FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:CXADR-FAM184B (FusionGDB2 ID:20802)

Fusion Gene Summary for CXADR-FAM184B

check button Fusion gene summary
Fusion gene informationFusion gene name: CXADR-FAM184B
Fusion gene ID: 20802
HgeneTgene
Gene symbol

CXADR

FAM184B

Gene ID

1525

27146

Gene nameCXADR Ig-like cell adhesion moleculefamily with sequence similarity 184 member B
SynonymsCAR|CAR4/6|HCAR-
Cytomap

21q21.1

4p15.32-p15.31

Type of geneprotein-codingprotein-coding
Descriptioncoxsackievirus and adenovirus receptor46 kD coxsackievirus and adenovirus receptor (CAR) proteinCVB3-binding proteinHCVADRcoxsackie virus and adenovirus receptorcoxsackievirus B-adenovirus receptorprotein FAM184B
Modification date2020031320200313
UniProtAcc

P78310

Q9ULE4

Ensembl transtripts involved in fusion geneENST00000284878, ENST00000306618, 
ENST00000400165, ENST00000400166, 
ENST00000400169, ENST00000356275, 
ENST00000265018, 
Fusion gene scores* DoF score13 X 11 X 6=8582 X 2 X 2=8
# samples 132
** MAII scorelog2(13/858*10)=-2.72246602447109
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(2/8*10)=1.32192809488736
Context

PubMed: CXADR [Title/Abstract] AND FAM184B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCXADR(18937929)-FAM184B(17666282), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCXADR

GO:0007157

heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

12869515|15800062

HgeneCXADR

GO:0031532

actin cytoskeleton reorganization

17675666


check buttonFusion gene breakpoints across CXADR (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FAM184B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-21-1081-01ACXADRchr21

18937929

+FAM184Bchr4

17666282

-


Top

Fusion Gene ORF analysis for CXADR-FAM184B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000284878ENST00000265018CXADRchr21

18937929

+FAM184Bchr4

17666282

-
In-frameENST00000306618ENST00000265018CXADRchr21

18937929

+FAM184Bchr4

17666282

-
In-frameENST00000400165ENST00000265018CXADRchr21

18937929

+FAM184Bchr4

17666282

-
In-frameENST00000400166ENST00000265018CXADRchr21

18937929

+FAM184Bchr4

17666282

-
In-frameENST00000400169ENST00000265018CXADRchr21

18937929

+FAM184Bchr4

17666282

-
intron-3CDSENST00000356275ENST00000265018CXADRchr21

18937929

+FAM184Bchr4

17666282

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000400166CXADRchr2118937929+ENST00000265018FAM184Bchr417666282-57098968902482530
ENST00000400165CXADRchr2118937929+ENST00000265018FAM184Bchr417666282-54166036122189525
ENST00000306618CXADRchr2118937929+ENST00000265018FAM184Bchr417666282-56047918002377525
ENST00000400169CXADRchr2118937929+ENST00000265018FAM184Bchr417666282-5830101702603867

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000400166ENST00000265018CXADRchr2118937929+FAM184Bchr417666282-0.0012588220.9987412
ENST00000400165ENST00000265018CXADRchr2118937929+FAM184Bchr417666282-0.0016229810.99837697
ENST00000306618ENST00000265018CXADRchr2118937929+FAM184Bchr417666282-0.0014395760.9985605
ENST00000400169ENST00000265018CXADRchr2118937929+FAM184Bchr417666282-0.0002169370.9997831

Top

Fusion Genomic Features for CXADR-FAM184B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for CXADR-FAM184B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr21:18937929/chr4:17666282)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CXADR

P78310

FAM184B

Q9ULE4

FUNCTION: Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. {ECO:0000269|PubMed:11734628, ECO:0000269|PubMed:12297051, ECO:0000269|PubMed:15800062, ECO:0000269|PubMed:19064666, ECO:0000269|PubMed:9096397}.; FUNCTION: (Microbial infection) Acts as a receptor for adenovirus type C. {ECO:0000269|PubMed:10567268, ECO:0000269|PubMed:10666333, ECO:0000269|PubMed:12297051, ECO:0000269|PubMed:9733828}.; FUNCTION: (Microbial infection) Acts as a receptor for Coxsackievirus B1 to B6. {ECO:0000269|PubMed:10814575, ECO:0000269|PubMed:14978041}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCXADRchr21:18937929chr4:17666282ENST00000400165+44141_228201201.0DomainNote=Ig-like C2-type 2
HgeneCXADRchr21:18937929chr4:17666282ENST00000400165+4420_134201201.0DomainNote=Ig-like C2-type 1
HgeneCXADRchr21:18937929chr4:17666282ENST00000400169+78141_228339353.0DomainNote=Ig-like C2-type 2
HgeneCXADRchr21:18937929chr4:17666282ENST00000400169+7820_134339353.0DomainNote=Ig-like C2-type 1
HgeneCXADRchr21:18937929chr4:17666282ENST00000400165+44360_365201201.0MotifNote=PDZ-binding
HgeneCXADRchr21:18937929chr4:17666282ENST00000400165+4420_237201201.0Topological domainExtracellular
HgeneCXADRchr21:18937929chr4:17666282ENST00000400165+44259_365201201.0Topological domainCytoplasmic
HgeneCXADRchr21:18937929chr4:17666282ENST00000400169+7820_237339353.0Topological domainExtracellular
HgeneCXADRchr21:18937929chr4:17666282ENST00000400165+44238_258201201.0TransmembraneHelical
HgeneCXADRchr21:18937929chr4:17666282ENST00000400169+78238_258339353.0TransmembraneHelical
TgeneFAM184Bchr21:18937929chr4:17666282ENST00000265018618584_7695321061.0Coiled coilOntology_term=ECO:0000255
TgeneFAM184Bchr21:18937929chr4:17666282ENST00000265018618806_9345321061.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCXADRchr21:18937929chr4:17666282ENST00000284878+17141_2280366.0DomainNote=Ig-like C2-type 2
HgeneCXADRchr21:18937929chr4:17666282ENST00000284878+1720_1340366.0DomainNote=Ig-like C2-type 1
HgeneCXADRchr21:18937929chr4:17666282ENST00000306618+16141_2280325.0DomainNote=Ig-like C2-type 2
HgeneCXADRchr21:18937929chr4:17666282ENST00000306618+1620_1340325.0DomainNote=Ig-like C2-type 1
HgeneCXADRchr21:18937929chr4:17666282ENST00000356275+13141_228090.0DomainNote=Ig-like C2-type 2
HgeneCXADRchr21:18937929chr4:17666282ENST00000356275+1320_134090.0DomainNote=Ig-like C2-type 1
HgeneCXADRchr21:18937929chr4:17666282ENST00000400166+15141_2280253.0DomainNote=Ig-like C2-type 2
HgeneCXADRchr21:18937929chr4:17666282ENST00000400166+1520_1340253.0DomainNote=Ig-like C2-type 1
HgeneCXADRchr21:18937929chr4:17666282ENST00000284878+17360_3650366.0MotifNote=PDZ-binding
HgeneCXADRchr21:18937929chr4:17666282ENST00000306618+16360_3650325.0MotifNote=PDZ-binding
HgeneCXADRchr21:18937929chr4:17666282ENST00000356275+13360_365090.0MotifNote=PDZ-binding
HgeneCXADRchr21:18937929chr4:17666282ENST00000400166+15360_3650253.0MotifNote=PDZ-binding
HgeneCXADRchr21:18937929chr4:17666282ENST00000400169+78360_365339353.0MotifNote=PDZ-binding
HgeneCXADRchr21:18937929chr4:17666282ENST00000284878+1720_2370366.0Topological domainExtracellular
HgeneCXADRchr21:18937929chr4:17666282ENST00000284878+17259_3650366.0Topological domainCytoplasmic
HgeneCXADRchr21:18937929chr4:17666282ENST00000306618+1620_2370325.0Topological domainExtracellular
HgeneCXADRchr21:18937929chr4:17666282ENST00000306618+16259_3650325.0Topological domainCytoplasmic
HgeneCXADRchr21:18937929chr4:17666282ENST00000356275+1320_237090.0Topological domainExtracellular
HgeneCXADRchr21:18937929chr4:17666282ENST00000356275+13259_365090.0Topological domainCytoplasmic
HgeneCXADRchr21:18937929chr4:17666282ENST00000400166+1520_2370253.0Topological domainExtracellular
HgeneCXADRchr21:18937929chr4:17666282ENST00000400166+15259_3650253.0Topological domainCytoplasmic
HgeneCXADRchr21:18937929chr4:17666282ENST00000400169+78259_365339353.0Topological domainCytoplasmic
HgeneCXADRchr21:18937929chr4:17666282ENST00000284878+17238_2580366.0TransmembraneHelical
HgeneCXADRchr21:18937929chr4:17666282ENST00000306618+16238_2580325.0TransmembraneHelical
HgeneCXADRchr21:18937929chr4:17666282ENST00000356275+13238_258090.0TransmembraneHelical
HgeneCXADRchr21:18937929chr4:17666282ENST00000400166+15238_2580253.0TransmembraneHelical
TgeneFAM184Bchr21:18937929chr4:17666282ENST00000265018618192_3335321061.0Coiled coilOntology_term=ECO:0000255
TgeneFAM184Bchr21:18937929chr4:17666282ENST00000265018618402_5025321061.0Coiled coilOntology_term=ECO:0000255
TgeneFAM184Bchr21:18937929chr4:17666282ENST0000026501861851_1595321061.0Coiled coilOntology_term=ECO:0000255


Top

Fusion Gene Sequence for CXADR-FAM184B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>20802_20802_1_CXADR-FAM184B_CXADR_chr21_18937929_ENST00000306618_FAM184B_chr4_17666282_ENST00000265018_length(transcript)=5604nt_BP=791nt
ATGGCGCTCCTGCTGTGCTTCGTGCTCCTGTGCGGAGTAGTGGATTTCGCCAGAAGTTTGAGTATCACTACTCCTGAAGAGATGATTGAA
AAAGCCAAAGGGGAAACTGCCTATCTGCCATGCAAATTTACGCTTAGTCCCGAAGACCAGGGACCGCTGGACATCGAGTGGCTGATATCA
CCAGCTGATAATCAGAAGGTGGATCAAGTGATTATTTTATATTCTGGAGACAAAATTTATGATGACTACTATCCAGATCTGAAAGGCCGA
GTACATTTTACGAGTAATGATCTCAAATCTGGTGATGCATCAATAAATGTAACGAATTTACAACTGTCAGATATTGGCACATATCAGTGC
AAAGTGAAAAAAGCTCCTGGTGTTGCAAATAAGAAGATTCATCTGGTAGTTCTTGTTAAGCCTTCAGGTGCGAGATGTTACGTTGATGGA
TCTGAAGAAATTGGAAGTGACTTTAAGATAAAATGTGAACCAAAAGAAGGTTCACTTCCATTACAGTATGAGTGGCAAAAATTGTCTGAC
TCACAGAAAATGCCCACTTCATGGTTAGCAGCTTCAAATAAAGCTGGACTAATTGCAGGAGCCATTATAGGAACTTTGCTTGCTCTAGCG
CTCATTGGTCTTATCATCTTTTGCTGTCGTAAAAAGCGCAGAGAAGAAAAATATGAAAAGGAAGTTCATCACGATATCAGGTAGCTGCCC
CTAATCTAAGTCGAATGGGTGCGATTCCTGTGATGATTCCAGCACAGAGCAAGGATGGGTCTATAGTATAGGATCCATGCTTGAAGCTGG
ATGAAACTTCGCCGAGAGGAGAGGAGTATCAAGATAAGTTAGCAGCTGAAGAAGGAACCAGCAGTGATGAAGAAGAAAGGACCAAAGTGC
TTCTCAAGGAGGGAAGTGACCCACAACCTCCACTGGGCTCTTTGTTGAAGGAGAAAACATCCAAAATCCAGCGTCTAGAGGAGGACTGGC
AAAGCCAGAAGGCCAAATTGCAAGCCCAGGTCTCACAGATGCAGCAGGCTCTGGAGCAGTGCACCAGCAACTACAGGGAGGACCTGCAGG
CACTCAAGCAGCTCTCGGACCTGGAGAGGGAGAAGCTGCAGCGTGAGCTCCAGGAGACCACTCAGCAGAACCACGCCATGAAAGCCCAGC
TCGAGGCTTCCCACCAGAGAGCCCTGCGCATGCTGGAGAAGGCCAGACATCAGGAACTCAAGGCCACAGAGGAACGCTTGAAGAAGGAAT
CCAGCCACAGCCTCCAGATCCAACACCAGACACACCGACTGGAGCTCCAGGCCTTGGAGGAAAAGGCCAGGCAAGAGCTGCAGGAGGAGC
GTGAGAGGATGCAGGCACAGCAGGCCCTGCTGCTAGAGTCGCTCAGACAGGAGCTGTCGGAGCAGCAAGCTGCCTGTTCTGGGCACCAGA
AGGACTTGGAGGCACTGCAGGCCGAGCTGAGGGCTCTGGGCAGACAGCAAGCCAGCAGCCAGTGTCCAGGAGACAGCAAGGATCACATAA
TCGCCACAGAGGAGCGGGGCGGCCCGGGCCAGGCCGGCTCCCCACCGGGCGCTGCTGGGCAGGGTTCCGGCGAGGGATGCGGGCTCTGGG
AGGAGAACGCGCAGCTCCAGGACGCGGTGCGGCGGCTGCGCGCGGAGGTGGAGCAGCATCAGCAGGAGGCGCAGAAGCTCCGAGACCAGC
GCAGGTTCCTGGAGGAGACTCAGCAAGCCCAGCGGGCCAGGGAGGTGGAGACACTGCGCCAGGAACACCGGAAGGAGATGCAGGCCATGG
TGGCAGATTTCAGTAGTGCCCAGGCCCAGCTCCAGGCCCGGCTGGCTGCCCTGGAAGCCGAACTGAAAGATTCCGGAGAGAAGCCAGGGA
AGGGAGCGTCCAGGCCCGAGGACCTTCAGCTCATTGGCCGCCTGCAGACCCGCCTGAAGGAGAGAGAGGACATCATCAAGCAGCTCACGG
AAGAGAGAAGATTTCACTACGCAGCATTCCCCAGTGCCATGTCCCACCGGAATCGGTCTTTCTCTTTCAATCCTCACCCGGGATATTTGA
CCCCTTCCATGAAGAAAAAGAAGGTGGAGGACGTGCCCAGCCGCGTGGTCAGCGTGCCGAACCTCGCCTCCTATGCAAAGAACTTTCTGA
GTGGCGATCTGAGTTCCAGGATTAATGCCCCTCCAATAACTACATCACCCAGCTTGGACCCAAGCCCCAGCTGTGGCCGGACCTACAAAC
CCAACCAGTCTACAGATGCAAAAACTGCCACAAGGACCCCAGATGGTGAAACGGCCCAAGCCAAAGAAGTCCAGCAGAAACAGGGCTCTC
CGCACCAGGAATGGTTCACCAAGTACTTTTCTTTCTAAGCTAACCTTTGGGATACATCACAGAGGATACTTGAAAAACATTTATTTTAAA
TCATCCGATTGAAGGAATGAACTAACACCAACCAACCAAATAATATGCTTATGATTTATATATGATAGCTAAAACAAATTTTGGCGTTAA
CACTTCATACTGTTCTGCCAGGCACAGCAGCTCACGCCTGTAATCCCATCACTTTGGGAGGCTGAGGCAGATGGACTGCTTGAGTCCAGG
AATTTGAGACCAGCCTGGCCAATATGGTGAAACCCCATCTCTACAAAATATACAAAAATTAGCCAGGCATGGTGGCGTGTGCCTGTGGTC
CCAGGTACTTGGGGGACTGAGGCGGGAGGATCACTTGAACCTAGGAGGCAGAGGTTGCAGTGAGCCAAGTTCGAACTCCTGCATTCCAAC
CAGCCTGGGTGACAGAGGGAGACCCTGTCTCCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATTGACATTAAACCA
GTGTTATTAAAAGTCATCTATAGGAAAATGTTATTAGCGTTACTAATGACCCATACCTTGTATTTCTAGTGTCCATAACATCATACTCCA
TTTTGTGGAACATCAGACTTTGTGATTTCCATGATCTATTTCAAAAGTGGTTGTACTTGTCCTTAGGATGCTAGTCAACTCCACTGGAAA
GCTGTTTCTATGTAAAATGATGCAATTCCAAAATGCACATCTAACCTCAATAGGAAGACAAATAACAGTTAAACAGGAAAGCCAACTAAA
AACAAACCAAACCTACCAGAAATGGATGGTAGCATGCTTGGACTGAATACTTTCACTTCCTTGGTCTAAGACAAGCAGCAGATTATAGAT
GGGATAACACCCACCTCTAAAAGGGCTTTGCAAGGATTAAGCAAGATAACATAAATTAACATGAATTGGAATTAAGTACCACAAGGTTTT
TCTGTAAATAACCAATCCTAGCCCAGTTATAGGTCTCAGTGTAATGACCATAGTGCCAACATGATCACTTGTGAAGGTCTCTAGATTATC
TGTTCTTTGAAGTCAAAGATCTTCTAGACTGGGCACATGGCTCATGCCTGTAATCCCAACACTTTGGGAGGCTGAGATGGGAGGAGAGCT
TGAGGCCAGGAATTTGAGACCAGCCTGGGCAACACAGCGAGACCTCCATCTCTACAAAAAAATAATTAGCCCAAAGAAAACCCAGCTACT
TGGAAGTCTGAGGTAGGACAGCATGAGCCCAAGAGTTCGAGACCAGCCTGGGCAAGATAGTGAGATCCCATCTCTACAGATTAAAAAAAT
ATATATATATATCCCCTGAACCTCTGGTCTTTGGGTTTGAGCCATTTGCCTCATGGTGTGTTGCTTCTTCACTGCATGAATTCCCAGTGG
GTTAAAGGAACCGCAATGGCTGTTCACGGTGCTGACCTTGCTCTCAGTCCACACTGATTTGTCTTACCTTCTGACAGAGCAATGTGATTT
GACAAGACTCAATAACAACTTTTAGGGGGCAAAATATTTTTTCAGTCTTTGGTGCTGGCCCAGAAGGTGGCCCACAAACCAATGTTAATT
CTATGCATTGTCAAATCTTTGCTCTTTGAATAAAACTTTGAATAACTGGGCAATAAAAATGGTTGACTTGTATTGATTTTCCACAGAAAG
GTAAAATTAGATGAAGACAGCTTAGAAATAGAAAGTTCAGTTCACATTAACCTCAATCACACCATCTTAAAAAAAAAAAAGCTGATTACA
TATAACTGTCAAACTTACGTATTAAAGGTAAATTTACTGCCTAATCAAAACGAGGCTCCAATGCATTTTTAAATGCAAACAAACACTTGT
CACCATACATTAACACACCATACTGTTTTTCACTACCAAATATTTTTTGTGAGTTTCCCGCTTAGAGTGTCTTAGTTCGTTCAGGCTGCT
CTAACAAAATATCTTACTTATACTGGATAATTTATAAACAATAGAAATATGTCACTCACAGTCCTAGAGGCTAAGTCCAAGATCAAGGCA
CCAGCAGATATGGAGTCTGGGGAGGGCCCATTCTTCAGAAATGGGTGCCTGCTACGTGTCCTTACATGGTGGAAGAGGCAAGAGCGCCTC
CCTGAGCCTCTTTTGTAAGGGTACTTATCCTACTCATGAGGGTGAAGCCCTCATGACTCCATTGCTTCCCAAAAGCCCCACCTCTTAATA
CTATTACATTGACATTAGGTTCCAACATATGAATTTTGGAAGGGACATCAACATTCAGGACATAGCAGTGAACCCTGTAGGACTGCTCTT
TATTTTGTGCTTTCAAAAAGACTACATACAGGTGGTTCTATTTTTGTGTGTTGAAACACTTTCCCAGGCTGCACTTTGCATTTCTGTCCT
TAAACTCAGCATGATCCCTGGGCAAGGAGAAAATTTTACTAGTTGAGATCGTACATAGGTTTTGACTCCTTTCTTGCTGCAGGTGACTGA
AAAGATCTTTCAGTCTTAAATTTCTAAATTCTACCCTGCAATGATTATATCTTTGTTAACAAAATCTTTGCATGCTTCCATAATTTTTTA
TTGAGGCCATATGCCTTGGGTATTGAAGTAAGGCATTTAAGGACACAAACTTAAGCTTTTTGTTTGTTATTACCAAACTGCCATTCAGAA
AGTTTCTAACAATTTACACCCTTACCAGCAGTAAATGAACCTACTGTGCCCTAACACTATTGACAAAGAAATACAATTTGATAGATAAAA
CATTCTATTTTAGTTTGCATAATGATTCCATCAATCTCTCAACAGCAGAGCGGTCTAGAGATGACAGTGATGGCGTAGAGGTGACAGTGA
AGATGAAGAGAAATTATCCAATTCGGGATTAAGTTAAGAGAGAGAAAAAAACAGTATTTAATGGTAAATCTCTTCAGGCTGTATTATGAC
AGGGGTGGAAGAGTTAATATGTTCCTGCAGCAAAACTGAAAGGAATACTATCTGTTCCACATGAAAGCAAACTGTTTTGTAATTGGGGTA
GGTAAAAATGGATTCACCCAGTCAATGGCTGCACACCACATACCTGAGCCCTTAACTGCTCTAACACTGATGTAATATCCAACCCAACAT
TTGTGATTGAGGCTACTTGGTTAATTTTTCTCCAGGATCCATCTGGATTCTGCAGATGAGGCTGGCAAATTAAATGGAACTATGATAGGG

>20802_20802_1_CXADR-FAM184B_CXADR_chr21_18937929_ENST00000306618_FAM184B_chr4_17666282_ENST00000265018_length(amino acids)=525AA_BP=
MKLDETSPRGEEYQDKLAAEEGTSSDEEERTKVLLKEGSDPQPPLGSLLKEKTSKIQRLEEDWQSQKAKLQAQVSQMQQALEQCTSNYRE
DLQALKQLSDLEREKLQRELQETTQQNHAMKAQLEASHQRALRMLEKARHQELKATEERLKKESSHSLQIQHQTHRLELQALEEKARQEL
QEERERMQAQQALLLESLRQELSEQQAACSGHQKDLEALQAELRALGRQQASSQCPGDSKDHIIATEERGGPGQAGSPPGAAGQGSGEGC
GLWEENAQLQDAVRRLRAEVEQHQQEAQKLRDQRRFLEETQQAQRAREVETLRQEHRKEMQAMVADFSSAQAQLQARLAALEAELKDSGE
KPGKGASRPEDLQLIGRLQTRLKEREDIIKQLTEERRFHYAAFPSAMSHRNRSFSFNPHPGYLTPSMKKKKVEDVPSRVVSVPNLASYAK

--------------------------------------------------------------
>20802_20802_2_CXADR-FAM184B_CXADR_chr21_18937929_ENST00000400165_FAM184B_chr4_17666282_ENST00000265018_length(transcript)=5416nt_BP=603nt
ATGGCGCTCCTGCTGTGCTTCGTGCTCCTGTGCGGAGTAGTGGATTTCGCCAGAAGTTTGAGTATCACTACTCCTGAAGAGATGATTGAA
AAAGCCAAAGGGGAAACTGCCTATCTGCCATGCAAATTTACGCTTAGTCCCGAAGACCAGGGACCGCTGGACATCGAGTGGCTGATATCA
CCAGCTGATAATCAGAAGGTGGATCAAGTGATTATTTTATATTCTGGAGACAAAATTTATGATGACTACTATCCAGATCTGAAAGGCCGA
GTACATTTTACGAGTAATGATCTCAAATCTGGTGATGCATCAATAAATGTAACGAATTTACAACTGTCAGATATTGGCACATATCAGTGC
AAAGTGAAAAAAGCTCCTGGTGTTGCAAATAAGAAGATTCATCTGGTAGTTCTTGGGAAGATGTGCCACCTCCAAAGAGCCGTACGTCCA
CTGCCAGAAGCTACATCGGCAGTAATCATTCATCCCTGGGGTCCATGTCTCCTTCCAACATGGAAGGATATTCCAAGACTCAGTATAACC
AAGTACCAAGTGAAGACTTTGAACGCACTCCTCAGAGTCCGACTCTCCCACCTGCTAAGGTAGGATCCATGCTTGAAGCTGGATGAAACT
TCGCCGAGAGGAGAGGAGTATCAAGATAAGTTAGCAGCTGAAGAAGGAACCAGCAGTGATGAAGAAGAAAGGACCAAAGTGCTTCTCAAG
GAGGGAAGTGACCCACAACCTCCACTGGGCTCTTTGTTGAAGGAGAAAACATCCAAAATCCAGCGTCTAGAGGAGGACTGGCAAAGCCAG
AAGGCCAAATTGCAAGCCCAGGTCTCACAGATGCAGCAGGCTCTGGAGCAGTGCACCAGCAACTACAGGGAGGACCTGCAGGCACTCAAG
CAGCTCTCGGACCTGGAGAGGGAGAAGCTGCAGCGTGAGCTCCAGGAGACCACTCAGCAGAACCACGCCATGAAAGCCCAGCTCGAGGCT
TCCCACCAGAGAGCCCTGCGCATGCTGGAGAAGGCCAGACATCAGGAACTCAAGGCCACAGAGGAACGCTTGAAGAAGGAATCCAGCCAC
AGCCTCCAGATCCAACACCAGACACACCGACTGGAGCTCCAGGCCTTGGAGGAAAAGGCCAGGCAAGAGCTGCAGGAGGAGCGTGAGAGG
ATGCAGGCACAGCAGGCCCTGCTGCTAGAGTCGCTCAGACAGGAGCTGTCGGAGCAGCAAGCTGCCTGTTCTGGGCACCAGAAGGACTTG
GAGGCACTGCAGGCCGAGCTGAGGGCTCTGGGCAGACAGCAAGCCAGCAGCCAGTGTCCAGGAGACAGCAAGGATCACATAATCGCCACA
GAGGAGCGGGGCGGCCCGGGCCAGGCCGGCTCCCCACCGGGCGCTGCTGGGCAGGGTTCCGGCGAGGGATGCGGGCTCTGGGAGGAGAAC
GCGCAGCTCCAGGACGCGGTGCGGCGGCTGCGCGCGGAGGTGGAGCAGCATCAGCAGGAGGCGCAGAAGCTCCGAGACCAGCGCAGGTTC
CTGGAGGAGACTCAGCAAGCCCAGCGGGCCAGGGAGGTGGAGACACTGCGCCAGGAACACCGGAAGGAGATGCAGGCCATGGTGGCAGAT
TTCAGTAGTGCCCAGGCCCAGCTCCAGGCCCGGCTGGCTGCCCTGGAAGCCGAACTGAAAGATTCCGGAGAGAAGCCAGGGAAGGGAGCG
TCCAGGCCCGAGGACCTTCAGCTCATTGGCCGCCTGCAGACCCGCCTGAAGGAGAGAGAGGACATCATCAAGCAGCTCACGGAAGAGAGA
AGATTTCACTACGCAGCATTCCCCAGTGCCATGTCCCACCGGAATCGGTCTTTCTCTTTCAATCCTCACCCGGGATATTTGACCCCTTCC
ATGAAGAAAAAGAAGGTGGAGGACGTGCCCAGCCGCGTGGTCAGCGTGCCGAACCTCGCCTCCTATGCAAAGAACTTTCTGAGTGGCGAT
CTGAGTTCCAGGATTAATGCCCCTCCAATAACTACATCACCCAGCTTGGACCCAAGCCCCAGCTGTGGCCGGACCTACAAACCCAACCAG
TCTACAGATGCAAAAACTGCCACAAGGACCCCAGATGGTGAAACGGCCCAAGCCAAAGAAGTCCAGCAGAAACAGGGCTCTCCGCACCAG
GAATGGTTCACCAAGTACTTTTCTTTCTAAGCTAACCTTTGGGATACATCACAGAGGATACTTGAAAAACATTTATTTTAAATCATCCGA
TTGAAGGAATGAACTAACACCAACCAACCAAATAATATGCTTATGATTTATATATGATAGCTAAAACAAATTTTGGCGTTAACACTTCAT
ACTGTTCTGCCAGGCACAGCAGCTCACGCCTGTAATCCCATCACTTTGGGAGGCTGAGGCAGATGGACTGCTTGAGTCCAGGAATTTGAG
ACCAGCCTGGCCAATATGGTGAAACCCCATCTCTACAAAATATACAAAAATTAGCCAGGCATGGTGGCGTGTGCCTGTGGTCCCAGGTAC
TTGGGGGACTGAGGCGGGAGGATCACTTGAACCTAGGAGGCAGAGGTTGCAGTGAGCCAAGTTCGAACTCCTGCATTCCAACCAGCCTGG
GTGACAGAGGGAGACCCTGTCTCCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATTGACATTAAACCAGTGTTATT
AAAAGTCATCTATAGGAAAATGTTATTAGCGTTACTAATGACCCATACCTTGTATTTCTAGTGTCCATAACATCATACTCCATTTTGTGG
AACATCAGACTTTGTGATTTCCATGATCTATTTCAAAAGTGGTTGTACTTGTCCTTAGGATGCTAGTCAACTCCACTGGAAAGCTGTTTC
TATGTAAAATGATGCAATTCCAAAATGCACATCTAACCTCAATAGGAAGACAAATAACAGTTAAACAGGAAAGCCAACTAAAAACAAACC
AAACCTACCAGAAATGGATGGTAGCATGCTTGGACTGAATACTTTCACTTCCTTGGTCTAAGACAAGCAGCAGATTATAGATGGGATAAC
ACCCACCTCTAAAAGGGCTTTGCAAGGATTAAGCAAGATAACATAAATTAACATGAATTGGAATTAAGTACCACAAGGTTTTTCTGTAAA
TAACCAATCCTAGCCCAGTTATAGGTCTCAGTGTAATGACCATAGTGCCAACATGATCACTTGTGAAGGTCTCTAGATTATCTGTTCTTT
GAAGTCAAAGATCTTCTAGACTGGGCACATGGCTCATGCCTGTAATCCCAACACTTTGGGAGGCTGAGATGGGAGGAGAGCTTGAGGCCA
GGAATTTGAGACCAGCCTGGGCAACACAGCGAGACCTCCATCTCTACAAAAAAATAATTAGCCCAAAGAAAACCCAGCTACTTGGAAGTC
TGAGGTAGGACAGCATGAGCCCAAGAGTTCGAGACCAGCCTGGGCAAGATAGTGAGATCCCATCTCTACAGATTAAAAAAATATATATAT
ATATCCCCTGAACCTCTGGTCTTTGGGTTTGAGCCATTTGCCTCATGGTGTGTTGCTTCTTCACTGCATGAATTCCCAGTGGGTTAAAGG
AACCGCAATGGCTGTTCACGGTGCTGACCTTGCTCTCAGTCCACACTGATTTGTCTTACCTTCTGACAGAGCAATGTGATTTGACAAGAC
TCAATAACAACTTTTAGGGGGCAAAATATTTTTTCAGTCTTTGGTGCTGGCCCAGAAGGTGGCCCACAAACCAATGTTAATTCTATGCAT
TGTCAAATCTTTGCTCTTTGAATAAAACTTTGAATAACTGGGCAATAAAAATGGTTGACTTGTATTGATTTTCCACAGAAAGGTAAAATT
AGATGAAGACAGCTTAGAAATAGAAAGTTCAGTTCACATTAACCTCAATCACACCATCTTAAAAAAAAAAAAGCTGATTACATATAACTG
TCAAACTTACGTATTAAAGGTAAATTTACTGCCTAATCAAAACGAGGCTCCAATGCATTTTTAAATGCAAACAAACACTTGTCACCATAC
ATTAACACACCATACTGTTTTTCACTACCAAATATTTTTTGTGAGTTTCCCGCTTAGAGTGTCTTAGTTCGTTCAGGCTGCTCTAACAAA
ATATCTTACTTATACTGGATAATTTATAAACAATAGAAATATGTCACTCACAGTCCTAGAGGCTAAGTCCAAGATCAAGGCACCAGCAGA
TATGGAGTCTGGGGAGGGCCCATTCTTCAGAAATGGGTGCCTGCTACGTGTCCTTACATGGTGGAAGAGGCAAGAGCGCCTCCCTGAGCC
TCTTTTGTAAGGGTACTTATCCTACTCATGAGGGTGAAGCCCTCATGACTCCATTGCTTCCCAAAAGCCCCACCTCTTAATACTATTACA
TTGACATTAGGTTCCAACATATGAATTTTGGAAGGGACATCAACATTCAGGACATAGCAGTGAACCCTGTAGGACTGCTCTTTATTTTGT
GCTTTCAAAAAGACTACATACAGGTGGTTCTATTTTTGTGTGTTGAAACACTTTCCCAGGCTGCACTTTGCATTTCTGTCCTTAAACTCA
GCATGATCCCTGGGCAAGGAGAAAATTTTACTAGTTGAGATCGTACATAGGTTTTGACTCCTTTCTTGCTGCAGGTGACTGAAAAGATCT
TTCAGTCTTAAATTTCTAAATTCTACCCTGCAATGATTATATCTTTGTTAACAAAATCTTTGCATGCTTCCATAATTTTTTATTGAGGCC
ATATGCCTTGGGTATTGAAGTAAGGCATTTAAGGACACAAACTTAAGCTTTTTGTTTGTTATTACCAAACTGCCATTCAGAAAGTTTCTA
ACAATTTACACCCTTACCAGCAGTAAATGAACCTACTGTGCCCTAACACTATTGACAAAGAAATACAATTTGATAGATAAAACATTCTAT
TTTAGTTTGCATAATGATTCCATCAATCTCTCAACAGCAGAGCGGTCTAGAGATGACAGTGATGGCGTAGAGGTGACAGTGAAGATGAAG
AGAAATTATCCAATTCGGGATTAAGTTAAGAGAGAGAAAAAAACAGTATTTAATGGTAAATCTCTTCAGGCTGTATTATGACAGGGGTGG
AAGAGTTAATATGTTCCTGCAGCAAAACTGAAAGGAATACTATCTGTTCCACATGAAAGCAAACTGTTTTGTAATTGGGGTAGGTAAAAA
TGGATTCACCCAGTCAATGGCTGCACACCACATACCTGAGCCCTTAACTGCTCTAACACTGATGTAATATCCAACCCAACATTTGTGATT
GAGGCTACTTGGTTAATTTTTCTCCAGGATCCATCTGGATTCTGCAGATGAGGCTGGCAAATTAAATGGAACTATGATAGGGACCATCTT

>20802_20802_2_CXADR-FAM184B_CXADR_chr21_18937929_ENST00000400165_FAM184B_chr4_17666282_ENST00000265018_length(amino acids)=525AA_BP=
MKLDETSPRGEEYQDKLAAEEGTSSDEEERTKVLLKEGSDPQPPLGSLLKEKTSKIQRLEEDWQSQKAKLQAQVSQMQQALEQCTSNYRE
DLQALKQLSDLEREKLQRELQETTQQNHAMKAQLEASHQRALRMLEKARHQELKATEERLKKESSHSLQIQHQTHRLELQALEEKARQEL
QEERERMQAQQALLLESLRQELSEQQAACSGHQKDLEALQAELRALGRQQASSQCPGDSKDHIIATEERGGPGQAGSPPGAAGQGSGEGC
GLWEENAQLQDAVRRLRAEVEQHQQEAQKLRDQRRFLEETQQAQRAREVETLRQEHRKEMQAMVADFSSAQAQLQARLAALEAELKDSGE
KPGKGASRPEDLQLIGRLQTRLKEREDIIKQLTEERRFHYAAFPSAMSHRNRSFSFNPHPGYLTPSMKKKKVEDVPSRVVSVPNLASYAK

--------------------------------------------------------------
>20802_20802_3_CXADR-FAM184B_CXADR_chr21_18937929_ENST00000400166_FAM184B_chr4_17666282_ENST00000265018_length(transcript)=5709nt_BP=896nt
CGGGAGCGCGCGAGGCGCGGGGAGCCTGGGACCAGGAGCGAGAGCCGCCTACCTGCAGCCGCCGCCCACGGCACGGCAGCCACCATGGCG
CTCCTGCTGTGCTTCGTGCTCCTGTGCGGAGTAGTGGATTTCGCCAGAAGTTTGAGTATCACTACTCCTGAAGAGATGATTGAAAAAGCC
AAAGGGGAAACTGCCTATCTGCCATGCAAATTTACGCTTAGTCCCGAAGACCAGGGACCGCTGGACATCGAGTGGCTGATATCACCAGCT
GATAATCAGAAGGTGGATCAAGTGATTATTTTATATTCTGGAGACAAAATTTATGATGACTACTATCCAGATCTGAAAGGCCGAGTACAT
TTTACGAGTAATGATCTCAAATCTGGTGATGCATCAATAAATGTAACGAATTTACAACTGTCAGATATTGGCACATATCAGTGCAAAGTG
AAAAAAGCTCCTGGTGTTGCAAATAAGAAGATTCATCTGGTAGTTCTTGTTAAGCCTTCAGGTGCGAGATGTTACGTTGATGGATCTGAA
GAAATTGGAAGTGACTTTAAGATAAAATGTGAACCAAAAGAAGGTTCACTTCCATTACAGTATGAGTGGCAAAAATTGTCTGACTCACAG
AAAATGCCCACTTCATGGTTAGCAGGTAGCTGCCCCTAATCTAAGTCGAATGGGTGCGATTCCTGTGATGATTCCAGCACAGAGCAAGGA
TGGGTCTATAGTATAGAGCCTCCATATGTCTCATCTGTGCTCTCCGTGTTCCTTTCCTTTTTTTGATATATGAAAACCTATTCTGGTCTA
AATTGTGTTACTAGCCTCAAAATACATCAAAAAATAAGTTAATCAGGAACTGTACGGAATATATTTTTAAAAATTTTTGTTTGGTTGATC
CATGCTTGAAGCTGGATGAAACTTCGCCGAGAGGAGAGGAGTATCAAGATAAGTTAGCAGCTGAAGAAGGAACCAGCAGTGATGAAGAAG
AAAGGACCAAAGTGCTTCTCAAGGAGGGAAGTGACCCACAACCTCCACTGGGCTCTTTGTTGAAGGAGAAAACATCCAAAATCCAGCGTC
TAGAGGAGGACTGGCAAAGCCAGAAGGCCAAATTGCAAGCCCAGGTCTCACAGATGCAGCAGGCTCTGGAGCAGTGCACCAGCAACTACA
GGGAGGACCTGCAGGCACTCAAGCAGCTCTCGGACCTGGAGAGGGAGAAGCTGCAGCGTGAGCTCCAGGAGACCACTCAGCAGAACCACG
CCATGAAAGCCCAGCTCGAGGCTTCCCACCAGAGAGCCCTGCGCATGCTGGAGAAGGCCAGACATCAGGAACTCAAGGCCACAGAGGAAC
GCTTGAAGAAGGAATCCAGCCACAGCCTCCAGATCCAACACCAGACACACCGACTGGAGCTCCAGGCCTTGGAGGAAAAGGCCAGGCAAG
AGCTGCAGGAGGAGCGTGAGAGGATGCAGGCACAGCAGGCCCTGCTGCTAGAGTCGCTCAGACAGGAGCTGTCGGAGCAGCAAGCTGCCT
GTTCTGGGCACCAGAAGGACTTGGAGGCACTGCAGGCCGAGCTGAGGGCTCTGGGCAGACAGCAAGCCAGCAGCCAGTGTCCAGGAGACA
GCAAGGATCACATAATCGCCACAGAGGAGCGGGGCGGCCCGGGCCAGGCCGGCTCCCCACCGGGCGCTGCTGGGCAGGGTTCCGGCGAGG
GATGCGGGCTCTGGGAGGAGAACGCGCAGCTCCAGGACGCGGTGCGGCGGCTGCGCGCGGAGGTGGAGCAGCATCAGCAGGAGGCGCAGA
AGCTCCGAGACCAGCGCAGGTTCCTGGAGGAGACTCAGCAAGCCCAGCGGGCCAGGGAGGTGGAGACACTGCGCCAGGAACACCGGAAGG
AGATGCAGGCCATGGTGGCAGATTTCAGTAGTGCCCAGGCCCAGCTCCAGGCCCGGCTGGCTGCCCTGGAAGCCGAACTGAAAGATTCCG
GAGAGAAGCCAGGGAAGGGAGCGTCCAGGCCCGAGGACCTTCAGCTCATTGGCCGCCTGCAGACCCGCCTGAAGGAGAGAGAGGACATCA
TCAAGCAGCTCACGGAAGAGAGAAGATTTCACTACGCAGCATTCCCCAGTGCCATGTCCCACCGGAATCGGTCTTTCTCTTTCAATCCTC
ACCCGGGATATTTGACCCCTTCCATGAAGAAAAAGAAGGTGGAGGACGTGCCCAGCCGCGTGGTCAGCGTGCCGAACCTCGCCTCCTATG
CAAAGAACTTTCTGAGTGGCGATCTGAGTTCCAGGATTAATGCCCCTCCAATAACTACATCACCCAGCTTGGACCCAAGCCCCAGCTGTG
GCCGGACCTACAAACCCAACCAGTCTACAGATGCAAAAACTGCCACAAGGACCCCAGATGGTGAAACGGCCCAAGCCAAAGAAGTCCAGC
AGAAACAGGGCTCTCCGCACCAGGAATGGTTCACCAAGTACTTTTCTTTCTAAGCTAACCTTTGGGATACATCACAGAGGATACTTGAAA
AACATTTATTTTAAATCATCCGATTGAAGGAATGAACTAACACCAACCAACCAAATAATATGCTTATGATTTATATATGATAGCTAAAAC
AAATTTTGGCGTTAACACTTCATACTGTTCTGCCAGGCACAGCAGCTCACGCCTGTAATCCCATCACTTTGGGAGGCTGAGGCAGATGGA
CTGCTTGAGTCCAGGAATTTGAGACCAGCCTGGCCAATATGGTGAAACCCCATCTCTACAAAATATACAAAAATTAGCCAGGCATGGTGG
CGTGTGCCTGTGGTCCCAGGTACTTGGGGGACTGAGGCGGGAGGATCACTTGAACCTAGGAGGCAGAGGTTGCAGTGAGCCAAGTTCGAA
CTCCTGCATTCCAACCAGCCTGGGTGACAGAGGGAGACCCTGTCTCCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
ATTGACATTAAACCAGTGTTATTAAAAGTCATCTATAGGAAAATGTTATTAGCGTTACTAATGACCCATACCTTGTATTTCTAGTGTCCA
TAACATCATACTCCATTTTGTGGAACATCAGACTTTGTGATTTCCATGATCTATTTCAAAAGTGGTTGTACTTGTCCTTAGGATGCTAGT
CAACTCCACTGGAAAGCTGTTTCTATGTAAAATGATGCAATTCCAAAATGCACATCTAACCTCAATAGGAAGACAAATAACAGTTAAACA
GGAAAGCCAACTAAAAACAAACCAAACCTACCAGAAATGGATGGTAGCATGCTTGGACTGAATACTTTCACTTCCTTGGTCTAAGACAAG
CAGCAGATTATAGATGGGATAACACCCACCTCTAAAAGGGCTTTGCAAGGATTAAGCAAGATAACATAAATTAACATGAATTGGAATTAA
GTACCACAAGGTTTTTCTGTAAATAACCAATCCTAGCCCAGTTATAGGTCTCAGTGTAATGACCATAGTGCCAACATGATCACTTGTGAA
GGTCTCTAGATTATCTGTTCTTTGAAGTCAAAGATCTTCTAGACTGGGCACATGGCTCATGCCTGTAATCCCAACACTTTGGGAGGCTGA
GATGGGAGGAGAGCTTGAGGCCAGGAATTTGAGACCAGCCTGGGCAACACAGCGAGACCTCCATCTCTACAAAAAAATAATTAGCCCAAA
GAAAACCCAGCTACTTGGAAGTCTGAGGTAGGACAGCATGAGCCCAAGAGTTCGAGACCAGCCTGGGCAAGATAGTGAGATCCCATCTCT
ACAGATTAAAAAAATATATATATATATCCCCTGAACCTCTGGTCTTTGGGTTTGAGCCATTTGCCTCATGGTGTGTTGCTTCTTCACTGC
ATGAATTCCCAGTGGGTTAAAGGAACCGCAATGGCTGTTCACGGTGCTGACCTTGCTCTCAGTCCACACTGATTTGTCTTACCTTCTGAC
AGAGCAATGTGATTTGACAAGACTCAATAACAACTTTTAGGGGGCAAAATATTTTTTCAGTCTTTGGTGCTGGCCCAGAAGGTGGCCCAC
AAACCAATGTTAATTCTATGCATTGTCAAATCTTTGCTCTTTGAATAAAACTTTGAATAACTGGGCAATAAAAATGGTTGACTTGTATTG
ATTTTCCACAGAAAGGTAAAATTAGATGAAGACAGCTTAGAAATAGAAAGTTCAGTTCACATTAACCTCAATCACACCATCTTAAAAAAA
AAAAAGCTGATTACATATAACTGTCAAACTTACGTATTAAAGGTAAATTTACTGCCTAATCAAAACGAGGCTCCAATGCATTTTTAAATG
CAAACAAACACTTGTCACCATACATTAACACACCATACTGTTTTTCACTACCAAATATTTTTTGTGAGTTTCCCGCTTAGAGTGTCTTAG
TTCGTTCAGGCTGCTCTAACAAAATATCTTACTTATACTGGATAATTTATAAACAATAGAAATATGTCACTCACAGTCCTAGAGGCTAAG
TCCAAGATCAAGGCACCAGCAGATATGGAGTCTGGGGAGGGCCCATTCTTCAGAAATGGGTGCCTGCTACGTGTCCTTACATGGTGGAAG
AGGCAAGAGCGCCTCCCTGAGCCTCTTTTGTAAGGGTACTTATCCTACTCATGAGGGTGAAGCCCTCATGACTCCATTGCTTCCCAAAAG
CCCCACCTCTTAATACTATTACATTGACATTAGGTTCCAACATATGAATTTTGGAAGGGACATCAACATTCAGGACATAGCAGTGAACCC
TGTAGGACTGCTCTTTATTTTGTGCTTTCAAAAAGACTACATACAGGTGGTTCTATTTTTGTGTGTTGAAACACTTTCCCAGGCTGCACT
TTGCATTTCTGTCCTTAAACTCAGCATGATCCCTGGGCAAGGAGAAAATTTTACTAGTTGAGATCGTACATAGGTTTTGACTCCTTTCTT
GCTGCAGGTGACTGAAAAGATCTTTCAGTCTTAAATTTCTAAATTCTACCCTGCAATGATTATATCTTTGTTAACAAAATCTTTGCATGC
TTCCATAATTTTTTATTGAGGCCATATGCCTTGGGTATTGAAGTAAGGCATTTAAGGACACAAACTTAAGCTTTTTGTTTGTTATTACCA
AACTGCCATTCAGAAAGTTTCTAACAATTTACACCCTTACCAGCAGTAAATGAACCTACTGTGCCCTAACACTATTGACAAAGAAATACA
ATTTGATAGATAAAACATTCTATTTTAGTTTGCATAATGATTCCATCAATCTCTCAACAGCAGAGCGGTCTAGAGATGACAGTGATGGCG
TAGAGGTGACAGTGAAGATGAAGAGAAATTATCCAATTCGGGATTAAGTTAAGAGAGAGAAAAAAACAGTATTTAATGGTAAATCTCTTC
AGGCTGTATTATGACAGGGGTGGAAGAGTTAATATGTTCCTGCAGCAAAACTGAAAGGAATACTATCTGTTCCACATGAAAGCAAACTGT
TTTGTAATTGGGGTAGGTAAAAATGGATTCACCCAGTCAATGGCTGCACACCACATACCTGAGCCCTTAACTGCTCTAACACTGATGTAA
TATCCAACCCAACATTTGTGATTGAGGCTACTTGGTTAATTTTTCTCCAGGATCCATCTGGATTCTGCAGATGAGGCTGGCAAATTAAAT

>20802_20802_3_CXADR-FAM184B_CXADR_chr21_18937929_ENST00000400166_FAM184B_chr4_17666282_ENST00000265018_length(amino acids)=530AA_BP=2
MVDPCLKLDETSPRGEEYQDKLAAEEGTSSDEEERTKVLLKEGSDPQPPLGSLLKEKTSKIQRLEEDWQSQKAKLQAQVSQMQQALEQCT
SNYREDLQALKQLSDLEREKLQRELQETTQQNHAMKAQLEASHQRALRMLEKARHQELKATEERLKKESSHSLQIQHQTHRLELQALEEK
ARQELQEERERMQAQQALLLESLRQELSEQQAACSGHQKDLEALQAELRALGRQQASSQCPGDSKDHIIATEERGGPGQAGSPPGAAGQG
SGEGCGLWEENAQLQDAVRRLRAEVEQHQQEAQKLRDQRRFLEETQQAQRAREVETLRQEHRKEMQAMVADFSSAQAQLQARLAALEAEL
KDSGEKPGKGASRPEDLQLIGRLQTRLKEREDIIKQLTEERRFHYAAFPSAMSHRNRSFSFNPHPGYLTPSMKKKKVEDVPSRVVSVPNL

--------------------------------------------------------------
>20802_20802_4_CXADR-FAM184B_CXADR_chr21_18937929_ENST00000400169_FAM184B_chr4_17666282_ENST00000265018_length(transcript)=5830nt_BP=1017nt
ATGGCGCTCCTGCTGTGCTTCGTGCTCCTGTGCGGAGTAGTGGATTTCGCCAGAAGTTTGAGTATCACTACTCCTGAAGAGATGATTGAA
AAAGCCAAAGGGGAAACTGCCTATCTGCCATGCAAATTTACGCTTAGTCCCGAAGACCAGGGACCGCTGGACATCGAGTGGCTGATATCA
CCAGCTGATAATCAGAAGGTGGATCAAGTGATTATTTTATATTCTGGAGACAAAATTTATGATGACTACTATCCAGATCTGAAAGGCCGA
GTACATTTTACGAGTAATGATCTCAAATCTGGTGATGCATCAATAAATGTAACGAATTTACAACTGTCAGATATTGGCACATATCAGTGC
AAAGTGAAAAAAGCTCCTGGTGTTGCAAATAAGAAGATTCATCTGGTAGTTCTTGTTAAGCCTTCAGGTGCGAGATGTTACGTTGATGGA
TCTGAAGAAATTGGAAGTGACTTTAAGATAAAATGTGAACCAAAAGAAGGTTCACTTCCATTACAGTATGAGTGGCAAAAATTGTCTGAC
TCACAGAAAATGCCCACTTCATGGTTAGCAGAAATGACTTCATCTGTTATATCTGTAAAAAATGCCTCTTCTGAGTACTCTGGGACATAC
AGCTGTACAGTCAGAAACAGAGTGGGCTCTGATCAGTGCCTGTTGCGTCTAAACGTTGTCCCTCCTTCAAATAAAGCTGGACTAATTGCA
GGAGCCATTATAGGAACTTTGCTTGCTCTAGCGCTCATTGGTCTTATCATCTTTTGCTGTCGTAAAAAGCGCAGAGAAGAAAAATATGAA
AAGGAAGTTCATCACGATATCAGGGAAGATGTGCCACCTCCAAAGAGCCGTACGTCCACTGCCAGAAGCTACATCGGCAGTAATCATTCA
TCCCTGGGGTCCATGTCTCCTTCCAACATGGAAGGATATTCCAAGACTCAGTATAACCAAGTACCAAGTGAAGACTTTGAACGCACTCCT
CAGAGTCCGACTCTCCCACCTGCTAAGGATCCATGCTTGAAGCTGGATGAAACTTCGCCGAGAGGAGAGGAGTATCAAGATAAGTTAGCA
GCTGAAGAAGGAACCAGCAGTGATGAAGAAGAAAGGACCAAAGTGCTTCTCAAGGAGGGAAGTGACCCACAACCTCCACTGGGCTCTTTG
TTGAAGGAGAAAACATCCAAAATCCAGCGTCTAGAGGAGGACTGGCAAAGCCAGAAGGCCAAATTGCAAGCCCAGGTCTCACAGATGCAG
CAGGCTCTGGAGCAGTGCACCAGCAACTACAGGGAGGACCTGCAGGCACTCAAGCAGCTCTCGGACCTGGAGAGGGAGAAGCTGCAGCGT
GAGCTCCAGGAGACCACTCAGCAGAACCACGCCATGAAAGCCCAGCTCGAGGCTTCCCACCAGAGAGCCCTGCGCATGCTGGAGAAGGCC
AGACATCAGGAACTCAAGGCCACAGAGGAACGCTTGAAGAAGGAATCCAGCCACAGCCTCCAGATCCAACACCAGACACACCGACTGGAG
CTCCAGGCCTTGGAGGAAAAGGCCAGGCAAGAGCTGCAGGAGGAGCGTGAGAGGATGCAGGCACAGCAGGCCCTGCTGCTAGAGTCGCTC
AGACAGGAGCTGTCGGAGCAGCAAGCTGCCTGTTCTGGGCACCAGAAGGACTTGGAGGCACTGCAGGCCGAGCTGAGGGCTCTGGGCAGA
CAGCAAGCCAGCAGCCAGTGTCCAGGAGACAGCAAGGATCACATAATCGCCACAGAGGAGCGGGGCGGCCCGGGCCAGGCCGGCTCCCCA
CCGGGCGCTGCTGGGCAGGGTTCCGGCGAGGGATGCGGGCTCTGGGAGGAGAACGCGCAGCTCCAGGACGCGGTGCGGCGGCTGCGCGCG
GAGGTGGAGCAGCATCAGCAGGAGGCGCAGAAGCTCCGAGACCAGCGCAGGTTCCTGGAGGAGACTCAGCAAGCCCAGCGGGCCAGGGAG
GTGGAGACACTGCGCCAGGAACACCGGAAGGAGATGCAGGCCATGGTGGCAGATTTCAGTAGTGCCCAGGCCCAGCTCCAGGCCCGGCTG
GCTGCCCTGGAAGCCGAACTGAAAGATTCCGGAGAGAAGCCAGGGAAGGGAGCGTCCAGGCCCGAGGACCTTCAGCTCATTGGCCGCCTG
CAGACCCGCCTGAAGGAGAGAGAGGACATCATCAAGCAGCTCACGGAAGAGAGAAGATTTCACTACGCAGCATTCCCCAGTGCCATGTCC
CACCGGAATCGGTCTTTCTCTTTCAATCCTCACCCGGGATATTTGACCCCTTCCATGAAGAAAAAGAAGGTGGAGGACGTGCCCAGCCGC
GTGGTCAGCGTGCCGAACCTCGCCTCCTATGCAAAGAACTTTCTGAGTGGCGATCTGAGTTCCAGGATTAATGCCCCTCCAATAACTACA
TCACCCAGCTTGGACCCAAGCCCCAGCTGTGGCCGGACCTACAAACCCAACCAGTCTACAGATGCAAAAACTGCCACAAGGACCCCAGAT
GGTGAAACGGCCCAAGCCAAAGAAGTCCAGCAGAAACAGGGCTCTCCGCACCAGGAATGGTTCACCAAGTACTTTTCTTTCTAAGCTAAC
CTTTGGGATACATCACAGAGGATACTTGAAAAACATTTATTTTAAATCATCCGATTGAAGGAATGAACTAACACCAACCAACCAAATAAT
ATGCTTATGATTTATATATGATAGCTAAAACAAATTTTGGCGTTAACACTTCATACTGTTCTGCCAGGCACAGCAGCTCACGCCTGTAAT
CCCATCACTTTGGGAGGCTGAGGCAGATGGACTGCTTGAGTCCAGGAATTTGAGACCAGCCTGGCCAATATGGTGAAACCCCATCTCTAC
AAAATATACAAAAATTAGCCAGGCATGGTGGCGTGTGCCTGTGGTCCCAGGTACTTGGGGGACTGAGGCGGGAGGATCACTTGAACCTAG
GAGGCAGAGGTTGCAGTGAGCCAAGTTCGAACTCCTGCATTCCAACCAGCCTGGGTGACAGAGGGAGACCCTGTCTCCAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAATTGACATTAAACCAGTGTTATTAAAAGTCATCTATAGGAAAATGTTATTAGCGTTACT
AATGACCCATACCTTGTATTTCTAGTGTCCATAACATCATACTCCATTTTGTGGAACATCAGACTTTGTGATTTCCATGATCTATTTCAA
AAGTGGTTGTACTTGTCCTTAGGATGCTAGTCAACTCCACTGGAAAGCTGTTTCTATGTAAAATGATGCAATTCCAAAATGCACATCTAA
CCTCAATAGGAAGACAAATAACAGTTAAACAGGAAAGCCAACTAAAAACAAACCAAACCTACCAGAAATGGATGGTAGCATGCTTGGACT
GAATACTTTCACTTCCTTGGTCTAAGACAAGCAGCAGATTATAGATGGGATAACACCCACCTCTAAAAGGGCTTTGCAAGGATTAAGCAA
GATAACATAAATTAACATGAATTGGAATTAAGTACCACAAGGTTTTTCTGTAAATAACCAATCCTAGCCCAGTTATAGGTCTCAGTGTAA
TGACCATAGTGCCAACATGATCACTTGTGAAGGTCTCTAGATTATCTGTTCTTTGAAGTCAAAGATCTTCTAGACTGGGCACATGGCTCA
TGCCTGTAATCCCAACACTTTGGGAGGCTGAGATGGGAGGAGAGCTTGAGGCCAGGAATTTGAGACCAGCCTGGGCAACACAGCGAGACC
TCCATCTCTACAAAAAAATAATTAGCCCAAAGAAAACCCAGCTACTTGGAAGTCTGAGGTAGGACAGCATGAGCCCAAGAGTTCGAGACC
AGCCTGGGCAAGATAGTGAGATCCCATCTCTACAGATTAAAAAAATATATATATATATCCCCTGAACCTCTGGTCTTTGGGTTTGAGCCA
TTTGCCTCATGGTGTGTTGCTTCTTCACTGCATGAATTCCCAGTGGGTTAAAGGAACCGCAATGGCTGTTCACGGTGCTGACCTTGCTCT
CAGTCCACACTGATTTGTCTTACCTTCTGACAGAGCAATGTGATTTGACAAGACTCAATAACAACTTTTAGGGGGCAAAATATTTTTTCA
GTCTTTGGTGCTGGCCCAGAAGGTGGCCCACAAACCAATGTTAATTCTATGCATTGTCAAATCTTTGCTCTTTGAATAAAACTTTGAATA
ACTGGGCAATAAAAATGGTTGACTTGTATTGATTTTCCACAGAAAGGTAAAATTAGATGAAGACAGCTTAGAAATAGAAAGTTCAGTTCA
CATTAACCTCAATCACACCATCTTAAAAAAAAAAAAGCTGATTACATATAACTGTCAAACTTACGTATTAAAGGTAAATTTACTGCCTAA
TCAAAACGAGGCTCCAATGCATTTTTAAATGCAAACAAACACTTGTCACCATACATTAACACACCATACTGTTTTTCACTACCAAATATT
TTTTGTGAGTTTCCCGCTTAGAGTGTCTTAGTTCGTTCAGGCTGCTCTAACAAAATATCTTACTTATACTGGATAATTTATAAACAATAG
AAATATGTCACTCACAGTCCTAGAGGCTAAGTCCAAGATCAAGGCACCAGCAGATATGGAGTCTGGGGAGGGCCCATTCTTCAGAAATGG
GTGCCTGCTACGTGTCCTTACATGGTGGAAGAGGCAAGAGCGCCTCCCTGAGCCTCTTTTGTAAGGGTACTTATCCTACTCATGAGGGTG
AAGCCCTCATGACTCCATTGCTTCCCAAAAGCCCCACCTCTTAATACTATTACATTGACATTAGGTTCCAACATATGAATTTTGGAAGGG
ACATCAACATTCAGGACATAGCAGTGAACCCTGTAGGACTGCTCTTTATTTTGTGCTTTCAAAAAGACTACATACAGGTGGTTCTATTTT
TGTGTGTTGAAACACTTTCCCAGGCTGCACTTTGCATTTCTGTCCTTAAACTCAGCATGATCCCTGGGCAAGGAGAAAATTTTACTAGTT
GAGATCGTACATAGGTTTTGACTCCTTTCTTGCTGCAGGTGACTGAAAAGATCTTTCAGTCTTAAATTTCTAAATTCTACCCTGCAATGA
TTATATCTTTGTTAACAAAATCTTTGCATGCTTCCATAATTTTTTATTGAGGCCATATGCCTTGGGTATTGAAGTAAGGCATTTAAGGAC
ACAAACTTAAGCTTTTTGTTTGTTATTACCAAACTGCCATTCAGAAAGTTTCTAACAATTTACACCCTTACCAGCAGTAAATGAACCTAC
TGTGCCCTAACACTATTGACAAAGAAATACAATTTGATAGATAAAACATTCTATTTTAGTTTGCATAATGATTCCATCAATCTCTCAACA
GCAGAGCGGTCTAGAGATGACAGTGATGGCGTAGAGGTGACAGTGAAGATGAAGAGAAATTATCCAATTCGGGATTAAGTTAAGAGAGAG
AAAAAAACAGTATTTAATGGTAAATCTCTTCAGGCTGTATTATGACAGGGGTGGAAGAGTTAATATGTTCCTGCAGCAAAACTGAAAGGA
ATACTATCTGTTCCACATGAAAGCAAACTGTTTTGTAATTGGGGTAGGTAAAAATGGATTCACCCAGTCAATGGCTGCACACCACATACC
TGAGCCCTTAACTGCTCTAACACTGATGTAATATCCAACCCAACATTTGTGATTGAGGCTACTTGGTTAATTTTTCTCCAGGATCCATCT

>20802_20802_4_CXADR-FAM184B_CXADR_chr21_18937929_ENST00000400169_FAM184B_chr4_17666282_ENST00000265018_length(amino acids)=867AA_BP=339
MALLLCFVLLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKFTLSPEDQGPLDIEWLISPADNQKVDQVIILYSGDKIYDDYYPDLKGR
VHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPGVANKKIHLVVLVKPSGARCYVDGSEEIGSDFKIKCEPKEGSLPLQYEWQKLSD
SQKMPTSWLAEMTSSVISVKNASSEYSGTYSCTVRNRVGSDQCLLRLNVVPPSNKAGLIAGAIIGTLLALALIGLIIFCCRKKRREEKYE
KEVHHDIREDVPPPKSRTSTARSYIGSNHSSLGSMSPSNMEGYSKTQYNQVPSEDFERTPQSPTLPPAKDPCLKLDETSPRGEEYQDKLA
AEEGTSSDEEERTKVLLKEGSDPQPPLGSLLKEKTSKIQRLEEDWQSQKAKLQAQVSQMQQALEQCTSNYREDLQALKQLSDLEREKLQR
ELQETTQQNHAMKAQLEASHQRALRMLEKARHQELKATEERLKKESSHSLQIQHQTHRLELQALEEKARQELQEERERMQAQQALLLESL
RQELSEQQAACSGHQKDLEALQAELRALGRQQASSQCPGDSKDHIIATEERGGPGQAGSPPGAAGQGSGEGCGLWEENAQLQDAVRRLRA
EVEQHQQEAQKLRDQRRFLEETQQAQRAREVETLRQEHRKEMQAMVADFSSAQAQLQARLAALEAELKDSGEKPGKGASRPEDLQLIGRL
QTRLKEREDIIKQLTEERRFHYAAFPSAMSHRNRSFSFNPHPGYLTPSMKKKKVEDVPSRVVSVPNLASYAKNFLSGDLSSRINAPPITT

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for CXADR-FAM184B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for CXADR-FAM184B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for CXADR-FAM184B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource