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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DENND1A-ASTN2 (FusionGDB2 ID:22190)

Fusion Gene Summary for DENND1A-ASTN2

check button Fusion gene summary
Fusion gene informationFusion gene name: DENND1A-ASTN2
Fusion gene ID: 22190
HgeneTgene
Gene symbol

DENND1A

ASTN2

Gene ID

57706

23245

Gene nameDENN domain containing 1Aastrotactin 2
SynonymsFAM31A|KIAA1608bA67K19.1
Cytomap

9q33.3

9q33.1

Type of geneprotein-codingprotein-coding
DescriptionDENN domain-containing protein 1ADENN/MADD domain containing 1Aconnecdenn 1astrotactin-2
Modification date2020032020200313
UniProtAcc

Q8TEH3

O75129

Ensembl transtripts involved in fusion geneENST00000373618, ENST00000373620, 
ENST00000373624, ENST00000394215, 
ENST00000394219, ENST00000473039, 
ENST00000542603, 		ENST00000358637, 
ENST00000288520, ENST00000313400, 
ENST00000341734, ENST00000361209, 
ENST00000361477, ENST00000373996, 
Fusion gene scores* DoF score18 X 18 X 14=453620 X 19 X 8=3040
# samples 2625
** MAII scorelog2(26/4536*10)=-4.12483711191377
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(25/3040*10)=-3.60407132366886
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DENND1A [Title/Abstract] AND ASTN2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDENND1A(126319849)-ASTN2(119188367), # samples:3
Anticipated loss of major functional domain due to fusion event.DENND1A-ASTN2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
DENND1A-ASTN2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneDENND1A

GO:0032483

regulation of Rab protein signal transduction

20937701


check buttonFusion gene breakpoints across DENND1A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ASTN2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LGGTCGA-DH-A66B-01ADENND1Achr9

126319849

-ASTN2chr9

119188367

-
ChimerDB4LGGTCGA-DH-A66BDENND1Achr9

126319848

-ASTN2chr9

119188367

-
ChimerDB4LGGTCGA-DH-A66BDENND1Achr9

126319849

-ASTN2chr9

119188367

-


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Fusion Gene ORF analysis for DENND1A-ASTN2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000373618ENST00000358637DENND1Achr9

126319849

-ASTN2chr9

119188367

-
5CDS-intronENST00000373618ENST00000358637DENND1Achr9

126319848

-ASTN2chr9

119188367

-
5CDS-intronENST00000373620ENST00000358637DENND1Achr9

126319849

-ASTN2chr9

119188367

-
5CDS-intronENST00000373620ENST00000358637DENND1Achr9

126319848

-ASTN2chr9

119188367

-
5CDS-intronENST00000373624ENST00000358637DENND1Achr9

126319849

-ASTN2chr9

119188367

-
5CDS-intronENST00000373624ENST00000358637DENND1Achr9

126319848

-ASTN2chr9

119188367

-
5CDS-intronENST00000394215ENST00000358637DENND1Achr9

126319849

-ASTN2chr9

119188367

-
5CDS-intronENST00000394215ENST00000358637DENND1Achr9

126319848

-ASTN2chr9

119188367

-
5CDS-intronENST00000394219ENST00000358637DENND1Achr9

126319849

-ASTN2chr9

119188367

-
5CDS-intronENST00000394219ENST00000358637DENND1Achr9

126319848

-ASTN2chr9

119188367

-
5UTR-3CDSENST00000473039ENST00000288520DENND1Achr9

126319849

-ASTN2chr9

119188367

-
5UTR-3CDSENST00000473039ENST00000288520DENND1Achr9

126319848

-ASTN2chr9

119188367

-
5UTR-3CDSENST00000473039ENST00000313400DENND1Achr9

126319849

-ASTN2chr9

119188367

-
5UTR-3CDSENST00000473039ENST00000313400DENND1Achr9

126319848

-ASTN2chr9

119188367

-
5UTR-3CDSENST00000473039ENST00000341734DENND1Achr9

126319849

-ASTN2chr9

119188367

-
5UTR-3CDSENST00000473039ENST00000341734DENND1Achr9

126319848

-ASTN2chr9

119188367

-
5UTR-3CDSENST00000473039ENST00000361209DENND1Achr9

126319849

-ASTN2chr9

119188367

-
5UTR-3CDSENST00000473039ENST00000361209DENND1Achr9

126319848

-ASTN2chr9

119188367

-
5UTR-3CDSENST00000473039ENST00000361477DENND1Achr9

126319849

-ASTN2chr9

119188367

-
5UTR-3CDSENST00000473039ENST00000361477DENND1Achr9

126319848

-ASTN2chr9

119188367

-
5UTR-3CDSENST00000473039ENST00000373996DENND1Achr9

126319849

-ASTN2chr9

119188367

-
5UTR-3CDSENST00000473039ENST00000373996DENND1Achr9

126319848

-ASTN2chr9

119188367

-
5UTR-intronENST00000473039ENST00000358637DENND1Achr9

126319849

-ASTN2chr9

119188367

-
5UTR-intronENST00000473039ENST00000358637DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000373618ENST00000313400DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000373618ENST00000313400DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000373618ENST00000341734DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000373618ENST00000341734DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000373618ENST00000361477DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000373618ENST00000361477DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000373620ENST00000288520DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000373620ENST00000288520DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000373620ENST00000313400DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000373620ENST00000313400DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000373620ENST00000341734DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000373620ENST00000341734DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000373620ENST00000361209DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000373620ENST00000361209DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000373620ENST00000361477DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000373620ENST00000361477DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000373620ENST00000373996DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000373620ENST00000373996DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000373624ENST00000288520DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000373624ENST00000288520DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000373624ENST00000313400DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000373624ENST00000313400DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000373624ENST00000341734DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000373624ENST00000341734DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000373624ENST00000361209DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000373624ENST00000361209DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000373624ENST00000361477DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000373624ENST00000361477DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000373624ENST00000373996DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000373624ENST00000373996DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000394215ENST00000313400DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000394215ENST00000313400DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000394215ENST00000341734DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000394215ENST00000341734DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000394215ENST00000361477DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000394215ENST00000361477DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000394219ENST00000288520DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000394219ENST00000288520DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000394219ENST00000313400DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000394219ENST00000313400DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000394219ENST00000341734DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000394219ENST00000341734DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000394219ENST00000361209DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000394219ENST00000361209DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000394219ENST00000361477DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000394219ENST00000361477DENND1Achr9

126319848

-ASTN2chr9

119188367

-
Frame-shiftENST00000394219ENST00000373996DENND1Achr9

126319849

-ASTN2chr9

119188367

-
Frame-shiftENST00000394219ENST00000373996DENND1Achr9

126319848

-ASTN2chr9

119188367

-
In-frameENST00000373618ENST00000288520DENND1Achr9

126319849

-ASTN2chr9

119188367

-
In-frameENST00000373618ENST00000288520DENND1Achr9

126319848

-ASTN2chr9

119188367

-
In-frameENST00000373618ENST00000361209DENND1Achr9

126319849

-ASTN2chr9

119188367

-
In-frameENST00000373618ENST00000361209DENND1Achr9

126319848

-ASTN2chr9

119188367

-
In-frameENST00000373618ENST00000373996DENND1Achr9

126319849

-ASTN2chr9

119188367

-
In-frameENST00000373618ENST00000373996DENND1Achr9

126319848

-ASTN2chr9

119188367

-
In-frameENST00000394215ENST00000288520DENND1Achr9

126319849

-ASTN2chr9

119188367

-
In-frameENST00000394215ENST00000288520DENND1Achr9

126319848

-ASTN2chr9

119188367

-
In-frameENST00000394215ENST00000361209DENND1Achr9

126319849

-ASTN2chr9

119188367

-
In-frameENST00000394215ENST00000361209DENND1Achr9

126319848

-ASTN2chr9

119188367

-
In-frameENST00000394215ENST00000373996DENND1Achr9

126319849

-ASTN2chr9

119188367

-
In-frameENST00000394215ENST00000373996DENND1Achr9

126319848

-ASTN2chr9

119188367

-
intron-3CDSENST00000542603ENST00000288520DENND1Achr9

126319849

-ASTN2chr9

119188367

-
intron-3CDSENST00000542603ENST00000288520DENND1Achr9

126319848

-ASTN2chr9

119188367

-
intron-3CDSENST00000542603ENST00000313400DENND1Achr9

126319849

-ASTN2chr9

119188367

-
intron-3CDSENST00000542603ENST00000313400DENND1Achr9

126319848

-ASTN2chr9

119188367

-
intron-3CDSENST00000542603ENST00000341734DENND1Achr9

126319849

-ASTN2chr9

119188367

-
intron-3CDSENST00000542603ENST00000341734DENND1Achr9

126319848

-ASTN2chr9

119188367

-
intron-3CDSENST00000542603ENST00000361209DENND1Achr9

126319849

-ASTN2chr9

119188367

-
intron-3CDSENST00000542603ENST00000361209DENND1Achr9

126319848

-ASTN2chr9

119188367

-
intron-3CDSENST00000542603ENST00000361477DENND1Achr9

126319849

-ASTN2chr9

119188367

-
intron-3CDSENST00000542603ENST00000361477DENND1Achr9

126319848

-ASTN2chr9

119188367

-
intron-3CDSENST00000542603ENST00000373996DENND1Achr9

126319849

-ASTN2chr9

119188367

-
intron-3CDSENST00000542603ENST00000373996DENND1Achr9

126319848

-ASTN2chr9

119188367

-
intron-intronENST00000542603ENST00000358637DENND1Achr9

126319849

-ASTN2chr9

119188367

-
intron-intronENST00000542603ENST00000358637DENND1Achr9

126319848

-ASTN2chr9

119188367

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000394215DENND1Achr9126319849-ENST00000373996ASTN2chr9119188367-204611821171223368
ENST00000394215DENND1Achr9126319849-ENST00000361209ASTN2chr9119188367-204311821171223368
ENST00000394215DENND1Achr9126319849-ENST00000288520ASTN2chr9119188367-204311821171223368
ENST00000373618DENND1Achr9126319849-ENST00000373996ASTN2chr9119188367-205411901311231366
ENST00000373618DENND1Achr9126319849-ENST00000361209ASTN2chr9119188367-205111901311231366
ENST00000373618DENND1Achr9126319849-ENST00000288520ASTN2chr9119188367-205111901311231366
ENST00000394215DENND1Achr9126319848-ENST00000373996ASTN2chr9119188367-204611821171223368
ENST00000394215DENND1Achr9126319848-ENST00000361209ASTN2chr9119188367-204311821171223368
ENST00000394215DENND1Achr9126319848-ENST00000288520ASTN2chr9119188367-204311821171223368
ENST00000373618DENND1Achr9126319848-ENST00000373996ASTN2chr9119188367-205411901311231366
ENST00000373618DENND1Achr9126319848-ENST00000361209ASTN2chr9119188367-205111901311231366
ENST00000373618DENND1Achr9126319848-ENST00000288520ASTN2chr9119188367-205111901311231366

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000394215ENST00000373996DENND1Achr9126319849-ASTN2chr9119188367-0.0018579120.9981421
ENST00000394215ENST00000361209DENND1Achr9126319849-ASTN2chr9119188367-0.0018466940.99815327
ENST00000394215ENST00000288520DENND1Achr9126319849-ASTN2chr9119188367-0.0018466940.99815327
ENST00000373618ENST00000373996DENND1Achr9126319849-ASTN2chr9119188367-0.0042621370.9957379
ENST00000373618ENST00000361209DENND1Achr9126319849-ASTN2chr9119188367-0.0042370760.99576294
ENST00000373618ENST00000288520DENND1Achr9126319849-ASTN2chr9119188367-0.0042370760.99576294
ENST00000394215ENST00000373996DENND1Achr9126319848-ASTN2chr9119188367-0.0018579120.9981421
ENST00000394215ENST00000361209DENND1Achr9126319848-ASTN2chr9119188367-0.0018466940.99815327
ENST00000394215ENST00000288520DENND1Achr9126319848-ASTN2chr9119188367-0.0018466940.99815327
ENST00000373618ENST00000373996DENND1Achr9126319848-ASTN2chr9119188367-0.0042621370.9957379
ENST00000373618ENST00000361209DENND1Achr9126319848-ASTN2chr9119188367-0.0042370760.99576294
ENST00000373618ENST00000288520DENND1Achr9126319848-ASTN2chr9119188367-0.0042370760.99576294

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Fusion Genomic Features for DENND1A-ASTN2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for DENND1A-ASTN2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:126319849/chr9:119188367)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DENND1A

Q8TEH3

ASTN2

O75129

FUNCTION: Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes (PubMed:20154091, PubMed:20937701). Binds phosphatidylinositol-phosphates (PtdInsPs), with some preference for PtdIns(3)P (By similarity). {ECO:0000250|UniProtKB:Q8K382, ECO:0000269|PubMed:20154091, ECO:0000269|PubMed:20937701}.FUNCTION: Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity). Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (Ref.6). {ECO:0000250|UniProtKB:Q80Z10, ECO:0000269|Ref.6}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDENND1Achr9:126319848chr9:119188367ENST00000373618-121913_145299467.0DomainuDENN
HgeneDENND1Achr9:126319848chr9:119188367ENST00000373618-1219162_298299467.0DomaincDENN
HgeneDENND1Achr9:126319848chr9:119188367ENST00000373620-132113_145331560.0DomainuDENN
HgeneDENND1Achr9:126319848chr9:119188367ENST00000373620-1321162_298331560.0DomaincDENN
HgeneDENND1Achr9:126319848chr9:119188367ENST00000373624-132213_1453311010.0DomainuDENN
HgeneDENND1Achr9:126319848chr9:119188367ENST00000373624-1322162_2983311010.0DomaincDENN
HgeneDENND1Achr9:126319848chr9:119188367ENST00000394215-122013_145301530.0DomainuDENN
HgeneDENND1Achr9:126319848chr9:119188367ENST00000394215-1220162_298301530.0DomaincDENN
HgeneDENND1Achr9:126319848chr9:119188367ENST00000394219-112113_1452991021.0DomainuDENN
HgeneDENND1Achr9:126319848chr9:119188367ENST00000394219-1121162_2982991021.0DomaincDENN
HgeneDENND1Achr9:126319849chr9:119188367ENST00000373618-121913_145299467.0DomainuDENN
HgeneDENND1Achr9:126319849chr9:119188367ENST00000373618-1219162_298299467.0DomaincDENN
HgeneDENND1Achr9:126319849chr9:119188367ENST00000373620-132113_145331560.0DomainuDENN
HgeneDENND1Achr9:126319849chr9:119188367ENST00000373620-1321162_298331560.0DomaincDENN
HgeneDENND1Achr9:126319849chr9:119188367ENST00000373624-132213_1453311010.0DomainuDENN
HgeneDENND1Achr9:126319849chr9:119188367ENST00000373624-1322162_2983311010.0DomaincDENN
HgeneDENND1Achr9:126319849chr9:119188367ENST00000394215-122013_145301530.0DomainuDENN
HgeneDENND1Achr9:126319849chr9:119188367ENST00000394215-1220162_298301530.0DomaincDENN
HgeneDENND1Achr9:126319849chr9:119188367ENST00000394219-112113_1452991021.0DomainuDENN
HgeneDENND1Achr9:126319849chr9:119188367ENST00000394219-1121162_2982991021.0DomaincDENN
TgeneASTN2chr9:126319848chr9:119188367ENST00000288520681065_1188361441.0DomainNote=Fibronectin type-III
TgeneASTN2chr9:126319848chr9:119188367ENST0000028852068510_550361441.0DomainNote=EGF-like 1
TgeneASTN2chr9:126319848chr9:119188367ENST0000028852068651_695361441.0DomainNote=EGF-like 2
TgeneASTN2chr9:126319848chr9:119188367ENST0000028852068699_751361441.0DomainNote=EGF-like 3
TgeneASTN2chr9:126319848chr9:119188367ENST00000341734691065_1188312396.0DomainNote=Fibronectin type-III
TgeneASTN2chr9:126319848chr9:119188367ENST0000034173469510_550312396.0DomainNote=EGF-like 1
TgeneASTN2chr9:126319848chr9:119188367ENST0000034173469651_695312396.0DomainNote=EGF-like 2
TgeneASTN2chr9:126319848chr9:119188367ENST0000034173469699_751312396.0DomainNote=EGF-like 3
TgeneASTN2chr9:126319848chr9:119188367ENST0000036147720231065_1188312396.0DomainNote=Fibronectin type-III
TgeneASTN2chr9:126319848chr9:119188367ENST000003614772023510_550312396.0DomainNote=EGF-like 1
TgeneASTN2chr9:126319848chr9:119188367ENST000003614772023651_695312396.0DomainNote=EGF-like 2
TgeneASTN2chr9:126319848chr9:119188367ENST000003614772023699_751312396.0DomainNote=EGF-like 3
TgeneASTN2chr9:126319849chr9:119188367ENST00000288520681065_1188361441.0DomainNote=Fibronectin type-III
TgeneASTN2chr9:126319849chr9:119188367ENST0000028852068510_550361441.0DomainNote=EGF-like 1
TgeneASTN2chr9:126319849chr9:119188367ENST0000028852068651_695361441.0DomainNote=EGF-like 2
TgeneASTN2chr9:126319849chr9:119188367ENST0000028852068699_751361441.0DomainNote=EGF-like 3
TgeneASTN2chr9:126319849chr9:119188367ENST00000341734691065_1188312396.0DomainNote=Fibronectin type-III
TgeneASTN2chr9:126319849chr9:119188367ENST0000034173469510_550312396.0DomainNote=EGF-like 1
TgeneASTN2chr9:126319849chr9:119188367ENST0000034173469651_695312396.0DomainNote=EGF-like 2
TgeneASTN2chr9:126319849chr9:119188367ENST0000034173469699_751312396.0DomainNote=EGF-like 3
TgeneASTN2chr9:126319849chr9:119188367ENST0000036147720231065_1188312396.0DomainNote=Fibronectin type-III
TgeneASTN2chr9:126319849chr9:119188367ENST000003614772023510_550312396.0DomainNote=EGF-like 1
TgeneASTN2chr9:126319849chr9:119188367ENST000003614772023651_695312396.0DomainNote=EGF-like 2
TgeneASTN2chr9:126319849chr9:119188367ENST000003614772023699_751312396.0DomainNote=EGF-like 3
TgeneASTN2chr9:126319848chr9:119188367ENST0000028852068456_1339361441.0Topological domainLumenal
TgeneASTN2chr9:126319848chr9:119188367ENST0000034173469456_1339312396.0Topological domainLumenal
TgeneASTN2chr9:126319848chr9:119188367ENST000003614772023456_1339312396.0Topological domainLumenal
TgeneASTN2chr9:126319849chr9:119188367ENST0000028852068456_1339361441.0Topological domainLumenal
TgeneASTN2chr9:126319849chr9:119188367ENST0000034173469456_1339312396.0Topological domainLumenal
TgeneASTN2chr9:126319849chr9:119188367ENST000003614772023456_1339312396.0Topological domainLumenal
TgeneASTN2chr9:126319848chr9:119188367ENST0000028852068435_455361441.0TransmembraneHelical
TgeneASTN2chr9:126319848chr9:119188367ENST0000034173469435_455312396.0TransmembraneHelical
TgeneASTN2chr9:126319848chr9:119188367ENST000003614772023435_455312396.0TransmembraneHelical
TgeneASTN2chr9:126319849chr9:119188367ENST0000028852068435_455361441.0TransmembraneHelical
TgeneASTN2chr9:126319849chr9:119188367ENST0000034173469435_455312396.0TransmembraneHelical
TgeneASTN2chr9:126319849chr9:119188367ENST000003614772023435_455312396.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDENND1Achr9:126319848chr9:119188367ENST00000373618-1219649_995299467.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126319848chr9:119188367ENST00000373620-1321649_995331560.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126319848chr9:119188367ENST00000373624-1322649_9953311010.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126319848chr9:119188367ENST00000394215-1220649_995301530.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126319848chr9:119188367ENST00000394219-1121649_9952991021.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126319848chr9:119188367ENST00000542603-114649_9950795.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126319849chr9:119188367ENST00000373618-1219649_995299467.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126319849chr9:119188367ENST00000373620-1321649_995331560.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126319849chr9:119188367ENST00000373624-1322649_9953311010.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126319849chr9:119188367ENST00000394215-1220649_995301530.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126319849chr9:119188367ENST00000394219-1121649_9952991021.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126319849chr9:119188367ENST00000542603-114649_9950795.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126319848chr9:119188367ENST00000373618-1219300_378299467.0DomaindDENN
HgeneDENND1Achr9:126319848chr9:119188367ENST00000373620-1321300_378331560.0DomaindDENN
HgeneDENND1Achr9:126319848chr9:119188367ENST00000373624-1322300_3783311010.0DomaindDENN
HgeneDENND1Achr9:126319848chr9:119188367ENST00000394215-1220300_378301530.0DomaindDENN
HgeneDENND1Achr9:126319848chr9:119188367ENST00000394219-1121300_3782991021.0DomaindDENN
HgeneDENND1Achr9:126319848chr9:119188367ENST00000542603-11413_1450795.0DomainuDENN
HgeneDENND1Achr9:126319848chr9:119188367ENST00000542603-114162_2980795.0DomaincDENN
HgeneDENND1Achr9:126319848chr9:119188367ENST00000542603-114300_3780795.0DomaindDENN
HgeneDENND1Achr9:126319849chr9:119188367ENST00000373618-1219300_378299467.0DomaindDENN
HgeneDENND1Achr9:126319849chr9:119188367ENST00000373620-1321300_378331560.0DomaindDENN
HgeneDENND1Achr9:126319849chr9:119188367ENST00000373624-1322300_3783311010.0DomaindDENN
HgeneDENND1Achr9:126319849chr9:119188367ENST00000394215-1220300_378301530.0DomaindDENN
HgeneDENND1Achr9:126319849chr9:119188367ENST00000394219-1121300_3782991021.0DomaindDENN
HgeneDENND1Achr9:126319849chr9:119188367ENST00000542603-11413_1450795.0DomainuDENN
HgeneDENND1Achr9:126319849chr9:119188367ENST00000542603-114162_2980795.0DomaincDENN
HgeneDENND1Achr9:126319849chr9:119188367ENST00000542603-114300_3780795.0DomaindDENN
HgeneDENND1Achr9:126319848chr9:119188367ENST00000373618-1219381_385299467.0MotifFXDXF motif
HgeneDENND1Achr9:126319848chr9:119188367ENST00000373618-1219569_578299467.0MotifClathrin box
HgeneDENND1Achr9:126319848chr9:119188367ENST00000373620-1321381_385331560.0MotifFXDXF motif
HgeneDENND1Achr9:126319848chr9:119188367ENST00000373620-1321569_578331560.0MotifClathrin box
HgeneDENND1Achr9:126319848chr9:119188367ENST00000373624-1322381_3853311010.0MotifFXDXF motif
HgeneDENND1Achr9:126319848chr9:119188367ENST00000373624-1322569_5783311010.0MotifClathrin box
HgeneDENND1Achr9:126319848chr9:119188367ENST00000394215-1220381_385301530.0MotifFXDXF motif
HgeneDENND1Achr9:126319848chr9:119188367ENST00000394215-1220569_578301530.0MotifClathrin box
HgeneDENND1Achr9:126319848chr9:119188367ENST00000394219-1121381_3852991021.0MotifFXDXF motif
HgeneDENND1Achr9:126319848chr9:119188367ENST00000394219-1121569_5782991021.0MotifClathrin box
HgeneDENND1Achr9:126319848chr9:119188367ENST00000542603-114381_3850795.0MotifFXDXF motif
HgeneDENND1Achr9:126319848chr9:119188367ENST00000542603-114569_5780795.0MotifClathrin box
HgeneDENND1Achr9:126319849chr9:119188367ENST00000373618-1219381_385299467.0MotifFXDXF motif
HgeneDENND1Achr9:126319849chr9:119188367ENST00000373618-1219569_578299467.0MotifClathrin box
HgeneDENND1Achr9:126319849chr9:119188367ENST00000373620-1321381_385331560.0MotifFXDXF motif
HgeneDENND1Achr9:126319849chr9:119188367ENST00000373620-1321569_578331560.0MotifClathrin box
HgeneDENND1Achr9:126319849chr9:119188367ENST00000373624-1322381_3853311010.0MotifFXDXF motif
HgeneDENND1Achr9:126319849chr9:119188367ENST00000373624-1322569_5783311010.0MotifClathrin box
HgeneDENND1Achr9:126319849chr9:119188367ENST00000394215-1220381_385301530.0MotifFXDXF motif
HgeneDENND1Achr9:126319849chr9:119188367ENST00000394215-1220569_578301530.0MotifClathrin box
HgeneDENND1Achr9:126319849chr9:119188367ENST00000394219-1121381_3852991021.0MotifFXDXF motif
HgeneDENND1Achr9:126319849chr9:119188367ENST00000394219-1121569_5782991021.0MotifClathrin box
HgeneDENND1Achr9:126319849chr9:119188367ENST00000542603-114381_3850795.0MotifFXDXF motif
HgeneDENND1Achr9:126319849chr9:119188367ENST00000542603-114569_5780795.0MotifClathrin box
TgeneASTN2chr9:126319848chr9:119188367ENST0000031340021231065_118812601340.0DomainNote=Fibronectin type-III
TgeneASTN2chr9:126319848chr9:119188367ENST000003134002123510_55012601340.0DomainNote=EGF-like 1
TgeneASTN2chr9:126319848chr9:119188367ENST000003134002123651_69512601340.0DomainNote=EGF-like 2
TgeneASTN2chr9:126319848chr9:119188367ENST000003134002123699_75112601340.0DomainNote=EGF-like 3
TgeneASTN2chr9:126319848chr9:119188367ENST0000036120920221065_118812091289.0DomainNote=Fibronectin type-III
TgeneASTN2chr9:126319848chr9:119188367ENST000003612092022510_55012091289.0DomainNote=EGF-like 1
TgeneASTN2chr9:126319848chr9:119188367ENST000003612092022651_69512091289.0DomainNote=EGF-like 2
TgeneASTN2chr9:126319848chr9:119188367ENST000003612092022699_75112091289.0DomainNote=EGF-like 3
TgeneASTN2chr9:126319848chr9:119188367ENST0000037399621231065_118812561336.0DomainNote=Fibronectin type-III
TgeneASTN2chr9:126319848chr9:119188367ENST000003739962123510_55012561336.0DomainNote=EGF-like 1
TgeneASTN2chr9:126319848chr9:119188367ENST000003739962123651_69512561336.0DomainNote=EGF-like 2
TgeneASTN2chr9:126319848chr9:119188367ENST000003739962123699_75112561336.0DomainNote=EGF-like 3
TgeneASTN2chr9:126319849chr9:119188367ENST0000031340021231065_118812601340.0DomainNote=Fibronectin type-III
TgeneASTN2chr9:126319849chr9:119188367ENST000003134002123510_55012601340.0DomainNote=EGF-like 1
TgeneASTN2chr9:126319849chr9:119188367ENST000003134002123651_69512601340.0DomainNote=EGF-like 2
TgeneASTN2chr9:126319849chr9:119188367ENST000003134002123699_75112601340.0DomainNote=EGF-like 3
TgeneASTN2chr9:126319849chr9:119188367ENST0000036120920221065_118812091289.0DomainNote=Fibronectin type-III
TgeneASTN2chr9:126319849chr9:119188367ENST000003612092022510_55012091289.0DomainNote=EGF-like 1
TgeneASTN2chr9:126319849chr9:119188367ENST000003612092022651_69512091289.0DomainNote=EGF-like 2
TgeneASTN2chr9:126319849chr9:119188367ENST000003612092022699_75112091289.0DomainNote=EGF-like 3
TgeneASTN2chr9:126319849chr9:119188367ENST0000037399621231065_118812561336.0DomainNote=Fibronectin type-III
TgeneASTN2chr9:126319849chr9:119188367ENST000003739962123510_55012561336.0DomainNote=EGF-like 1
TgeneASTN2chr9:126319849chr9:119188367ENST000003739962123651_69512561336.0DomainNote=EGF-like 2
TgeneASTN2chr9:126319849chr9:119188367ENST000003739962123699_75112561336.0DomainNote=EGF-like 3
TgeneASTN2chr9:126319848chr9:119188367ENST0000028852068228_434361441.0Topological domainCytoplasmic
TgeneASTN2chr9:126319848chr9:119188367ENST000002885206850_206361441.0Topological domainLumenal
TgeneASTN2chr9:126319848chr9:119188367ENST000003134002123228_43412601340.0Topological domainCytoplasmic
TgeneASTN2chr9:126319848chr9:119188367ENST000003134002123456_133912601340.0Topological domainLumenal
TgeneASTN2chr9:126319848chr9:119188367ENST00000313400212350_20612601340.0Topological domainLumenal
TgeneASTN2chr9:126319848chr9:119188367ENST0000034173469228_434312396.0Topological domainCytoplasmic
TgeneASTN2chr9:126319848chr9:119188367ENST000003417346950_206312396.0Topological domainLumenal
TgeneASTN2chr9:126319848chr9:119188367ENST000003612092022228_43412091289.0Topological domainCytoplasmic
TgeneASTN2chr9:126319848chr9:119188367ENST000003612092022456_133912091289.0Topological domainLumenal
TgeneASTN2chr9:126319848chr9:119188367ENST00000361209202250_20612091289.0Topological domainLumenal
TgeneASTN2chr9:126319848chr9:119188367ENST000003614772023228_434312396.0Topological domainCytoplasmic
TgeneASTN2chr9:126319848chr9:119188367ENST00000361477202350_206312396.0Topological domainLumenal
TgeneASTN2chr9:126319848chr9:119188367ENST000003739962123228_43412561336.0Topological domainCytoplasmic
TgeneASTN2chr9:126319848chr9:119188367ENST000003739962123456_133912561336.0Topological domainLumenal
TgeneASTN2chr9:126319848chr9:119188367ENST00000373996212350_20612561336.0Topological domainLumenal
TgeneASTN2chr9:126319849chr9:119188367ENST0000028852068228_434361441.0Topological domainCytoplasmic
TgeneASTN2chr9:126319849chr9:119188367ENST000002885206850_206361441.0Topological domainLumenal
TgeneASTN2chr9:126319849chr9:119188367ENST000003134002123228_43412601340.0Topological domainCytoplasmic
TgeneASTN2chr9:126319849chr9:119188367ENST000003134002123456_133912601340.0Topological domainLumenal
TgeneASTN2chr9:126319849chr9:119188367ENST00000313400212350_20612601340.0Topological domainLumenal
TgeneASTN2chr9:126319849chr9:119188367ENST0000034173469228_434312396.0Topological domainCytoplasmic
TgeneASTN2chr9:126319849chr9:119188367ENST000003417346950_206312396.0Topological domainLumenal
TgeneASTN2chr9:126319849chr9:119188367ENST000003612092022228_43412091289.0Topological domainCytoplasmic
TgeneASTN2chr9:126319849chr9:119188367ENST000003612092022456_133912091289.0Topological domainLumenal
TgeneASTN2chr9:126319849chr9:119188367ENST00000361209202250_20612091289.0Topological domainLumenal
TgeneASTN2chr9:126319849chr9:119188367ENST000003614772023228_434312396.0Topological domainCytoplasmic
TgeneASTN2chr9:126319849chr9:119188367ENST00000361477202350_206312396.0Topological domainLumenal
TgeneASTN2chr9:126319849chr9:119188367ENST000003739962123228_43412561336.0Topological domainCytoplasmic
TgeneASTN2chr9:126319849chr9:119188367ENST000003739962123456_133912561336.0Topological domainLumenal
TgeneASTN2chr9:126319849chr9:119188367ENST00000373996212350_20612561336.0Topological domainLumenal
TgeneASTN2chr9:126319848chr9:119188367ENST0000028852068207_227361441.0TransmembraneHelical
TgeneASTN2chr9:126319848chr9:119188367ENST000003134002123207_22712601340.0TransmembraneHelical
TgeneASTN2chr9:126319848chr9:119188367ENST000003134002123435_45512601340.0TransmembraneHelical
TgeneASTN2chr9:126319848chr9:119188367ENST0000034173469207_227312396.0TransmembraneHelical
TgeneASTN2chr9:126319848chr9:119188367ENST000003612092022207_22712091289.0TransmembraneHelical
TgeneASTN2chr9:126319848chr9:119188367ENST000003612092022435_45512091289.0TransmembraneHelical
TgeneASTN2chr9:126319848chr9:119188367ENST000003614772023207_227312396.0TransmembraneHelical
TgeneASTN2chr9:126319848chr9:119188367ENST000003739962123207_22712561336.0TransmembraneHelical
TgeneASTN2chr9:126319848chr9:119188367ENST000003739962123435_45512561336.0TransmembraneHelical
TgeneASTN2chr9:126319849chr9:119188367ENST0000028852068207_227361441.0TransmembraneHelical
TgeneASTN2chr9:126319849chr9:119188367ENST000003134002123207_22712601340.0TransmembraneHelical
TgeneASTN2chr9:126319849chr9:119188367ENST000003134002123435_45512601340.0TransmembraneHelical
TgeneASTN2chr9:126319849chr9:119188367ENST0000034173469207_227312396.0TransmembraneHelical
TgeneASTN2chr9:126319849chr9:119188367ENST000003612092022207_22712091289.0TransmembraneHelical
TgeneASTN2chr9:126319849chr9:119188367ENST000003612092022435_45512091289.0TransmembraneHelical
TgeneASTN2chr9:126319849chr9:119188367ENST000003614772023207_227312396.0TransmembraneHelical
TgeneASTN2chr9:126319849chr9:119188367ENST000003739962123207_22712561336.0TransmembraneHelical
TgeneASTN2chr9:126319849chr9:119188367ENST000003739962123435_45512561336.0TransmembraneHelical


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Fusion Gene Sequence for DENND1A-ASTN2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>22190_22190_1_DENND1A-ASTN2_DENND1A_chr9_126319848_ENST00000373618_ASTN2_chr9_119188367_ENST00000288520_length(transcript)=2051nt_BP=1190nt
GGCGGAGGGGGCGGCGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCG
GCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTC
GGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAA
TCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCC
GGAGGACTACAGTGACCAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCG
GGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACA
TCCTGGCAGATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTCTGCACAAACTTCCCATCCCTGACCCAGGAG
TGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAAT
ATTTTGTGGCTGTGGATGTTAACAACATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCA
GCACTCTGACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATC
TGCTGGACTACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATG
TCGTGATCCTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCCTCCCAAACGACGTGATCTCTTCCCTGAAGA
ACAGGCTGAAAAAGGTCTCCACAACCACTGGGGATGGTGTGGCCAGAGCGTTCCTCAAGGCCCAGGCTGCTTTCTTCGGTAGCTACCGAA
ACGCTCTGAAAATCGAGCCGGAAGGCCCACCTGATTCTACGGCGACTGGAGAGGGTGAGTAGCCACTGCTCCAGCCTCCTGCGGAGTGCC
TACATCCAGAGCCGCGTGGAAACAGTGCCCTATCTTTTCTGCCGCAGCGAGGAGGTCCGGCCTGCAGGCATGGTGTGGTATAGCATCCTC
AAGGACACCAAAATCACGTGTGAGGAGAAGATGGTGTCAATGGCCCGAAACACGTACGGGGAGTCCAAGGGCCGGTGAGGGAGGGTATTG
CCCTCCGTGAGCACAGAGACTCTCCATGGGAGGGGGAGCAGTATTCTCCTGGATCCTGGGGCCTGGGTGGGCTGGGGGACAGCTGAGGAT
GGGCCTAGCAGATGAAGCTTGCCAGCAAGGCCAAAGCAAACGGTTTCTCCTGTGGATAGTGGACAGAGACCTTTGTAACCAATGGAATTA
TTCATTTTTCTCTATCTTTTATTTTTTCAAAGATATTATTTGACTCTATCAAAAGTCTCTCCTTTTTAAACCTTTTCTTATGGATGGCTG
TCAATCCCGAGGCAGAAGTTTTCAGGTGGAGACCAAGCGGCCTTTGCTCTTCTTCCTTCTTCCTGCCACACTCTGCTTTCTTCCTGCCAT
GGACCCCTGGAGGAGACCTATGGAGGGACAGTTTTGACCTGACCCCTAGAGGAGACAGTTTTGACCTCTTCAGCACCAGGAAGGAAGCTC
TGAGGATGGTTGCAGTGAGGAAGCATGGGTCTTTAAGGACTTCTCTCTCTTTTTTGCTGGACATTATTGAGTTTGTGGGACCCTGCCTCT

>22190_22190_1_DENND1A-ASTN2_DENND1A_chr9_126319848_ENST00000373618_ASTN2_chr9_119188367_ENST00000288520_length(amino acids)=366AA_BP=
MREGRKGRGERQREAGRPRAGGQRSAERGPRAHEEAWGPWAPGSSRIQRPHLKYMLKWPIPGQVALFQILRCRGNSRRTTVTSLTVSQVG
QNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVP
DTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIG
IHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEGPPDST

--------------------------------------------------------------
>22190_22190_2_DENND1A-ASTN2_DENND1A_chr9_126319848_ENST00000373618_ASTN2_chr9_119188367_ENST00000361209_length(transcript)=2051nt_BP=1190nt
GGCGGAGGGGGCGGCGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCG
GCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTC
GGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAA
TCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCC
GGAGGACTACAGTGACCAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCG
GGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACA
TCCTGGCAGATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTCTGCACAAACTTCCCATCCCTGACCCAGGAG
TGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAAT
ATTTTGTGGCTGTGGATGTTAACAACATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCA
GCACTCTGACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATC
TGCTGGACTACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATG
TCGTGATCCTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCCTCCCAAACGACGTGATCTCTTCCCTGAAGA
ACAGGCTGAAAAAGGTCTCCACAACCACTGGGGATGGTGTGGCCAGAGCGTTCCTCAAGGCCCAGGCTGCTTTCTTCGGTAGCTACCGAA
ACGCTCTGAAAATCGAGCCGGAAGGCCCACCTGATTCTACGGCGACTGGAGAGGGTGAGTAGCCACTGCTCCAGCCTCCTGCGGAGTGCC
TACATCCAGAGCCGCGTGGAAACAGTGCCCTATCTTTTCTGCCGCAGCGAGGAGGTCCGGCCTGCAGGCATGGTGTGGTATAGCATCCTC
AAGGACACCAAAATCACGTGTGAGGAGAAGATGGTGTCAATGGCCCGAAACACGTACGGGGAGTCCAAGGGCCGGTGAGGGAGGGTATTG
CCCTCCGTGAGCACAGAGACTCTCCATGGGAGGGGGAGCAGTATTCTCCTGGATCCTGGGGCCTGGGTGGGCTGGGGGACAGCTGAGGAT
GGGCCTAGCAGATGAAGCTTGCCAGCAAGGCCAAAGCAAACGGTTTCTCCTGTGGATAGTGGACAGAGACCTTTGTAACCAATGGAATTA
TTCATTTTTCTCTATCTTTTATTTTTTCAAAGATATTATTTGACTCTATCAAAAGTCTCTCCTTTTTAAACCTTTTCTTATGGATGGCTG
TCAATCCCGAGGCAGAAGTTTTCAGGTGGAGACCAAGCGGCCTTTGCTCTTCTTCCTTCTTCCTGCCACACTCTGCTTTCTTCCTGCCAT
GGACCCCTGGAGGAGACCTATGGAGGGACAGTTTTGACCTGACCCCTAGAGGAGACAGTTTTGACCTCTTCAGCACCAGGAAGGAAGCTC
TGAGGATGGTTGCAGTGAGGAAGCATGGGTCTTTAAGGACTTCTCTCTCTTTTTTGCTGGACATTATTGAGTTTGTGGGACCCTGCCTCT

>22190_22190_2_DENND1A-ASTN2_DENND1A_chr9_126319848_ENST00000373618_ASTN2_chr9_119188367_ENST00000361209_length(amino acids)=366AA_BP=
MREGRKGRGERQREAGRPRAGGQRSAERGPRAHEEAWGPWAPGSSRIQRPHLKYMLKWPIPGQVALFQILRCRGNSRRTTVTSLTVSQVG
QNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVP
DTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIG
IHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEGPPDST

--------------------------------------------------------------
>22190_22190_3_DENND1A-ASTN2_DENND1A_chr9_126319848_ENST00000373618_ASTN2_chr9_119188367_ENST00000373996_length(transcript)=2054nt_BP=1190nt
GGCGGAGGGGGCGGCGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCG
GCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTC
GGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAA
TCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCC
GGAGGACTACAGTGACCAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCG
GGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACA
TCCTGGCAGATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTCTGCACAAACTTCCCATCCCTGACCCAGGAG
TGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAAT
ATTTTGTGGCTGTGGATGTTAACAACATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCA
GCACTCTGACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATC
TGCTGGACTACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATG
TCGTGATCCTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCCTCCCAAACGACGTGATCTCTTCCCTGAAGA
ACAGGCTGAAAAAGGTCTCCACAACCACTGGGGATGGTGTGGCCAGAGCGTTCCTCAAGGCCCAGGCTGCTTTCTTCGGTAGCTACCGAA
ACGCTCTGAAAATCGAGCCGGAAGGCCCACCTGATTCTACGGCGACTGGAGAGGGTGAGTAGCCACTGCTCCAGCCTCCTGCGGAGTGCC
TACATCCAGAGCCGCGTGGAAACAGTGCCCTATCTTTTCTGCCGCAGCGAGGAGGTCCGGCCTGCAGGCATGGTGTGGTATAGCATCCTC
AAGGACACCAAAATCACGTGTGAGGAGAAGATGGTGTCAATGGCCCGAAACACGTACGGGGAGTCCAAGGGCCGGTGAGGGAGGGTATTG
CCCTCCGTGAGCACAGAGACTCTCCATGGGAGGGGGAGCAGTATTCTCCTGGATCCTGGGGCCTGGGTGGGCTGGGGGACAGCTGAGGAT
GGGCCTAGCAGATGAAGCTTGCCAGCAAGGCCAAAGCAAACGGTTTCTCCTGTGGATAGTGGACAGAGACCTTTGTAACCAATGGAATTA
TTCATTTTTCTCTATCTTTTATTTTTTCAAAGATATTATTTGACTCTATCAAAAGTCTCTCCTTTTTAAACCTTTTCTTATGGATGGCTG
TCAATCCCGAGGCAGAAGTTTTCAGGTGGAGACCAAGCGGCCTTTGCTCTTCTTCCTTCTTCCTGCCACACTCTGCTTTCTTCCTGCCAT
GGACCCCTGGAGGAGACCTATGGAGGGACAGTTTTGACCTGACCCCTAGAGGAGACAGTTTTGACCTCTTCAGCACCAGGAAGGAAGCTC
TGAGGATGGTTGCAGTGAGGAAGCATGGGTCTTTAAGGACTTCTCTCTCTTTTTTGCTGGACATTATTGAGTTTGTGGGACCCTGCCTCT

>22190_22190_3_DENND1A-ASTN2_DENND1A_chr9_126319848_ENST00000373618_ASTN2_chr9_119188367_ENST00000373996_length(amino acids)=366AA_BP=
MREGRKGRGERQREAGRPRAGGQRSAERGPRAHEEAWGPWAPGSSRIQRPHLKYMLKWPIPGQVALFQILRCRGNSRRTTVTSLTVSQVG
QNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVP
DTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIG
IHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEGPPDST

--------------------------------------------------------------
>22190_22190_4_DENND1A-ASTN2_DENND1A_chr9_126319848_ENST00000394215_ASTN2_chr9_119188367_ENST00000288520_length(transcript)=2043nt_BP=1182nt
CGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGA
GCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGC
GGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACAT
TTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTC
TATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGC
CGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCA
GATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTCTGCACAAACTTCCCATCCCTGACCCAGGAGTGTCTGTC
CATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAATATTTTGTG
GCTGTGGATGTTAACAACATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACTCTG
ACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATCTGCTGGAC
TACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATGTCGTGATC
CTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCCTCCCAAACGACGTGATCTCTTCCCTGAAGAACAGGCTG
AAAAAGGTCTCCACAACCACTGGGGATGGTGTGGCCAGAGCGTTCCTCAAGGCCCAGGCTGCTTTCTTCGGTAGCTACCGAAACGCTCTG
AAAATCGAGCCGGAAGGCCCACCTGATTCTACGGCGACTGGAGAGGGTGAGTAGCCACTGCTCCAGCCTCCTGCGGAGTGCCTACATCCA
GAGCCGCGTGGAAACAGTGCCCTATCTTTTCTGCCGCAGCGAGGAGGTCCGGCCTGCAGGCATGGTGTGGTATAGCATCCTCAAGGACAC
CAAAATCACGTGTGAGGAGAAGATGGTGTCAATGGCCCGAAACACGTACGGGGAGTCCAAGGGCCGGTGAGGGAGGGTATTGCCCTCCGT
GAGCACAGAGACTCTCCATGGGAGGGGGAGCAGTATTCTCCTGGATCCTGGGGCCTGGGTGGGCTGGGGGACAGCTGAGGATGGGCCTAG
CAGATGAAGCTTGCCAGCAAGGCCAAAGCAAACGGTTTCTCCTGTGGATAGTGGACAGAGACCTTTGTAACCAATGGAATTATTCATTTT
TCTCTATCTTTTATTTTTTCAAAGATATTATTTGACTCTATCAAAAGTCTCTCCTTTTTAAACCTTTTCTTATGGATGGCTGTCAATCCC
GAGGCAGAAGTTTTCAGGTGGAGACCAAGCGGCCTTTGCTCTTCTTCCTTCTTCCTGCCACACTCTGCTTTCTTCCTGCCATGGACCCCT
GGAGGAGACCTATGGAGGGACAGTTTTGACCTGACCCCTAGAGGAGACAGTTTTGACCTCTTCAGCACCAGGAAGGAAGCTCTGAGGATG
GTTGCAGTGAGGAAGCATGGGTCTTTAAGGACTTCTCTCTCTTTTTTGCTGGACATTATTGAGTTTGTGGGACCCTGCCTCTTCCTGCTA

>22190_22190_4_DENND1A-ASTN2_DENND1A_chr9_126319848_ENST00000394215_ASTN2_chr9_119188367_ENST00000288520_length(amino acids)=368AA_BP=
MREGRKGRGERQREAGRPRAGGQRSAERGPRAHEEAWGPWAPGSSRIQRPHLKYMLKWPIPGQVALFQEVLQTLTKFCFPFYVDSLTVSQ
VGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFT
VPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYL
IGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEGPPD

--------------------------------------------------------------
>22190_22190_5_DENND1A-ASTN2_DENND1A_chr9_126319848_ENST00000394215_ASTN2_chr9_119188367_ENST00000361209_length(transcript)=2043nt_BP=1182nt
CGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGA
GCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGC
GGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACAT
TTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTC
TATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGC
CGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCA
GATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTCTGCACAAACTTCCCATCCCTGACCCAGGAGTGTCTGTC
CATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAATATTTTGTG
GCTGTGGATGTTAACAACATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACTCTG
ACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATCTGCTGGAC
TACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATGTCGTGATC
CTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCCTCCCAAACGACGTGATCTCTTCCCTGAAGAACAGGCTG
AAAAAGGTCTCCACAACCACTGGGGATGGTGTGGCCAGAGCGTTCCTCAAGGCCCAGGCTGCTTTCTTCGGTAGCTACCGAAACGCTCTG
AAAATCGAGCCGGAAGGCCCACCTGATTCTACGGCGACTGGAGAGGGTGAGTAGCCACTGCTCCAGCCTCCTGCGGAGTGCCTACATCCA
GAGCCGCGTGGAAACAGTGCCCTATCTTTTCTGCCGCAGCGAGGAGGTCCGGCCTGCAGGCATGGTGTGGTATAGCATCCTCAAGGACAC
CAAAATCACGTGTGAGGAGAAGATGGTGTCAATGGCCCGAAACACGTACGGGGAGTCCAAGGGCCGGTGAGGGAGGGTATTGCCCTCCGT
GAGCACAGAGACTCTCCATGGGAGGGGGAGCAGTATTCTCCTGGATCCTGGGGCCTGGGTGGGCTGGGGGACAGCTGAGGATGGGCCTAG
CAGATGAAGCTTGCCAGCAAGGCCAAAGCAAACGGTTTCTCCTGTGGATAGTGGACAGAGACCTTTGTAACCAATGGAATTATTCATTTT
TCTCTATCTTTTATTTTTTCAAAGATATTATTTGACTCTATCAAAAGTCTCTCCTTTTTAAACCTTTTCTTATGGATGGCTGTCAATCCC
GAGGCAGAAGTTTTCAGGTGGAGACCAAGCGGCCTTTGCTCTTCTTCCTTCTTCCTGCCACACTCTGCTTTCTTCCTGCCATGGACCCCT
GGAGGAGACCTATGGAGGGACAGTTTTGACCTGACCCCTAGAGGAGACAGTTTTGACCTCTTCAGCACCAGGAAGGAAGCTCTGAGGATG
GTTGCAGTGAGGAAGCATGGGTCTTTAAGGACTTCTCTCTCTTTTTTGCTGGACATTATTGAGTTTGTGGGACCCTGCCTCTTCCTGCTA

>22190_22190_5_DENND1A-ASTN2_DENND1A_chr9_126319848_ENST00000394215_ASTN2_chr9_119188367_ENST00000361209_length(amino acids)=368AA_BP=
MREGRKGRGERQREAGRPRAGGQRSAERGPRAHEEAWGPWAPGSSRIQRPHLKYMLKWPIPGQVALFQEVLQTLTKFCFPFYVDSLTVSQ
VGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFT
VPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYL
IGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEGPPD

--------------------------------------------------------------
>22190_22190_6_DENND1A-ASTN2_DENND1A_chr9_126319848_ENST00000394215_ASTN2_chr9_119188367_ENST00000373996_length(transcript)=2046nt_BP=1182nt
CGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGA
GCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGC
GGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACAT
TTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTC
TATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGC
CGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCA
GATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTCTGCACAAACTTCCCATCCCTGACCCAGGAGTGTCTGTC
CATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAATATTTTGTG
GCTGTGGATGTTAACAACATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACTCTG
ACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATCTGCTGGAC
TACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATGTCGTGATC
CTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCCTCCCAAACGACGTGATCTCTTCCCTGAAGAACAGGCTG
AAAAAGGTCTCCACAACCACTGGGGATGGTGTGGCCAGAGCGTTCCTCAAGGCCCAGGCTGCTTTCTTCGGTAGCTACCGAAACGCTCTG
AAAATCGAGCCGGAAGGCCCACCTGATTCTACGGCGACTGGAGAGGGTGAGTAGCCACTGCTCCAGCCTCCTGCGGAGTGCCTACATCCA
GAGCCGCGTGGAAACAGTGCCCTATCTTTTCTGCCGCAGCGAGGAGGTCCGGCCTGCAGGCATGGTGTGGTATAGCATCCTCAAGGACAC
CAAAATCACGTGTGAGGAGAAGATGGTGTCAATGGCCCGAAACACGTACGGGGAGTCCAAGGGCCGGTGAGGGAGGGTATTGCCCTCCGT
GAGCACAGAGACTCTCCATGGGAGGGGGAGCAGTATTCTCCTGGATCCTGGGGCCTGGGTGGGCTGGGGGACAGCTGAGGATGGGCCTAG
CAGATGAAGCTTGCCAGCAAGGCCAAAGCAAACGGTTTCTCCTGTGGATAGTGGACAGAGACCTTTGTAACCAATGGAATTATTCATTTT
TCTCTATCTTTTATTTTTTCAAAGATATTATTTGACTCTATCAAAAGTCTCTCCTTTTTAAACCTTTTCTTATGGATGGCTGTCAATCCC
GAGGCAGAAGTTTTCAGGTGGAGACCAAGCGGCCTTTGCTCTTCTTCCTTCTTCCTGCCACACTCTGCTTTCTTCCTGCCATGGACCCCT
GGAGGAGACCTATGGAGGGACAGTTTTGACCTGACCCCTAGAGGAGACAGTTTTGACCTCTTCAGCACCAGGAAGGAAGCTCTGAGGATG
GTTGCAGTGAGGAAGCATGGGTCTTTAAGGACTTCTCTCTCTTTTTTGCTGGACATTATTGAGTTTGTGGGACCCTGCCTCTTCCTGCTA

>22190_22190_6_DENND1A-ASTN2_DENND1A_chr9_126319848_ENST00000394215_ASTN2_chr9_119188367_ENST00000373996_length(amino acids)=368AA_BP=
MREGRKGRGERQREAGRPRAGGQRSAERGPRAHEEAWGPWAPGSSRIQRPHLKYMLKWPIPGQVALFQEVLQTLTKFCFPFYVDSLTVSQ
VGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFT
VPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYL
IGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEGPPD

--------------------------------------------------------------
>22190_22190_7_DENND1A-ASTN2_DENND1A_chr9_126319849_ENST00000373618_ASTN2_chr9_119188367_ENST00000288520_length(transcript)=2051nt_BP=1190nt
GGCGGAGGGGGCGGCGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCG
GCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTC
GGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAA
TCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCC
GGAGGACTACAGTGACCAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCG
GGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACA
TCCTGGCAGATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTCTGCACAAACTTCCCATCCCTGACCCAGGAG
TGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAAT
ATTTTGTGGCTGTGGATGTTAACAACATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCA
GCACTCTGACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATC
TGCTGGACTACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATG
TCGTGATCCTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCCTCCCAAACGACGTGATCTCTTCCCTGAAGA
ACAGGCTGAAAAAGGTCTCCACAACCACTGGGGATGGTGTGGCCAGAGCGTTCCTCAAGGCCCAGGCTGCTTTCTTCGGTAGCTACCGAA
ACGCTCTGAAAATCGAGCCGGAAGGCCCACCTGATTCTACGGCGACTGGAGAGGGTGAGTAGCCACTGCTCCAGCCTCCTGCGGAGTGCC
TACATCCAGAGCCGCGTGGAAACAGTGCCCTATCTTTTCTGCCGCAGCGAGGAGGTCCGGCCTGCAGGCATGGTGTGGTATAGCATCCTC
AAGGACACCAAAATCACGTGTGAGGAGAAGATGGTGTCAATGGCCCGAAACACGTACGGGGAGTCCAAGGGCCGGTGAGGGAGGGTATTG
CCCTCCGTGAGCACAGAGACTCTCCATGGGAGGGGGAGCAGTATTCTCCTGGATCCTGGGGCCTGGGTGGGCTGGGGGACAGCTGAGGAT
GGGCCTAGCAGATGAAGCTTGCCAGCAAGGCCAAAGCAAACGGTTTCTCCTGTGGATAGTGGACAGAGACCTTTGTAACCAATGGAATTA
TTCATTTTTCTCTATCTTTTATTTTTTCAAAGATATTATTTGACTCTATCAAAAGTCTCTCCTTTTTAAACCTTTTCTTATGGATGGCTG
TCAATCCCGAGGCAGAAGTTTTCAGGTGGAGACCAAGCGGCCTTTGCTCTTCTTCCTTCTTCCTGCCACACTCTGCTTTCTTCCTGCCAT
GGACCCCTGGAGGAGACCTATGGAGGGACAGTTTTGACCTGACCCCTAGAGGAGACAGTTTTGACCTCTTCAGCACCAGGAAGGAAGCTC
TGAGGATGGTTGCAGTGAGGAAGCATGGGTCTTTAAGGACTTCTCTCTCTTTTTTGCTGGACATTATTGAGTTTGTGGGACCCTGCCTCT

>22190_22190_7_DENND1A-ASTN2_DENND1A_chr9_126319849_ENST00000373618_ASTN2_chr9_119188367_ENST00000288520_length(amino acids)=366AA_BP=
MREGRKGRGERQREAGRPRAGGQRSAERGPRAHEEAWGPWAPGSSRIQRPHLKYMLKWPIPGQVALFQILRCRGNSRRTTVTSLTVSQVG
QNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVP
DTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIG
IHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEGPPDST

--------------------------------------------------------------
>22190_22190_8_DENND1A-ASTN2_DENND1A_chr9_126319849_ENST00000373618_ASTN2_chr9_119188367_ENST00000361209_length(transcript)=2051nt_BP=1190nt
GGCGGAGGGGGCGGCGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCG
GCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTC
GGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAA
TCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCC
GGAGGACTACAGTGACCAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCG
GGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACA
TCCTGGCAGATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTCTGCACAAACTTCCCATCCCTGACCCAGGAG
TGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAAT
ATTTTGTGGCTGTGGATGTTAACAACATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCA
GCACTCTGACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATC
TGCTGGACTACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATG
TCGTGATCCTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCCTCCCAAACGACGTGATCTCTTCCCTGAAGA
ACAGGCTGAAAAAGGTCTCCACAACCACTGGGGATGGTGTGGCCAGAGCGTTCCTCAAGGCCCAGGCTGCTTTCTTCGGTAGCTACCGAA
ACGCTCTGAAAATCGAGCCGGAAGGCCCACCTGATTCTACGGCGACTGGAGAGGGTGAGTAGCCACTGCTCCAGCCTCCTGCGGAGTGCC
TACATCCAGAGCCGCGTGGAAACAGTGCCCTATCTTTTCTGCCGCAGCGAGGAGGTCCGGCCTGCAGGCATGGTGTGGTATAGCATCCTC
AAGGACACCAAAATCACGTGTGAGGAGAAGATGGTGTCAATGGCCCGAAACACGTACGGGGAGTCCAAGGGCCGGTGAGGGAGGGTATTG
CCCTCCGTGAGCACAGAGACTCTCCATGGGAGGGGGAGCAGTATTCTCCTGGATCCTGGGGCCTGGGTGGGCTGGGGGACAGCTGAGGAT
GGGCCTAGCAGATGAAGCTTGCCAGCAAGGCCAAAGCAAACGGTTTCTCCTGTGGATAGTGGACAGAGACCTTTGTAACCAATGGAATTA
TTCATTTTTCTCTATCTTTTATTTTTTCAAAGATATTATTTGACTCTATCAAAAGTCTCTCCTTTTTAAACCTTTTCTTATGGATGGCTG
TCAATCCCGAGGCAGAAGTTTTCAGGTGGAGACCAAGCGGCCTTTGCTCTTCTTCCTTCTTCCTGCCACACTCTGCTTTCTTCCTGCCAT
GGACCCCTGGAGGAGACCTATGGAGGGACAGTTTTGACCTGACCCCTAGAGGAGACAGTTTTGACCTCTTCAGCACCAGGAAGGAAGCTC
TGAGGATGGTTGCAGTGAGGAAGCATGGGTCTTTAAGGACTTCTCTCTCTTTTTTGCTGGACATTATTGAGTTTGTGGGACCCTGCCTCT

>22190_22190_8_DENND1A-ASTN2_DENND1A_chr9_126319849_ENST00000373618_ASTN2_chr9_119188367_ENST00000361209_length(amino acids)=366AA_BP=
MREGRKGRGERQREAGRPRAGGQRSAERGPRAHEEAWGPWAPGSSRIQRPHLKYMLKWPIPGQVALFQILRCRGNSRRTTVTSLTVSQVG
QNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVP
DTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIG
IHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEGPPDST

--------------------------------------------------------------
>22190_22190_9_DENND1A-ASTN2_DENND1A_chr9_126319849_ENST00000373618_ASTN2_chr9_119188367_ENST00000373996_length(transcript)=2054nt_BP=1190nt
GGCGGAGGGGGCGGCGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCG
GCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTC
GGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAA
TCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCC
GGAGGACTACAGTGACCAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCG
GGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACA
TCCTGGCAGATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTCTGCACAAACTTCCCATCCCTGACCCAGGAG
TGTCTGTCCATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAAT
ATTTTGTGGCTGTGGATGTTAACAACATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCA
GCACTCTGACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATC
TGCTGGACTACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATG
TCGTGATCCTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCCTCCCAAACGACGTGATCTCTTCCCTGAAGA
ACAGGCTGAAAAAGGTCTCCACAACCACTGGGGATGGTGTGGCCAGAGCGTTCCTCAAGGCCCAGGCTGCTTTCTTCGGTAGCTACCGAA
ACGCTCTGAAAATCGAGCCGGAAGGCCCACCTGATTCTACGGCGACTGGAGAGGGTGAGTAGCCACTGCTCCAGCCTCCTGCGGAGTGCC
TACATCCAGAGCCGCGTGGAAACAGTGCCCTATCTTTTCTGCCGCAGCGAGGAGGTCCGGCCTGCAGGCATGGTGTGGTATAGCATCCTC
AAGGACACCAAAATCACGTGTGAGGAGAAGATGGTGTCAATGGCCCGAAACACGTACGGGGAGTCCAAGGGCCGGTGAGGGAGGGTATTG
CCCTCCGTGAGCACAGAGACTCTCCATGGGAGGGGGAGCAGTATTCTCCTGGATCCTGGGGCCTGGGTGGGCTGGGGGACAGCTGAGGAT
GGGCCTAGCAGATGAAGCTTGCCAGCAAGGCCAAAGCAAACGGTTTCTCCTGTGGATAGTGGACAGAGACCTTTGTAACCAATGGAATTA
TTCATTTTTCTCTATCTTTTATTTTTTCAAAGATATTATTTGACTCTATCAAAAGTCTCTCCTTTTTAAACCTTTTCTTATGGATGGCTG
TCAATCCCGAGGCAGAAGTTTTCAGGTGGAGACCAAGCGGCCTTTGCTCTTCTTCCTTCTTCCTGCCACACTCTGCTTTCTTCCTGCCAT
GGACCCCTGGAGGAGACCTATGGAGGGACAGTTTTGACCTGACCCCTAGAGGAGACAGTTTTGACCTCTTCAGCACCAGGAAGGAAGCTC
TGAGGATGGTTGCAGTGAGGAAGCATGGGTCTTTAAGGACTTCTCTCTCTTTTTTGCTGGACATTATTGAGTTTGTGGGACCCTGCCTCT

>22190_22190_9_DENND1A-ASTN2_DENND1A_chr9_126319849_ENST00000373618_ASTN2_chr9_119188367_ENST00000373996_length(amino acids)=366AA_BP=
MREGRKGRGERQREAGRPRAGGQRSAERGPRAHEEAWGPWAPGSSRIQRPHLKYMLKWPIPGQVALFQILRCRGNSRRTTVTSLTVSQVG
QNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVP
DTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIG
IHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEGPPDST

--------------------------------------------------------------
>22190_22190_10_DENND1A-ASTN2_DENND1A_chr9_126319849_ENST00000394215_ASTN2_chr9_119188367_ENST00000288520_length(transcript)=2043nt_BP=1182nt
CGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGA
GCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGC
GGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACAT
TTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTC
TATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGC
CGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCA
GATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTCTGCACAAACTTCCCATCCCTGACCCAGGAGTGTCTGTC
CATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAATATTTTGTG
GCTGTGGATGTTAACAACATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACTCTG
ACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATCTGCTGGAC
TACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATGTCGTGATC
CTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCCTCCCAAACGACGTGATCTCTTCCCTGAAGAACAGGCTG
AAAAAGGTCTCCACAACCACTGGGGATGGTGTGGCCAGAGCGTTCCTCAAGGCCCAGGCTGCTTTCTTCGGTAGCTACCGAAACGCTCTG
AAAATCGAGCCGGAAGGCCCACCTGATTCTACGGCGACTGGAGAGGGTGAGTAGCCACTGCTCCAGCCTCCTGCGGAGTGCCTACATCCA
GAGCCGCGTGGAAACAGTGCCCTATCTTTTCTGCCGCAGCGAGGAGGTCCGGCCTGCAGGCATGGTGTGGTATAGCATCCTCAAGGACAC
CAAAATCACGTGTGAGGAGAAGATGGTGTCAATGGCCCGAAACACGTACGGGGAGTCCAAGGGCCGGTGAGGGAGGGTATTGCCCTCCGT
GAGCACAGAGACTCTCCATGGGAGGGGGAGCAGTATTCTCCTGGATCCTGGGGCCTGGGTGGGCTGGGGGACAGCTGAGGATGGGCCTAG
CAGATGAAGCTTGCCAGCAAGGCCAAAGCAAACGGTTTCTCCTGTGGATAGTGGACAGAGACCTTTGTAACCAATGGAATTATTCATTTT
TCTCTATCTTTTATTTTTTCAAAGATATTATTTGACTCTATCAAAAGTCTCTCCTTTTTAAACCTTTTCTTATGGATGGCTGTCAATCCC
GAGGCAGAAGTTTTCAGGTGGAGACCAAGCGGCCTTTGCTCTTCTTCCTTCTTCCTGCCACACTCTGCTTTCTTCCTGCCATGGACCCCT
GGAGGAGACCTATGGAGGGACAGTTTTGACCTGACCCCTAGAGGAGACAGTTTTGACCTCTTCAGCACCAGGAAGGAAGCTCTGAGGATG
GTTGCAGTGAGGAAGCATGGGTCTTTAAGGACTTCTCTCTCTTTTTTGCTGGACATTATTGAGTTTGTGGGACCCTGCCTCTTCCTGCTA

>22190_22190_10_DENND1A-ASTN2_DENND1A_chr9_126319849_ENST00000394215_ASTN2_chr9_119188367_ENST00000288520_length(amino acids)=368AA_BP=
MREGRKGRGERQREAGRPRAGGQRSAERGPRAHEEAWGPWAPGSSRIQRPHLKYMLKWPIPGQVALFQEVLQTLTKFCFPFYVDSLTVSQ
VGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFT
VPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYL
IGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEGPPD

--------------------------------------------------------------
>22190_22190_11_DENND1A-ASTN2_DENND1A_chr9_126319849_ENST00000394215_ASTN2_chr9_119188367_ENST00000361209_length(transcript)=2043nt_BP=1182nt
CGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGA
GCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGC
GGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACAT
TTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTC
TATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGC
CGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCA
GATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTCTGCACAAACTTCCCATCCCTGACCCAGGAGTGTCTGTC
CATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAATATTTTGTG
GCTGTGGATGTTAACAACATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACTCTG
ACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATCTGCTGGAC
TACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATGTCGTGATC
CTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCCTCCCAAACGACGTGATCTCTTCCCTGAAGAACAGGCTG
AAAAAGGTCTCCACAACCACTGGGGATGGTGTGGCCAGAGCGTTCCTCAAGGCCCAGGCTGCTTTCTTCGGTAGCTACCGAAACGCTCTG
AAAATCGAGCCGGAAGGCCCACCTGATTCTACGGCGACTGGAGAGGGTGAGTAGCCACTGCTCCAGCCTCCTGCGGAGTGCCTACATCCA
GAGCCGCGTGGAAACAGTGCCCTATCTTTTCTGCCGCAGCGAGGAGGTCCGGCCTGCAGGCATGGTGTGGTATAGCATCCTCAAGGACAC
CAAAATCACGTGTGAGGAGAAGATGGTGTCAATGGCCCGAAACACGTACGGGGAGTCCAAGGGCCGGTGAGGGAGGGTATTGCCCTCCGT
GAGCACAGAGACTCTCCATGGGAGGGGGAGCAGTATTCTCCTGGATCCTGGGGCCTGGGTGGGCTGGGGGACAGCTGAGGATGGGCCTAG
CAGATGAAGCTTGCCAGCAAGGCCAAAGCAAACGGTTTCTCCTGTGGATAGTGGACAGAGACCTTTGTAACCAATGGAATTATTCATTTT
TCTCTATCTTTTATTTTTTCAAAGATATTATTTGACTCTATCAAAAGTCTCTCCTTTTTAAACCTTTTCTTATGGATGGCTGTCAATCCC
GAGGCAGAAGTTTTCAGGTGGAGACCAAGCGGCCTTTGCTCTTCTTCCTTCTTCCTGCCACACTCTGCTTTCTTCCTGCCATGGACCCCT
GGAGGAGACCTATGGAGGGACAGTTTTGACCTGACCCCTAGAGGAGACAGTTTTGACCTCTTCAGCACCAGGAAGGAAGCTCTGAGGATG
GTTGCAGTGAGGAAGCATGGGTCTTTAAGGACTTCTCTCTCTTTTTTGCTGGACATTATTGAGTTTGTGGGACCCTGCCTCTTCCTGCTA

>22190_22190_11_DENND1A-ASTN2_DENND1A_chr9_126319849_ENST00000394215_ASTN2_chr9_119188367_ENST00000361209_length(amino acids)=368AA_BP=
MREGRKGRGERQREAGRPRAGGQRSAERGPRAHEEAWGPWAPGSSRIQRPHLKYMLKWPIPGQVALFQEVLQTLTKFCFPFYVDSLTVSQ
VGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFT
VPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYL
IGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEGPPD

--------------------------------------------------------------
>22190_22190_12_DENND1A-ASTN2_DENND1A_chr9_126319849_ENST00000394215_ASTN2_chr9_119188367_ENST00000373996_length(transcript)=2046nt_BP=1182nt
CGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGA
GCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGC
GGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACAT
TTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTC
TATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGC
CGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGCTATCTCCCCTGGTTCGAGGTATTTTATAAGCTGCTTAACATCCTGGCA
GATTACACGACAAAAAGACAGGAAAATCAGTGGAATGAGCTTCTTGAAACTCTGCACAAACTTCCCATCCCTGACCCAGGAGTGTCTGTC
CATCTCAGCGTGCATTCTTATTTTACTGTGCCTGATACCAGAGAACTTCCCAGCATACCTGAGAATAGAAATCTGACAGAATATTTTGTG
GCTGTGGATGTTAACAACATGTTGCATCTGTACGCCAGTATGCTGTACGAACGCCGGATACTCATCATTTGCAGCAAACTCAGCACTCTG
ACTGCCTGCATCCACGGGTCTGCGGCGATGCTCTACCCCATGTACTGGCAGCACGTGTACATCCCCGTGCTGCCGCCGCATCTGCTGGAC
TACTGCTGTGCTCCCATGCCCTACCTCATAGGAATCCATTTAAGTTTAATGGAGAAAGTCAGAAACATGGCCCTGGATGATGTCGTGATC
CTGAATGTGGACACCAACACCCTGGAAACCCCCTTCGATGACCTCCAGAGCCTCCCAAACGACGTGATCTCTTCCCTGAAGAACAGGCTG
AAAAAGGTCTCCACAACCACTGGGGATGGTGTGGCCAGAGCGTTCCTCAAGGCCCAGGCTGCTTTCTTCGGTAGCTACCGAAACGCTCTG
AAAATCGAGCCGGAAGGCCCACCTGATTCTACGGCGACTGGAGAGGGTGAGTAGCCACTGCTCCAGCCTCCTGCGGAGTGCCTACATCCA
GAGCCGCGTGGAAACAGTGCCCTATCTTTTCTGCCGCAGCGAGGAGGTCCGGCCTGCAGGCATGGTGTGGTATAGCATCCTCAAGGACAC
CAAAATCACGTGTGAGGAGAAGATGGTGTCAATGGCCCGAAACACGTACGGGGAGTCCAAGGGCCGGTGAGGGAGGGTATTGCCCTCCGT
GAGCACAGAGACTCTCCATGGGAGGGGGAGCAGTATTCTCCTGGATCCTGGGGCCTGGGTGGGCTGGGGGACAGCTGAGGATGGGCCTAG
CAGATGAAGCTTGCCAGCAAGGCCAAAGCAAACGGTTTCTCCTGTGGATAGTGGACAGAGACCTTTGTAACCAATGGAATTATTCATTTT
TCTCTATCTTTTATTTTTTCAAAGATATTATTTGACTCTATCAAAAGTCTCTCCTTTTTAAACCTTTTCTTATGGATGGCTGTCAATCCC
GAGGCAGAAGTTTTCAGGTGGAGACCAAGCGGCCTTTGCTCTTCTTCCTTCTTCCTGCCACACTCTGCTTTCTTCCTGCCATGGACCCCT
GGAGGAGACCTATGGAGGGACAGTTTTGACCTGACCCCTAGAGGAGACAGTTTTGACCTCTTCAGCACCAGGAAGGAAGCTCTGAGGATG
GTTGCAGTGAGGAAGCATGGGTCTTTAAGGACTTCTCTCTCTTTTTTGCTGGACATTATTGAGTTTGTGGGACCCTGCCTCTTCCTGCTA

>22190_22190_12_DENND1A-ASTN2_DENND1A_chr9_126319849_ENST00000394215_ASTN2_chr9_119188367_ENST00000373996_length(amino acids)=368AA_BP=
MREGRKGRGERQREAGRPRAGGQRSAERGPRAHEEAWGPWAPGSSRIQRPHLKYMLKWPIPGQVALFQEVLQTLTKFCFPFYVDSLTVSQ
VGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFT
VPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYL
IGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEGPPD

--------------------------------------------------------------

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Fusion Gene PPI Analysis for DENND1A-ASTN2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DENND1A-ASTN2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DENND1A-ASTN2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource