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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DAP-CCT5 (FusionGDB2 ID:21336)

Fusion Gene Summary for DAP-CCT5

check button Fusion gene summary
Fusion gene informationFusion gene name: DAP-CCT5
Fusion gene ID: 21336
HgeneTgene
Gene symbol

DAP

CCT5

Gene ID

23549

22948

Gene nameaspartyl aminopeptidasechaperonin containing TCP1 subunit 5
SynonymsASPEP|DAPCCT-epsilon|CCTE|HEL-S-69|PNAS-102|TCP-1-epsilon
Cytomap

2q35

5p15.2

Type of geneprotein-codingprotein-coding
Descriptionaspartyl aminopeptidaseT-complex protein 1 subunit epsilonchaperonin containing TCP1, subunit 5 (epsilon)epididymis secretory protein Li 69
Modification date2020032720200313
UniProtAcc

P51397

P48643

Ensembl transtripts involved in fusion geneENST00000510546, ENST00000230895, 
ENST00000432074, 		ENST00000280326, 
ENST00000503026, ENST00000506600, 
ENST00000515390, ENST00000515676, 
Fusion gene scores* DoF score10 X 8 X 8=64058 X 14 X 17=13804
# samples 1361
** MAII scorelog2(13/640*10)=-2.29956028185891
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(61/13804*10)=-4.50013332598527
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DAP [Title/Abstract] AND CCT5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDAP(10748287)-CCT5(10258223), # samples:2
Anticipated loss of major functional domain due to fusion event.DAP-CCT5 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
DAP-CCT5 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across DAP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CCT5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-BT-A20W-01ADAPchr5

10748287

-CCT5chr5

10256067

+
ChimerDB4BLCATCGA-BT-A20W-01ADAPchr5

10748287

-CCT5chr5

10258223

+


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Fusion Gene ORF analysis for DAP-CCT5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000510546ENST00000280326DAPchr5

10748287

-CCT5chr5

10256067

+
5UTR-3CDSENST00000510546ENST00000280326DAPchr5

10748287

-CCT5chr5

10258223

+
5UTR-3CDSENST00000510546ENST00000503026DAPchr5

10748287

-CCT5chr5

10256067

+
5UTR-3CDSENST00000510546ENST00000503026DAPchr5

10748287

-CCT5chr5

10258223

+
5UTR-3CDSENST00000510546ENST00000506600DAPchr5

10748287

-CCT5chr5

10256067

+
5UTR-3CDSENST00000510546ENST00000506600DAPchr5

10748287

-CCT5chr5

10258223

+
5UTR-3CDSENST00000510546ENST00000515390DAPchr5

10748287

-CCT5chr5

10256067

+
5UTR-3CDSENST00000510546ENST00000515390DAPchr5

10748287

-CCT5chr5

10258223

+
5UTR-3CDSENST00000510546ENST00000515676DAPchr5

10748287

-CCT5chr5

10256067

+
5UTR-3CDSENST00000510546ENST00000515676DAPchr5

10748287

-CCT5chr5

10258223

+
Frame-shiftENST00000230895ENST00000280326DAPchr5

10748287

-CCT5chr5

10256067

+
Frame-shiftENST00000230895ENST00000503026DAPchr5

10748287

-CCT5chr5

10256067

+
Frame-shiftENST00000230895ENST00000506600DAPchr5

10748287

-CCT5chr5

10256067

+
Frame-shiftENST00000230895ENST00000515390DAPchr5

10748287

-CCT5chr5

10256067

+
Frame-shiftENST00000230895ENST00000515676DAPchr5

10748287

-CCT5chr5

10256067

+
Frame-shiftENST00000432074ENST00000280326DAPchr5

10748287

-CCT5chr5

10256067

+
Frame-shiftENST00000432074ENST00000503026DAPchr5

10748287

-CCT5chr5

10256067

+
Frame-shiftENST00000432074ENST00000506600DAPchr5

10748287

-CCT5chr5

10256067

+
Frame-shiftENST00000432074ENST00000515390DAPchr5

10748287

-CCT5chr5

10256067

+
Frame-shiftENST00000432074ENST00000515676DAPchr5

10748287

-CCT5chr5

10256067

+
In-frameENST00000230895ENST00000280326DAPchr5

10748287

-CCT5chr5

10258223

+
In-frameENST00000230895ENST00000503026DAPchr5

10748287

-CCT5chr5

10258223

+
In-frameENST00000230895ENST00000506600DAPchr5

10748287

-CCT5chr5

10258223

+
In-frameENST00000230895ENST00000515390DAPchr5

10748287

-CCT5chr5

10258223

+
In-frameENST00000230895ENST00000515676DAPchr5

10748287

-CCT5chr5

10258223

+
In-frameENST00000432074ENST00000280326DAPchr5

10748287

-CCT5chr5

10258223

+
In-frameENST00000432074ENST00000503026DAPchr5

10748287

-CCT5chr5

10258223

+
In-frameENST00000432074ENST00000506600DAPchr5

10748287

-CCT5chr5

10258223

+
In-frameENST00000432074ENST00000515390DAPchr5

10748287

-CCT5chr5

10258223

+
In-frameENST00000432074ENST00000515676DAPchr5

10748287

-CCT5chr5

10258223

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000230895DAPchr510748287-ENST00000280326CCT5chr510258223+30813562041451415
ENST00000230895DAPchr510748287-ENST00000503026CCT5chr510258223+17473562041451415
ENST00000230895DAPchr510748287-ENST00000515390CCT5chr510258223+15943562041451415
ENST00000230895DAPchr510748287-ENST00000515676CCT5chr510258223+15713562041451415
ENST00000230895DAPchr510748287-ENST00000506600CCT5chr510258223+16803562041451415
ENST00000432074DAPchr510748287-ENST00000280326CCT5chr510258223+30373121601407415
ENST00000432074DAPchr510748287-ENST00000503026CCT5chr510258223+17033121601407415
ENST00000432074DAPchr510748287-ENST00000515390CCT5chr510258223+15503121601407415
ENST00000432074DAPchr510748287-ENST00000515676CCT5chr510258223+15273121601407415
ENST00000432074DAPchr510748287-ENST00000506600CCT5chr510258223+16363121601407415

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000230895ENST00000280326DAPchr510748287-CCT5chr510258223+0.0007874820.9992125
ENST00000230895ENST00000503026DAPchr510748287-CCT5chr510258223+0.001984350.99801564
ENST00000230895ENST00000515390DAPchr510748287-CCT5chr510258223+0.0034141170.99658585
ENST00000230895ENST00000515676DAPchr510748287-CCT5chr510258223+0.0039099460.99609
ENST00000230895ENST00000506600DAPchr510748287-CCT5chr510258223+0.0025091520.9974909
ENST00000432074ENST00000280326DAPchr510748287-CCT5chr510258223+0.0007628920.9992372
ENST00000432074ENST00000503026DAPchr510748287-CCT5chr510258223+0.0017569480.9982431
ENST00000432074ENST00000515390DAPchr510748287-CCT5chr510258223+0.0030397320.9969602
ENST00000432074ENST00000515676DAPchr510748287-CCT5chr510258223+0.0034410560.99655896
ENST00000432074ENST00000506600DAPchr510748287-CCT5chr510258223+0.0021942140.9978058

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Fusion Genomic Features for DAP-CCT5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DAPchr510748286-CCT5chr510258222+3.91E-091
DAPchr510748286-CCT5chr510256066+1.45E-091
DAPchr510748286-CCT5chr510258222+3.91E-091
DAPchr510748286-CCT5chr510256066+1.45E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for DAP-CCT5


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:10748287/chr5:10258223)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DAP

P51397

CCT5

P48643

FUNCTION: Negative regulator of autophagy. Involved in mediating interferon-gamma-induced cell death. {ECO:0000269|PubMed:20537536}.FUNCTION: Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444). The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444). As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638). The TRiC complex plays a role in the folding of actin and tubulin (Probable). {ECO:0000269|PubMed:20080638, ECO:0000269|PubMed:25467444, ECO:0000305}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for DAP-CCT5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>21336_21336_1_DAP-CCT5_DAP_chr5_10748287_ENST00000230895_CCT5_chr5_10258223_ENST00000280326_length(transcript)=3081nt_BP=356nt
GGCTGCGCCACGTCGGCGCGCGGCGGCCGCGCCCCCTTAACGGCAGTGGCACTCACCCGGCTCGCGCGGCCCCGGCGCCCCACGCGCGCG
CGTCGTTCTCCCGCCCGCTCGCTCCCCGGCGCTCACACCTGAGCTCACTCGCGCACGCCCGCCCGGCCCGAGAACCGCGCCGCCGCCTCG
GCCCCGCGGAAGCCCCGCCGCGTCATGTCTTCGCCTCCCGAAGGGAAACTAGAGACTAAAGCTGGACACCCGCCCGCCGTGAAAGCTGGT
GGAATGCGAATTGTGCAGAAACACCCACATACAGGAGACACCAAAGAAGAGAAAGACAAGGATGACCAGGAATGGGAAAGCCCCAGGGTC
AACAGTTGTCACCGACAGATGGCTGAGATTGCTGTGAATGCCGTCCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTT
ATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAGGACACTAAACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAG
ATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATTCTCACATGTCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTG
ACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATACGAAAAGGAGAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAAC
CTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCAAATCACTTACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCT
GAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGGATCGTCCCCAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTT
GTACAGGAGATCTCATTTGGGACAACTAAGGATAAAATGCTGGTCATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGA
GGAGGAAATAAGATGATCATTGAGGAGGCGAAACGATCCCTTCACGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTG
GTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCCCTGGCAGTTAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATG
AGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATGGCCCTCTCTGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGA
GCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGCATCGACTGTTTGCACAAGGGGACAAATGATATGAAGCAACAGCATGTCATAGAA
ACCTTGATTGGCAAAAAGCAACAGATATCTCTTGCAACACAAATGGTTAGAATGATTTTGAAGATTGATGACATTCGTAAGCCTGGAGAA
TCTGAAGAATGAAGACATTGAGAAAACTATGTAGCAAGATCCACTTCTGTGATTAAGTAAATGGATGTCTCGTGATGCATCTACAGTTAT
TTATTGTTACATCCTTTTCCAGACACTGTAGATGCTATAATAAAAATAGCTGTTTGGTAACCATAGTTTCACTTGTTCAAAGCTGTGTAA
TCGTGGGGGTACCATCTCAACTGCTTTTGTATTCATTGTATTAAAAGAATCTGTTTAAACAACCTTTATCTTCTCTTCGGGTTTAAGAAA
CGTTTATTGTAACAGTAATTAAATGCTGCCTTAATTGAAGGGGTTTGGGTGGATTTTTTTTTCTCAAAATAAGCTGTAGGGACTATTTTA
ACAGCTTAAACAGGAGCTCTCAAGATGCACTTTCATATTGAGAGGAATATGGGCTTGATCCTCTTCCTATCTAAATGGGTGGGCCATTTG
ATTGTAGAGGGTCCACCACAGAATTATGGGATGCCTTAAGTGCTGTTACTAGGTTGCTCACAGCCTAACCTGGCGTGTTGTTTAGGGCTG
ATGGAGACCCATGTGAGCCTTTGCTTTCCTCTGGCCCCGGCCCCACCCTGAACACAGCTCATACACAGAATCAGGACCAGCATGTGCAGA
GCTGGCCACCAGCACAGGCTTAGGGCAGTTCAGAACCCACTTGTTTCCCTATCAGAGGGACACAGTGAAGTGGAGGTTAAAGTAAATTAC
AGGAAATAAGGGAGAAATCTTGCAGTTACCATGTTCAGATAGAGTGACTGAAATTAATTGTACTTACTAAAGTATTAACTAGCTAACAGT
GATGGGCCAAGACGCTCCGAGAACTCTACCGGGATTGTCTGTTCTGACAACCCAGTGAGGCAGATACACTTTCTTACTGCTCACATCTTA
CAGGTGAGTACTCATAATTGGCCAGCATCTCACCACCAGCAAGTAGTAGGGCCAGGTCAATCCCAGGCAGTCTGACCCCAGAGTGGCCCA
GCTCATCCCCTACTCTGTTATTTGCTTGTTAATGATTCTCTAGATTTTCTAAAATAATGTTTCTTAGCATTGTGATGATAAAGCTCATGA
TGAACTTTATCACTAGTTATGCCACCTTAACTAGTCAGATTTCCTAGAATTAGGAAATGGTGACTCTTGTCTAAATTTGGTTAAGTGATG
AATTTGGGTTACCGTCTCATGTGAACCTGGAGATTCACCAGTCTTAACTTTTGGGTCATTGTGTTTTCTCTACATTCATGCATTGGATGT
TTTGCTAAATAACTCCTGTGGATTTAGGAATGTGTGCTAATAGCAATCTTCCTAATTTTCATGTTTATATGGAACTATGCAGTTGAGTAT
TGAAAGCTTTAAACTGAGTTTATTTACAAGGACTGAGTCTAGCCTACAGAGAACATACAGCAGCCTTCTTTGGACCACAGTCTTATCCGA
GGGGTCTGTGGTTGTATCAGAAGAGCCACTAAACCAATCCCCCTTTCCAAAATTGAACCTCACAGACGTTCCTGTTTTTTGTGATTGAGA
AACTGGTCAATGAACAGGAAGACTTAGAGATGTTTCACAAGCCTTTGATTTTTGTTTCATTTATTTGTAATAAACCTCTTCCACGTGATG

>21336_21336_1_DAP-CCT5_DAP_chr5_10748287_ENST00000230895_CCT5_chr5_10258223_ENST00000280326_length(amino acids)=415AA_BP=50
MSSPPEGKLETKAGHPPAVKAGGMRIVQKHPHTGDTKEEKDKDDQEWESPRVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVG
GRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGF
DDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIE
EAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMN

--------------------------------------------------------------
>21336_21336_2_DAP-CCT5_DAP_chr5_10748287_ENST00000230895_CCT5_chr5_10258223_ENST00000503026_length(transcript)=1747nt_BP=356nt
GGCTGCGCCACGTCGGCGCGCGGCGGCCGCGCCCCCTTAACGGCAGTGGCACTCACCCGGCTCGCGCGGCCCCGGCGCCCCACGCGCGCG
CGTCGTTCTCCCGCCCGCTCGCTCCCCGGCGCTCACACCTGAGCTCACTCGCGCACGCCCGCCCGGCCCGAGAACCGCGCCGCCGCCTCG
GCCCCGCGGAAGCCCCGCCGCGTCATGTCTTCGCCTCCCGAAGGGAAACTAGAGACTAAAGCTGGACACCCGCCCGCCGTGAAAGCTGGT
GGAATGCGAATTGTGCAGAAACACCCACATACAGGAGACACCAAAGAAGAGAAAGACAAGGATGACCAGGAATGGGAAAGCCCCAGGGTC
AACAGTTGTCACCGACAGATGGCTGAGATTGCTGTGAATGCCGTCCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTT
ATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAGGACACTAAACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAG
ATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATTCTCACATGTCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTG
ACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATACGAAAAGGAGAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAAC
CTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCAAATCACTTACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCT
GAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGGATCGTCCCCAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTT
GTACAGGAGATCTCATTTGGGACAACTAAGGATAAAATGCTGGTCATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGA
GGAGGAAATAAGATGATCATTGAGGAGGCGAAACGATCCCTTCACGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTG
GTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCCCTGGCAGTTAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATG
AGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATGGCCCTCTCTGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGA
GCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGCATCGACTGTTTGCACAAGGGGACAAATGATATGAAGCAACAGCATGTCATAGAA
ACCTTGATTGGCAAAAAGCAACAGATATCTCTTGCAACACAAATGGTTAGAATGATTTTGAAGATTGATGACATTCGTAAGCCTGGAGAA
TCTGAAGAATGAAGACATTGAGAAAACTATGTAGCAAGATCCACTTCTGTGATTAAGTAAATGGATGTCTCGTGATGCATCTACAGTTAT
TTATTGTTACATCCTTTTCCAGACACTGTAGATGCTATAATAAAAATAGCTGTTTGGTAACCATAGTTTCACTTGTTCAAAGCTGTGTAA
TCGTGGGGGTACCATCTCAACTGCTTTTGTATTCATTGTATTAAAAGAATCTGTTTAAACAACCTTTATCTTCTCTTCGGGTTTAAGAAA

>21336_21336_2_DAP-CCT5_DAP_chr5_10748287_ENST00000230895_CCT5_chr5_10258223_ENST00000503026_length(amino acids)=415AA_BP=50
MSSPPEGKLETKAGHPPAVKAGGMRIVQKHPHTGDTKEEKDKDDQEWESPRVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVG
GRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGF
DDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIE
EAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMN

--------------------------------------------------------------
>21336_21336_3_DAP-CCT5_DAP_chr5_10748287_ENST00000230895_CCT5_chr5_10258223_ENST00000506600_length(transcript)=1680nt_BP=356nt
GGCTGCGCCACGTCGGCGCGCGGCGGCCGCGCCCCCTTAACGGCAGTGGCACTCACCCGGCTCGCGCGGCCCCGGCGCCCCACGCGCGCG
CGTCGTTCTCCCGCCCGCTCGCTCCCCGGCGCTCACACCTGAGCTCACTCGCGCACGCCCGCCCGGCCCGAGAACCGCGCCGCCGCCTCG
GCCCCGCGGAAGCCCCGCCGCGTCATGTCTTCGCCTCCCGAAGGGAAACTAGAGACTAAAGCTGGACACCCGCCCGCCGTGAAAGCTGGT
GGAATGCGAATTGTGCAGAAACACCCACATACAGGAGACACCAAAGAAGAGAAAGACAAGGATGACCAGGAATGGGAAAGCCCCAGGGTC
AACAGTTGTCACCGACAGATGGCTGAGATTGCTGTGAATGCCGTCCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTT
ATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAGGACACTAAACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAG
ATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATTCTCACATGTCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTG
ACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATACGAAAAGGAGAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAAC
CTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCAAATCACTTACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCT
GAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGGATCGTCCCCAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTT
GTACAGGAGATCTCATTTGGGACAACTAAGGATAAAATGCTGGTCATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGA
GGAGGAAATAAGATGATCATTGAGGAGGCGAAACGATCCCTTCACGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTG
GTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCCCTGGCAGTTAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATG
AGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATGGCCCTCTCTGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGA
GCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGCATCGACTGTTTGCACAAGGGGACAAATGATATGAAGCAACAGCATGTCATAGAA
ACCTTGATTGGCAAAAAGCAACAGATATCTCTTGCAACACAAATGGTTAGAATGATTTTGAAGATTGATGACATTCGTAAGCCTGGAGAA
TCTGAAGAATGAAGACATTGAGAAAACTATGTAGCAAGATCCACTTCTGTGATTAAGTAAATGGATGTCTCGTGATGCATCTACAGTTAT
TTATTGTTACATCCTTTTCCAGACACTGTAGATGCTATAATAAAAATAGCTGTTTGGTAACCATAGTTTCACTTGTTCAAAGCTGTGTAA

>21336_21336_3_DAP-CCT5_DAP_chr5_10748287_ENST00000230895_CCT5_chr5_10258223_ENST00000506600_length(amino acids)=415AA_BP=50
MSSPPEGKLETKAGHPPAVKAGGMRIVQKHPHTGDTKEEKDKDDQEWESPRVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVG
GRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGF
DDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIE
EAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMN

--------------------------------------------------------------
>21336_21336_4_DAP-CCT5_DAP_chr5_10748287_ENST00000230895_CCT5_chr5_10258223_ENST00000515390_length(transcript)=1594nt_BP=356nt
GGCTGCGCCACGTCGGCGCGCGGCGGCCGCGCCCCCTTAACGGCAGTGGCACTCACCCGGCTCGCGCGGCCCCGGCGCCCCACGCGCGCG
CGTCGTTCTCCCGCCCGCTCGCTCCCCGGCGCTCACACCTGAGCTCACTCGCGCACGCCCGCCCGGCCCGAGAACCGCGCCGCCGCCTCG
GCCCCGCGGAAGCCCCGCCGCGTCATGTCTTCGCCTCCCGAAGGGAAACTAGAGACTAAAGCTGGACACCCGCCCGCCGTGAAAGCTGGT
GGAATGCGAATTGTGCAGAAACACCCACATACAGGAGACACCAAAGAAGAGAAAGACAAGGATGACCAGGAATGGGAAAGCCCCAGGGTC
AACAGTTGTCACCGACAGATGGCTGAGATTGCTGTGAATGCCGTCCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTT
ATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAGGACACTAAACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAG
ATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATTCTCACATGTCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTG
ACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATACGAAAAGGAGAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAAC
CTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCAAATCACTTACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCT
GAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGGATCGTCCCCAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTT
GTACAGGAGATCTCATTTGGGACAACTAAGGATAAAATGCTGGTCATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGA
GGAGGAAATAAGATGATCATTGAGGAGGCGAAACGATCCCTTCACGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTG
GTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCCCTGGCAGTTAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATG
AGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATGGCCCTCTCTGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGA
GCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGCATCGACTGTTTGCACAAGGGGACAAATGATATGAAGCAACAGCATGTCATAGAA
ACCTTGATTGGCAAAAAGCAACAGATATCTCTTGCAACACAAATGGTTAGAATGATTTTGAAGATTGATGACATTCGTAAGCCTGGAGAA
TCTGAAGAATGAAGACATTGAGAAAACTATGTAGCAAGATCCACTTCTGTGATTAAGTAAATGGATGTCTCGTGATGCATCTACAGTTAT

>21336_21336_4_DAP-CCT5_DAP_chr5_10748287_ENST00000230895_CCT5_chr5_10258223_ENST00000515390_length(amino acids)=415AA_BP=50
MSSPPEGKLETKAGHPPAVKAGGMRIVQKHPHTGDTKEEKDKDDQEWESPRVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVG
GRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGF
DDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIE
EAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMN

--------------------------------------------------------------
>21336_21336_5_DAP-CCT5_DAP_chr5_10748287_ENST00000230895_CCT5_chr5_10258223_ENST00000515676_length(transcript)=1571nt_BP=356nt
GGCTGCGCCACGTCGGCGCGCGGCGGCCGCGCCCCCTTAACGGCAGTGGCACTCACCCGGCTCGCGCGGCCCCGGCGCCCCACGCGCGCG
CGTCGTTCTCCCGCCCGCTCGCTCCCCGGCGCTCACACCTGAGCTCACTCGCGCACGCCCGCCCGGCCCGAGAACCGCGCCGCCGCCTCG
GCCCCGCGGAAGCCCCGCCGCGTCATGTCTTCGCCTCCCGAAGGGAAACTAGAGACTAAAGCTGGACACCCGCCCGCCGTGAAAGCTGGT
GGAATGCGAATTGTGCAGAAACACCCACATACAGGAGACACCAAAGAAGAGAAAGACAAGGATGACCAGGAATGGGAAAGCCCCAGGGTC
AACAGTTGTCACCGACAGATGGCTGAGATTGCTGTGAATGCCGTCCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTT
ATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAGGACACTAAACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAG
ATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATTCTCACATGTCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTG
ACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATACGAAAAGGAGAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAAC
CTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCAAATCACTTACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCT
GAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGGATCGTCCCCAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTT
GTACAGGAGATCTCATTTGGGACAACTAAGGATAAAATGCTGGTCATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGA
GGAGGAAATAAGATGATCATTGAGGAGGCGAAACGATCCCTTCACGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTG
GTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCCCTGGCAGTTAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATG
AGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATGGCCCTCTCTGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGA
GCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGCATCGACTGTTTGCACAAGGGGACAAATGATATGAAGCAACAGCATGTCATAGAA
ACCTTGATTGGCAAAAAGCAACAGATATCTCTTGCAACACAAATGGTTAGAATGATTTTGAAGATTGATGACATTCGTAAGCCTGGAGAA
TCTGAAGAATGAAGACATTGAGAAAACTATGTAGCAAGATCCACTTCTGTGATTAAGTAAATGGATGTCTCGTGATGCATCTACAGTTAT

>21336_21336_5_DAP-CCT5_DAP_chr5_10748287_ENST00000230895_CCT5_chr5_10258223_ENST00000515676_length(amino acids)=415AA_BP=50
MSSPPEGKLETKAGHPPAVKAGGMRIVQKHPHTGDTKEEKDKDDQEWESPRVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVG
GRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGF
DDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIE
EAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMN

--------------------------------------------------------------
>21336_21336_6_DAP-CCT5_DAP_chr5_10748287_ENST00000432074_CCT5_chr5_10258223_ENST00000280326_length(transcript)=3037nt_BP=312nt
AGTGGCACTCACCCGGCTCGCGCGGCCCCGGCGCCCCACGCGCGCGCGTCGTTCTCCCGCCCGCTCGCTCCCCGGCGCTCACACCTGAGC
TCACTCGCGCACGCCCGCCCGGCCCGAGAACCGCGCCGCCGCCTCGGCCCCGCGGAAGCCCCGCCGCGTCATGTCTTCGCCTCCCGAAGG
GAAACTAGAGACTAAAGCTGGACACCCGCCCGCCGTGAAAGCTGGTGGAATGCGAATTGTGCAGAAACACCCACATACAGGAGACACCAA
AGAAGAGAAAGACAAGGATGACCAGGAATGGGAAAGCCCCAGGGTCAACAGTTGTCACCGACAGATGGCTGAGATTGCTGTGAATGCCGT
CCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTTATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAGGACACTAA
ACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAGATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATTCTCACATG
TCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTGACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATACGAAAAGGA
GAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAACCTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCAAATCACTT
ACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCTGAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGGATCGTCCC
CAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTTGTACAGGAGATCTCATTTGGGACAACTAAGGATAAAATGCTGGT
CATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGAGGAGGAAATAAGATGATCATTGAGGAGGCGAAACGATCCCTTCA
CGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTGGTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCCCTGGCAGT
TAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATGAGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATGGCCCTCTC
TGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGAGCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGCATCGACTG
TTTGCACAAGGGGACAAATGATATGAAGCAACAGCATGTCATAGAAACCTTGATTGGCAAAAAGCAACAGATATCTCTTGCAACACAAAT
GGTTAGAATGATTTTGAAGATTGATGACATTCGTAAGCCTGGAGAATCTGAAGAATGAAGACATTGAGAAAACTATGTAGCAAGATCCAC
TTCTGTGATTAAGTAAATGGATGTCTCGTGATGCATCTACAGTTATTTATTGTTACATCCTTTTCCAGACACTGTAGATGCTATAATAAA
AATAGCTGTTTGGTAACCATAGTTTCACTTGTTCAAAGCTGTGTAATCGTGGGGGTACCATCTCAACTGCTTTTGTATTCATTGTATTAA
AAGAATCTGTTTAAACAACCTTTATCTTCTCTTCGGGTTTAAGAAACGTTTATTGTAACAGTAATTAAATGCTGCCTTAATTGAAGGGGT
TTGGGTGGATTTTTTTTTCTCAAAATAAGCTGTAGGGACTATTTTAACAGCTTAAACAGGAGCTCTCAAGATGCACTTTCATATTGAGAG
GAATATGGGCTTGATCCTCTTCCTATCTAAATGGGTGGGCCATTTGATTGTAGAGGGTCCACCACAGAATTATGGGATGCCTTAAGTGCT
GTTACTAGGTTGCTCACAGCCTAACCTGGCGTGTTGTTTAGGGCTGATGGAGACCCATGTGAGCCTTTGCTTTCCTCTGGCCCCGGCCCC
ACCCTGAACACAGCTCATACACAGAATCAGGACCAGCATGTGCAGAGCTGGCCACCAGCACAGGCTTAGGGCAGTTCAGAACCCACTTGT
TTCCCTATCAGAGGGACACAGTGAAGTGGAGGTTAAAGTAAATTACAGGAAATAAGGGAGAAATCTTGCAGTTACCATGTTCAGATAGAG
TGACTGAAATTAATTGTACTTACTAAAGTATTAACTAGCTAACAGTGATGGGCCAAGACGCTCCGAGAACTCTACCGGGATTGTCTGTTC
TGACAACCCAGTGAGGCAGATACACTTTCTTACTGCTCACATCTTACAGGTGAGTACTCATAATTGGCCAGCATCTCACCACCAGCAAGT
AGTAGGGCCAGGTCAATCCCAGGCAGTCTGACCCCAGAGTGGCCCAGCTCATCCCCTACTCTGTTATTTGCTTGTTAATGATTCTCTAGA
TTTTCTAAAATAATGTTTCTTAGCATTGTGATGATAAAGCTCATGATGAACTTTATCACTAGTTATGCCACCTTAACTAGTCAGATTTCC
TAGAATTAGGAAATGGTGACTCTTGTCTAAATTTGGTTAAGTGATGAATTTGGGTTACCGTCTCATGTGAACCTGGAGATTCACCAGTCT
TAACTTTTGGGTCATTGTGTTTTCTCTACATTCATGCATTGGATGTTTTGCTAAATAACTCCTGTGGATTTAGGAATGTGTGCTAATAGC
AATCTTCCTAATTTTCATGTTTATATGGAACTATGCAGTTGAGTATTGAAAGCTTTAAACTGAGTTTATTTACAAGGACTGAGTCTAGCC
TACAGAGAACATACAGCAGCCTTCTTTGGACCACAGTCTTATCCGAGGGGTCTGTGGTTGTATCAGAAGAGCCACTAAACCAATCCCCCT
TTCCAAAATTGAACCTCACAGACGTTCCTGTTTTTTGTGATTGAGAAACTGGTCAATGAACAGGAAGACTTAGAGATGTTTCACAAGCCT

>21336_21336_6_DAP-CCT5_DAP_chr5_10748287_ENST00000432074_CCT5_chr5_10258223_ENST00000280326_length(amino acids)=415AA_BP=50
MSSPPEGKLETKAGHPPAVKAGGMRIVQKHPHTGDTKEEKDKDDQEWESPRVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVG
GRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGF
DDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIE
EAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMN

--------------------------------------------------------------
>21336_21336_7_DAP-CCT5_DAP_chr5_10748287_ENST00000432074_CCT5_chr5_10258223_ENST00000503026_length(transcript)=1703nt_BP=312nt
AGTGGCACTCACCCGGCTCGCGCGGCCCCGGCGCCCCACGCGCGCGCGTCGTTCTCCCGCCCGCTCGCTCCCCGGCGCTCACACCTGAGC
TCACTCGCGCACGCCCGCCCGGCCCGAGAACCGCGCCGCCGCCTCGGCCCCGCGGAAGCCCCGCCGCGTCATGTCTTCGCCTCCCGAAGG
GAAACTAGAGACTAAAGCTGGACACCCGCCCGCCGTGAAAGCTGGTGGAATGCGAATTGTGCAGAAACACCCACATACAGGAGACACCAA
AGAAGAGAAAGACAAGGATGACCAGGAATGGGAAAGCCCCAGGGTCAACAGTTGTCACCGACAGATGGCTGAGATTGCTGTGAATGCCGT
CCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTTATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAGGACACTAA
ACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAGATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATTCTCACATG
TCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTGACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATACGAAAAGGA
GAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAACCTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCAAATCACTT
ACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCTGAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGGATCGTCCC
CAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTTGTACAGGAGATCTCATTTGGGACAACTAAGGATAAAATGCTGGT
CATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGAGGAGGAAATAAGATGATCATTGAGGAGGCGAAACGATCCCTTCA
CGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTGGTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCCCTGGCAGT
TAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATGAGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATGGCCCTCTC
TGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGAGCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGCATCGACTG
TTTGCACAAGGGGACAAATGATATGAAGCAACAGCATGTCATAGAAACCTTGATTGGCAAAAAGCAACAGATATCTCTTGCAACACAAAT
GGTTAGAATGATTTTGAAGATTGATGACATTCGTAAGCCTGGAGAATCTGAAGAATGAAGACATTGAGAAAACTATGTAGCAAGATCCAC
TTCTGTGATTAAGTAAATGGATGTCTCGTGATGCATCTACAGTTATTTATTGTTACATCCTTTTCCAGACACTGTAGATGCTATAATAAA
AATAGCTGTTTGGTAACCATAGTTTCACTTGTTCAAAGCTGTGTAATCGTGGGGGTACCATCTCAACTGCTTTTGTATTCATTGTATTAA

>21336_21336_7_DAP-CCT5_DAP_chr5_10748287_ENST00000432074_CCT5_chr5_10258223_ENST00000503026_length(amino acids)=415AA_BP=50
MSSPPEGKLETKAGHPPAVKAGGMRIVQKHPHTGDTKEEKDKDDQEWESPRVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVG
GRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGF
DDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIE
EAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMN

--------------------------------------------------------------
>21336_21336_8_DAP-CCT5_DAP_chr5_10748287_ENST00000432074_CCT5_chr5_10258223_ENST00000506600_length(transcript)=1636nt_BP=312nt
AGTGGCACTCACCCGGCTCGCGCGGCCCCGGCGCCCCACGCGCGCGCGTCGTTCTCCCGCCCGCTCGCTCCCCGGCGCTCACACCTGAGC
TCACTCGCGCACGCCCGCCCGGCCCGAGAACCGCGCCGCCGCCTCGGCCCCGCGGAAGCCCCGCCGCGTCATGTCTTCGCCTCCCGAAGG
GAAACTAGAGACTAAAGCTGGACACCCGCCCGCCGTGAAAGCTGGTGGAATGCGAATTGTGCAGAAACACCCACATACAGGAGACACCAA
AGAAGAGAAAGACAAGGATGACCAGGAATGGGAAAGCCCCAGGGTCAACAGTTGTCACCGACAGATGGCTGAGATTGCTGTGAATGCCGT
CCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTTATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAGGACACTAA
ACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAGATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATTCTCACATG
TCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTGACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATACGAAAAGGA
GAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAACCTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCAAATCACTT
ACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCTGAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGGATCGTCCC
CAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTTGTACAGGAGATCTCATTTGGGACAACTAAGGATAAAATGCTGGT
CATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGAGGAGGAAATAAGATGATCATTGAGGAGGCGAAACGATCCCTTCA
CGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTGGTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCCCTGGCAGT
TAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATGAGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATGGCCCTCTC
TGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGAGCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGCATCGACTG
TTTGCACAAGGGGACAAATGATATGAAGCAACAGCATGTCATAGAAACCTTGATTGGCAAAAAGCAACAGATATCTCTTGCAACACAAAT
GGTTAGAATGATTTTGAAGATTGATGACATTCGTAAGCCTGGAGAATCTGAAGAATGAAGACATTGAGAAAACTATGTAGCAAGATCCAC
TTCTGTGATTAAGTAAATGGATGTCTCGTGATGCATCTACAGTTATTTATTGTTACATCCTTTTCCAGACACTGTAGATGCTATAATAAA
AATAGCTGTTTGGTAACCATAGTTTCACTTGTTCAAAGCTGTGTAATCGTGGGGGTACCATCTCAACTGCTTTTGTATTCATTGTATTAA

>21336_21336_8_DAP-CCT5_DAP_chr5_10748287_ENST00000432074_CCT5_chr5_10258223_ENST00000506600_length(amino acids)=415AA_BP=50
MSSPPEGKLETKAGHPPAVKAGGMRIVQKHPHTGDTKEEKDKDDQEWESPRVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVG
GRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGF
DDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIE
EAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMN

--------------------------------------------------------------
>21336_21336_9_DAP-CCT5_DAP_chr5_10748287_ENST00000432074_CCT5_chr5_10258223_ENST00000515390_length(transcript)=1550nt_BP=312nt
AGTGGCACTCACCCGGCTCGCGCGGCCCCGGCGCCCCACGCGCGCGCGTCGTTCTCCCGCCCGCTCGCTCCCCGGCGCTCACACCTGAGC
TCACTCGCGCACGCCCGCCCGGCCCGAGAACCGCGCCGCCGCCTCGGCCCCGCGGAAGCCCCGCCGCGTCATGTCTTCGCCTCCCGAAGG
GAAACTAGAGACTAAAGCTGGACACCCGCCCGCCGTGAAAGCTGGTGGAATGCGAATTGTGCAGAAACACCCACATACAGGAGACACCAA
AGAAGAGAAAGACAAGGATGACCAGGAATGGGAAAGCCCCAGGGTCAACAGTTGTCACCGACAGATGGCTGAGATTGCTGTGAATGCCGT
CCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTTATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAGGACACTAA
ACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAGATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATTCTCACATG
TCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTGACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATACGAAAAGGA
GAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAACCTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCAAATCACTT
ACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCTGAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGGATCGTCCC
CAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTTGTACAGGAGATCTCATTTGGGACAACTAAGGATAAAATGCTGGT
CATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGAGGAGGAAATAAGATGATCATTGAGGAGGCGAAACGATCCCTTCA
CGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTGGTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCCCTGGCAGT
TAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATGAGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATGGCCCTCTC
TGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGAGCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGCATCGACTG
TTTGCACAAGGGGACAAATGATATGAAGCAACAGCATGTCATAGAAACCTTGATTGGCAAAAAGCAACAGATATCTCTTGCAACACAAAT
GGTTAGAATGATTTTGAAGATTGATGACATTCGTAAGCCTGGAGAATCTGAAGAATGAAGACATTGAGAAAACTATGTAGCAAGATCCAC
TTCTGTGATTAAGTAAATGGATGTCTCGTGATGCATCTACAGTTATTTATTGTTACATCCTTTTCCAGACACTGTAGATGCTATAATAAA

>21336_21336_9_DAP-CCT5_DAP_chr5_10748287_ENST00000432074_CCT5_chr5_10258223_ENST00000515390_length(amino acids)=415AA_BP=50
MSSPPEGKLETKAGHPPAVKAGGMRIVQKHPHTGDTKEEKDKDDQEWESPRVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVG
GRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGF
DDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIE
EAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMN

--------------------------------------------------------------
>21336_21336_10_DAP-CCT5_DAP_chr5_10748287_ENST00000432074_CCT5_chr5_10258223_ENST00000515676_length(transcript)=1527nt_BP=312nt
AGTGGCACTCACCCGGCTCGCGCGGCCCCGGCGCCCCACGCGCGCGCGTCGTTCTCCCGCCCGCTCGCTCCCCGGCGCTCACACCTGAGC
TCACTCGCGCACGCCCGCCCGGCCCGAGAACCGCGCCGCCGCCTCGGCCCCGCGGAAGCCCCGCCGCGTCATGTCTTCGCCTCCCGAAGG
GAAACTAGAGACTAAAGCTGGACACCCGCCCGCCGTGAAAGCTGGTGGAATGCGAATTGTGCAGAAACACCCACATACAGGAGACACCAA
AGAAGAGAAAGACAAGGATGACCAGGAATGGGAAAGCCCCAGGGTCAACAGTTGTCACCGACAGATGGCTGAGATTGCTGTGAATGCCGT
CCTCACTGTAGCAGATATGGAGCGGAGAGACGTTGACTTTGAGCTTATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAGGACACTAA
ACTGATTAAGGGCGTGATTGTGGACAAGGATTTCAGTCACCCACAGATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATTCTCACATG
TCCATTTGAACCACCCAAACCAAAAACAAAGCATAAGCTGGATGTGACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATACGAAAAGGA
GAAATTTGAAGAGATGATTCAACAAATTAAAGAGACTGGTGCTAACCTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCAAATCACTT
ACTTCTTCAGAACAACTTGCCTGCGGTTCGCTGGGTAGGAGGACCTGAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGGATCGTCCC
CAGGTTCTCAGAGCTCACAGCCGAGAAGCTGGGCTTTGCTGGTCTTGTACAGGAGATCTCATTTGGGACAACTAAGGATAAAATGCTGGT
CATCGAGCAGTGTAAGAACTCCAGAGCTGTAACCATTTTTATTAGAGGAGGAAATAAGATGATCATTGAGGAGGCGAAACGATCCCTTCA
CGATGCTTTGTGTGTCATCCGGAACCTCATCCGCGATAATCGTGTGGTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCCCTGGCAGT
TAGCCAAGAGGCGGATAAGTGCCCCACCTTAGAACAGTATGCCATGAGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATGGCCCTCTC
TGAAAACAGTGGCATGAATCCCATCCAGACTATGACCGAAGTCCGAGCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGCATCGACTG
TTTGCACAAGGGGACAAATGATATGAAGCAACAGCATGTCATAGAAACCTTGATTGGCAAAAAGCAACAGATATCTCTTGCAACACAAAT
GGTTAGAATGATTTTGAAGATTGATGACATTCGTAAGCCTGGAGAATCTGAAGAATGAAGACATTGAGAAAACTATGTAGCAAGATCCAC

>21336_21336_10_DAP-CCT5_DAP_chr5_10748287_ENST00000432074_CCT5_chr5_10258223_ENST00000515676_length(amino acids)=415AA_BP=50
MSSPPEGKLETKAGHPPAVKAGGMRIVQKHPHTGDTKEEKDKDDQEWESPRVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVG
GRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGF
DDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIE
EAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMN

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Fusion Gene PPI Analysis for DAP-CCT5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DAP-CCT5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DAP-CCT5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource