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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:CYP2E1-GLUL (FusionGDB2 ID:21058)

Fusion Gene Summary for CYP2E1-GLUL

check button Fusion gene summary
Fusion gene informationFusion gene name: CYP2E1-GLUL
Fusion gene ID: 21058
HgeneTgene
Gene symbol

CYP2E1

GLUL

Gene ID

1571

2752

Gene namecytochrome P450 family 2 subfamily E member 1glutamate-ammonia ligase
SynonymsCPE1|CYP2E|P450-J|P450C2EGLNS|GS|PIG43|PIG59
Cytomap

10q26.3

1q25.3

Type of geneprotein-codingprotein-coding
Descriptioncytochrome P450 2E14-nitrophenol 2-hydroxylaseCYPIIE1cytochrome P450, family 2, subfamily E, polypeptide 1cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1cytochrome P450-Jflavoprotein-linked monooxygenasemicrosomal monooxygenasexeglutamine synthetasecell proliferation-inducing protein 59glutamate decarboxylaseglutamine synthasepalmitoyltransferase GLULproliferation-inducing protein 43
Modification date2020031520200313
UniProtAcc

P05181

P15104

Ensembl transtripts involved in fusion geneENST00000252945, ENST00000463117, 
ENST00000480558, 		ENST00000339526, 
ENST00000491322, ENST00000311223, 
ENST00000331872, ENST00000417584, 
Fusion gene scores* DoF score8 X 5 X 3=12018 X 16 X 6=1728
# samples 820
** MAII scorelog2(8/120*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(20/1728*10)=-3.11103131238874
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: CYP2E1 [Title/Abstract] AND GLUL [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCYP2E1(135345788)-GLUL(182354691), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneCYP2E1

GO:0002933

lipid hydroxylation

10553002

HgeneCYP2E1

GO:0016098

monoterpenoid metabolic process

16401082

HgeneCYP2E1

GO:0017144

drug metabolic process

19219744

HgeneCYP2E1

GO:0018960

4-nitrophenol metabolic process

9348445

HgeneCYP2E1

GO:0046483

heterocycle metabolic process

19651758

HgeneCYP2E1

GO:0055114

oxidation-reduction process

16401082|19219744

TgeneGLUL

GO:0008283

cell proliferation

18662667

TgeneGLUL

GO:0010594

regulation of endothelial cell migration

30158707

TgeneGLUL

GO:0018345

protein palmitoylation

30158707

TgeneGLUL

GO:1903670

regulation of sprouting angiogenesis

30158707


check buttonFusion gene breakpoints across CYP2E1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across GLUL (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LIHCTCGA-UB-A7MC-01ACYP2E1chr10

135345788

+GLULchr1

182354691

-


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Fusion Gene ORF analysis for CYP2E1-GLUL

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000252945ENST00000339526CYP2E1chr10

135345788

+GLULchr1

182354691

-
5CDS-5UTRENST00000252945ENST00000491322CYP2E1chr10

135345788

+GLULchr1

182354691

-
5CDS-5UTRENST00000463117ENST00000339526CYP2E1chr10

135345788

+GLULchr1

182354691

-
5CDS-5UTRENST00000463117ENST00000491322CYP2E1chr10

135345788

+GLULchr1

182354691

-
In-frameENST00000252945ENST00000311223CYP2E1chr10

135345788

+GLULchr1

182354691

-
In-frameENST00000252945ENST00000331872CYP2E1chr10

135345788

+GLULchr1

182354691

-
In-frameENST00000252945ENST00000417584CYP2E1chr10

135345788

+GLULchr1

182354691

-
In-frameENST00000463117ENST00000311223CYP2E1chr10

135345788

+GLULchr1

182354691

-
In-frameENST00000463117ENST00000331872CYP2E1chr10

135345788

+GLULchr1

182354691

-
In-frameENST00000463117ENST00000417584CYP2E1chr10

135345788

+GLULchr1

182354691

-
intron-3CDSENST00000480558ENST00000311223CYP2E1chr10

135345788

+GLULchr1

182354691

-
intron-3CDSENST00000480558ENST00000331872CYP2E1chr10

135345788

+GLULchr1

182354691

-
intron-3CDSENST00000480558ENST00000417584CYP2E1chr10

135345788

+GLULchr1

182354691

-
intron-5UTRENST00000480558ENST00000339526CYP2E1chr10

135345788

+GLULchr1

182354691

-
intron-5UTRENST00000480558ENST00000491322CYP2E1chr10

135345788

+GLULchr1

182354691

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000463117CYP2E1chr10135345788+ENST00000331872GLULchr1182354691-41409202001438412
ENST00000463117CYP2E1chr10135345788+ENST00000417584GLULchr1182354691-41399202001438412
ENST00000463117CYP2E1chr10135345788+ENST00000311223GLULchr1182354691-41399202001438412
ENST00000252945CYP2E1chr10135345788+ENST00000331872GLULchr1182354691-3901681331199388
ENST00000252945CYP2E1chr10135345788+ENST00000417584GLULchr1182354691-3900681331199388
ENST00000252945CYP2E1chr10135345788+ENST00000311223GLULchr1182354691-3900681331199388

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000463117ENST00000331872CYP2E1chr10135345788+GLULchr1182354691-0.0002726750.9997273
ENST00000463117ENST00000417584CYP2E1chr10135345788+GLULchr1182354691-0.0002719830.999728
ENST00000463117ENST00000311223CYP2E1chr10135345788+GLULchr1182354691-0.0002719830.999728
ENST00000252945ENST00000331872CYP2E1chr10135345788+GLULchr1182354691-0.0002554180.9997446
ENST00000252945ENST00000417584CYP2E1chr10135345788+GLULchr1182354691-0.0002550140.99974495
ENST00000252945ENST00000311223CYP2E1chr10135345788+GLULchr1182354691-0.0002550140.99974495

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Fusion Genomic Features for CYP2E1-GLUL


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for CYP2E1-GLUL


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:135345788/chr1:182354691)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
CYP2E1

P05181

GLUL

P15104

FUNCTION: A cytochrome P450 monooxygenase involved in the metabolism of fatty acids (PubMed:10553002, PubMed:18577768). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase) (PubMed:10553002, PubMed:18577768). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids (PubMed:10553002, PubMed:18577768). May be involved in the oxidative metabolism of xenobiotics (Probable). {ECO:0000269|PubMed:10553002, ECO:0000269|PubMed:18577768, ECO:0000305|PubMed:9348445}.FUNCTION: Glutamine synthetase that catalyzes the ATP-dependent conversion of glutamate and ammonia to glutamine (PubMed:30158707, PubMed:16267323). Its role depends on tissue localization: in the brain, it regulates the levels of toxic ammonia and converts neurotoxic glutamate to harmless glutamine, whereas in the liver, it is one of the enzymes responsible for the removal of ammonia (By similarity). Essential for proliferation of fetal skin fibroblasts (PubMed:18662667). Independently of its glutamine synthetase activity, required for endothelial cell migration during vascular development: acts by regulating membrane localization and activation of the GTPase RHOJ, possibly by promoting RHOJ palmitoylation (PubMed:30158707). May act as a palmitoyltransferase for RHOJ: able to autopalmitoylate and then transfer the palmitoyl group to RHOJ (PubMed:30158707). Plays a role in ribosomal 40S subunit biogenesis (PubMed:26711351). {ECO:0000250|UniProtKB:P15105, ECO:0000269|PubMed:16267323, ECO:0000269|PubMed:18662667, ECO:0000269|PubMed:26711351, ECO:0000269|PubMed:30158707}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneGLULchr10:135345788chr1:182354691ENST0000031122358203_208201374.0Nucleotide bindingATP
TgeneGLULchr10:135345788chr1:182354691ENST0000031122358255_257201374.0Nucleotide bindingATP
TgeneGLULchr10:135345788chr1:182354691ENST0000031122358336_338201374.0Nucleotide bindingADP
TgeneGLULchr10:135345788chr1:182354691ENST0000033187247203_208201374.0Nucleotide bindingATP
TgeneGLULchr10:135345788chr1:182354691ENST0000033187247255_257201374.0Nucleotide bindingATP
TgeneGLULchr10:135345788chr1:182354691ENST0000033187247336_338201374.0Nucleotide bindingADP
TgeneGLULchr10:135345788chr1:182354691ENST0000033952647203_208201374.0Nucleotide bindingATP
TgeneGLULchr10:135345788chr1:182354691ENST0000033952647255_257201374.0Nucleotide bindingATP
TgeneGLULchr10:135345788chr1:182354691ENST0000033952647336_338201374.0Nucleotide bindingADP
TgeneGLULchr10:135345788chr1:182354691ENST0000041758447203_208201374.0Nucleotide bindingATP
TgeneGLULchr10:135345788chr1:182354691ENST0000041758447255_257201374.0Nucleotide bindingATP
TgeneGLULchr10:135345788chr1:182354691ENST0000041758447336_338201374.0Nucleotide bindingADP
TgeneGLULchr10:135345788chr1:182354691ENST0000031122358246_247201374.0RegionL-glutamate binding
TgeneGLULchr10:135345788chr1:182354691ENST0000033187247246_247201374.0RegionL-glutamate binding
TgeneGLULchr10:135345788chr1:182354691ENST0000033952647246_247201374.0RegionL-glutamate binding
TgeneGLULchr10:135345788chr1:182354691ENST0000041758447246_247201374.0RegionL-glutamate binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneCYP2E1chr10:135345788chr1:182354691ENST00000252945+49298_303216494.0RegionSubstrate binding
HgeneCYP2E1chr10:135345788chr1:182354691ENST00000463117+611298_303216494.0RegionSubstrate binding


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Fusion Gene Sequence for CYP2E1-GLUL


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>21058_21058_1_CYP2E1-GLUL_CYP2E1_chr10_135345788_ENST00000252945_GLUL_chr1_182354691_ENST00000311223_length(transcript)=3900nt_BP=681nt
CTCCCGGGCTGGCAGCAGGGCCCCAGCGGCACCATGTCTGCCCTCGGAGTCACCGTGGCCCTGCTGGTGTGGGCGGCCTTCCTCCTGCTG
GTGTCCATGTGGAGGCAGGTGCACAGCAGCTGGAATCTGCCCCCAGGCCCTTTCCCGCTTCCCATCATCGGGAACCTCTTCCAGTTGGAA
TTGAAGAATATTCCCAAGTCCTTCACCCGGTTGGCCCAGCGCTTCGGGCCGGTGTTCACGCTGTACGTGGGCTCGCAGCGCATGGTGGTG
ATGCACGGCTACAAGGCGGTGAAGGAAGCGCTGCTGGACTACAAGGACGAGTTCTCGGGCAGAGGCGACCTCCCCGCGTTCCATGCGCAC
AGGGACAGGGGAATCATTTTTAATAATGGACCTACCTGGAAGGACATCCGGCGGTTTTCCCTGACCACCCTCCGGAACTATGGGATGGGG
AAACAGGGCAATGAGAGCCGGATCCAGAGGGAGGCCCACTTCCTGCTGGAAGCACTCAGGAAGACCCAAGGCCAGCCTTTCGACCCCACC
TTCCTCATCGGCTGCGCGCCCTGCAACGTCATAGCCGACATCCTCTTCCGCAAGCATTTTGACTACAATGATGAGAAGTTTCTAAGGCTG
ATGTATTTGTTTAATGAGAACTTCCACCTACTCAGCACTCCCTGGCTCCAGTGGGAATTTCAGATTGGACCTTGTGAAGGAATCAGCATG
GGAGATCATCTCTGGGTGGCCCGTTTCATCTTGCATCGTGTGTGTGAAGACTTTGGAGTGATAGCAACCTTTGATCCTAAGCCCATTCCT
GGGAACTGGAATGGTGCAGGCTGCCATACCAACTTCAGCACCAAGGCCATGCGGGAGGAGAATGGTCTGAAGTACATCGAGGAGGCCATT
GAGAAACTAAGCAAGCGGCACCAGTACCACATCCGTGCCTATGATCCCAAGGGAGGCCTGGACAATGCCCGACGTCTAACTGGATTCCAT
GAAACCTCCAACATCAACGACTTTTCTGCTGGTGTAGCCAATCGTAGCGCCAGCATACGCATTCCCCGGACTGTTGGCCAGGAGAAGAAG
GGTTACTTTGAAGATCGTCGCCCCTCTGCCAACTGCGACCCCTTTTCGGTGACAGAAGCCCTCATCCGCACGTGTCTTCTCAATGAAACC
GGCGATGAGCCCTTCCAGTACAAAAATTAAGTGGACTAGACCTCCAGCTGTTGAGCCCCTCCTAGTTCTTCATCCCACTCCAACTCTTCC
CCCTCTCCCAGTTGTCCCGATTGTAACTCAAAGGGTGGAATATCAAGGTCGTTTTTTTCATTCCATGTGCCCAGTTAATCTTGCTTTCTT
TGTTTGGCTGGGATAGAGGGGTCAAGTTATTAATTTCTTCACACCTACCCTCCTTTTTTTCCCTATCACTGAAGCTTTTTAGTGCATTAG
TGGGGAGGAGGGTGGGGAGACATAACCACTGCTTCCATTTAATGGGGTGCACCTGTCCAATAGGCGTAGCTATCCGGACAGAGCACGTTT
GCAGAAGGGGGTCTCTTCTTCCAGGTAGCTGAAAGGGGAAGACCTGACGTACTCTGGTTAGGTTAGGACTTGCCCTCGTGGTGGAAACTT
TTCTTAAAAAGTTATAACCAACTTTTCTATTAAAAGTGGGAATTAGGAGAGAAGGTAGGGGTTGGGAATCAGAGAGAATGGCTTTGGTCT
CTTGCTTGTGGGACTAGCCTGGCTTGGGACTAAATGCCCTGCTCTGAACACGAAGCTTAGTATAAACTGATGGATATCCCTACCTTGAAA
GAAGAAAAGGTTCTTACTGCTTGGTCCTTGATTTATCACACAAAGCAGAATAGTATTTTTATATTTAAATGTAAAGACAAAAAACTATAT
GTATGGTTTTGTGGATTATGTGTGTTTTGCTAAAGGAAAAAACCATCCAGGTCACGGGGCACCAAATTTGAGACAAATAGTCGGATTAGA
AATAAAGCATCTCATTTTGAGTAGAGAGCAAGGGAAGTGGTTCTTAGATGGTGATCTGGGATTAGGCCCTCAAGACCCTTTTGGGTTTCT
GCCCTGCCCACCCTCTGGAGAAGGTGGGCACTGGATTAGTTAACAGACAACACGTTACTAGCAGTCACTTGATCTCCGTGGCTTTGGTTT
AAAAGACACACTTGTCCACATAGGTTTAGAGATAAGAGTTGGCTGGTCAACTTGAGCATGTTACTGACAGAGGGGGTATTGGGGTTATTT
TCTGGTAGGAATAGCATGTCACTAAAGCAGGCCTTTTGATATTAAATTTTTTAAAAAGCAAAATTATAGAAGTTTAGATTTTAATCAAAT
TTGTAGGGTTTCTAGGTAATTTTTACAGAATTGCTTGTTTGCTTCAACTGTCTCCTACCTCTGCTCTTGGAGGAGATGGGGACAGGGCTG
GAGTCAAAACACTTGTAATTTTGTATCTTGATGTCTTTGTTAAGACTGCTGAAGAATTATTTTTTTTCTTTTATAATAAGGAATAAACCC
CACCTTTATTCCTTCATTTCATCTACCATTTTCTGGTTCTTGTGTTGGCTGTGGCAGGCCAGCTGTGGTTTTCTTTTGCCATGACAACTT
CTAATTGCCATGTACAGTATGTTCAAAGTCAAATAACTCCTCATTGTAAACAAACTGTGTAACTGCCCAAAGCAGCACTTATAAATCAGC
CTAACATAAGATCTCTCTGATGTGTTTGTGATTCTTTCAAATCCCTATGTGCCATTATATTTCTTTATTTCCTAAAACAGGCAAAATAAG
CTCAAGTTTATGTACTCTGAGTTTTTAAAACACTGGAGTGATGTTGCTGACCAGCCGTTTCCTGTACCTCTCTAAGTTGGGTATTTGGGA
CTTAAGGGATTAAGTTTTTCACCTAGACTTAGTTACACACAATCTTGGCATTTCCTAGCCTAGAGGTTTGTAGCAGGGTACAAGCCCCAC
TCCTCCCCCTTCCTTTGCTCCCCTGAGTTTGGTTTTGGCTTACCATAACATTGTTTTGACCATTCCTAGCCTAATACAATAGCCTAACAT
AATGTAAGATTAACTGGCTTTACGATTTCTATTCTCTGCTCTCAGTGATAAGAAACAAATATTAGCTACCCTGCTACCCTGGTTGAAGCC
TTCCAAGGCTGGCTATGCCCTAGGCATGGGCTCATCCTTGGGTGTATCTTGCCTTGCAGGAAGACCAGTGGACCGATTGTGATTCTCAAA
AGCTCTGTGTTGTCACCTGTGCCCTTGCCCCTTGCTCTTATCTTGGTCCGTGTATCTGGGAGTTCTTCCACCTTATCTTGGCCAATTCCT
ACCTTCGTTCATTCCTCATGAGGTTGGGTAAAAGCTCCCTCCGGCTCCCATGATGCTGTGCATATACCTAGCAAAAAGCAATTATTGGAC
ACATTGGAGTGCAATATTATTAATAGCATTAATACTACTAATAATGTGGGCAATAGTGATTGTTTTTAAAAGGCAGTATACTCTTACCAG
TGCGAGGTAGCTGGGGCCTGTGATAGTTTTTAGAGATAAGTTCTTCAGGCAACTGTGTATTTTACACTAGTCAAGTAATCCTAGATATCC
GTGGTTTTTCTTAAGAAAGTTGGCTCGTAATATGATTTAATATTCAAAGTAGAGTCATCTACCTATTAGCTTGCTGGCGTGGTCCTAGTT
TATGCCTGTTTCAGCATGATTGTTGAGTACCCTGTTTCATCCTTAGCATTTTCTTGATTTTGTTGTTAAATGATGTATACCCTTATTTCC
ATTGAATCTGTGCTTCCACCCCCCCAACTGAAGTTGTCTTCCCTTTGCTTGGCCACCCTTACAGCCTCTTGGATGGTGTATCCTACAGTG

>21058_21058_1_CYP2E1-GLUL_CYP2E1_chr10_135345788_ENST00000252945_GLUL_chr1_182354691_ENST00000311223_length(amino acids)=388AA_BP=198
MSALGVTVALLVWAAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVKEAL
LDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVI
ADILFRKHFDYNDEKFLRLMYLFNENFHLLSTPWLQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTN
FSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSAN

--------------------------------------------------------------
>21058_21058_2_CYP2E1-GLUL_CYP2E1_chr10_135345788_ENST00000252945_GLUL_chr1_182354691_ENST00000331872_length(transcript)=3901nt_BP=681nt
CTCCCGGGCTGGCAGCAGGGCCCCAGCGGCACCATGTCTGCCCTCGGAGTCACCGTGGCCCTGCTGGTGTGGGCGGCCTTCCTCCTGCTG
GTGTCCATGTGGAGGCAGGTGCACAGCAGCTGGAATCTGCCCCCAGGCCCTTTCCCGCTTCCCATCATCGGGAACCTCTTCCAGTTGGAA
TTGAAGAATATTCCCAAGTCCTTCACCCGGTTGGCCCAGCGCTTCGGGCCGGTGTTCACGCTGTACGTGGGCTCGCAGCGCATGGTGGTG
ATGCACGGCTACAAGGCGGTGAAGGAAGCGCTGCTGGACTACAAGGACGAGTTCTCGGGCAGAGGCGACCTCCCCGCGTTCCATGCGCAC
AGGGACAGGGGAATCATTTTTAATAATGGACCTACCTGGAAGGACATCCGGCGGTTTTCCCTGACCACCCTCCGGAACTATGGGATGGGG
AAACAGGGCAATGAGAGCCGGATCCAGAGGGAGGCCCACTTCCTGCTGGAAGCACTCAGGAAGACCCAAGGCCAGCCTTTCGACCCCACC
TTCCTCATCGGCTGCGCGCCCTGCAACGTCATAGCCGACATCCTCTTCCGCAAGCATTTTGACTACAATGATGAGAAGTTTCTAAGGCTG
ATGTATTTGTTTAATGAGAACTTCCACCTACTCAGCACTCCCTGGCTCCAGTGGGAATTTCAGATTGGACCTTGTGAAGGAATCAGCATG
GGAGATCATCTCTGGGTGGCCCGTTTCATCTTGCATCGTGTGTGTGAAGACTTTGGAGTGATAGCAACCTTTGATCCTAAGCCCATTCCT
GGGAACTGGAATGGTGCAGGCTGCCATACCAACTTCAGCACCAAGGCCATGCGGGAGGAGAATGGTCTGAAGTACATCGAGGAGGCCATT
GAGAAACTAAGCAAGCGGCACCAGTACCACATCCGTGCCTATGATCCCAAGGGAGGCCTGGACAATGCCCGACGTCTAACTGGATTCCAT
GAAACCTCCAACATCAACGACTTTTCTGCTGGTGTAGCCAATCGTAGCGCCAGCATACGCATTCCCCGGACTGTTGGCCAGGAGAAGAAG
GGTTACTTTGAAGATCGTCGCCCCTCTGCCAACTGCGACCCCTTTTCGGTGACAGAAGCCCTCATCCGCACGTGTCTTCTCAATGAAACC
GGCGATGAGCCCTTCCAGTACAAAAATTAAGTGGACTAGACCTCCAGCTGTTGAGCCCCTCCTAGTTCTTCATCCCACTCCAACTCTTCC
CCCTCTCCCAGTTGTCCCGATTGTAACTCAAAGGGTGGAATATCAAGGTCGTTTTTTTCATTCCATGTGCCCAGTTAATCTTGCTTTCTT
TGTTTGGCTGGGATAGAGGGGTCAAGTTATTAATTTCTTCACACCTACCCTCCTTTTTTTCCCTATCACTGAAGCTTTTTAGTGCATTAG
TGGGGAGGAGGGTGGGGAGACATAACCACTGCTTCCATTTAATGGGGTGCACCTGTCCAATAGGCGTAGCTATCCGGACAGAGCACGTTT
GCAGAAGGGGGTCTCTTCTTCCAGGTAGCTGAAAGGGGAAGACCTGACGTACTCTGGTTAGGTTAGGACTTGCCCTCGTGGTGGAAACTT
TTCTTAAAAAGTTATAACCAACTTTTCTATTAAAAGTGGGAATTAGGAGAGAAGGTAGGGGTTGGGAATCAGAGAGAATGGCTTTGGTCT
CTTGCTTGTGGGACTAGCCTGGCTTGGGACTAAATGCCCTGCTCTGAACACGAAGCTTAGTATAAACTGATGGATATCCCTACCTTGAAA
GAAGAAAAGGTTCTTACTGCTTGGTCCTTGATTTATCACACAAAGCAGAATAGTATTTTTATATTTAAATGTAAAGACAAAAAACTATAT
GTATGGTTTTGTGGATTATGTGTGTTTTGCTAAAGGAAAAAACCATCCAGGTCACGGGGCACCAAATTTGAGACAAATAGTCGGATTAGA
AATAAAGCATCTCATTTTGAGTAGAGAGCAAGGGAAGTGGTTCTTAGATGGTGATCTGGGATTAGGCCCTCAAGACCCTTTTGGGTTTCT
GCCCTGCCCACCCTCTGGAGAAGGTGGGCACTGGATTAGTTAACAGACAACACGTTACTAGCAGTCACTTGATCTCCGTGGCTTTGGTTT
AAAAGACACACTTGTCCACATAGGTTTAGAGATAAGAGTTGGCTGGTCAACTTGAGCATGTTACTGACAGAGGGGGTATTGGGGTTATTT
TCTGGTAGGAATAGCATGTCACTAAAGCAGGCCTTTTGATATTAAATTTTTTAAAAAGCAAAATTATAGAAGTTTAGATTTTAATCAAAT
TTGTAGGGTTTCTAGGTAATTTTTACAGAATTGCTTGTTTGCTTCAACTGTCTCCTACCTCTGCTCTTGGAGGAGATGGGGACAGGGCTG
GAGTCAAAACACTTGTAATTTTGTATCTTGATGTCTTTGTTAAGACTGCTGAAGAATTATTTTTTTTCTTTTATAATAAGGAATAAACCC
CACCTTTATTCCTTCATTTCATCTACCATTTTCTGGTTCTTGTGTTGGCTGTGGCAGGCCAGCTGTGGTTTTCTTTTGCCATGACAACTT
CTAATTGCCATGTACAGTATGTTCAAAGTCAAATAACTCCTCATTGTAAACAAACTGTGTAACTGCCCAAAGCAGCACTTATAAATCAGC
CTAACATAAGATCTCTCTGATGTGTTTGTGATTCTTTCAAATCCCTATGTGCCATTATATTTCTTTATTTCCTAAAACAGGCAAAATAAG
CTCAAGTTTATGTACTCTGAGTTTTTAAAACACTGGAGTGATGTTGCTGACCAGCCGTTTCCTGTACCTCTCTAAGTTGGGTATTTGGGA
CTTAAGGGATTAAGTTTTTCACCTAGACTTAGTTACACACAATCTTGGCATTTCCTAGCCTAGAGGTTTGTAGCAGGGTACAAGCCCCAC
TCCTCCCCCTTCCTTTGCTCCCCTGAGTTTGGTTTTGGCTTACCATAACATTGTTTTGACCATTCCTAGCCTAATACAATAGCCTAACAT
AATGTAAGATTAACTGGCTTTACGATTTCTATTCTCTGCTCTCAGTGATAAGAAACAAATATTAGCTACCCTGCTACCCTGGTTGAAGCC
TTCCAAGGCTGGCTATGCCCTAGGCATGGGCTCATCCTTGGGTGTATCTTGCCTTGCAGGAAGACCAGTGGACCGATTGTGATTCTCAAA
AGCTCTGTGTTGTCACCTGTGCCCTTGCCCCTTGCTCTTATCTTGGTCCGTGTATCTGGGAGTTCTTCCACCTTATCTTGGCCAATTCCT
ACCTTCGTTCATTCCTCATGAGGTTGGGTAAAAGCTCCCTCCGGCTCCCATGATGCTGTGCATATACCTAGCAAAAAGCAATTATTGGAC
ACATTGGAGTGCAATATTATTAATAGCATTAATACTACTAATAATGTGGGCAATAGTGATTGTTTTTAAAAGGCAGTATACTCTTACCAG
TGCGAGGTAGCTGGGGCCTGTGATAGTTTTTAGAGATAAGTTCTTCAGGCAACTGTGTATTTTACACTAGTCAAGTAATCCTAGATATCC
GTGGTTTTTCTTAAGAAAGTTGGCTCGTAATATGATTTAATATTCAAAGTAGAGTCATCTACCTATTAGCTTGCTGGCGTGGTCCTAGTT
TATGCCTGTTTCAGCATGATTGTTGAGTACCCTGTTTCATCCTTAGCATTTTCTTGATTTTGTTGTTAAATGATGTATACCCTTATTTCC
ATTGAATCTGTGCTTCCACCCCCCCAACTGAAGTTGTCTTCCCTTTGCTTGGCCACCCTTACAGCCTCTTGGATGGTGTATCCTACAGTG

>21058_21058_2_CYP2E1-GLUL_CYP2E1_chr10_135345788_ENST00000252945_GLUL_chr1_182354691_ENST00000331872_length(amino acids)=388AA_BP=198
MSALGVTVALLVWAAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVKEAL
LDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVI
ADILFRKHFDYNDEKFLRLMYLFNENFHLLSTPWLQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTN
FSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSAN

--------------------------------------------------------------
>21058_21058_3_CYP2E1-GLUL_CYP2E1_chr10_135345788_ENST00000252945_GLUL_chr1_182354691_ENST00000417584_length(transcript)=3900nt_BP=681nt
CTCCCGGGCTGGCAGCAGGGCCCCAGCGGCACCATGTCTGCCCTCGGAGTCACCGTGGCCCTGCTGGTGTGGGCGGCCTTCCTCCTGCTG
GTGTCCATGTGGAGGCAGGTGCACAGCAGCTGGAATCTGCCCCCAGGCCCTTTCCCGCTTCCCATCATCGGGAACCTCTTCCAGTTGGAA
TTGAAGAATATTCCCAAGTCCTTCACCCGGTTGGCCCAGCGCTTCGGGCCGGTGTTCACGCTGTACGTGGGCTCGCAGCGCATGGTGGTG
ATGCACGGCTACAAGGCGGTGAAGGAAGCGCTGCTGGACTACAAGGACGAGTTCTCGGGCAGAGGCGACCTCCCCGCGTTCCATGCGCAC
AGGGACAGGGGAATCATTTTTAATAATGGACCTACCTGGAAGGACATCCGGCGGTTTTCCCTGACCACCCTCCGGAACTATGGGATGGGG
AAACAGGGCAATGAGAGCCGGATCCAGAGGGAGGCCCACTTCCTGCTGGAAGCACTCAGGAAGACCCAAGGCCAGCCTTTCGACCCCACC
TTCCTCATCGGCTGCGCGCCCTGCAACGTCATAGCCGACATCCTCTTCCGCAAGCATTTTGACTACAATGATGAGAAGTTTCTAAGGCTG
ATGTATTTGTTTAATGAGAACTTCCACCTACTCAGCACTCCCTGGCTCCAGTGGGAATTTCAGATTGGACCTTGTGAAGGAATCAGCATG
GGAGATCATCTCTGGGTGGCCCGTTTCATCTTGCATCGTGTGTGTGAAGACTTTGGAGTGATAGCAACCTTTGATCCTAAGCCCATTCCT
GGGAACTGGAATGGTGCAGGCTGCCATACCAACTTCAGCACCAAGGCCATGCGGGAGGAGAATGGTCTGAAGTACATCGAGGAGGCCATT
GAGAAACTAAGCAAGCGGCACCAGTACCACATCCGTGCCTATGATCCCAAGGGAGGCCTGGACAATGCCCGACGTCTAACTGGATTCCAT
GAAACCTCCAACATCAACGACTTTTCTGCTGGTGTAGCCAATCGTAGCGCCAGCATACGCATTCCCCGGACTGTTGGCCAGGAGAAGAAG
GGTTACTTTGAAGATCGTCGCCCCTCTGCCAACTGCGACCCCTTTTCGGTGACAGAAGCCCTCATCCGCACGTGTCTTCTCAATGAAACC
GGCGATGAGCCCTTCCAGTACAAAAATTAAGTGGACTAGACCTCCAGCTGTTGAGCCCCTCCTAGTTCTTCATCCCACTCCAACTCTTCC
CCCTCTCCCAGTTGTCCCGATTGTAACTCAAAGGGTGGAATATCAAGGTCGTTTTTTTCATTCCATGTGCCCAGTTAATCTTGCTTTCTT
TGTTTGGCTGGGATAGAGGGGTCAAGTTATTAATTTCTTCACACCTACCCTCCTTTTTTTCCCTATCACTGAAGCTTTTTAGTGCATTAG
TGGGGAGGAGGGTGGGGAGACATAACCACTGCTTCCATTTAATGGGGTGCACCTGTCCAATAGGCGTAGCTATCCGGACAGAGCACGTTT
GCAGAAGGGGGTCTCTTCTTCCAGGTAGCTGAAAGGGGAAGACCTGACGTACTCTGGTTAGGTTAGGACTTGCCCTCGTGGTGGAAACTT
TTCTTAAAAAGTTATAACCAACTTTTCTATTAAAAGTGGGAATTAGGAGAGAAGGTAGGGGTTGGGAATCAGAGAGAATGGCTTTGGTCT
CTTGCTTGTGGGACTAGCCTGGCTTGGGACTAAATGCCCTGCTCTGAACACGAAGCTTAGTATAAACTGATGGATATCCCTACCTTGAAA
GAAGAAAAGGTTCTTACTGCTTGGTCCTTGATTTATCACACAAAGCAGAATAGTATTTTTATATTTAAATGTAAAGACAAAAAACTATAT
GTATGGTTTTGTGGATTATGTGTGTTTTGCTAAAGGAAAAAACCATCCAGGTCACGGGGCACCAAATTTGAGACAAATAGTCGGATTAGA
AATAAAGCATCTCATTTTGAGTAGAGAGCAAGGGAAGTGGTTCTTAGATGGTGATCTGGGATTAGGCCCTCAAGACCCTTTTGGGTTTCT
GCCCTGCCCACCCTCTGGAGAAGGTGGGCACTGGATTAGTTAACAGACAACACGTTACTAGCAGTCACTTGATCTCCGTGGCTTTGGTTT
AAAAGACACACTTGTCCACATAGGTTTAGAGATAAGAGTTGGCTGGTCAACTTGAGCATGTTACTGACAGAGGGGGTATTGGGGTTATTT
TCTGGTAGGAATAGCATGTCACTAAAGCAGGCCTTTTGATATTAAATTTTTTAAAAAGCAAAATTATAGAAGTTTAGATTTTAATCAAAT
TTGTAGGGTTTCTAGGTAATTTTTACAGAATTGCTTGTTTGCTTCAACTGTCTCCTACCTCTGCTCTTGGAGGAGATGGGGACAGGGCTG
GAGTCAAAACACTTGTAATTTTGTATCTTGATGTCTTTGTTAAGACTGCTGAAGAATTATTTTTTTTCTTTTATAATAAGGAATAAACCC
CACCTTTATTCCTTCATTTCATCTACCATTTTCTGGTTCTTGTGTTGGCTGTGGCAGGCCAGCTGTGGTTTTCTTTTGCCATGACAACTT
CTAATTGCCATGTACAGTATGTTCAAAGTCAAATAACTCCTCATTGTAAACAAACTGTGTAACTGCCCAAAGCAGCACTTATAAATCAGC
CTAACATAAGATCTCTCTGATGTGTTTGTGATTCTTTCAAATCCCTATGTGCCATTATATTTCTTTATTTCCTAAAACAGGCAAAATAAG
CTCAAGTTTATGTACTCTGAGTTTTTAAAACACTGGAGTGATGTTGCTGACCAGCCGTTTCCTGTACCTCTCTAAGTTGGGTATTTGGGA
CTTAAGGGATTAAGTTTTTCACCTAGACTTAGTTACACACAATCTTGGCATTTCCTAGCCTAGAGGTTTGTAGCAGGGTACAAGCCCCAC
TCCTCCCCCTTCCTTTGCTCCCCTGAGTTTGGTTTTGGCTTACCATAACATTGTTTTGACCATTCCTAGCCTAATACAATAGCCTAACAT
AATGTAAGATTAACTGGCTTTACGATTTCTATTCTCTGCTCTCAGTGATAAGAAACAAATATTAGCTACCCTGCTACCCTGGTTGAAGCC
TTCCAAGGCTGGCTATGCCCTAGGCATGGGCTCATCCTTGGGTGTATCTTGCCTTGCAGGAAGACCAGTGGACCGATTGTGATTCTCAAA
AGCTCTGTGTTGTCACCTGTGCCCTTGCCCCTTGCTCTTATCTTGGTCCGTGTATCTGGGAGTTCTTCCACCTTATCTTGGCCAATTCCT
ACCTTCGTTCATTCCTCATGAGGTTGGGTAAAAGCTCCCTCCGGCTCCCATGATGCTGTGCATATACCTAGCAAAAAGCAATTATTGGAC
ACATTGGAGTGCAATATTATTAATAGCATTAATACTACTAATAATGTGGGCAATAGTGATTGTTTTTAAAAGGCAGTATACTCTTACCAG
TGCGAGGTAGCTGGGGCCTGTGATAGTTTTTAGAGATAAGTTCTTCAGGCAACTGTGTATTTTACACTAGTCAAGTAATCCTAGATATCC
GTGGTTTTTCTTAAGAAAGTTGGCTCGTAATATGATTTAATATTCAAAGTAGAGTCATCTACCTATTAGCTTGCTGGCGTGGTCCTAGTT
TATGCCTGTTTCAGCATGATTGTTGAGTACCCTGTTTCATCCTTAGCATTTTCTTGATTTTGTTGTTAAATGATGTATACCCTTATTTCC
ATTGAATCTGTGCTTCCACCCCCCCAACTGAAGTTGTCTTCCCTTTGCTTGGCCACCCTTACAGCCTCTTGGATGGTGTATCCTACAGTG

>21058_21058_3_CYP2E1-GLUL_CYP2E1_chr10_135345788_ENST00000252945_GLUL_chr1_182354691_ENST00000417584_length(amino acids)=388AA_BP=198
MSALGVTVALLVWAAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVKEAL
LDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVI
ADILFRKHFDYNDEKFLRLMYLFNENFHLLSTPWLQWEFQIGPCEGISMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTN
FSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRTVGQEKKGYFEDRRPSAN

--------------------------------------------------------------
>21058_21058_4_CYP2E1-GLUL_CYP2E1_chr10_135345788_ENST00000463117_GLUL_chr1_182354691_ENST00000311223_length(transcript)=4139nt_BP=920nt
ACTTCCGGGTTGTTTGCTCCCGGAGCCATAACCGCAGCTCAGCGTGCGGGCAGAGCCGGCTGACAGGAGACAGGACACAGCACAGAGCCC
CGCGCCCTCTGAGGCGGGAGGCTTCGTTCCTGCACCAGCGTGGCTTGCCCTTTGGACGCGGCGAGTTAACTTGAGAAAGTGGAATCGAAT
TCCGATGTTGAATTTTCCTTCTGGCCCCATTCATGTGGCAGGTGGTGATTCAGGATTGTCTCCCGGGCTGGCAGCAGGGCCCCAGCGGCA
CCATGTCTGCCCTCGGAGTCACCGTGGCCCTGCTGGTGTGGGCGGCCTTCCTCCTGCTGGTGTCCATGTGGAGGCAGGTGCACAGCAGCT
GGAATCTGCCCCCAGGCCCTTTCCCGCTTCCCATCATCGGGAACCTCTTCCAGTTGGAATTGAAGAATATTCCCAAGTCCTTCACCCGGT
TGGCCCAGCGCTTCGGGCCGGTGTTCACGCTGTACGTGGGCTCGCAGCGCATGGTGGTGATGCACGGCTACAAGGCGGTGAAGGAAGCGC
TGCTGGACTACAAGGACGAGTTCTCGGGCAGAGGCGACCTCCCCGCGTTCCATGCGCACAGGGACAGGGGAATCATTTTTAATAATGGAC
CTACCTGGAAGGACATCCGGCGGTTTTCCCTGACCACCCTCCGGAACTATGGGATGGGGAAACAGGGCAATGAGAGCCGGATCCAGAGGG
AGGCCCACTTCCTGCTGGAAGCACTCAGGAAGACCCAAGGCCAGCCTTTCGACCCCACCTTCCTCATCGGCTGCGCGCCCTGCAACGTCA
TAGCCGACATCCTCTTCCGCAAGCATTTTGACTACAATGATGAGAAGTTTCTAAGGCTGATGTATTTGTTTAATGAGAACTTCCACCTAC
TCAGCACTCCCTGGCTCCAGTGGGAATTTCAGATTGGACCTTGTGAAGGAATCAGCATGGGAGATCATCTCTGGGTGGCCCGTTTCATCT
TGCATCGTGTGTGTGAAGACTTTGGAGTGATAGCAACCTTTGATCCTAAGCCCATTCCTGGGAACTGGAATGGTGCAGGCTGCCATACCA
ACTTCAGCACCAAGGCCATGCGGGAGGAGAATGGTCTGAAGTACATCGAGGAGGCCATTGAGAAACTAAGCAAGCGGCACCAGTACCACA
TCCGTGCCTATGATCCCAAGGGAGGCCTGGACAATGCCCGACGTCTAACTGGATTCCATGAAACCTCCAACATCAACGACTTTTCTGCTG
GTGTAGCCAATCGTAGCGCCAGCATACGCATTCCCCGGACTGTTGGCCAGGAGAAGAAGGGTTACTTTGAAGATCGTCGCCCCTCTGCCA
ACTGCGACCCCTTTTCGGTGACAGAAGCCCTCATCCGCACGTGTCTTCTCAATGAAACCGGCGATGAGCCCTTCCAGTACAAAAATTAAG
TGGACTAGACCTCCAGCTGTTGAGCCCCTCCTAGTTCTTCATCCCACTCCAACTCTTCCCCCTCTCCCAGTTGTCCCGATTGTAACTCAA
AGGGTGGAATATCAAGGTCGTTTTTTTCATTCCATGTGCCCAGTTAATCTTGCTTTCTTTGTTTGGCTGGGATAGAGGGGTCAAGTTATT
AATTTCTTCACACCTACCCTCCTTTTTTTCCCTATCACTGAAGCTTTTTAGTGCATTAGTGGGGAGGAGGGTGGGGAGACATAACCACTG
CTTCCATTTAATGGGGTGCACCTGTCCAATAGGCGTAGCTATCCGGACAGAGCACGTTTGCAGAAGGGGGTCTCTTCTTCCAGGTAGCTG
AAAGGGGAAGACCTGACGTACTCTGGTTAGGTTAGGACTTGCCCTCGTGGTGGAAACTTTTCTTAAAAAGTTATAACCAACTTTTCTATT
AAAAGTGGGAATTAGGAGAGAAGGTAGGGGTTGGGAATCAGAGAGAATGGCTTTGGTCTCTTGCTTGTGGGACTAGCCTGGCTTGGGACT
AAATGCCCTGCTCTGAACACGAAGCTTAGTATAAACTGATGGATATCCCTACCTTGAAAGAAGAAAAGGTTCTTACTGCTTGGTCCTTGA
TTTATCACACAAAGCAGAATAGTATTTTTATATTTAAATGTAAAGACAAAAAACTATATGTATGGTTTTGTGGATTATGTGTGTTTTGCT
AAAGGAAAAAACCATCCAGGTCACGGGGCACCAAATTTGAGACAAATAGTCGGATTAGAAATAAAGCATCTCATTTTGAGTAGAGAGCAA
GGGAAGTGGTTCTTAGATGGTGATCTGGGATTAGGCCCTCAAGACCCTTTTGGGTTTCTGCCCTGCCCACCCTCTGGAGAAGGTGGGCAC
TGGATTAGTTAACAGACAACACGTTACTAGCAGTCACTTGATCTCCGTGGCTTTGGTTTAAAAGACACACTTGTCCACATAGGTTTAGAG
ATAAGAGTTGGCTGGTCAACTTGAGCATGTTACTGACAGAGGGGGTATTGGGGTTATTTTCTGGTAGGAATAGCATGTCACTAAAGCAGG
CCTTTTGATATTAAATTTTTTAAAAAGCAAAATTATAGAAGTTTAGATTTTAATCAAATTTGTAGGGTTTCTAGGTAATTTTTACAGAAT
TGCTTGTTTGCTTCAACTGTCTCCTACCTCTGCTCTTGGAGGAGATGGGGACAGGGCTGGAGTCAAAACACTTGTAATTTTGTATCTTGA
TGTCTTTGTTAAGACTGCTGAAGAATTATTTTTTTTCTTTTATAATAAGGAATAAACCCCACCTTTATTCCTTCATTTCATCTACCATTT
TCTGGTTCTTGTGTTGGCTGTGGCAGGCCAGCTGTGGTTTTCTTTTGCCATGACAACTTCTAATTGCCATGTACAGTATGTTCAAAGTCA
AATAACTCCTCATTGTAAACAAACTGTGTAACTGCCCAAAGCAGCACTTATAAATCAGCCTAACATAAGATCTCTCTGATGTGTTTGTGA
TTCTTTCAAATCCCTATGTGCCATTATATTTCTTTATTTCCTAAAACAGGCAAAATAAGCTCAAGTTTATGTACTCTGAGTTTTTAAAAC
ACTGGAGTGATGTTGCTGACCAGCCGTTTCCTGTACCTCTCTAAGTTGGGTATTTGGGACTTAAGGGATTAAGTTTTTCACCTAGACTTA
GTTACACACAATCTTGGCATTTCCTAGCCTAGAGGTTTGTAGCAGGGTACAAGCCCCACTCCTCCCCCTTCCTTTGCTCCCCTGAGTTTG
GTTTTGGCTTACCATAACATTGTTTTGACCATTCCTAGCCTAATACAATAGCCTAACATAATGTAAGATTAACTGGCTTTACGATTTCTA
TTCTCTGCTCTCAGTGATAAGAAACAAATATTAGCTACCCTGCTACCCTGGTTGAAGCCTTCCAAGGCTGGCTATGCCCTAGGCATGGGC
TCATCCTTGGGTGTATCTTGCCTTGCAGGAAGACCAGTGGACCGATTGTGATTCTCAAAAGCTCTGTGTTGTCACCTGTGCCCTTGCCCC
TTGCTCTTATCTTGGTCCGTGTATCTGGGAGTTCTTCCACCTTATCTTGGCCAATTCCTACCTTCGTTCATTCCTCATGAGGTTGGGTAA
AAGCTCCCTCCGGCTCCCATGATGCTGTGCATATACCTAGCAAAAAGCAATTATTGGACACATTGGAGTGCAATATTATTAATAGCATTA
ATACTACTAATAATGTGGGCAATAGTGATTGTTTTTAAAAGGCAGTATACTCTTACCAGTGCGAGGTAGCTGGGGCCTGTGATAGTTTTT
AGAGATAAGTTCTTCAGGCAACTGTGTATTTTACACTAGTCAAGTAATCCTAGATATCCGTGGTTTTTCTTAAGAAAGTTGGCTCGTAAT
ATGATTTAATATTCAAAGTAGAGTCATCTACCTATTAGCTTGCTGGCGTGGTCCTAGTTTATGCCTGTTTCAGCATGATTGTTGAGTACC
CTGTTTCATCCTTAGCATTTTCTTGATTTTGTTGTTAAATGATGTATACCCTTATTTCCATTGAATCTGTGCTTCCACCCCCCCAACTGA

>21058_21058_4_CYP2E1-GLUL_CYP2E1_chr10_135345788_ENST00000463117_GLUL_chr1_182354691_ENST00000311223_length(amino acids)=412AA_BP=222
MAPFMWQVVIQDCLPGWQQGPSGTMSALGVTVALLVWAAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGP
VFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLE
ALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNENFHLLSTPWLQWEFQIGPCEGISMGDHLWVARFILHRVCED
FGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSA

--------------------------------------------------------------
>21058_21058_5_CYP2E1-GLUL_CYP2E1_chr10_135345788_ENST00000463117_GLUL_chr1_182354691_ENST00000331872_length(transcript)=4140nt_BP=920nt
ACTTCCGGGTTGTTTGCTCCCGGAGCCATAACCGCAGCTCAGCGTGCGGGCAGAGCCGGCTGACAGGAGACAGGACACAGCACAGAGCCC
CGCGCCCTCTGAGGCGGGAGGCTTCGTTCCTGCACCAGCGTGGCTTGCCCTTTGGACGCGGCGAGTTAACTTGAGAAAGTGGAATCGAAT
TCCGATGTTGAATTTTCCTTCTGGCCCCATTCATGTGGCAGGTGGTGATTCAGGATTGTCTCCCGGGCTGGCAGCAGGGCCCCAGCGGCA
CCATGTCTGCCCTCGGAGTCACCGTGGCCCTGCTGGTGTGGGCGGCCTTCCTCCTGCTGGTGTCCATGTGGAGGCAGGTGCACAGCAGCT
GGAATCTGCCCCCAGGCCCTTTCCCGCTTCCCATCATCGGGAACCTCTTCCAGTTGGAATTGAAGAATATTCCCAAGTCCTTCACCCGGT
TGGCCCAGCGCTTCGGGCCGGTGTTCACGCTGTACGTGGGCTCGCAGCGCATGGTGGTGATGCACGGCTACAAGGCGGTGAAGGAAGCGC
TGCTGGACTACAAGGACGAGTTCTCGGGCAGAGGCGACCTCCCCGCGTTCCATGCGCACAGGGACAGGGGAATCATTTTTAATAATGGAC
CTACCTGGAAGGACATCCGGCGGTTTTCCCTGACCACCCTCCGGAACTATGGGATGGGGAAACAGGGCAATGAGAGCCGGATCCAGAGGG
AGGCCCACTTCCTGCTGGAAGCACTCAGGAAGACCCAAGGCCAGCCTTTCGACCCCACCTTCCTCATCGGCTGCGCGCCCTGCAACGTCA
TAGCCGACATCCTCTTCCGCAAGCATTTTGACTACAATGATGAGAAGTTTCTAAGGCTGATGTATTTGTTTAATGAGAACTTCCACCTAC
TCAGCACTCCCTGGCTCCAGTGGGAATTTCAGATTGGACCTTGTGAAGGAATCAGCATGGGAGATCATCTCTGGGTGGCCCGTTTCATCT
TGCATCGTGTGTGTGAAGACTTTGGAGTGATAGCAACCTTTGATCCTAAGCCCATTCCTGGGAACTGGAATGGTGCAGGCTGCCATACCA
ACTTCAGCACCAAGGCCATGCGGGAGGAGAATGGTCTGAAGTACATCGAGGAGGCCATTGAGAAACTAAGCAAGCGGCACCAGTACCACA
TCCGTGCCTATGATCCCAAGGGAGGCCTGGACAATGCCCGACGTCTAACTGGATTCCATGAAACCTCCAACATCAACGACTTTTCTGCTG
GTGTAGCCAATCGTAGCGCCAGCATACGCATTCCCCGGACTGTTGGCCAGGAGAAGAAGGGTTACTTTGAAGATCGTCGCCCCTCTGCCA
ACTGCGACCCCTTTTCGGTGACAGAAGCCCTCATCCGCACGTGTCTTCTCAATGAAACCGGCGATGAGCCCTTCCAGTACAAAAATTAAG
TGGACTAGACCTCCAGCTGTTGAGCCCCTCCTAGTTCTTCATCCCACTCCAACTCTTCCCCCTCTCCCAGTTGTCCCGATTGTAACTCAA
AGGGTGGAATATCAAGGTCGTTTTTTTCATTCCATGTGCCCAGTTAATCTTGCTTTCTTTGTTTGGCTGGGATAGAGGGGTCAAGTTATT
AATTTCTTCACACCTACCCTCCTTTTTTTCCCTATCACTGAAGCTTTTTAGTGCATTAGTGGGGAGGAGGGTGGGGAGACATAACCACTG
CTTCCATTTAATGGGGTGCACCTGTCCAATAGGCGTAGCTATCCGGACAGAGCACGTTTGCAGAAGGGGGTCTCTTCTTCCAGGTAGCTG
AAAGGGGAAGACCTGACGTACTCTGGTTAGGTTAGGACTTGCCCTCGTGGTGGAAACTTTTCTTAAAAAGTTATAACCAACTTTTCTATT
AAAAGTGGGAATTAGGAGAGAAGGTAGGGGTTGGGAATCAGAGAGAATGGCTTTGGTCTCTTGCTTGTGGGACTAGCCTGGCTTGGGACT
AAATGCCCTGCTCTGAACACGAAGCTTAGTATAAACTGATGGATATCCCTACCTTGAAAGAAGAAAAGGTTCTTACTGCTTGGTCCTTGA
TTTATCACACAAAGCAGAATAGTATTTTTATATTTAAATGTAAAGACAAAAAACTATATGTATGGTTTTGTGGATTATGTGTGTTTTGCT
AAAGGAAAAAACCATCCAGGTCACGGGGCACCAAATTTGAGACAAATAGTCGGATTAGAAATAAAGCATCTCATTTTGAGTAGAGAGCAA
GGGAAGTGGTTCTTAGATGGTGATCTGGGATTAGGCCCTCAAGACCCTTTTGGGTTTCTGCCCTGCCCACCCTCTGGAGAAGGTGGGCAC
TGGATTAGTTAACAGACAACACGTTACTAGCAGTCACTTGATCTCCGTGGCTTTGGTTTAAAAGACACACTTGTCCACATAGGTTTAGAG
ATAAGAGTTGGCTGGTCAACTTGAGCATGTTACTGACAGAGGGGGTATTGGGGTTATTTTCTGGTAGGAATAGCATGTCACTAAAGCAGG
CCTTTTGATATTAAATTTTTTAAAAAGCAAAATTATAGAAGTTTAGATTTTAATCAAATTTGTAGGGTTTCTAGGTAATTTTTACAGAAT
TGCTTGTTTGCTTCAACTGTCTCCTACCTCTGCTCTTGGAGGAGATGGGGACAGGGCTGGAGTCAAAACACTTGTAATTTTGTATCTTGA
TGTCTTTGTTAAGACTGCTGAAGAATTATTTTTTTTCTTTTATAATAAGGAATAAACCCCACCTTTATTCCTTCATTTCATCTACCATTT
TCTGGTTCTTGTGTTGGCTGTGGCAGGCCAGCTGTGGTTTTCTTTTGCCATGACAACTTCTAATTGCCATGTACAGTATGTTCAAAGTCA
AATAACTCCTCATTGTAAACAAACTGTGTAACTGCCCAAAGCAGCACTTATAAATCAGCCTAACATAAGATCTCTCTGATGTGTTTGTGA
TTCTTTCAAATCCCTATGTGCCATTATATTTCTTTATTTCCTAAAACAGGCAAAATAAGCTCAAGTTTATGTACTCTGAGTTTTTAAAAC
ACTGGAGTGATGTTGCTGACCAGCCGTTTCCTGTACCTCTCTAAGTTGGGTATTTGGGACTTAAGGGATTAAGTTTTTCACCTAGACTTA
GTTACACACAATCTTGGCATTTCCTAGCCTAGAGGTTTGTAGCAGGGTACAAGCCCCACTCCTCCCCCTTCCTTTGCTCCCCTGAGTTTG
GTTTTGGCTTACCATAACATTGTTTTGACCATTCCTAGCCTAATACAATAGCCTAACATAATGTAAGATTAACTGGCTTTACGATTTCTA
TTCTCTGCTCTCAGTGATAAGAAACAAATATTAGCTACCCTGCTACCCTGGTTGAAGCCTTCCAAGGCTGGCTATGCCCTAGGCATGGGC
TCATCCTTGGGTGTATCTTGCCTTGCAGGAAGACCAGTGGACCGATTGTGATTCTCAAAAGCTCTGTGTTGTCACCTGTGCCCTTGCCCC
TTGCTCTTATCTTGGTCCGTGTATCTGGGAGTTCTTCCACCTTATCTTGGCCAATTCCTACCTTCGTTCATTCCTCATGAGGTTGGGTAA
AAGCTCCCTCCGGCTCCCATGATGCTGTGCATATACCTAGCAAAAAGCAATTATTGGACACATTGGAGTGCAATATTATTAATAGCATTA
ATACTACTAATAATGTGGGCAATAGTGATTGTTTTTAAAAGGCAGTATACTCTTACCAGTGCGAGGTAGCTGGGGCCTGTGATAGTTTTT
AGAGATAAGTTCTTCAGGCAACTGTGTATTTTACACTAGTCAAGTAATCCTAGATATCCGTGGTTTTTCTTAAGAAAGTTGGCTCGTAAT
ATGATTTAATATTCAAAGTAGAGTCATCTACCTATTAGCTTGCTGGCGTGGTCCTAGTTTATGCCTGTTTCAGCATGATTGTTGAGTACC
CTGTTTCATCCTTAGCATTTTCTTGATTTTGTTGTTAAATGATGTATACCCTTATTTCCATTGAATCTGTGCTTCCACCCCCCCAACTGA
AGTTGTCTTCCCTTTGCTTGGCCACCCTTACAGCCTCTTGGATGGTGTATCCTACAGTGTAAGCACTAAACTGAAGAGGCAGTGACCTGA

>21058_21058_5_CYP2E1-GLUL_CYP2E1_chr10_135345788_ENST00000463117_GLUL_chr1_182354691_ENST00000331872_length(amino acids)=412AA_BP=222
MAPFMWQVVIQDCLPGWQQGPSGTMSALGVTVALLVWAAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGP
VFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLE
ALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNENFHLLSTPWLQWEFQIGPCEGISMGDHLWVARFILHRVCED
FGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSA

--------------------------------------------------------------
>21058_21058_6_CYP2E1-GLUL_CYP2E1_chr10_135345788_ENST00000463117_GLUL_chr1_182354691_ENST00000417584_length(transcript)=4139nt_BP=920nt
ACTTCCGGGTTGTTTGCTCCCGGAGCCATAACCGCAGCTCAGCGTGCGGGCAGAGCCGGCTGACAGGAGACAGGACACAGCACAGAGCCC
CGCGCCCTCTGAGGCGGGAGGCTTCGTTCCTGCACCAGCGTGGCTTGCCCTTTGGACGCGGCGAGTTAACTTGAGAAAGTGGAATCGAAT
TCCGATGTTGAATTTTCCTTCTGGCCCCATTCATGTGGCAGGTGGTGATTCAGGATTGTCTCCCGGGCTGGCAGCAGGGCCCCAGCGGCA
CCATGTCTGCCCTCGGAGTCACCGTGGCCCTGCTGGTGTGGGCGGCCTTCCTCCTGCTGGTGTCCATGTGGAGGCAGGTGCACAGCAGCT
GGAATCTGCCCCCAGGCCCTTTCCCGCTTCCCATCATCGGGAACCTCTTCCAGTTGGAATTGAAGAATATTCCCAAGTCCTTCACCCGGT
TGGCCCAGCGCTTCGGGCCGGTGTTCACGCTGTACGTGGGCTCGCAGCGCATGGTGGTGATGCACGGCTACAAGGCGGTGAAGGAAGCGC
TGCTGGACTACAAGGACGAGTTCTCGGGCAGAGGCGACCTCCCCGCGTTCCATGCGCACAGGGACAGGGGAATCATTTTTAATAATGGAC
CTACCTGGAAGGACATCCGGCGGTTTTCCCTGACCACCCTCCGGAACTATGGGATGGGGAAACAGGGCAATGAGAGCCGGATCCAGAGGG
AGGCCCACTTCCTGCTGGAAGCACTCAGGAAGACCCAAGGCCAGCCTTTCGACCCCACCTTCCTCATCGGCTGCGCGCCCTGCAACGTCA
TAGCCGACATCCTCTTCCGCAAGCATTTTGACTACAATGATGAGAAGTTTCTAAGGCTGATGTATTTGTTTAATGAGAACTTCCACCTAC
TCAGCACTCCCTGGCTCCAGTGGGAATTTCAGATTGGACCTTGTGAAGGAATCAGCATGGGAGATCATCTCTGGGTGGCCCGTTTCATCT
TGCATCGTGTGTGTGAAGACTTTGGAGTGATAGCAACCTTTGATCCTAAGCCCATTCCTGGGAACTGGAATGGTGCAGGCTGCCATACCA
ACTTCAGCACCAAGGCCATGCGGGAGGAGAATGGTCTGAAGTACATCGAGGAGGCCATTGAGAAACTAAGCAAGCGGCACCAGTACCACA
TCCGTGCCTATGATCCCAAGGGAGGCCTGGACAATGCCCGACGTCTAACTGGATTCCATGAAACCTCCAACATCAACGACTTTTCTGCTG
GTGTAGCCAATCGTAGCGCCAGCATACGCATTCCCCGGACTGTTGGCCAGGAGAAGAAGGGTTACTTTGAAGATCGTCGCCCCTCTGCCA
ACTGCGACCCCTTTTCGGTGACAGAAGCCCTCATCCGCACGTGTCTTCTCAATGAAACCGGCGATGAGCCCTTCCAGTACAAAAATTAAG
TGGACTAGACCTCCAGCTGTTGAGCCCCTCCTAGTTCTTCATCCCACTCCAACTCTTCCCCCTCTCCCAGTTGTCCCGATTGTAACTCAA
AGGGTGGAATATCAAGGTCGTTTTTTTCATTCCATGTGCCCAGTTAATCTTGCTTTCTTTGTTTGGCTGGGATAGAGGGGTCAAGTTATT
AATTTCTTCACACCTACCCTCCTTTTTTTCCCTATCACTGAAGCTTTTTAGTGCATTAGTGGGGAGGAGGGTGGGGAGACATAACCACTG
CTTCCATTTAATGGGGTGCACCTGTCCAATAGGCGTAGCTATCCGGACAGAGCACGTTTGCAGAAGGGGGTCTCTTCTTCCAGGTAGCTG
AAAGGGGAAGACCTGACGTACTCTGGTTAGGTTAGGACTTGCCCTCGTGGTGGAAACTTTTCTTAAAAAGTTATAACCAACTTTTCTATT
AAAAGTGGGAATTAGGAGAGAAGGTAGGGGTTGGGAATCAGAGAGAATGGCTTTGGTCTCTTGCTTGTGGGACTAGCCTGGCTTGGGACT
AAATGCCCTGCTCTGAACACGAAGCTTAGTATAAACTGATGGATATCCCTACCTTGAAAGAAGAAAAGGTTCTTACTGCTTGGTCCTTGA
TTTATCACACAAAGCAGAATAGTATTTTTATATTTAAATGTAAAGACAAAAAACTATATGTATGGTTTTGTGGATTATGTGTGTTTTGCT
AAAGGAAAAAACCATCCAGGTCACGGGGCACCAAATTTGAGACAAATAGTCGGATTAGAAATAAAGCATCTCATTTTGAGTAGAGAGCAA
GGGAAGTGGTTCTTAGATGGTGATCTGGGATTAGGCCCTCAAGACCCTTTTGGGTTTCTGCCCTGCCCACCCTCTGGAGAAGGTGGGCAC
TGGATTAGTTAACAGACAACACGTTACTAGCAGTCACTTGATCTCCGTGGCTTTGGTTTAAAAGACACACTTGTCCACATAGGTTTAGAG
ATAAGAGTTGGCTGGTCAACTTGAGCATGTTACTGACAGAGGGGGTATTGGGGTTATTTTCTGGTAGGAATAGCATGTCACTAAAGCAGG
CCTTTTGATATTAAATTTTTTAAAAAGCAAAATTATAGAAGTTTAGATTTTAATCAAATTTGTAGGGTTTCTAGGTAATTTTTACAGAAT
TGCTTGTTTGCTTCAACTGTCTCCTACCTCTGCTCTTGGAGGAGATGGGGACAGGGCTGGAGTCAAAACACTTGTAATTTTGTATCTTGA
TGTCTTTGTTAAGACTGCTGAAGAATTATTTTTTTTCTTTTATAATAAGGAATAAACCCCACCTTTATTCCTTCATTTCATCTACCATTT
TCTGGTTCTTGTGTTGGCTGTGGCAGGCCAGCTGTGGTTTTCTTTTGCCATGACAACTTCTAATTGCCATGTACAGTATGTTCAAAGTCA
AATAACTCCTCATTGTAAACAAACTGTGTAACTGCCCAAAGCAGCACTTATAAATCAGCCTAACATAAGATCTCTCTGATGTGTTTGTGA
TTCTTTCAAATCCCTATGTGCCATTATATTTCTTTATTTCCTAAAACAGGCAAAATAAGCTCAAGTTTATGTACTCTGAGTTTTTAAAAC
ACTGGAGTGATGTTGCTGACCAGCCGTTTCCTGTACCTCTCTAAGTTGGGTATTTGGGACTTAAGGGATTAAGTTTTTCACCTAGACTTA
GTTACACACAATCTTGGCATTTCCTAGCCTAGAGGTTTGTAGCAGGGTACAAGCCCCACTCCTCCCCCTTCCTTTGCTCCCCTGAGTTTG
GTTTTGGCTTACCATAACATTGTTTTGACCATTCCTAGCCTAATACAATAGCCTAACATAATGTAAGATTAACTGGCTTTACGATTTCTA
TTCTCTGCTCTCAGTGATAAGAAACAAATATTAGCTACCCTGCTACCCTGGTTGAAGCCTTCCAAGGCTGGCTATGCCCTAGGCATGGGC
TCATCCTTGGGTGTATCTTGCCTTGCAGGAAGACCAGTGGACCGATTGTGATTCTCAAAAGCTCTGTGTTGTCACCTGTGCCCTTGCCCC
TTGCTCTTATCTTGGTCCGTGTATCTGGGAGTTCTTCCACCTTATCTTGGCCAATTCCTACCTTCGTTCATTCCTCATGAGGTTGGGTAA
AAGCTCCCTCCGGCTCCCATGATGCTGTGCATATACCTAGCAAAAAGCAATTATTGGACACATTGGAGTGCAATATTATTAATAGCATTA
ATACTACTAATAATGTGGGCAATAGTGATTGTTTTTAAAAGGCAGTATACTCTTACCAGTGCGAGGTAGCTGGGGCCTGTGATAGTTTTT
AGAGATAAGTTCTTCAGGCAACTGTGTATTTTACACTAGTCAAGTAATCCTAGATATCCGTGGTTTTTCTTAAGAAAGTTGGCTCGTAAT
ATGATTTAATATTCAAAGTAGAGTCATCTACCTATTAGCTTGCTGGCGTGGTCCTAGTTTATGCCTGTTTCAGCATGATTGTTGAGTACC
CTGTTTCATCCTTAGCATTTTCTTGATTTTGTTGTTAAATGATGTATACCCTTATTTCCATTGAATCTGTGCTTCCACCCCCCCAACTGA

>21058_21058_6_CYP2E1-GLUL_CYP2E1_chr10_135345788_ENST00000463117_GLUL_chr1_182354691_ENST00000417584_length(amino acids)=412AA_BP=222
MAPFMWQVVIQDCLPGWQQGPSGTMSALGVTVALLVWAAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGP
VFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLE
ALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNENFHLLSTPWLQWEFQIGPCEGISMGDHLWVARFILHRVCED
FGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLKYIEEAIEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSA

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Fusion Gene PPI Analysis for CYP2E1-GLUL


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for CYP2E1-GLUL


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for CYP2E1-GLUL


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource