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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DBN1-ZNF346 (FusionGDB2 ID:21447)

Fusion Gene Summary for DBN1-ZNF346

check button Fusion gene summary
Fusion gene informationFusion gene name: DBN1-ZNF346
Fusion gene ID: 21447
HgeneTgene
Gene symbol

DBN1

ZNF346

Gene ID

1627

23567

Gene namedrebrin 1zinc finger protein 346
SynonymsD0S117EJAZ|Zfp346
Cytomap

5q35.3

5q35.2

Type of geneprotein-codingprotein-coding
Descriptiondrebrindevelopmentally-regulated brain proteindrebrin Adrebrin Edrebrin E2zinc finger protein 346double-stranded RNA-binding zinc finger protein JAZjust another zinc finger protein
Modification date2020032020200313
UniProtAcc

Q16643

.
Ensembl transtripts involved in fusion geneENST00000292385, ENST00000309007, 
ENST00000393565, ENST00000393563, 
ENST00000512501, 		ENST00000261948, 
ENST00000503039, ENST00000503425, 
ENST00000511834, ENST00000512315, 
ENST00000358149, ENST00000506693, 
Fusion gene scores* DoF score4 X 5 X 2=404 X 12 X 8=384
# samples 518
** MAII scorelog2(5/40*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(18/384*10)=-1.09310940439148
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DBN1 [Title/Abstract] AND ZNF346 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDBN1(176893773)-ZNF346(176491513), # samples:1
DBN1(176890102)-ZNF346(176458162), # samples:1
Anticipated loss of major functional domain due to fusion event.DBN1-ZNF346 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
DBN1-ZNF346 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneDBN1

GO:0051220

cytoplasmic sequestering of protein

28966017


check buttonFusion gene breakpoints across DBN1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ZNF346 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4THCATCGA-EM-A2P1-01ADBN1chr5

176893773

-ZNF346chr5

176491513

+
ChiTaRS5.0N/AEI707918DBN1chr5

176890102

-ZNF346chr5

176458162

-


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Fusion Gene ORF analysis for DBN1-ZNF346

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000292385ENST00000261948DBN1chr5

176893773

-ZNF346chr5

176491513

+
Frame-shiftENST00000292385ENST00000503039DBN1chr5

176893773

-ZNF346chr5

176491513

+
Frame-shiftENST00000292385ENST00000503425DBN1chr5

176893773

-ZNF346chr5

176491513

+
Frame-shiftENST00000292385ENST00000511834DBN1chr5

176893773

-ZNF346chr5

176491513

+
Frame-shiftENST00000292385ENST00000512315DBN1chr5

176893773

-ZNF346chr5

176491513

+
Frame-shiftENST00000309007ENST00000261948DBN1chr5

176893773

-ZNF346chr5

176491513

+
Frame-shiftENST00000309007ENST00000503039DBN1chr5

176893773

-ZNF346chr5

176491513

+
Frame-shiftENST00000309007ENST00000503425DBN1chr5

176893773

-ZNF346chr5

176491513

+
Frame-shiftENST00000309007ENST00000511834DBN1chr5

176893773

-ZNF346chr5

176491513

+
Frame-shiftENST00000309007ENST00000512315DBN1chr5

176893773

-ZNF346chr5

176491513

+
Frame-shiftENST00000393565ENST00000261948DBN1chr5

176893773

-ZNF346chr5

176491513

+
Frame-shiftENST00000393565ENST00000503039DBN1chr5

176893773

-ZNF346chr5

176491513

+
Frame-shiftENST00000393565ENST00000503425DBN1chr5

176893773

-ZNF346chr5

176491513

+
Frame-shiftENST00000393565ENST00000511834DBN1chr5

176893773

-ZNF346chr5

176491513

+
Frame-shiftENST00000393565ENST00000512315DBN1chr5

176893773

-ZNF346chr5

176491513

+
In-frameENST00000292385ENST00000358149DBN1chr5

176893773

-ZNF346chr5

176491513

+
In-frameENST00000292385ENST00000506693DBN1chr5

176893773

-ZNF346chr5

176491513

+
In-frameENST00000309007ENST00000358149DBN1chr5

176893773

-ZNF346chr5

176491513

+
In-frameENST00000309007ENST00000506693DBN1chr5

176893773

-ZNF346chr5

176491513

+
In-frameENST00000393565ENST00000358149DBN1chr5

176893773

-ZNF346chr5

176491513

+
In-frameENST00000393565ENST00000506693DBN1chr5

176893773

-ZNF346chr5

176491513

+
intron-3CDSENST00000393563ENST00000261948DBN1chr5

176893773

-ZNF346chr5

176491513

+
intron-3CDSENST00000393563ENST00000358149DBN1chr5

176893773

-ZNF346chr5

176491513

+
intron-3CDSENST00000393563ENST00000503039DBN1chr5

176893773

-ZNF346chr5

176491513

+
intron-3CDSENST00000393563ENST00000503425DBN1chr5

176893773

-ZNF346chr5

176491513

+
intron-3CDSENST00000393563ENST00000506693DBN1chr5

176893773

-ZNF346chr5

176491513

+
intron-3CDSENST00000393563ENST00000511834DBN1chr5

176893773

-ZNF346chr5

176491513

+
intron-3CDSENST00000393563ENST00000512315DBN1chr5

176893773

-ZNF346chr5

176491513

+
intron-3CDSENST00000512501ENST00000261948DBN1chr5

176893773

-ZNF346chr5

176491513

+
intron-3CDSENST00000512501ENST00000358149DBN1chr5

176893773

-ZNF346chr5

176491513

+
intron-3CDSENST00000512501ENST00000503039DBN1chr5

176893773

-ZNF346chr5

176491513

+
intron-3CDSENST00000512501ENST00000503425DBN1chr5

176893773

-ZNF346chr5

176491513

+
intron-3CDSENST00000512501ENST00000506693DBN1chr5

176893773

-ZNF346chr5

176491513

+
intron-3CDSENST00000512501ENST00000511834DBN1chr5

176893773

-ZNF346chr5

176491513

+
intron-3CDSENST00000512501ENST00000512315DBN1chr5

176893773

-ZNF346chr5

176491513

+
intron-intronENST00000292385ENST00000261948DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000292385ENST00000358149DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000292385ENST00000503039DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000292385ENST00000503425DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000292385ENST00000506693DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000292385ENST00000511834DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000292385ENST00000512315DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000309007ENST00000261948DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000309007ENST00000358149DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000309007ENST00000503039DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000309007ENST00000503425DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000309007ENST00000506693DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000309007ENST00000511834DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000309007ENST00000512315DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000393563ENST00000261948DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000393563ENST00000358149DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000393563ENST00000503039DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000393563ENST00000503425DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000393563ENST00000506693DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000393563ENST00000511834DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000393563ENST00000512315DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000393565ENST00000261948DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000393565ENST00000358149DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000393565ENST00000503039DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000393565ENST00000503425DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000393565ENST00000506693DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000393565ENST00000511834DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000393565ENST00000512315DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000512501ENST00000261948DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000512501ENST00000358149DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000512501ENST00000503039DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000512501ENST00000503425DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000512501ENST00000506693DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000512501ENST00000511834DBN1chr5

176890102

-ZNF346chr5

176458162

-
intron-intronENST00000512501ENST00000512315DBN1chr5

176890102

-ZNF346chr5

176458162

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000309007DBN1chr5176893773-ENST00000506693ZNF346chr5176491513+1721991911236381
ENST00000309007DBN1chr5176893773-ENST00000358149ZNF346chr5176491513+2465991911236381
ENST00000292385DBN1chr5176893773-ENST00000506693ZNF346chr5176491513+211713874361632398
ENST00000292385DBN1chr5176893773-ENST00000358149ZNF346chr5176491513+286113874361632398
ENST00000393565DBN1chr5176893773-ENST00000506693ZNF346chr5176491513+1617887861132348
ENST00000393565DBN1chr5176893773-ENST00000358149ZNF346chr5176491513+2361887861132348

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000309007ENST00000506693DBN1chr5176893773-ZNF346chr5176491513+0.0038248250.99617517
ENST00000309007ENST00000358149DBN1chr5176893773-ZNF346chr5176491513+0.0052568460.9947431
ENST00000292385ENST00000506693DBN1chr5176893773-ZNF346chr5176491513+0.0045511940.99544877
ENST00000292385ENST00000358149DBN1chr5176893773-ZNF346chr5176491513+0.0030110370.99698895
ENST00000393565ENST00000506693DBN1chr5176893773-ZNF346chr5176491513+0.0037833860.9962166
ENST00000393565ENST00000358149DBN1chr5176893773-ZNF346chr5176491513+0.0043786990.99562126

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Fusion Genomic Features for DBN1-ZNF346


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DBN1chr5176893772-ZNF346chr5176491512+0.0003678190.9996321
DBN1chr5176893772-ZNF346chr5176491512+0.0003678190.9996321

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for DBN1-ZNF346


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr5:176893773/chr5:176491513)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DBN1

Q16643

.
FUNCTION: Actin cytoskeleton-organizing protein that plays a role in the formation of cell projections (PubMed:20215400). Required for actin polymerization at immunological synapses (IS) and for the recruitment of the chemokine receptor CXCR4 to IS (PubMed:20215400). Plays a role in dendritic spine morphogenesis and organization, including the localization of the dopamine receptor DRD1 to the dendritic spines (By similarity). Involved in memory-related synaptic plasticity in the hippocampus (By similarity). {ECO:0000250|UniProtKB:Q9QXS6, ECO:0000269|PubMed:20215400}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDBN1chr5:176893773chr5:176491513ENST00000292385-9153_134259652.0DomainADF-H
HgeneDBN1chr5:176893773chr5:176491513ENST00000309007-8143_134257650.0DomainADF-H
HgeneDBN1chr5:176893773chr5:176491513ENST00000393565-8153_134257696.0DomainADF-H

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneZNF346chr5:176893773chr5:176491513ENST0000026194868131_165290320.0Zinc fingerNote=Matrin-type 2
TgeneZNF346chr5:176893773chr5:176491513ENST0000026194868182_216290320.0Zinc fingerNote=Matrin-type 3
TgeneZNF346chr5:176893773chr5:176491513ENST0000026194868236_270290320.0Zinc fingerNote=Matrin-type 4
TgeneZNF346chr5:176893773chr5:176491513ENST000002619486870_104290320.0Zinc fingerNote=Matrin-type 1
TgeneZNF346chr5:176893773chr5:176491513ENST0000035814957131_165265295.0Zinc fingerNote=Matrin-type 2
TgeneZNF346chr5:176893773chr5:176491513ENST0000035814957182_216265295.0Zinc fingerNote=Matrin-type 3
TgeneZNF346chr5:176893773chr5:176491513ENST0000035814957236_270265295.0Zinc fingerNote=Matrin-type 4
TgeneZNF346chr5:176893773chr5:176491513ENST000003581495770_104265295.0Zinc fingerNote=Matrin-type 1
TgeneZNF346chr5:176893773chr5:176491513ENST0000050303969131_165290863.0Zinc fingerNote=Matrin-type 2
TgeneZNF346chr5:176893773chr5:176491513ENST0000050303969182_216290863.0Zinc fingerNote=Matrin-type 3
TgeneZNF346chr5:176893773chr5:176491513ENST0000050303969236_270290863.0Zinc fingerNote=Matrin-type 4
TgeneZNF346chr5:176893773chr5:176491513ENST000005030396970_104290863.0Zinc fingerNote=Matrin-type 1


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Fusion Gene Sequence for DBN1-ZNF346


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>21447_21447_1_DBN1-ZNF346_DBN1_chr5_176893773_ENST00000292385_ZNF346_chr5_176491513_ENST00000358149_length(transcript)=2861nt_BP=1387nt
GGCGGCCGGACGCGGCCCGGAGGCGCGGGGTCCCGATGTGGGGCCCGGGGCCGCGTGGCCCTGCGGGAGCCCATCCCCCACCCTACCCCC
CGGGCCCGGGGGACAGGTGTGCACGGGGCGGCCAAGGGCACCTTCGCCACCTTCGAGCGGGCGAGGTCCGGGCGGGGACGGGGCGGGGAC
CGAGCTAGCGGAGCCAGCGCAGCCTGCCCGGCTCAGCCCGGCCCGGCCACAGCACAAAGGAAAGCGAGGGCGGGGGAGGAGCGGAGCGGG
CTGGGGGCCGGGCGCCCCGCCCACCGGGGGGCCTCTCGGAGTGGGCCGCCCTCCCCCCGAAACCTGGGCTGGAGTGAGGTGGAAGGATGT
TTGCTGCCACATGGCGACCGCGAAGTGACTCCCTTACCGCCGCGGGTCGCGGAGGAGGCAGGGGGAAGGTGCCCATCTGGTTCCTAGGCC
TCCTCTCCCTGCTGGCAGATGGGAACAGGTTCTTCTTGAGGAAACTGAGGCAAAGAGGAGGGCAGGTCTGAGGGACCCCGCTTGGGCTGG
CCTCACCCGCACACTGGGAGGGCAGCCAGGTGGGGACTCTGACCTGGGGGCTTCTGGAGGAGAGGATGAGATGGCTGGGCATCCATGGCA
TGGTACTGCAGCACTGGCCAGCAGCCAGGCCTGGAGGGATGGACGCGAGAGACAAGCTCTCGTGTCCTGCAGGGCTCTGTACACATATGA
AGATGGCTCCGATGACCTCAAGCTTGCAGCATCAGGAGAAGGGGGCTTGCAGGAGCTTTCGGGACACTTTGAGAACCAGAAGGTGATGTA
CGGCTTCTGCAGTGTCAAGGACTCCCAAGCTGCTCTGCCAAAATACGTGCTCATCAACTGGGTGGGCGAAGATGTGCCTGATGCCCGCAA
GTGCGCTTGTGCCAGCCACGTGGCTAAGGTGGCGGAGTTCTTCCAGGGTGTCGACGTGATCGTGAACGCCAGCAGCGTGGAAGACATAGA
CGCGGGTGCCATCGGGCAGCGGCTCTCTAACGGGCTGGCGCGACTCTCCAGCCCTGTGCTGCACCGACTGCGGCTGCGAGAGGATGAGAA
CGCAGAGCCCGTGGGCACCACCTACCAGAAGACGGATGCAGCTGTGGAAATGAAGCGGATTAACCGAGAGCAGTTCTGGGAGCAGGCCAA
GAAGGAAGAAGAGCTGCGGAAGGAGGAGGAGCGGAAGAAGGCCCTGGATGAGAGGCTCAGGTTCGAGCAGGAGCGGATGGAGCAGGAGCG
GCAGGAGCAAGAGGAGCGCGAGCGGCGCTACCGGGAGCGGGAGCAGCAGATCGAGGAGCACAGGAGGAAACAGCAGACTTTAGAAGCGGA
AGAGGCCAAGAGGCGGTTGAAGGAGCAGTCTATCTTTGTCACCAAAAACAGTGGCATCATCCCTGGGCCAGATTCCAATGCAAAGGCAAC
CCATTCAGAAAGACTCAACCACCTTGGAAGACTAGAGGTGATTCTGCCCAGCATCCCATATTGGGCCAGCCATGAGCCAGCTTCCCGTGA
CTGCTCAGCCCTTGGCTCCCTCTTGCTCGTTGTTCTCACCAGGAAAGTACACGGGCCTGAGGCAGGATTGGGCCACAGACAGCCTCTCAT
TGGTCCGGGCTAATTCACTCCTGCTGCTCCCCTTTGGCAGGGGTCCTGTAGGTCATGACAGGGGAGGCAAGGGTATTGAGAGACTCGGGG
TCTCGCGGGGTGGTAGTTTGGAGGGTGGCTTTCCCCATTTCCCAACCCCTCTGGGCCTTAGGTGCTGAGGCCCCTGCCACCTGTCTTTCC
TCTAAAGGTCAGTTTTGGGCCAGTTCTTGCAACTAAAGAGCAGAGATCTCTCTGGGCCCTAGACATTTCCAGCAAAACCTGGAACTTTCA
TGCCAAACCTGGGGCAGGGCAGGAAACAGAGGAAATGGCTGCAACATGGGAGCTTGGAGCTAATACGACACTCTGCCTTCCCCCAGAAGG
TGCAGGCTTTCCTGAGTCTTAGACCAGATATGGCCAGTTGCGCAGGTTTCTGCCAACTGTGAAGTATCCTCCTGGAGCAGTGACACAATC
TTGGCGGAGCATTGCTACCCCCGCTGCCCCCTCCACAGTTCCTGAATGGTGCTAAGGATCTGCAGCAGTTGGCAACGAGCTGGGGCTGGG
GGCGGCCTCCATGTCCACTGAGATCATAGGACACTCCAATGGGGATGGGACCTTTCCCCTCCTCCATCAGAGGTGCTCTGACCCTAGGTT
ACACGGGAAAGTGCCCCACATGCAAGTCTCCCTGAGGGTTCTGCCCCTAAAGGCAGACTGCCTCATGCCCGCTAGCTGTGAGGTTCATTG
CTACCCTCGGCCCTACTAGCCCTCTCTTCCCCCTTGTGCAGCGGACCACTTGCCCAGTTTGCTGTGGTGCTAGCCTTCCCCATCATCCAC
CGGGTGATTTCTGGGTCCCAGGGAAAGAAAGAGAGAGCTGATGCAGGTTTCTACAGTGAGGAACAGGCGTTTCCCAGGCCCCACACCCAG
ATTTCTCTATCTTTGCTGTGTTTTATGGCCTGGGACTGAGTCCACACGGATAGATTTTTCCTTGTAACCTTGAGACGAGAATTCCAAGGA
GTGTCACCATCAGAGGCTTCTCTTCATTGTGTCAAAGAAGCCCCTAGCTGCTCTCGTGGCCTCCTTCCCCCACTCCCTATCCCTTCACCT
GTGAAATGCCTTTGCTTTGCATATTGTGTGTGGATGTGTGTGTGTGTGTGTGTGTGTTTGTGTGTATGTGTGTGCTTCTGTGTGTGCCTA

>21447_21447_1_DBN1-ZNF346_DBN1_chr5_176893773_ENST00000292385_ZNF346_chr5_176491513_ENST00000358149_length(amino acids)=398AA_BP=315
MVPRPPLPAGRWEQVLLEETEAKRRAGLRDPAWAGLTRTLGGQPGGDSDLGASGGEDEMAGHPWHGTAALASSQAWRDGRERQALVSCRA
LYTYEDGSDDLKLAASGEGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASS
VEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQER
MEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFVTKNSGIIPGPDSNAKATHSERLNHLGRLEVILPSIPYWASHE

--------------------------------------------------------------
>21447_21447_2_DBN1-ZNF346_DBN1_chr5_176893773_ENST00000292385_ZNF346_chr5_176491513_ENST00000506693_length(transcript)=2117nt_BP=1387nt
GGCGGCCGGACGCGGCCCGGAGGCGCGGGGTCCCGATGTGGGGCCCGGGGCCGCGTGGCCCTGCGGGAGCCCATCCCCCACCCTACCCCC
CGGGCCCGGGGGACAGGTGTGCACGGGGCGGCCAAGGGCACCTTCGCCACCTTCGAGCGGGCGAGGTCCGGGCGGGGACGGGGCGGGGAC
CGAGCTAGCGGAGCCAGCGCAGCCTGCCCGGCTCAGCCCGGCCCGGCCACAGCACAAAGGAAAGCGAGGGCGGGGGAGGAGCGGAGCGGG
CTGGGGGCCGGGCGCCCCGCCCACCGGGGGGCCTCTCGGAGTGGGCCGCCCTCCCCCCGAAACCTGGGCTGGAGTGAGGTGGAAGGATGT
TTGCTGCCACATGGCGACCGCGAAGTGACTCCCTTACCGCCGCGGGTCGCGGAGGAGGCAGGGGGAAGGTGCCCATCTGGTTCCTAGGCC
TCCTCTCCCTGCTGGCAGATGGGAACAGGTTCTTCTTGAGGAAACTGAGGCAAAGAGGAGGGCAGGTCTGAGGGACCCCGCTTGGGCTGG
CCTCACCCGCACACTGGGAGGGCAGCCAGGTGGGGACTCTGACCTGGGGGCTTCTGGAGGAGAGGATGAGATGGCTGGGCATCCATGGCA
TGGTACTGCAGCACTGGCCAGCAGCCAGGCCTGGAGGGATGGACGCGAGAGACAAGCTCTCGTGTCCTGCAGGGCTCTGTACACATATGA
AGATGGCTCCGATGACCTCAAGCTTGCAGCATCAGGAGAAGGGGGCTTGCAGGAGCTTTCGGGACACTTTGAGAACCAGAAGGTGATGTA
CGGCTTCTGCAGTGTCAAGGACTCCCAAGCTGCTCTGCCAAAATACGTGCTCATCAACTGGGTGGGCGAAGATGTGCCTGATGCCCGCAA
GTGCGCTTGTGCCAGCCACGTGGCTAAGGTGGCGGAGTTCTTCCAGGGTGTCGACGTGATCGTGAACGCCAGCAGCGTGGAAGACATAGA
CGCGGGTGCCATCGGGCAGCGGCTCTCTAACGGGCTGGCGCGACTCTCCAGCCCTGTGCTGCACCGACTGCGGCTGCGAGAGGATGAGAA
CGCAGAGCCCGTGGGCACCACCTACCAGAAGACGGATGCAGCTGTGGAAATGAAGCGGATTAACCGAGAGCAGTTCTGGGAGCAGGCCAA
GAAGGAAGAAGAGCTGCGGAAGGAGGAGGAGCGGAAGAAGGCCCTGGATGAGAGGCTCAGGTTCGAGCAGGAGCGGATGGAGCAGGAGCG
GCAGGAGCAAGAGGAGCGCGAGCGGCGCTACCGGGAGCGGGAGCAGCAGATCGAGGAGCACAGGAGGAAACAGCAGACTTTAGAAGCGGA
AGAGGCCAAGAGGCGGTTGAAGGAGCAGTCTATCTTTGTCACCAAAAACAGTGGCATCATCCCTGGGCCAGATTCCAATGCAAAGGCAAC
CCATTCAGAAAGACTCAACCACCTTGGAAGACTAGAGGTGATTCTGCCCAGCATCCCATATTGGGCCAGCCATGAGCCAGCTTCCCGTGA
CTGCTCAGCCCTTGGCTCCCTCTTGCTCGTTGTTCTCACCAGGAAAGTACACGGGCCTGAGGCAGGATTGGGCCACAGACAGCCTCTCAT
TGGTCCGGGCTAATTCACTCCTGCTGCTCCCCTTTGGCAGGGGTCCTGTAGGTCATGACAGGGGAGGCAAGGGTATTGAGAGACTCGGGG
TCTCGCGGGGTGGTAGTTTGGAGGGTGGCTTTCCCCATTTCCCAACCCCTCTGGGCCTTAGGTGCTGAGGCCCCTGCCACCTGTCTTTCC
TCTAAAGGTCAGTTTTGGGCCAGTTCTTGCAACTAAAGAGCAGAGATCTCTCTGGGCCCTAGACATTTCCAGCAAAACCTGGAACTTTCA
TGCCAAACCTGGGGCAGGGCAGGAAACAGAGGAAATGGCTGCAACATGGGAGCTTGGAGCTAATACGACACTCTGCCTTCCCCCAGAAGG
TGCAGGCTTTCCTGAGTCTTAGACCAGATATGGCCAGTTGCGCAGGTTTCTGCCAACTGTGAAGTATCCTCCTGGAGCAGTGACACAATC

>21447_21447_2_DBN1-ZNF346_DBN1_chr5_176893773_ENST00000292385_ZNF346_chr5_176491513_ENST00000506693_length(amino acids)=398AA_BP=315
MVPRPPLPAGRWEQVLLEETEAKRRAGLRDPAWAGLTRTLGGQPGGDSDLGASGGEDEMAGHPWHGTAALASSQAWRDGRERQALVSCRA
LYTYEDGSDDLKLAASGEGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASS
VEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQER
MEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFVTKNSGIIPGPDSNAKATHSERLNHLGRLEVILPSIPYWASHE

--------------------------------------------------------------
>21447_21447_3_DBN1-ZNF346_DBN1_chr5_176893773_ENST00000309007_ZNF346_chr5_176491513_ENST00000358149_length(transcript)=2465nt_BP=991nt
GGGCGGCGCTAGGACCGAGCGAGCGGAGGGAGCGAGCCGGGCGGAGCCAGCGCCCCCCGCCCCCCGCCGGCCGGCTCCCCTCCCCCGGCC
GCTGGCTCGCTCGGCTCGCGACGCTGCAGAGGCTCCGAGGCGGCGGCGGCGACTCCCTCTTTCCCTCCCTCCTCCTCCGTCCGCCCGTCC
GTCCGCGCGTCTGTCCGTTCGGCCCGGTCCGGCCCGAAGCATGGCCGGCGTCAGCTTCAGCGGCCACCGCCTGGAGCTGCTGGCGGCTTA
CGAGGAGGTGATCCGAGAGGAGAGCGCGGCCGACTGGGCTCTGTACACATATGAAGATGGCTCCGATGACCTCAAGCTTGCAGCATCAGG
AGAAGGGGGCTTGCAGGAGCTTTCGGGACACTTTGAGAACCAGAAGGTGATGTACGGCTTCTGCAGTGTCAAGGACTCCCAAGCTGCTCT
GCCAAAATACGTGCTCATCAACTGGGTGGGCGAAGATGTGCCTGATGCCCGCAAGTGCGCTTGTGCCAGCCACGTGGCTAAGGTGGCGGA
GTTCTTCCAGGGTGTCGACGTGATCGTGAACGCCAGCAGCGTGGAAGACATAGACGCGGGTGCCATCGGGCAGCGGCTCTCTAACGGGCT
GGCGCGACTCTCCAGCCCTGTGCTGCACCGACTGCGGCTGCGAGAGGATGAGAACGCAGAGCCCGTGGGCACCACCTACCAGAAGACGGA
TGCAGCTGTGGAAATGAAGCGGATTAACCGAGAGCAGTTCTGGGAGCAGGCCAAGAAGGAAGAAGAGCTGCGGAAGGAGGAGGAGCGGAA
GAAGGCCCTGGATGAGAGGCTCAGGTTCGAGCAGGAGCGGATGGAGCAGGAGCGGCAGGAGCAAGAGGAGCGCGAGCGGCGCTACCGGGA
GCGGGAGCAGCAGATCGAGGAGCACAGGAGGAAACAGCAGACTTTAGAAGCGGAAGAGGCCAAGAGGCGGTTGAAGGAGCAGTCTATCTT
TGTCACCAAAAACAGTGGCATCATCCCTGGGCCAGATTCCAATGCAAAGGCAACCCATTCAGAAAGACTCAACCACCTTGGAAGACTAGA
GGTGATTCTGCCCAGCATCCCATATTGGGCCAGCCATGAGCCAGCTTCCCGTGACTGCTCAGCCCTTGGCTCCCTCTTGCTCGTTGTTCT
CACCAGGAAAGTACACGGGCCTGAGGCAGGATTGGGCCACAGACAGCCTCTCATTGGTCCGGGCTAATTCACTCCTGCTGCTCCCCTTTG
GCAGGGGTCCTGTAGGTCATGACAGGGGAGGCAAGGGTATTGAGAGACTCGGGGTCTCGCGGGGTGGTAGTTTGGAGGGTGGCTTTCCCC
ATTTCCCAACCCCTCTGGGCCTTAGGTGCTGAGGCCCCTGCCACCTGTCTTTCCTCTAAAGGTCAGTTTTGGGCCAGTTCTTGCAACTAA
AGAGCAGAGATCTCTCTGGGCCCTAGACATTTCCAGCAAAACCTGGAACTTTCATGCCAAACCTGGGGCAGGGCAGGAAACAGAGGAAAT
GGCTGCAACATGGGAGCTTGGAGCTAATACGACACTCTGCCTTCCCCCAGAAGGTGCAGGCTTTCCTGAGTCTTAGACCAGATATGGCCA
GTTGCGCAGGTTTCTGCCAACTGTGAAGTATCCTCCTGGAGCAGTGACACAATCTTGGCGGAGCATTGCTACCCCCGCTGCCCCCTCCAC
AGTTCCTGAATGGTGCTAAGGATCTGCAGCAGTTGGCAACGAGCTGGGGCTGGGGGCGGCCTCCATGTCCACTGAGATCATAGGACACTC
CAATGGGGATGGGACCTTTCCCCTCCTCCATCAGAGGTGCTCTGACCCTAGGTTACACGGGAAAGTGCCCCACATGCAAGTCTCCCTGAG
GGTTCTGCCCCTAAAGGCAGACTGCCTCATGCCCGCTAGCTGTGAGGTTCATTGCTACCCTCGGCCCTACTAGCCCTCTCTTCCCCCTTG
TGCAGCGGACCACTTGCCCAGTTTGCTGTGGTGCTAGCCTTCCCCATCATCCACCGGGTGATTTCTGGGTCCCAGGGAAAGAAAGAGAGA
GCTGATGCAGGTTTCTACAGTGAGGAACAGGCGTTTCCCAGGCCCCACACCCAGATTTCTCTATCTTTGCTGTGTTTTATGGCCTGGGAC
TGAGTCCACACGGATAGATTTTTCCTTGTAACCTTGAGACGAGAATTCCAAGGAGTGTCACCATCAGAGGCTTCTCTTCATTGTGTCAAA
GAAGCCCCTAGCTGCTCTCGTGGCCTCCTTCCCCCACTCCCTATCCCTTCACCTGTGAAATGCCTTTGCTTTGCATATTGTGTGTGGATG
TGTGTGTGTGTGTGTGTGTGTTTGTGTGTATGTGTGTGCTTCTGTGTGTGCCTAATGCTCTGTCTCTTGGTCACTGAAGCATCCAAATAA

>21447_21447_3_DBN1-ZNF346_DBN1_chr5_176893773_ENST00000309007_ZNF346_chr5_176491513_ENST00000358149_length(amino acids)=381AA_BP=298
MARSARDAAEAPRRRRRLPLSLPPPPSARPSARLSVRPGPARSMAGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASG
EGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGL
ARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYRE
REQQIEEHRRKQQTLEAEEAKRRLKEQSIFVTKNSGIIPGPDSNAKATHSERLNHLGRLEVILPSIPYWASHEPASRDCSALGSLLLVVL

--------------------------------------------------------------
>21447_21447_4_DBN1-ZNF346_DBN1_chr5_176893773_ENST00000309007_ZNF346_chr5_176491513_ENST00000506693_length(transcript)=1721nt_BP=991nt
GGGCGGCGCTAGGACCGAGCGAGCGGAGGGAGCGAGCCGGGCGGAGCCAGCGCCCCCCGCCCCCCGCCGGCCGGCTCCCCTCCCCCGGCC
GCTGGCTCGCTCGGCTCGCGACGCTGCAGAGGCTCCGAGGCGGCGGCGGCGACTCCCTCTTTCCCTCCCTCCTCCTCCGTCCGCCCGTCC
GTCCGCGCGTCTGTCCGTTCGGCCCGGTCCGGCCCGAAGCATGGCCGGCGTCAGCTTCAGCGGCCACCGCCTGGAGCTGCTGGCGGCTTA
CGAGGAGGTGATCCGAGAGGAGAGCGCGGCCGACTGGGCTCTGTACACATATGAAGATGGCTCCGATGACCTCAAGCTTGCAGCATCAGG
AGAAGGGGGCTTGCAGGAGCTTTCGGGACACTTTGAGAACCAGAAGGTGATGTACGGCTTCTGCAGTGTCAAGGACTCCCAAGCTGCTCT
GCCAAAATACGTGCTCATCAACTGGGTGGGCGAAGATGTGCCTGATGCCCGCAAGTGCGCTTGTGCCAGCCACGTGGCTAAGGTGGCGGA
GTTCTTCCAGGGTGTCGACGTGATCGTGAACGCCAGCAGCGTGGAAGACATAGACGCGGGTGCCATCGGGCAGCGGCTCTCTAACGGGCT
GGCGCGACTCTCCAGCCCTGTGCTGCACCGACTGCGGCTGCGAGAGGATGAGAACGCAGAGCCCGTGGGCACCACCTACCAGAAGACGGA
TGCAGCTGTGGAAATGAAGCGGATTAACCGAGAGCAGTTCTGGGAGCAGGCCAAGAAGGAAGAAGAGCTGCGGAAGGAGGAGGAGCGGAA
GAAGGCCCTGGATGAGAGGCTCAGGTTCGAGCAGGAGCGGATGGAGCAGGAGCGGCAGGAGCAAGAGGAGCGCGAGCGGCGCTACCGGGA
GCGGGAGCAGCAGATCGAGGAGCACAGGAGGAAACAGCAGACTTTAGAAGCGGAAGAGGCCAAGAGGCGGTTGAAGGAGCAGTCTATCTT
TGTCACCAAAAACAGTGGCATCATCCCTGGGCCAGATTCCAATGCAAAGGCAACCCATTCAGAAAGACTCAACCACCTTGGAAGACTAGA
GGTGATTCTGCCCAGCATCCCATATTGGGCCAGCCATGAGCCAGCTTCCCGTGACTGCTCAGCCCTTGGCTCCCTCTTGCTCGTTGTTCT
CACCAGGAAAGTACACGGGCCTGAGGCAGGATTGGGCCACAGACAGCCTCTCATTGGTCCGGGCTAATTCACTCCTGCTGCTCCCCTTTG
GCAGGGGTCCTGTAGGTCATGACAGGGGAGGCAAGGGTATTGAGAGACTCGGGGTCTCGCGGGGTGGTAGTTTGGAGGGTGGCTTTCCCC
ATTTCCCAACCCCTCTGGGCCTTAGGTGCTGAGGCCCCTGCCACCTGTCTTTCCTCTAAAGGTCAGTTTTGGGCCAGTTCTTGCAACTAA
AGAGCAGAGATCTCTCTGGGCCCTAGACATTTCCAGCAAAACCTGGAACTTTCATGCCAAACCTGGGGCAGGGCAGGAAACAGAGGAAAT
GGCTGCAACATGGGAGCTTGGAGCTAATACGACACTCTGCCTTCCCCCAGAAGGTGCAGGCTTTCCTGAGTCTTAGACCAGATATGGCCA
GTTGCGCAGGTTTCTGCCAACTGTGAAGTATCCTCCTGGAGCAGTGACACAATCTTGGCGGAGCATTGCTACCCCCGCTGCCCCCTCCAC

>21447_21447_4_DBN1-ZNF346_DBN1_chr5_176893773_ENST00000309007_ZNF346_chr5_176491513_ENST00000506693_length(amino acids)=381AA_BP=298
MARSARDAAEAPRRRRRLPLSLPPPPSARPSARLSVRPGPARSMAGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASG
EGGLQELSGHFENQKVMYGFCSVKDSQAALPKYVLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGL
ARLSSPVLHRLRLREDENAEPVGTTYQKTDAAVEMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYRE
REQQIEEHRRKQQTLEAEEAKRRLKEQSIFVTKNSGIIPGPDSNAKATHSERLNHLGRLEVILPSIPYWASHEPASRDCSALGSLLLVVL

--------------------------------------------------------------
>21447_21447_5_DBN1-ZNF346_DBN1_chr5_176893773_ENST00000393565_ZNF346_chr5_176491513_ENST00000358149_length(transcript)=2361nt_BP=887nt
CTCGCGACGCTGCAGAGGCTCCGAGGCGGCGGCGGCGACTCCCTCTTTCCCTCCCTCCTCCTCCGTCCGCCCGTCCGTCCGCGCGTCTGT
CCGTTCGGCCCGGTCCGGCCCGAAGCATGGCCGGCGTCAGCTTCAGCGGCCACCGCCTGGAGCTGCTGGCGGCTTACGAGGAGGTGATCC
GAGAGGAGAGCGCGGCCGACTGGGCTCTGTACACATATGAAGATGGCTCCGATGACCTCAAGCTTGCAGCATCAGGAGAAGGGGGCTTGC
AGGAGCTTTCGGGACACTTTGAGAACCAGAAGGTGATGTACGGCTTCTGCAGTGTCAAGGACTCCCAAGCTGCTCTGCCAAAATACGTGC
TCATCAACTGGGTGGGCGAAGATGTGCCTGATGCCCGCAAGTGCGCTTGTGCCAGCCACGTGGCTAAGGTGGCGGAGTTCTTCCAGGGTG
TCGACGTGATCGTGAACGCCAGCAGCGTGGAAGACATAGACGCGGGTGCCATCGGGCAGCGGCTCTCTAACGGGCTGGCGCGACTCTCCA
GCCCTGTGCTGCACCGACTGCGGCTGCGAGAGGATGAGAACGCAGAGCCCGTGGGCACCACCTACCAGAAGACGGATGCAGCTGTGGAAA
TGAAGCGGATTAACCGAGAGCAGTTCTGGGAGCAGGCCAAGAAGGAAGAAGAGCTGCGGAAGGAGGAGGAGCGGAAGAAGGCCCTGGATG
AGAGGCTCAGGTTCGAGCAGGAGCGGATGGAGCAGGAGCGGCAGGAGCAAGAGGAGCGCGAGCGGCGCTACCGGGAGCGGGAGCAGCAGA
TCGAGGAGCACAGGAGGAAACAGCAGACTTTAGAAGCGGAAGAGGCCAAGAGGCGGTTGAAGGAGCAGTCTATCTTTGTCACCAAAAACA
GTGGCATCATCCCTGGGCCAGATTCCAATGCAAAGGCAACCCATTCAGAAAGACTCAACCACCTTGGAAGACTAGAGGTGATTCTGCCCA
GCATCCCATATTGGGCCAGCCATGAGCCAGCTTCCCGTGACTGCTCAGCCCTTGGCTCCCTCTTGCTCGTTGTTCTCACCAGGAAAGTAC
ACGGGCCTGAGGCAGGATTGGGCCACAGACAGCCTCTCATTGGTCCGGGCTAATTCACTCCTGCTGCTCCCCTTTGGCAGGGGTCCTGTA
GGTCATGACAGGGGAGGCAAGGGTATTGAGAGACTCGGGGTCTCGCGGGGTGGTAGTTTGGAGGGTGGCTTTCCCCATTTCCCAACCCCT
CTGGGCCTTAGGTGCTGAGGCCCCTGCCACCTGTCTTTCCTCTAAAGGTCAGTTTTGGGCCAGTTCTTGCAACTAAAGAGCAGAGATCTC
TCTGGGCCCTAGACATTTCCAGCAAAACCTGGAACTTTCATGCCAAACCTGGGGCAGGGCAGGAAACAGAGGAAATGGCTGCAACATGGG
AGCTTGGAGCTAATACGACACTCTGCCTTCCCCCAGAAGGTGCAGGCTTTCCTGAGTCTTAGACCAGATATGGCCAGTTGCGCAGGTTTC
TGCCAACTGTGAAGTATCCTCCTGGAGCAGTGACACAATCTTGGCGGAGCATTGCTACCCCCGCTGCCCCCTCCACAGTTCCTGAATGGT
GCTAAGGATCTGCAGCAGTTGGCAACGAGCTGGGGCTGGGGGCGGCCTCCATGTCCACTGAGATCATAGGACACTCCAATGGGGATGGGA
CCTTTCCCCTCCTCCATCAGAGGTGCTCTGACCCTAGGTTACACGGGAAAGTGCCCCACATGCAAGTCTCCCTGAGGGTTCTGCCCCTAA
AGGCAGACTGCCTCATGCCCGCTAGCTGTGAGGTTCATTGCTACCCTCGGCCCTACTAGCCCTCTCTTCCCCCTTGTGCAGCGGACCACT
TGCCCAGTTTGCTGTGGTGCTAGCCTTCCCCATCATCCACCGGGTGATTTCTGGGTCCCAGGGAAAGAAAGAGAGAGCTGATGCAGGTTT
CTACAGTGAGGAACAGGCGTTTCCCAGGCCCCACACCCAGATTTCTCTATCTTTGCTGTGTTTTATGGCCTGGGACTGAGTCCACACGGA
TAGATTTTTCCTTGTAACCTTGAGACGAGAATTCCAAGGAGTGTCACCATCAGAGGCTTCTCTTCATTGTGTCAAAGAAGCCCCTAGCTG
CTCTCGTGGCCTCCTTCCCCCACTCCCTATCCCTTCACCTGTGAAATGCCTTTGCTTTGCATATTGTGTGTGGATGTGTGTGTGTGTGTG
TGTGTGTTTGTGTGTATGTGTGTGCTTCTGTGTGTGCCTAATGCTCTGTCTCTTGGTCACTGAAGCATCCAAATAAAGAATTTCCCTCAT

>21447_21447_5_DBN1-ZNF346_DBN1_chr5_176893773_ENST00000393565_ZNF346_chr5_176491513_ENST00000358149_length(amino acids)=348AA_BP=265
MSVRPGPARSMAGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFENQKVMYGFCSVKDSQAALPKY
VLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAV
EMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFVTK

--------------------------------------------------------------
>21447_21447_6_DBN1-ZNF346_DBN1_chr5_176893773_ENST00000393565_ZNF346_chr5_176491513_ENST00000506693_length(transcript)=1617nt_BP=887nt
CTCGCGACGCTGCAGAGGCTCCGAGGCGGCGGCGGCGACTCCCTCTTTCCCTCCCTCCTCCTCCGTCCGCCCGTCCGTCCGCGCGTCTGT
CCGTTCGGCCCGGTCCGGCCCGAAGCATGGCCGGCGTCAGCTTCAGCGGCCACCGCCTGGAGCTGCTGGCGGCTTACGAGGAGGTGATCC
GAGAGGAGAGCGCGGCCGACTGGGCTCTGTACACATATGAAGATGGCTCCGATGACCTCAAGCTTGCAGCATCAGGAGAAGGGGGCTTGC
AGGAGCTTTCGGGACACTTTGAGAACCAGAAGGTGATGTACGGCTTCTGCAGTGTCAAGGACTCCCAAGCTGCTCTGCCAAAATACGTGC
TCATCAACTGGGTGGGCGAAGATGTGCCTGATGCCCGCAAGTGCGCTTGTGCCAGCCACGTGGCTAAGGTGGCGGAGTTCTTCCAGGGTG
TCGACGTGATCGTGAACGCCAGCAGCGTGGAAGACATAGACGCGGGTGCCATCGGGCAGCGGCTCTCTAACGGGCTGGCGCGACTCTCCA
GCCCTGTGCTGCACCGACTGCGGCTGCGAGAGGATGAGAACGCAGAGCCCGTGGGCACCACCTACCAGAAGACGGATGCAGCTGTGGAAA
TGAAGCGGATTAACCGAGAGCAGTTCTGGGAGCAGGCCAAGAAGGAAGAAGAGCTGCGGAAGGAGGAGGAGCGGAAGAAGGCCCTGGATG
AGAGGCTCAGGTTCGAGCAGGAGCGGATGGAGCAGGAGCGGCAGGAGCAAGAGGAGCGCGAGCGGCGCTACCGGGAGCGGGAGCAGCAGA
TCGAGGAGCACAGGAGGAAACAGCAGACTTTAGAAGCGGAAGAGGCCAAGAGGCGGTTGAAGGAGCAGTCTATCTTTGTCACCAAAAACA
GTGGCATCATCCCTGGGCCAGATTCCAATGCAAAGGCAACCCATTCAGAAAGACTCAACCACCTTGGAAGACTAGAGGTGATTCTGCCCA
GCATCCCATATTGGGCCAGCCATGAGCCAGCTTCCCGTGACTGCTCAGCCCTTGGCTCCCTCTTGCTCGTTGTTCTCACCAGGAAAGTAC
ACGGGCCTGAGGCAGGATTGGGCCACAGACAGCCTCTCATTGGTCCGGGCTAATTCACTCCTGCTGCTCCCCTTTGGCAGGGGTCCTGTA
GGTCATGACAGGGGAGGCAAGGGTATTGAGAGACTCGGGGTCTCGCGGGGTGGTAGTTTGGAGGGTGGCTTTCCCCATTTCCCAACCCCT
CTGGGCCTTAGGTGCTGAGGCCCCTGCCACCTGTCTTTCCTCTAAAGGTCAGTTTTGGGCCAGTTCTTGCAACTAAAGAGCAGAGATCTC
TCTGGGCCCTAGACATTTCCAGCAAAACCTGGAACTTTCATGCCAAACCTGGGGCAGGGCAGGAAACAGAGGAAATGGCTGCAACATGGG
AGCTTGGAGCTAATACGACACTCTGCCTTCCCCCAGAAGGTGCAGGCTTTCCTGAGTCTTAGACCAGATATGGCCAGTTGCGCAGGTTTC

>21447_21447_6_DBN1-ZNF346_DBN1_chr5_176893773_ENST00000393565_ZNF346_chr5_176491513_ENST00000506693_length(amino acids)=348AA_BP=265
MSVRPGPARSMAGVSFSGHRLELLAAYEEVIREESAADWALYTYEDGSDDLKLAASGEGGLQELSGHFENQKVMYGFCSVKDSQAALPKY
VLINWVGEDVPDARKCACASHVAKVAEFFQGVDVIVNASSVEDIDAGAIGQRLSNGLARLSSPVLHRLRLREDENAEPVGTTYQKTDAAV
EMKRINREQFWEQAKKEEELRKEEERKKALDERLRFEQERMEQERQEQEERERRYREREQQIEEHRRKQQTLEAEEAKRRLKEQSIFVTK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for DBN1-ZNF346


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DBN1-ZNF346


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DBN1-ZNF346


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource