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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:CYFIP1-FAM189A1 (FusionGDB2 ID:20972) |
Fusion Gene Summary for CYFIP1-FAM189A1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CYFIP1-FAM189A1 | Fusion gene ID: 20972 | Hgene | Tgene | Gene symbol | CYFIP1 | FAM189A1 | Gene ID | 23191 | 23359 |
| Gene name | cytoplasmic FMR1 interacting protein 1 | family with sequence similarity 189 member A1 | |
| Synonyms | P140SRA-1|SHYC|SRA-1|SRA1 | TMEM228 | |
| Cytomap | 15q11.2 | 15q13.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cytoplasmic FMR1-interacting protein 1cytoplasmic FMRP interacting protein 1selective hybridizing clonespecifically Rac1-associated protein 1 | protein FAM189A1transmembrane protein 228 | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | Q7L576 | O60320 | |
| Ensembl transtripts involved in fusion gene | ENST00000313077, ENST00000435939, ENST00000560848, | ENST00000560050, ENST00000261275, | |
| Fusion gene scores | * DoF score | 7 X 9 X 4=252 | 14 X 14 X 3=588 |
| # samples | 6 | 16 | |
| ** MAII score | log2(6/252*10)=-2.0703893278914 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(16/588*10)=-1.877744249949 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: CYFIP1 [Title/Abstract] AND FAM189A1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | CYFIP1(23000243)-FAM189A1(29674035), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across CYFIP1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across FAM189A1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | BRCA | TCGA-A7-A26F-01A | CYFIP1 | chr15 | 23000243 | - | FAM189A1 | chr15 | 29674035 | - |
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Fusion Gene ORF analysis for CYFIP1-FAM189A1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000313077 | ENST00000560050 | CYFIP1 | chr15 | 23000243 | - | FAM189A1 | chr15 | 29674035 | - |
| 5CDS-5UTR | ENST00000435939 | ENST00000560050 | CYFIP1 | chr15 | 23000243 | - | FAM189A1 | chr15 | 29674035 | - |
| 5CDS-5UTR | ENST00000560848 | ENST00000560050 | CYFIP1 | chr15 | 23000243 | - | FAM189A1 | chr15 | 29674035 | - |
| In-frame | ENST00000313077 | ENST00000261275 | CYFIP1 | chr15 | 23000243 | - | FAM189A1 | chr15 | 29674035 | - |
| In-frame | ENST00000435939 | ENST00000261275 | CYFIP1 | chr15 | 23000243 | - | FAM189A1 | chr15 | 29674035 | - |
| In-frame | ENST00000560848 | ENST00000261275 | CYFIP1 | chr15 | 23000243 | - | FAM189A1 | chr15 | 29674035 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000313077 | CYFIP1 | chr15 | 23000243 | - | ENST00000261275 | FAM189A1 | chr15 | 29674035 | - | 8208 | 3722 | 125 | 5122 | 1665 |
| ENST00000560848 | CYFIP1 | chr15 | 23000243 | - | ENST00000261275 | FAM189A1 | chr15 | 29674035 | - | 8274 | 3788 | 122 | 5188 | 1688 |
| ENST00000435939 | CYFIP1 | chr15 | 23000243 | - | ENST00000261275 | FAM189A1 | chr15 | 29674035 | - | 7092 | 2606 | 290 | 4006 | 1238 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000313077 | ENST00000261275 | CYFIP1 | chr15 | 23000243 | - | FAM189A1 | chr15 | 29674035 | - | 0.001171259 | 0.9988287 |
| ENST00000560848 | ENST00000261275 | CYFIP1 | chr15 | 23000243 | - | FAM189A1 | chr15 | 29674035 | - | 0.001357396 | 0.9986426 |
| ENST00000435939 | ENST00000261275 | CYFIP1 | chr15 | 23000243 | - | FAM189A1 | chr15 | 29674035 | - | 0.00138776 | 0.99861217 |
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Fusion Genomic Features for CYFIP1-FAM189A1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for CYFIP1-FAM189A1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:23000243/chr15:29674035) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CYFIP1 | FAM189A1 |
| FUNCTION: Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). May act as an invasion suppressor in cancers. {ECO:0000250|UniProtKB:Q7TMB8, ECO:0000269|PubMed:16260607, ECO:0000269|PubMed:19524508, ECO:0000269|PubMed:21107423, ECO:0000269|PubMed:9417078}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | FAM189A1 | chr15:23000243 | chr15:29674035 | ENST00000261275 | 0 | 11 | 242_391 | 73 | 540.0 | Compositional bias | Note=Pro-rich | |
| Tgene | FAM189A1 | chr15:23000243 | chr15:29674035 | ENST00000261275 | 0 | 11 | 176_196 | 73 | 540.0 | Transmembrane | Helical | |
| Tgene | FAM189A1 | chr15:23000243 | chr15:29674035 | ENST00000261275 | 0 | 11 | 89_109 | 73 | 540.0 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | FAM189A1 | chr15:23000243 | chr15:29674035 | ENST00000261275 | 0 | 11 | 31_51 | 73 | 540.0 | Transmembrane | Helical | |
| Tgene | FAM189A1 | chr15:23000243 | chr15:29674035 | ENST00000261275 | 0 | 11 | 65_85 | 73 | 540.0 | Transmembrane | Helical |
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Fusion Gene Sequence for CYFIP1-FAM189A1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >20972_20972_1_CYFIP1-FAM189A1_CYFIP1_chr15_23000243_ENST00000313077_FAM189A1_chr15_29674035_ENST00000261275_length(transcript)=8208nt_BP=3722nt CGGGAGGAAGGGGAGGAGGCCGAGTGTTTCCTGGCGCATTCCCGGCCAGCCCGAGTGACTCACTCGGCCAAGGAAACTCCCAGGGCCCGC CCAGGACCCCCAAGCCGCCGCGGACGCAGCCCAGGATGGCGGCCCAGGTGACTCTGGAGGACGCGCTGTCCAACGTGGACCTCCTGGAGG AGCTGCCCCTGCCCGACCAGCAGCCCTGCATCGAGCCCCCGCCATCCTCGCTGCTCTACCAGCCAAATTTCAACACTAACTTTGAAGACA GAAATGCATTTGTTACTGGCATCGCAAGATACATTGAACAAGCCACCGTCCACTCTAGCATGAACGAGATGCTGGAGGAGGGCCAAGAAT ATGCTGTCATGCTGTACACCTGGAGGAGCTGCTCCCGGGCCATCCCACAGGTGAAATGTAACGAGCAGCCTAACAGAGTGGAAATCTACG AGAAAACCGTGGAGGTTCTGGAGCCTGAGGTCACAAAACTGATGAATTTCATGTACTTCCAGAGAAATGCCATTGAGCGTTTCTGCGGGG AAGTGAGGCGCCTGTGCCATGCCGAGAGGAGGAAGGACTTCGTGTCAGAAGCCTACCTGATCACACTGGGCAAATTCATCAACATGTTCG CTGTGCTGGACGAGCTGAAGAACATGAAGTGCAGTGTGAAGAACGACCACTCAGCGTACAAGAGGGCCGCTCAGTTTTTACGTAAAATGG CAGATCCACAGTCCATCCAGGAATCGCAGAATCTGTCCATGTTCCTGGCCAATCATAACAAGATCACACAGTCTCTGCAGCAGCAGCTCG AAGTGATTTCTGGCTACGAAGAGCTCCTGGCAGATATTGTGAATCTGTGTGTGGATTACTACGAGAACAGGATGTATTTGACGCCCAGTG AGAAACACATGCTTCTCAAAGTCATGGGATTTGGTCTGTACCTGATGGATGGGAGTGTCAGTAACATCTATAAGTTGGATGCCAAGAAAA GAATAAACTTATCCAAAATCGACAAGTACTTCAAGCAACTCCAGGTGGTTCCGCTATTTGGGGACATGCAAATAGAACTGGCAAGATATA TCAAGACCAGCGCCCACTACGAGGAAAATAAATCTCGATGGACGTGCACATCCTCCGGCAGCAGCCCTCAGTACAACATCTGCGAGCAGA TGATCCAGATCCGCGAGGACCACATGCGCTTCATTTCGGAGCTGGCGCGCTACAGCAACAGCGAGGTGGTCACGGGCTCGGGCCGCCAGG AGGCCCAGAAGACGGACGCGGAGTACCGCAAGCTCTTCGACCTGGCGCTGCAGGGCCTGCAGCTGTTGTCGCAGTGGAGCGCGCACGTGA TGGAAGTGTATTCCTGGAAGCTTGTGCACCCCACCGACAAGTACTCCAACAAGGACTGCCCCGACAGCGCTGAAGAGTACGAGCGTGCCA CGCGCTACAACTACACCAGCGAGGAGAAGTTTGCCCTAGTGGAGGTGATCGCCATGATCAAAGGCCTGCAGGTGCTGATGGGCAGGATGG AGAGCGTGTTCAACCACGCCATCCGGCACACCGTCTATGCCGCACTGCAGGACTTCTCCCAGGTGACCCTTAGGGAGCCGCTGCGGCAGG CCATCAAGAAGAAGAAGAACGTCATCCAGAGTGTCCTGCAGGCCATCAGGAAGACCGTGTGTGACTGGGAGACGGGGCATGAGCCCTTCA ATGACCCAGCCTTGCGGGGCGAGAAGGACCCCAAGAGCGGCTTCGACATAAAAGTACCACGCCGCGCCGTGGGACCCTCCAGCACTCAGC TTTACATGGTGAGAACCATGCTAGAGTCCCTCATTGCAGACAAAAGTGGTTCCAAGAAAACCTTGAGAAGTAGCCTTGAGGGGCCCACCA TATTGGACATAGAAAAATTTCATCGAGAGTCATTCTTCTACACTCACTTGATAAATTTCAGTGAAACGCTGCAGCAGTGCTGTGACCTTT CGCAGCTGTGGTTCCGAGAGTTCTTCCTGGAGCTGACCATGGGCAGGAGGATCCAGTTCCCCATTGAGATGTCGATGCCCTGGATCCTGA CGGACCACATCCTGGAGACCAAGGAGGCATCGATGATGGAGTACGTGCTCTACTCCCTGGACCTGTACAATGACAGCGCCCACTACGCGC TCACCAGGTTCAACAAGCAGTTCCTGTACGACGAAATTGAGGCCGAGGTGAATCTATGTTTTGACCAATTTGTTTACAAGCTAGCAGACC AGATATTTGCCTATTATAAGGTTATGGCAGGAAGTTTGCTTCTTGATAAACGGTTACGATCAGAATGCAAGAATCAGGGAGCCACGATCC ACCTCCCGCCGTCTAACCGCTACGAGACGCTGCTGAAGCAGAGGCATGTGCAGCTCCTCGGCAGATCAATAGACCTCAATCGTCTGATCA CCCAGCGCGTCTCAGCAGCCATGTATAAGTCCCTAGAACTGGCGATTGGACGATTTGAAAGTGAAGATTTGACCTCCATAGTTGAGCTGG ATGGCCTGTTGGAAATCAACCGCATGACCCACAAGCTGCTGAGCCGGTACCTGACGCTGGACGGCTTCGACGCCATGTTCCGGGAGGCCA ACCACAACGTGTCAGCGCCCTACGGGAGGATCACCCTGCACGTCTTCTGGGAGCTCAACTATGACTTCCTGCCCAACTACTGCTACAACG GCTCTACCAACCGGTTTGTTCGGACAGTGTTACCATTTTCTCAGGAATTTCAAAGAGATAAGCAGCCTAATGCACAGCCTCAGTATCTGC ATGGATCCAAGGCTTTGAACTTGGCCTACTCCAGCATTTACGGCAGCTACCGGAACTTCGTGGGACCTCCACACTTTCAAGTCATCTGCC GGCTTCTCGGCTACCAGGGTATCGCCGTGGTCATGGAGGAGCTGCTGAAGGTCGTCAAGAGCCTGCTGCAAGGCACAATCCTGCAGTACG TGAAGACGCTGATGGAGGTGATGCCCAAGATCTGCCGCCTGCCCCGGCACGAGTACGGCTCTCCTGGTATCCTGGAGTTCTTCCACCACC AGCTGAAGGACATCGTGGAGTACGCAGAGCTGAAGACGGTGTGCTTCCAGAACCTGCGGGAGGTGGGGAACGCCATCCTCTTCTGCCTGC TCATCGAGCAGAGCCTGTCTTTAGAAGAAGTGTGTGACCTGCTGCACGCGGCTCCTTTCCAGAACATCTTGCCGCGAGTCCATGTGAAAG AGGGGGAGAGACTTGATGCCAAAATGAAAAGACTAGAATCAAAGTACGCCCCGCTGCATCTTGTCCCACTGATTGAAAGACTGGGGACCC CTCAGCAAATTGCCATCGCAAGAGAGGGGGACCTGCTGACAAAGGAGCGCCTCTGCTGCGGCCTGTCCATGTTTGAGGTCATCCTGACAC GGATCCGGAGCTTTCTGGATGACCCCATCTGGCGCGGGCCTCTGCCCAGCAATGGGGTCATGCATGTGGACGAGTGTGTGGAGTTTCACA GACTGTGGAGTGCCATGCAGTTTGTCTACTGCATTCCCGTGGGGACACACGAGTTCACAGTCGAGCAGTGCTTTGGTGATGGGCTACACT GGGCTGGCTGTATGATCATCGTACTTCTTGGGCAGCAGCGGCGTTTTGCTGTGCTGGATTTCTGCTACCATCTACTTAAAGTCCAGAAAC ATGATGGCAAAGATGAGATTATTAAAAATGTGGTGCTGCTGTCGGGACTCATAGGTGTCGTCTCCTGGAAGAGGCCTCTCTCCCTTGTGA TAACCTTTTTCATGCTGCTTTCTGCAGTGTGTGTAATGCTGAATTTGGCTGGTTCAATTCTCTCTTGTCAGAATGCTCAGCTAGTCAACT CCCTAGAAGGCTGCCAGTTGATTAAGTTTGACAGTGTGGAGGTGTGTGTCTGCTGTGAGCTGCAGCACCAGTCGTCCGGCTGCAGCAACC TCGGGGAGACGCTGAAGCTGAACCCGCTGCAGGAGAACTGCAACGCTGTGAGGCTGACCTTGAAGGATCTCCTCTTCAGCGTGTGTGCCC TCAACGTCCTGTCCACTATCGTGTGTGCGCTGGCCACAGCCATGTGCTGTATGCAGATGGTCTCCTCCGATGTCCTGCAGATGTTCCTTC CGCAGAGGTCACATCCTGCCAACCCCACCTGCGTGACTCCTCACGGCACCGTTCTCCACCAGACCCTGGATTTCGACGAGTTCATCCCCC CACTCCCGCCTCCACCCTATTACCCCCCAGAGTACACCTGCACACCGTCCACTGAGGCCCAGAGGGGCCTCCACCTGGACTTTGCTCCGT CTCCATTCGGCACTTTGTATGACGTGGCCATCAATAGCCCCGGCCTGCTCTATCCTGCTGAGCTCCCCCCTCCGTACGAGGCGGTGGTGG GCCAGCCCCCTGCCAGCCAGGTTACAAGTATAGGTCAGCAGGTGGCCGAGTCCAGCTCCGGGGACCCAAACACCAGTGCTGGCTTCAGCA CTCCAGTACCAGCTGACAGCACAAGCCTCCTGGTGTCCGAGGGCACTGCTACGCCAGGTTCCAGCCCATCCCCCGATGGCCCTGTGGGCG CCCCAGCACCCTCCGAACCTGCCCTTCCCCCTGGCCATGTGTCTCCAGAGGATCCTGGCATGGGCTCACAGGTGCAGCCAGGTCCCGGGC GTGTGTCCCGCTCCACCAGCGACCCCACCTTGTGCACATCTAGCATGGCAGGCGATGCCTCTTCACACAGGCCGTCGTGTAGCCAGGACC TGGAAGCGGGACTGTCTGAGGCTGTGCCTGGGAGCGCTTCCATGTCTCGCTCTGCCACGGCTGCCTGTCGGGCCCAGCTTTCACCAGCGG GGGACCCAGATACCTGGAAAACTGACCAACGGCCAACACCAGAGCCCTTCCCAGCGACCTCCAAAGAGCGGCCACGCTCTTTAGTGGACA GCAAGGCCTATGCGGATGCCAGGGTTTTGGTGGCCAAGTTTTTGGAACACTCACACTGTGCCCTCCCCACCGAGGCACAGCACATGGTGG GTGCCATGCGCTTGGCTGTCACCAACGAGGAGCGCCTCGAGGAGGAGGCCGTCTTCGGCGCTGACGTTCTGGACCAGGTATGAAGGAGCC ACATTTCTGACCGTGGACACCAACGCCTGGCGCCACAGATGTTCTTGGCAGAAGCCATCATGCCTGACAAAGAGGCCTTCAGGCCCAGCT TGGCGGAGGATAAATGTGGGGGGGACACCCAGGATGATCTGGGGGCGGTGTGGGCAGGGAACTGTTACCCCCTCTCTCGAGGGGAGCCGA GCAGTGTCTCTTTGGGGATTGCATTTCCTGCCTAGCCCAGTAATTCGGAAAGATGACTTTCACGTCCACAGTGAACTCTCTGGTTTTATC TGGCGTGCAGCACCTTGAACTGAGCAGTGTTGCACAAATGTGAATACAGCAACAGGCGACACTTACGTCACCTAAAGACTCAAAGTATCT CCAAAATCAGGGCCTTCCAAAGCAGGAGTCTCCCATCCCCCATTTAACTTAGTGTTCAGTGGACAGAGGGTGACATCGAGTCATGAAACA TTTTCTCATGTGGCTCGATGGCTCTATCATTAGGCGTTCATCACGCTCTGGCCTATTTCCTGTGAAAGGAAATAGGTAGTGTTAGCACAG ATGGCAGCCTGGGCCCAACTTTCTGTCCACAGGGCTATTGTGCAAACAAATGTGCAGTGCGGGCCTCTGCCATAGCCCGGCCCCCCCCAG GGAACAGGCCGGTGTTGCGGGGGTTGGAGGAACCCACCATCTCCTGGGCCTTGAGCTCGGCCTCCCTCCGTGGGGTGCCTTCCCCCCCTC CTCTTGGGCCCCCTTTCTCCAGGCTCCCATCCTGTCCCTGGAGCAGTTGTGTGATCCGTAACAACAAGTGCCGATTCCCAGCTCCTTTGT GTCTGAGCTCACTTGATTGAGCTCAGCGGGTCACAGTTCTGCAGGAGAGAGGCCGGTTTCTCTGAGAAGTAGCCCCTCCTGATAAAGCAG GTCCCTTTGACCCAGAGCTGACCTTTCCCCGGGCATGCGGCAGCAGACACACCTGCGCAGGAGGATCATAAACCACTTACAAACCCACAC GAGAAGGGAAGCAGACACCCAACGTGCTGCTTATGGAGAAGCAGACACGCCCAGCTTGGGGACAGCCTGGGGACCTTGGACTTTCTTAGC CCCCATCCCCTTGTTTTCTGGTGGCATCAGTGGCAGCTGCTCCCAACAATGGCCGTGGAACAGCGCCATCCACGAGAACTTTGTGCAGTG ATGGAAATGCCTGTTCAGGGCCACTAGCAGCCACAGCCCCTGAGCTGCGTTGGGTGGGCCCTGCGGTGAACAAAACAGCCTAGAGGCCAA GGTCTCCCCAGAGAGCCCATGAGCCTGGCATGGGGGCGCAGGGGGACCAGAGGGTGTCTTCCACTCCTGGGTGCCAGGGCAGGGGGCTCA CGCTGCTGTTCCCTCGGCTTTGTGGGGCTTGTCCTTGAGCTCCCCCAATTCCCTAATGCCACTGTGGCCAGTGTGCTGGGGAGCTTCTGT GTGGCTGGAAGCTGGGAAGGGGGTGAGGTTCCAATCCAGGTGCCCAGAGCCTTCCTCCAGTCCTTTATCCCTGCCCTGGGGGCTGCGGTG TGGGACTCCTTCAGCTGTGGTCGGCTGAAAAGGCTTCGATTGCTTTAGAGAGCTGAAAACACATAAGCCAGGCCTTTTGATGACAACCTG CACTTTTGCAGGAGAGACGTACTAGAGATGAATTTTTGAGCACTTTATTCAGACTATAAAACAGGAAATCTCTAATTTTCCTCAAGTGGG GGCTTTTGAATTCCCTCAAGGCAAGTCCCTTTGCAGGTGAAATTAATTGGTGGATTTTCAGAATGGCCGCCCTGGAGCCGAGCTTCAGCC ACGCCTGACGCCCTGGCCTCTGAATCTCCACTGTCTCTGAGGTGCGCTGGGGCCACGCCGCAGGGGTTTCACCTGCTTGGGGGGGTCCAC ACTAGGGCTTGGGGGTTCACACAGCATTGTCCCTGGGCTGAGCCCTTGGGTGGGCTAGAGCTGCAGTCCTCAGACATGGCTGCAATTCCA GCGAGGCCAAGACCACCAGCCACCCAGTGGACTCGGTCTCTGGGGTGTTCTCCTCATGCAGCCGGGGCAGAGGCCTACTGGACCCCCTCA GCCTGCTGCTCAGCATCCTTCCCTTCTCTGCAGCAGGGCCCGGTCCCAATGGCCAATGGGGCTGCTGCCCCAGCAGTGCCTCCCTGTAGG CCCCTCACCTGCACCCCACCTTCACCCAGCTCTGGGTTTGCGCTGGTGGCAGCTCTGTTTTGTGGATACGGAAACTGTACCCAACTTGAT GCCGCTGGGCTGGAACCTTCTGCCCCTTCGAAATGAGGCAGTCAGGGACGGGGTGGGGTGCCCCCATCAGCCCCGCTGCTCAGGGCCACT CATGGACTCTAGGAGGGTCCAGGTTCTGGGCTTCCTGGGAAGGTCCCCAGAAGAGAGAGGTGCTGGTAGACTAGGGAATGTGCTGGCAAC TTGACCCAGAAGCTGTGGTCCCCTTGGCCCCGGCTCCACGGCATCCGGGTACCAGCAGCAAGAGCCCAGGCCCCGGGCTGCACGTCAGCT CACAGCCCAGGAGAAAGCTGGCTGCTTCCCCTCCCTATGCGTCTTTCCCCCGCTCCAATCATGTTCCATCTGGGATCTGAAATGGGCCAA CTGTGGCTGCTTTGGGGGTGACACGCTCCTTCTCCAACTCAGCTGGGCCCCGGGCATCCCCTGCCCTCCCCTGAGACCCAAAGGGGGTTG GCACCTGCTGTGACACCACCGTTGACCCCAGCCTGGGGGCCACAAGGTTGCTGAGTGGGGAGAACATGGACCCCAACTCTATGGCAAGCA AGATCGCAGAAGGGGGAGCATCATCCGCAAGGACTTCAGGTCTCCCTTGGCTGGAGATGAGGATCCACATTAAATGCTTGTAACACACCA GGCCACAGAAAGCTCGCTACACACACATGCTTCTCCCCACCCATGCTGACTCTCAGAGGCTGCTAAGGCAGAATTTATAGGAAATTGTTT TCAAGCCACCAGAGACCTGTCTGTACAACTGGAAAGGCTGTATTTATTTAATGTACCTCAAGGTGTTTTAATAATGATCCGTGTTTTAAT >20972_20972_1_CYFIP1-FAM189A1_CYFIP1_chr15_23000243_ENST00000313077_FAM189A1_chr15_29674035_ENST00000261275_length(amino acids)=1665AA_BP=1199 MAAQVTLEDALSNVDLLEELPLPDQQPCIEPPPSSLLYQPNFNTNFEDRNAFVTGIARYIEQATVHSSMNEMLEEGQEYAVMLYTWRSCS RAIPQVKCNEQPNRVEIYEKTVEVLEPEVTKLMNFMYFQRNAIERFCGEVRRLCHAERRKDFVSEAYLITLGKFINMFAVLDELKNMKCS VKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNKITQSLQQQLEVISGYEELLADIVNLCVDYYENRMYLTPSEKHMLLKVMGFG LYLMDGSVSNIYKLDAKKRINLSKIDKYFKQLQVVPLFGDMQIELARYIKTSAHYEENKSRWTCTSSGSSPQYNICEQMIQIREDHMRFI SELARYSNSEVVTGSGRQEAQKTDAEYRKLFDLALQGLQLLSQWSAHVMEVYSWKLVHPTDKYSNKDCPDSAEEYERATRYNYTSEEKFA LVEVIAMIKGLQVLMGRMESVFNHAIRHTVYAALQDFSQVTLREPLRQAIKKKKNVIQSVLQAIRKTVCDWETGHEPFNDPALRGEKDPK SGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLEGPTILDIEKFHRESFFYTHLINFSETLQQCCDLSQLWFREFFLEL TMGRRIQFPIEMSMPWILTDHILETKEASMMEYVLYSLDLYNDSAHYALTRFNKQFLYDEIEAEVNLCFDQFVYKLADQIFAYYKVMAGS LLLDKRLRSECKNQGATIHLPPSNRYETLLKQRHVQLLGRSIDLNRLITQRVSAAMYKSLELAIGRFESEDLTSIVELDGLLEINRMTHK LLSRYLTLDGFDAMFREANHNVSAPYGRITLHVFWELNYDFLPNYCYNGSTNRFVRTVLPFSQEFQRDKQPNAQPQYLHGSKALNLAYSS IYGSYRNFVGPPHFQVICRLLGYQGIAVVMEELLKVVKSLLQGTILQYVKTLMEVMPKICRLPRHEYGSPGILEFFHHQLKDIVEYAELK TVCFQNLREVGNAILFCLLIEQSLSLEEVCDLLHAAPFQNILPRVHVKEGERLDAKMKRLESKYAPLHLVPLIERLGTPQQIAIAREGDL LTKERLCCGLSMFEVILTRIRSFLDDPIWRGPLPSNGVMHVDECVEFHRLWSAMQFVYCIPVGTHEFTVEQCFGDGLHWAGCMIIVLLGQ QRRFAVLDFCYHLLKVQKHDGKDEIIKNVVLLSGLIGVVSWKRPLSLVITFFMLLSAVCVMLNLAGSILSCQNAQLVNSLEGCQLIKFDS VEVCVCCELQHQSSGCSNLGETLKLNPLQENCNAVRLTLKDLLFSVCALNVLSTIVCALATAMCCMQMVSSDVLQMFLPQRSHPANPTCV TPHGTVLHQTLDFDEFIPPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYPAELPPPYEAVVGQPPASQVTSIG QQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSSPSPDGPVGAPAPSEPALPPGHVSPEDPGMGSQVQPGPGRVSRSTSDPTLC TSSMAGDASSHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKTDQRPTPEPFPATSKERPRSLVDSKAYADARVLVA -------------------------------------------------------------- >20972_20972_2_CYFIP1-FAM189A1_CYFIP1_chr15_23000243_ENST00000435939_FAM189A1_chr15_29674035_ENST00000261275_length(transcript)=7092nt_BP=2606nt CCGGTTTAATCCACACCGCTGCGTCTGTCCTCCGTCCTGGGGCTGGTCTTCTCCCTCATCTCTGCCGGAGGCTTTTAATCTCTTCTGCCA CTCTTCTGGAAAGTCACCAGCAATGCACGCTGCTGGCTCTGCAGGAGGGTCAGGGGGACGGCCCTCGGCCTGTGCGTGGTGCCAGCCACC CTCCCTGCCTCCCTCTGCGTGCGTCCCGTGTCCCTGCCTGGGGTGTGTGTGTCGAGTGACTAACGTCTCTCTCCTGCCTCTCCCTCCTGT CTGTCCGTGTCTAGCTCTACCTGGTGCGCACCATGGCCGAGTCCTTGGGCTCTGCCGAGCTGCTCAGGCAGCTCAAGTCTCTGGGCATGG AGAGGCTCTTGCATGCGGTTAACACGTTTCTGAGGCAGTCGTGCACCTACCTACCCCTTTTAACCTTTGGTGGTAAGACATCATTTGTTT CTCTTGACGTTTATGGCACGGAGGCGAACTGCTCCGCTACAAGTTGTTCTTTCCCCAAAGCAGCAGCAACGTGGCCGCGTAGACAGGCAC CCGGACCCCTCGGGGAGCTGGTGCGGGGCCCTCCCGACCAGGGCGTAGCGGAGCAGTCCTTCTCTCATGGGCTTTTTGAGTTTGGCATAA CTAATGTACCATGTATATTTTCTCCCCCACAAATGTTTCCTTGGATAATCCAGCTTTACATGGTGAGAACCATGCTAGAGTCCCTCATTG CAGACAAAAGTGGTTCCAAGAAAACCTTGAGAAGTAGCCTTGAGGGGCCCACCATATTGGACATAGAAAAATTTCATCGAGAGTCATTCT TCTACACTCACTTGATAAATTTCAGTGAAACGCTGCAGCAGTGCTGTGACCTTTCGCAGCTGTGGTTCCGAGAGTTCTTCCTGGAGCTGA CCATGGGCAGGAGGATCCAGTTCCCCATTGAGATGTCGATGCCCTGGATCCTGACGGACCACATCCTGGAGACCAAGGAGGCATCGATGA TGGAGTACGTGCTCTACTCCCTGGACCTGTACAATGACAGCGCCCACTACGCGCTCACCAGGTTCAACAAGCAGTTCCTGTACGACGAAA TTGAGGCCGAGGTGAATCTATGTTTTGACCAATTTGTTTACAAGCTAGCAGACCAGATATTTGCCTATTATAAGGTTATGGCAGGAAGTT TGCTTCTTGATAAACGGTTACGATCAGAATGCAAGAATCAGGGAGCCACGATCCACCTCCCGCCGTCTAACCGCTACGAGACGCTGCTGA AGCAGAGGCATGTGCAGCTCCTCGGCAGATCAATAGACCTCAATCGTCTGATCACCCAGCGCGTCTCAGCAGCCATGTATAAGTCCCTAG AACTGGCGATTGGACGATTTGAAAGTGAAGATTTGACCTCCATAGTTGAGCTGGATGGCCTGTTGGAAATCAACCGCATGACCCACAAGC TGCTGAGCCGGTACCTGACGCTGGACGGCTTCGACGCCATGTTCCGGGAGGCCAACCACAACGTGTCAGCGCCCTACGGGAGGATCACCC TGCACGTCTTCTGGGAGCTCAACTATGACTTCCTGCCCAACTACTGCTACAACGGCTCTACCAACCGGTTTGTTCGGACAGTGTTACCAT TTTCTCAGGAATTTCAAAGAGATAAGCAGCCTAATGCACAGCCTCAGTATCTGCATGGATCCAAGGCTTTGAACTTGGCCTACTCCAGCA TTTACGGCAGCTACCGGAACTTCGTGGGACCTCCACACTTTCAAGTCATCTGCCGGCTTCTCGGCTACCAGGGTATCGCCGTGGTCATGG AGGAGCTGCTGAAGGTCGTCAAGAGCCTGCTGCAAGGCACAATCCTGCAGTACGTGAAGACGCTGATGGAGGTGATGCCCAAGATCTGCC GCCTGCCCCGGCACGAGTACGGCTCTCCTGGTATCCTGGAGTTCTTCCACCACCAGCTGAAGGACATCGTGGAGTACGCAGAGCTGAAGA CGGTGTGCTTCCAGAACCTGCGGGAGGTGGGGAACGCCATCCTCTTCTGCCTGCTCATCGAGCAGAGCCTGTCTTTAGAAGAAGTGTGTG ACCTGCTGCACGCGGCTCCTTTCCAGAACATCTTGCCGCGAGTCCATGTGAAAGAGGGGGAGAGACTTGATGCCAAAATGAAAAGACTAG AATCAAAGTACGCCCCGCTGCATCTTGTCCCACTGATTGAAAGACTGGGGACCCCTCAGCAAATTGCCATCGCAAGAGAGGGGGACCTGC TGACAAAGGAGCGCCTCTGCTGCGGCCTGTCCATGTTTGAGGTCATCCTGACACGGATCCGGAGCTTTCTGGATGACCCCATCTGGCGCG GGCCTCTGCCCAGCAATGGGGTCATGCATGTGGACGAGTGTGTGGAGTTTCACAGACTGTGGAGTGCCATGCAGTTTGTCTACTGCATTC CCGTGGGGACACACGAGTTCACAGTCGAGCAGTGCTTTGGTGATGGGCTACACTGGGCTGGCTGTATGATCATCGTACTTCTTGGGCAGC AGCGGCGTTTTGCTGTGCTGGATTTCTGCTACCATCTACTTAAAGTCCAGAAACATGATGGCAAAGATGAGATTATTAAAAATGTGGTGC TGCTGTCGGGACTCATAGGTGTCGTCTCCTGGAAGAGGCCTCTCTCCCTTGTGATAACCTTTTTCATGCTGCTTTCTGCAGTGTGTGTAA TGCTGAATTTGGCTGGTTCAATTCTCTCTTGTCAGAATGCTCAGCTAGTCAACTCCCTAGAAGGCTGCCAGTTGATTAAGTTTGACAGTG TGGAGGTGTGTGTCTGCTGTGAGCTGCAGCACCAGTCGTCCGGCTGCAGCAACCTCGGGGAGACGCTGAAGCTGAACCCGCTGCAGGAGA ACTGCAACGCTGTGAGGCTGACCTTGAAGGATCTCCTCTTCAGCGTGTGTGCCCTCAACGTCCTGTCCACTATCGTGTGTGCGCTGGCCA CAGCCATGTGCTGTATGCAGATGGTCTCCTCCGATGTCCTGCAGATGTTCCTTCCGCAGAGGTCACATCCTGCCAACCCCACCTGCGTGA CTCCTCACGGCACCGTTCTCCACCAGACCCTGGATTTCGACGAGTTCATCCCCCCACTCCCGCCTCCACCCTATTACCCCCCAGAGTACA CCTGCACACCGTCCACTGAGGCCCAGAGGGGCCTCCACCTGGACTTTGCTCCGTCTCCATTCGGCACTTTGTATGACGTGGCCATCAATA GCCCCGGCCTGCTCTATCCTGCTGAGCTCCCCCCTCCGTACGAGGCGGTGGTGGGCCAGCCCCCTGCCAGCCAGGTTACAAGTATAGGTC AGCAGGTGGCCGAGTCCAGCTCCGGGGACCCAAACACCAGTGCTGGCTTCAGCACTCCAGTACCAGCTGACAGCACAAGCCTCCTGGTGT CCGAGGGCACTGCTACGCCAGGTTCCAGCCCATCCCCCGATGGCCCTGTGGGCGCCCCAGCACCCTCCGAACCTGCCCTTCCCCCTGGCC ATGTGTCTCCAGAGGATCCTGGCATGGGCTCACAGGTGCAGCCAGGTCCCGGGCGTGTGTCCCGCTCCACCAGCGACCCCACCTTGTGCA CATCTAGCATGGCAGGCGATGCCTCTTCACACAGGCCGTCGTGTAGCCAGGACCTGGAAGCGGGACTGTCTGAGGCTGTGCCTGGGAGCG CTTCCATGTCTCGCTCTGCCACGGCTGCCTGTCGGGCCCAGCTTTCACCAGCGGGGGACCCAGATACCTGGAAAACTGACCAACGGCCAA CACCAGAGCCCTTCCCAGCGACCTCCAAAGAGCGGCCACGCTCTTTAGTGGACAGCAAGGCCTATGCGGATGCCAGGGTTTTGGTGGCCA AGTTTTTGGAACACTCACACTGTGCCCTCCCCACCGAGGCACAGCACATGGTGGGTGCCATGCGCTTGGCTGTCACCAACGAGGAGCGCC TCGAGGAGGAGGCCGTCTTCGGCGCTGACGTTCTGGACCAGGTATGAAGGAGCCACATTTCTGACCGTGGACACCAACGCCTGGCGCCAC AGATGTTCTTGGCAGAAGCCATCATGCCTGACAAAGAGGCCTTCAGGCCCAGCTTGGCGGAGGATAAATGTGGGGGGGACACCCAGGATG ATCTGGGGGCGGTGTGGGCAGGGAACTGTTACCCCCTCTCTCGAGGGGAGCCGAGCAGTGTCTCTTTGGGGATTGCATTTCCTGCCTAGC CCAGTAATTCGGAAAGATGACTTTCACGTCCACAGTGAACTCTCTGGTTTTATCTGGCGTGCAGCACCTTGAACTGAGCAGTGTTGCACA AATGTGAATACAGCAACAGGCGACACTTACGTCACCTAAAGACTCAAAGTATCTCCAAAATCAGGGCCTTCCAAAGCAGGAGTCTCCCAT CCCCCATTTAACTTAGTGTTCAGTGGACAGAGGGTGACATCGAGTCATGAAACATTTTCTCATGTGGCTCGATGGCTCTATCATTAGGCG TTCATCACGCTCTGGCCTATTTCCTGTGAAAGGAAATAGGTAGTGTTAGCACAGATGGCAGCCTGGGCCCAACTTTCTGTCCACAGGGCT ATTGTGCAAACAAATGTGCAGTGCGGGCCTCTGCCATAGCCCGGCCCCCCCCAGGGAACAGGCCGGTGTTGCGGGGGTTGGAGGAACCCA CCATCTCCTGGGCCTTGAGCTCGGCCTCCCTCCGTGGGGTGCCTTCCCCCCCTCCTCTTGGGCCCCCTTTCTCCAGGCTCCCATCCTGTC CCTGGAGCAGTTGTGTGATCCGTAACAACAAGTGCCGATTCCCAGCTCCTTTGTGTCTGAGCTCACTTGATTGAGCTCAGCGGGTCACAG TTCTGCAGGAGAGAGGCCGGTTTCTCTGAGAAGTAGCCCCTCCTGATAAAGCAGGTCCCTTTGACCCAGAGCTGACCTTTCCCCGGGCAT GCGGCAGCAGACACACCTGCGCAGGAGGATCATAAACCACTTACAAACCCACACGAGAAGGGAAGCAGACACCCAACGTGCTGCTTATGG AGAAGCAGACACGCCCAGCTTGGGGACAGCCTGGGGACCTTGGACTTTCTTAGCCCCCATCCCCTTGTTTTCTGGTGGCATCAGTGGCAG CTGCTCCCAACAATGGCCGTGGAACAGCGCCATCCACGAGAACTTTGTGCAGTGATGGAAATGCCTGTTCAGGGCCACTAGCAGCCACAG CCCCTGAGCTGCGTTGGGTGGGCCCTGCGGTGAACAAAACAGCCTAGAGGCCAAGGTCTCCCCAGAGAGCCCATGAGCCTGGCATGGGGG CGCAGGGGGACCAGAGGGTGTCTTCCACTCCTGGGTGCCAGGGCAGGGGGCTCACGCTGCTGTTCCCTCGGCTTTGTGGGGCTTGTCCTT GAGCTCCCCCAATTCCCTAATGCCACTGTGGCCAGTGTGCTGGGGAGCTTCTGTGTGGCTGGAAGCTGGGAAGGGGGTGAGGTTCCAATC CAGGTGCCCAGAGCCTTCCTCCAGTCCTTTATCCCTGCCCTGGGGGCTGCGGTGTGGGACTCCTTCAGCTGTGGTCGGCTGAAAAGGCTT CGATTGCTTTAGAGAGCTGAAAACACATAAGCCAGGCCTTTTGATGACAACCTGCACTTTTGCAGGAGAGACGTACTAGAGATGAATTTT TGAGCACTTTATTCAGACTATAAAACAGGAAATCTCTAATTTTCCTCAAGTGGGGGCTTTTGAATTCCCTCAAGGCAAGTCCCTTTGCAG GTGAAATTAATTGGTGGATTTTCAGAATGGCCGCCCTGGAGCCGAGCTTCAGCCACGCCTGACGCCCTGGCCTCTGAATCTCCACTGTCT CTGAGGTGCGCTGGGGCCACGCCGCAGGGGTTTCACCTGCTTGGGGGGGTCCACACTAGGGCTTGGGGGTTCACACAGCATTGTCCCTGG GCTGAGCCCTTGGGTGGGCTAGAGCTGCAGTCCTCAGACATGGCTGCAATTCCAGCGAGGCCAAGACCACCAGCCACCCAGTGGACTCGG TCTCTGGGGTGTTCTCCTCATGCAGCCGGGGCAGAGGCCTACTGGACCCCCTCAGCCTGCTGCTCAGCATCCTTCCCTTCTCTGCAGCAG GGCCCGGTCCCAATGGCCAATGGGGCTGCTGCCCCAGCAGTGCCTCCCTGTAGGCCCCTCACCTGCACCCCACCTTCACCCAGCTCTGGG TTTGCGCTGGTGGCAGCTCTGTTTTGTGGATACGGAAACTGTACCCAACTTGATGCCGCTGGGCTGGAACCTTCTGCCCCTTCGAAATGA GGCAGTCAGGGACGGGGTGGGGTGCCCCCATCAGCCCCGCTGCTCAGGGCCACTCATGGACTCTAGGAGGGTCCAGGTTCTGGGCTTCCT GGGAAGGTCCCCAGAAGAGAGAGGTGCTGGTAGACTAGGGAATGTGCTGGCAACTTGACCCAGAAGCTGTGGTCCCCTTGGCCCCGGCTC CACGGCATCCGGGTACCAGCAGCAAGAGCCCAGGCCCCGGGCTGCACGTCAGCTCACAGCCCAGGAGAAAGCTGGCTGCTTCCCCTCCCT ATGCGTCTTTCCCCCGCTCCAATCATGTTCCATCTGGGATCTGAAATGGGCCAACTGTGGCTGCTTTGGGGGTGACACGCTCCTTCTCCA ACTCAGCTGGGCCCCGGGCATCCCCTGCCCTCCCCTGAGACCCAAAGGGGGTTGGCACCTGCTGTGACACCACCGTTGACCCCAGCCTGG GGGCCACAAGGTTGCTGAGTGGGGAGAACATGGACCCCAACTCTATGGCAAGCAAGATCGCAGAAGGGGGAGCATCATCCGCAAGGACTT CAGGTCTCCCTTGGCTGGAGATGAGGATCCACATTAAATGCTTGTAACACACCAGGCCACAGAAAGCTCGCTACACACACATGCTTCTCC CCACCCATGCTGACTCTCAGAGGCTGCTAAGGCAGAATTTATAGGAAATTGTTTTCAAGCCACCAGAGACCTGTCTGTACAACTGGAAAG >20972_20972_2_CYFIP1-FAM189A1_CYFIP1_chr15_23000243_ENST00000435939_FAM189A1_chr15_29674035_ENST00000261275_length(amino acids)=1238AA_BP=772 MVRTMAESLGSAELLRQLKSLGMERLLHAVNTFLRQSCTYLPLLTFGGKTSFVSLDVYGTEANCSATSCSFPKAAATWPRRQAPGPLGEL VRGPPDQGVAEQSFSHGLFEFGITNVPCIFSPPQMFPWIIQLYMVRTMLESLIADKSGSKKTLRSSLEGPTILDIEKFHRESFFYTHLIN FSETLQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEASMMEYVLYSLDLYNDSAHYALTRFNKQFLYDEIEAEVNL CFDQFVYKLADQIFAYYKVMAGSLLLDKRLRSECKNQGATIHLPPSNRYETLLKQRHVQLLGRSIDLNRLITQRVSAAMYKSLELAIGRF ESEDLTSIVELDGLLEINRMTHKLLSRYLTLDGFDAMFREANHNVSAPYGRITLHVFWELNYDFLPNYCYNGSTNRFVRTVLPFSQEFQR DKQPNAQPQYLHGSKALNLAYSSIYGSYRNFVGPPHFQVICRLLGYQGIAVVMEELLKVVKSLLQGTILQYVKTLMEVMPKICRLPRHEY GSPGILEFFHHQLKDIVEYAELKTVCFQNLREVGNAILFCLLIEQSLSLEEVCDLLHAAPFQNILPRVHVKEGERLDAKMKRLESKYAPL HLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRSFLDDPIWRGPLPSNGVMHVDECVEFHRLWSAMQFVYCIPVGTHEF TVEQCFGDGLHWAGCMIIVLLGQQRRFAVLDFCYHLLKVQKHDGKDEIIKNVVLLSGLIGVVSWKRPLSLVITFFMLLSAVCVMLNLAGS ILSCQNAQLVNSLEGCQLIKFDSVEVCVCCELQHQSSGCSNLGETLKLNPLQENCNAVRLTLKDLLFSVCALNVLSTIVCALATAMCCMQ MVSSDVLQMFLPQRSHPANPTCVTPHGTVLHQTLDFDEFIPPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYP AELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSSPSPDGPVGAPAPSEPALPPGHVSPEDP GMGSQVQPGPGRVSRSTSDPTLCTSSMAGDASSHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKTDQRPTPEPFPA -------------------------------------------------------------- >20972_20972_3_CYFIP1-FAM189A1_CYFIP1_chr15_23000243_ENST00000560848_FAM189A1_chr15_29674035_ENST00000261275_length(transcript)=8274nt_BP=3788nt AGTGACTCACTCGGCCAAGGAAACTCCCAGGGCCCGCCCAGGACCCCCAAGCCGCCGCGGACGCAGAATGTGGCTCAGCTGCCCCTGGTC CCATCCCAGGGCAGAGCTCCTCCTGAGTACCCTTGAGACTGGAGCAGATTCAGCAGAAGGCAGATTGCCCCCTCTCCCTGGAGCTGGCTC TGAAGCCCAGGATGGCGGCCCAGGTGACTCTGGAGGACGCGCTGTCCAACGTGGACCTCCTGGAGGAGCTGCCCCTGCCCGACCAGCAGC CCTGCATCGAGCCCCCGCCATCCTCGCTGCTCTACCAGCCAAATTTCAACACTAACTTTGAAGACAGAAATGCATTTGTTACTGGCATCG CAAGATACATTGAACAAGCCACCGTCCACTCTAGCATGAACGAGATGCTGGAGGAGGGCCAAGAATATGCTGTCATGCTGTACACCTGGA GGAGCTGCTCCCGGGCCATCCCACAGGTGAAATGTAACGAGCAGCCTAACAGAGTGGAAATCTACGAGAAAACCGTGGAGGTTCTGGAGC CTGAGGTCACAAAACTGATGAATTTCATGTACTTCCAGAGAAATGCCATTGAGCGTTTCTGCGGGGAAGTGAGGCGCCTGTGCCATGCCG AGAGGAGGAAGGACTTCGTGTCAGAAGCCTACCTGATCACACTGGGCAAATTCATCAACATGTTCGCTGTGCTGGACGAGCTGAAGAACA TGAAGTGCAGTGTGAAGAACGACCACTCAGCGTACAAGAGGGCCGCTCAGTTTTTACGTAAAATGGCAGATCCACAGTCCATCCAGGAAT CGCAGAATCTGTCCATGTTCCTGGCCAATCATAACAAGATCACACAGTCTCTGCAGCAGCAGCTCGAAGTGATTTCTGGCTACGAAGAGC TCCTGGCAGATATTGTGAATCTGTGTGTGGATTACTACGAGAACAGGATGTATTTGACGCCCAGTGAGAAACACATGCTTCTCAAAGTCA TGGGATTTGGTCTGTACCTGATGGATGGGAGTGTCAGTAACATCTATAAGTTGGATGCCAAGAAAAGAATAAACTTATCCAAAATCGACA AGTACTTCAAGCAACTCCAGGTGGTTCCGCTATTTGGGGACATGCAAATAGAACTGGCAAGATATATCAAGACCAGCGCCCACTACGAGG AAAATAAATCTCGATGGACGTGCACATCCTCCGGCAGCAGCCCTCAGTACAACATCTGCGAGCAGATGATCCAGATCCGCGAGGACCACA TGCGCTTCATTTCGGAGCTGGCGCGCTACAGCAACAGCGAGGTGGTCACGGGCTCGGGCCGCCAGGAGGCCCAGAAGACGGACGCGGAGT ACCGCAAGCTCTTCGACCTGGCGCTGCAGGGCCTGCAGCTGTTGTCGCAGTGGAGCGCGCACGTGATGGAAGTGTATTCCTGGAAGCTTG TGCACCCCACCGACAAGTACTCCAACAAGGACTGCCCCGACAGCGCTGAAGAGTACGAGCGTGCCACGCGCTACAACTACACCAGCGAGG AGAAGTTTGCCCTAGTGGAGGTGATCGCCATGATCAAAGGCCTGCAGGTGCTGATGGGCAGGATGGAGAGCGTGTTCAACCACGCCATCC GGCACACCGTCTATGCCGCACTGCAGGACTTCTCCCAGGTGACCCTTAGGGAGCCGCTGCGGCAGGCCATCAAGAAGAAGAAGAACGTCA TCCAGAGTGTCCTGCAGGCCATCAGGAAGACCGTGTGTGACTGGGAGACGGGGCATGAGCCCTTCAATGACCCAGCCTTGCGGGGCGAGA AGGACCCCAAGAGCGGCTTCGACATAAAAGTACCACGCCGCGCCGTGGGACCCTCCAGCACTCAGCTTTACATGGTGAGAACCATGCTAG AGTCCCTCATTGCAGACAAAAGTGGTTCCAAGAAAACCTTGAGAAGTAGCCTTGAGGGGCCCACCATATTGGACATAGAAAAATTTCATC GAGAGTCATTCTTCTACACTCACTTGATAAATTTCAGTGAAACGCTGCAGCAGTGCTGTGACCTTTCGCAGCTGTGGTTCCGAGAGTTCT TCCTGGAGCTGACCATGGGCAGGAGGATCCAGTTCCCCATTGAGATGTCGATGCCCTGGATCCTGACGGACCACATCCTGGAGACCAAGG AGGCATCGATGATGGAGTACGTGCTCTACTCCCTGGACCTGTACAATGACAGCGCCCACTACGCGCTCACCAGGTTCAACAAGCAGTTCC TGTACGACGAAATTGAGGCCGAGGTGAATCTATGTTTTGACCAATTTGTTTACAAGCTAGCAGACCAGATATTTGCCTATTATAAGGTTA TGGCAGGAAGTTTGCTTCTTGATAAACGGTTACGATCAGAATGCAAGAATCAGGGAGCCACGATCCACCTCCCGCCGTCTAACCGCTACG AGACGCTGCTGAAGCAGAGGCATGTGCAGCTCCTCGGCAGATCAATAGACCTCAATCGTCTGATCACCCAGCGCGTCTCAGCAGCCATGT ATAAGTCCCTAGAACTGGCGATTGGACGATTTGAAAGTGAAGATTTGACCTCCATAGTTGAGCTGGATGGCCTGTTGGAAATCAACCGCA TGACCCACAAGCTGCTGAGCCGGTACCTGACGCTGGACGGCTTCGACGCCATGTTCCGGGAGGCCAACCACAACGTGTCAGCGCCCTACG GGAGGATCACCCTGCACGTCTTCTGGGAGCTCAACTATGACTTCCTGCCCAACTACTGCTACAACGGCTCTACCAACCGGTTTGTTCGGA CAGTGTTACCATTTTCTCAGGAATTTCAAAGAGATAAGCAGCCTAATGCACAGCCTCAGTATCTGCATGGATCCAAGGCTTTGAACTTGG CCTACTCCAGCATTTACGGCAGCTACCGGAACTTCGTGGGACCTCCACACTTTCAAGTCATCTGCCGGCTTCTCGGCTACCAGGGTATCG CCGTGGTCATGGAGGAGCTGCTGAAGGTCGTCAAGAGCCTGCTGCAAGGCACAATCCTGCAGTACGTGAAGACGCTGATGGAGGTGATGC CCAAGATCTGCCGCCTGCCCCGGCACGAGTACGGCTCTCCTGGTATCCTGGAGTTCTTCCACCACCAGCTGAAGGACATCGTGGAGTACG CAGAGCTGAAGACGGTGTGCTTCCAGAACCTGCGGGAGGTGGGGAACGCCATCCTCTTCTGCCTGCTCATCGAGCAGAGCCTGTCTTTAG AAGAAGTGTGTGACCTGCTGCACGCGGCTCCTTTCCAGAACATCTTGCCGCGAGTCCATGTGAAAGAGGGGGAGAGACTTGATGCCAAAA TGAAAAGACTAGAATCAAAGTACGCCCCGCTGCATCTTGTCCCACTGATTGAAAGACTGGGGACCCCTCAGCAAATTGCCATCGCAAGAG AGGGGGACCTGCTGACAAAGGAGCGCCTCTGCTGCGGCCTGTCCATGTTTGAGGTCATCCTGACACGGATCCGGAGCTTTCTGGATGACC CCATCTGGCGCGGGCCTCTGCCCAGCAATGGGGTCATGCATGTGGACGAGTGTGTGGAGTTTCACAGACTGTGGAGTGCCATGCAGTTTG TCTACTGCATTCCCGTGGGGACACACGAGTTCACAGTCGAGCAGTGCTTTGGTGATGGGCTACACTGGGCTGGCTGTATGATCATCGTAC TTCTTGGGCAGCAGCGGCGTTTTGCTGTGCTGGATTTCTGCTACCATCTACTTAAAGTCCAGAAACATGATGGCAAAGATGAGATTATTA AAAATGTGGTGCTGCTGTCGGGACTCATAGGTGTCGTCTCCTGGAAGAGGCCTCTCTCCCTTGTGATAACCTTTTTCATGCTGCTTTCTG CAGTGTGTGTAATGCTGAATTTGGCTGGTTCAATTCTCTCTTGTCAGAATGCTCAGCTAGTCAACTCCCTAGAAGGCTGCCAGTTGATTA AGTTTGACAGTGTGGAGGTGTGTGTCTGCTGTGAGCTGCAGCACCAGTCGTCCGGCTGCAGCAACCTCGGGGAGACGCTGAAGCTGAACC CGCTGCAGGAGAACTGCAACGCTGTGAGGCTGACCTTGAAGGATCTCCTCTTCAGCGTGTGTGCCCTCAACGTCCTGTCCACTATCGTGT GTGCGCTGGCCACAGCCATGTGCTGTATGCAGATGGTCTCCTCCGATGTCCTGCAGATGTTCCTTCCGCAGAGGTCACATCCTGCCAACC CCACCTGCGTGACTCCTCACGGCACCGTTCTCCACCAGACCCTGGATTTCGACGAGTTCATCCCCCCACTCCCGCCTCCACCCTATTACC CCCCAGAGTACACCTGCACACCGTCCACTGAGGCCCAGAGGGGCCTCCACCTGGACTTTGCTCCGTCTCCATTCGGCACTTTGTATGACG TGGCCATCAATAGCCCCGGCCTGCTCTATCCTGCTGAGCTCCCCCCTCCGTACGAGGCGGTGGTGGGCCAGCCCCCTGCCAGCCAGGTTA CAAGTATAGGTCAGCAGGTGGCCGAGTCCAGCTCCGGGGACCCAAACACCAGTGCTGGCTTCAGCACTCCAGTACCAGCTGACAGCACAA GCCTCCTGGTGTCCGAGGGCACTGCTACGCCAGGTTCCAGCCCATCCCCCGATGGCCCTGTGGGCGCCCCAGCACCCTCCGAACCTGCCC TTCCCCCTGGCCATGTGTCTCCAGAGGATCCTGGCATGGGCTCACAGGTGCAGCCAGGTCCCGGGCGTGTGTCCCGCTCCACCAGCGACC CCACCTTGTGCACATCTAGCATGGCAGGCGATGCCTCTTCACACAGGCCGTCGTGTAGCCAGGACCTGGAAGCGGGACTGTCTGAGGCTG TGCCTGGGAGCGCTTCCATGTCTCGCTCTGCCACGGCTGCCTGTCGGGCCCAGCTTTCACCAGCGGGGGACCCAGATACCTGGAAAACTG ACCAACGGCCAACACCAGAGCCCTTCCCAGCGACCTCCAAAGAGCGGCCACGCTCTTTAGTGGACAGCAAGGCCTATGCGGATGCCAGGG TTTTGGTGGCCAAGTTTTTGGAACACTCACACTGTGCCCTCCCCACCGAGGCACAGCACATGGTGGGTGCCATGCGCTTGGCTGTCACCA ACGAGGAGCGCCTCGAGGAGGAGGCCGTCTTCGGCGCTGACGTTCTGGACCAGGTATGAAGGAGCCACATTTCTGACCGTGGACACCAAC GCCTGGCGCCACAGATGTTCTTGGCAGAAGCCATCATGCCTGACAAAGAGGCCTTCAGGCCCAGCTTGGCGGAGGATAAATGTGGGGGGG ACACCCAGGATGATCTGGGGGCGGTGTGGGCAGGGAACTGTTACCCCCTCTCTCGAGGGGAGCCGAGCAGTGTCTCTTTGGGGATTGCAT TTCCTGCCTAGCCCAGTAATTCGGAAAGATGACTTTCACGTCCACAGTGAACTCTCTGGTTTTATCTGGCGTGCAGCACCTTGAACTGAG CAGTGTTGCACAAATGTGAATACAGCAACAGGCGACACTTACGTCACCTAAAGACTCAAAGTATCTCCAAAATCAGGGCCTTCCAAAGCA GGAGTCTCCCATCCCCCATTTAACTTAGTGTTCAGTGGACAGAGGGTGACATCGAGTCATGAAACATTTTCTCATGTGGCTCGATGGCTC TATCATTAGGCGTTCATCACGCTCTGGCCTATTTCCTGTGAAAGGAAATAGGTAGTGTTAGCACAGATGGCAGCCTGGGCCCAACTTTCT GTCCACAGGGCTATTGTGCAAACAAATGTGCAGTGCGGGCCTCTGCCATAGCCCGGCCCCCCCCAGGGAACAGGCCGGTGTTGCGGGGGT TGGAGGAACCCACCATCTCCTGGGCCTTGAGCTCGGCCTCCCTCCGTGGGGTGCCTTCCCCCCCTCCTCTTGGGCCCCCTTTCTCCAGGC TCCCATCCTGTCCCTGGAGCAGTTGTGTGATCCGTAACAACAAGTGCCGATTCCCAGCTCCTTTGTGTCTGAGCTCACTTGATTGAGCTC AGCGGGTCACAGTTCTGCAGGAGAGAGGCCGGTTTCTCTGAGAAGTAGCCCCTCCTGATAAAGCAGGTCCCTTTGACCCAGAGCTGACCT TTCCCCGGGCATGCGGCAGCAGACACACCTGCGCAGGAGGATCATAAACCACTTACAAACCCACACGAGAAGGGAAGCAGACACCCAACG TGCTGCTTATGGAGAAGCAGACACGCCCAGCTTGGGGACAGCCTGGGGACCTTGGACTTTCTTAGCCCCCATCCCCTTGTTTTCTGGTGG CATCAGTGGCAGCTGCTCCCAACAATGGCCGTGGAACAGCGCCATCCACGAGAACTTTGTGCAGTGATGGAAATGCCTGTTCAGGGCCAC TAGCAGCCACAGCCCCTGAGCTGCGTTGGGTGGGCCCTGCGGTGAACAAAACAGCCTAGAGGCCAAGGTCTCCCCAGAGAGCCCATGAGC CTGGCATGGGGGCGCAGGGGGACCAGAGGGTGTCTTCCACTCCTGGGTGCCAGGGCAGGGGGCTCACGCTGCTGTTCCCTCGGCTTTGTG GGGCTTGTCCTTGAGCTCCCCCAATTCCCTAATGCCACTGTGGCCAGTGTGCTGGGGAGCTTCTGTGTGGCTGGAAGCTGGGAAGGGGGT GAGGTTCCAATCCAGGTGCCCAGAGCCTTCCTCCAGTCCTTTATCCCTGCCCTGGGGGCTGCGGTGTGGGACTCCTTCAGCTGTGGTCGG CTGAAAAGGCTTCGATTGCTTTAGAGAGCTGAAAACACATAAGCCAGGCCTTTTGATGACAACCTGCACTTTTGCAGGAGAGACGTACTA GAGATGAATTTTTGAGCACTTTATTCAGACTATAAAACAGGAAATCTCTAATTTTCCTCAAGTGGGGGCTTTTGAATTCCCTCAAGGCAA GTCCCTTTGCAGGTGAAATTAATTGGTGGATTTTCAGAATGGCCGCCCTGGAGCCGAGCTTCAGCCACGCCTGACGCCCTGGCCTCTGAA TCTCCACTGTCTCTGAGGTGCGCTGGGGCCACGCCGCAGGGGTTTCACCTGCTTGGGGGGGTCCACACTAGGGCTTGGGGGTTCACACAG CATTGTCCCTGGGCTGAGCCCTTGGGTGGGCTAGAGCTGCAGTCCTCAGACATGGCTGCAATTCCAGCGAGGCCAAGACCACCAGCCACC CAGTGGACTCGGTCTCTGGGGTGTTCTCCTCATGCAGCCGGGGCAGAGGCCTACTGGACCCCCTCAGCCTGCTGCTCAGCATCCTTCCCT TCTCTGCAGCAGGGCCCGGTCCCAATGGCCAATGGGGCTGCTGCCCCAGCAGTGCCTCCCTGTAGGCCCCTCACCTGCACCCCACCTTCA CCCAGCTCTGGGTTTGCGCTGGTGGCAGCTCTGTTTTGTGGATACGGAAACTGTACCCAACTTGATGCCGCTGGGCTGGAACCTTCTGCC CCTTCGAAATGAGGCAGTCAGGGACGGGGTGGGGTGCCCCCATCAGCCCCGCTGCTCAGGGCCACTCATGGACTCTAGGAGGGTCCAGGT TCTGGGCTTCCTGGGAAGGTCCCCAGAAGAGAGAGGTGCTGGTAGACTAGGGAATGTGCTGGCAACTTGACCCAGAAGCTGTGGTCCCCT TGGCCCCGGCTCCACGGCATCCGGGTACCAGCAGCAAGAGCCCAGGCCCCGGGCTGCACGTCAGCTCACAGCCCAGGAGAAAGCTGGCTG CTTCCCCTCCCTATGCGTCTTTCCCCCGCTCCAATCATGTTCCATCTGGGATCTGAAATGGGCCAACTGTGGCTGCTTTGGGGGTGACAC GCTCCTTCTCCAACTCAGCTGGGCCCCGGGCATCCCCTGCCCTCCCCTGAGACCCAAAGGGGGTTGGCACCTGCTGTGACACCACCGTTG ACCCCAGCCTGGGGGCCACAAGGTTGCTGAGTGGGGAGAACATGGACCCCAACTCTATGGCAAGCAAGATCGCAGAAGGGGGAGCATCAT CCGCAAGGACTTCAGGTCTCCCTTGGCTGGAGATGAGGATCCACATTAAATGCTTGTAACACACCAGGCCACAGAAAGCTCGCTACACAC ACATGCTTCTCCCCACCCATGCTGACTCTCAGAGGCTGCTAAGGCAGAATTTATAGGAAATTGTTTTCAAGCCACCAGAGACCTGTCTGT >20972_20972_3_CYFIP1-FAM189A1_CYFIP1_chr15_23000243_ENST00000560848_FAM189A1_chr15_29674035_ENST00000261275_length(amino acids)=1688AA_BP=1222 MRLEQIQQKADCPLSLELALKPRMAAQVTLEDALSNVDLLEELPLPDQQPCIEPPPSSLLYQPNFNTNFEDRNAFVTGIARYIEQATVHS SMNEMLEEGQEYAVMLYTWRSCSRAIPQVKCNEQPNRVEIYEKTVEVLEPEVTKLMNFMYFQRNAIERFCGEVRRLCHAERRKDFVSEAY LITLGKFINMFAVLDELKNMKCSVKNDHSAYKRAAQFLRKMADPQSIQESQNLSMFLANHNKITQSLQQQLEVISGYEELLADIVNLCVD YYENRMYLTPSEKHMLLKVMGFGLYLMDGSVSNIYKLDAKKRINLSKIDKYFKQLQVVPLFGDMQIELARYIKTSAHYEENKSRWTCTSS GSSPQYNICEQMIQIREDHMRFISELARYSNSEVVTGSGRQEAQKTDAEYRKLFDLALQGLQLLSQWSAHVMEVYSWKLVHPTDKYSNKD CPDSAEEYERATRYNYTSEEKFALVEVIAMIKGLQVLMGRMESVFNHAIRHTVYAALQDFSQVTLREPLRQAIKKKKNVIQSVLQAIRKT VCDWETGHEPFNDPALRGEKDPKSGFDIKVPRRAVGPSSTQLYMVRTMLESLIADKSGSKKTLRSSLEGPTILDIEKFHRESFFYTHLIN FSETLQQCCDLSQLWFREFFLELTMGRRIQFPIEMSMPWILTDHILETKEASMMEYVLYSLDLYNDSAHYALTRFNKQFLYDEIEAEVNL CFDQFVYKLADQIFAYYKVMAGSLLLDKRLRSECKNQGATIHLPPSNRYETLLKQRHVQLLGRSIDLNRLITQRVSAAMYKSLELAIGRF ESEDLTSIVELDGLLEINRMTHKLLSRYLTLDGFDAMFREANHNVSAPYGRITLHVFWELNYDFLPNYCYNGSTNRFVRTVLPFSQEFQR DKQPNAQPQYLHGSKALNLAYSSIYGSYRNFVGPPHFQVICRLLGYQGIAVVMEELLKVVKSLLQGTILQYVKTLMEVMPKICRLPRHEY GSPGILEFFHHQLKDIVEYAELKTVCFQNLREVGNAILFCLLIEQSLSLEEVCDLLHAAPFQNILPRVHVKEGERLDAKMKRLESKYAPL HLVPLIERLGTPQQIAIAREGDLLTKERLCCGLSMFEVILTRIRSFLDDPIWRGPLPSNGVMHVDECVEFHRLWSAMQFVYCIPVGTHEF TVEQCFGDGLHWAGCMIIVLLGQQRRFAVLDFCYHLLKVQKHDGKDEIIKNVVLLSGLIGVVSWKRPLSLVITFFMLLSAVCVMLNLAGS ILSCQNAQLVNSLEGCQLIKFDSVEVCVCCELQHQSSGCSNLGETLKLNPLQENCNAVRLTLKDLLFSVCALNVLSTIVCALATAMCCMQ MVSSDVLQMFLPQRSHPANPTCVTPHGTVLHQTLDFDEFIPPLPPPPYYPPEYTCTPSTEAQRGLHLDFAPSPFGTLYDVAINSPGLLYP AELPPPYEAVVGQPPASQVTSIGQQVAESSSGDPNTSAGFSTPVPADSTSLLVSEGTATPGSSPSPDGPVGAPAPSEPALPPGHVSPEDP GMGSQVQPGPGRVSRSTSDPTLCTSSMAGDASSHRPSCSQDLEAGLSEAVPGSASMSRSATAACRAQLSPAGDPDTWKTDQRPTPEPFPA -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for CYFIP1-FAM189A1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for CYFIP1-FAM189A1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for CYFIP1-FAM189A1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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