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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CYB5B-SNTB2 (FusionGDB2 ID:20923)

Fusion Gene Summary for CYB5B-SNTB2

check button Fusion gene summary
Fusion gene informationFusion gene name: CYB5B-SNTB2
Fusion gene ID: 20923
HgeneTgene
Gene symbol

CYB5B

SNTB2

Gene ID

80777

6645

Gene namecytochrome b5 type Bsyntrophin beta 2
SynonymsCYB5-M|CYPB5M|OMB5D16S2531E|EST25263|SNT2B2|SNT3|SNTL
Cytomap

16q22.1

16q22.1

Type of geneprotein-codingprotein-coding
Descriptioncytochrome b5 type Bcytochrome b5 outer mitochondrial membrane isoformcytochrome b5 type B (outer mitochondrial membrane)outer mitochondrial membrane cytochrome b5type 2 cyt-b5beta-2-syntrophin59 kDa dystrophin-associated protein A1 basic component 2dystrophin-associated protein A1, 59kD, basic component 2syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)syntrophin-3
Modification date2020031320200313
UniProtAcc

O43169

.
Ensembl transtripts involved in fusion geneENST00000307892, ENST00000512062, 
ENST00000515314, ENST00000561792, 
ENST00000528525, ENST00000336278, 
Fusion gene scores* DoF score6 X 5 X 4=12018 X 15 X 13=3510
# samples 724
** MAII scorelog2(7/120*10)=-0.777607578663552
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(24/3510*10)=-3.8703647195834
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CYB5B [Title/Abstract] AND SNTB2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCYB5B(69458760)-SNTB2(69333493), # samples:1
CYB5B(69493024)-SNTB2(69293953), # samples:1
Anticipated loss of major functional domain due to fusion event.CYB5B-SNTB2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across CYB5B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SNTB2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ACCTCGA-OR-A5KX-01ACYB5Bchr16

69458760

+SNTB2chr16

69333493

+
ChimerDB4UCECTCGA-AJ-A3QS-01ACYB5Bchr16

69493024

+SNTB2chr16

69293953

+


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Fusion Gene ORF analysis for CYB5B-SNTB2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000307892ENST00000528525CYB5Bchr16

69458760

+SNTB2chr16

69333493

+
5CDS-intronENST00000307892ENST00000528525CYB5Bchr16

69493024

+SNTB2chr16

69293953

+
5CDS-intronENST00000512062ENST00000528525CYB5Bchr16

69458760

+SNTB2chr16

69333493

+
5CDS-intronENST00000512062ENST00000528525CYB5Bchr16

69493024

+SNTB2chr16

69293953

+
5CDS-intronENST00000515314ENST00000528525CYB5Bchr16

69458760

+SNTB2chr16

69333493

+
5CDS-intronENST00000561792ENST00000528525CYB5Bchr16

69458760

+SNTB2chr16

69333493

+
5CDS-intronENST00000561792ENST00000528525CYB5Bchr16

69493024

+SNTB2chr16

69293953

+
Frame-shiftENST00000307892ENST00000336278CYB5Bchr16

69458760

+SNTB2chr16

69333493

+
Frame-shiftENST00000512062ENST00000336278CYB5Bchr16

69458760

+SNTB2chr16

69333493

+
Frame-shiftENST00000515314ENST00000336278CYB5Bchr16

69458760

+SNTB2chr16

69333493

+
Frame-shiftENST00000561792ENST00000336278CYB5Bchr16

69458760

+SNTB2chr16

69333493

+
In-frameENST00000307892ENST00000336278CYB5Bchr16

69493024

+SNTB2chr16

69293953

+
In-frameENST00000512062ENST00000336278CYB5Bchr16

69493024

+SNTB2chr16

69293953

+
In-frameENST00000561792ENST00000336278CYB5Bchr16

69493024

+SNTB2chr16

69293953

+
intron-3CDSENST00000515314ENST00000336278CYB5Bchr16

69493024

+SNTB2chr16

69293953

+
intron-intronENST00000515314ENST00000528525CYB5Bchr16

69493024

+SNTB2chr16

69293953

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000512062CYB5Bchr1669493024+ENST00000336278SNTB2chr1669293953+94785211591349396
ENST00000307892CYB5Bchr1669493024+ENST00000336278SNTB2chr1669293953+9408451891279396
ENST00000561792CYB5Bchr1669493024+ENST00000336278SNTB2chr1669293953+932336641194396

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000512062ENST00000336278CYB5Bchr1669493024+SNTB2chr1669293953+0.0006659780.99933404
ENST00000307892ENST00000336278CYB5Bchr1669493024+SNTB2chr1669293953+0.000648850.9993512
ENST00000561792ENST00000336278CYB5Bchr1669493024+SNTB2chr1669293953+0.0006473940.99935263

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Fusion Genomic Features for CYB5B-SNTB2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
CYB5Bchr1669458760+SNTB2chr1669333492+1.50E-081
CYB5Bchr1669493024+SNTB2chr1669293952+6.66E-091
CYB5Bchr1669458760+SNTB2chr1669333492+1.50E-081
CYB5Bchr1669493024+SNTB2chr1669293952+6.66E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for CYB5B-SNTB2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr16:69458760/chr16:69333493)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CYB5B

O43169

.
FUNCTION: Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases. {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCYB5Bchr16:69493024chr16:69293953ENST00000512062+4524_100116147.0DomainCytochrome b5 heme-binding
TgeneSNTB2chr16:69493024chr16:69293953ENST0000033627817325_437264541.0DomainPH 2
TgeneSNTB2chr16:69493024chr16:69293953ENST0000033627817484_540264541.0DomainNote=SU
TgeneSNTB2chr16:69493024chr16:69293953ENST0000033627817518_540264541.0RegionCalmodulin-binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCYB5Bchr16:69493024chr16:69293953ENST00000512062+45123_140116147.0TransmembraneHelical
TgeneSNTB2chr16:69493024chr16:69293953ENST000003362781754_57264541.0Compositional biasNote=Poly-Ala
TgeneSNTB2chr16:69493024chr16:69293953ENST000003362781766_69264541.0Compositional biasNote=Poly-Ala
TgeneSNTB2chr16:69493024chr16:69293953ENST0000033627817115_198264541.0DomainPDZ
TgeneSNTB2chr16:69493024chr16:69293953ENST0000033627817163_300264541.0DomainPH 1


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Fusion Gene Sequence for CYB5B-SNTB2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>20923_20923_1_CYB5B-SNTB2_CYB5B_chr16_69493024_ENST00000307892_SNTB2_chr16_69293953_ENST00000336278_length(transcript)=9408nt_BP=451nt
TGGGCCCTGGTTACGGAAGCCGAGGAAGGCTGAGCGCGGGCTCTCAAGGAAAGTAGTCGCGGAATCTCAGTTAGCGGTGGAGAGGCAGTA
TGTCCGGTTCAATGGCGACTGCGGAAGCTAGCGGCAGCGATGGGAAAGGGCAGGAAGTCGAGACCTCAGTCACCTATTACCGGTTGGAGG
AGGTGGCAAAGCGCAACTCCTTGAAGGAACTGTGGCTTGTGATCCATGGGCGAGTCTACGATGTCACCCGCTTCCTCAACGAGCACCCTG
GAGGAGAAGAGGTTCTGCTGGAACAAGCTGGTGTAGATGCAAGTGAAAGCTTTGAAGATGTAGGACACTCTTCTGATGCCAGAGAAATGC
TAAAGCAGTACTACATTGGTGATATCCATCCGAGTGACCTTAAACCTGAAAGTGGTAGCAAGGACCCTTCAAAAAATGATACATGCAAAA
GATTGATAGAGCTACATTCTCCTGATAGCAGGAACACGTTGATCCTACGCTGCAAAGATACAGCCACAGCACACTCCTGGTTCGTAGCTA
TCCACACCAACATAATGGCTCTCCTCCCACAGGTGTTGGCTGAACTCAACGCCATGCTTGGGGCAACCAGTACAGCAGGAGGCAGTAAAG
AGGTGAAGCATATTGCCTGGCTGGCAGAACAGGCAAAACTAGATGGTGGAAGACAGCAATGGAGACCTGTCCTCATGGCTGTGACTGAGA
AGGATTTGCTGCTCTATGACTGTATGCCGTGGACAAGAGATGCCTGGGCGTCACCATGCCACAGCTACCCACTTGTTGCCACCAGGTTGG
TTCATTCTGGCTCCGGATGTCGATCCCCCTCCCTTGGATCTGACCTTACATTTGCTACCAGGACAGGCTCTCGACAGGGCATTGAGATGC
ATCTCTTCAGGGTGGAGACACATCGGGATCTGTCATCCTGGACCAGGATACTTGTTCAGGGTTGCCATGCTGCTGCTGAGCTGATCAAGG
AAGTCTCTCTAGGCTGCATGTTAAATGGCCAAGAGGTGAGGCTTACTATTCACTATGAAAATGGGTTCACCATCTCAAGGGAAAATGGAG
GCTCCAGCAGCATATTGTACCGCTACCCCTTTGAAAGGCTGAAGATGTCTGCTGATGATGGCATCCGAAATCTATACTTGGATTTTGGTG
GTCCCGAGGGAGAACTGACCATGGACCTGCACTCTTGTCCGAAGCCGATTGTATTTGTGTTGCACACGTTTTTATCGGCCAAAGTCACTC
GTATGGGACTGCTTGTATGAGCAACAAAAAATCAGAAAAGAGCCTTGACTGTCACAAGAAATATTTCCACCTCAAAAAAAAAAAAGCACA
AAAAGAAACTCTTTGCTCTCCTTCAGCACAGTGCCTTCCCAAGGACCTGCAAATAACTGCTGAACCATAACCGTGTTTAAAGAAGAGCCT
ACCTTTCACAGTCTACCTTGGCCAGATATTCTAGCACTCTAAAAGGCTCCAAAATGAAGCTGTTGATTTATTCTCATTTCAAAATATGGT
TTATGAGTAATTAGGTTTATTTCTACTGCTAAAAAGAATGGCTCATTGTTTTCTTTTTTTTTCATTGTTTTCATTTTTAGACATAATCAA
ATACCCAAGCATTGTTTTCTTTTTCTTCTCCCTGTAGGATTTGTGTTGTGCTTAGCCTTGATCTCTTGTTCAGAACAATTGTCCCTTCCC
AGGTGCTAGCTTGCAGCAGCCTGTTGCTTCCTGAGCATTCCAGATAGGTCGTATGTCTTGGAATTTACTGTCCTCACTAGCTCCTTCCAC
CATAGGAAGTCCTTGAATTGTATCACCAAAGGGTTGTTCCATTTGCCCTGGATCTCCCTCTATCTCAGCCTGGCCATCACTTCCCACCTT
ATCCCAAGCTTTGCCACTGTCTCTAGGACTTAGAACTTGTAAATTTGATTTGCCTTGCCTTCTACTTCCTTTCTAGTGGTGACTGAGTTG
AAAAGCAAGTTGGAAGCCACTGCTTTTAAAGAAAAGTTTTGCTTGGTTTAGGTTTTTCCAATTTTATTTTTGTTAGGAGCCAGGGGATAA
GATTTATTTTAAATGAAAATCCTCTTCCTAGGTTAAGCCATTTTTTTTATTGCTTACCAAATGTGCCTTTGGTTAGGGTTAGTGGAGCTT
TATTAGTCACTATTTGAATAACTGGAAATCACTGCCATTTCCAGGAGATCACCTATCCTAGTTTTGAGGAATAGTCATTGAGGTGGGTTT
CCTTAATGGCATCTCTTCTAGTAGGCAGATCTGTTTGAACAAGATAAATCCTAAAGAGCCAGCCTGCTTGAGGAGTAGACTTGGTGGGTG
AAGCCAGCAATTCCGCACAAACGTCATGTTGAATTGTTTTGGGCTGCCCAAAAACAACAGGATGCAGCATCCTGGCTGTGGCCTGGCCCT
TTGTGGCAGCAGTGGCATGGACAAGCAACTGCTAATTCGAGACTTACTATTGGCTTCACAGCACACCCTACAGTGAGCAGGGTGATGAGA
CCGTGGAACAGCTACCTGCTTTTGGTTAAGATTGCCAGATATCATTAGGACACAGTAGCAGCAAGAATGCTGATTTTGTAGTGTTAGAAA
ATGAACTCAGCTTGTTTTTCCTAATTTTGAAGGTGGTATATATCTGCAAACATTTAAAATGGTATAATATCATATAAAATGTCAAAATTA
GCACAGTCCCTGGATCTCAAAGAATAGGTAATATTGACTTGGATGTTCTTTATGCTCTCTGAAGAAAGGTCTAGGGAAAGTTCTTGTTTG
CTTGATTGATCAAGAGTGCCACGGAAGAATGTGAGCGCTGTGGAGGGTGGAGGAGGGTGTCACTTCAGATGGGGCAGGCACAGGGGGAGA
AAAGAAGAGAAAAACACACCTGTGTGCAAAATGAGCTATTTGGTTTCAGTGCGGCCTGACCGATGGGGAGGACCCATGAGCAGAGAGAGT
TCTAGGTCAACATTGTAACTCCATTGTCCTCCTTCACCCATAAGTCAGTCCTCCTTCCTCATTACAGTGAAACCAACAATATGCAGAGGT
TGGGGAGAGATGCCTGTTCTTCCCCCAGCTTCATATAATTGTCAAAGTTCCAAAAATGAATTATCTGAACTGCTTAAAACTGGAAATTAA
AATCTAGACAAGAATATGTCTTTCAAGAGCTTTTTATGTTTTGAAAGTTCATAAACCTAAGATTGGCTCCATCTGAGATAAATTTTCTTT
TCTTTTTTTTTTTGAGACGGAGTCTCGTTCTGTCTCCCAGGCTGGAGTGCAGTGGCATGATCTCGGCTCACTGCAACCTCCACCTCCTAG
GTTCAAGTGATTCTCCTGAGTAGCTGGGGTTATAGCTACCCACCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGGCAGGTTTTCA
CCATGTTGGCTAGGCTGGTCTTGAACTCCCGACCTCAAGTGATCCACCTGCCTTGGCCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCC
CCGTGCCTGGCCCACAATAAATTTTCATTTCAGAGAAGGAAAAAAATCTCTTGAACGTCCAGAAATGATTTCTGGAATCAGAATTTCAAT
ATGTAATACCCTCAGGTAGGCAATCTTGAACCCTCTATGCAGTGAGAGCATTATTAATATGAGATGTTGAATGATGCCTTTACAGACTTC
AGCAGCAAAGCCATTTGGTTGAGGTTTTCTGTGTTAATGTGAAAAGCTAAGCCACTGAGATTTGCAGGGGAGCTTCTGAGCCACCCTGCT
TGTTGGTTATATGAGGATGTAAAATAGGTGGAATTAAAATGTGAGCAGGAAAGGCAAGGCATGTGTGCATTTTCACTCATTTTGGTCAAG
GTTAAACTGACATGTATAGCACTGAGGTCTGTAGGGTTCTTAATATCTTTTGAGTCTTGCTGTGAAATGAAAGTGTGGGAGGTTTCCTTT
GTCCATTAGCAGCCCCAAGAACCAGAACCCTTTTGCTGCTTTTCTTACATACCTAACAGCTCTCCAGTCATGATGACCAAGGTTGTTCTT
CAATCAAATGTGTTTGTGGGATTTTCAGTCCGCAAATGAAGTGCTCTCTAATGAATGGGACACCATGATAAATATGTATTTATATTTAGA
TGCCAAAGTATGGCAAATTATTTCCAAATGATAACTACAAATGGGAATTTTCGATATTCTACCTTTTTTATAGAACCAGCTCACTTTTCA
TTTCTTTTTCATTTTGAATTAAGAAAATTGTTGAGGATGTGGTGGGTTCCAGTGTGTGGAATGGAAAGGAAACTGCAGAATAGTGTCTGC
TCCCCATTCAGAGGGACTGCTTCCTGTGCCCCCCAGACCCGGGGCTTCGACAGCTTCTCCACATTCCACACAGATGCCTAGGAGCAGCGA
GTTGGTATATGAAAAGTCTCCCACCTTTTCTCCTAAAACTTCTCTCCTTTCTCTCCATAAAAAGAAAAGGAAAGGAACAAAAGAAAAACA
TTCAGTTTTTCTTTTTCTGAAAAAGGTAAGTCCTTTCCTGAAGTCATCAAATGAAACATTATCTGGAAATTAGTTTCTAATGTTGTATAT
GAAGAAATACTTAAATATAAGTTCCTGCAGTATTTATTAGATAGTTGTAACTGTAAACTCACCTCCCTAGTAGATAAGAGTTTCAGGTTA
AATACTGGAACATATATAGGCAGTCAAAAATACTACTTTAAATGTCATTCACCTATTTTAAAGCCATGTTTTAGCACTTTTTAGGCCAAA
GAAGGTCTGATAGTGCCTGTTTTTATGTTCTGTACTCTCACAAACTTTGTTACTCAAAATTATTGCATGGCAGGAGAGATTGGATTATTT
ATTTCTTATATTTTTATAAGTAAAAAAATCTTTCTAAACAACAAATACCTAACATTATTACTGATTGTTTTCCTAATTTATCCTCCTAAG
TTGAATGGTAACAAAGCTTTTCCAGCTGAATGAATGCACTTAGCTGATAAACCAGAATTTGTTCTTTTTTTTCCTTCTTTTTTTTTTGAG
ACAGGTTCTCACTCTGTCACCGAGGTTGGAGTGCAGTGGTATGATCATAGCTGACTGCAGCCTCAACCTTCTGGGCTCAAATGATCCTTT
CACCTCAGCCTCCTGAGTAGCTGGGACCACAGGTGTGTGCCACCACACCTGGCTAATTTTTATGGATTTTTTTTTCTTTTTTTTTTTTCG
CCATGTTGCCCAGGCTGGTCTTGAACTCTTGGCACTCAAGCAGTCCTTCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGATGTGAGCC
ACTGCACCTGGCCCCAGAAATTATGCTTAAAAAAAAAATTAAGCTGTGTGGAATCTGGACAAGGCTATGTTTCTCCTAGAAACAGGTTTT
GCTGTAAATGGTTTTGATGGGCGAAAGTGTGAGAAAAGGTTATAATAGATTCTTTTTTTTAATTTTGTGAGAAATTCCAGGTCTTCTTGC
TTAACTTATATGCATGTGGATATATTTGTTTTCAAAGCCATGGAAGAATCTCTGTTCATATATTTTAATGCAAATTACCTTGTATGCTGC
TATGCAAATTCTATTAAAAGGCCTACCTGCTTAAGAATTAAACATTTTTGAAACTTTCAGGGAAGACCTGTAGACTCAAGCACTTTCTCT
GCTTTTTTGTATCTTATCTTGGACACTTATGCTGAATTATGTTCTTATTATTTTCACTGGTTATAAGCTATTCCTTGTACATAATATTTA
AACTATCCAAATATCCAGCATACATTTCCATGTGGCTGCCATCGGCTGTTGATGCCATGAATGAAATGGCTGGTTAGAAAGCCAAAGGTC
TTCTTTTTTCAATTCCTAATGAATAAGTAAAATGCCAGATCTCTTTGGTCTCAAAGCAAATTGCTCTGATCAGATCAAATATCTATGTAA
TGAAAAGAGACTTACTTAAATTTGGGATTCTGCTTAAACTTTAAGTTGAATTTGACTGTAGTCATTCATTCTTTTTATATATCTCTGTCA
GGTATGACATTAATTACCAGGTGGTATTATACTCTACTTTGAGTTTGGACATCACTTTCAGTTAAATTTCTGTTGTTATTGTGGCTTTTT
TTTTTTTTTAACCCCACTGAAGATGGAAGTAGAGCAGTCTGCCATCTCCTGCTGTTCTTTCTCTGTGCCCCCTAATTGCTTGGTAATCTA
AAATTATTCTGACTTTCCACATACTGTCTTTAAAAACCAATTGTAGCAATCTGCCCGCCTCCACCCTTTAAGCTAAATCTTTCACTGTGC
TGGATACATAGACACTCGATAAATGTGTGATGATAGTTCTAAAATAATTATGCTATATATCAGGGTTCTGTATTTTTGAGCAATATCATT
ATTCCTATGCTGTGATGTTAAATGGAATTTATTTTACACTAGTAATAGACTGCTTAAGTGGCTGATTTGAAACCTTTCTCTAAAAAAACA
AAAACATCTGGCAGATGAGTGACACAAATTCATTCTCTTAAAGGATAGAATTTCAAGTTAAGGATAAGGCACAATAAATAGGCACATAGA
GGACATCTGTTTTTGTTTTTGGTTTTGGTTTTGTTTTTTTTTGTCTCTCTGACTAGCTAAACTGCCAACTAGAAGAATGGTTGTTATGTA
GTAACTCAGAAGAATCTTTTAATAAGTTTCTTCTTTTGTTTCAAAACAAACTTGAGCTTCATTTCTTGCCACCTCTATTCTTTCTTCCCA
CGTTGGGTGACTGAACTGATGCTTATTCTAGTTTTAGAAGAGGATCCACATTTAATGTAAGGCATAAATATGCCTTTTGCAAATTATTGC
TTGTTCTCCAGTGAACATTTGATCATATTCAACAGAAATCCACCATATAAACCATAATCCTTGAATTGCCCCTTTTAAAATAGATTGGTT
AAAACCAAAAACCTATAAGAGAGAAATGATATTTCATTGTATTGTAGGTTTGGGAATCCTGGTTAGATTTATAATTTCTGGCCGGGTGCG
GTGGCTCATGCCTGTATTCCCAGTACTTTGGGAGCCCAAGGTGGGTGGATCACCTGAGGTAAGGAGTTTGAGACCAGCCTGGCCAACATG
GTGAAACCCCATCTCTACTAAAAATACAAAAAGTTAGCTGGGCATGGTGGTGCGCGCCTGTGGTCCCAGCTACTCGGGAGGCTGAGGTGG
GAGAATCCCTTGAACCCAGGAGGCAGAAGTTGCAGTGAGCTGAGATCATGCCATTGCACTCCAGCCTGGGCAACAGAGCGAGACTTCATC
TCCAAAAAAAGAAAAAGAAGAAAAAGATTTATAATTTCTGAGTCCCCTAAGTCCCTTTCTCAGTTTGCAATAATCTTACGTCCATGCTAT
TGACACTAATTTTGAAACTGGAAAGCTAATTAATGACATATTCATGTGTTCTTTCATCTAATAAACATTTATTAATGTATAGTTCTACAC
CAGGCATTCTGAAGGGTCCAAAAGAAAGTTCCTGCCCTCTAGTAGCACATAATCCGTTATTTCTCAGCACACCATGCCATCTGTTTATCA
TTCAGCAGTTAAGTAATTCATCACTTCATATTTTTACCAAAGTATATTTACAAGTCTGTTTATCTGGATCTGGCAAACTGGAAAATGTTT
GAAGGGATACTCAGGCTTTGATCCATGCCAACATGAAAGGACTCCAAGCACATTTAAGTAGGCTGGTCTTTTCATCATGCATGATTTTTT
TTTTAGTGCAAATTTAGACTTTAGTTTGGGAAAGAGAACAGTATACAGTATCCTTTGTAAGATAAATCACAACAACAAAAATTAAGTTTT
ATTGCACAAAGTAGATAAATGAGAAAGTCTTTCTTAAAAAATGCTTCTTTAACTGTAACAGCAAAACTAAATGCATATTTTATCAACCCC
TTATTTCTAATTGCTGTATTCATTTCCACCCTTAAACTATTTAAGCATTTCATCTGCTGAAAGTCCTTATATACATGGTAGACGGAATAT
TTCTCCATTAATGATAGATCAAAATGAAGATATTTAAAAATTAACAAAATCAGGCCAAGGCAGGAGGATCACTTTAGCCCAGGAGGTCCA
GACCAGCCTGGGCAACACAGCGGGACCCCGACTCCATTTAAAAAATTAAAAAAAAAAAAAAAACTTTTAACATTTAAAAAATAAAAATTA
ACAAAATTTCACTTATTCCAGGACACGCTGGCATTTGGACTCAATGAAAAGGGCACCTAAAGAAAATAAGGCTGACTGAATGTTTTCCAT
AATTTTCACACAATAACAGTCCCTTTCTATCCAGCTTGCCTTCCATTTATCTCTAGGGTTAGCTTTTCAGGCAACATCCTTGGTCATTGC
CCAGAAAGTACCTGAGCTATCAGTGATTGGAATGGCACAGGAAACCGAATCACATGGGTGCCCTCCCCTTGGTTTTCAAGTATCTTGGAG
TTGTGCACAAAAATTAGGTCATGCCTTCAGTGTCTTGTTCTTTAAACCTACCCTTTGACAATCAGGTGCTAATGATTGTATACTATTAAA
ACCAGCACATAAGTATTGTAAATGTGTGTTCCTCCTAGGTTGGAAGAAATGTCTTTCCTTCTATCTGGGTCCTGTTAAAGCGGGTGTCAG
TTGTGTCTTTTCACCTCGATTTGTGAATTAATAGAATTGGGGGGAGAGGAAATGATGATGTCAATTAAGTTTCAGGTTTGGCATGATCAT
CATTCTCGATGATATTCTCACTTTGTCGCAAATCTGCCCTTATCGTAAGAACAAGTTTCAGAATTTTCCCTCCACTATACGACTCCAGTA
TTATGTTTACAATCCATTGGATGAGTGCAGCATTATAAGACCTTGGTGCCCAGAAAAATCTGTCCTTTTTGGTACCAAACCTGAGGTCTT
TTGGAAGATAATGTAGAAAACCACTACCTATTGAAGGCCTGTTTTGGCTAATCTGTGCAAACTCTGATGATACCTGCTTATGTGGATTCT
TTTCCACACTGCTTTCATTTTTAAGTATAAAGACTTAGAAAACTAGAATAATGCTTTTACAAATAATTAAAAGTATGTGATGTTCTGGGT
TTTTTCCTTCTTTTTAGAACCCTGTATTTAAACAAGCCTTCTTTTTAAGTCTTGTTTGAAATTTAAGTCTCAGATCTTCTGGATACCAAA
TCAAAAACCCAACGCGTAAAACAGGGCAGTATTTGTGTTCCTAATTTTAAAAAGCTTTATGTATACTCTATAAATATAGATGCATAAACA
ACACTTCCCCTTGAGTAGCACATCAACATACAGCATTGTACATTACAATGAAAATGTGTAACTTAAGGGTATTATATATATAAATACATA

>20923_20923_1_CYB5B-SNTB2_CYB5B_chr16_69493024_ENST00000307892_SNTB2_chr16_69293953_ENST00000336278_length(amino acids)=396AA_BP=120
MSGSMATAEASGSDGKGQEVETSVTYYRLEEVAKRNSLKELWLVIHGRVYDVTRFLNEHPGGEEVLLEQAGVDASESFEDVGHSSDAREM
LKQYYIGDIHPSDLKPESGSKDPSKNDTCKRLIELHSPDSRNTLILRCKDTATAHSWFVAIHTNIMALLPQVLAELNAMLGATSTAGGSK
EVKHIAWLAEQAKLDGGRQQWRPVLMAVTEKDLLLYDCMPWTRDAWASPCHSYPLVATRLVHSGSGCRSPSLGSDLTFATRTGSRQGIEM
HLFRVETHRDLSSWTRILVQGCHAAAELIKEVSLGCMLNGQEVRLTIHYENGFTISRENGGSSSILYRYPFERLKMSADDGIRNLYLDFG

--------------------------------------------------------------
>20923_20923_2_CYB5B-SNTB2_CYB5B_chr16_69493024_ENST00000512062_SNTB2_chr16_69293953_ENST00000336278_length(transcript)=9478nt_BP=521nt
GAAAAGAAAACGAACCAGGAACTATTCGGAAGTGTGATTGGCTGTTGCTAGGAACCGTCTCAAGGCCTTATGGGCCCTGGTTACGGAAGC
CGAGGAAGGCTGAGCGCGGGCTCTCAAGGAAAGTAGTCGCGGAATCTCAGTTAGCGGTGGAGAGGCAGTATGTCCGGTTCAATGGCGACT
GCGGAAGCTAGCGGCAGCGATGGGAAAGGGCAGGAAGTCGAGACCTCAGTCACCTATTACCGGTTGGAGGAGGTGGCAAAGCGCAACTCC
TTGAAGGAACTGTGGCTTGTGATCCATGGGCGAGTCTACGATGTCACCCGCTTCCTCAACGAGCACCCTGGAGGAGAAGAGGTTCTGCTG
GAACAAGCTGGTGTAGATGCAAGTGAAAGCTTTGAAGATGTAGGACACTCTTCTGATGCCAGAGAAATGCTAAAGCAGTACTACATTGGT
GATATCCATCCGAGTGACCTTAAACCTGAAAGTGGTAGCAAGGACCCTTCAAAAAATGATACATGCAAAAGATTGATAGAGCTACATTCT
CCTGATAGCAGGAACACGTTGATCCTACGCTGCAAAGATACAGCCACAGCACACTCCTGGTTCGTAGCTATCCACACCAACATAATGGCT
CTCCTCCCACAGGTGTTGGCTGAACTCAACGCCATGCTTGGGGCAACCAGTACAGCAGGAGGCAGTAAAGAGGTGAAGCATATTGCCTGG
CTGGCAGAACAGGCAAAACTAGATGGTGGAAGACAGCAATGGAGACCTGTCCTCATGGCTGTGACTGAGAAGGATTTGCTGCTCTATGAC
TGTATGCCGTGGACAAGAGATGCCTGGGCGTCACCATGCCACAGCTACCCACTTGTTGCCACCAGGTTGGTTCATTCTGGCTCCGGATGT
CGATCCCCCTCCCTTGGATCTGACCTTACATTTGCTACCAGGACAGGCTCTCGACAGGGCATTGAGATGCATCTCTTCAGGGTGGAGACA
CATCGGGATCTGTCATCCTGGACCAGGATACTTGTTCAGGGTTGCCATGCTGCTGCTGAGCTGATCAAGGAAGTCTCTCTAGGCTGCATG
TTAAATGGCCAAGAGGTGAGGCTTACTATTCACTATGAAAATGGGTTCACCATCTCAAGGGAAAATGGAGGCTCCAGCAGCATATTGTAC
CGCTACCCCTTTGAAAGGCTGAAGATGTCTGCTGATGATGGCATCCGAAATCTATACTTGGATTTTGGTGGTCCCGAGGGAGAACTGACC
ATGGACCTGCACTCTTGTCCGAAGCCGATTGTATTTGTGTTGCACACGTTTTTATCGGCCAAAGTCACTCGTATGGGACTGCTTGTATGA
GCAACAAAAAATCAGAAAAGAGCCTTGACTGTCACAAGAAATATTTCCACCTCAAAAAAAAAAAAGCACAAAAAGAAACTCTTTGCTCTC
CTTCAGCACAGTGCCTTCCCAAGGACCTGCAAATAACTGCTGAACCATAACCGTGTTTAAAGAAGAGCCTACCTTTCACAGTCTACCTTG
GCCAGATATTCTAGCACTCTAAAAGGCTCCAAAATGAAGCTGTTGATTTATTCTCATTTCAAAATATGGTTTATGAGTAATTAGGTTTAT
TTCTACTGCTAAAAAGAATGGCTCATTGTTTTCTTTTTTTTTCATTGTTTTCATTTTTAGACATAATCAAATACCCAAGCATTGTTTTCT
TTTTCTTCTCCCTGTAGGATTTGTGTTGTGCTTAGCCTTGATCTCTTGTTCAGAACAATTGTCCCTTCCCAGGTGCTAGCTTGCAGCAGC
CTGTTGCTTCCTGAGCATTCCAGATAGGTCGTATGTCTTGGAATTTACTGTCCTCACTAGCTCCTTCCACCATAGGAAGTCCTTGAATTG
TATCACCAAAGGGTTGTTCCATTTGCCCTGGATCTCCCTCTATCTCAGCCTGGCCATCACTTCCCACCTTATCCCAAGCTTTGCCACTGT
CTCTAGGACTTAGAACTTGTAAATTTGATTTGCCTTGCCTTCTACTTCCTTTCTAGTGGTGACTGAGTTGAAAAGCAAGTTGGAAGCCAC
TGCTTTTAAAGAAAAGTTTTGCTTGGTTTAGGTTTTTCCAATTTTATTTTTGTTAGGAGCCAGGGGATAAGATTTATTTTAAATGAAAAT
CCTCTTCCTAGGTTAAGCCATTTTTTTTATTGCTTACCAAATGTGCCTTTGGTTAGGGTTAGTGGAGCTTTATTAGTCACTATTTGAATA
ACTGGAAATCACTGCCATTTCCAGGAGATCACCTATCCTAGTTTTGAGGAATAGTCATTGAGGTGGGTTTCCTTAATGGCATCTCTTCTA
GTAGGCAGATCTGTTTGAACAAGATAAATCCTAAAGAGCCAGCCTGCTTGAGGAGTAGACTTGGTGGGTGAAGCCAGCAATTCCGCACAA
ACGTCATGTTGAATTGTTTTGGGCTGCCCAAAAACAACAGGATGCAGCATCCTGGCTGTGGCCTGGCCCTTTGTGGCAGCAGTGGCATGG
ACAAGCAACTGCTAATTCGAGACTTACTATTGGCTTCACAGCACACCCTACAGTGAGCAGGGTGATGAGACCGTGGAACAGCTACCTGCT
TTTGGTTAAGATTGCCAGATATCATTAGGACACAGTAGCAGCAAGAATGCTGATTTTGTAGTGTTAGAAAATGAACTCAGCTTGTTTTTC
CTAATTTTGAAGGTGGTATATATCTGCAAACATTTAAAATGGTATAATATCATATAAAATGTCAAAATTAGCACAGTCCCTGGATCTCAA
AGAATAGGTAATATTGACTTGGATGTTCTTTATGCTCTCTGAAGAAAGGTCTAGGGAAAGTTCTTGTTTGCTTGATTGATCAAGAGTGCC
ACGGAAGAATGTGAGCGCTGTGGAGGGTGGAGGAGGGTGTCACTTCAGATGGGGCAGGCACAGGGGGAGAAAAGAAGAGAAAAACACACC
TGTGTGCAAAATGAGCTATTTGGTTTCAGTGCGGCCTGACCGATGGGGAGGACCCATGAGCAGAGAGAGTTCTAGGTCAACATTGTAACT
CCATTGTCCTCCTTCACCCATAAGTCAGTCCTCCTTCCTCATTACAGTGAAACCAACAATATGCAGAGGTTGGGGAGAGATGCCTGTTCT
TCCCCCAGCTTCATATAATTGTCAAAGTTCCAAAAATGAATTATCTGAACTGCTTAAAACTGGAAATTAAAATCTAGACAAGAATATGTC
TTTCAAGAGCTTTTTATGTTTTGAAAGTTCATAAACCTAAGATTGGCTCCATCTGAGATAAATTTTCTTTTCTTTTTTTTTTTGAGACGG
AGTCTCGTTCTGTCTCCCAGGCTGGAGTGCAGTGGCATGATCTCGGCTCACTGCAACCTCCACCTCCTAGGTTCAAGTGATTCTCCTGAG
TAGCTGGGGTTATAGCTACCCACCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGGCAGGTTTTCACCATGTTGGCTAGGCTGGTC
TTGAACTCCCGACCTCAAGTGATCCACCTGCCTTGGCCTCCCAAAGTGCTGGGATTATAGGTGTGAGCCCCCGTGCCTGGCCCACAATAA
ATTTTCATTTCAGAGAAGGAAAAAAATCTCTTGAACGTCCAGAAATGATTTCTGGAATCAGAATTTCAATATGTAATACCCTCAGGTAGG
CAATCTTGAACCCTCTATGCAGTGAGAGCATTATTAATATGAGATGTTGAATGATGCCTTTACAGACTTCAGCAGCAAAGCCATTTGGTT
GAGGTTTTCTGTGTTAATGTGAAAAGCTAAGCCACTGAGATTTGCAGGGGAGCTTCTGAGCCACCCTGCTTGTTGGTTATATGAGGATGT
AAAATAGGTGGAATTAAAATGTGAGCAGGAAAGGCAAGGCATGTGTGCATTTTCACTCATTTTGGTCAAGGTTAAACTGACATGTATAGC
ACTGAGGTCTGTAGGGTTCTTAATATCTTTTGAGTCTTGCTGTGAAATGAAAGTGTGGGAGGTTTCCTTTGTCCATTAGCAGCCCCAAGA
ACCAGAACCCTTTTGCTGCTTTTCTTACATACCTAACAGCTCTCCAGTCATGATGACCAAGGTTGTTCTTCAATCAAATGTGTTTGTGGG
ATTTTCAGTCCGCAAATGAAGTGCTCTCTAATGAATGGGACACCATGATAAATATGTATTTATATTTAGATGCCAAAGTATGGCAAATTA
TTTCCAAATGATAACTACAAATGGGAATTTTCGATATTCTACCTTTTTTATAGAACCAGCTCACTTTTCATTTCTTTTTCATTTTGAATT
AAGAAAATTGTTGAGGATGTGGTGGGTTCCAGTGTGTGGAATGGAAAGGAAACTGCAGAATAGTGTCTGCTCCCCATTCAGAGGGACTGC
TTCCTGTGCCCCCCAGACCCGGGGCTTCGACAGCTTCTCCACATTCCACACAGATGCCTAGGAGCAGCGAGTTGGTATATGAAAAGTCTC
CCACCTTTTCTCCTAAAACTTCTCTCCTTTCTCTCCATAAAAAGAAAAGGAAAGGAACAAAAGAAAAACATTCAGTTTTTCTTTTTCTGA
AAAAGGTAAGTCCTTTCCTGAAGTCATCAAATGAAACATTATCTGGAAATTAGTTTCTAATGTTGTATATGAAGAAATACTTAAATATAA
GTTCCTGCAGTATTTATTAGATAGTTGTAACTGTAAACTCACCTCCCTAGTAGATAAGAGTTTCAGGTTAAATACTGGAACATATATAGG
CAGTCAAAAATACTACTTTAAATGTCATTCACCTATTTTAAAGCCATGTTTTAGCACTTTTTAGGCCAAAGAAGGTCTGATAGTGCCTGT
TTTTATGTTCTGTACTCTCACAAACTTTGTTACTCAAAATTATTGCATGGCAGGAGAGATTGGATTATTTATTTCTTATATTTTTATAAG
TAAAAAAATCTTTCTAAACAACAAATACCTAACATTATTACTGATTGTTTTCCTAATTTATCCTCCTAAGTTGAATGGTAACAAAGCTTT
TCCAGCTGAATGAATGCACTTAGCTGATAAACCAGAATTTGTTCTTTTTTTTCCTTCTTTTTTTTTTGAGACAGGTTCTCACTCTGTCAC
CGAGGTTGGAGTGCAGTGGTATGATCATAGCTGACTGCAGCCTCAACCTTCTGGGCTCAAATGATCCTTTCACCTCAGCCTCCTGAGTAG
CTGGGACCACAGGTGTGTGCCACCACACCTGGCTAATTTTTATGGATTTTTTTTTCTTTTTTTTTTTTCGCCATGTTGCCCAGGCTGGTC
TTGAACTCTTGGCACTCAAGCAGTCCTTCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGATGTGAGCCACTGCACCTGGCCCCAGAAA
TTATGCTTAAAAAAAAAATTAAGCTGTGTGGAATCTGGACAAGGCTATGTTTCTCCTAGAAACAGGTTTTGCTGTAAATGGTTTTGATGG
GCGAAAGTGTGAGAAAAGGTTATAATAGATTCTTTTTTTTAATTTTGTGAGAAATTCCAGGTCTTCTTGCTTAACTTATATGCATGTGGA
TATATTTGTTTTCAAAGCCATGGAAGAATCTCTGTTCATATATTTTAATGCAAATTACCTTGTATGCTGCTATGCAAATTCTATTAAAAG
GCCTACCTGCTTAAGAATTAAACATTTTTGAAACTTTCAGGGAAGACCTGTAGACTCAAGCACTTTCTCTGCTTTTTTGTATCTTATCTT
GGACACTTATGCTGAATTATGTTCTTATTATTTTCACTGGTTATAAGCTATTCCTTGTACATAATATTTAAACTATCCAAATATCCAGCA
TACATTTCCATGTGGCTGCCATCGGCTGTTGATGCCATGAATGAAATGGCTGGTTAGAAAGCCAAAGGTCTTCTTTTTTCAATTCCTAAT
GAATAAGTAAAATGCCAGATCTCTTTGGTCTCAAAGCAAATTGCTCTGATCAGATCAAATATCTATGTAATGAAAAGAGACTTACTTAAA
TTTGGGATTCTGCTTAAACTTTAAGTTGAATTTGACTGTAGTCATTCATTCTTTTTATATATCTCTGTCAGGTATGACATTAATTACCAG
GTGGTATTATACTCTACTTTGAGTTTGGACATCACTTTCAGTTAAATTTCTGTTGTTATTGTGGCTTTTTTTTTTTTTTAACCCCACTGA
AGATGGAAGTAGAGCAGTCTGCCATCTCCTGCTGTTCTTTCTCTGTGCCCCCTAATTGCTTGGTAATCTAAAATTATTCTGACTTTCCAC
ATACTGTCTTTAAAAACCAATTGTAGCAATCTGCCCGCCTCCACCCTTTAAGCTAAATCTTTCACTGTGCTGGATACATAGACACTCGAT
AAATGTGTGATGATAGTTCTAAAATAATTATGCTATATATCAGGGTTCTGTATTTTTGAGCAATATCATTATTCCTATGCTGTGATGTTA
AATGGAATTTATTTTACACTAGTAATAGACTGCTTAAGTGGCTGATTTGAAACCTTTCTCTAAAAAAACAAAAACATCTGGCAGATGAGT
GACACAAATTCATTCTCTTAAAGGATAGAATTTCAAGTTAAGGATAAGGCACAATAAATAGGCACATAGAGGACATCTGTTTTTGTTTTT
GGTTTTGGTTTTGTTTTTTTTTGTCTCTCTGACTAGCTAAACTGCCAACTAGAAGAATGGTTGTTATGTAGTAACTCAGAAGAATCTTTT
AATAAGTTTCTTCTTTTGTTTCAAAACAAACTTGAGCTTCATTTCTTGCCACCTCTATTCTTTCTTCCCACGTTGGGTGACTGAACTGAT
GCTTATTCTAGTTTTAGAAGAGGATCCACATTTAATGTAAGGCATAAATATGCCTTTTGCAAATTATTGCTTGTTCTCCAGTGAACATTT
GATCATATTCAACAGAAATCCACCATATAAACCATAATCCTTGAATTGCCCCTTTTAAAATAGATTGGTTAAAACCAAAAACCTATAAGA
GAGAAATGATATTTCATTGTATTGTAGGTTTGGGAATCCTGGTTAGATTTATAATTTCTGGCCGGGTGCGGTGGCTCATGCCTGTATTCC
CAGTACTTTGGGAGCCCAAGGTGGGTGGATCACCTGAGGTAAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTA
AAAATACAAAAAGTTAGCTGGGCATGGTGGTGCGCGCCTGTGGTCCCAGCTACTCGGGAGGCTGAGGTGGGAGAATCCCTTGAACCCAGG
AGGCAGAAGTTGCAGTGAGCTGAGATCATGCCATTGCACTCCAGCCTGGGCAACAGAGCGAGACTTCATCTCCAAAAAAAGAAAAAGAAG
AAAAAGATTTATAATTTCTGAGTCCCCTAAGTCCCTTTCTCAGTTTGCAATAATCTTACGTCCATGCTATTGACACTAATTTTGAAACTG
GAAAGCTAATTAATGACATATTCATGTGTTCTTTCATCTAATAAACATTTATTAATGTATAGTTCTACACCAGGCATTCTGAAGGGTCCA
AAAGAAAGTTCCTGCCCTCTAGTAGCACATAATCCGTTATTTCTCAGCACACCATGCCATCTGTTTATCATTCAGCAGTTAAGTAATTCA
TCACTTCATATTTTTACCAAAGTATATTTACAAGTCTGTTTATCTGGATCTGGCAAACTGGAAAATGTTTGAAGGGATACTCAGGCTTTG
ATCCATGCCAACATGAAAGGACTCCAAGCACATTTAAGTAGGCTGGTCTTTTCATCATGCATGATTTTTTTTTTAGTGCAAATTTAGACT
TTAGTTTGGGAAAGAGAACAGTATACAGTATCCTTTGTAAGATAAATCACAACAACAAAAATTAAGTTTTATTGCACAAAGTAGATAAAT
GAGAAAGTCTTTCTTAAAAAATGCTTCTTTAACTGTAACAGCAAAACTAAATGCATATTTTATCAACCCCTTATTTCTAATTGCTGTATT
CATTTCCACCCTTAAACTATTTAAGCATTTCATCTGCTGAAAGTCCTTATATACATGGTAGACGGAATATTTCTCCATTAATGATAGATC
AAAATGAAGATATTTAAAAATTAACAAAATCAGGCCAAGGCAGGAGGATCACTTTAGCCCAGGAGGTCCAGACCAGCCTGGGCAACACAG
CGGGACCCCGACTCCATTTAAAAAATTAAAAAAAAAAAAAAAACTTTTAACATTTAAAAAATAAAAATTAACAAAATTTCACTTATTCCA
GGACACGCTGGCATTTGGACTCAATGAAAAGGGCACCTAAAGAAAATAAGGCTGACTGAATGTTTTCCATAATTTTCACACAATAACAGT
CCCTTTCTATCCAGCTTGCCTTCCATTTATCTCTAGGGTTAGCTTTTCAGGCAACATCCTTGGTCATTGCCCAGAAAGTACCTGAGCTAT
CAGTGATTGGAATGGCACAGGAAACCGAATCACATGGGTGCCCTCCCCTTGGTTTTCAAGTATCTTGGAGTTGTGCACAAAAATTAGGTC
ATGCCTTCAGTGTCTTGTTCTTTAAACCTACCCTTTGACAATCAGGTGCTAATGATTGTATACTATTAAAACCAGCACATAAGTATTGTA
AATGTGTGTTCCTCCTAGGTTGGAAGAAATGTCTTTCCTTCTATCTGGGTCCTGTTAAAGCGGGTGTCAGTTGTGTCTTTTCACCTCGAT
TTGTGAATTAATAGAATTGGGGGGAGAGGAAATGATGATGTCAATTAAGTTTCAGGTTTGGCATGATCATCATTCTCGATGATATTCTCA
CTTTGTCGCAAATCTGCCCTTATCGTAAGAACAAGTTTCAGAATTTTCCCTCCACTATACGACTCCAGTATTATGTTTACAATCCATTGG
ATGAGTGCAGCATTATAAGACCTTGGTGCCCAGAAAAATCTGTCCTTTTTGGTACCAAACCTGAGGTCTTTTGGAAGATAATGTAGAAAA
CCACTACCTATTGAAGGCCTGTTTTGGCTAATCTGTGCAAACTCTGATGATACCTGCTTATGTGGATTCTTTTCCACACTGCTTTCATTT
TTAAGTATAAAGACTTAGAAAACTAGAATAATGCTTTTACAAATAATTAAAAGTATGTGATGTTCTGGGTTTTTTCCTTCTTTTTAGAAC
CCTGTATTTAAACAAGCCTTCTTTTTAAGTCTTGTTTGAAATTTAAGTCTCAGATCTTCTGGATACCAAATCAAAAACCCAACGCGTAAA
ACAGGGCAGTATTTGTGTTCCTAATTTTAAAAAGCTTTATGTATACTCTATAAATATAGATGCATAAACAACACTTCCCCTTGAGTAGCA
CATCAACATACAGCATTGTACATTACAATGAAAATGTGTAACTTAAGGGTATTATATATATAAATACATATATACCTTTGTAACCTTTAT

>20923_20923_2_CYB5B-SNTB2_CYB5B_chr16_69493024_ENST00000512062_SNTB2_chr16_69293953_ENST00000336278_length(amino acids)=396AA_BP=120
MSGSMATAEASGSDGKGQEVETSVTYYRLEEVAKRNSLKELWLVIHGRVYDVTRFLNEHPGGEEVLLEQAGVDASESFEDVGHSSDAREM
LKQYYIGDIHPSDLKPESGSKDPSKNDTCKRLIELHSPDSRNTLILRCKDTATAHSWFVAIHTNIMALLPQVLAELNAMLGATSTAGGSK
EVKHIAWLAEQAKLDGGRQQWRPVLMAVTEKDLLLYDCMPWTRDAWASPCHSYPLVATRLVHSGSGCRSPSLGSDLTFATRTGSRQGIEM
HLFRVETHRDLSSWTRILVQGCHAAAELIKEVSLGCMLNGQEVRLTIHYENGFTISRENGGSSSILYRYPFERLKMSADDGIRNLYLDFG

--------------------------------------------------------------
>20923_20923_3_CYB5B-SNTB2_CYB5B_chr16_69493024_ENST00000561792_SNTB2_chr16_69293953_ENST00000336278_length(transcript)=9323nt_BP=366nt
CAGTATGTCCGGTTCAATGGCGACTGCGGAAGCTAGCGGCAGCGATGGGAAAGGGCAGGAAGTCGAGACCTCAGTCACCTATTACCGGTT
GGAGGAGGTGGCAAAGCGCAACTCCTTGAAGGAACTGTGGCTTGTGATCCATGGGCGAGTCTACGATGTCACCCGCTTCCTCAACGAGCA
CCCTGGAGGAGAAGAGGTTCTGCTGGAACAAGCTGGTGTAGATGCAAGTGAAAGCTTTGAAGATGTAGGACACTCTTCTGATGCCAGAGA
AATGCTAAAGCAGTACTACATTGGTGATATCCATCCGAGTGACCTTAAACCTGAAAGTGGTAGCAAGGACCCTTCAAAAAATGATACATG
CAAAAGATTGATAGAGCTACATTCTCCTGATAGCAGGAACACGTTGATCCTACGCTGCAAAGATACAGCCACAGCACACTCCTGGTTCGT
AGCTATCCACACCAACATAATGGCTCTCCTCCCACAGGTGTTGGCTGAACTCAACGCCATGCTTGGGGCAACCAGTACAGCAGGAGGCAG
TAAAGAGGTGAAGCATATTGCCTGGCTGGCAGAACAGGCAAAACTAGATGGTGGAAGACAGCAATGGAGACCTGTCCTCATGGCTGTGAC
TGAGAAGGATTTGCTGCTCTATGACTGTATGCCGTGGACAAGAGATGCCTGGGCGTCACCATGCCACAGCTACCCACTTGTTGCCACCAG
GTTGGTTCATTCTGGCTCCGGATGTCGATCCCCCTCCCTTGGATCTGACCTTACATTTGCTACCAGGACAGGCTCTCGACAGGGCATTGA
GATGCATCTCTTCAGGGTGGAGACACATCGGGATCTGTCATCCTGGACCAGGATACTTGTTCAGGGTTGCCATGCTGCTGCTGAGCTGAT
CAAGGAAGTCTCTCTAGGCTGCATGTTAAATGGCCAAGAGGTGAGGCTTACTATTCACTATGAAAATGGGTTCACCATCTCAAGGGAAAA
TGGAGGCTCCAGCAGCATATTGTACCGCTACCCCTTTGAAAGGCTGAAGATGTCTGCTGATGATGGCATCCGAAATCTATACTTGGATTT
TGGTGGTCCCGAGGGAGAACTGACCATGGACCTGCACTCTTGTCCGAAGCCGATTGTATTTGTGTTGCACACGTTTTTATCGGCCAAAGT
CACTCGTATGGGACTGCTTGTATGAGCAACAAAAAATCAGAAAAGAGCCTTGACTGTCACAAGAAATATTTCCACCTCAAAAAAAAAAAA
GCACAAAAAGAAACTCTTTGCTCTCCTTCAGCACAGTGCCTTCCCAAGGACCTGCAAATAACTGCTGAACCATAACCGTGTTTAAAGAAG
AGCCTACCTTTCACAGTCTACCTTGGCCAGATATTCTAGCACTCTAAAAGGCTCCAAAATGAAGCTGTTGATTTATTCTCATTTCAAAAT
ATGGTTTATGAGTAATTAGGTTTATTTCTACTGCTAAAAAGAATGGCTCATTGTTTTCTTTTTTTTTCATTGTTTTCATTTTTAGACATA
ATCAAATACCCAAGCATTGTTTTCTTTTTCTTCTCCCTGTAGGATTTGTGTTGTGCTTAGCCTTGATCTCTTGTTCAGAACAATTGTCCC
TTCCCAGGTGCTAGCTTGCAGCAGCCTGTTGCTTCCTGAGCATTCCAGATAGGTCGTATGTCTTGGAATTTACTGTCCTCACTAGCTCCT
TCCACCATAGGAAGTCCTTGAATTGTATCACCAAAGGGTTGTTCCATTTGCCCTGGATCTCCCTCTATCTCAGCCTGGCCATCACTTCCC
ACCTTATCCCAAGCTTTGCCACTGTCTCTAGGACTTAGAACTTGTAAATTTGATTTGCCTTGCCTTCTACTTCCTTTCTAGTGGTGACTG
AGTTGAAAAGCAAGTTGGAAGCCACTGCTTTTAAAGAAAAGTTTTGCTTGGTTTAGGTTTTTCCAATTTTATTTTTGTTAGGAGCCAGGG
GATAAGATTTATTTTAAATGAAAATCCTCTTCCTAGGTTAAGCCATTTTTTTTATTGCTTACCAAATGTGCCTTTGGTTAGGGTTAGTGG
AGCTTTATTAGTCACTATTTGAATAACTGGAAATCACTGCCATTTCCAGGAGATCACCTATCCTAGTTTTGAGGAATAGTCATTGAGGTG
GGTTTCCTTAATGGCATCTCTTCTAGTAGGCAGATCTGTTTGAACAAGATAAATCCTAAAGAGCCAGCCTGCTTGAGGAGTAGACTTGGT
GGGTGAAGCCAGCAATTCCGCACAAACGTCATGTTGAATTGTTTTGGGCTGCCCAAAAACAACAGGATGCAGCATCCTGGCTGTGGCCTG
GCCCTTTGTGGCAGCAGTGGCATGGACAAGCAACTGCTAATTCGAGACTTACTATTGGCTTCACAGCACACCCTACAGTGAGCAGGGTGA
TGAGACCGTGGAACAGCTACCTGCTTTTGGTTAAGATTGCCAGATATCATTAGGACACAGTAGCAGCAAGAATGCTGATTTTGTAGTGTT
AGAAAATGAACTCAGCTTGTTTTTCCTAATTTTGAAGGTGGTATATATCTGCAAACATTTAAAATGGTATAATATCATATAAAATGTCAA
AATTAGCACAGTCCCTGGATCTCAAAGAATAGGTAATATTGACTTGGATGTTCTTTATGCTCTCTGAAGAAAGGTCTAGGGAAAGTTCTT
GTTTGCTTGATTGATCAAGAGTGCCACGGAAGAATGTGAGCGCTGTGGAGGGTGGAGGAGGGTGTCACTTCAGATGGGGCAGGCACAGGG
GGAGAAAAGAAGAGAAAAACACACCTGTGTGCAAAATGAGCTATTTGGTTTCAGTGCGGCCTGACCGATGGGGAGGACCCATGAGCAGAG
AGAGTTCTAGGTCAACATTGTAACTCCATTGTCCTCCTTCACCCATAAGTCAGTCCTCCTTCCTCATTACAGTGAAACCAACAATATGCA
GAGGTTGGGGAGAGATGCCTGTTCTTCCCCCAGCTTCATATAATTGTCAAAGTTCCAAAAATGAATTATCTGAACTGCTTAAAACTGGAA
ATTAAAATCTAGACAAGAATATGTCTTTCAAGAGCTTTTTATGTTTTGAAAGTTCATAAACCTAAGATTGGCTCCATCTGAGATAAATTT
TCTTTTCTTTTTTTTTTTGAGACGGAGTCTCGTTCTGTCTCCCAGGCTGGAGTGCAGTGGCATGATCTCGGCTCACTGCAACCTCCACCT
CCTAGGTTCAAGTGATTCTCCTGAGTAGCTGGGGTTATAGCTACCCACCACCACACCCAGCTAATTTTTGTATTTTTAGTAGAGGCAGGT
TTTCACCATGTTGGCTAGGCTGGTCTTGAACTCCCGACCTCAAGTGATCCACCTGCCTTGGCCTCCCAAAGTGCTGGGATTATAGGTGTG
AGCCCCCGTGCCTGGCCCACAATAAATTTTCATTTCAGAGAAGGAAAAAAATCTCTTGAACGTCCAGAAATGATTTCTGGAATCAGAATT
TCAATATGTAATACCCTCAGGTAGGCAATCTTGAACCCTCTATGCAGTGAGAGCATTATTAATATGAGATGTTGAATGATGCCTTTACAG
ACTTCAGCAGCAAAGCCATTTGGTTGAGGTTTTCTGTGTTAATGTGAAAAGCTAAGCCACTGAGATTTGCAGGGGAGCTTCTGAGCCACC
CTGCTTGTTGGTTATATGAGGATGTAAAATAGGTGGAATTAAAATGTGAGCAGGAAAGGCAAGGCATGTGTGCATTTTCACTCATTTTGG
TCAAGGTTAAACTGACATGTATAGCACTGAGGTCTGTAGGGTTCTTAATATCTTTTGAGTCTTGCTGTGAAATGAAAGTGTGGGAGGTTT
CCTTTGTCCATTAGCAGCCCCAAGAACCAGAACCCTTTTGCTGCTTTTCTTACATACCTAACAGCTCTCCAGTCATGATGACCAAGGTTG
TTCTTCAATCAAATGTGTTTGTGGGATTTTCAGTCCGCAAATGAAGTGCTCTCTAATGAATGGGACACCATGATAAATATGTATTTATAT
TTAGATGCCAAAGTATGGCAAATTATTTCCAAATGATAACTACAAATGGGAATTTTCGATATTCTACCTTTTTTATAGAACCAGCTCACT
TTTCATTTCTTTTTCATTTTGAATTAAGAAAATTGTTGAGGATGTGGTGGGTTCCAGTGTGTGGAATGGAAAGGAAACTGCAGAATAGTG
TCTGCTCCCCATTCAGAGGGACTGCTTCCTGTGCCCCCCAGACCCGGGGCTTCGACAGCTTCTCCACATTCCACACAGATGCCTAGGAGC
AGCGAGTTGGTATATGAAAAGTCTCCCACCTTTTCTCCTAAAACTTCTCTCCTTTCTCTCCATAAAAAGAAAAGGAAAGGAACAAAAGAA
AAACATTCAGTTTTTCTTTTTCTGAAAAAGGTAAGTCCTTTCCTGAAGTCATCAAATGAAACATTATCTGGAAATTAGTTTCTAATGTTG
TATATGAAGAAATACTTAAATATAAGTTCCTGCAGTATTTATTAGATAGTTGTAACTGTAAACTCACCTCCCTAGTAGATAAGAGTTTCA
GGTTAAATACTGGAACATATATAGGCAGTCAAAAATACTACTTTAAATGTCATTCACCTATTTTAAAGCCATGTTTTAGCACTTTTTAGG
CCAAAGAAGGTCTGATAGTGCCTGTTTTTATGTTCTGTACTCTCACAAACTTTGTTACTCAAAATTATTGCATGGCAGGAGAGATTGGAT
TATTTATTTCTTATATTTTTATAAGTAAAAAAATCTTTCTAAACAACAAATACCTAACATTATTACTGATTGTTTTCCTAATTTATCCTC
CTAAGTTGAATGGTAACAAAGCTTTTCCAGCTGAATGAATGCACTTAGCTGATAAACCAGAATTTGTTCTTTTTTTTCCTTCTTTTTTTT
TTGAGACAGGTTCTCACTCTGTCACCGAGGTTGGAGTGCAGTGGTATGATCATAGCTGACTGCAGCCTCAACCTTCTGGGCTCAAATGAT
CCTTTCACCTCAGCCTCCTGAGTAGCTGGGACCACAGGTGTGTGCCACCACACCTGGCTAATTTTTATGGATTTTTTTTTCTTTTTTTTT
TTTCGCCATGTTGCCCAGGCTGGTCTTGAACTCTTGGCACTCAAGCAGTCCTTCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGATGT
GAGCCACTGCACCTGGCCCCAGAAATTATGCTTAAAAAAAAAATTAAGCTGTGTGGAATCTGGACAAGGCTATGTTTCTCCTAGAAACAG
GTTTTGCTGTAAATGGTTTTGATGGGCGAAAGTGTGAGAAAAGGTTATAATAGATTCTTTTTTTTAATTTTGTGAGAAATTCCAGGTCTT
CTTGCTTAACTTATATGCATGTGGATATATTTGTTTTCAAAGCCATGGAAGAATCTCTGTTCATATATTTTAATGCAAATTACCTTGTAT
GCTGCTATGCAAATTCTATTAAAAGGCCTACCTGCTTAAGAATTAAACATTTTTGAAACTTTCAGGGAAGACCTGTAGACTCAAGCACTT
TCTCTGCTTTTTTGTATCTTATCTTGGACACTTATGCTGAATTATGTTCTTATTATTTTCACTGGTTATAAGCTATTCCTTGTACATAAT
ATTTAAACTATCCAAATATCCAGCATACATTTCCATGTGGCTGCCATCGGCTGTTGATGCCATGAATGAAATGGCTGGTTAGAAAGCCAA
AGGTCTTCTTTTTTCAATTCCTAATGAATAAGTAAAATGCCAGATCTCTTTGGTCTCAAAGCAAATTGCTCTGATCAGATCAAATATCTA
TGTAATGAAAAGAGACTTACTTAAATTTGGGATTCTGCTTAAACTTTAAGTTGAATTTGACTGTAGTCATTCATTCTTTTTATATATCTC
TGTCAGGTATGACATTAATTACCAGGTGGTATTATACTCTACTTTGAGTTTGGACATCACTTTCAGTTAAATTTCTGTTGTTATTGTGGC
TTTTTTTTTTTTTTAACCCCACTGAAGATGGAAGTAGAGCAGTCTGCCATCTCCTGCTGTTCTTTCTCTGTGCCCCCTAATTGCTTGGTA
ATCTAAAATTATTCTGACTTTCCACATACTGTCTTTAAAAACCAATTGTAGCAATCTGCCCGCCTCCACCCTTTAAGCTAAATCTTTCAC
TGTGCTGGATACATAGACACTCGATAAATGTGTGATGATAGTTCTAAAATAATTATGCTATATATCAGGGTTCTGTATTTTTGAGCAATA
TCATTATTCCTATGCTGTGATGTTAAATGGAATTTATTTTACACTAGTAATAGACTGCTTAAGTGGCTGATTTGAAACCTTTCTCTAAAA
AAACAAAAACATCTGGCAGATGAGTGACACAAATTCATTCTCTTAAAGGATAGAATTTCAAGTTAAGGATAAGGCACAATAAATAGGCAC
ATAGAGGACATCTGTTTTTGTTTTTGGTTTTGGTTTTGTTTTTTTTTGTCTCTCTGACTAGCTAAACTGCCAACTAGAAGAATGGTTGTT
ATGTAGTAACTCAGAAGAATCTTTTAATAAGTTTCTTCTTTTGTTTCAAAACAAACTTGAGCTTCATTTCTTGCCACCTCTATTCTTTCT
TCCCACGTTGGGTGACTGAACTGATGCTTATTCTAGTTTTAGAAGAGGATCCACATTTAATGTAAGGCATAAATATGCCTTTTGCAAATT
ATTGCTTGTTCTCCAGTGAACATTTGATCATATTCAACAGAAATCCACCATATAAACCATAATCCTTGAATTGCCCCTTTTAAAATAGAT
TGGTTAAAACCAAAAACCTATAAGAGAGAAATGATATTTCATTGTATTGTAGGTTTGGGAATCCTGGTTAGATTTATAATTTCTGGCCGG
GTGCGGTGGCTCATGCCTGTATTCCCAGTACTTTGGGAGCCCAAGGTGGGTGGATCACCTGAGGTAAGGAGTTTGAGACCAGCCTGGCCA
ACATGGTGAAACCCCATCTCTACTAAAAATACAAAAAGTTAGCTGGGCATGGTGGTGCGCGCCTGTGGTCCCAGCTACTCGGGAGGCTGA
GGTGGGAGAATCCCTTGAACCCAGGAGGCAGAAGTTGCAGTGAGCTGAGATCATGCCATTGCACTCCAGCCTGGGCAACAGAGCGAGACT
TCATCTCCAAAAAAAGAAAAAGAAGAAAAAGATTTATAATTTCTGAGTCCCCTAAGTCCCTTTCTCAGTTTGCAATAATCTTACGTCCAT
GCTATTGACACTAATTTTGAAACTGGAAAGCTAATTAATGACATATTCATGTGTTCTTTCATCTAATAAACATTTATTAATGTATAGTTC
TACACCAGGCATTCTGAAGGGTCCAAAAGAAAGTTCCTGCCCTCTAGTAGCACATAATCCGTTATTTCTCAGCACACCATGCCATCTGTT
TATCATTCAGCAGTTAAGTAATTCATCACTTCATATTTTTACCAAAGTATATTTACAAGTCTGTTTATCTGGATCTGGCAAACTGGAAAA
TGTTTGAAGGGATACTCAGGCTTTGATCCATGCCAACATGAAAGGACTCCAAGCACATTTAAGTAGGCTGGTCTTTTCATCATGCATGAT
TTTTTTTTTAGTGCAAATTTAGACTTTAGTTTGGGAAAGAGAACAGTATACAGTATCCTTTGTAAGATAAATCACAACAACAAAAATTAA
GTTTTATTGCACAAAGTAGATAAATGAGAAAGTCTTTCTTAAAAAATGCTTCTTTAACTGTAACAGCAAAACTAAATGCATATTTTATCA
ACCCCTTATTTCTAATTGCTGTATTCATTTCCACCCTTAAACTATTTAAGCATTTCATCTGCTGAAAGTCCTTATATACATGGTAGACGG
AATATTTCTCCATTAATGATAGATCAAAATGAAGATATTTAAAAATTAACAAAATCAGGCCAAGGCAGGAGGATCACTTTAGCCCAGGAG
GTCCAGACCAGCCTGGGCAACACAGCGGGACCCCGACTCCATTTAAAAAATTAAAAAAAAAAAAAAAACTTTTAACATTTAAAAAATAAA
AATTAACAAAATTTCACTTATTCCAGGACACGCTGGCATTTGGACTCAATGAAAAGGGCACCTAAAGAAAATAAGGCTGACTGAATGTTT
TCCATAATTTTCACACAATAACAGTCCCTTTCTATCCAGCTTGCCTTCCATTTATCTCTAGGGTTAGCTTTTCAGGCAACATCCTTGGTC
ATTGCCCAGAAAGTACCTGAGCTATCAGTGATTGGAATGGCACAGGAAACCGAATCACATGGGTGCCCTCCCCTTGGTTTTCAAGTATCT
TGGAGTTGTGCACAAAAATTAGGTCATGCCTTCAGTGTCTTGTTCTTTAAACCTACCCTTTGACAATCAGGTGCTAATGATTGTATACTA
TTAAAACCAGCACATAAGTATTGTAAATGTGTGTTCCTCCTAGGTTGGAAGAAATGTCTTTCCTTCTATCTGGGTCCTGTTAAAGCGGGT
GTCAGTTGTGTCTTTTCACCTCGATTTGTGAATTAATAGAATTGGGGGGAGAGGAAATGATGATGTCAATTAAGTTTCAGGTTTGGCATG
ATCATCATTCTCGATGATATTCTCACTTTGTCGCAAATCTGCCCTTATCGTAAGAACAAGTTTCAGAATTTTCCCTCCACTATACGACTC
CAGTATTATGTTTACAATCCATTGGATGAGTGCAGCATTATAAGACCTTGGTGCCCAGAAAAATCTGTCCTTTTTGGTACCAAACCTGAG
GTCTTTTGGAAGATAATGTAGAAAACCACTACCTATTGAAGGCCTGTTTTGGCTAATCTGTGCAAACTCTGATGATACCTGCTTATGTGG
ATTCTTTTCCACACTGCTTTCATTTTTAAGTATAAAGACTTAGAAAACTAGAATAATGCTTTTACAAATAATTAAAAGTATGTGATGTTC
TGGGTTTTTTCCTTCTTTTTAGAACCCTGTATTTAAACAAGCCTTCTTTTTAAGTCTTGTTTGAAATTTAAGTCTCAGATCTTCTGGATA
CCAAATCAAAAACCCAACGCGTAAAACAGGGCAGTATTTGTGTTCCTAATTTTAAAAAGCTTTATGTATACTCTATAAATATAGATGCAT
AAACAACACTTCCCCTTGAGTAGCACATCAACATACAGCATTGTACATTACAATGAAAATGTGTAACTTAAGGGTATTATATATATAAAT

>20923_20923_3_CYB5B-SNTB2_CYB5B_chr16_69493024_ENST00000561792_SNTB2_chr16_69293953_ENST00000336278_length(amino acids)=396AA_BP=120
MSGSMATAEASGSDGKGQEVETSVTYYRLEEVAKRNSLKELWLVIHGRVYDVTRFLNEHPGGEEVLLEQAGVDASESFEDVGHSSDAREM
LKQYYIGDIHPSDLKPESGSKDPSKNDTCKRLIELHSPDSRNTLILRCKDTATAHSWFVAIHTNIMALLPQVLAELNAMLGATSTAGGSK
EVKHIAWLAEQAKLDGGRQQWRPVLMAVTEKDLLLYDCMPWTRDAWASPCHSYPLVATRLVHSGSGCRSPSLGSDLTFATRTGSRQGIEM
HLFRVETHRDLSSWTRILVQGCHAAAELIKEVSLGCMLNGQEVRLTIHYENGFTISRENGGSSSILYRYPFERLKMSADDGIRNLYLDFG

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Fusion Gene PPI Analysis for CYB5B-SNTB2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CYB5B-SNTB2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CYB5B-SNTB2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource