCGCGGAATTCCAAACCCT
CACCTGTAGACAGTAACAGATCAACTCCTAGCAATCATGATCGGATACAGCGTCTGAGGCAAGAATTTCAGCAAGCAAAGCAAGATGAAG
ATGTAGAAGATCGTCGGCGGACCTATAGTTTTGAGCAACCCTGGCCGAACGCACGGCCGGCGACGCAGAGCGGGCGACACTCGGTGTCCG
TGGAGGTGCAGATGCAGCGGCAGCGGCAGGAGGAGCGCGAGAGCTCCCAGCAGGCCCAGCGCCAGTACAGCTCTCTGCCTCGGCAAAGCA
GGAAAAATGCCAGCTCGGTCTCCCAGGACTCTTGGGAGCAGAACTACTCCCCTGGGGAAGGCTTCCAGAGTGCCAAAGAGAACCCCAGGT
ACTCCAGCTACCAAGGCTCCAGGAACGGCTACCTGGGAGGACATGGCTTCAACGCCAGGGTCATGCTGGAAACTCAGGAGCTCCTTCGCC
AGGAACAGAGGCGGAAGGAGCAGCAGATGAAGAAGCAGCCTCCTTCCGAGGGGCCCAGCAACTATGACTCGTATAAGAAAGTCCAGGACC
CCAGTTACGCCCCTCCCAAGGGGCCCTTCCGGCAAGATGTGCCCCCCTCCCCTTCTCAGGTTGCGAGGCTGAACAGACTTCAGACTCCTG
AGAAAGGGAGGCCCTTCTATTCCTGAGCACGCAAATAACGGATGCTTCATGTCGCGCAATAAAAGACATTTTCCTATGAAGACTTGTATT
TTGGGAGTTTTTTTAAAACCTCGATGGTACTATGGAGTATTTCTGTTGTTGGTATCAGTGCCTTTAAGCGGTGTAGGCAAAGAAATGGAA
GGCCTTAATGTCTTTGCCACTATGTCTCAAGTGTCTGTTTCATGGAAGGATTTCCCACCCTGTGACAATCATCTGTTTGAGGTGTTCATA
TGCTCTGCGCCTCTCCACAGTACCAGGAATCTCGGCCCTACTCATGAGTTGTCCGCGGCTTGGTTGTAACATCCCTGCACCACTTGCAGT
GACAAATTCACCTGAAGTGGAGGATGACGTGCGGCCCTGTTTCTCCCTCTAAGTTCTCTTAGCTATGGGATGACATCTTAGTCTCTGGTG
GAGGAAAAGTGGGCGACATACACCAAAAATTGGGGCTTTCTGGTACTTCACAGCACAGCCATTTGTCGTACTTTGTCATCACTGTGGTTT
TCTCTTTCCTTTCTCAGCTCTTTGTGACGGGAGAGTCGGTCATCCTATTACAGAAGCTAAGCCATAGTCCAACATTGTTTGGTCACCATG
GGGGTCCTTTTGTAACTGCCTTATGACTCAACATTACCAATAAAGTGATGATCCTGGTCTGCGTTTATACATACGCTTGTTCGGTCCTGT
TCCTGACACGTGGGTTGAGTCACCACAGCTCTGTGTGGGGAACGTGGGAGACAGGAGTGGCTCCTGCCGGGGGAAGCTGGGCCTGCCATT
GGCCCTGTGTCTATCATGAGGGGAGAGCTAAGAAAGAAATTCTCCTAGGAAGAGCTCATGGCCCAGTACATCCTAGTAATTATTTTAATT
AGTTTTTGTTCTGACAGCTTGTCAGGAAGGGCACAGAATGGGACAGAGATAAACCAGACAGTCATTTTGATCTGCTCTCTACGGTTTTTC
AAGTCAGAGGCAATTGATGCTTGTCTAATGCATCCACACACTGCATGTCTGACTGGCGATGCCGCGCTCCTAAGTAGTTCTGCCATGAAA
CATAAAAGACAAAGGAAAAGCCGTTACACATCACACAGAGAACATTTTCGGGTCCCACAGCGGTGGTGGCAGGAAGCTCACTCTCGCGTC
AGTATTAGAGTGTGTGTGTGGGTCTCGGGGATCTCGGTGGCTCCCATCTTCCTTCATTGTTCTGAACATCCTGTATTGTAAACCATGGCT
GGGGTGCTAAAGTGCCTGTGAATCCCGATGTGGAAAAAGCTGGAGGTGAAAGCTCAGCATACCATGTATTTACTTTAAAAACAGAAAAAA
AGACATGTATGGATATGTCTATTTTTTTTTTATTGGCACATTGTATTTTTGTGTTGACTTGTTTTTAGAAATGATGTGTCCACACACGTA
CCCGTGTCTCTTCTGCATTTCTGTGTCATGGTTCTGTTTCTTAATCACGTGCGGCGGTGTCTAAGTGGTGTTACCAGTGTACGCGCAGTG
ACCTTGGATGACAGTGGCTCTTTCTCACAGCCTCCCCTGAGCTGTGAGAAACAGCTTTCTCTGTACATATGCAACTCCTAATAAAAGGCA

>20659_20659_14_CUL2-PARD3_CUL2_chr10_35333494_ENST00000537177_PARD3_chr10_34806087_ENST00000374794_length(amino acids)=1441AA_BP=1
MNAVCRRKQQTLYFMYRVTWSTFWLRFQHYTCTMSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERL
YTETKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMW
RKLMVEPLQAILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYME
KLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSE
EPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGR
TLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQ
YIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITS
RDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELKAEDEDIVLTP
DGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEG
NKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGKYQLSPTVNMPQDDTVIIED
DRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSM
DLGSSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRS
GRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRIQAKTREFRERQARERDYAEIQD
FHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRR
TYSFEQPWPNARPATQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSPGEGFQSAKENPRYSSYQGS
RNGYLGGHGFNARVMLETQELLRQEQRRKEQQMKKQPPSEGPSNYDSYKKVQDPSYAPPKGPFRQDVPPSPSQVARLNRLQTPEKGRPFY

--------------------------------------------------------------
>20659_20659_15_CUL2-PARD3_CUL2_chr10_35333494_ENST00000537177_PARD3_chr10_34806087_ENST00000545260_length(transcript)=6021nt_BP=833nt
ATGTTGCAGTTGAGCCCAAACTGAATGCTGTCTGTAGAAGGAAACAACAAACTTTGTACTTTATGTACAGAGTAACATGGTCAACTTTTT
GGCTTAGATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACAA
TAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCTG
AACCCCTTGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAAG
AACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACCC
AGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGAG
AGCTAGCATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGATC
GTGGTGGAGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTAA
AGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCAA
ACTGCTCACAGTATATGGAAAAGCTGGTAGCAGTGTTTGATGAGCAGGATCCACATCACGGAGGTGATGGCACCAGTGCCAGTTCCACGG
GTACCCAGAGCCCAGAGATATTTGGTAGTGAGCTTGGCACCAACAATGTCTCAGCCTTTCAGCCTTACCAAGCAACAAGTGAAATTGAGG
TCACACCTTCAGTCCTTCGAGCAAATATGCCTCTTCATGTTCGACGCAGTAGTGACCCAGCTCTAATTGGCCTCTCCACTTCTGTCAGTG
ATAGTAATTTTTCCTCTGAAGAGCCTTCAAGGAAAAATCCCACACGCTGGTCAACAACAGCTGGCTTCCTCAAGCAGAACACTGCTGGGA
GTCCTAAAACCTGCGACAGGAAGGATGAGGATGGGACAGAAGAGGATAACAGTCGTGTTGAACCTGTTGGACATGCTGACACGGGTTTGG
AGCATATACCCAACTTTTCTCTGGATGATATGGTAAAGCTCGTAGAAGTCCCCAACGATGGAGGGCCTCTGGGAATCCACGTAGTGCCTT
TCAGTGCTCGAGGCGGCAGAACCCTGGGGTTATTAGTAAAACGATTGGAGAAAGGTGGTAAAGCTGAACATGAAAATCTTTTTCGTGAGA
ATGATTGCATTGTCAGGATTAATGATGGCGACCTTCGAAATAGAAGATTTGAACAAGCACAACATATGTTTCGCCAAGCCATGCGTACAC
CCATCATTTGGTTCCATGTGGTTCCTGCAGCAAATAAAGAGCAGTATGAACAACTATCCCAAAGTGAGAAGAACAATTACTATTCAAGCC
GTTTTAGCCCTGACAGCCAGTATATTGACAACAGGAGTGTGAACAGTGCAGGGCTTCACACGGTGCAGAGAGCACCCCGACTGAACCACC
CGCCTGAGCAGATAGACTCTCACTCAAGACTACCTCATAGCGCACACCCCTCGGGAAAACCACCATCCGCTCCAGCCTCGGCACCTCAGA
ATGTATTTAGTACGACTGTAAGCAGTGGTTATAACACCAAAAAAATAGGCAAGAGGCTTAATATCCAGCTTAAGAAAGGTACAGAAGGTT
TGGGATTCAGCATCACTTCCAGAGATGTAACAATAGGTGGCTCAGCTCCAATCTATGTGAAAAACATTCTCCCCCGGGGGGCGGCCATTC
AGGATGGCCGACTTAAGGCAGGAGACAGACTTATAGAGGTAAATGGAGTAGATTTAGTGGGCAAATCCCAAGAGGAAGTTGTTTCGCTGT
TGAGAAGCACCAAGATGGAAGGAACTGTGAGCCTTCTGGTCTTTCGCCAGGAAGACGCCTTCCACCCAAGGGAACTGAAAGCAGAAGATG
AGGATATTGTTCTTACACCTGATGGCACCAGGGAATTTCTGACATTTGAAGTCCCACTTAATGATTCAGGATCTGCAGGCCTTGGTGTCA
GTGTCAAAGGTAACCGGTCAAAAGAGAACCACGCAGATTTGGGAATCTTTGTCAAGTCCATTATTAATGGAGGAGCAGCATCTAAAGATG
GAAGGCTTCGGGTGAATGATCAACTGATAGCAGTAAATGGAGAATCCCTGTTGGGCAAGACAAACCAAGATGCCATGGAAACCCTAAGAA
GGTCTATGTCTACTGAAGGCAATAAACGAGGAATGATCCAGCTTATTGTTGCAAGGAGAATAAGCAAGTGCAATGAGCTGAAGTCACCTG
GGAGCCCCCCTGGACCTGAGCTGCCCATTGAAACAGCGTTGGATGATAGAGAACGAAGAATTTCCCATTCCCTCTACAGTGGGATTGAGG
GGCTTGATGAATCGCCCAGCAGAAATGCTGCCCTCAGTAGGATAATGGGTAAATACCAGCTGTCCCCTACAGTGAATATGCCCCAAGATG
ACACTGTCATTATAGAAGATGACAGGTTGCCAGTGCTTCCTCCACATCTCTCTGACCAGTCCTCTTCCAGCTCCCATGATGATGTGGGGT
TTGTGACGGCAGATGCTGGTACTTGGGCCAAGGCTGCAATCAGTGATTCAGCCGACTGCTCTTTGAGTCCAGATGTTGATCCAGTTCTTG
CTTTTCAACGAGAAGGATTTGGACGTCAGATAGCTGACGAGACTAAACTCAATACAGTGGATGACCAGAAAGCAGGTTCTCCCAGCAGAG
ATGTGGGTCCTTCCCTGGGTCTGAAGAAGTCAAGCTCGTTGGAGAGTCTGCAGACCGCAGTTGCCGAGGTGACTTTGAATGGGGATATTC
CTTTCCATCGTCCACGGCCGCGGATAATCAGAGGCAGGGGATGCAATGAGAGCTTCAGAGCTGCCATCGACAAATCTTATGATAAACCCG
CGGTAGATGATGATGATGAAGGCATGGAGACCTTGGAAGAAGACACAGAAGAAAGTTCAAGATCAGGGAGAGAGTCTGTATCCACAGCCA
GTGATCAGCCTTCCCACTCTCTGGAGAGACAAATGAATGGAAACCAAGAGAAAGGTGATAAGACTGATAGAAAAAAGGATAAAACTGGAA
AAGAAAAGAAGAAAGATAGAGATAAGGAGAAGGATAAAATGAAAGCCAAGAAGGGAATGCTGAAGGGCTTGGGAGACATGTTCAGGTTTG
GCAAACATCGAAAAGATGACAAGATTGAGAAAACGGGTAAAATAAAAATACAGGAATCCTTTACATCAGAAGAGGAGAGGATACGAATGA
AGCAGGAGCAGGAGAGGATTCAAGCCAAAACTCGAGAATTTAGGGAACGACAAGCTCGAGAGCGTGACTATGCTGAAATTCAAGATTTTC
ATCGGACATTTGGCTGTGATGATGAGTTAATGTATGGGGGAGTTTCTTCTTATGAAGGTTCCATGGCTCTCAACGCTAGACCTCAGAGCC
CACGAGAAGGGCATATGATGGATGCTTTGTATGCCCAAGTCAAGAAGCCGCGGAATTCCAAACCCTCACCTGTAGACAGTAACAGATCAA
CTCCTAGCAATCATGATCGGATACAGCGTCTGAGGCAAGAATTTCAGCAAGCAAAGCAAGATGAAGATGTAGAAGATCGTCGGCGGACCT
ATAGTTTTGAGCAACCCTGGCCGAACGCACGGCCGGCGACGCAGAGCGGGCGACACTCGGTGTCCGTGGAGGTGCAGATGCAGCGGCAGC
GGCAGGAGGAGCGCGAGAGCTCCCAGCAGGCCCAGCGCCAGTACAGCTCTCTGCCTCGGCAAAGCAGGAAAAATGCCAGCTCGGTCTCCC
AGGACTCTTGGGAGCAGAACTACTCCCCTGGGGAAGGCTTCCAGAGTGCCAAAGAGAACCCCAGGTACTCCAGCTACCAAGGCTCCAGGA
ACGGCTACCTGGGAGGACATGGCTTCAACGCCAGGGTCATGCTGGAAACTCAGGAGCTCCTTCGCCAGGAACAGAGGCGGAAGGAGCAGC
AGATGAAGAAGCAGCCTCCTTCCGAGGGGCCCAGCAACTATGACTCGTATAAGAAAGTCCAGGACCCCAGTTACGCCCCTCCCAAGGGGC
CCTTCCGGCAAGATGTGCCCCCCTCCCCTTCTCAGGTTGCGAGGCTGAACAGACTTCAGACTCCTGAGAAAGGGAGGCCCTTCTATTCCT
GAGCACGCAAATAACGGATGCTTCATGTCGCGCAATAAAAGACATTTTCCTATGAAGACTTGTATTTTGGGAGTTTTTTTAAAACCTCGA
TGGTACTATGGAGTATTTCTGTTGTTGGTATCAGTGCCTTTAAGCGGTGTAGGCAAAGAAATGGAAGGCCTTAATGTCTTTGCCACTATG
TCTCAAGTGTCTGTTTCATGGAAGGATTTCCCACCCTGTGACAATCATCTGTTTGAGGTGTTCATATGCTCTGCGCCTCTCCACAGTACC
AGGAATCTCGGCCCTACTCATGAGTTGTCCGCGGCTTGGTTGTAACATCCCTGCACCACTTGCAGTGACAAATTCACCTGAAGTGGAGGA
TGACGTGCGGCCCTGTTTCTCCCTCTAAGTTCTCTTAGCTATGGGATGACATCTTAGTCTCTGGTGGAGGAAAAGTGGGCGACATACACC
AAAAATTGGGGCTTTCTGGTACTTCACAGCACAGCCATTTGTCGTACTTTGTCATCACTGTGGTTTTCTCTTTCCTTTCTCAGCTCTTTG
TGACGGGAGAGTCGGTCATCCTATTACAGAAGCTAAGCCATAGTCCAACATTGTTTGGTCACCATGGGGGTCCTTTTGTAACTGCCTTAT
GACTCAACATTACCAATAAAGTGATGATCCTGGTCTGCGTTTATACATACGCTTGTTCGGTCCTGTTCCTGACACGTGGGTTGAGTCACC
ACAGCTCTGTGTGGGGAACGTGGGAGACAGGAGTGGCTCCTGCCGGGGGAAGCTGGGCCTGCCATTGGCCCTGTGTCTATCATGAGGGGA
GAGCTAAGAAAGAAATTCTCCTAGGAAGAGCTCATGGCCCAGTACATCCTAGTAATTATTTTAATTAGTTTTTGTTCTGACAGCTTGTCA
GGAAGGGCACAGAATGGGACAGAGATAAACCAGACAGTCATTTTGATCTGCTCTCTACGGTTTTTCAAGTCAGAGGCAATTGATGCTTGT
CTAATGCATCCACACACTGCATGTCTGACTGGCGATGCCGCGCTCCTAAGTAGTTCTGCCATGAAACATAAAAGACAAAGGAAAAGCCGT
TACACATCACACAGAGAACATTTTCGGGTCCCACAGCGGTGGTGGCAGGAAGCTCACTCTCGCGTCAGTATTAGAGTGTGTGTGTGGGTC
TCGGGGATCTCGGTGGCTCCCATCTTCCTTCATTGTTCTGAACATCCTGTATTGTAAACCATGGCTGGGGTGCTAAAGTGCCTGTGAATC
CCGATGTGGAAAAAGCTGGAGGTGAAAGCTCAGCATACCATGTATTTACTTTAAAAACAGAAAAAAAGACATGTATGGATATGTCTATTT
TTTTTTTATTGGCACATTGTATTTTTGTGTTGACTTGTTTTTAGAAATGATGTGTCCACACACGTACCCGTGTCTCTTCTGCATTTCTGT
GTCATGGTTCTGTTTCTTAATCACGTGCGGCGGTGTCTAAGTGGTGTTACCAGTGTACGCGCAGTGACCTTGGATGACAGTGGCTCTTTC

>20659_20659_15_CUL2-PARD3_CUL2_chr10_35333494_ENST00000537177_PARD3_chr10_34806087_ENST00000545260_length(amino acids)=1463AA_BP=1
MNAVCRRKQQTLYFMYRVTWSTFWLRFQHYTCTMSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERL
YTETKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMW
RKLMVEPLQAILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYME
KLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSE
EPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGR
TLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQ
YIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITS
RDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELKAEDEDIVLTP
DGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEG
NKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGKYQLSPTVNMPQDDTVIIED
DRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQIADETKLNTVDDQKAGSPSRDVGPSLG
LKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHS
LERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERI
QAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDR
IQRLRQEFQQAKQDEDVEDRRRTYSFEQPWPNARPATQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQN
YSPGEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVMLETQELLRQEQRRKEQQMKKQPPSEGPSNYDSYKKVQDPSYAPPKGPFRQDVP

--------------------------------------------------------------
>20659_20659_16_CUL2-PARD3_CUL2_chr10_35333494_ENST00000537177_PARD3_chr10_34806087_ENST00000545693_length(transcript)=6243nt_BP=833nt
ATGTTGCAGTTGAGCCCAAACTGAATGCTGTCTGTAGAAGGAAACAACAAACTTTGTACTTTATGTACAGAGTAACATGGTCAACTTTTT
GGCTTAGATTTCAACACTACACTTGCACAATGTCTTTGAAACCAAGAGTAGTAGATTTTGATGAAACATGGAACAAACTTTTGACGACAA
TAAAAGCCGTGGTCATGTTGGAATACGTCGAAAGAGCAACATGGAATGACCGTTTCTCAGATATCTATGCTTTATGTGTGGCCTATCCTG
AACCCCTTGGAGAAAGACTTTATACAGAAACTAAGATTTTTTTGGAAAATCATGTTCGGCATTTGCATAAGAGAGTTTTGGAGTCAGAAG
AACAAGTACTTGTTATGTATCATAGGTACTGGGAAGAATACAGCAAGGGTGCAGACTATATGGACTGCTTATATAGGTATCTCAACACCC
AGTTTATTAAAAAGAATAAATTAACAGAAGCGGACCTTCAGTATGGCTATGGTGGTGTAGATATGAATGAACCACTTATGGAAATAGGAG
AGCTAGCATTGGATATGTGGAGGAAATTGATGGTTGAACCACTTCAGGCCATCCTTATCCGAATGCTGCTCCGAGAAATCAAAAATGATC
GTGGTGGAGAAGACCCAAACCAGAAAGTAATCCATGGGGTTATTAACTCCTTTGTTCATGTTGAACAGTATAAGAAAAAATTCCCCTTAA
AGTTTTATCAGGAAATTTTTGAGTCTCCCTTTCTGACTGAAACAGGAGAGTATTACAAACAAGAAGCTTCAAATTTATTACAAGAATCAA
ACTGCTCACAGTATATGGAAAAGCTGGTAGCAGTGTTTGATGAGCAGGATCCACATCACGGAGGTGATGGCACCAGTGCCAGTTCCACGG
GTACCCAGAGCCCAGAGATATTTGGTAGTGAGCTTGGCACCAACAATGTCTCAGCCTTTCAGCCTTACCAAGCAACAAGTGAAATTGAGG
TCACACCTTCAGTCCTTCGAGCAAATATGCCTCTTCATGTTCGACGCAGTAGTGACCCAGCTCTAATTGGCCTCTCCACTTCTGTCAGTG
ATAGTAATTTTTCCTCTGAAGAGCCTTCAAGGAAAAATCCCACACGCTGGTCAACAACAGCTGGCTTCCTCAAGCAGAACACTGCTGGGA
GTCCTAAAACCTGCGACAGGAAGAAAGATGAAAACTACAGAAGCCTCCCGCGGGATACTAGTAACTGGTCTAACCAATTTCAGAGAGACA
ATGCTCGCTCGTCTCTGAGTGCCAGTCACCCAATGGTGGGCAAGTGGCTGGAGAAACAAGAACAGGATGAGGATGGGACAGAAGAGGATA
ACAGTCGTGTTGAACCTGTTGGACATGCTGACACGGGTTTGGAGCATATACCCAACTTTTCTCTGGATGATATGGTAAAGCTCGTAGAAG
TCCCCAACGATGGAGGGCCTCTGGGAATCCACGTAGTGCCTTTCAGTGCTCGAGGCGGCAGAACCCTGGGGTTATTAGTAAAACGATTGG
AGAAAGGTGGTAAAGCTGAACATGAAAATCTTTTTCGTGAGAATGATTGCATTGTCAGGATTAATGATGGCGACCTTCGAAATAGAAGAT
TTGAACAAGCACAACATATGTTTCGCCAAGCCATGCGTACACCCATCATTTGGTTCCATGTGGTTCCTGCAGCAAATAAAGAGCAGTATG
AACAACTATCCCAAAGTGAGAAGAACAATTACTATTCAAGCCGTTTTAGCCCTGACAGCCAGTATATTGACAACAGGAGTGTGAACAGTG
CAGGGCTTCACACGGTGCAGAGAGCACCCCGACTGAACCACCCGCCTGAGCAGATAGACTCTCACTCAAGACTACCTCATAGCGCACACC
CCTCGGGAAAACCACCATCCGCTCCAGCCTCGGCACCTCAGAATGTATTTAGTACGACTGTAAGCAGTGGTTATAACACCAAAAAAATAG
GCAAGAGGCTTAATATCCAGCTTAAGAAAGGTACAGAAGGTTTGGGATTCAGCATCACTTCCAGAGATGTAACAATAGGTGGCTCAGCTC
CAATCTATGTGAAAAACATTCTCCCCCGGGGGGCGGCCATTCAGGATGGCCGACTTAAGGCAGGAGACAGACTTATAGAGGTAAATGGAG
TAGATTTAGTGGGCAAATCCCAAGAGGAAGTTGTTTCGCTGTTGAGAAGCACCAAGATGGAAGGAACTGTGAGCCTTCTGGTCTTTCGCC
AGGAAGACGCCTTCCACCCAAGGGAACTGAAAGCAGAAGATGAGGATATTGTTCTTACACCTGATGGCACCAGGGAATTTCTGACATTTG
AAGTCCCACTTAATGATTCAGGATCTGCAGGCCTTGGTGTCAGTGTCAAAGGTAACCGGTCAAAAGAGAACCACGCAGATTTGGGAATCT
TTGTCAAGTCCATTATTAATGGAGGAGCAGCATCTAAAGATGGAAGGCTTCGGGTGAATGATCAACTGATAGCAGTAAATGGAGAATCCC
TGTTGGGCAAGACAAACCAAGATGCCATGGAAACCCTAAGAAGGTCTATGTCTACTGAAGGCAATAAACGAGGAATGATCCAGCTTATTG
TTGCAAGGAGAATAAGCAAGTGCAATGAGCTGAAGTCACCTGGGAGCCCCCCTGGACCTGAGCTGCCCATTGAAACAGCGTTGGATGATA
GAGAACGAAGAATTTCCCATTCCCTCTACAGTGGGATTGAGGGGCTTGATGAATCGCCCAGCAGAAATGCTGCCCTCAGTAGGATAATGG
GTAAATACCAGCTGTCCCCTACAGTGAATATGCCCCAAGATGACACTGTCATTATAGAAGATGACAGGTTGCCAGTGCTTCCTCCACATC
TCTCTGACCAGTCCTCTTCCAGCTCCCATGATGATGTGGGGTTTGTGACGGCAGATGCTGGTACTTGGGCCAAGGCTGCAATCAGTGATT
CAGCCGACTGCTCTTTGAGTCCAGATGTTGATCCAGTTCTTGCTTTTCAACGAGAAGGATTTGGACGTCAGAGTATGTCAGAAAAACGCA
CAAAGCAATTTTCAGATGCCAGTCAATTGGATTTCGTTAAAACACGAAAATCAAAAAGCATGGATTTAGGTATAGCTGACGAGACTAAAC
TCAATACAGTGGATGACCAGAAAGCAGGTTCTCCCAGCAGAGATGTGGGTCCTTCCCTGGGTCTGAAGAAGTCAAGCTCGTTGGAGAGTC
TGCAGACCGCAGTTGCCGAGGTGACTTTGAATGGGGATATTCCTTTCCATCGTCCACGGCCGCGGATAATCAGAGGCAGGGGATGCAATG
AGAGCTTCAGAGCTGCCATCGACAAATCTTATGATAAACCCGCGGTAGATGATGATGATGAAGGCATGGAGACCTTGGAAGAAGACACAG
AAGAAAGTTCAAGATCAGGGAGAGAGTCTGTATCCACAGCCAGTGATCAGCCTTCCCACTCTCTGGAGAGACAAATGAATGGAAACCAAG
AGAAAGGTGATAAGACTGATAGAAAAAAGGATAAAACTGGAAAAGAAAAGAAGAAAGATAGAGATAAGGAGAAGGATAAAATGAAAGCCA
AGAAGGGAATGCTGAAGGGCTTGGGAGACATGTTCAGGTTTGGCAAACATCGAAAAGATGACAAGATTGAGAAAACGGGTAAAATAAAAA
TACAGGAATCCTTTACATCAGAAGAGGAGAGGATACGAATGAAGCAGGAGCAGGAGAGGATTCAAGCCAAAACTCGAGAATTTAGGGAAC
GACAAGCTCGAGAGCGTGACTATGCTGAAATTCAAGATTTTCATCGGACATTTGGCTGTGATGATGAGTTAATGTATGGGGGAGTTTCTT
CTTATGAAGGTTCCATGGCTCTCAACGCTAGACCTCAGAGCCCACGAGAAGGGCATATGATGGATGCTTTGTATGCCCAAGTCAAGAAGC
CGCGGAATTCCAAACCCTCACCTGTAGACAGTAACAGATCAACTCCTAGCAATCATGATCGGATACAGCGTCTGAGGCAAGAATTTCAGC
AAGCAAAGCAAGATGAAGATGTAGAAGATCGTCGGCGGACCTATAGTTTTGAGCAACCCTGGCCGAACGCACGGCCGGCGACGCAGAGCG
GGCGACACTCGGTGTCCGTGGAGGTGCAGATGCAGCGGCAGCGGCAGGAGGAGCGCGAGAGCTCCCAGCAGGCCCAGCGCCAGTACAGCT
CTCTGCCTCGGCAAAGCAGGAAAAATGCCAGCTCGGTCTCCCAGGACTCTTGGGAGCAGAACTACTCCCCTGGGGAAGGCTTCCAGAGTG
CCAAAGAGAACCCCAGGTACTCCAGCTACCAAGGCTCCAGGAACGGCTACCTGGGAGGACATGGCTTCAACGCCAGGGTCATGCTGGAAA
CTCAGGAGCTCCTTCGCCAGGAACAGAGGCGGAAGGAGCAGCAGATGAAGAAGCAGCCTCCTTCCGAGGGGCCCAGCAACTATGACTCGT
ATAAGAAAGTCCAGGACCCCAGTTACGCCCCTCCCAAGGGGCCCTTCCGGCAAGATGTGCCCCCCTCCCCTTCTCAGGTTGCGAGGCTGA
ACAGACTTCAGACTCCTGAGAAAGGGAGGCCCTTCTATTCCTGAGCACGCAAATAACGGATGCTTCATGTCGCGCAATAAAAGACATTTT
CCTATGAAGACTTGTATTTTGGGAGTTTTTTTAAAACCTCGATGGTACTATGGAGTATTTCTGTTGTTGGTATCAGTGCCTTTAAGCGGT
GTAGGCAAAGAAATGGAAGGCCTTAATGTCTTTGCCACTATGTCTCAAGTGTCTGTTTCATGGAAGGATTTCCCACCCTGTGACAATCAT
CTGTTTGAGGTGTTCATATGCTCTGCGCCTCTCCACAGTACCAGGAATCTCGGCCCTACTCATGAGTTGTCCGCGGCTTGGTTGTAACAT
CCCTGCACCACTTGCAGTGACAAATTCACCTGAAGTGGAGGATGACGTGCGGCCCTGTTTCTCCCTCTAAGTTCTCTTAGCTATGGGATG
ACATCTTAGTCTCTGGTGGAGGAAAAGTGGGCGACATACACCAAAAATTGGGGCTTTCTGGTACTTCACAGCACAGCCATTTGTCGTACT
TTGTCATCACTGTGGTTTTCTCTTTCCTTTCTCAGCTCTTTGTGACGGGAGAGTCGGTCATCCTATTACAGAAGCTAAGCCATAGTCCAA
CATTGTTTGGTCACCATGGGGGTCCTTTTGTAACTGCCTTATGACTCAACATTACCAATAAAGTGATGATCCTGGTCTGCGTTTATACAT
ACGCTTGTTCGGTCCTGTTCCTGACACGTGGGTTGAGTCACCACAGCTCTGTGTGGGGAACGTGGGAGACAGGAGTGGCTCCTGCCGGGG
GAAGCTGGGCCTGCCATTGGCCCTGTGTCTATCATGAGGGGAGAGCTAAGAAAGAAATTCTCCTAGGAAGAGCTCATGGCCCAGTACATC
CTAGTAATTATTTTAATTAGTTTTTGTTCTGACAGCTTGTCAGGAAGGGCACAGAATGGGACAGAGATAAACCAGACAGTCATTTTGATC
TGCTCTCTACGGTTTTTCAAGTCAGAGGCAATTGATGCTTGTCTAATGCATCCACACACTGCATGTCTGACTGGCGATGCCGCGCTCCTA
AGTAGTTCTGCCATGAAACATAAAAGACAAAGGAAAAGCCGTTACACATCACACAGAGAACATTTTCGGGTCCCACAGCGGTGGTGGCAG
GAAGCTCACTCTCGCGTCAGTATTAGAGTGTGTGTGTGGGTCTCGGGGATCTCGGTGGCTCCCATCTTCCTTCATTGTTCTGAACATCCT
GTATTGTAAACCATGGCTGGGGTGCTAAAGTGCCTGTGAATCCCGATGTGGAAAAAGCTGGAGGTGAAAGCTCAGCATACCATGTATTTA
CTTTAAAAACAGAAAAAAAGACATGTATGGATATGTCTATTTTTTTTTTATTGGCACATTGTATTTTTGTGTTGACTTGTTTTTAGAAAT
GATGTGTCCACACACGTACCCGTGTCTCTTCTGCATTTCTGTGTCATGGTTCTGTTTCTTAATCACGTGCGGCGGTGTCTAAGTGGTGTT
ACCAGTGTACGCGCAGTGACCTTGGATGACAGTGGCTCTTTCTCACAGCCTCCCCTGAGCTGTGAGAAACAGCTTTCTCTGTACATATGC

>20659_20659_16_CUL2-PARD3_CUL2_chr10_35333494_ENST00000537177_PARD3_chr10_34806087_ENST00000545693_length(amino acids)=1537AA_BP=1
MNAVCRRKQQTLYFMYRVTWSTFWLRFQHYTCTMSLKPRVVDFDETWNKLLTTIKAVVMLEYVERATWNDRFSDIYALCVAYPEPLGERL
YTETKIFLENHVRHLHKRVLESEEQVLVMYHRYWEEYSKGADYMDCLYRYLNTQFIKKNKLTEADLQYGYGGVDMNEPLMEIGELALDMW
RKLMVEPLQAILIRMLLREIKNDRGGEDPNQKVIHGVINSFVHVEQYKKKFPLKFYQEIFESPFLTETGEYYKQEASNLLQESNCSQYME
KLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSE
EPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASHPMVGKWLEKQEQDEDGTEEDNSRVEPV
GHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHM
FRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPS
APASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKS
QEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIIN
GGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISH
SLYSGIEGLDESPSRNAALSRIMGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLS
PDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLGIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAE
VTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTD
RKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERD
YAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDED
VEDRRRTYSFEQPWPNARPATQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSPGEGFQSAKENPRY
SSYQGSRNGYLGGHGFNARVMLETQELLRQEQRRKEQQMKKQPPSEGPSNYDSYKKVQDPSYAPPKGPFRQDVPPSPSQVARLNRLQTPE

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for CUL2-PARD3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgenePARD3chr10:35333494chr10:34806087ENST00000340077121935_135674.01032.0FRMD4A
TgenePARD3chr10:35333494chr10:34806087ENST00000346874124935_135674.01320.0FRMD4A
TgenePARD3chr10:35333494chr10:34806087ENST00000350537124935_135674.01311.0FRMD4A
TgenePARD3chr10:35333494chr10:34806087ENST00000374776120935_135674.0989.0FRMD4A
TgenePARD3chr10:35333494chr10:34806087ENST00000374788125935_135674.01354.0FRMD4A
TgenePARD3chr10:35333494chr10:34806087ENST00000374789125935_135674.01357.0FRMD4A
TgenePARD3chr10:35333494chr10:34806087ENST00000374794121935_135674.01245.0FRMD4A
TgenePARD3chr10:35333494chr10:34806087ENST00000545260123935_135674.01267.0FRMD4A
TgenePARD3chr10:35333494chr10:34806087ENST00000545693124935_135674.01341.0FRMD4A
TgenePARD3chr10:35333494chr10:34806087ENST00000340077121712_93674.01032.0PRKCI and PRKCZ
TgenePARD3chr10:35333494chr10:34806087ENST00000346874124712_93674.01320.0PRKCI and PRKCZ
TgenePARD3chr10:35333494chr10:34806087ENST00000350537124712_93674.01311.0PRKCI and PRKCZ
TgenePARD3chr10:35333494chr10:34806087ENST00000374776120712_93674.0989.0PRKCI and PRKCZ
TgenePARD3chr10:35333494chr10:34806087ENST00000374788125712_93674.01354.0PRKCI and PRKCZ
TgenePARD3chr10:35333494chr10:34806087ENST00000374789125712_93674.01357.0PRKCI and PRKCZ
TgenePARD3chr10:35333494chr10:34806087ENST00000374794121712_93674.01245.0PRKCI and PRKCZ
TgenePARD3chr10:35333494chr10:34806087ENST00000545260123712_93674.01267.0PRKCI and PRKCZ
TgenePARD3chr10:35333494chr10:34806087ENST00000545693124712_93674.01341.0PRKCI and PRKCZ


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for CUL2-PARD3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for CUL2-PARD3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource