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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DCTN2-SYT1 (FusionGDB2 ID:21688)

Fusion Gene Summary for DCTN2-SYT1

check button Fusion gene summary
Fusion gene informationFusion gene name: DCTN2-SYT1
Fusion gene ID: 21688
HgeneTgene
Gene symbol

DCTN2

SYT1

Gene ID

10540

6857

Gene namedynactin subunit 2synaptotagmin 1
SynonymsDCTN50|DYNAMITIN|HEL-S-77|RBP50BAGOS|P65|SVP65|SYT
Cytomap

12q13.3

12q21.2

Type of geneprotein-codingprotein-coding
Descriptiondynactin subunit 250 kDa dynein-associated polypeptidedynactin 2 (p50)dynactin complex 50 kDa subunitepididymis secretory protein Li 77epididymis secretory sperm binding proteinp50 dynamitinsynaptotagmin-1synaptotagmin IsytI
Modification date2020031320200313
UniProtAcc

Q13561

.
Ensembl transtripts involved in fusion geneENST00000434715, ENST00000543672, 
ENST00000548249, ENST00000537439, 
ENST00000551400, 		ENST00000549454, 
ENST00000261205, ENST00000393240, 
ENST00000457153, ENST00000552744, 
Fusion gene scores* DoF score15 X 9 X 6=81017 X 12 X 6=1224
# samples 1618
** MAII scorelog2(16/810*10)=-2.33985000288462
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(18/1224*10)=-2.76553474636298
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DCTN2 [Title/Abstract] AND SYT1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDCTN2(57940811)-SYT1(79747282), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSYT1

GO:1903861

positive regulation of dendrite extension

23999003


check buttonFusion gene breakpoints across DCTN2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SYT1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A3M1-01ADCTN2chr12

57940811

-SYT1chr12

79747282

+


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Fusion Gene ORF analysis for DCTN2-SYT1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000434715ENST00000549454DCTN2chr12

57940811

-SYT1chr12

79747282

+
5CDS-intronENST00000543672ENST00000549454DCTN2chr12

57940811

-SYT1chr12

79747282

+
5CDS-intronENST00000548249ENST00000549454DCTN2chr12

57940811

-SYT1chr12

79747282

+
In-frameENST00000434715ENST00000261205DCTN2chr12

57940811

-SYT1chr12

79747282

+
In-frameENST00000434715ENST00000393240DCTN2chr12

57940811

-SYT1chr12

79747282

+
In-frameENST00000434715ENST00000457153DCTN2chr12

57940811

-SYT1chr12

79747282

+
In-frameENST00000434715ENST00000552744DCTN2chr12

57940811

-SYT1chr12

79747282

+
In-frameENST00000543672ENST00000261205DCTN2chr12

57940811

-SYT1chr12

79747282

+
In-frameENST00000543672ENST00000393240DCTN2chr12

57940811

-SYT1chr12

79747282

+
In-frameENST00000543672ENST00000457153DCTN2chr12

57940811

-SYT1chr12

79747282

+
In-frameENST00000543672ENST00000552744DCTN2chr12

57940811

-SYT1chr12

79747282

+
In-frameENST00000548249ENST00000261205DCTN2chr12

57940811

-SYT1chr12

79747282

+
In-frameENST00000548249ENST00000393240DCTN2chr12

57940811

-SYT1chr12

79747282

+
In-frameENST00000548249ENST00000457153DCTN2chr12

57940811

-SYT1chr12

79747282

+
In-frameENST00000548249ENST00000552744DCTN2chr12

57940811

-SYT1chr12

79747282

+
intron-3CDSENST00000537439ENST00000261205DCTN2chr12

57940811

-SYT1chr12

79747282

+
intron-3CDSENST00000537439ENST00000393240DCTN2chr12

57940811

-SYT1chr12

79747282

+
intron-3CDSENST00000537439ENST00000457153DCTN2chr12

57940811

-SYT1chr12

79747282

+
intron-3CDSENST00000537439ENST00000552744DCTN2chr12

57940811

-SYT1chr12

79747282

+
intron-3CDSENST00000551400ENST00000261205DCTN2chr12

57940811

-SYT1chr12

79747282

+
intron-3CDSENST00000551400ENST00000393240DCTN2chr12

57940811

-SYT1chr12

79747282

+
intron-3CDSENST00000551400ENST00000457153DCTN2chr12

57940811

-SYT1chr12

79747282

+
intron-3CDSENST00000551400ENST00000552744DCTN2chr12

57940811

-SYT1chr12

79747282

+
intron-intronENST00000537439ENST00000549454DCTN2chr12

57940811

-SYT1chr12

79747282

+
intron-intronENST00000551400ENST00000549454DCTN2chr12

57940811

-SYT1chr12

79747282

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000548249DCTN2chr1257940811-ENST00000393240SYT1chr1279747282+191830437762241
ENST00000548249DCTN2chr1257940811-ENST00000261205SYT1chr1279747282+364530437762241
ENST00000548249DCTN2chr1257940811-ENST00000457153SYT1chr1279747282+364730437762241
ENST00000548249DCTN2chr1257940811-ENST00000552744SYT1chr1279747282+193330437762241
ENST00000434715DCTN2chr1257940811-ENST00000393240SYT1chr1279747282+172811478572164
ENST00000434715DCTN2chr1257940811-ENST00000261205SYT1chr1279747282+345511478572164
ENST00000434715DCTN2chr1257940811-ENST00000457153SYT1chr1279747282+345711478572164
ENST00000434715DCTN2chr1257940811-ENST00000552744SYT1chr1279747282+174311478572164
ENST00000543672DCTN2chr1257940811-ENST00000393240SYT1chr1279747282+1796182146640164
ENST00000543672DCTN2chr1257940811-ENST00000261205SYT1chr1279747282+3523182146640164
ENST00000543672DCTN2chr1257940811-ENST00000457153SYT1chr1279747282+3525182146640164
ENST00000543672DCTN2chr1257940811-ENST00000552744SYT1chr1279747282+1811182146640164

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000548249ENST00000393240DCTN2chr1257940811-SYT1chr1279747282+0.0010816380.9989184
ENST00000548249ENST00000261205DCTN2chr1257940811-SYT1chr1279747282+0.0002573110.9997427
ENST00000548249ENST00000457153DCTN2chr1257940811-SYT1chr1279747282+0.0002927290.9997073
ENST00000548249ENST00000552744DCTN2chr1257940811-SYT1chr1279747282+0.0011110030.998889
ENST00000434715ENST00000393240DCTN2chr1257940811-SYT1chr1279747282+0.0008298620.9991702
ENST00000434715ENST00000261205DCTN2chr1257940811-SYT1chr1279747282+0.0002975240.9997024
ENST00000434715ENST00000457153DCTN2chr1257940811-SYT1chr1279747282+0.0003399820.99966
ENST00000434715ENST00000552744DCTN2chr1257940811-SYT1chr1279747282+0.0008783780.9991216
ENST00000543672ENST00000393240DCTN2chr1257940811-SYT1chr1279747282+0.0005644550.9994355
ENST00000543672ENST00000261205DCTN2chr1257940811-SYT1chr1279747282+0.0002673710.9997327
ENST00000543672ENST00000457153DCTN2chr1257940811-SYT1chr1279747282+0.0003050310.99969494
ENST00000543672ENST00000552744DCTN2chr1257940811-SYT1chr1279747282+0.0005550250.999445

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Fusion Genomic Features for DCTN2-SYT1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DCTN2chr1257940810-SYT1chr1279747281+0.027177890.97282207
DCTN2chr1257940810-SYT1chr1279747281+0.027177890.97282207

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for DCTN2-SYT1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:57940811/chr12:79747282)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DCTN2

Q13561

.
FUNCTION: Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSYT1chr12:57940811chr12:79747282ENST00000261205711273_406270423.0DomainC2 2
TgeneSYT1chr12:57940811chr12:79747282ENST00000393240812273_406270423.0DomainC2 2
TgeneSYT1chr12:57940811chr12:79747282ENST00000552744610273_406270423.0DomainC2 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDCTN2chr12:57940811chr12:79747282ENST00000434715-116214_24412407.0Coiled coilOntology_term=ECO:0000255
HgeneDCTN2chr12:57940811chr12:79747282ENST00000434715-116379_39912407.0Coiled coilOntology_term=ECO:0000255
HgeneDCTN2chr12:57940811chr12:79747282ENST00000434715-11699_13212407.0Coiled coilOntology_term=ECO:0000255
HgeneDCTN2chr12:57940811chr12:79747282ENST00000548249-114214_24412402.0Coiled coilOntology_term=ECO:0000255
HgeneDCTN2chr12:57940811chr12:79747282ENST00000548249-114379_39912402.0Coiled coilOntology_term=ECO:0000255
HgeneDCTN2chr12:57940811chr12:79747282ENST00000548249-11499_13212402.0Coiled coilOntology_term=ECO:0000255
TgeneSYT1chr12:57940811chr12:79747282ENST00000261205711142_261270423.0DomainC2 1
TgeneSYT1chr12:57940811chr12:79747282ENST00000393240812142_261270423.0DomainC2 1
TgeneSYT1chr12:57940811chr12:79747282ENST00000552744610142_261270423.0DomainC2 1
TgeneSYT1chr12:57940811chr12:79747282ENST00000261205711136_382270423.0RegionPhospholipid binding
TgeneSYT1chr12:57940811chr12:79747282ENST00000393240812136_382270423.0RegionPhospholipid binding
TgeneSYT1chr12:57940811chr12:79747282ENST00000552744610136_382270423.0RegionPhospholipid binding
TgeneSYT1chr12:57940811chr12:79747282ENST000002612057111_57270423.0Topological domainVesicular
TgeneSYT1chr12:57940811chr12:79747282ENST0000026120571181_422270423.0Topological domainCytoplasmic
TgeneSYT1chr12:57940811chr12:79747282ENST000003932408121_57270423.0Topological domainVesicular
TgeneSYT1chr12:57940811chr12:79747282ENST0000039324081281_422270423.0Topological domainCytoplasmic
TgeneSYT1chr12:57940811chr12:79747282ENST000005527446101_57270423.0Topological domainVesicular
TgeneSYT1chr12:57940811chr12:79747282ENST0000055274461081_422270423.0Topological domainCytoplasmic
TgeneSYT1chr12:57940811chr12:79747282ENST0000026120571158_80270423.0TransmembraneHelical
TgeneSYT1chr12:57940811chr12:79747282ENST0000039324081258_80270423.0TransmembraneHelical
TgeneSYT1chr12:57940811chr12:79747282ENST0000055274461058_80270423.0TransmembraneHelical


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Fusion Gene Sequence for DCTN2-SYT1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>21688_21688_1_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000434715_SYT1_chr12_79747282_ENST00000261205_length(transcript)=3455nt_BP=114nt
AACCCAGCCTCTCCCCTACCCGAACACCGGCCCCGGCTCCACCGAGGCCCGGGTCCCCCAGCCCGTCTCGCCGCCGCCATGGCGGACCCT
AAATACGCCGACCTTCCCGGCATTCAAGAGAAATTGGGTGATATCTGCTTCTCCCTTCGCTACGTACCTACTGCTGGTAAGCTGACTGTT
GTCATTCTGGAGGCAAAGAACCTGAAGAAGATGGATGTGGGTGGCTTATCCGATCCTTATGTGAAGATTCATCTGATGCAGAATGGTAAG
AGGCTGAAGAAGAAAAAGACAACAATTAAAAAGAACACACTTAACCCCTACTACAATGAGTCATTCAGCTTTGAAGTACCTTTTGAACAA
ATCCAGAAAGTGCAGGTGGTGGTAACTGTTTTGGACTATGACAAGATTGGCAAGAACGATGCCATCGGCAAAGTCTTTGTGGGCTACAAC
AGCACCGGCGCGGAGCTGCGACACTGGTCAGACATGCTGGCCAACCCCAGGCGACCTATTGCCCAGTGGCACACCCTGCAGGTAGAGGAG
GAAGTTGATGCCATGCTGGCCGTCAAGAAGTAAAGGAAAGAAGAAGCCTTTCTGCATTTGCCCATATAGTGCTCTTTAGCCAGTATCTGT
AAATACCTCAGTAATATGGGTCCTTTCATTTTTCCAGCCATGCATTCCTAACACAATTCAGTGGTACTTGGAATCCTGTTTTAATTTGCA
CAAATTTAAATGTAGAGAGCCCCTAAGTCCTTCATCATACCACTGCCCTCCAAATCTACTCTTCTTTTAAGCAATATGATGTGTAGATAG
AGCATGAATGAAATTATTTATTGTATCACACTGTTGTATATACCAGTATGCTAAAGATTTATTTCTAGTTTGTGTATTTGTATGTTGTAA
GCGTTTCCTAATCTGTGTATATCTAGATGTTTTTAATAAGATGTTCTATTTTAAACTATGTAAATTGACTGAGATATAGGAGAGCTGATA
ATATATTATACGGTAAATATAGTATCGTCTGCATTCCAGCAAAAATATCAACTCGTAAGGCACTAGTACAGTTAAACTGACATCTTAAAG
GACAACTTAAACCTGAGCTTTCTATTGAATCATTTGAGTACCAAGATAAACTTACACCACATACTTGGTGGGTGAATCCAATTTTGTAGA
ATTCCTACACAGGCAAAATAGCATGATCTGAGCAGCAGCATCCAGGCTGACCTCAAGGAAGCATAGCCACAAAACAGAATAGCACCTGTC
TGTACATATTTACAAAGCTAAAATAATGGCTTCACTCTTATATTTGAGGAAGCAACTGAACAGGAGTCAATGATTTCATATTACTGCATA
TAGAATAACAACAAGGTGTTCCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCACATTTGTTTGGGGATGGGGGAGAAGAAGCTA
AGGGGAGAAGTCAACATTTATGAAATATTGCCTGACTATTTAAAAAGAAAAAAGTAGCTCTCCATTATCACCTTTATACAAAATGTACAT
CCTGTGAATTCTGTTCCAGATTTCACACCTACAATAATTCCAAAAGGTTTGCACATTAGAGTTTGTAACAAAATATTTTATTATATAAAA
CCAGGTTAGAAGGAATGCAGGATATTTTTAACACAACAATCTGTGCTTATTACACAAAATTACTTTGTGGTAAACAGACAGTATTGTAAT
CCCATCAAAAGATGAAAGAAAAACAAAAACAAAAACCAACAACAATTAGCCATAGTTCTGAATGCACTTCAATTAAGCCAAAACAGACAG
CTAGTGATCTTTTTATATGCTCTTTTTACTTAAGTTTTAATTTGTCCTTTAAAAAAAGGTGAAACAAACCAAGAACAAGTTCTAGAAAAC
TGAAGCAACCTCTTATGTATACTAGATGCTTGATTTAGGAGGAGTTTTTAAACGTTTTCAATGTTATTATGTAGTAAATGACACTATTAT
GAAGCTACTAGTCATTCCATAAGAGTCTTAAAGGACTGCTCTGTGTAACACTGTGACTGCCGTGTGTGCTTAGACCCGTAGTTTCCTCAG
TGGATAGCACTCAATTTATTCCGTAGTGATATTGTAACAATACTGCCATTCCCTTCTACTGCACTGCCCAAGGTGTGTGTAGCACAAACA
GTTCTCATTACAAAGGACCAATTCAGAACTGAAAAGCTATGCATAGGACAAGGAAGATACATAGAATGGGGTGGAACACAGCATTTTGTC
AAGCACTGTGCAATATTCCATATTTTTCCCCACTATGGTAGACAACCATTTCGTGGAAGGGCAGCCTATTATCCCACACTGCATCTAGCC
TTTTGTCCCATTCACTTCTGTGATCCATTTTAATTTCCAGGCCACAAGACAGTAGTGATGCTCTGAAATGAAAGTTTGTCTTCACAAATA
TCAAAACAAAATGGAGGAAAACTAAGCATTGGCCTCATGTTCAGTCTTCAGGATATCACACCACGTCTTTTCAAAAACTAAAGAGAATTC
AAAAAGGGCTGATGGTAGGCTTTGAACATGGGGTTGGCTGTTTCCCAGTAAAACTGGAATTCCTGTCGTTACTGTTTCCTTATCAAAGAA
GGGGCAAGCTCTTTTGCCTTTTAGGCCAGACATAGCAAACGCTTTATAATTGGCATAGACATAAAGGATAAAAGGAAAATAACCGTCTGC
CGATGGTCCGTACTTCTTAAAAAACATAGGTAATAGAAAATATACACAAGTCAGAATGTGAAATTAAATAATGGTTTGAACAGAAAATTC
AAACAAGACTCTTTCCAATTTAAAGGGCCAAACCCTACCAAAGAGAGGGAGTTGACTGGCTTTTAAAAAGTATTTAAATACCACAAATGA
CATTTAATTTCACTGTATTCAGCTTTAAGTTGTTCACAATGAAACCACACTTTCAAACAAGCAGGTTCAAGCTGCTGAATAGACATTATT
TCTTGCATTAAAATACCACTAATGCATTCTCTTGCAACACTGCCAGACATGGGATTGTCACCATAGAATTAGTTGGTACTATGCCATCTT
TCACTCTTTCACAAGTCAGTGATGGAACCTGCTTTATGACCAAGATTCATCCTCAAATAAGCCACATGTACCCTTCTGACAAAGCTGTGT
AAAGTATTAGAATCTGATGCTCTAGAAAGATCCTAGTTGCCTTTGTGTATATTTACTGCCTGCTTGAGTGTTTCTATGTGTGGGTTTTCC
CTGTATCTTGTAGAAATGTTGGGGTGTTTTCCTCTGCCATATGGCTCGTGGCCTGCGAGCCAACTATTTCAGCTGTATTTTACCTTCATT
TTTGATGAGGTGATTTAAATTTTGTTTCACTTTGTGTAGTGAATTCCACAGTAGTTTTCTGATTGTTGTTAAAAATGACTTAACATATTA

>21688_21688_1_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000434715_SYT1_chr12_79747282_ENST00000261205_length(amino acids)=164AA_BP=12
MADPKYADLPGIQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV

--------------------------------------------------------------
>21688_21688_2_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000434715_SYT1_chr12_79747282_ENST00000393240_length(transcript)=1728nt_BP=114nt
AACCCAGCCTCTCCCCTACCCGAACACCGGCCCCGGCTCCACCGAGGCCCGGGTCCCCCAGCCCGTCTCGCCGCCGCCATGGCGGACCCT
AAATACGCCGACCTTCCCGGCATTCAAGAGAAATTGGGTGATATCTGCTTCTCCCTTCGCTACGTACCTACTGCTGGTAAGCTGACTGTT
GTCATTCTGGAGGCAAAGAACCTGAAGAAGATGGATGTGGGTGGCTTATCCGATCCTTATGTGAAGATTCATCTGATGCAGAATGGTAAG
AGGCTGAAGAAGAAAAAGACAACAATTAAAAAGAACACACTTAACCCCTACTACAATGAGTCATTCAGCTTTGAAGTACCTTTTGAACAA
ATCCAGAAAGTGCAGGTGGTGGTAACTGTTTTGGACTATGACAAGATTGGCAAGAACGATGCCATCGGCAAAGTCTTTGTGGGCTACAAC
AGCACCGGCGCGGAGCTGCGACACTGGTCAGACATGCTGGCCAACCCCAGGCGACCTATTGCCCAGTGGCACACCCTGCAGGTAGAGGAG
GAAGTTGATGCCATGCTGGCCGTCAAGAAGTAAAGGAAAGAAGAAGCCTTTCTGCATTTGCCCATATAGTGCTCTTTAGCCAGTATCTGT
AAATACCTCAGTAATATGGGTCCTTTCATTTTTCCAGCCATGCATTCCTAACACAATTCAGTGGTACTTGGAATCCTGTTTTAATTTGCA
CAAATTTAAATGTAGAGAGCCCCTAAGTCCTTCATCATACCACTGCCCTCCAAATCTACTCTTCTTTTAAGCAATATGATGTGTAGATAG
AGCATGAATGAAATTATTTATTGTATCACACTGTTGTATATACCAGTATGCTAAAGATTTATTTCTAGTTTGTGTATTTGTATGTTGTAA
GCGTTTCCTAATCTGTGTATATCTAGATGTTTTTAATAAGATGTTCTATTTTAAACTATGTAAATTGACTGAGATATAGGAGAGCTGATA
ATATATTATACGGTAAATATAGTATCGTCTGCATTCCAGCAAAAATATCAACTCGTAAGGCACTAGTACAGTTAAACTGACATCTTAAAG
GACAACTTAAACCTGAGCTTTCTATTGAATCATTTGAGTACCAAGATAAACTTACACCACATACTTGGTGGGTGAATCCAATTTTGTAGA
ATTCCTACACAGGCAAAATAGCATGATCTGAGCAGCAGCATCCAGGCTGACCTCAAGGAAGCATAGCCACAAAACAGAATAGCACCTGTC
TGTACATATTTACAAAGCTAAAATAATGGCTTCACTCTTATATTTGAGGAAGCAACTGAACAGGAGTCAATGATTTCATATTACTGCATA
TAGAATAACAACAAGGTGTTCCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCACATTTGTTTGGGGATGGGGGAGAAGAAGCTA
AGGGGAGAAGTCAACATTTATGAAATATTGCCTGACTATTTAAAAAGAAAAAAGTAGCTCTCCATTATCACCTTTATACAAAATGTACAT
CCTGTGAATTCTGTTCCAGATTTCACACCTACAATAATTCCAAAAGGTTTGCACATTAGAGTTTGTAACAAAATATTTTATTATATAAAA
CCAGGTTAGAAGGAATGCAGGATATTTTTAACACAACAATCTGTGCTTATTACACAAAATTACTTTGTGGTAAACAGACAGTATTGTAAT

>21688_21688_2_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000434715_SYT1_chr12_79747282_ENST00000393240_length(amino acids)=164AA_BP=12
MADPKYADLPGIQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV

--------------------------------------------------------------
>21688_21688_3_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000434715_SYT1_chr12_79747282_ENST00000457153_length(transcript)=3457nt_BP=114nt
AACCCAGCCTCTCCCCTACCCGAACACCGGCCCCGGCTCCACCGAGGCCCGGGTCCCCCAGCCCGTCTCGCCGCCGCCATGGCGGACCCT
AAATACGCCGACCTTCCCGGCATTCAAGAGAAATTGGGTGATATCTGCTTCTCCCTTCGCTACGTACCTACTGCTGGTAAGCTGACTGTT
GTCATTCTGGAGGCAAAGAACCTGAAGAAGATGGATGTGGGTGGCTTATCCGATCCTTATGTGAAGATTCATCTGATGCAGAATGGTAAG
AGGCTGAAGAAGAAAAAGACAACAATTAAAAAGAACACACTTAACCCCTACTACAATGAGTCATTCAGCTTTGAAGTACCTTTTGAACAA
ATCCAGAAAGTGCAGGTGGTGGTAACTGTTTTGGACTATGACAAGATTGGCAAGAACGATGCCATCGGCAAAGTCTTTGTGGGCTACAAC
AGCACCGGCGCGGAGCTGCGACACTGGTCAGACATGCTGGCCAACCCCAGGCGACCTATTGCCCAGTGGCACACCCTGCAGGTAGAGGAG
GAAGTTGATGCCATGCTGGCCGTCAAGAAGTAAAGGAAAGAAGAAGCCTTTCTGCATTTGCCCATATAGTGCTCTTTAGCCAGTATCTGT
AAATACCTCAGTAATATGGGTCCTTTCATTTTTCCAGCCATGCATTCCTAACACAATTCAGTGGTACTTGGAATCCTGTTTTAATTTGCA
CAAATTTAAATGTAGAGAGCCCCTAAGTCCTTCATCATACCACTGCCCTCCAAATCTACTCTTCTTTTAAGCAATATGATGTGTAGATAG
AGCATGAATGAAATTATTTATTGTATCACACTGTTGTATATACCAGTATGCTAAAGATTTATTTCTAGTTTGTGTATTTGTATGTTGTAA
GCGTTTCCTAATCTGTGTATATCTAGATGTTTTTAATAAGATGTTCTATTTTAAACTATGTAAATTGACTGAGATATAGGAGAGCTGATA
ATATATTATACGGTAAATATAGTATCGTCTGCATTCCAGCAAAAATATCAACTCGTAAGGCACTAGTACAGTTAAACTGACATCTTAAAG
GACAACTTAAACCTGAGCTTTCTATTGAATCATTTGAGTACCAAGATAAACTTACACCACATACTTGGTGGGTGAATCCAATTTTGTAGA
ATTCCTACACAGGCAAAATAGCATGATCTGAGCAGCAGCATCCAGGCTGACCTCAAGGAAGCATAGCCACAAAACAGAATAGCACCTGTC
TGTACATATTTACAAAGCTAAAATAATGGCTTCACTCTTATATTTGAGGAAGCAACTGAACAGGAGTCAATGATTTCATATTACTGCATA
TAGAATAACAACAAGGTGTTCCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCACATTTGTTTGGGGATGGGGGAGAAGAAGCTA
AGGGGAGAAGTCAACATTTATGAAATATTGCCTGACTATTTAAAAAGAAAAAAGTAGCTCTCCATTATCACCTTTATACAAAATGTACAT
CCTGTGAATTCTGTTCCAGATTTCACACCTACAATAATTCCAAAAGGTTTGCACATTAGAGTTTGTAACAAAATATTTTATTATATAAAA
CCAGGTTAGAAGGAATGCAGGATATTTTTAACACAACAATCTGTGCTTATTACACAAAATTACTTTGTGGTAAACAGACAGTATTGTAAT
CCCATCAAAAGATGAAAGAAAAACAAAAACAAAAACCAACAACAATTAGCCATAGTTCTGAATGCACTTCAATTAAGCCAAAACAGACAG
CTAGTGATCTTTTTATATGCTCTTTTTACTTAAGTTTTAATTTGTCCTTTAAAAAAAGGTGAAACAAACCAAGAACAAGTTCTAGAAAAC
TGAAGCAACCTCTTATGTATACTAGATGCTTGATTTAGGAGGAGTTTTTAAACGTTTTCAATGTTATTATGTAGTAAATGACACTATTAT
GAAGCTACTAGTCATTCCATAAGAGTCTTAAAGGACTGCTCTGTGTAACACTGTGACTGCCGTGTGTGCTTAGACCCGTAGTTTCCTCAG
TGGATAGCACTCAATTTATTCCGTAGTGATATTGTAACAATACTGCCATTCCCTTCTACTGCACTGCCCAAGGTGTGTGTAGCACAAACA
GTTCTCATTACAAAGGACCAATTCAGAACTGAAAAGCTATGCATAGGACAAGGAAGATACATAGAATGGGGTGGAACACAGCATTTTGTC
AAGCACTGTGCAATATTCCATATTTTTCCCCACTATGGTAGACAACCATTTCGTGGAAGGGCAGCCTATTATCCCACACTGCATCTAGCC
TTTTGTCCCATTCACTTCTGTGATCCATTTTAATTTCCAGGCCACAAGACAGTAGTGATGCTCTGAAATGAAAGTTTGTCTTCACAAATA
TCAAAACAAAATGGAGGAAAACTAAGCATTGGCCTCATGTTCAGTCTTCAGGATATCACACCACGTCTTTTCAAAAACTAAAGAGAATTC
AAAAAGGGCTGATGGTAGGCTTTGAACATGGGGTTGGCTGTTTCCCAGTAAAACTGGAATTCCTGTCGTTACTGTTTCCTTATCAAAGAA
GGGGCAAGCTCTTTTGCCTTTTAGGCCAGACATAGCAAACGCTTTATAATTGGCATAGACATAAAGGATAAAAGGAAAATAACCGTCTGC
CGATGGTCCGTACTTCTTAAAAAACATAGGTAATAGAAAATATACACAAGTCAGAATGTGAAATTAAATAATGGTTTGAACAGAAAATTC
AAACAAGACTCTTTCCAATTTAAAGGGCCAAACCCTACCAAAGAGAGGGAGTTGACTGGCTTTTAAAAAGTATTTAAATACCACAAATGA
CATTTAATTTCACTGTATTCAGCTTTAAGTTGTTCACAATGAAACCACACTTTCAAACAAGCAGGTTCAAGCTGCTGAATAGACATTATT
TCTTGCATTAAAATACCACTAATGCATTCTCTTGCAACACTGCCAGACATGGGATTGTCACCATAGAATTAGTTGGTACTATGCCATCTT
TCACTCTTTCACAAGTCAGTGATGGAACCTGCTTTATGACCAAGATTCATCCTCAAATAAGCCACATGTACCCTTCTGACAAAGCTGTGT
AAAGTATTAGAATCTGATGCTCTAGAAAGATCCTAGTTGCCTTTGTGTATATTTACTGCCTGCTTGAGTGTTTCTATGTGTGGGTTTTCC
CTGTATCTTGTAGAAATGTTGGGGTGTTTTCCTCTGCCATATGGCTCGTGGCCTGCGAGCCAACTATTTCAGCTGTATTTTACCTTCATT
TTTGATGAGGTGATTTAAATTTTGTTTCACTTTGTGTAGTGAATTCCACAGTAGTTTTCTGATTGTTGTTAAAAATGACTTAACATATTA

>21688_21688_3_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000434715_SYT1_chr12_79747282_ENST00000457153_length(amino acids)=164AA_BP=12
MADPKYADLPGIQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV

--------------------------------------------------------------
>21688_21688_4_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000434715_SYT1_chr12_79747282_ENST00000552744_length(transcript)=1743nt_BP=114nt
AACCCAGCCTCTCCCCTACCCGAACACCGGCCCCGGCTCCACCGAGGCCCGGGTCCCCCAGCCCGTCTCGCCGCCGCCATGGCGGACCCT
AAATACGCCGACCTTCCCGGCATTCAAGAGAAATTGGGTGATATCTGCTTCTCCCTTCGCTACGTACCTACTGCTGGTAAGCTGACTGTT
GTCATTCTGGAGGCAAAGAACCTGAAGAAGATGGATGTGGGTGGCTTATCCGATCCTTATGTGAAGATTCATCTGATGCAGAATGGTAAG
AGGCTGAAGAAGAAAAAGACAACAATTAAAAAGAACACACTTAACCCCTACTACAATGAGTCATTCAGCTTTGAAGTACCTTTTGAACAA
ATCCAGAAAGTGCAGGTGGTGGTAACTGTTTTGGACTATGACAAGATTGGCAAGAACGATGCCATCGGCAAAGTCTTTGTGGGCTACAAC
AGCACCGGCGCGGAGCTGCGACACTGGTCAGACATGCTGGCCAACCCCAGGCGACCTATTGCCCAGTGGCACACCCTGCAGGTAGAGGAG
GAAGTTGATGCCATGCTGGCCGTCAAGAAGTAAAGGAAAGAAGAAGCCTTTCTGCATTTGCCCATATAGTGCTCTTTAGCCAGTATCTGT
AAATACCTCAGTAATATGGGTCCTTTCATTTTTCCAGCCATGCATTCCTAACACAATTCAGTGGTACTTGGAATCCTGTTTTAATTTGCA
CAAATTTAAATGTAGAGAGCCCCTAAGTCCTTCATCATACCACTGCCCTCCAAATCTACTCTTCTTTTAAGCAATATGATGTGTAGATAG
AGCATGAATGAAATTATTTATTGTATCACACTGTTGTATATACCAGTATGCTAAAGATTTATTTCTAGTTTGTGTATTTGTATGTTGTAA
GCGTTTCCTAATCTGTGTATATCTAGATGTTTTTAATAAGATGTTCTATTTTAAACTATGTAAATTGACTGAGATATAGGAGAGCTGATA
ATATATTATACGGTAAATATAGTATCGTCTGCATTCCAGCAAAAATATCAACTCGTAAGGCACTAGTACAGTTAAACTGACATCTTAAAG
GACAACTTAAACCTGAGCTTTCTATTGAATCATTTGAGTACCAAGATAAACTTACACCACATACTTGGTGGGTGAATCCAATTTTGTAGA
ATTCCTACACAGGCAAAATAGCATGATCTGAGCAGCAGCATCCAGGCTGACCTCAAGGAAGCATAGCCACAAAACAGAATAGCACCTGTC
TGTACATATTTACAAAGCTAAAATAATGGCTTCACTCTTATATTTGAGGAAGCAACTGAACAGGAGTCAATGATTTCATATTACTGCATA
TAGAATAACAACAAGGTGTTCCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCACATTTGTTTGGGGATGGGGGAGAAGAAGCTA
AGGGGAGAAGTCAACATTTATGAAATATTGCCTGACTATTTAAAAAGAAAAAAGTAGCTCTCCATTATCACCTTTATACAAAATGTACAT
CCTGTGAATTCTGTTCCAGATTTCACACCTACAATAATTCCAAAAGGTTTGCACATTAGAGTTTGTAACAAAATATTTTATTATATAAAA
CCAGGTTAGAAGGAATGCAGGATATTTTTAACACAACAATCTGTGCTTATTACACAAAATTACTTTGTGGTAAACAGACAGTATTGTAAT

>21688_21688_4_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000434715_SYT1_chr12_79747282_ENST00000552744_length(amino acids)=164AA_BP=12
MADPKYADLPGIQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV

--------------------------------------------------------------
>21688_21688_5_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000543672_SYT1_chr12_79747282_ENST00000261205_length(transcript)=3523nt_BP=182nt
GCTACTGCTGTCGCGAGACTTCCTGCTCATCTGCCGCTCCCTTTGCCGCCGCCTTAGCCCGGGACCCGAACCCAGCCTCTCCCCTACCCG
AACACCGGCCCCGGCTCCACCGAGGCCCGGGTCCCCCAGCCCGTCTCGCCGCCGCCATGGCGGACCCTAAATACGCCGACCTTCCCGGCA
TTCAAGAGAAATTGGGTGATATCTGCTTCTCCCTTCGCTACGTACCTACTGCTGGTAAGCTGACTGTTGTCATTCTGGAGGCAAAGAACC
TGAAGAAGATGGATGTGGGTGGCTTATCCGATCCTTATGTGAAGATTCATCTGATGCAGAATGGTAAGAGGCTGAAGAAGAAAAAGACAA
CAATTAAAAAGAACACACTTAACCCCTACTACAATGAGTCATTCAGCTTTGAAGTACCTTTTGAACAAATCCAGAAAGTGCAGGTGGTGG
TAACTGTTTTGGACTATGACAAGATTGGCAAGAACGATGCCATCGGCAAAGTCTTTGTGGGCTACAACAGCACCGGCGCGGAGCTGCGAC
ACTGGTCAGACATGCTGGCCAACCCCAGGCGACCTATTGCCCAGTGGCACACCCTGCAGGTAGAGGAGGAAGTTGATGCCATGCTGGCCG
TCAAGAAGTAAAGGAAAGAAGAAGCCTTTCTGCATTTGCCCATATAGTGCTCTTTAGCCAGTATCTGTAAATACCTCAGTAATATGGGTC
CTTTCATTTTTCCAGCCATGCATTCCTAACACAATTCAGTGGTACTTGGAATCCTGTTTTAATTTGCACAAATTTAAATGTAGAGAGCCC
CTAAGTCCTTCATCATACCACTGCCCTCCAAATCTACTCTTCTTTTAAGCAATATGATGTGTAGATAGAGCATGAATGAAATTATTTATT
GTATCACACTGTTGTATATACCAGTATGCTAAAGATTTATTTCTAGTTTGTGTATTTGTATGTTGTAAGCGTTTCCTAATCTGTGTATAT
CTAGATGTTTTTAATAAGATGTTCTATTTTAAACTATGTAAATTGACTGAGATATAGGAGAGCTGATAATATATTATACGGTAAATATAG
TATCGTCTGCATTCCAGCAAAAATATCAACTCGTAAGGCACTAGTACAGTTAAACTGACATCTTAAAGGACAACTTAAACCTGAGCTTTC
TATTGAATCATTTGAGTACCAAGATAAACTTACACCACATACTTGGTGGGTGAATCCAATTTTGTAGAATTCCTACACAGGCAAAATAGC
ATGATCTGAGCAGCAGCATCCAGGCTGACCTCAAGGAAGCATAGCCACAAAACAGAATAGCACCTGTCTGTACATATTTACAAAGCTAAA
ATAATGGCTTCACTCTTATATTTGAGGAAGCAACTGAACAGGAGTCAATGATTTCATATTACTGCATATAGAATAACAACAAGGTGTTCC
GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCACATTTGTTTGGGGATGGGGGAGAAGAAGCTAAGGGGAGAAGTCAACATTTATG
AAATATTGCCTGACTATTTAAAAAGAAAAAAGTAGCTCTCCATTATCACCTTTATACAAAATGTACATCCTGTGAATTCTGTTCCAGATT
TCACACCTACAATAATTCCAAAAGGTTTGCACATTAGAGTTTGTAACAAAATATTTTATTATATAAAACCAGGTTAGAAGGAATGCAGGA
TATTTTTAACACAACAATCTGTGCTTATTACACAAAATTACTTTGTGGTAAACAGACAGTATTGTAATCCCATCAAAAGATGAAAGAAAA
ACAAAAACAAAAACCAACAACAATTAGCCATAGTTCTGAATGCACTTCAATTAAGCCAAAACAGACAGCTAGTGATCTTTTTATATGCTC
TTTTTACTTAAGTTTTAATTTGTCCTTTAAAAAAAGGTGAAACAAACCAAGAACAAGTTCTAGAAAACTGAAGCAACCTCTTATGTATAC
TAGATGCTTGATTTAGGAGGAGTTTTTAAACGTTTTCAATGTTATTATGTAGTAAATGACACTATTATGAAGCTACTAGTCATTCCATAA
GAGTCTTAAAGGACTGCTCTGTGTAACACTGTGACTGCCGTGTGTGCTTAGACCCGTAGTTTCCTCAGTGGATAGCACTCAATTTATTCC
GTAGTGATATTGTAACAATACTGCCATTCCCTTCTACTGCACTGCCCAAGGTGTGTGTAGCACAAACAGTTCTCATTACAAAGGACCAAT
TCAGAACTGAAAAGCTATGCATAGGACAAGGAAGATACATAGAATGGGGTGGAACACAGCATTTTGTCAAGCACTGTGCAATATTCCATA
TTTTTCCCCACTATGGTAGACAACCATTTCGTGGAAGGGCAGCCTATTATCCCACACTGCATCTAGCCTTTTGTCCCATTCACTTCTGTG
ATCCATTTTAATTTCCAGGCCACAAGACAGTAGTGATGCTCTGAAATGAAAGTTTGTCTTCACAAATATCAAAACAAAATGGAGGAAAAC
TAAGCATTGGCCTCATGTTCAGTCTTCAGGATATCACACCACGTCTTTTCAAAAACTAAAGAGAATTCAAAAAGGGCTGATGGTAGGCTT
TGAACATGGGGTTGGCTGTTTCCCAGTAAAACTGGAATTCCTGTCGTTACTGTTTCCTTATCAAAGAAGGGGCAAGCTCTTTTGCCTTTT
AGGCCAGACATAGCAAACGCTTTATAATTGGCATAGACATAAAGGATAAAAGGAAAATAACCGTCTGCCGATGGTCCGTACTTCTTAAAA
AACATAGGTAATAGAAAATATACACAAGTCAGAATGTGAAATTAAATAATGGTTTGAACAGAAAATTCAAACAAGACTCTTTCCAATTTA
AAGGGCCAAACCCTACCAAAGAGAGGGAGTTGACTGGCTTTTAAAAAGTATTTAAATACCACAAATGACATTTAATTTCACTGTATTCAG
CTTTAAGTTGTTCACAATGAAACCACACTTTCAAACAAGCAGGTTCAAGCTGCTGAATAGACATTATTTCTTGCATTAAAATACCACTAA
TGCATTCTCTTGCAACACTGCCAGACATGGGATTGTCACCATAGAATTAGTTGGTACTATGCCATCTTTCACTCTTTCACAAGTCAGTGA
TGGAACCTGCTTTATGACCAAGATTCATCCTCAAATAAGCCACATGTACCCTTCTGACAAAGCTGTGTAAAGTATTAGAATCTGATGCTC
TAGAAAGATCCTAGTTGCCTTTGTGTATATTTACTGCCTGCTTGAGTGTTTCTATGTGTGGGTTTTCCCTGTATCTTGTAGAAATGTTGG
GGTGTTTTCCTCTGCCATATGGCTCGTGGCCTGCGAGCCAACTATTTCAGCTGTATTTTACCTTCATTTTTGATGAGGTGATTTAAATTT
TGTTTCACTTTGTGTAGTGAATTCCACAGTAGTTTTCTGATTGTTGTTAAAAATGACTTAACATATTACACAGATATTCAATAAAAATGT

>21688_21688_5_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000543672_SYT1_chr12_79747282_ENST00000261205_length(amino acids)=164AA_BP=12
MADPKYADLPGIQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV

--------------------------------------------------------------
>21688_21688_6_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000543672_SYT1_chr12_79747282_ENST00000393240_length(transcript)=1796nt_BP=182nt
GCTACTGCTGTCGCGAGACTTCCTGCTCATCTGCCGCTCCCTTTGCCGCCGCCTTAGCCCGGGACCCGAACCCAGCCTCTCCCCTACCCG
AACACCGGCCCCGGCTCCACCGAGGCCCGGGTCCCCCAGCCCGTCTCGCCGCCGCCATGGCGGACCCTAAATACGCCGACCTTCCCGGCA
TTCAAGAGAAATTGGGTGATATCTGCTTCTCCCTTCGCTACGTACCTACTGCTGGTAAGCTGACTGTTGTCATTCTGGAGGCAAAGAACC
TGAAGAAGATGGATGTGGGTGGCTTATCCGATCCTTATGTGAAGATTCATCTGATGCAGAATGGTAAGAGGCTGAAGAAGAAAAAGACAA
CAATTAAAAAGAACACACTTAACCCCTACTACAATGAGTCATTCAGCTTTGAAGTACCTTTTGAACAAATCCAGAAAGTGCAGGTGGTGG
TAACTGTTTTGGACTATGACAAGATTGGCAAGAACGATGCCATCGGCAAAGTCTTTGTGGGCTACAACAGCACCGGCGCGGAGCTGCGAC
ACTGGTCAGACATGCTGGCCAACCCCAGGCGACCTATTGCCCAGTGGCACACCCTGCAGGTAGAGGAGGAAGTTGATGCCATGCTGGCCG
TCAAGAAGTAAAGGAAAGAAGAAGCCTTTCTGCATTTGCCCATATAGTGCTCTTTAGCCAGTATCTGTAAATACCTCAGTAATATGGGTC
CTTTCATTTTTCCAGCCATGCATTCCTAACACAATTCAGTGGTACTTGGAATCCTGTTTTAATTTGCACAAATTTAAATGTAGAGAGCCC
CTAAGTCCTTCATCATACCACTGCCCTCCAAATCTACTCTTCTTTTAAGCAATATGATGTGTAGATAGAGCATGAATGAAATTATTTATT
GTATCACACTGTTGTATATACCAGTATGCTAAAGATTTATTTCTAGTTTGTGTATTTGTATGTTGTAAGCGTTTCCTAATCTGTGTATAT
CTAGATGTTTTTAATAAGATGTTCTATTTTAAACTATGTAAATTGACTGAGATATAGGAGAGCTGATAATATATTATACGGTAAATATAG
TATCGTCTGCATTCCAGCAAAAATATCAACTCGTAAGGCACTAGTACAGTTAAACTGACATCTTAAAGGACAACTTAAACCTGAGCTTTC
TATTGAATCATTTGAGTACCAAGATAAACTTACACCACATACTTGGTGGGTGAATCCAATTTTGTAGAATTCCTACACAGGCAAAATAGC
ATGATCTGAGCAGCAGCATCCAGGCTGACCTCAAGGAAGCATAGCCACAAAACAGAATAGCACCTGTCTGTACATATTTACAAAGCTAAA
ATAATGGCTTCACTCTTATATTTGAGGAAGCAACTGAACAGGAGTCAATGATTTCATATTACTGCATATAGAATAACAACAAGGTGTTCC
GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCACATTTGTTTGGGGATGGGGGAGAAGAAGCTAAGGGGAGAAGTCAACATTTATG
AAATATTGCCTGACTATTTAAAAAGAAAAAAGTAGCTCTCCATTATCACCTTTATACAAAATGTACATCCTGTGAATTCTGTTCCAGATT
TCACACCTACAATAATTCCAAAAGGTTTGCACATTAGAGTTTGTAACAAAATATTTTATTATATAAAACCAGGTTAGAAGGAATGCAGGA

>21688_21688_6_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000543672_SYT1_chr12_79747282_ENST00000393240_length(amino acids)=164AA_BP=12
MADPKYADLPGIQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV

--------------------------------------------------------------
>21688_21688_7_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000543672_SYT1_chr12_79747282_ENST00000457153_length(transcript)=3525nt_BP=182nt
GCTACTGCTGTCGCGAGACTTCCTGCTCATCTGCCGCTCCCTTTGCCGCCGCCTTAGCCCGGGACCCGAACCCAGCCTCTCCCCTACCCG
AACACCGGCCCCGGCTCCACCGAGGCCCGGGTCCCCCAGCCCGTCTCGCCGCCGCCATGGCGGACCCTAAATACGCCGACCTTCCCGGCA
TTCAAGAGAAATTGGGTGATATCTGCTTCTCCCTTCGCTACGTACCTACTGCTGGTAAGCTGACTGTTGTCATTCTGGAGGCAAAGAACC
TGAAGAAGATGGATGTGGGTGGCTTATCCGATCCTTATGTGAAGATTCATCTGATGCAGAATGGTAAGAGGCTGAAGAAGAAAAAGACAA
CAATTAAAAAGAACACACTTAACCCCTACTACAATGAGTCATTCAGCTTTGAAGTACCTTTTGAACAAATCCAGAAAGTGCAGGTGGTGG
TAACTGTTTTGGACTATGACAAGATTGGCAAGAACGATGCCATCGGCAAAGTCTTTGTGGGCTACAACAGCACCGGCGCGGAGCTGCGAC
ACTGGTCAGACATGCTGGCCAACCCCAGGCGACCTATTGCCCAGTGGCACACCCTGCAGGTAGAGGAGGAAGTTGATGCCATGCTGGCCG
TCAAGAAGTAAAGGAAAGAAGAAGCCTTTCTGCATTTGCCCATATAGTGCTCTTTAGCCAGTATCTGTAAATACCTCAGTAATATGGGTC
CTTTCATTTTTCCAGCCATGCATTCCTAACACAATTCAGTGGTACTTGGAATCCTGTTTTAATTTGCACAAATTTAAATGTAGAGAGCCC
CTAAGTCCTTCATCATACCACTGCCCTCCAAATCTACTCTTCTTTTAAGCAATATGATGTGTAGATAGAGCATGAATGAAATTATTTATT
GTATCACACTGTTGTATATACCAGTATGCTAAAGATTTATTTCTAGTTTGTGTATTTGTATGTTGTAAGCGTTTCCTAATCTGTGTATAT
CTAGATGTTTTTAATAAGATGTTCTATTTTAAACTATGTAAATTGACTGAGATATAGGAGAGCTGATAATATATTATACGGTAAATATAG
TATCGTCTGCATTCCAGCAAAAATATCAACTCGTAAGGCACTAGTACAGTTAAACTGACATCTTAAAGGACAACTTAAACCTGAGCTTTC
TATTGAATCATTTGAGTACCAAGATAAACTTACACCACATACTTGGTGGGTGAATCCAATTTTGTAGAATTCCTACACAGGCAAAATAGC
ATGATCTGAGCAGCAGCATCCAGGCTGACCTCAAGGAAGCATAGCCACAAAACAGAATAGCACCTGTCTGTACATATTTACAAAGCTAAA
ATAATGGCTTCACTCTTATATTTGAGGAAGCAACTGAACAGGAGTCAATGATTTCATATTACTGCATATAGAATAACAACAAGGTGTTCC
GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCACATTTGTTTGGGGATGGGGGAGAAGAAGCTAAGGGGAGAAGTCAACATTTATG
AAATATTGCCTGACTATTTAAAAAGAAAAAAGTAGCTCTCCATTATCACCTTTATACAAAATGTACATCCTGTGAATTCTGTTCCAGATT
TCACACCTACAATAATTCCAAAAGGTTTGCACATTAGAGTTTGTAACAAAATATTTTATTATATAAAACCAGGTTAGAAGGAATGCAGGA
TATTTTTAACACAACAATCTGTGCTTATTACACAAAATTACTTTGTGGTAAACAGACAGTATTGTAATCCCATCAAAAGATGAAAGAAAA
ACAAAAACAAAAACCAACAACAATTAGCCATAGTTCTGAATGCACTTCAATTAAGCCAAAACAGACAGCTAGTGATCTTTTTATATGCTC
TTTTTACTTAAGTTTTAATTTGTCCTTTAAAAAAAGGTGAAACAAACCAAGAACAAGTTCTAGAAAACTGAAGCAACCTCTTATGTATAC
TAGATGCTTGATTTAGGAGGAGTTTTTAAACGTTTTCAATGTTATTATGTAGTAAATGACACTATTATGAAGCTACTAGTCATTCCATAA
GAGTCTTAAAGGACTGCTCTGTGTAACACTGTGACTGCCGTGTGTGCTTAGACCCGTAGTTTCCTCAGTGGATAGCACTCAATTTATTCC
GTAGTGATATTGTAACAATACTGCCATTCCCTTCTACTGCACTGCCCAAGGTGTGTGTAGCACAAACAGTTCTCATTACAAAGGACCAAT
TCAGAACTGAAAAGCTATGCATAGGACAAGGAAGATACATAGAATGGGGTGGAACACAGCATTTTGTCAAGCACTGTGCAATATTCCATA
TTTTTCCCCACTATGGTAGACAACCATTTCGTGGAAGGGCAGCCTATTATCCCACACTGCATCTAGCCTTTTGTCCCATTCACTTCTGTG
ATCCATTTTAATTTCCAGGCCACAAGACAGTAGTGATGCTCTGAAATGAAAGTTTGTCTTCACAAATATCAAAACAAAATGGAGGAAAAC
TAAGCATTGGCCTCATGTTCAGTCTTCAGGATATCACACCACGTCTTTTCAAAAACTAAAGAGAATTCAAAAAGGGCTGATGGTAGGCTT
TGAACATGGGGTTGGCTGTTTCCCAGTAAAACTGGAATTCCTGTCGTTACTGTTTCCTTATCAAAGAAGGGGCAAGCTCTTTTGCCTTTT
AGGCCAGACATAGCAAACGCTTTATAATTGGCATAGACATAAAGGATAAAAGGAAAATAACCGTCTGCCGATGGTCCGTACTTCTTAAAA
AACATAGGTAATAGAAAATATACACAAGTCAGAATGTGAAATTAAATAATGGTTTGAACAGAAAATTCAAACAAGACTCTTTCCAATTTA
AAGGGCCAAACCCTACCAAAGAGAGGGAGTTGACTGGCTTTTAAAAAGTATTTAAATACCACAAATGACATTTAATTTCACTGTATTCAG
CTTTAAGTTGTTCACAATGAAACCACACTTTCAAACAAGCAGGTTCAAGCTGCTGAATAGACATTATTTCTTGCATTAAAATACCACTAA
TGCATTCTCTTGCAACACTGCCAGACATGGGATTGTCACCATAGAATTAGTTGGTACTATGCCATCTTTCACTCTTTCACAAGTCAGTGA
TGGAACCTGCTTTATGACCAAGATTCATCCTCAAATAAGCCACATGTACCCTTCTGACAAAGCTGTGTAAAGTATTAGAATCTGATGCTC
TAGAAAGATCCTAGTTGCCTTTGTGTATATTTACTGCCTGCTTGAGTGTTTCTATGTGTGGGTTTTCCCTGTATCTTGTAGAAATGTTGG
GGTGTTTTCCTCTGCCATATGGCTCGTGGCCTGCGAGCCAACTATTTCAGCTGTATTTTACCTTCATTTTTGATGAGGTGATTTAAATTT
TGTTTCACTTTGTGTAGTGAATTCCACAGTAGTTTTCTGATTGTTGTTAAAAATGACTTAACATATTACACAGATATTCAATAAAAATGT

>21688_21688_7_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000543672_SYT1_chr12_79747282_ENST00000457153_length(amino acids)=164AA_BP=12
MADPKYADLPGIQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV

--------------------------------------------------------------
>21688_21688_8_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000543672_SYT1_chr12_79747282_ENST00000552744_length(transcript)=1811nt_BP=182nt
GCTACTGCTGTCGCGAGACTTCCTGCTCATCTGCCGCTCCCTTTGCCGCCGCCTTAGCCCGGGACCCGAACCCAGCCTCTCCCCTACCCG
AACACCGGCCCCGGCTCCACCGAGGCCCGGGTCCCCCAGCCCGTCTCGCCGCCGCCATGGCGGACCCTAAATACGCCGACCTTCCCGGCA
TTCAAGAGAAATTGGGTGATATCTGCTTCTCCCTTCGCTACGTACCTACTGCTGGTAAGCTGACTGTTGTCATTCTGGAGGCAAAGAACC
TGAAGAAGATGGATGTGGGTGGCTTATCCGATCCTTATGTGAAGATTCATCTGATGCAGAATGGTAAGAGGCTGAAGAAGAAAAAGACAA
CAATTAAAAAGAACACACTTAACCCCTACTACAATGAGTCATTCAGCTTTGAAGTACCTTTTGAACAAATCCAGAAAGTGCAGGTGGTGG
TAACTGTTTTGGACTATGACAAGATTGGCAAGAACGATGCCATCGGCAAAGTCTTTGTGGGCTACAACAGCACCGGCGCGGAGCTGCGAC
ACTGGTCAGACATGCTGGCCAACCCCAGGCGACCTATTGCCCAGTGGCACACCCTGCAGGTAGAGGAGGAAGTTGATGCCATGCTGGCCG
TCAAGAAGTAAAGGAAAGAAGAAGCCTTTCTGCATTTGCCCATATAGTGCTCTTTAGCCAGTATCTGTAAATACCTCAGTAATATGGGTC
CTTTCATTTTTCCAGCCATGCATTCCTAACACAATTCAGTGGTACTTGGAATCCTGTTTTAATTTGCACAAATTTAAATGTAGAGAGCCC
CTAAGTCCTTCATCATACCACTGCCCTCCAAATCTACTCTTCTTTTAAGCAATATGATGTGTAGATAGAGCATGAATGAAATTATTTATT
GTATCACACTGTTGTATATACCAGTATGCTAAAGATTTATTTCTAGTTTGTGTATTTGTATGTTGTAAGCGTTTCCTAATCTGTGTATAT
CTAGATGTTTTTAATAAGATGTTCTATTTTAAACTATGTAAATTGACTGAGATATAGGAGAGCTGATAATATATTATACGGTAAATATAG
TATCGTCTGCATTCCAGCAAAAATATCAACTCGTAAGGCACTAGTACAGTTAAACTGACATCTTAAAGGACAACTTAAACCTGAGCTTTC
TATTGAATCATTTGAGTACCAAGATAAACTTACACCACATACTTGGTGGGTGAATCCAATTTTGTAGAATTCCTACACAGGCAAAATAGC
ATGATCTGAGCAGCAGCATCCAGGCTGACCTCAAGGAAGCATAGCCACAAAACAGAATAGCACCTGTCTGTACATATTTACAAAGCTAAA
ATAATGGCTTCACTCTTATATTTGAGGAAGCAACTGAACAGGAGTCAATGATTTCATATTACTGCATATAGAATAACAACAAGGTGTTCC
GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCACATTTGTTTGGGGATGGGGGAGAAGAAGCTAAGGGGAGAAGTCAACATTTATG
AAATATTGCCTGACTATTTAAAAAGAAAAAAGTAGCTCTCCATTATCACCTTTATACAAAATGTACATCCTGTGAATTCTGTTCCAGATT
TCACACCTACAATAATTCCAAAAGGTTTGCACATTAGAGTTTGTAACAAAATATTTTATTATATAAAACCAGGTTAGAAGGAATGCAGGA
TATTTTTAACACAACAATCTGTGCTTATTACACAAAATTACTTTGTGGTAAACAGACAGTATTGTAATCCCATCAAAAGATGAAAGAAAA

>21688_21688_8_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000543672_SYT1_chr12_79747282_ENST00000552744_length(amino acids)=164AA_BP=12
MADPKYADLPGIQEKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEV

--------------------------------------------------------------
>21688_21688_9_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000548249_SYT1_chr12_79747282_ENST00000261205_length(transcript)=3645nt_BP=304nt
AATCCTAGGCGGCGTCCCCTGGCCATTACCTCATTCCCTGGCCTCGTTCTCCCCAATCCCGGCCTCTCCAGGGGTGTGGCAGCAGGGCTG
TTCTCGCGACTTTTGCTTTACCCTTCTGCTGTGCTACTGCTGTCGCGAGACTTCCTGCTCATCTGCCGCTCCCTTTGCCGCCGCCTTAGC
CCGGGACCCGAACCCAGCCTCTCCCCTACCCGAACACCGGCCCCGGCTCCACCGAGGCCCGGGTCCCCCAGCCCGTCTCGCCGCCGCCAT
GGCGGACCCTAAATACGCCGACCTTCCCGGCATTCAAGAGAAATTGGGTGATATCTGCTTCTCCCTTCGCTACGTACCTACTGCTGGTAA
GCTGACTGTTGTCATTCTGGAGGCAAAGAACCTGAAGAAGATGGATGTGGGTGGCTTATCCGATCCTTATGTGAAGATTCATCTGATGCA
GAATGGTAAGAGGCTGAAGAAGAAAAAGACAACAATTAAAAAGAACACACTTAACCCCTACTACAATGAGTCATTCAGCTTTGAAGTACC
TTTTGAACAAATCCAGAAAGTGCAGGTGGTGGTAACTGTTTTGGACTATGACAAGATTGGCAAGAACGATGCCATCGGCAAAGTCTTTGT
GGGCTACAACAGCACCGGCGCGGAGCTGCGACACTGGTCAGACATGCTGGCCAACCCCAGGCGACCTATTGCCCAGTGGCACACCCTGCA
GGTAGAGGAGGAAGTTGATGCCATGCTGGCCGTCAAGAAGTAAAGGAAAGAAGAAGCCTTTCTGCATTTGCCCATATAGTGCTCTTTAGC
CAGTATCTGTAAATACCTCAGTAATATGGGTCCTTTCATTTTTCCAGCCATGCATTCCTAACACAATTCAGTGGTACTTGGAATCCTGTT
TTAATTTGCACAAATTTAAATGTAGAGAGCCCCTAAGTCCTTCATCATACCACTGCCCTCCAAATCTACTCTTCTTTTAAGCAATATGAT
GTGTAGATAGAGCATGAATGAAATTATTTATTGTATCACACTGTTGTATATACCAGTATGCTAAAGATTTATTTCTAGTTTGTGTATTTG
TATGTTGTAAGCGTTTCCTAATCTGTGTATATCTAGATGTTTTTAATAAGATGTTCTATTTTAAACTATGTAAATTGACTGAGATATAGG
AGAGCTGATAATATATTATACGGTAAATATAGTATCGTCTGCATTCCAGCAAAAATATCAACTCGTAAGGCACTAGTACAGTTAAACTGA
CATCTTAAAGGACAACTTAAACCTGAGCTTTCTATTGAATCATTTGAGTACCAAGATAAACTTACACCACATACTTGGTGGGTGAATCCA
ATTTTGTAGAATTCCTACACAGGCAAAATAGCATGATCTGAGCAGCAGCATCCAGGCTGACCTCAAGGAAGCATAGCCACAAAACAGAAT
AGCACCTGTCTGTACATATTTACAAAGCTAAAATAATGGCTTCACTCTTATATTTGAGGAAGCAACTGAACAGGAGTCAATGATTTCATA
TTACTGCATATAGAATAACAACAAGGTGTTCCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCACATTTGTTTGGGGATGGGGGA
GAAGAAGCTAAGGGGAGAAGTCAACATTTATGAAATATTGCCTGACTATTTAAAAAGAAAAAAGTAGCTCTCCATTATCACCTTTATACA
AAATGTACATCCTGTGAATTCTGTTCCAGATTTCACACCTACAATAATTCCAAAAGGTTTGCACATTAGAGTTTGTAACAAAATATTTTA
TTATATAAAACCAGGTTAGAAGGAATGCAGGATATTTTTAACACAACAATCTGTGCTTATTACACAAAATTACTTTGTGGTAAACAGACA
GTATTGTAATCCCATCAAAAGATGAAAGAAAAACAAAAACAAAAACCAACAACAATTAGCCATAGTTCTGAATGCACTTCAATTAAGCCA
AAACAGACAGCTAGTGATCTTTTTATATGCTCTTTTTACTTAAGTTTTAATTTGTCCTTTAAAAAAAGGTGAAACAAACCAAGAACAAGT
TCTAGAAAACTGAAGCAACCTCTTATGTATACTAGATGCTTGATTTAGGAGGAGTTTTTAAACGTTTTCAATGTTATTATGTAGTAAATG
ACACTATTATGAAGCTACTAGTCATTCCATAAGAGTCTTAAAGGACTGCTCTGTGTAACACTGTGACTGCCGTGTGTGCTTAGACCCGTA
GTTTCCTCAGTGGATAGCACTCAATTTATTCCGTAGTGATATTGTAACAATACTGCCATTCCCTTCTACTGCACTGCCCAAGGTGTGTGT
AGCACAAACAGTTCTCATTACAAAGGACCAATTCAGAACTGAAAAGCTATGCATAGGACAAGGAAGATACATAGAATGGGGTGGAACACA
GCATTTTGTCAAGCACTGTGCAATATTCCATATTTTTCCCCACTATGGTAGACAACCATTTCGTGGAAGGGCAGCCTATTATCCCACACT
GCATCTAGCCTTTTGTCCCATTCACTTCTGTGATCCATTTTAATTTCCAGGCCACAAGACAGTAGTGATGCTCTGAAATGAAAGTTTGTC
TTCACAAATATCAAAACAAAATGGAGGAAAACTAAGCATTGGCCTCATGTTCAGTCTTCAGGATATCACACCACGTCTTTTCAAAAACTA
AAGAGAATTCAAAAAGGGCTGATGGTAGGCTTTGAACATGGGGTTGGCTGTTTCCCAGTAAAACTGGAATTCCTGTCGTTACTGTTTCCT
TATCAAAGAAGGGGCAAGCTCTTTTGCCTTTTAGGCCAGACATAGCAAACGCTTTATAATTGGCATAGACATAAAGGATAAAAGGAAAAT
AACCGTCTGCCGATGGTCCGTACTTCTTAAAAAACATAGGTAATAGAAAATATACACAAGTCAGAATGTGAAATTAAATAATGGTTTGAA
CAGAAAATTCAAACAAGACTCTTTCCAATTTAAAGGGCCAAACCCTACCAAAGAGAGGGAGTTGACTGGCTTTTAAAAAGTATTTAAATA
CCACAAATGACATTTAATTTCACTGTATTCAGCTTTAAGTTGTTCACAATGAAACCACACTTTCAAACAAGCAGGTTCAAGCTGCTGAAT
AGACATTATTTCTTGCATTAAAATACCACTAATGCATTCTCTTGCAACACTGCCAGACATGGGATTGTCACCATAGAATTAGTTGGTACT
ATGCCATCTTTCACTCTTTCACAAGTCAGTGATGGAACCTGCTTTATGACCAAGATTCATCCTCAAATAAGCCACATGTACCCTTCTGAC
AAAGCTGTGTAAAGTATTAGAATCTGATGCTCTAGAAAGATCCTAGTTGCCTTTGTGTATATTTACTGCCTGCTTGAGTGTTTCTATGTG
TGGGTTTTCCCTGTATCTTGTAGAAATGTTGGGGTGTTTTCCTCTGCCATATGGCTCGTGGCCTGCGAGCCAACTATTTCAGCTGTATTT
TACCTTCATTTTTGATGAGGTGATTTAAATTTTGTTTCACTTTGTGTAGTGAATTCCACAGTAGTTTTCTGATTGTTGTTAAAAATGACT

>21688_21688_9_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000548249_SYT1_chr12_79747282_ENST00000261205_length(amino acids)=241AA_BP=89
MASFSPIPASPGVWQQGCSRDFCFTLLLCYCCRETSCSSAAPFAAALARDPNPASPLPEHRPRLHRGPGPPARLAAAMADPKYADLPGIQ
EKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVT

--------------------------------------------------------------
>21688_21688_10_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000548249_SYT1_chr12_79747282_ENST00000393240_length(transcript)=1918nt_BP=304nt
AATCCTAGGCGGCGTCCCCTGGCCATTACCTCATTCCCTGGCCTCGTTCTCCCCAATCCCGGCCTCTCCAGGGGTGTGGCAGCAGGGCTG
TTCTCGCGACTTTTGCTTTACCCTTCTGCTGTGCTACTGCTGTCGCGAGACTTCCTGCTCATCTGCCGCTCCCTTTGCCGCCGCCTTAGC
CCGGGACCCGAACCCAGCCTCTCCCCTACCCGAACACCGGCCCCGGCTCCACCGAGGCCCGGGTCCCCCAGCCCGTCTCGCCGCCGCCAT
GGCGGACCCTAAATACGCCGACCTTCCCGGCATTCAAGAGAAATTGGGTGATATCTGCTTCTCCCTTCGCTACGTACCTACTGCTGGTAA
GCTGACTGTTGTCATTCTGGAGGCAAAGAACCTGAAGAAGATGGATGTGGGTGGCTTATCCGATCCTTATGTGAAGATTCATCTGATGCA
GAATGGTAAGAGGCTGAAGAAGAAAAAGACAACAATTAAAAAGAACACACTTAACCCCTACTACAATGAGTCATTCAGCTTTGAAGTACC
TTTTGAACAAATCCAGAAAGTGCAGGTGGTGGTAACTGTTTTGGACTATGACAAGATTGGCAAGAACGATGCCATCGGCAAAGTCTTTGT
GGGCTACAACAGCACCGGCGCGGAGCTGCGACACTGGTCAGACATGCTGGCCAACCCCAGGCGACCTATTGCCCAGTGGCACACCCTGCA
GGTAGAGGAGGAAGTTGATGCCATGCTGGCCGTCAAGAAGTAAAGGAAAGAAGAAGCCTTTCTGCATTTGCCCATATAGTGCTCTTTAGC
CAGTATCTGTAAATACCTCAGTAATATGGGTCCTTTCATTTTTCCAGCCATGCATTCCTAACACAATTCAGTGGTACTTGGAATCCTGTT
TTAATTTGCACAAATTTAAATGTAGAGAGCCCCTAAGTCCTTCATCATACCACTGCCCTCCAAATCTACTCTTCTTTTAAGCAATATGAT
GTGTAGATAGAGCATGAATGAAATTATTTATTGTATCACACTGTTGTATATACCAGTATGCTAAAGATTTATTTCTAGTTTGTGTATTTG
TATGTTGTAAGCGTTTCCTAATCTGTGTATATCTAGATGTTTTTAATAAGATGTTCTATTTTAAACTATGTAAATTGACTGAGATATAGG
AGAGCTGATAATATATTATACGGTAAATATAGTATCGTCTGCATTCCAGCAAAAATATCAACTCGTAAGGCACTAGTACAGTTAAACTGA
CATCTTAAAGGACAACTTAAACCTGAGCTTTCTATTGAATCATTTGAGTACCAAGATAAACTTACACCACATACTTGGTGGGTGAATCCA
ATTTTGTAGAATTCCTACACAGGCAAAATAGCATGATCTGAGCAGCAGCATCCAGGCTGACCTCAAGGAAGCATAGCCACAAAACAGAAT
AGCACCTGTCTGTACATATTTACAAAGCTAAAATAATGGCTTCACTCTTATATTTGAGGAAGCAACTGAACAGGAGTCAATGATTTCATA
TTACTGCATATAGAATAACAACAAGGTGTTCCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCACATTTGTTTGGGGATGGGGGA
GAAGAAGCTAAGGGGAGAAGTCAACATTTATGAAATATTGCCTGACTATTTAAAAAGAAAAAAGTAGCTCTCCATTATCACCTTTATACA
AAATGTACATCCTGTGAATTCTGTTCCAGATTTCACACCTACAATAATTCCAAAAGGTTTGCACATTAGAGTTTGTAACAAAATATTTTA
TTATATAAAACCAGGTTAGAAGGAATGCAGGATATTTTTAACACAACAATCTGTGCTTATTACACAAAATTACTTTGTGGTAAACAGACA

>21688_21688_10_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000548249_SYT1_chr12_79747282_ENST00000393240_length(amino acids)=241AA_BP=89
MASFSPIPASPGVWQQGCSRDFCFTLLLCYCCRETSCSSAAPFAAALARDPNPASPLPEHRPRLHRGPGPPARLAAAMADPKYADLPGIQ
EKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVT

--------------------------------------------------------------
>21688_21688_11_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000548249_SYT1_chr12_79747282_ENST00000457153_length(transcript)=3647nt_BP=304nt
AATCCTAGGCGGCGTCCCCTGGCCATTACCTCATTCCCTGGCCTCGTTCTCCCCAATCCCGGCCTCTCCAGGGGTGTGGCAGCAGGGCTG
TTCTCGCGACTTTTGCTTTACCCTTCTGCTGTGCTACTGCTGTCGCGAGACTTCCTGCTCATCTGCCGCTCCCTTTGCCGCCGCCTTAGC
CCGGGACCCGAACCCAGCCTCTCCCCTACCCGAACACCGGCCCCGGCTCCACCGAGGCCCGGGTCCCCCAGCCCGTCTCGCCGCCGCCAT
GGCGGACCCTAAATACGCCGACCTTCCCGGCATTCAAGAGAAATTGGGTGATATCTGCTTCTCCCTTCGCTACGTACCTACTGCTGGTAA
GCTGACTGTTGTCATTCTGGAGGCAAAGAACCTGAAGAAGATGGATGTGGGTGGCTTATCCGATCCTTATGTGAAGATTCATCTGATGCA
GAATGGTAAGAGGCTGAAGAAGAAAAAGACAACAATTAAAAAGAACACACTTAACCCCTACTACAATGAGTCATTCAGCTTTGAAGTACC
TTTTGAACAAATCCAGAAAGTGCAGGTGGTGGTAACTGTTTTGGACTATGACAAGATTGGCAAGAACGATGCCATCGGCAAAGTCTTTGT
GGGCTACAACAGCACCGGCGCGGAGCTGCGACACTGGTCAGACATGCTGGCCAACCCCAGGCGACCTATTGCCCAGTGGCACACCCTGCA
GGTAGAGGAGGAAGTTGATGCCATGCTGGCCGTCAAGAAGTAAAGGAAAGAAGAAGCCTTTCTGCATTTGCCCATATAGTGCTCTTTAGC
CAGTATCTGTAAATACCTCAGTAATATGGGTCCTTTCATTTTTCCAGCCATGCATTCCTAACACAATTCAGTGGTACTTGGAATCCTGTT
TTAATTTGCACAAATTTAAATGTAGAGAGCCCCTAAGTCCTTCATCATACCACTGCCCTCCAAATCTACTCTTCTTTTAAGCAATATGAT
GTGTAGATAGAGCATGAATGAAATTATTTATTGTATCACACTGTTGTATATACCAGTATGCTAAAGATTTATTTCTAGTTTGTGTATTTG
TATGTTGTAAGCGTTTCCTAATCTGTGTATATCTAGATGTTTTTAATAAGATGTTCTATTTTAAACTATGTAAATTGACTGAGATATAGG
AGAGCTGATAATATATTATACGGTAAATATAGTATCGTCTGCATTCCAGCAAAAATATCAACTCGTAAGGCACTAGTACAGTTAAACTGA
CATCTTAAAGGACAACTTAAACCTGAGCTTTCTATTGAATCATTTGAGTACCAAGATAAACTTACACCACATACTTGGTGGGTGAATCCA
ATTTTGTAGAATTCCTACACAGGCAAAATAGCATGATCTGAGCAGCAGCATCCAGGCTGACCTCAAGGAAGCATAGCCACAAAACAGAAT
AGCACCTGTCTGTACATATTTACAAAGCTAAAATAATGGCTTCACTCTTATATTTGAGGAAGCAACTGAACAGGAGTCAATGATTTCATA
TTACTGCATATAGAATAACAACAAGGTGTTCCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCACATTTGTTTGGGGATGGGGGA
GAAGAAGCTAAGGGGAGAAGTCAACATTTATGAAATATTGCCTGACTATTTAAAAAGAAAAAAGTAGCTCTCCATTATCACCTTTATACA
AAATGTACATCCTGTGAATTCTGTTCCAGATTTCACACCTACAATAATTCCAAAAGGTTTGCACATTAGAGTTTGTAACAAAATATTTTA
TTATATAAAACCAGGTTAGAAGGAATGCAGGATATTTTTAACACAACAATCTGTGCTTATTACACAAAATTACTTTGTGGTAAACAGACA
GTATTGTAATCCCATCAAAAGATGAAAGAAAAACAAAAACAAAAACCAACAACAATTAGCCATAGTTCTGAATGCACTTCAATTAAGCCA
AAACAGACAGCTAGTGATCTTTTTATATGCTCTTTTTACTTAAGTTTTAATTTGTCCTTTAAAAAAAGGTGAAACAAACCAAGAACAAGT
TCTAGAAAACTGAAGCAACCTCTTATGTATACTAGATGCTTGATTTAGGAGGAGTTTTTAAACGTTTTCAATGTTATTATGTAGTAAATG
ACACTATTATGAAGCTACTAGTCATTCCATAAGAGTCTTAAAGGACTGCTCTGTGTAACACTGTGACTGCCGTGTGTGCTTAGACCCGTA
GTTTCCTCAGTGGATAGCACTCAATTTATTCCGTAGTGATATTGTAACAATACTGCCATTCCCTTCTACTGCACTGCCCAAGGTGTGTGT
AGCACAAACAGTTCTCATTACAAAGGACCAATTCAGAACTGAAAAGCTATGCATAGGACAAGGAAGATACATAGAATGGGGTGGAACACA
GCATTTTGTCAAGCACTGTGCAATATTCCATATTTTTCCCCACTATGGTAGACAACCATTTCGTGGAAGGGCAGCCTATTATCCCACACT
GCATCTAGCCTTTTGTCCCATTCACTTCTGTGATCCATTTTAATTTCCAGGCCACAAGACAGTAGTGATGCTCTGAAATGAAAGTTTGTC
TTCACAAATATCAAAACAAAATGGAGGAAAACTAAGCATTGGCCTCATGTTCAGTCTTCAGGATATCACACCACGTCTTTTCAAAAACTA
AAGAGAATTCAAAAAGGGCTGATGGTAGGCTTTGAACATGGGGTTGGCTGTTTCCCAGTAAAACTGGAATTCCTGTCGTTACTGTTTCCT
TATCAAAGAAGGGGCAAGCTCTTTTGCCTTTTAGGCCAGACATAGCAAACGCTTTATAATTGGCATAGACATAAAGGATAAAAGGAAAAT
AACCGTCTGCCGATGGTCCGTACTTCTTAAAAAACATAGGTAATAGAAAATATACACAAGTCAGAATGTGAAATTAAATAATGGTTTGAA
CAGAAAATTCAAACAAGACTCTTTCCAATTTAAAGGGCCAAACCCTACCAAAGAGAGGGAGTTGACTGGCTTTTAAAAAGTATTTAAATA
CCACAAATGACATTTAATTTCACTGTATTCAGCTTTAAGTTGTTCACAATGAAACCACACTTTCAAACAAGCAGGTTCAAGCTGCTGAAT
AGACATTATTTCTTGCATTAAAATACCACTAATGCATTCTCTTGCAACACTGCCAGACATGGGATTGTCACCATAGAATTAGTTGGTACT
ATGCCATCTTTCACTCTTTCACAAGTCAGTGATGGAACCTGCTTTATGACCAAGATTCATCCTCAAATAAGCCACATGTACCCTTCTGAC
AAAGCTGTGTAAAGTATTAGAATCTGATGCTCTAGAAAGATCCTAGTTGCCTTTGTGTATATTTACTGCCTGCTTGAGTGTTTCTATGTG
TGGGTTTTCCCTGTATCTTGTAGAAATGTTGGGGTGTTTTCCTCTGCCATATGGCTCGTGGCCTGCGAGCCAACTATTTCAGCTGTATTT
TACCTTCATTTTTGATGAGGTGATTTAAATTTTGTTTCACTTTGTGTAGTGAATTCCACAGTAGTTTTCTGATTGTTGTTAAAAATGACT

>21688_21688_11_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000548249_SYT1_chr12_79747282_ENST00000457153_length(amino acids)=241AA_BP=89
MASFSPIPASPGVWQQGCSRDFCFTLLLCYCCRETSCSSAAPFAAALARDPNPASPLPEHRPRLHRGPGPPARLAAAMADPKYADLPGIQ
EKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVT

--------------------------------------------------------------
>21688_21688_12_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000548249_SYT1_chr12_79747282_ENST00000552744_length(transcript)=1933nt_BP=304nt
AATCCTAGGCGGCGTCCCCTGGCCATTACCTCATTCCCTGGCCTCGTTCTCCCCAATCCCGGCCTCTCCAGGGGTGTGGCAGCAGGGCTG
TTCTCGCGACTTTTGCTTTACCCTTCTGCTGTGCTACTGCTGTCGCGAGACTTCCTGCTCATCTGCCGCTCCCTTTGCCGCCGCCTTAGC
CCGGGACCCGAACCCAGCCTCTCCCCTACCCGAACACCGGCCCCGGCTCCACCGAGGCCCGGGTCCCCCAGCCCGTCTCGCCGCCGCCAT
GGCGGACCCTAAATACGCCGACCTTCCCGGCATTCAAGAGAAATTGGGTGATATCTGCTTCTCCCTTCGCTACGTACCTACTGCTGGTAA
GCTGACTGTTGTCATTCTGGAGGCAAAGAACCTGAAGAAGATGGATGTGGGTGGCTTATCCGATCCTTATGTGAAGATTCATCTGATGCA
GAATGGTAAGAGGCTGAAGAAGAAAAAGACAACAATTAAAAAGAACACACTTAACCCCTACTACAATGAGTCATTCAGCTTTGAAGTACC
TTTTGAACAAATCCAGAAAGTGCAGGTGGTGGTAACTGTTTTGGACTATGACAAGATTGGCAAGAACGATGCCATCGGCAAAGTCTTTGT
GGGCTACAACAGCACCGGCGCGGAGCTGCGACACTGGTCAGACATGCTGGCCAACCCCAGGCGACCTATTGCCCAGTGGCACACCCTGCA
GGTAGAGGAGGAAGTTGATGCCATGCTGGCCGTCAAGAAGTAAAGGAAAGAAGAAGCCTTTCTGCATTTGCCCATATAGTGCTCTTTAGC
CAGTATCTGTAAATACCTCAGTAATATGGGTCCTTTCATTTTTCCAGCCATGCATTCCTAACACAATTCAGTGGTACTTGGAATCCTGTT
TTAATTTGCACAAATTTAAATGTAGAGAGCCCCTAAGTCCTTCATCATACCACTGCCCTCCAAATCTACTCTTCTTTTAAGCAATATGAT
GTGTAGATAGAGCATGAATGAAATTATTTATTGTATCACACTGTTGTATATACCAGTATGCTAAAGATTTATTTCTAGTTTGTGTATTTG
TATGTTGTAAGCGTTTCCTAATCTGTGTATATCTAGATGTTTTTAATAAGATGTTCTATTTTAAACTATGTAAATTGACTGAGATATAGG
AGAGCTGATAATATATTATACGGTAAATATAGTATCGTCTGCATTCCAGCAAAAATATCAACTCGTAAGGCACTAGTACAGTTAAACTGA
CATCTTAAAGGACAACTTAAACCTGAGCTTTCTATTGAATCATTTGAGTACCAAGATAAACTTACACCACATACTTGGTGGGTGAATCCA
ATTTTGTAGAATTCCTACACAGGCAAAATAGCATGATCTGAGCAGCAGCATCCAGGCTGACCTCAAGGAAGCATAGCCACAAAACAGAAT
AGCACCTGTCTGTACATATTTACAAAGCTAAAATAATGGCTTCACTCTTATATTTGAGGAAGCAACTGAACAGGAGTCAATGATTTCATA
TTACTGCATATAGAATAACAACAAGGTGTTCCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCACATTTGTTTGGGGATGGGGGA
GAAGAAGCTAAGGGGAGAAGTCAACATTTATGAAATATTGCCTGACTATTTAAAAAGAAAAAAGTAGCTCTCCATTATCACCTTTATACA
AAATGTACATCCTGTGAATTCTGTTCCAGATTTCACACCTACAATAATTCCAAAAGGTTTGCACATTAGAGTTTGTAACAAAATATTTTA
TTATATAAAACCAGGTTAGAAGGAATGCAGGATATTTTTAACACAACAATCTGTGCTTATTACACAAAATTACTTTGTGGTAAACAGACA

>21688_21688_12_DCTN2-SYT1_DCTN2_chr12_57940811_ENST00000548249_SYT1_chr12_79747282_ENST00000552744_length(amino acids)=241AA_BP=89
MASFSPIPASPGVWQQGCSRDFCFTLLLCYCCRETSCSSAAPFAAALARDPNPASPLPEHRPRLHRGPGPPARLAAAMADPKYADLPGIQ
EKLGDICFSLRYVPTAGKLTVVILEAKNLKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVVT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for DCTN2-SYT1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DCTN2-SYT1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DCTN2-SYT1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource