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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:CYSTM1-MPP7 (FusionGDB2 ID:21130) |
Fusion Gene Summary for CYSTM1-MPP7 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: CYSTM1-MPP7 | Fusion gene ID: 21130 | Hgene | Tgene | Gene symbol | CYSTM1 | MPP7 | Gene ID | 84418 | 143098 |
| Gene name | cysteine rich transmembrane module containing 1 | membrane palmitoylated protein 7 | |
| Synonyms | C5orf32|ORF1-FL49 | - | |
| Cytomap | 5q31.3 | 10p12.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | cysteine-rich and transmembrane domain-containing protein 1UPF0467 protein C5orf32putative nuclear protein ORF1-FL49 | MAGUK p55 subfamily member 7membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | Q9H1C7 | Q5T2T1 | |
| Ensembl transtripts involved in fusion gene | ENST00000261811, ENST00000509789, | ENST00000481244, ENST00000337532, ENST00000375719, ENST00000375732, ENST00000445954, ENST00000540098, | |
| Fusion gene scores | * DoF score | 8 X 3 X 6=144 | 3 X 3 X 2=18 |
| # samples | 8 | 3 | |
| ** MAII score | log2(8/144*10)=-0.84799690655495 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: CYSTM1 [Title/Abstract] AND MPP7 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | CYSTM1(139574237)-MPP7(28378770), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | MPP7 | GO:0031334 | positive regulation of protein complex assembly | 17237226 |
| Tgene | MPP7 | GO:0070830 | bicellular tight junction assembly | 17332497 |
| Fusion gene breakpoints across CYSTM1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across MPP7 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | STAD | TCGA-FP-8209 | CYSTM1 | chr5 | 139574237 | + | MPP7 | chr10 | 28378770 | - |
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Fusion Gene ORF analysis for CYSTM1-MPP7 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000261811 | ENST00000481244 | CYSTM1 | chr5 | 139574237 | + | MPP7 | chr10 | 28378770 | - |
| In-frame | ENST00000261811 | ENST00000337532 | CYSTM1 | chr5 | 139574237 | + | MPP7 | chr10 | 28378770 | - |
| In-frame | ENST00000261811 | ENST00000375719 | CYSTM1 | chr5 | 139574237 | + | MPP7 | chr10 | 28378770 | - |
| In-frame | ENST00000261811 | ENST00000375732 | CYSTM1 | chr5 | 139574237 | + | MPP7 | chr10 | 28378770 | - |
| In-frame | ENST00000261811 | ENST00000445954 | CYSTM1 | chr5 | 139574237 | + | MPP7 | chr10 | 28378770 | - |
| In-frame | ENST00000261811 | ENST00000540098 | CYSTM1 | chr5 | 139574237 | + | MPP7 | chr10 | 28378770 | - |
| intron-3CDS | ENST00000509789 | ENST00000337532 | CYSTM1 | chr5 | 139574237 | + | MPP7 | chr10 | 28378770 | - |
| intron-3CDS | ENST00000509789 | ENST00000375719 | CYSTM1 | chr5 | 139574237 | + | MPP7 | chr10 | 28378770 | - |
| intron-3CDS | ENST00000509789 | ENST00000375732 | CYSTM1 | chr5 | 139574237 | + | MPP7 | chr10 | 28378770 | - |
| intron-3CDS | ENST00000509789 | ENST00000445954 | CYSTM1 | chr5 | 139574237 | + | MPP7 | chr10 | 28378770 | - |
| intron-3CDS | ENST00000509789 | ENST00000540098 | CYSTM1 | chr5 | 139574237 | + | MPP7 | chr10 | 28378770 | - |
| intron-intron | ENST00000509789 | ENST00000481244 | CYSTM1 | chr5 | 139574237 | + | MPP7 | chr10 | 28378770 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000261811 | CYSTM1 | chr5 | 139574237 | + | ENST00000337532 | MPP7 | chr10 | 28378770 | - | 4702 | 851 | 553 | 1629 | 358 |
| ENST00000261811 | CYSTM1 | chr5 | 139574237 | + | ENST00000375732 | MPP7 | chr10 | 28378770 | - | 4702 | 851 | 553 | 1629 | 358 |
| ENST00000261811 | CYSTM1 | chr5 | 139574237 | + | ENST00000540098 | MPP7 | chr10 | 28378770 | - | 4526 | 851 | 553 | 1629 | 358 |
| ENST00000261811 | CYSTM1 | chr5 | 139574237 | + | ENST00000375719 | MPP7 | chr10 | 28378770 | - | 1634 | 851 | 553 | 1629 | 358 |
| ENST00000261811 | CYSTM1 | chr5 | 139574237 | + | ENST00000445954 | MPP7 | chr10 | 28378770 | - | 1537 | 851 | 553 | 1398 | 281 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000261811 | ENST00000337532 | CYSTM1 | chr5 | 139574237 | + | MPP7 | chr10 | 28378770 | - | 0.000169522 | 0.9998305 |
| ENST00000261811 | ENST00000375732 | CYSTM1 | chr5 | 139574237 | + | MPP7 | chr10 | 28378770 | - | 0.000169522 | 0.9998305 |
| ENST00000261811 | ENST00000540098 | CYSTM1 | chr5 | 139574237 | + | MPP7 | chr10 | 28378770 | - | 0.000222753 | 0.99977726 |
| ENST00000261811 | ENST00000375719 | CYSTM1 | chr5 | 139574237 | + | MPP7 | chr10 | 28378770 | - | 0.001934031 | 0.998066 |
| ENST00000261811 | ENST00000445954 | CYSTM1 | chr5 | 139574237 | + | MPP7 | chr10 | 28378770 | - | 0.003950798 | 0.9960492 |
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Fusion Genomic Features for CYSTM1-MPP7 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for CYSTM1-MPP7 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:139574237/chr10:28378770) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| CYSTM1 | MPP7 |
| FUNCTION: Acts as an important adapter that promotes epithelial cell polarity and tight junction formation via its interaction with DLG1. Involved in the assembly of protein complexes at sites of cell-cell contact. {ECO:0000269|PubMed:17332497}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CYSTM1 | chr5:139574237 | chr10:28378770 | ENST00000261811 | + | 2 | 3 | 6_59 | 62 | 98.0 | Compositional bias | Note=Pro-rich |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000337532 | 11 | 18 | 368_560 | 317 | 577.0 | Domain | Guanylate kinase-like | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000375719 | 12 | 19 | 368_560 | 317 | 577.0 | Domain | Guanylate kinase-like | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000375732 | 10 | 17 | 368_560 | 317 | 577.0 | Domain | Guanylate kinase-like | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000540098 | 9 | 16 | 368_560 | 317 | 577.0 | Domain | Guanylate kinase-like |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | CYSTM1 | chr5:139574237 | chr10:28378770 | ENST00000261811 | + | 2 | 3 | 88_91 | 62 | 98.0 | Compositional bias | Note=Poly-Cys |
| Hgene | CYSTM1 | chr5:139574237 | chr10:28378770 | ENST00000261811 | + | 2 | 3 | 74_91 | 62 | 98.0 | Transmembrane | Helical |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000337532 | 11 | 18 | 10_65 | 317 | 577.0 | Domain | L27 1 | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000337532 | 11 | 18 | 139_220 | 317 | 577.0 | Domain | PDZ | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000337532 | 11 | 18 | 228_298 | 317 | 577.0 | Domain | SH3 | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000337532 | 11 | 18 | 67_122 | 317 | 577.0 | Domain | L27 2 | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000375719 | 12 | 19 | 10_65 | 317 | 577.0 | Domain | L27 1 | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000375719 | 12 | 19 | 139_220 | 317 | 577.0 | Domain | PDZ | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000375719 | 12 | 19 | 228_298 | 317 | 577.0 | Domain | SH3 | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000375719 | 12 | 19 | 67_122 | 317 | 577.0 | Domain | L27 2 | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000375732 | 10 | 17 | 10_65 | 317 | 577.0 | Domain | L27 1 | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000375732 | 10 | 17 | 139_220 | 317 | 577.0 | Domain | PDZ | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000375732 | 10 | 17 | 228_298 | 317 | 577.0 | Domain | SH3 | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000375732 | 10 | 17 | 67_122 | 317 | 577.0 | Domain | L27 2 | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000540098 | 9 | 16 | 10_65 | 317 | 577.0 | Domain | L27 1 | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000540098 | 9 | 16 | 139_220 | 317 | 577.0 | Domain | PDZ | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000540098 | 9 | 16 | 228_298 | 317 | 577.0 | Domain | SH3 | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000540098 | 9 | 16 | 67_122 | 317 | 577.0 | Domain | L27 2 | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000337532 | 11 | 18 | 289_383 | 317 | 577.0 | Region | Phospho-regulated basic and hydrophobic (PRBH) motif | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000375719 | 12 | 19 | 289_383 | 317 | 577.0 | Region | Phospho-regulated basic and hydrophobic (PRBH) motif | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000375732 | 10 | 17 | 289_383 | 317 | 577.0 | Region | Phospho-regulated basic and hydrophobic (PRBH) motif | |
| Tgene | MPP7 | chr5:139574237 | chr10:28378770 | ENST00000540098 | 9 | 16 | 289_383 | 317 | 577.0 | Region | Phospho-regulated basic and hydrophobic (PRBH) motif |
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Fusion Gene Sequence for CYSTM1-MPP7 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >21130_21130_1_CYSTM1-MPP7_CYSTM1_chr5_139574237_ENST00000261811_MPP7_chr10_28378770_ENST00000337532_length(transcript)=4702nt_BP=851nt TACTGGCGGGACTACTTGTTGCAAGGTTTATGGGGAAAAGTAGCCAGAGAGCAATCCAGTTATCAGCCTCAGCCCCATTCCGCTCAGGTA CAGCTCGGGAAGTAAGCCCCCAACCCTAGTTGGGTCTGGACCAACAAGACACGAGGAGGCAGCAGCCCACAGCCGACCCCTCATGCCACG CACTGAGCAGGGTTCCGCATGGACGCTGGTCTTGCCTCCCAGGCGCCTGAACTAGCGGAGTTGGGGTATCGGGTGGAGTCTCGGAGAACC AATCCAATCTGAGGGGGACGCCTGTGGGAGTCCTAAGTATCCAGCGCAGCTGGGAGGCCCACGTTGGGAAGTCGGAGACCGACCCCGCCT CCCGACTGCGCCGACTGCAAGAGAGCGCTTCCGGCGGCGCTTGGAGGCCGAGCAGTTGGGGGCGGGGCTCGTGCTGTGACGCAAGCCTCG CCTCGCCCCGCGCCGCGCGCGTTGCCAGGGTGATCAGGTGACTCCCGGTTCGCGGCGCTGGGAGCGGCCGTGACGTCAGGCGCCCGGCTG CTCCTCACTTGCTCTGAGACAGGTGCGGCAAGTCTACTGCGGGCTGGTCCGGGCTCCTCAGGTTCAGACCCGACCGTTATCCAGTCGGTT CGTGGAGAGGAGAGGTGCACTTTACAGGTCCCCGATGAACCAAGAGAACCCTCCACCATATCCAGGCCCTGGTCCAACGGCCCCATACCC ACCTTATCCACCACAACCAATGGGTCCAGGACCTATGGGGGGACCCTACCCACCTCCTCAAGGGTACCCCTACCAAGGATACCCACAGTA CGGCTGGCAGGGTGGACCTCAGGAGCCTCCTAAAACCACAGCTGGTTTTAGAAAAAGTTTTCGTCTTAGTAGAAAAGATAAGAAAACAAA TAAATCCATGTATGAATGCAAGAAGAGTGATCAGTACGACACAGCTGACGTACCCACATACGAAGAAGTGACACCGTATCGGCGACAAAC TAATGAAAAATACAGACTCGTTGTCTTGGTTGGTCCCGTGGGAGTAGGGCTGAATGAACTGAAACGAAAGCTGCTGATCAGTGACACCCA GCACTATGGCGTGACAGTGCCCCATACCACCAGAGCAAGAAGAAGCCAGGAGAGTGATGGTGTTGAATACATTTTCATTTCCAAGCATTT GTTTGAGACAGATGTACAAAATAACAAGTTTATTGAATATGGAGAATATAAAAACAACTACTACGGCACAAGTATAGACTCAGTTCGGTC TGTCCTTGCTAAAAACAAAGTTTGTTTGTTGGATGTTCAGCCTCATACAGTGAAGCATTTAAGGACACTAGAATTTAAGCCCTATGTGAT ATTTATAAAGCCTCCATCAATAGAGCGTTTGAGAGAAACAAGAAAAAATGCAAAGATTATTTCAAGCAGAGATGACCAAGGTGCTGCAAA ACCCTTCACAGAAGAAGATTTTCAAGAAATGATTAAATCTGCACAGATAATGGAAAGTCAATATGGTCATCTTTTTGACAAAATTATAAT AAATGATGACCTCACTGTGGCATTCAATGAGCTCAAAACAACTTTTGACAAATTAGAGACAGAGACCCATTGGGTGCCAGTGAGCTGGTT ACATTCATAACTAAGAGAAATTTCCATAATTGTCTTTTTCTATAGAGTGCATGATGAAATCAATTACAGTTTTGGTAGTAGGGTTTTTAA ATCTATATCACTGTCATAGATGTACAATCTTGGTTCAAGTTGAATGCTGGTTTTGTTTGTATCTTTTTACAGCCTTATTTCAAACGCCAT GTGTTAGTATAAGATCCGAAATCAAAATATGCACAGTACTGTATTCTAAGCAAAACCTCAAACCTTCTCGTTGTCTTCAATACCGCTCTA TCTCCAAGATGAGGCTGAAATTTTCAGAGAGACTTAGCTAGAGGCTTAGTATGTATGGGAGTTCAGCGCTTCTGCTGGTCTCAGGTGTGG CTGCTGCTGTCGAGTTTGAATGTTAGCTGTTGAAGGTATCAATTCAGCAGCCATGAGCAGCTCCAGACAGACAGGTGAGCTCTGCTGTTT CTGGGTGGATCATCACAGATTTAGCCGGGCAGGCAGTAAGGTGTCCTCTTACTATTCAAAAAGTGTAGACTTTCTTACATATTCGCAATA CGTTCACAGTGTGTGCATTTTAAAATAATTCTTAAAGGAGTAACTGAAATTTTACCTTGAGTGAATGGCCTTCATAATATAGCTTGAGAA GTCCTTTTGAGTACCTGTCAGTGACTCAACAACATTTAATAAGGGAAAGTAGACTTTTAACAGTTATTATATATGTAACGAAAAGCCTTT CCTTTGGGATTAATATAAGTAAGAATGGTAGCCTTGTGGCAAGAAATGATTACAAAGGATATTTTTATTTGTAATTCCTCAGAAGACAAT TTATGAAGTCACCCAAAATGTTATTTTAGCTGGTTTTGGATTTTTCCAATAAATTAGAAGAAGGATTTCTATTCTAAAACATGTAAAACC TGTTTTACATATTACTGATACAATTAAAGATTATTTTTCATCTATGTGCAATAGATCACCCCTCTTTAAATTGCTCTAAGATTTATTTTA GAAAACTTTTCATGTGATGTTATTTCTTTGTCATCAAAATGCTTGTTAACACTGTCCAGACACCATCCTAACCTTGCCATTGTTAAAGAA GTTTAGGAAAGACTCTTATATTGTAAATATTTAGATGGGTTCTCTCACTTTTCTTTGATACTACTGATTTTCAGCAAGTGAATTATATAA TTCAAAATGCTAGAAATGTCTATCCGTTCTATAAGAGAGCATATCCTGCCGTTCTTGCATGCAGTGAAGCCCTGCCCGTCGAAAATCATT GCATCTGTGACTTTCAAAGTGGAAAAAAAAATGTTATTTTTTTGTTGATTTGTAAAGAGAGTTTAAATGTCATGTGAAAAAAAATAGAAT GTAGTAAAATTCTATATATTTATGAAATATTTTAAAGGCATATTTTTTTAAATATCAAACGGGGCTATTCATAAAATAAACTGATTGTAT GTCAAGATGTCCTAATTTAAAAGAGTAGTTTTATAAATCATGGTCAACATTCCATGTAAATATTTGAGCTTTACAAAGATAGATCCAAGT GTGCGATCTGTGCACTGCACATTTGATAGCATTATTCACTGGTTTTCCTTCATACTTGTCAAGTTCATATTAGAAGCAGAGACAAAAACC ACTCCAATGGCCTTGACACATAGTCACACCAAAATAGATAATCAGACTAAGTATTATATAACAACGTGATCCAGACAGTGAGTTCTAAGT GTATTAATTAAATAGCAAAAAATTTTGTTTTTAAAAAATGAAAGAGGGAGGGTTGCCAACCTGAAGTCTTAAGTAGATTGTTTGGGTAGC ATATTTCCTTCTTTGAACATTGTCTGAAATTTTCTATAAATCAAGACTTCTTGTACAAAGAATGATGGGACATATGTAATAATTCAGGCA ATCACCTGAGTAATTTAGGCAGTCCAAATTCTTTACCCTGAAATACCCACATTTTAAAAAAATTGCAGATAATTGCTTCAGTTATTTACT TTGGGGACAGAGATATAGTGTAAAGTGGGAGAAACTGAGTCCTTTTTTGGTGGTGGTAATAATAAGATGTTATAAAAATATAACATTTTA AAAAAGAAAGGTCCAGACCTTAAGCGCAGAGCTAGAACAATATTTTTTAAATAATGGGGGGAAAAGGGGGCACTTTGGTAATTTTAGAAA TCAGGTAGTATACTTTTTTTTTTTTTTTTGAGACAGGGTCTTGCCATGTTGCTCAGGCTGGTCTTGAACTCCTGGGCTCAAGCAATCCTC CTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGATCCACCGTGCCCAGCCGGTAGACGTGGTCTTAAAAACAGTGTTTACATGGC CATCTTGATGCTTAGAAAGATAATTGATTAAAATTTAATAAGGCAGGGCCAACTCCGAGAGTTCATTGACAACGGCAGCAAAAAGGCCCT GAATTCTGTACTTTCTTCCCCCAGCCTCCTTCTCCAGCAAGGAGAATAGCACTCCTCCCTCCAGAAGCCAGCTCCCTAAGTTGGAGCCAC TATGTAAGAGAAGAGGAACGTTCACTTTTTAAAATTCATATATTTAAAAATCAAGACCAAAAAGTAAATTCTGTACTCCTATTATTGACT GTAGTCAATCAAACATAAAAAGGTGAAAGTAAAATTTAATTTTTTACCCTTATTTTACTGACCAATATGGAAGTTCTTGGTATCTTTAAG GCTGACCTTCCTGGTATTGTGTAATGATTGAATGTATCTAAACTGTAATAATTTGAAACTGACAAACATAACCTTCTCAGACTTACAAAA CTATGTTCTTTCTAAAGATACAGATTTTTATTATTTTATTTTGACTAGGAAGGATTTATAAATAAATGTAATGAAAAATCTTTGATCTTA ATAAAGTACCTTCAAACAGTGTGTGTACTTACTTGAAAATTGTTTTTGCACTTGGATATTCTATTTTATTATACTACTATTGTGATCTAT TCCATTATACTATTTCCCATGGTAGAACAAATTATATTTTCTACTGTGATATGAAGTGATGTAATTGAACTTGCCATGTCTAAAATTAAA >21130_21130_1_CYSTM1-MPP7_CYSTM1_chr5_139574237_ENST00000261811_MPP7_chr10_28378770_ENST00000337532_length(amino acids)=358AA_BP=99 MRQVRQVYCGLVRAPQVQTRPLSSRFVERRGALYRSPMNQENPPPYPGPGPTAPYPPYPPQPMGPGPMGGPYPPPQGYPYQGYPQYGWQG GPQEPPKTTAGFRKSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYGV TVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKP -------------------------------------------------------------- >21130_21130_2_CYSTM1-MPP7_CYSTM1_chr5_139574237_ENST00000261811_MPP7_chr10_28378770_ENST00000375719_length(transcript)=1634nt_BP=851nt TACTGGCGGGACTACTTGTTGCAAGGTTTATGGGGAAAAGTAGCCAGAGAGCAATCCAGTTATCAGCCTCAGCCCCATTCCGCTCAGGTA CAGCTCGGGAAGTAAGCCCCCAACCCTAGTTGGGTCTGGACCAACAAGACACGAGGAGGCAGCAGCCCACAGCCGACCCCTCATGCCACG CACTGAGCAGGGTTCCGCATGGACGCTGGTCTTGCCTCCCAGGCGCCTGAACTAGCGGAGTTGGGGTATCGGGTGGAGTCTCGGAGAACC AATCCAATCTGAGGGGGACGCCTGTGGGAGTCCTAAGTATCCAGCGCAGCTGGGAGGCCCACGTTGGGAAGTCGGAGACCGACCCCGCCT CCCGACTGCGCCGACTGCAAGAGAGCGCTTCCGGCGGCGCTTGGAGGCCGAGCAGTTGGGGGCGGGGCTCGTGCTGTGACGCAAGCCTCG CCTCGCCCCGCGCCGCGCGCGTTGCCAGGGTGATCAGGTGACTCCCGGTTCGCGGCGCTGGGAGCGGCCGTGACGTCAGGCGCCCGGCTG CTCCTCACTTGCTCTGAGACAGGTGCGGCAAGTCTACTGCGGGCTGGTCCGGGCTCCTCAGGTTCAGACCCGACCGTTATCCAGTCGGTT CGTGGAGAGGAGAGGTGCACTTTACAGGTCCCCGATGAACCAAGAGAACCCTCCACCATATCCAGGCCCTGGTCCAACGGCCCCATACCC ACCTTATCCACCACAACCAATGGGTCCAGGACCTATGGGGGGACCCTACCCACCTCCTCAAGGGTACCCCTACCAAGGATACCCACAGTA CGGCTGGCAGGGTGGACCTCAGGAGCCTCCTAAAACCACAGCTGGTTTTAGAAAAAGTTTTCGTCTTAGTAGAAAAGATAAGAAAACAAA TAAATCCATGTATGAATGCAAGAAGAGTGATCAGTACGACACAGCTGACGTACCCACATACGAAGAAGTGACACCGTATCGGCGACAAAC TAATGAAAAATACAGACTCGTTGTCTTGGTTGGTCCCGTGGGAGTAGGGCTGAATGAACTGAAACGAAAGCTGCTGATCAGTGACACCCA GCACTATGGCGTGACAGTGCCCCATACCACCAGAGCAAGAAGAAGCCAGGAGAGTGATGGTGTTGAATACATTTTCATTTCCAAGCATTT GTTTGAGACAGATGTACAAAATAACAAGTTTATTGAATATGGAGAATATAAAAACAACTACTACGGCACAAGTATAGACTCAGTTCGGTC TGTCCTTGCTAAAAACAAAGTTTGTTTGTTGGATGTTCAGCCTCATACAGTGAAGCATTTAAGGACACTAGAATTTAAGCCCTATGTGAT ATTTATAAAGCCTCCATCAATAGAGCGTTTGAGAGAAACAAGAAAAAATGCAAAGATTATTTCAAGCAGAGATGACCAAGGTGCTGCAAA ACCCTTCACAGAAGAAGATTTTCAAGAAATGATTAAATCTGCACAGATAATGGAAAGTCAATATGGTCATCTTTTTGACAAAATTATAAT AAATGATGACCTCACTGTGGCATTCAATGAGCTCAAAACAACTTTTGACAAATTAGAGACAGAGACCCATTGGGTGCCAGTGAGCTGGTT >21130_21130_2_CYSTM1-MPP7_CYSTM1_chr5_139574237_ENST00000261811_MPP7_chr10_28378770_ENST00000375719_length(amino acids)=358AA_BP=99 MRQVRQVYCGLVRAPQVQTRPLSSRFVERRGALYRSPMNQENPPPYPGPGPTAPYPPYPPQPMGPGPMGGPYPPPQGYPYQGYPQYGWQG GPQEPPKTTAGFRKSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYGV TVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKP -------------------------------------------------------------- >21130_21130_3_CYSTM1-MPP7_CYSTM1_chr5_139574237_ENST00000261811_MPP7_chr10_28378770_ENST00000375732_length(transcript)=4702nt_BP=851nt TACTGGCGGGACTACTTGTTGCAAGGTTTATGGGGAAAAGTAGCCAGAGAGCAATCCAGTTATCAGCCTCAGCCCCATTCCGCTCAGGTA CAGCTCGGGAAGTAAGCCCCCAACCCTAGTTGGGTCTGGACCAACAAGACACGAGGAGGCAGCAGCCCACAGCCGACCCCTCATGCCACG CACTGAGCAGGGTTCCGCATGGACGCTGGTCTTGCCTCCCAGGCGCCTGAACTAGCGGAGTTGGGGTATCGGGTGGAGTCTCGGAGAACC AATCCAATCTGAGGGGGACGCCTGTGGGAGTCCTAAGTATCCAGCGCAGCTGGGAGGCCCACGTTGGGAAGTCGGAGACCGACCCCGCCT CCCGACTGCGCCGACTGCAAGAGAGCGCTTCCGGCGGCGCTTGGAGGCCGAGCAGTTGGGGGCGGGGCTCGTGCTGTGACGCAAGCCTCG CCTCGCCCCGCGCCGCGCGCGTTGCCAGGGTGATCAGGTGACTCCCGGTTCGCGGCGCTGGGAGCGGCCGTGACGTCAGGCGCCCGGCTG CTCCTCACTTGCTCTGAGACAGGTGCGGCAAGTCTACTGCGGGCTGGTCCGGGCTCCTCAGGTTCAGACCCGACCGTTATCCAGTCGGTT CGTGGAGAGGAGAGGTGCACTTTACAGGTCCCCGATGAACCAAGAGAACCCTCCACCATATCCAGGCCCTGGTCCAACGGCCCCATACCC ACCTTATCCACCACAACCAATGGGTCCAGGACCTATGGGGGGACCCTACCCACCTCCTCAAGGGTACCCCTACCAAGGATACCCACAGTA CGGCTGGCAGGGTGGACCTCAGGAGCCTCCTAAAACCACAGCTGGTTTTAGAAAAAGTTTTCGTCTTAGTAGAAAAGATAAGAAAACAAA TAAATCCATGTATGAATGCAAGAAGAGTGATCAGTACGACACAGCTGACGTACCCACATACGAAGAAGTGACACCGTATCGGCGACAAAC TAATGAAAAATACAGACTCGTTGTCTTGGTTGGTCCCGTGGGAGTAGGGCTGAATGAACTGAAACGAAAGCTGCTGATCAGTGACACCCA GCACTATGGCGTGACAGTGCCCCATACCACCAGAGCAAGAAGAAGCCAGGAGAGTGATGGTGTTGAATACATTTTCATTTCCAAGCATTT GTTTGAGACAGATGTACAAAATAACAAGTTTATTGAATATGGAGAATATAAAAACAACTACTACGGCACAAGTATAGACTCAGTTCGGTC TGTCCTTGCTAAAAACAAAGTTTGTTTGTTGGATGTTCAGCCTCATACAGTGAAGCATTTAAGGACACTAGAATTTAAGCCCTATGTGAT ATTTATAAAGCCTCCATCAATAGAGCGTTTGAGAGAAACAAGAAAAAATGCAAAGATTATTTCAAGCAGAGATGACCAAGGTGCTGCAAA ACCCTTCACAGAAGAAGATTTTCAAGAAATGATTAAATCTGCACAGATAATGGAAAGTCAATATGGTCATCTTTTTGACAAAATTATAAT AAATGATGACCTCACTGTGGCATTCAATGAGCTCAAAACAACTTTTGACAAATTAGAGACAGAGACCCATTGGGTGCCAGTGAGCTGGTT ACATTCATAACTAAGAGAAATTTCCATAATTGTCTTTTTCTATAGAGTGCATGATGAAATCAATTACAGTTTTGGTAGTAGGGTTTTTAA ATCTATATCACTGTCATAGATGTACAATCTTGGTTCAAGTTGAATGCTGGTTTTGTTTGTATCTTTTTACAGCCTTATTTCAAACGCCAT GTGTTAGTATAAGATCCGAAATCAAAATATGCACAGTACTGTATTCTAAGCAAAACCTCAAACCTTCTCGTTGTCTTCAATACCGCTCTA TCTCCAAGATGAGGCTGAAATTTTCAGAGAGACTTAGCTAGAGGCTTAGTATGTATGGGAGTTCAGCGCTTCTGCTGGTCTCAGGTGTGG CTGCTGCTGTCGAGTTTGAATGTTAGCTGTTGAAGGTATCAATTCAGCAGCCATGAGCAGCTCCAGACAGACAGGTGAGCTCTGCTGTTT CTGGGTGGATCATCACAGATTTAGCCGGGCAGGCAGTAAGGTGTCCTCTTACTATTCAAAAAGTGTAGACTTTCTTACATATTCGCAATA CGTTCACAGTGTGTGCATTTTAAAATAATTCTTAAAGGAGTAACTGAAATTTTACCTTGAGTGAATGGCCTTCATAATATAGCTTGAGAA GTCCTTTTGAGTACCTGTCAGTGACTCAACAACATTTAATAAGGGAAAGTAGACTTTTAACAGTTATTATATATGTAACGAAAAGCCTTT CCTTTGGGATTAATATAAGTAAGAATGGTAGCCTTGTGGCAAGAAATGATTACAAAGGATATTTTTATTTGTAATTCCTCAGAAGACAAT TTATGAAGTCACCCAAAATGTTATTTTAGCTGGTTTTGGATTTTTCCAATAAATTAGAAGAAGGATTTCTATTCTAAAACATGTAAAACC TGTTTTACATATTACTGATACAATTAAAGATTATTTTTCATCTATGTGCAATAGATCACCCCTCTTTAAATTGCTCTAAGATTTATTTTA GAAAACTTTTCATGTGATGTTATTTCTTTGTCATCAAAATGCTTGTTAACACTGTCCAGACACCATCCTAACCTTGCCATTGTTAAAGAA GTTTAGGAAAGACTCTTATATTGTAAATATTTAGATGGGTTCTCTCACTTTTCTTTGATACTACTGATTTTCAGCAAGTGAATTATATAA TTCAAAATGCTAGAAATGTCTATCCGTTCTATAAGAGAGCATATCCTGCCGTTCTTGCATGCAGTGAAGCCCTGCCCGTCGAAAATCATT GCATCTGTGACTTTCAAAGTGGAAAAAAAAATGTTATTTTTTTGTTGATTTGTAAAGAGAGTTTAAATGTCATGTGAAAAAAAATAGAAT GTAGTAAAATTCTATATATTTATGAAATATTTTAAAGGCATATTTTTTTAAATATCAAACGGGGCTATTCATAAAATAAACTGATTGTAT GTCAAGATGTCCTAATTTAAAAGAGTAGTTTTATAAATCATGGTCAACATTCCATGTAAATATTTGAGCTTTACAAAGATAGATCCAAGT GTGCGATCTGTGCACTGCACATTTGATAGCATTATTCACTGGTTTTCCTTCATACTTGTCAAGTTCATATTAGAAGCAGAGACAAAAACC ACTCCAATGGCCTTGACACATAGTCACACCAAAATAGATAATCAGACTAAGTATTATATAACAACGTGATCCAGACAGTGAGTTCTAAGT GTATTAATTAAATAGCAAAAAATTTTGTTTTTAAAAAATGAAAGAGGGAGGGTTGCCAACCTGAAGTCTTAAGTAGATTGTTTGGGTAGC ATATTTCCTTCTTTGAACATTGTCTGAAATTTTCTATAAATCAAGACTTCTTGTACAAAGAATGATGGGACATATGTAATAATTCAGGCA ATCACCTGAGTAATTTAGGCAGTCCAAATTCTTTACCCTGAAATACCCACATTTTAAAAAAATTGCAGATAATTGCTTCAGTTATTTACT TTGGGGACAGAGATATAGTGTAAAGTGGGAGAAACTGAGTCCTTTTTTGGTGGTGGTAATAATAAGATGTTATAAAAATATAACATTTTA AAAAAGAAAGGTCCAGACCTTAAGCGCAGAGCTAGAACAATATTTTTTAAATAATGGGGGGAAAAGGGGGCACTTTGGTAATTTTAGAAA TCAGGTAGTATACTTTTTTTTTTTTTTTTGAGACAGGGTCTTGCCATGTTGCTCAGGCTGGTCTTGAACTCCTGGGCTCAAGCAATCCTC CTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGATCCACCGTGCCCAGCCGGTAGACGTGGTCTTAAAAACAGTGTTTACATGGC CATCTTGATGCTTAGAAAGATAATTGATTAAAATTTAATAAGGCAGGGCCAACTCCGAGAGTTCATTGACAACGGCAGCAAAAAGGCCCT GAATTCTGTACTTTCTTCCCCCAGCCTCCTTCTCCAGCAAGGAGAATAGCACTCCTCCCTCCAGAAGCCAGCTCCCTAAGTTGGAGCCAC TATGTAAGAGAAGAGGAACGTTCACTTTTTAAAATTCATATATTTAAAAATCAAGACCAAAAAGTAAATTCTGTACTCCTATTATTGACT GTAGTCAATCAAACATAAAAAGGTGAAAGTAAAATTTAATTTTTTACCCTTATTTTACTGACCAATATGGAAGTTCTTGGTATCTTTAAG GCTGACCTTCCTGGTATTGTGTAATGATTGAATGTATCTAAACTGTAATAATTTGAAACTGACAAACATAACCTTCTCAGACTTACAAAA CTATGTTCTTTCTAAAGATACAGATTTTTATTATTTTATTTTGACTAGGAAGGATTTATAAATAAATGTAATGAAAAATCTTTGATCTTA ATAAAGTACCTTCAAACAGTGTGTGTACTTACTTGAAAATTGTTTTTGCACTTGGATATTCTATTTTATTATACTACTATTGTGATCTAT TCCATTATACTATTTCCCATGGTAGAACAAATTATATTTTCTACTGTGATATGAAGTGATGTAATTGAACTTGCCATGTCTAAAATTAAA >21130_21130_3_CYSTM1-MPP7_CYSTM1_chr5_139574237_ENST00000261811_MPP7_chr10_28378770_ENST00000375732_length(amino acids)=358AA_BP=99 MRQVRQVYCGLVRAPQVQTRPLSSRFVERRGALYRSPMNQENPPPYPGPGPTAPYPPYPPQPMGPGPMGGPYPPPQGYPYQGYPQYGWQG GPQEPPKTTAGFRKSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYGV TVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKP -------------------------------------------------------------- >21130_21130_4_CYSTM1-MPP7_CYSTM1_chr5_139574237_ENST00000261811_MPP7_chr10_28378770_ENST00000445954_length(transcript)=1537nt_BP=851nt TACTGGCGGGACTACTTGTTGCAAGGTTTATGGGGAAAAGTAGCCAGAGAGCAATCCAGTTATCAGCCTCAGCCCCATTCCGCTCAGGTA CAGCTCGGGAAGTAAGCCCCCAACCCTAGTTGGGTCTGGACCAACAAGACACGAGGAGGCAGCAGCCCACAGCCGACCCCTCATGCCACG CACTGAGCAGGGTTCCGCATGGACGCTGGTCTTGCCTCCCAGGCGCCTGAACTAGCGGAGTTGGGGTATCGGGTGGAGTCTCGGAGAACC AATCCAATCTGAGGGGGACGCCTGTGGGAGTCCTAAGTATCCAGCGCAGCTGGGAGGCCCACGTTGGGAAGTCGGAGACCGACCCCGCCT CCCGACTGCGCCGACTGCAAGAGAGCGCTTCCGGCGGCGCTTGGAGGCCGAGCAGTTGGGGGCGGGGCTCGTGCTGTGACGCAAGCCTCG CCTCGCCCCGCGCCGCGCGCGTTGCCAGGGTGATCAGGTGACTCCCGGTTCGCGGCGCTGGGAGCGGCCGTGACGTCAGGCGCCCGGCTG CTCCTCACTTGCTCTGAGACAGGTGCGGCAAGTCTACTGCGGGCTGGTCCGGGCTCCTCAGGTTCAGACCCGACCGTTATCCAGTCGGTT CGTGGAGAGGAGAGGTGCACTTTACAGGTCCCCGATGAACCAAGAGAACCCTCCACCATATCCAGGCCCTGGTCCAACGGCCCCATACCC ACCTTATCCACCACAACCAATGGGTCCAGGACCTATGGGGGGACCCTACCCACCTCCTCAAGGGTACCCCTACCAAGGATACCCACAGTA CGGCTGGCAGGGTGGACCTCAGGAGCCTCCTAAAACCACAGCTGGTTTTAGAAAAAGTTTTCGTCTTAGTAGAAAAGATAAGAAAACAAA TAAATCCATGTATGAATGCAAGAAGAGTGATCAGTACGACACAGCTGACGTACCCACATACGAAGAAGTGACACCGTATCGGCGACAAAC TAATGAAAAATACAGACTCGTTGTCTTGGTTGGTCCCGTGGGAGTAGGGCTGAATGAACTGAAACGAAAGCTGCTGATCAGTGACACCCA GCACTATGGCGTGACAGTGCCCCATACCACCAGAGCAAGAAGAAGCCAGGAGAGTGATGGTGTTGAATACATTTTCATTTCCAAGCATTT GTTTGAGACAGATGTACAAAATAACAAGTTTATTGAATATGGAGAATATAAAAACAACTACTACGGCACAAGTATAGACTCAGTTCGGTC TGTCCTTGCTAAAAACAAAGTTTGTTTGTTGGATGTTCAGCCTCATGGACCATGGTTTCTCCTTCCACTGATGGCTGTACCCTGGGGTGC AAAACCTCCAAATGCTAGAATGACCTGCGGAAGCCCTTTGGACCTCTAAAGGAAGATGAATCTGGAGTAAAAGTGTTTCAAGAATCAGGA AGGCTGCCTCCTGACTTGGGCACTGTGTTAGTCCCTTGTTGCACTGCTCTGAAGAAATACCTGAAACTGGACAGTGAAGCATTTAAGGAC >21130_21130_4_CYSTM1-MPP7_CYSTM1_chr5_139574237_ENST00000261811_MPP7_chr10_28378770_ENST00000445954_length(amino acids)=281AA_BP=99 MRQVRQVYCGLVRAPQVQTRPLSSRFVERRGALYRSPMNQENPPPYPGPGPTAPYPPYPPQPMGPGPMGGPYPPPQGYPYQGYPQYGWQG GPQEPPKTTAGFRKSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYGV TVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHGPWFLLPLMAVPWGAKPPN -------------------------------------------------------------- >21130_21130_5_CYSTM1-MPP7_CYSTM1_chr5_139574237_ENST00000261811_MPP7_chr10_28378770_ENST00000540098_length(transcript)=4526nt_BP=851nt TACTGGCGGGACTACTTGTTGCAAGGTTTATGGGGAAAAGTAGCCAGAGAGCAATCCAGTTATCAGCCTCAGCCCCATTCCGCTCAGGTA CAGCTCGGGAAGTAAGCCCCCAACCCTAGTTGGGTCTGGACCAACAAGACACGAGGAGGCAGCAGCCCACAGCCGACCCCTCATGCCACG CACTGAGCAGGGTTCCGCATGGACGCTGGTCTTGCCTCCCAGGCGCCTGAACTAGCGGAGTTGGGGTATCGGGTGGAGTCTCGGAGAACC AATCCAATCTGAGGGGGACGCCTGTGGGAGTCCTAAGTATCCAGCGCAGCTGGGAGGCCCACGTTGGGAAGTCGGAGACCGACCCCGCCT CCCGACTGCGCCGACTGCAAGAGAGCGCTTCCGGCGGCGCTTGGAGGCCGAGCAGTTGGGGGCGGGGCTCGTGCTGTGACGCAAGCCTCG CCTCGCCCCGCGCCGCGCGCGTTGCCAGGGTGATCAGGTGACTCCCGGTTCGCGGCGCTGGGAGCGGCCGTGACGTCAGGCGCCCGGCTG CTCCTCACTTGCTCTGAGACAGGTGCGGCAAGTCTACTGCGGGCTGGTCCGGGCTCCTCAGGTTCAGACCCGACCGTTATCCAGTCGGTT CGTGGAGAGGAGAGGTGCACTTTACAGGTCCCCGATGAACCAAGAGAACCCTCCACCATATCCAGGCCCTGGTCCAACGGCCCCATACCC ACCTTATCCACCACAACCAATGGGTCCAGGACCTATGGGGGGACCCTACCCACCTCCTCAAGGGTACCCCTACCAAGGATACCCACAGTA CGGCTGGCAGGGTGGACCTCAGGAGCCTCCTAAAACCACAGCTGGTTTTAGAAAAAGTTTTCGTCTTAGTAGAAAAGATAAGAAAACAAA TAAATCCATGTATGAATGCAAGAAGAGTGATCAGTACGACACAGCTGACGTACCCACATACGAAGAAGTGACACCGTATCGGCGACAAAC TAATGAAAAATACAGACTCGTTGTCTTGGTTGGTCCCGTGGGAGTAGGGCTGAATGAACTGAAACGAAAGCTGCTGATCAGTGACACCCA GCACTATGGCGTGACAGTGCCCCATACCACCAGAGCAAGAAGAAGCCAGGAGAGTGATGGTGTTGAATACATTTTCATTTCCAAGCATTT GTTTGAGACAGATGTACAAAATAACAAGTTTATTGAATATGGAGAATATAAAAACAACTACTACGGCACAAGTATAGACTCAGTTCGGTC TGTCCTTGCTAAAAACAAAGTTTGTTTGTTGGATGTTCAGCCTCATACAGTGAAGCATTTAAGGACACTAGAATTTAAGCCCTATGTGAT ATTTATAAAGCCTCCATCAATAGAGCGTTTGAGAGAAACAAGAAAAAATGCAAAGATTATTTCAAGCAGAGATGACCAAGGTGCTGCAAA ACCCTTCACAGAAGAAGATTTTCAAGAAATGATTAAATCTGCACAGATAATGGAAAGTCAATATGGTCATCTTTTTGACAAAATTATAAT AAATGATGACCTCACTGTGGCATTCAATGAGCTCAAAACAACTTTTGACAAATTAGAGACAGAGACCCATTGGGTGCCAGTGAGCTGGTT ACATTCATAACTAAGAGAAATTTCCATAATTGTCTTTTTCTATAGAGTGCATGATGAAATCAATTACAGTTTTGGTAGTAGGGTTTTTAA ATCTATATCACTGTCATAGATGTACAATCTTGGTTCAAGTTGAATGCTGGTTTTGTTTGTATCTTTTTACAGCCTTATTTCAAACGCCAT GTGTTAGTATAAGATCCGAAATCAAAATATGCACAGTACTGTATTCTAAGCAAAACCTCAAACCTTCTCGTTGTCTTCAATACCGCTCTA TCTCCAAGATGAGGCTGAAATTTTCAGAGAGACTTAGCTAGAGGCTTAGTATGTATGGGAGTTCAGCGCTTCTGCTGGTCTCAGGTGTGG CTGCTGCTGTCGAGTTTGAATGTTAGCTGTTGAAGGTATCAATTCAGCAGCCATGAGCAGCTCCAGACAGACAGGTGAGCTCTGCTGTTT CTGGGTGGATCATCACAGATTTAGCCGGGCAGGCAGTAAGGTGTCCTCTTACTATTCAAAAAGTGTAGACTTTCTTACATATTCGCAATA CGTTCACAGTGTGTGCATTTTAAAATAATTCTTAAAGGAGTAACTGAAATTTTACCTTGAGTGAATGGCCTTCATAATATAGCTTGAGAA GTCCTTTTGAGTACCTGTCAGTGACTCAACAACATTTAATAAGGGAAAGTAGACTTTTAACAGTTATTATATATGTAACGAAAAGCCTTT CCTTTGGGATTAATATAAGTAAGAATGGTAGCCTTGTGGCAAGAAATGATTACAAAGGATATTTTTATTTGTAATTCCTCAGAAGACAAT TTATGAAGTCACCCAAAATGTTATTTTAGCTGGTTTTGGATTTTTCCAATAAATTAGAAGAAGGATTTCTATTCTAAAACATGTAAAACC TGTTTTACATATTACTGATACAATTAAAGATTATTTTTCATCTATGTGCAATAGATCACCCCTCTTTAAATTGCTCTAAGATTTATTTTA GAAAACTTTTCATGTGATGTTATTTCTTTGTCATCAAAATGCTTGTTAACACTGTCCAGACACCATCCTAACCTTGCCATTGTTAAAGAA GTTTAGGAAAGACTCTTATATTGTAAATATTTAGATGGGTTCTCTCACTTTTCTTTGATACTACTGATTTTCAGCAAGTGAATTATATAA TTCAAAATGCTAGAAATGTCTATCCGTTCTATAAGAGAGCATATCCTGCCGTTCTTGCATGCAGTGAAGCCCTGCCCGTCGAAAATCATT GCATCTGTGACTTTCAAAGTGGAAAAAAAAATGTTATTTTTTTGTTGATTTGTAAAGAGAGTTTAAATGTCATGTGAAAAAAAATAGAAT GTAGTAAAATTCTATATATTTATGAAATATTTTAAAGGCATATTTTTTTAAATATCAAACGGGGCTATTCATAAAATAAACTGATTGTAT GTCAAGATGTCCTAATTTAAAAGAGTAGTTTTATAAATCATGGTCAACATTCCATGTAAATATTTGAGCTTTACAAAGATAGATCCAAGT GTGCGATCTGTGCACTGCACATTTGATAGCATTATTCACTGGTTTTCCTTCATACTTGTCAAGTTCATATTAGAAGCAGAGACAAAAACC ACTCCAATGGCCTTGACACATAGTCACACCAAAATAGATAATCAGACTAAGTATTATATAACAACGTGATCCAGACAGTGAGTTCTAAGT GTATTAATTAAATAGCAAAAAATTTTGTTTTTAAAAAATGAAAGAGGGAGGGTTGCCAACCTGAAGTCTTAAGTAGATTGTTTGGGTAGC ATATTTCCTTCTTTGAACATTGTCTGAAATTTTCTATAAATCAAGACTTCTTGTACAAAGAATGATGGGACATATGTAATAATTCAGGCA ATCACCTGAGTAATTTAGGCAGTCCAAATTCTTTACCCTGAAATACCCACATTTTAAAAAAATTGCAGATAATTGCTTCAGTTATTTACT TTGGGGACAGAGATATAGTGTAAAGTGGGAGAAACTGAGTCCTTTTTTGGTGGTGGTAATAATAAGATGTTATAAAAATATAACATTTTA AAAAAGAAAGGTCCAGACCTTAAGCGCAGAGCTAGAACAATATTTTTTAAATAATGGGGGGAAAAGGGGGCACTTTGGTAATTTTAGAAA TCAGGTAGTATACTTTTTTTTTTTTTTTTGAGACAGGGTCTTGCCATGTTGCTCAGGCTGGTCTTGAACTCCTGGGCTCAAGCAATCCTC CTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGATCCACCGTGCCCAGCCGGTAGACGTGGTCTTAAAAACAGTGTTTACATGGC CATCTTGATGCTTAGAAAGATAATTGATTAAAATTTAATAAGGCAGGGCCAACTCCGAGAGTTCATTGACAACGGCAGCAAAAAGGCCCT GAATTCTGTACTTTCTTCCCCCAGCCTCCTTCTCCAGCAAGGAGAATAGCACTCCTCCCTCCAGAAGCCAGCTCCCTAAGTTGGAGCCAC TATGTAAGAGAAGAGGAACGTTCACTTTTTAAAATTCATATATTTAAAAATCAAGACCAAAAAGTAAATTCTGTACTCCTATTATTGACT GTAGTCAATCAAACATAAAAAGGTGAAAGTAAAATTTAATTTTTTACCCTTATTTTACTGACCAATATGGAAGTTCTTGGTATCTTTAAG GCTGACCTTCCTGGTATTGTGTAATGATTGAATGTATCTAAACTGTAATAATTTGAAACTGACAAACATAACCTTCTCAGACTTACAAAA CTATGTTCTTTCTAAAGATACAGATTTTTATTATTTTATTTTGACTAGGAAGGATTTATAAATAAATGTAATGAAAAATCTTTGATCTTA >21130_21130_5_CYSTM1-MPP7_CYSTM1_chr5_139574237_ENST00000261811_MPP7_chr10_28378770_ENST00000540098_length(amino acids)=358AA_BP=99 MRQVRQVYCGLVRAPQVQTRPLSSRFVERRGALYRSPMNQENPPPYPGPGPTAPYPPYPPQPMGPGPMGGPYPPPQGYPYQGYPQYGWQG GPQEPPKTTAGFRKSFRLSRKDKKTNKSMYECKKSDQYDTADVPTYEEVTPYRRQTNEKYRLVVLVGPVGVGLNELKRKLLISDTQHYGV TVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSVLAKNKVCLLDVQPHTVKHLRTLEFKPYVIFIKP -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for CYSTM1-MPP7 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for CYSTM1-MPP7 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for CYSTM1-MPP7 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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