|
||||||
|
 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:DCUN1D1-CCDC50 (FusionGDB2 ID:21704) |
Fusion Gene Summary for DCUN1D1-CCDC50 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: DCUN1D1-CCDC50 | Fusion gene ID: 21704 | Hgene | Tgene | Gene symbol | DCUN1D1 | CCDC50 | Gene ID | 54165 | 152137 |
| Gene name | defective in cullin neddylation 1 domain containing 1 | coiled-coil domain containing 50 | |
| Synonyms | DCNL1|DCUN1L1|RP42|SCCRO|SCRO|Tes3 | C3orf6|DFNA44|YMER | |
| Cytomap | 3q26.33 | 3q28 | |
| Type of gene | protein-coding | protein-coding | |
| Description | DCN1-like protein 1DCN1, defective in cullin neddylation 1, domain containing 1DCUN1 domain-containing protein 1RP42 homologdefective in cullin neddylation protein 1-like protein 1squamous cell carcinoma-related oncogene | coiled-coil domain-containing protein 50protein Ymer | |
| Modification date | 20200327 | 20200313 | |
| UniProtAcc | Q96GG9 | Q8IVM0 | |
| Ensembl transtripts involved in fusion gene | ENST00000292782, ENST00000469954, | ENST00000392455, ENST00000392456, | |
| Fusion gene scores | * DoF score | 6 X 6 X 5=180 | 8 X 5 X 7=280 |
| # samples | 6 | 8 | |
| ** MAII score | log2(6/180*10)=-1.58496250072116 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/280*10)=-1.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: DCUN1D1 [Title/Abstract] AND CCDC50 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | DCUN1D1(182679014)-CCDC50(191074877), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across DCUN1D1 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
| Fusion gene breakpoints across CCDC50 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
 |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | BRCA | TCGA-AO-A0JM-01A | DCUN1D1 | chr3 | 182679014 | - | CCDC50 | chr3 | 191074877 | + |
Top |
Fusion Gene ORF analysis for DCUN1D1-CCDC50 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| In-frame | ENST00000292782 | ENST00000392455 | DCUN1D1 | chr3 | 182679014 | - | CCDC50 | chr3 | 191074877 | + |
| In-frame | ENST00000292782 | ENST00000392456 | DCUN1D1 | chr3 | 182679014 | - | CCDC50 | chr3 | 191074877 | + |
| In-frame | ENST00000469954 | ENST00000392455 | DCUN1D1 | chr3 | 182679014 | - | CCDC50 | chr3 | 191074877 | + |
| In-frame | ENST00000469954 | ENST00000392456 | DCUN1D1 | chr3 | 182679014 | - | CCDC50 | chr3 | 191074877 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000292782 | DCUN1D1 | chr3 | 182679014 | - | ENST00000392455 | CCDC50 | chr3 | 191074877 | + | 8456 | 674 | 139 | 1545 | 468 |
| ENST00000292782 | DCUN1D1 | chr3 | 182679014 | - | ENST00000392456 | CCDC50 | chr3 | 191074877 | + | 2489 | 674 | 139 | 2073 | 644 |
| ENST00000469954 | DCUN1D1 | chr3 | 182679014 | - | ENST00000392455 | CCDC50 | chr3 | 191074877 | + | 8432 | 650 | 124 | 1521 | 465 |
| ENST00000469954 | DCUN1D1 | chr3 | 182679014 | - | ENST00000392456 | CCDC50 | chr3 | 191074877 | + | 2465 | 650 | 124 | 2049 | 641 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000292782 | ENST00000392455 | DCUN1D1 | chr3 | 182679014 | - | CCDC50 | chr3 | 191074877 | + | 0.000188433 | 0.9998116 |
| ENST00000292782 | ENST00000392456 | DCUN1D1 | chr3 | 182679014 | - | CCDC50 | chr3 | 191074877 | + | 0.005674375 | 0.9943256 |
| ENST00000469954 | ENST00000392455 | DCUN1D1 | chr3 | 182679014 | - | CCDC50 | chr3 | 191074877 | + | 0.000206652 | 0.99979335 |
| ENST00000469954 | ENST00000392456 | DCUN1D1 | chr3 | 182679014 | - | CCDC50 | chr3 | 191074877 | + | 0.006662843 | 0.99333715 |
Top |
Fusion Genomic Features for DCUN1D1-CCDC50 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| DCUN1D1 | chr3 | 182679013 | - | CCDC50 | chr3 | 191074876 | + | 7.14E-06 | 0.99999285 |
| DCUN1D1 | chr3 | 182679013 | - | CCDC50 | chr3 | 191074876 | + | 7.14E-06 | 0.99999285 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
 |
Top |
Fusion Protein Features for DCUN1D1-CCDC50 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:182679014/chr3:191074877) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
 |
| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| DCUN1D1 | CCDC50 |
| FUNCTION: Part of an E3 ubiquitin ligase complex for neddylation (PubMed:18826954). Promotes neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes (PubMed:26906416, PubMed:23201271, PubMed:19617556, PubMed:23401859). Acts by binding to cullin-RBX1 complexes in the cytoplasm and promoting their nuclear translocation, enhancing recruitment of E2-NEDD8 (UBE2M-NEDD8) thioester to the complex, and optimizing the orientation of proteins in the complex to allow efficient transfer of NEDD8 from the E2 to the cullin substrates. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity (PubMed:25349211, PubMed:28581483). Acts also as an oncogene facilitating malignant transformation and carcinogenic progression (By similarity). {ECO:0000250|UniProtKB:Q9QZ73, ECO:0000269|PubMed:18826954, ECO:0000269|PubMed:19617556, ECO:0000269|PubMed:23201271, ECO:0000269|PubMed:23401859, ECO:0000269|PubMed:25349211, ECO:0000269|PubMed:26906416, ECO:0000269|PubMed:28581483}. | FUNCTION: Involved in EGFR signaling. {ECO:0000269|PubMed:15314609}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | DCUN1D1 | chr3:182679014 | chr3:191074877 | ENST00000292782 | - | 4 | 7 | 8_45 | 173 | 260.0 | Domain | Note=UBA-like |
| Tgene | CCDC50 | chr3:182679014 | chr3:191074877 | ENST00000392455 | 0 | 11 | 63_130 | 16 | 307.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | CCDC50 | chr3:182679014 | chr3:191074877 | ENST00000392456 | 0 | 12 | 63_130 | 16 | 483.0 | Coiled coil | Ontology_term=ECO:0000255 | |
| Tgene | CCDC50 | chr3:182679014 | chr3:191074877 | ENST00000392455 | 0 | 11 | 214_250 | 16 | 307.0 | Compositional bias | Note=Lys-rich | |
| Tgene | CCDC50 | chr3:182679014 | chr3:191074877 | ENST00000392455 | 0 | 11 | 266_269 | 16 | 307.0 | Compositional bias | Note=Poly-Pro | |
| Tgene | CCDC50 | chr3:182679014 | chr3:191074877 | ENST00000392456 | 0 | 12 | 214_250 | 16 | 483.0 | Compositional bias | Note=Lys-rich | |
| Tgene | CCDC50 | chr3:182679014 | chr3:191074877 | ENST00000392456 | 0 | 12 | 266_269 | 16 | 483.0 | Compositional bias | Note=Poly-Pro |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | DCUN1D1 | chr3:182679014 | chr3:191074877 | ENST00000292782 | - | 4 | 7 | 60_248 | 173 | 260.0 | Domain | DCUN1 |
Top |
Fusion Gene Sequence for DCUN1D1-CCDC50 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >21704_21704_1_DCUN1D1-CCDC50_DCUN1D1_chr3_182679014_ENST00000292782_CCDC50_chr3_191074877_ENST00000392455_length(transcript)=8456nt_BP=674nt CGAGGTCCGGGGCTGCCTCCTCGGGCCGCGCCGGGCCGCCCCGCACTGCGCATGAGCGGGAGCCGGGCAAGCCCGTGAGAGGAGCCGCCG CCGCCGCCGCCGTCCATTCGCTGCGGAGCCGGAGGAGGAGGGGAGAGGCCTGGAGGACACCAACATGAACAAGTTGAAATCATCGCAGAA GGATAAAGTTCGTCAGTTTATGATCTTCACACAATCTAGTGAAAAAACAGCAGTAAGTTGTCTTTCTCAAAATGACTGGAAGTTAGATGT TGCAACAGATAATTTTTTCCAAAATCCTGAACTTTATATACGAGAGAGTGTAAAAGGATCATTGGACAGGAAGAAGTTAGAACAGCTGTA CAATAGATACAAAGACCCTCAAGATGAGAATAAAATTGGAATAGATGGCATACAGCAGTTCTGTGATGACCTGGCACTCGATCCAGCCAG CATTAGTGTGTTGATTATTGCGTGGAAGTTCAGAGCAGCAACACAGTGCGAGTTCTCCAAACAGGAGTTCATGGATGGCATGACAGAATT AGGATGTGACAGCATAGAAAAACTAAAGGCCCAGATACCCAAGATGGAACAAGAATTGAAAGAACCAGGACGATTTAAGGATTTTTACCA GTTTACTTTTAATTTTGCAAAGAATCCAGGACAAAAAGGATTAGTATGCCGAGATTTTGCTGTCCTGGAGGACCACACCCTGGCTCACAG CCTGCAGGAACAAGAGATTGAGCATCATTTGGCATCGAACGTTCAGCGGAACCGTTTGGTCCAGCATGATCTCCAGGTGGCTAAGCAGCT CCAAGAGGAAGATCTGAAAGCGCAGGCCCAGCTCCAGAAGCGCTACAAAGACCTTGAACAACAAGACTGTGAAATTGCTCAGGAAATTCA GGAGAAGCTGGCTATTGAGGCAGAGAGACGACGCATTCAGGAGAAGAAGGATGAGGACATAGCTCGCCTTTTGCAAGAAAAGGAGTTACA GGAAGAGAAAAAGAGAAAGAAACACTTTCCAGAGTTCCCTGCAACCCGTGCTTATGCAGATAGTTACTATTATGAAGATGGAGGAATGAA GCCAAGAGTGATGAAAGAAGCTGTATCTACTCCATCACGAATGGCCCACAGGGATCAGGAATGGTATGATGCTGAAATTGCCAGAAAACT GCAAGAAGAAGAACTTTTGGCTACCCAGGTGGACATGAGAGCCGCTCAAGTAGCTCAAGATGAAGAAATCGCTCGACTTCTAATGGCTGA AGAAAAGAAAGCTTACAAAAAAGCCAAGGAGCGGGAGAAATCATCTTTGGACAAAAGAAAGCAAGACCCCGAGTGGAAGCCAAAAACAGC TAAAGCAGCAAATTCCAAGTCAAAAGAGAGTGATGAACCTCACCATTCTAAGAATGAAAGGCCAGCACGGCCACCACCACCTATCATGAC AGATGGTGAAGATGCGGATTACACTCATTTTACAAACCAGCAGAGTTCCACACGGCATTTCTCAAAATCAGAGTCCTCTCATAAAGGTTT TCATTACAAACATTAAAAACCTAGGAATCTGCCTTGAAAATGGACTCACTATAGCAAATATTACTGGGTGATACAGAATGAATTCTACAC TTACTTTTTTTCTCCTGTGTTTGCATTCCTGGGATTTATCCTCAAGTGCATTTCTGACCATAAGTAATTTTAATTCATTTCAAATGTTTT GGTTATTCATGATCACTTGGGCAGTATAAGAAAATGTAGCTTCTGAATATTGGCCACCTCTATGCTGCATATACTTCTTGGGATATAGTA TCTAAGACCTTTGTAAACTGCCATTTTGTTAGGTATGGAGTTTGGTATCTAGGGAGTAGGCCTTATTTAGCAATTCAAATTTTATGGAGA TGAATGATCAAAGTGAAACAATGTTTGGATGCAACGCAGAATAAAAGAATATAAGAAATAGCTTTTTGTTGCATTAATGTATGATATTTT GAAGGACAGAGCCTTTGCTTTTTGTATTCTTTAAGAAAAGCACAACCATAAAGTATTTTAAAAAAAGAAACACTTGGAGCAATTGAAATA TGTTATTCTGACTAGATGGACTGTAGAGGTTTTGCATTTCTCAGCCCTCCTGGGGAGATTGGCCTAGATAGCATTCTTTAACACTTCCTC TGCTTTTGCCTCAGTAGCAAGGCTTTCCTAAGCTCCTGGGCAATGGAACATTTATTAGTATTTATTGACAAAAATTTAGTTCTCTGAAAT TTTAACTCATATATATGAAAAACTTTGTATTCCATCTCTTCTTTTTCATTTACTTGTAGAGCCAAGGAAATGGAATTGAAAGATGATTGC ATAAGTAATGATGCCATCCTTCTCTCTGGCTGTAGACTGAGGCTTTTCTCTTGCTTCAAGTCAGAGCAGTATTTGTTGATAACCTCTCAA TAATGTTTGGTTTACATGCCAGTAATTAAATTAATTCAACATGAAGTTGAATTTGATGAAGTGGTCATCTATCCAAGTATTTGGTTTTTG TTTTGTTTTGTTTTGTTTTTTGAGTTGGAGTCTCGCCCTGTCACACAGGCTGGAGTGCAGTGGTGCAATCTTGGCTCACTGCAACCTCCG CCACCTGGGCTGGAGCAATTCCCCTGCCTCAGCCTCCCAAGTAGCTGGAATTACAGGCATGTGTCACCACACCCGGCTAATTTTTGTATT TTTAGTAAAGAGCGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACCCCTGACCTCAAGTGATCCACCTGCCTTGGCCTCCCAAGGTGC TGGGATTACAGGCTTAAGCCACCATGTCCAGCCAGCCAAGTATTTGGTTTTAAACATTTGTATTCCTTTGTGCAAGGGATTGTATTCCTC TGTACAAGACCTTTAAGCACCTCTTCAAGAAATTTAGTCTTTGTGTAGCTGCTAACCTTACTGCAATATTTATTTTCCCTTATTTTCCCA TACTACTTAGTTGACAAATGGCAATCAAGCTCACTTGTTCTCCCTCTCTCTGTCTCCCCCCCATGTACACATATATATATCCCTTCAGCT TGACTTGCTATTATTTTTCATTGTATAAATATGAAATTCTTGGCATTTCAATATGGCATTTGTTTAGGGAAAAAATATGTAGGTCACTAG AGAAAAATGTTAATTTTTTTCCCACTGTGAATTGCCTTCTGTTTGCCTTATCTTTTCAGATAGTCTTTAAAGTTGGGCAATATTCAGGCA GCTATTTAGAACAGTTTCTCAGAGTGGATTTGGGTCTCTCATTTGAGAAAGATTTGTAGTTTCAATGAAGTTTGTATATTATAGGAATTT AAGTAAAATCATCTGAGTTAAGTTTTGGGCAAATGTTAATCAGAAAGATAATCTACATCCCTACTTTATGTAGTCATTTTGGAGAAATGG AGGAAAAGGAAAATAACAGGACTTTTTATAGCTGTGATAAAATGGGTAAAGAAAAACCTCCATTTAAATAAGGAAGGGGAGACAAAATGG AAGGTCCTGGCCTTAAGTCAAATTCCAGATAGTGCTTTCAATATCCAAAGCTTAGGCCTTGTTTACTTATAGTAATGCTATATTTTTCTT TATCTGCCCTGTGATTTCGCTTCGTGTCCTTCAAAGTTTTTTTATTGTAATTTTAAAGGAAAAAAACAATGTATTTTTATTTGATAACTA GGCAAAATCATTTGCCATTTTTTATTTCATAAATATTTATTTTTCTATCTCATACAATGATCAGTTTTACTTTAAAAATTCTGCATTTCT CTTGCCTCTCATGTACTTCATCCAGTTATTTATTATTGTAAAATGTTAACTGGAGATACTGCATTCAAAAAAAAGTCGGACCACTTAACA CTTACCAGGAATGTTAGTGTTTCAGCTGTTTTAGTAAGTGACCAAGTAAGCTATCACCTTGTGATAGCTAATTCAACATCTTTATTGAAA ATTTGTTACTTTTTTTAAAGGTTTTTAAAAGATTACAATTTTAAAATATTTTATGTTTATTTTATTTTTGTGTAAAGCAAACACTTTTAA AATAATATCAGAGTAATTATTACCCTATGAATAAGGAGATAGAAATGAAATTCAGCCAGTTAAATCCTCATACTCTTTCTCATTCAAATA ATATAATAATGTTTGAGACTATAGAAGCAACTCAACTGTATTTTAATGAACTGCCAGACACTTTTCACTGTGTTCTCTGCTTTTTACTTT GTCATTTTTATATAAATGTGAAAGCATTTTGTTGTTGTTGTTGTTGTTCCTGCTGCTAGAACACATGCAGTTTAATTTTTAGGCCCACAG TGTATTATGCTTTAATGTTGTGATGTAAACTAATACTTCTGGCCTGGGAAAACCTTTCTGTTTCTGTATCTTTGTCCTTTGGAGGCCAGG CCTCATTAACACCAGTATTGTTGAATAAGCACAATATATGACGGAGCCTTATCATAAGGCTGCTTGACATAGACACCCACTCTCCTCCAC ATTTTATAAATCATTGTTTGGAAGTAAAGTTAGATAAGAGTCAAATTAAATGTTTTGACTTGAAAAATATTTGACTTTTGCGTTCAAACC ACTGTTAGACGTAAGTATTTTATTAGACATAAGTATTTTATTTTGGGACTAGACAGTTGCTTTACATGTATTTAAGGGAACATTGTGATT TTCAGAAAGTGGCTTTACATACTATTGAATTGCTATTTCCCAAGTTACTTTACAACCAGCAGCAGCATACCAATAAATTACAAAAGCAGA AAATGAAAATTAACCCTAGGTGTTCTGATGATAGAGAAATAGCTAAATTAGAAAAGAAAGATATGGATAGATGCTTTTAGGAGGAAAACC TTTTTAGAATGGCAATGACCACTTGGATCTAGGTCAACATATTCCAAAATGTGTGACCTTGGGCTTTGTGTTTACTGAACTCACTCTAGA AAATTCTGGACCTGATTCATTAACCCCGCTTTTCTTCTCTAATGTGTCCTGAAGCTGAGCTAGATGATGAGTAAATTCTTTGCTGACTGT TGCTCATCACTTTCTCTCAAAGTTAGAACTTTTCAGTATAAAAATAATTAGCTTTTAACTGATTATTAATTTTCTTTAATAGTTTCTGTC AAAACTTGTCTAAAATTTGTGTTGTGCCAAATTGGAAATACCCACTATAATATGGTGCATTCAGTTTACTCCACAAGTGGTTAACATTTT AAGTCCTAGATTTTTTATGTCTTGCCTTTGTATAAGCATCGCTTTGGGGAATACCAAGATGATTCATTATTCAGTGATTATTTTCTTGAA AGATAACTATGATGATTGGCTGTAAAATCTTCACCCTAATAAAGGAGTGAGATCTCTGTGTAAACAGCTTTCTGAAGGACTGATAATAGA ATAGAACTTGCAGCCAAAGGCTTTTTCCCTTTTGAGAAGACGGTATTTGTGTAAGGAGTGCTAAGGTAGACTTCATTGTACATAGAGTGC CATATTCTGTTGAAACGATCATAACAAAATCAAAACCTCATGCTTCAGCAAAAAGGAAAAAAGATTTTTAAATTACTTTGTCTATTACTT ACTGCTCATAGAGAAGTGACTATATAAAATGGTCCAATTTTCTCATTTCTGGTGGTGCCTGTGAGTCTTAAAGCCATATCTGCTTATCTT ACTGTTGATAGAATACTTTTTTTCTTTTTAGCCCATGATAAGTAATATGGGCAGGTAGAAGCAAACTGGAGACTGTCCTGTTAATGCTGC ATGGGGCACAATGTCTTTCAAATTATTGGTGGAAGAATCTCTTTTATCCATGGCGAGAGGTAAGAATATTAAAGAGTCAGGATATTGTTG CTCCTGGTATTTAACAACTGTCATTAGAAATGCTGAAATTTAATTGTAGAGAAGTCAAGAAAGAAAGAGTAAACTGAGAAAATCTTACTA CTACAGAGTCACTTTTACAATGAGACCTGCACTTTATGCCAGCACTGTTTGTGAGGAGCAGTACTGCCTTAAATTAGTTTGACTCTGACT GATGTCAGTGTACGTTACTTCCTTTATGTGACTGACAGTCAGCTTTCCATTGAGATATAACATTCACAGATGATCCCCAAGTATCCTTGT CATCAGAAGCTTTGGACCTTTTCTGCCACTGACTTGTGGCTGATCTGTAACACAATAAATACATAATTTTATTTCATGTTGTCTGTCCAC CTCTGAATAAGCAGTGGCATGACCAAAAAGACTGGTAGAAGGAGAGAATTTCTTGGCCAAATCCTTCATACCAGGTACCACTTCTTGAGT AACTGAGAGTTGACTGTCTTCTATGGTGACTACATAGAAGATATTTCCAAAGGTTCTGTTATGCAGTGAAGACATTCAGATTATTTGTAA GAATTTCACCAACACCCTTGTGTATTGAAATGCTTAACCATTAACAGGGAAAAAAAAGGAGAAAACCGAACAAAACAGAGACATTTACTT GAAATGGGAGGTTTGCTAATGTGAAGAGTGTTTCTGTTTTATTACTTATAAGAGAAAAGCAGGAAAACTTTTGCTTTGATAAGAAAGACA CCAGAGTGGTGATTCTGTTTGATGCCACAGGCTAACACAATCGTGTAATCATGTTGAGTTGTAGAAATATATGGCCCTAAAAACCATTCT CTTTCCCTTATATATATAAATATGTGAACACTGCCTAGTAACATTTTAATAGATTTAAGATGCATTTGTACATTCTCAGCAAACTAGAAG AAAATGTTTTTTCTCTTTTTGAGTTAACTTCATAGCATAGAGAACCAGCACTGTGCAGGTTTCAGCATTTCAGATAAGGGCATAATTAAT TGTGTAACTTAATGCCCTGTTATTCATTGCTGAGGTTCATATAAAGAATAGAAAAATTGAAAGATGGGTTTGGGCGACATTTTCTTCCCA AAAGATCAAGTAAGGAGTAAGAACAAGTAAGGGAAGACAGCTAAGAGAACATACTATGACATATCATAGAATTGGGATACATTTTTGTTG CACTGGATTTCAGGCTATACTGCTAAAATAATTTCTACCTGTTAAATTTTGTGAGAGGGTTTTTGACATCAGAATTTTTGTATTTCTGGT CAAATTGGTCTTGGAAATCCCTATGGTCTCTAATTTCAGCTCTTGCTGTAAACTGCAAGCCAAATGCTCTTTCTCAGAAAGAGCTATATT TTTCTCTTCTTACAGGCAACCCAATATTTATTTCATAAAGTGTTATAAATATTGAGAAGATACACTGGGGAGATAGCATATAAAAATGAT GCTCCAAAATGAGAATTCTATATGGGGCTTTCCCTAAGAAGAATCCATCCCAGCACATATTTTGAAAAGGTGCTGAATTAAAAAGTACAA GAGTTTGCTCATATAAATCAAGTTGCCCAGGAAACCTGAGGTGATGCTATCATTTGTCTCATAATTTAGAAACGTGATCTCTTGAGAGAG AGACTACGCATTGCCTGGGCACTTTCAGATTCCTTAGGAAGTGCCCCTTTGATATTTGGAATGTGGATATATTTATAAAACAAATGGATT GTTATTCCAAATCCACATGGATTTATAACCAAGCCCCAGAAGAATAGGCAGCTTTGAAATAGCTAGTTCGTGGAATTGAACAGAACCTTG ATGGAATGCAGTTGCCTGTGTGAGGACAGAAAACAAAGAGGCTGCCTCAGACCACATGCCTATCTAGAGATTAAGTGAATTTGTGAGGGA CATTTTGTGGATGCCTTAAAGATGACCAGTGGTGGGTTCTGATGGGAATATATACACTCATCTGGACTAGGCCAATGGAAGCAGTCTCTT TCAGTTCACCTCCGTACAGCACAAGTTGTTCCTGCTCATGACCTCATTGAGGAAAATGAGAATTGTGGTGCTGGTGACTTTCATGTGTCT TGGGAGGTTGAGGTGTTCAACATCGTTAAGGCACTCCCAAAACGCAAACCTCCTTTTTTAAATGCCAATTGTACATCTACATTAATTCAT CTATGCAAACTTGTGTTTTCATGGTTTGTTTTTTACACTATATTTCTCATTAGGTTCTTTAAACATCAGGTTTAATATTGATATTATGAA TAATTTTTAAACCAAAGTATTCTATAAGTCTGTGTGCTTTGTTTTCCTGGATGGTTTGACCAAGGTAAACATCAGTCTTGTCCTTCTCTC TTAATAAAGTCATCCATTTGTTAAGTCAGTGGTCTCTGTCTCATGTTTTTGTTTTGTTTCTTTACAGCATTCAAGGACAGGGAAACTTAC GAGAGTCTTATTATAATTATTATTATTTACAAAATGACCCTAATAGGTCTGTTTAGTAACAGTGAAATTTTTTCTTACTCCATTTCCATA >21704_21704_1_DCUN1D1-CCDC50_DCUN1D1_chr3_182679014_ENST00000292782_CCDC50_chr3_191074877_ENST00000392455_length(amino acids)=468AA_BP=177 MEDTNMNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDG IQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLVC RDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKK DEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQ VAQDEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSS -------------------------------------------------------------- >21704_21704_2_DCUN1D1-CCDC50_DCUN1D1_chr3_182679014_ENST00000292782_CCDC50_chr3_191074877_ENST00000392456_length(transcript)=2489nt_BP=674nt CGAGGTCCGGGGCTGCCTCCTCGGGCCGCGCCGGGCCGCCCCGCACTGCGCATGAGCGGGAGCCGGGCAAGCCCGTGAGAGGAGCCGCCG CCGCCGCCGCCGTCCATTCGCTGCGGAGCCGGAGGAGGAGGGGAGAGGCCTGGAGGACACCAACATGAACAAGTTGAAATCATCGCAGAA GGATAAAGTTCGTCAGTTTATGATCTTCACACAATCTAGTGAAAAAACAGCAGTAAGTTGTCTTTCTCAAAATGACTGGAAGTTAGATGT TGCAACAGATAATTTTTTCCAAAATCCTGAACTTTATATACGAGAGAGTGTAAAAGGATCATTGGACAGGAAGAAGTTAGAACAGCTGTA CAATAGATACAAAGACCCTCAAGATGAGAATAAAATTGGAATAGATGGCATACAGCAGTTCTGTGATGACCTGGCACTCGATCCAGCCAG CATTAGTGTGTTGATTATTGCGTGGAAGTTCAGAGCAGCAACACAGTGCGAGTTCTCCAAACAGGAGTTCATGGATGGCATGACAGAATT AGGATGTGACAGCATAGAAAAACTAAAGGCCCAGATACCCAAGATGGAACAAGAATTGAAAGAACCAGGACGATTTAAGGATTTTTACCA GTTTACTTTTAATTTTGCAAAGAATCCAGGACAAAAAGGATTAGTATGCCGAGATTTTGCTGTCCTGGAGGACCACACCCTGGCTCACAG CCTGCAGGAACAAGAGATTGAGCATCATTTGGCATCGAACGTTCAGCGGAACCGTTTGGTCCAGCATGATCTCCAGGTGGCTAAGCAGCT CCAAGAGGAAGATCTGAAAGCGCAGGCCCAGCTCCAGAAGCGCTACAAAGACCTTGAACAACAAGACTGTGAAATTGCTCAGGAAATTCA GGAGAAGCTGGCTATTGAGGCAGAGAGACGACGCATTCAGGAGAAGAAGGATGAGGACATAGCTCGCCTTTTGCAAGAAAAGGAGTTACA GGAAGAGAAAAAGAGAAAGAAACACTTTCCAGAGTTCCCTGCAACCCGTGCTTATGCAGATAGTTACTATTATGAAGATGGAGACCAACC AGGGTCAAGGAGGGCCAGGGAATTGGGTTCTGGATTCTCAAGACCTTGTAGACTCCAAAGAGATGGAAAGACTGTGAAGCACAAGAAAGA GAAACCAGAACATCCACTGGAGAACTTGGAAGAGCCAGAACAACATTGTTCATCGAAGAGATCCCTGTCATCCTCTAGCTCGGGCAAAGG GAGGGACAATCCCCATATTAACAATGAGCAGCATGAAAGGAAACGGTCCACTCAGGAGAGGCCTCGGAGACCTCTGCTTCCCACGATCAG TGGTGAAGTGTTTCTGAGCACTGAATGTGATGACTGGGAGACTAAGATTAACCATCAGACTCGAAATTGGGAAAAACAGTCTCGACACCA AGATCGACTTTCACCCAAGTCCTCACAAAAAGCAGGGCTTCACTGCAAGGAAGTTGTATATGGGAGGGACCATGGGCAAGGTGAGCACAG AAAAAGGAGACACAGGCCCAGGACTCCTCCATTCTCAGAGAGTGAGGAGCAGCTCCACCTCCATGACGCAGGAATGAAGCCAAGAGTGAT GAAAGAAGCTGTATCTACTCCATCACGAATGGCCCACAGGGATCAGGAATGGTATGATGCTGAAATTGCCAGAAAACTGCAAGAAGAAGA ACTTTTGGCTACCCAGGTGGACATGAGAGCCGCTCAAGTAGCTCAAGATGAAGAAATCGCTCGACTTCTAATGGCTGAAGAAAAGAAAGC TTACAAAAAAGCCAAGGAGCGGGAGAAATCATCTTTGGACAAAAGAAAGCAAGACCCCGAGTGGAAGCCAAAAACAGCTAAAGCAGCAAA TTCCAAGTCAAAAGAGAGTGATGAACCTCACCATTCTAAGAATGAAAGGCCAGCACGGCCACCACCACCTATCATGACAGATGGTGAAGA TGCGGATTACACTCATTTTACAAACCAGCAGAGTTCCACACGGCATTTCTCAAAATCAGAGTCCTCTCATAAAGGTTTTCATTACAAACA TTAAAAACCTAGGAATCTGCCTTGAAAATGGACTCACTATAGCAAATATTACTGGGTGATACAGAATGAATTCTACACTTACTTTTTTTC TCCTGTGTTTGCATTCCTGGGATTTATCCTCAAGTGCATTTCTGACCATAAGTAATTTTAATTCATTTCAAATGTTTTGGTTATTCATGA TCACTTGGGCAGTATAAGAAAATGTAGCTTCTGAATATTGGCCACCTCTATGCTGCATATACTTCTTGGGATATAGTATCTAAGACCTTT GTAAACTGCCATTTTGTTAGGTATGGAGTTTGGTATCTAGGGAGTAGGCCTTATTTAGCAATTCAAATTTTATGGAGATGAATGATCAAA >21704_21704_2_DCUN1D1-CCDC50_DCUN1D1_chr3_182679014_ENST00000292782_CCDC50_chr3_191074877_ENST00000392456_length(amino acids)=644AA_BP=177 MEDTNMNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDG IQQFCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLVC RDFAVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKK DEDIARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQHC SSKRSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCK EVVYGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQD EEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHF -------------------------------------------------------------- >21704_21704_3_DCUN1D1-CCDC50_DCUN1D1_chr3_182679014_ENST00000469954_CCDC50_chr3_191074877_ENST00000392455_length(transcript)=8432nt_BP=650nt GGTGGTCTTGGACAGTTTCTCATTGCTGGGTCTCCACTCCTAGCTGTTACTGCAAGTCCATGCCTCTACCATGAGGGTGGAGGAGTTAAG ATCAACAGATCCACATGTACCTTGAGGTGACAGACTGGCTCTGAACAAGTTGAAATCATCGCAGAAGGATAAAGTTCGTCAGTTTATGAT CTTCACACAATCTAGTGAAAAAACAGCAGTAAGTTGTCTTTCTCAAAATGACTGGAAGTTAGATGTTGCAACAGATAATTTTTTCCAAAA TCCTGAACTTTATATACGAGAGAGTGTAAAAGGATCATTGGACAGGAAGAAGTTAGAACAGCTGTACAATAGATACAAAGACCCTCAAGA TGAGAATAAAATTGGAATAGATGGCATACAGCAGTTCTGTGATGACCTGGCACTCGATCCAGCCAGCATTAGTGTGTTGATTATTGCGTG GAAGTTCAGAGCAGCAACACAGTGCGAGTTCTCCAAACAGGAGTTCATGGATGGCATGACAGAATTAGGATGTGACAGCATAGAAAAACT AAAGGCCCAGATACCCAAGATGGAACAAGAATTGAAAGAACCAGGACGATTTAAGGATTTTTACCAGTTTACTTTTAATTTTGCAAAGAA TCCAGGACAAAAAGGATTAGTATGCCGAGATTTTGCTGTCCTGGAGGACCACACCCTGGCTCACAGCCTGCAGGAACAAGAGATTGAGCA TCATTTGGCATCGAACGTTCAGCGGAACCGTTTGGTCCAGCATGATCTCCAGGTGGCTAAGCAGCTCCAAGAGGAAGATCTGAAAGCGCA GGCCCAGCTCCAGAAGCGCTACAAAGACCTTGAACAACAAGACTGTGAAATTGCTCAGGAAATTCAGGAGAAGCTGGCTATTGAGGCAGA GAGACGACGCATTCAGGAGAAGAAGGATGAGGACATAGCTCGCCTTTTGCAAGAAAAGGAGTTACAGGAAGAGAAAAAGAGAAAGAAACA CTTTCCAGAGTTCCCTGCAACCCGTGCTTATGCAGATAGTTACTATTATGAAGATGGAGGAATGAAGCCAAGAGTGATGAAAGAAGCTGT ATCTACTCCATCACGAATGGCCCACAGGGATCAGGAATGGTATGATGCTGAAATTGCCAGAAAACTGCAAGAAGAAGAACTTTTGGCTAC CCAGGTGGACATGAGAGCCGCTCAAGTAGCTCAAGATGAAGAAATCGCTCGACTTCTAATGGCTGAAGAAAAGAAAGCTTACAAAAAAGC CAAGGAGCGGGAGAAATCATCTTTGGACAAAAGAAAGCAAGACCCCGAGTGGAAGCCAAAAACAGCTAAAGCAGCAAATTCCAAGTCAAA AGAGAGTGATGAACCTCACCATTCTAAGAATGAAAGGCCAGCACGGCCACCACCACCTATCATGACAGATGGTGAAGATGCGGATTACAC TCATTTTACAAACCAGCAGAGTTCCACACGGCATTTCTCAAAATCAGAGTCCTCTCATAAAGGTTTTCATTACAAACATTAAAAACCTAG GAATCTGCCTTGAAAATGGACTCACTATAGCAAATATTACTGGGTGATACAGAATGAATTCTACACTTACTTTTTTTCTCCTGTGTTTGC ATTCCTGGGATTTATCCTCAAGTGCATTTCTGACCATAAGTAATTTTAATTCATTTCAAATGTTTTGGTTATTCATGATCACTTGGGCAG TATAAGAAAATGTAGCTTCTGAATATTGGCCACCTCTATGCTGCATATACTTCTTGGGATATAGTATCTAAGACCTTTGTAAACTGCCAT TTTGTTAGGTATGGAGTTTGGTATCTAGGGAGTAGGCCTTATTTAGCAATTCAAATTTTATGGAGATGAATGATCAAAGTGAAACAATGT TTGGATGCAACGCAGAATAAAAGAATATAAGAAATAGCTTTTTGTTGCATTAATGTATGATATTTTGAAGGACAGAGCCTTTGCTTTTTG TATTCTTTAAGAAAAGCACAACCATAAAGTATTTTAAAAAAAGAAACACTTGGAGCAATTGAAATATGTTATTCTGACTAGATGGACTGT AGAGGTTTTGCATTTCTCAGCCCTCCTGGGGAGATTGGCCTAGATAGCATTCTTTAACACTTCCTCTGCTTTTGCCTCAGTAGCAAGGCT TTCCTAAGCTCCTGGGCAATGGAACATTTATTAGTATTTATTGACAAAAATTTAGTTCTCTGAAATTTTAACTCATATATATGAAAAACT TTGTATTCCATCTCTTCTTTTTCATTTACTTGTAGAGCCAAGGAAATGGAATTGAAAGATGATTGCATAAGTAATGATGCCATCCTTCTC TCTGGCTGTAGACTGAGGCTTTTCTCTTGCTTCAAGTCAGAGCAGTATTTGTTGATAACCTCTCAATAATGTTTGGTTTACATGCCAGTA ATTAAATTAATTCAACATGAAGTTGAATTTGATGAAGTGGTCATCTATCCAAGTATTTGGTTTTTGTTTTGTTTTGTTTTGTTTTTTGAG TTGGAGTCTCGCCCTGTCACACAGGCTGGAGTGCAGTGGTGCAATCTTGGCTCACTGCAACCTCCGCCACCTGGGCTGGAGCAATTCCCC TGCCTCAGCCTCCCAAGTAGCTGGAATTACAGGCATGTGTCACCACACCCGGCTAATTTTTGTATTTTTAGTAAAGAGCGGGTTTCACCA TGTTGGCCAGGCTGGTCTCGAACCCCTGACCTCAAGTGATCCACCTGCCTTGGCCTCCCAAGGTGCTGGGATTACAGGCTTAAGCCACCA TGTCCAGCCAGCCAAGTATTTGGTTTTAAACATTTGTATTCCTTTGTGCAAGGGATTGTATTCCTCTGTACAAGACCTTTAAGCACCTCT TCAAGAAATTTAGTCTTTGTGTAGCTGCTAACCTTACTGCAATATTTATTTTCCCTTATTTTCCCATACTACTTAGTTGACAAATGGCAA TCAAGCTCACTTGTTCTCCCTCTCTCTGTCTCCCCCCCATGTACACATATATATATCCCTTCAGCTTGACTTGCTATTATTTTTCATTGT ATAAATATGAAATTCTTGGCATTTCAATATGGCATTTGTTTAGGGAAAAAATATGTAGGTCACTAGAGAAAAATGTTAATTTTTTTCCCA CTGTGAATTGCCTTCTGTTTGCCTTATCTTTTCAGATAGTCTTTAAAGTTGGGCAATATTCAGGCAGCTATTTAGAACAGTTTCTCAGAG TGGATTTGGGTCTCTCATTTGAGAAAGATTTGTAGTTTCAATGAAGTTTGTATATTATAGGAATTTAAGTAAAATCATCTGAGTTAAGTT TTGGGCAAATGTTAATCAGAAAGATAATCTACATCCCTACTTTATGTAGTCATTTTGGAGAAATGGAGGAAAAGGAAAATAACAGGACTT TTTATAGCTGTGATAAAATGGGTAAAGAAAAACCTCCATTTAAATAAGGAAGGGGAGACAAAATGGAAGGTCCTGGCCTTAAGTCAAATT CCAGATAGTGCTTTCAATATCCAAAGCTTAGGCCTTGTTTACTTATAGTAATGCTATATTTTTCTTTATCTGCCCTGTGATTTCGCTTCG TGTCCTTCAAAGTTTTTTTATTGTAATTTTAAAGGAAAAAAACAATGTATTTTTATTTGATAACTAGGCAAAATCATTTGCCATTTTTTA TTTCATAAATATTTATTTTTCTATCTCATACAATGATCAGTTTTACTTTAAAAATTCTGCATTTCTCTTGCCTCTCATGTACTTCATCCA GTTATTTATTATTGTAAAATGTTAACTGGAGATACTGCATTCAAAAAAAAGTCGGACCACTTAACACTTACCAGGAATGTTAGTGTTTCA GCTGTTTTAGTAAGTGACCAAGTAAGCTATCACCTTGTGATAGCTAATTCAACATCTTTATTGAAAATTTGTTACTTTTTTTAAAGGTTT TTAAAAGATTACAATTTTAAAATATTTTATGTTTATTTTATTTTTGTGTAAAGCAAACACTTTTAAAATAATATCAGAGTAATTATTACC CTATGAATAAGGAGATAGAAATGAAATTCAGCCAGTTAAATCCTCATACTCTTTCTCATTCAAATAATATAATAATGTTTGAGACTATAG AAGCAACTCAACTGTATTTTAATGAACTGCCAGACACTTTTCACTGTGTTCTCTGCTTTTTACTTTGTCATTTTTATATAAATGTGAAAG CATTTTGTTGTTGTTGTTGTTGTTCCTGCTGCTAGAACACATGCAGTTTAATTTTTAGGCCCACAGTGTATTATGCTTTAATGTTGTGAT GTAAACTAATACTTCTGGCCTGGGAAAACCTTTCTGTTTCTGTATCTTTGTCCTTTGGAGGCCAGGCCTCATTAACACCAGTATTGTTGA ATAAGCACAATATATGACGGAGCCTTATCATAAGGCTGCTTGACATAGACACCCACTCTCCTCCACATTTTATAAATCATTGTTTGGAAG TAAAGTTAGATAAGAGTCAAATTAAATGTTTTGACTTGAAAAATATTTGACTTTTGCGTTCAAACCACTGTTAGACGTAAGTATTTTATT AGACATAAGTATTTTATTTTGGGACTAGACAGTTGCTTTACATGTATTTAAGGGAACATTGTGATTTTCAGAAAGTGGCTTTACATACTA TTGAATTGCTATTTCCCAAGTTACTTTACAACCAGCAGCAGCATACCAATAAATTACAAAAGCAGAAAATGAAAATTAACCCTAGGTGTT CTGATGATAGAGAAATAGCTAAATTAGAAAAGAAAGATATGGATAGATGCTTTTAGGAGGAAAACCTTTTTAGAATGGCAATGACCACTT GGATCTAGGTCAACATATTCCAAAATGTGTGACCTTGGGCTTTGTGTTTACTGAACTCACTCTAGAAAATTCTGGACCTGATTCATTAAC CCCGCTTTTCTTCTCTAATGTGTCCTGAAGCTGAGCTAGATGATGAGTAAATTCTTTGCTGACTGTTGCTCATCACTTTCTCTCAAAGTT AGAACTTTTCAGTATAAAAATAATTAGCTTTTAACTGATTATTAATTTTCTTTAATAGTTTCTGTCAAAACTTGTCTAAAATTTGTGTTG TGCCAAATTGGAAATACCCACTATAATATGGTGCATTCAGTTTACTCCACAAGTGGTTAACATTTTAAGTCCTAGATTTTTTATGTCTTG CCTTTGTATAAGCATCGCTTTGGGGAATACCAAGATGATTCATTATTCAGTGATTATTTTCTTGAAAGATAACTATGATGATTGGCTGTA AAATCTTCACCCTAATAAAGGAGTGAGATCTCTGTGTAAACAGCTTTCTGAAGGACTGATAATAGAATAGAACTTGCAGCCAAAGGCTTT TTCCCTTTTGAGAAGACGGTATTTGTGTAAGGAGTGCTAAGGTAGACTTCATTGTACATAGAGTGCCATATTCTGTTGAAACGATCATAA CAAAATCAAAACCTCATGCTTCAGCAAAAAGGAAAAAAGATTTTTAAATTACTTTGTCTATTACTTACTGCTCATAGAGAAGTGACTATA TAAAATGGTCCAATTTTCTCATTTCTGGTGGTGCCTGTGAGTCTTAAAGCCATATCTGCTTATCTTACTGTTGATAGAATACTTTTTTTC TTTTTAGCCCATGATAAGTAATATGGGCAGGTAGAAGCAAACTGGAGACTGTCCTGTTAATGCTGCATGGGGCACAATGTCTTTCAAATT ATTGGTGGAAGAATCTCTTTTATCCATGGCGAGAGGTAAGAATATTAAAGAGTCAGGATATTGTTGCTCCTGGTATTTAACAACTGTCAT TAGAAATGCTGAAATTTAATTGTAGAGAAGTCAAGAAAGAAAGAGTAAACTGAGAAAATCTTACTACTACAGAGTCACTTTTACAATGAG ACCTGCACTTTATGCCAGCACTGTTTGTGAGGAGCAGTACTGCCTTAAATTAGTTTGACTCTGACTGATGTCAGTGTACGTTACTTCCTT TATGTGACTGACAGTCAGCTTTCCATTGAGATATAACATTCACAGATGATCCCCAAGTATCCTTGTCATCAGAAGCTTTGGACCTTTTCT GCCACTGACTTGTGGCTGATCTGTAACACAATAAATACATAATTTTATTTCATGTTGTCTGTCCACCTCTGAATAAGCAGTGGCATGACC AAAAAGACTGGTAGAAGGAGAGAATTTCTTGGCCAAATCCTTCATACCAGGTACCACTTCTTGAGTAACTGAGAGTTGACTGTCTTCTAT GGTGACTACATAGAAGATATTTCCAAAGGTTCTGTTATGCAGTGAAGACATTCAGATTATTTGTAAGAATTTCACCAACACCCTTGTGTA TTGAAATGCTTAACCATTAACAGGGAAAAAAAAGGAGAAAACCGAACAAAACAGAGACATTTACTTGAAATGGGAGGTTTGCTAATGTGA AGAGTGTTTCTGTTTTATTACTTATAAGAGAAAAGCAGGAAAACTTTTGCTTTGATAAGAAAGACACCAGAGTGGTGATTCTGTTTGATG CCACAGGCTAACACAATCGTGTAATCATGTTGAGTTGTAGAAATATATGGCCCTAAAAACCATTCTCTTTCCCTTATATATATAAATATG TGAACACTGCCTAGTAACATTTTAATAGATTTAAGATGCATTTGTACATTCTCAGCAAACTAGAAGAAAATGTTTTTTCTCTTTTTGAGT TAACTTCATAGCATAGAGAACCAGCACTGTGCAGGTTTCAGCATTTCAGATAAGGGCATAATTAATTGTGTAACTTAATGCCCTGTTATT CATTGCTGAGGTTCATATAAAGAATAGAAAAATTGAAAGATGGGTTTGGGCGACATTTTCTTCCCAAAAGATCAAGTAAGGAGTAAGAAC AAGTAAGGGAAGACAGCTAAGAGAACATACTATGACATATCATAGAATTGGGATACATTTTTGTTGCACTGGATTTCAGGCTATACTGCT AAAATAATTTCTACCTGTTAAATTTTGTGAGAGGGTTTTTGACATCAGAATTTTTGTATTTCTGGTCAAATTGGTCTTGGAAATCCCTAT GGTCTCTAATTTCAGCTCTTGCTGTAAACTGCAAGCCAAATGCTCTTTCTCAGAAAGAGCTATATTTTTCTCTTCTTACAGGCAACCCAA TATTTATTTCATAAAGTGTTATAAATATTGAGAAGATACACTGGGGAGATAGCATATAAAAATGATGCTCCAAAATGAGAATTCTATATG GGGCTTTCCCTAAGAAGAATCCATCCCAGCACATATTTTGAAAAGGTGCTGAATTAAAAAGTACAAGAGTTTGCTCATATAAATCAAGTT GCCCAGGAAACCTGAGGTGATGCTATCATTTGTCTCATAATTTAGAAACGTGATCTCTTGAGAGAGAGACTACGCATTGCCTGGGCACTT TCAGATTCCTTAGGAAGTGCCCCTTTGATATTTGGAATGTGGATATATTTATAAAACAAATGGATTGTTATTCCAAATCCACATGGATTT ATAACCAAGCCCCAGAAGAATAGGCAGCTTTGAAATAGCTAGTTCGTGGAATTGAACAGAACCTTGATGGAATGCAGTTGCCTGTGTGAG GACAGAAAACAAAGAGGCTGCCTCAGACCACATGCCTATCTAGAGATTAAGTGAATTTGTGAGGGACATTTTGTGGATGCCTTAAAGATG ACCAGTGGTGGGTTCTGATGGGAATATATACACTCATCTGGACTAGGCCAATGGAAGCAGTCTCTTTCAGTTCACCTCCGTACAGCACAA GTTGTTCCTGCTCATGACCTCATTGAGGAAAATGAGAATTGTGGTGCTGGTGACTTTCATGTGTCTTGGGAGGTTGAGGTGTTCAACATC GTTAAGGCACTCCCAAAACGCAAACCTCCTTTTTTAAATGCCAATTGTACATCTACATTAATTCATCTATGCAAACTTGTGTTTTCATGG TTTGTTTTTTACACTATATTTCTCATTAGGTTCTTTAAACATCAGGTTTAATATTGATATTATGAATAATTTTTAAACCAAAGTATTCTA TAAGTCTGTGTGCTTTGTTTTCCTGGATGGTTTGACCAAGGTAAACATCAGTCTTGTCCTTCTCTCTTAATAAAGTCATCCATTTGTTAA GTCAGTGGTCTCTGTCTCATGTTTTTGTTTTGTTTCTTTACAGCATTCAAGGACAGGGAAACTTACGAGAGTCTTATTATAATTATTATT ATTTACAAAATGACCCTAATAGGTCTGTTTAGTAACAGTGAAATTTTTTCTTACTCCATTTCCATACACTTTCTGTAAATATGTATAACA >21704_21704_3_DCUN1D1-CCDC50_DCUN1D1_chr3_182679014_ENST00000469954_CCDC50_chr3_191074877_ENST00000392455_length(amino acids)=465AA_BP=174 MALNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQ FCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLVCRDF AVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDED IARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQ DEEIARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRH -------------------------------------------------------------- >21704_21704_4_DCUN1D1-CCDC50_DCUN1D1_chr3_182679014_ENST00000469954_CCDC50_chr3_191074877_ENST00000392456_length(transcript)=2465nt_BP=650nt GGTGGTCTTGGACAGTTTCTCATTGCTGGGTCTCCACTCCTAGCTGTTACTGCAAGTCCATGCCTCTACCATGAGGGTGGAGGAGTTAAG ATCAACAGATCCACATGTACCTTGAGGTGACAGACTGGCTCTGAACAAGTTGAAATCATCGCAGAAGGATAAAGTTCGTCAGTTTATGAT CTTCACACAATCTAGTGAAAAAACAGCAGTAAGTTGTCTTTCTCAAAATGACTGGAAGTTAGATGTTGCAACAGATAATTTTTTCCAAAA TCCTGAACTTTATATACGAGAGAGTGTAAAAGGATCATTGGACAGGAAGAAGTTAGAACAGCTGTACAATAGATACAAAGACCCTCAAGA TGAGAATAAAATTGGAATAGATGGCATACAGCAGTTCTGTGATGACCTGGCACTCGATCCAGCCAGCATTAGTGTGTTGATTATTGCGTG GAAGTTCAGAGCAGCAACACAGTGCGAGTTCTCCAAACAGGAGTTCATGGATGGCATGACAGAATTAGGATGTGACAGCATAGAAAAACT AAAGGCCCAGATACCCAAGATGGAACAAGAATTGAAAGAACCAGGACGATTTAAGGATTTTTACCAGTTTACTTTTAATTTTGCAAAGAA TCCAGGACAAAAAGGATTAGTATGCCGAGATTTTGCTGTCCTGGAGGACCACACCCTGGCTCACAGCCTGCAGGAACAAGAGATTGAGCA TCATTTGGCATCGAACGTTCAGCGGAACCGTTTGGTCCAGCATGATCTCCAGGTGGCTAAGCAGCTCCAAGAGGAAGATCTGAAAGCGCA GGCCCAGCTCCAGAAGCGCTACAAAGACCTTGAACAACAAGACTGTGAAATTGCTCAGGAAATTCAGGAGAAGCTGGCTATTGAGGCAGA GAGACGACGCATTCAGGAGAAGAAGGATGAGGACATAGCTCGCCTTTTGCAAGAAAAGGAGTTACAGGAAGAGAAAAAGAGAAAGAAACA CTTTCCAGAGTTCCCTGCAACCCGTGCTTATGCAGATAGTTACTATTATGAAGATGGAGACCAACCAGGGTCAAGGAGGGCCAGGGAATT GGGTTCTGGATTCTCAAGACCTTGTAGACTCCAAAGAGATGGAAAGACTGTGAAGCACAAGAAAGAGAAACCAGAACATCCACTGGAGAA CTTGGAAGAGCCAGAACAACATTGTTCATCGAAGAGATCCCTGTCATCCTCTAGCTCGGGCAAAGGGAGGGACAATCCCCATATTAACAA TGAGCAGCATGAAAGGAAACGGTCCACTCAGGAGAGGCCTCGGAGACCTCTGCTTCCCACGATCAGTGGTGAAGTGTTTCTGAGCACTGA ATGTGATGACTGGGAGACTAAGATTAACCATCAGACTCGAAATTGGGAAAAACAGTCTCGACACCAAGATCGACTTTCACCCAAGTCCTC ACAAAAAGCAGGGCTTCACTGCAAGGAAGTTGTATATGGGAGGGACCATGGGCAAGGTGAGCACAGAAAAAGGAGACACAGGCCCAGGAC TCCTCCATTCTCAGAGAGTGAGGAGCAGCTCCACCTCCATGACGCAGGAATGAAGCCAAGAGTGATGAAAGAAGCTGTATCTACTCCATC ACGAATGGCCCACAGGGATCAGGAATGGTATGATGCTGAAATTGCCAGAAAACTGCAAGAAGAAGAACTTTTGGCTACCCAGGTGGACAT GAGAGCCGCTCAAGTAGCTCAAGATGAAGAAATCGCTCGACTTCTAATGGCTGAAGAAAAGAAAGCTTACAAAAAAGCCAAGGAGCGGGA GAAATCATCTTTGGACAAAAGAAAGCAAGACCCCGAGTGGAAGCCAAAAACAGCTAAAGCAGCAAATTCCAAGTCAAAAGAGAGTGATGA ACCTCACCATTCTAAGAATGAAAGGCCAGCACGGCCACCACCACCTATCATGACAGATGGTGAAGATGCGGATTACACTCATTTTACAAA CCAGCAGAGTTCCACACGGCATTTCTCAAAATCAGAGTCCTCTCATAAAGGTTTTCATTACAAACATTAAAAACCTAGGAATCTGCCTTG AAAATGGACTCACTATAGCAAATATTACTGGGTGATACAGAATGAATTCTACACTTACTTTTTTTCTCCTGTGTTTGCATTCCTGGGATT TATCCTCAAGTGCATTTCTGACCATAAGTAATTTTAATTCATTTCAAATGTTTTGGTTATTCATGATCACTTGGGCAGTATAAGAAAATG TAGCTTCTGAATATTGGCCACCTCTATGCTGCATATACTTCTTGGGATATAGTATCTAAGACCTTTGTAAACTGCCATTTTGTTAGGTAT GGAGTTTGGTATCTAGGGAGTAGGCCTTATTTAGCAATTCAAATTTTATGGAGATGAATGATCAAAGTGAAACAATGTTTGGATGCAACG >21704_21704_4_DCUN1D1-CCDC50_DCUN1D1_chr3_182679014_ENST00000469954_CCDC50_chr3_191074877_ENST00000392456_length(amino acids)=641AA_BP=174 MALNKLKSSQKDKVRQFMIFTQSSEKTAVSCLSQNDWKLDVATDNFFQNPELYIRESVKGSLDRKKLEQLYNRYKDPQDENKIGIDGIQQ FCDDLALDPASISVLIIAWKFRAATQCEFSKQEFMDGMTELGCDSIEKLKAQIPKMEQELKEPGRFKDFYQFTFNFAKNPGQKGLVCRDF AVLEDHTLAHSLQEQEIEHHLASNVQRNRLVQHDLQVAKQLQEEDLKAQAQLQKRYKDLEQQDCEIAQEIQEKLAIEAERRRIQEKKDED IARLLQEKELQEEKKRKKHFPEFPATRAYADSYYYEDGDQPGSRRARELGSGFSRPCRLQRDGKTVKHKKEKPEHPLENLEEPEQHCSSK RSLSSSSSGKGRDNPHINNEQHERKRSTQERPRRPLLPTISGEVFLSTECDDWETKINHQTRNWEKQSRHQDRLSPKSSQKAGLHCKEVV YGRDHGQGEHRKRRHRPRTPPFSESEEQLHLHDAGMKPRVMKEAVSTPSRMAHRDQEWYDAEIARKLQEEELLATQVDMRAAQVAQDEEI ARLLMAEEKKAYKKAKEREKSSLDKRKQDPEWKPKTAKAANSKSKESDEPHHSKNERPARPPPPIMTDGEDADYTHFTNQQSSTRHFSKS -------------------------------------------------------------- |
Top |
Fusion Gene PPI Analysis for DCUN1D1-CCDC50 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
Top |
Related Drugs for DCUN1D1-CCDC50 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
Top |
Related Diseases for DCUN1D1-CCDC50 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
Copyright 2021-Present -The University of Texas Health Science Center at Houston (UTHealth)
Web File Viewing | Emergency Information |Campus Carry|Site Policies