FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:DENND1A-LRRC69 (FusionGDB2 ID:22198)

Fusion Gene Summary for DENND1A-LRRC69

check button Fusion gene summary
Fusion gene informationFusion gene name: DENND1A-LRRC69
Fusion gene ID: 22198
HgeneTgene
Gene symbol

DENND1A

LRRC69

Gene ID

57706

100130742

Gene nameDENN domain containing 1Aleucine rich repeat containing 69
SynonymsFAM31A|KIAA1608-
Cytomap

9q33.3

8q21.3

Type of geneprotein-codingprotein-coding
DescriptionDENN domain-containing protein 1ADENN/MADD domain containing 1Aconnecdenn 1leucine-rich repeat-containing protein 69
Modification date2020032020200313
UniProtAcc

Q8TEH3

Q6ZNQ3

Ensembl transtripts involved in fusion geneENST00000373618, ENST00000373620, 
ENST00000373624, ENST00000394215, 
ENST00000394219, ENST00000473039, 
ENST00000542603, 		ENST00000343709, 
ENST00000448384, ENST00000521519, 
Fusion gene scores* DoF score18 X 18 X 14=45364 X 7 X 3=84
# samples 265
** MAII scorelog2(26/4536*10)=-4.12483711191377
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/84*10)=-0.748461233004036
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DENND1A [Title/Abstract] AND LRRC69 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDENND1A(126519982)-LRRC69(92231118), # samples:3
Anticipated loss of major functional domain due to fusion event.DENND1A-LRRC69 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneDENND1A

GO:0032483

regulation of Rab protein signal transduction

20937701


check buttonFusion gene breakpoints across DENND1A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across LRRC69 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A2-A0T1-01ADENND1Achr9

126519982

-LRRC69chr8

92136721

+
ChimerDB4BRCATCGA-A2-A0T1-01ADENND1Achr9

126519982

-LRRC69chr8

92201750

+
ChimerDB4BRCATCGA-A2-A0T1-01ADENND1Achr9

126519982

-LRRC69chr8

92231118

+
ChimerDB4BRCATCGA-A2-A0T1DENND1Achr9

126519981

-LRRC69chr8

92231117

+


Top

Fusion Gene ORF analysis for DENND1A-LRRC69

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000373618ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92136721

+
5CDS-intronENST00000373618ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92136721

+
5CDS-intronENST00000373618ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92136721

+
5CDS-intronENST00000373618ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92201750

+
5CDS-intronENST00000373618ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92231118

+
5CDS-intronENST00000373618ENST00000521519DENND1Achr9

126519981

-LRRC69chr8

92231117

+
5CDS-intronENST00000373620ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92136721

+
5CDS-intronENST00000373620ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92136721

+
5CDS-intronENST00000373620ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92136721

+
5CDS-intronENST00000373620ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92201750

+
5CDS-intronENST00000373620ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92231118

+
5CDS-intronENST00000373620ENST00000521519DENND1Achr9

126519981

-LRRC69chr8

92231117

+
5CDS-intronENST00000373624ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92136721

+
5CDS-intronENST00000373624ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92136721

+
5CDS-intronENST00000373624ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92136721

+
5CDS-intronENST00000373624ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92201750

+
5CDS-intronENST00000373624ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92231118

+
5CDS-intronENST00000373624ENST00000521519DENND1Achr9

126519981

-LRRC69chr8

92231117

+
5CDS-intronENST00000394215ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92136721

+
5CDS-intronENST00000394215ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92136721

+
5CDS-intronENST00000394215ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92136721

+
5CDS-intronENST00000394215ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92201750

+
5CDS-intronENST00000394215ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92231118

+
5CDS-intronENST00000394215ENST00000521519DENND1Achr9

126519981

-LRRC69chr8

92231117

+
5CDS-intronENST00000394219ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92136721

+
5CDS-intronENST00000394219ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92136721

+
5CDS-intronENST00000394219ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92136721

+
5CDS-intronENST00000394219ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92201750

+
5CDS-intronENST00000394219ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92231118

+
5CDS-intronENST00000394219ENST00000521519DENND1Achr9

126519981

-LRRC69chr8

92231117

+
5UTR-3CDSENST00000473039ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92201750

+
5UTR-3CDSENST00000473039ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92231118

+
5UTR-3CDSENST00000473039ENST00000343709DENND1Achr9

126519981

-LRRC69chr8

92231117

+
5UTR-3CDSENST00000473039ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92201750

+
5UTR-3CDSENST00000473039ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92231118

+
5UTR-3CDSENST00000473039ENST00000448384DENND1Achr9

126519981

-LRRC69chr8

92231117

+
5UTR-intronENST00000473039ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92136721

+
5UTR-intronENST00000473039ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92136721

+
5UTR-intronENST00000473039ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92136721

+
5UTR-intronENST00000473039ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92201750

+
5UTR-intronENST00000473039ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92231118

+
5UTR-intronENST00000473039ENST00000521519DENND1Achr9

126519981

-LRRC69chr8

92231117

+
Frame-shiftENST00000373618ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92231118

+
Frame-shiftENST00000373618ENST00000343709DENND1Achr9

126519981

-LRRC69chr8

92231117

+
Frame-shiftENST00000373620ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92201750

+
Frame-shiftENST00000373620ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92201750

+
Frame-shiftENST00000373620ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92231118

+
Frame-shiftENST00000373620ENST00000448384DENND1Achr9

126519981

-LRRC69chr8

92231117

+
Frame-shiftENST00000373624ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92201750

+
Frame-shiftENST00000373624ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92201750

+
Frame-shiftENST00000373624ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92231118

+
Frame-shiftENST00000373624ENST00000448384DENND1Achr9

126519981

-LRRC69chr8

92231117

+
Frame-shiftENST00000394215ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92231118

+
Frame-shiftENST00000394215ENST00000343709DENND1Achr9

126519981

-LRRC69chr8

92231117

+
Frame-shiftENST00000394219ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92201750

+
Frame-shiftENST00000394219ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92201750

+
Frame-shiftENST00000394219ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92231118

+
Frame-shiftENST00000394219ENST00000448384DENND1Achr9

126519981

-LRRC69chr8

92231117

+
In-frameENST00000373618ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92201750

+
In-frameENST00000373618ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92201750

+
In-frameENST00000373618ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92231118

+
In-frameENST00000373618ENST00000448384DENND1Achr9

126519981

-LRRC69chr8

92231117

+
In-frameENST00000373620ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92231118

+
In-frameENST00000373620ENST00000343709DENND1Achr9

126519981

-LRRC69chr8

92231117

+
In-frameENST00000373624ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92231118

+
In-frameENST00000373624ENST00000343709DENND1Achr9

126519981

-LRRC69chr8

92231117

+
In-frameENST00000394215ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92201750

+
In-frameENST00000394215ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92201750

+
In-frameENST00000394215ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92231118

+
In-frameENST00000394215ENST00000448384DENND1Achr9

126519981

-LRRC69chr8

92231117

+
In-frameENST00000394219ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92231118

+
In-frameENST00000394219ENST00000343709DENND1Achr9

126519981

-LRRC69chr8

92231117

+
intron-3CDSENST00000542603ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92201750

+
intron-3CDSENST00000542603ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92231118

+
intron-3CDSENST00000542603ENST00000343709DENND1Achr9

126519981

-LRRC69chr8

92231117

+
intron-3CDSENST00000542603ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92201750

+
intron-3CDSENST00000542603ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92231118

+
intron-3CDSENST00000542603ENST00000448384DENND1Achr9

126519981

-LRRC69chr8

92231117

+
intron-intronENST00000542603ENST00000343709DENND1Achr9

126519982

-LRRC69chr8

92136721

+
intron-intronENST00000542603ENST00000448384DENND1Achr9

126519982

-LRRC69chr8

92136721

+
intron-intronENST00000542603ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92136721

+
intron-intronENST00000542603ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92201750

+
intron-intronENST00000542603ENST00000521519DENND1Achr9

126519982

-LRRC69chr8

92231118

+
intron-intronENST00000542603ENST00000521519DENND1Achr9

126519981

-LRRC69chr8

92231117

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000373624DENND1Achr9126519982-ENST00000343709LRRC69chr892231118+742504193516107
ENST00000394219DENND1Achr9126519982-ENST00000343709LRRC69chr892231118+634396225175
ENST00000373620DENND1Achr9126519982-ENST00000343709LRRC69chr892231118+761523212535107
ENST00000394215DENND1Achr9126519982-ENST00000448384LRRC69chr892231118+602491117503128
ENST00000373618DENND1Achr9126519982-ENST00000448384LRRC69chr892231118+610499131511126
ENST00000373624DENND1Achr9126519981-ENST00000343709LRRC69chr892231117+742504193516107
ENST00000394219DENND1Achr9126519981-ENST00000343709LRRC69chr892231117+634396225175
ENST00000373620DENND1Achr9126519981-ENST00000343709LRRC69chr892231117+761523212535107
ENST00000394215DENND1Achr9126519981-ENST00000448384LRRC69chr892231117+602491117503128
ENST00000373618DENND1Achr9126519981-ENST00000448384LRRC69chr892231117+610499131511126
ENST00000394215DENND1Achr9126519982-ENST00000343709LRRC69chr892201750+1011491446883145
ENST00000394215DENND1Achr9126519982-ENST00000448384LRRC69chr892201750+884491446883146
ENST00000373618DENND1Achr9126519982-ENST00000343709LRRC69chr892201750+1019499454891145
ENST00000373618DENND1Achr9126519982-ENST00000448384LRRC69chr892201750+892499454891146

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000373624ENST00000343709DENND1Achr9126519982-LRRC69chr892231118+0.16514290.83485717
ENST00000394219ENST00000343709DENND1Achr9126519982-LRRC69chr892231118+0.73810910.2618909
ENST00000373620ENST00000343709DENND1Achr9126519982-LRRC69chr892231118+0.135287030.86471295
ENST00000394215ENST00000448384DENND1Achr9126519982-LRRC69chr892231118+0.657838050.34216195
ENST00000373618ENST00000448384DENND1Achr9126519982-LRRC69chr892231118+0.63906840.36093152
ENST00000373624ENST00000343709DENND1Achr9126519981-LRRC69chr892231117+0.16514290.83485717
ENST00000394219ENST00000343709DENND1Achr9126519981-LRRC69chr892231117+0.73810910.2618909
ENST00000373620ENST00000343709DENND1Achr9126519981-LRRC69chr892231117+0.135287030.86471295
ENST00000394215ENST00000448384DENND1Achr9126519981-LRRC69chr892231117+0.657838050.34216195
ENST00000373618ENST00000448384DENND1Achr9126519981-LRRC69chr892231117+0.63906840.36093152
ENST00000394215ENST00000343709DENND1Achr9126519982-LRRC69chr892201750+0.55039430.4496057
ENST00000394215ENST00000448384DENND1Achr9126519982-LRRC69chr892201750+0.492640850.50735915
ENST00000373618ENST00000343709DENND1Achr9126519982-LRRC69chr892201750+0.335242150.66475785
ENST00000373618ENST00000448384DENND1Achr9126519982-LRRC69chr892201750+0.269050540.7309494

Top

Fusion Genomic Features for DENND1A-LRRC69


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DENND1Achr9126519981-LRRC69chr892136720+0.0005987070.99940133
DENND1Achr9126519981-LRRC69chr892231117+1.62E-050.9999838
DENND1Achr9126519981-LRRC69chr892231117+1.62E-050.9999838
DENND1Achr9126519981-LRRC69chr892201749+2.42E-070.99999976
DENND1Achr9126519981-LRRC69chr892136720+0.0005987070.99940133
DENND1Achr9126519981-LRRC69chr892231117+1.62E-050.9999838
DENND1Achr9126519981-LRRC69chr892231117+1.62E-050.9999838
DENND1Achr9126519981-LRRC69chr892201749+2.42E-070.99999976

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for DENND1A-LRRC69


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:126519982/chr8:92231118)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DENND1A

Q8TEH3

LRRC69

Q6ZNQ3

FUNCTION: Guanine nucleotide exchange factor (GEF) regulating clathrin-mediated endocytosis through RAB35 activation. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB35 into its active GTP-bound form. Regulates clathrin-mediated endocytosis of synaptic vesicles and mediates exit from early endosomes (PubMed:20154091, PubMed:20937701). Binds phosphatidylinositol-phosphates (PtdInsPs), with some preference for PtdIns(3)P (By similarity). {ECO:0000250|UniProtKB:Q8K382, ECO:0000269|PubMed:20154091, ECO:0000269|PubMed:20937701}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneLRRC69chr9:126519981chr8:92231117ENST0000034370924154_175155192.0RepeatNote=LRR 6
TgeneLRRC69chr9:126519981chr8:92231117ENST0000034370924177_199155192.0RepeatNote=LRR 7
TgeneLRRC69chr9:126519981chr8:92231117ENST0000034370924200_222155192.0RepeatNote=LRR 8
TgeneLRRC69chr9:126519982chr8:92201750ENST0000034370904108_12961192.0RepeatNote=LRR 4
TgeneLRRC69chr9:126519982chr8:92201750ENST0000034370904131_15361192.0RepeatNote=LRR 5
TgeneLRRC69chr9:126519982chr8:92201750ENST0000034370904154_17561192.0RepeatNote=LRR 6
TgeneLRRC69chr9:126519982chr8:92201750ENST0000034370904177_19961192.0RepeatNote=LRR 7
TgeneLRRC69chr9:126519982chr8:92201750ENST0000034370904200_22261192.0RepeatNote=LRR 8
TgeneLRRC69chr9:126519982chr8:92201750ENST000003437090461_8261192.0RepeatNote=LRR 2
TgeneLRRC69chr9:126519982chr8:92201750ENST000003437090484_10561192.0RepeatNote=LRR 3
TgeneLRRC69chr9:126519982chr8:92231118ENST0000034370924154_175155192.0RepeatNote=LRR 6
TgeneLRRC69chr9:126519982chr8:92231118ENST0000034370924177_199155192.0RepeatNote=LRR 7
TgeneLRRC69chr9:126519982chr8:92231118ENST0000034370924200_222155192.0RepeatNote=LRR 8

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDENND1Achr9:126519981chr8:92231117ENST00000373618-419649_99568467.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126519981chr8:92231117ENST00000373620-521649_995100560.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126519981chr8:92231117ENST00000373624-522649_9951001010.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126519981chr8:92231117ENST00000394215-420649_99570530.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126519981chr8:92231117ENST00000394219-321649_995681021.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126519981chr8:92231117ENST00000542603-114649_9950795.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126519982chr8:92201750ENST00000373618-419649_99568467.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126519982chr8:92201750ENST00000373620-521649_995100560.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126519982chr8:92201750ENST00000373624-522649_9951001010.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126519982chr8:92201750ENST00000394215-420649_99570530.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126519982chr8:92201750ENST00000394219-321649_995681021.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126519982chr8:92201750ENST00000542603-114649_9950795.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126519982chr8:92231118ENST00000373618-419649_99568467.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126519982chr8:92231118ENST00000373620-521649_995100560.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126519982chr8:92231118ENST00000373624-522649_9951001010.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126519982chr8:92231118ENST00000394215-420649_99570530.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126519982chr8:92231118ENST00000394219-321649_995681021.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126519982chr8:92231118ENST00000542603-114649_9950795.0Compositional biasNote=Pro-rich
HgeneDENND1Achr9:126519981chr8:92231117ENST00000373618-41913_14568467.0DomainuDENN
HgeneDENND1Achr9:126519981chr8:92231117ENST00000373618-419162_29868467.0DomaincDENN
HgeneDENND1Achr9:126519981chr8:92231117ENST00000373618-419300_37868467.0DomaindDENN
HgeneDENND1Achr9:126519981chr8:92231117ENST00000373620-52113_145100560.0DomainuDENN
HgeneDENND1Achr9:126519981chr8:92231117ENST00000373620-521162_298100560.0DomaincDENN
HgeneDENND1Achr9:126519981chr8:92231117ENST00000373620-521300_378100560.0DomaindDENN
HgeneDENND1Achr9:126519981chr8:92231117ENST00000373624-52213_1451001010.0DomainuDENN
HgeneDENND1Achr9:126519981chr8:92231117ENST00000373624-522162_2981001010.0DomaincDENN
HgeneDENND1Achr9:126519981chr8:92231117ENST00000373624-522300_3781001010.0DomaindDENN
HgeneDENND1Achr9:126519981chr8:92231117ENST00000394215-42013_14570530.0DomainuDENN
HgeneDENND1Achr9:126519981chr8:92231117ENST00000394215-420162_29870530.0DomaincDENN
HgeneDENND1Achr9:126519981chr8:92231117ENST00000394215-420300_37870530.0DomaindDENN
HgeneDENND1Achr9:126519981chr8:92231117ENST00000394219-32113_145681021.0DomainuDENN
HgeneDENND1Achr9:126519981chr8:92231117ENST00000394219-321162_298681021.0DomaincDENN
HgeneDENND1Achr9:126519981chr8:92231117ENST00000394219-321300_378681021.0DomaindDENN
HgeneDENND1Achr9:126519981chr8:92231117ENST00000542603-11413_1450795.0DomainuDENN
HgeneDENND1Achr9:126519981chr8:92231117ENST00000542603-114162_2980795.0DomaincDENN
HgeneDENND1Achr9:126519981chr8:92231117ENST00000542603-114300_3780795.0DomaindDENN
HgeneDENND1Achr9:126519982chr8:92201750ENST00000373618-41913_14568467.0DomainuDENN
HgeneDENND1Achr9:126519982chr8:92201750ENST00000373618-419162_29868467.0DomaincDENN
HgeneDENND1Achr9:126519982chr8:92201750ENST00000373618-419300_37868467.0DomaindDENN
HgeneDENND1Achr9:126519982chr8:92201750ENST00000373620-52113_145100560.0DomainuDENN
HgeneDENND1Achr9:126519982chr8:92201750ENST00000373620-521162_298100560.0DomaincDENN
HgeneDENND1Achr9:126519982chr8:92201750ENST00000373620-521300_378100560.0DomaindDENN
HgeneDENND1Achr9:126519982chr8:92201750ENST00000373624-52213_1451001010.0DomainuDENN
HgeneDENND1Achr9:126519982chr8:92201750ENST00000373624-522162_2981001010.0DomaincDENN
HgeneDENND1Achr9:126519982chr8:92201750ENST00000373624-522300_3781001010.0DomaindDENN
HgeneDENND1Achr9:126519982chr8:92201750ENST00000394215-42013_14570530.0DomainuDENN
HgeneDENND1Achr9:126519982chr8:92201750ENST00000394215-420162_29870530.0DomaincDENN
HgeneDENND1Achr9:126519982chr8:92201750ENST00000394215-420300_37870530.0DomaindDENN
HgeneDENND1Achr9:126519982chr8:92201750ENST00000394219-32113_145681021.0DomainuDENN
HgeneDENND1Achr9:126519982chr8:92201750ENST00000394219-321162_298681021.0DomaincDENN
HgeneDENND1Achr9:126519982chr8:92201750ENST00000394219-321300_378681021.0DomaindDENN
HgeneDENND1Achr9:126519982chr8:92201750ENST00000542603-11413_1450795.0DomainuDENN
HgeneDENND1Achr9:126519982chr8:92201750ENST00000542603-114162_2980795.0DomaincDENN
HgeneDENND1Achr9:126519982chr8:92201750ENST00000542603-114300_3780795.0DomaindDENN
HgeneDENND1Achr9:126519982chr8:92231118ENST00000373618-41913_14568467.0DomainuDENN
HgeneDENND1Achr9:126519982chr8:92231118ENST00000373618-419162_29868467.0DomaincDENN
HgeneDENND1Achr9:126519982chr8:92231118ENST00000373618-419300_37868467.0DomaindDENN
HgeneDENND1Achr9:126519982chr8:92231118ENST00000373620-52113_145100560.0DomainuDENN
HgeneDENND1Achr9:126519982chr8:92231118ENST00000373620-521162_298100560.0DomaincDENN
HgeneDENND1Achr9:126519982chr8:92231118ENST00000373620-521300_378100560.0DomaindDENN
HgeneDENND1Achr9:126519982chr8:92231118ENST00000373624-52213_1451001010.0DomainuDENN
HgeneDENND1Achr9:126519982chr8:92231118ENST00000373624-522162_2981001010.0DomaincDENN
HgeneDENND1Achr9:126519982chr8:92231118ENST00000373624-522300_3781001010.0DomaindDENN
HgeneDENND1Achr9:126519982chr8:92231118ENST00000394215-42013_14570530.0DomainuDENN
HgeneDENND1Achr9:126519982chr8:92231118ENST00000394215-420162_29870530.0DomaincDENN
HgeneDENND1Achr9:126519982chr8:92231118ENST00000394215-420300_37870530.0DomaindDENN
HgeneDENND1Achr9:126519982chr8:92231118ENST00000394219-32113_145681021.0DomainuDENN
HgeneDENND1Achr9:126519982chr8:92231118ENST00000394219-321162_298681021.0DomaincDENN
HgeneDENND1Achr9:126519982chr8:92231118ENST00000394219-321300_378681021.0DomaindDENN
HgeneDENND1Achr9:126519982chr8:92231118ENST00000542603-11413_1450795.0DomainuDENN
HgeneDENND1Achr9:126519982chr8:92231118ENST00000542603-114162_2980795.0DomaincDENN
HgeneDENND1Achr9:126519982chr8:92231118ENST00000542603-114300_3780795.0DomaindDENN
HgeneDENND1Achr9:126519981chr8:92231117ENST00000373618-419381_38568467.0MotifFXDXF motif
HgeneDENND1Achr9:126519981chr8:92231117ENST00000373618-419569_57868467.0MotifClathrin box
HgeneDENND1Achr9:126519981chr8:92231117ENST00000373620-521381_385100560.0MotifFXDXF motif
HgeneDENND1Achr9:126519981chr8:92231117ENST00000373620-521569_578100560.0MotifClathrin box
HgeneDENND1Achr9:126519981chr8:92231117ENST00000373624-522381_3851001010.0MotifFXDXF motif
HgeneDENND1Achr9:126519981chr8:92231117ENST00000373624-522569_5781001010.0MotifClathrin box
HgeneDENND1Achr9:126519981chr8:92231117ENST00000394215-420381_38570530.0MotifFXDXF motif
HgeneDENND1Achr9:126519981chr8:92231117ENST00000394215-420569_57870530.0MotifClathrin box
HgeneDENND1Achr9:126519981chr8:92231117ENST00000394219-321381_385681021.0MotifFXDXF motif
HgeneDENND1Achr9:126519981chr8:92231117ENST00000394219-321569_578681021.0MotifClathrin box
HgeneDENND1Achr9:126519981chr8:92231117ENST00000542603-114381_3850795.0MotifFXDXF motif
HgeneDENND1Achr9:126519981chr8:92231117ENST00000542603-114569_5780795.0MotifClathrin box
HgeneDENND1Achr9:126519982chr8:92201750ENST00000373618-419381_38568467.0MotifFXDXF motif
HgeneDENND1Achr9:126519982chr8:92201750ENST00000373618-419569_57868467.0MotifClathrin box
HgeneDENND1Achr9:126519982chr8:92201750ENST00000373620-521381_385100560.0MotifFXDXF motif
HgeneDENND1Achr9:126519982chr8:92201750ENST00000373620-521569_578100560.0MotifClathrin box
HgeneDENND1Achr9:126519982chr8:92201750ENST00000373624-522381_3851001010.0MotifFXDXF motif
HgeneDENND1Achr9:126519982chr8:92201750ENST00000373624-522569_5781001010.0MotifClathrin box
HgeneDENND1Achr9:126519982chr8:92201750ENST00000394215-420381_38570530.0MotifFXDXF motif
HgeneDENND1Achr9:126519982chr8:92201750ENST00000394215-420569_57870530.0MotifClathrin box
HgeneDENND1Achr9:126519982chr8:92201750ENST00000394219-321381_385681021.0MotifFXDXF motif
HgeneDENND1Achr9:126519982chr8:92201750ENST00000394219-321569_578681021.0MotifClathrin box
HgeneDENND1Achr9:126519982chr8:92201750ENST00000542603-114381_3850795.0MotifFXDXF motif
HgeneDENND1Achr9:126519982chr8:92201750ENST00000542603-114569_5780795.0MotifClathrin box
HgeneDENND1Achr9:126519982chr8:92231118ENST00000373618-419381_38568467.0MotifFXDXF motif
HgeneDENND1Achr9:126519982chr8:92231118ENST00000373618-419569_57868467.0MotifClathrin box
HgeneDENND1Achr9:126519982chr8:92231118ENST00000373620-521381_385100560.0MotifFXDXF motif
HgeneDENND1Achr9:126519982chr8:92231118ENST00000373620-521569_578100560.0MotifClathrin box
HgeneDENND1Achr9:126519982chr8:92231118ENST00000373624-522381_3851001010.0MotifFXDXF motif
HgeneDENND1Achr9:126519982chr8:92231118ENST00000373624-522569_5781001010.0MotifClathrin box
HgeneDENND1Achr9:126519982chr8:92231118ENST00000394215-420381_38570530.0MotifFXDXF motif
HgeneDENND1Achr9:126519982chr8:92231118ENST00000394215-420569_57870530.0MotifClathrin box
HgeneDENND1Achr9:126519982chr8:92231118ENST00000394219-321381_385681021.0MotifFXDXF motif
HgeneDENND1Achr9:126519982chr8:92231118ENST00000394219-321569_578681021.0MotifClathrin box
HgeneDENND1Achr9:126519982chr8:92231118ENST00000542603-114381_3850795.0MotifFXDXF motif
HgeneDENND1Achr9:126519982chr8:92231118ENST00000542603-114569_5780795.0MotifClathrin box
TgeneLRRC69chr9:126519981chr8:92231117ENST0000034370924108_129155192.0RepeatNote=LRR 4
TgeneLRRC69chr9:126519981chr8:92231117ENST0000034370924131_153155192.0RepeatNote=LRR 5
TgeneLRRC69chr9:126519981chr8:92231117ENST000003437092438_60155192.0RepeatNote=LRR 1
TgeneLRRC69chr9:126519981chr8:92231117ENST000003437092461_82155192.0RepeatNote=LRR 2
TgeneLRRC69chr9:126519981chr8:92231117ENST000003437092484_105155192.0RepeatNote=LRR 3
TgeneLRRC69chr9:126519981chr8:92231117ENST0000044838468108_129311348.0RepeatNote=LRR 4
TgeneLRRC69chr9:126519981chr8:92231117ENST0000044838468131_153311348.0RepeatNote=LRR 5
TgeneLRRC69chr9:126519981chr8:92231117ENST0000044838468154_175311348.0RepeatNote=LRR 6
TgeneLRRC69chr9:126519981chr8:92231117ENST0000044838468177_199311348.0RepeatNote=LRR 7
TgeneLRRC69chr9:126519981chr8:92231117ENST0000044838468200_222311348.0RepeatNote=LRR 8
TgeneLRRC69chr9:126519981chr8:92231117ENST000004483846838_60311348.0RepeatNote=LRR 1
TgeneLRRC69chr9:126519981chr8:92231117ENST000004483846861_82311348.0RepeatNote=LRR 2
TgeneLRRC69chr9:126519981chr8:92231117ENST000004483846884_105311348.0RepeatNote=LRR 3
TgeneLRRC69chr9:126519982chr8:92201750ENST000003437090438_6061192.0RepeatNote=LRR 1
TgeneLRRC69chr9:126519982chr8:92201750ENST0000044838448108_129217348.0RepeatNote=LRR 4
TgeneLRRC69chr9:126519982chr8:92201750ENST0000044838448131_153217348.0RepeatNote=LRR 5
TgeneLRRC69chr9:126519982chr8:92201750ENST0000044838448154_175217348.0RepeatNote=LRR 6
TgeneLRRC69chr9:126519982chr8:92201750ENST0000044838448177_199217348.0RepeatNote=LRR 7
TgeneLRRC69chr9:126519982chr8:92201750ENST0000044838448200_222217348.0RepeatNote=LRR 8
TgeneLRRC69chr9:126519982chr8:92201750ENST000004483844838_60217348.0RepeatNote=LRR 1
TgeneLRRC69chr9:126519982chr8:92201750ENST000004483844861_82217348.0RepeatNote=LRR 2
TgeneLRRC69chr9:126519982chr8:92201750ENST000004483844884_105217348.0RepeatNote=LRR 3
TgeneLRRC69chr9:126519982chr8:92231118ENST0000034370924108_129155192.0RepeatNote=LRR 4
TgeneLRRC69chr9:126519982chr8:92231118ENST0000034370924131_153155192.0RepeatNote=LRR 5
TgeneLRRC69chr9:126519982chr8:92231118ENST000003437092438_60155192.0RepeatNote=LRR 1
TgeneLRRC69chr9:126519982chr8:92231118ENST000003437092461_82155192.0RepeatNote=LRR 2
TgeneLRRC69chr9:126519982chr8:92231118ENST000003437092484_105155192.0RepeatNote=LRR 3
TgeneLRRC69chr9:126519982chr8:92231118ENST0000044838468108_129311348.0RepeatNote=LRR 4
TgeneLRRC69chr9:126519982chr8:92231118ENST0000044838468131_153311348.0RepeatNote=LRR 5
TgeneLRRC69chr9:126519982chr8:92231118ENST0000044838468154_175311348.0RepeatNote=LRR 6
TgeneLRRC69chr9:126519982chr8:92231118ENST0000044838468177_199311348.0RepeatNote=LRR 7
TgeneLRRC69chr9:126519982chr8:92231118ENST0000044838468200_222311348.0RepeatNote=LRR 8
TgeneLRRC69chr9:126519982chr8:92231118ENST000004483846838_60311348.0RepeatNote=LRR 1
TgeneLRRC69chr9:126519982chr8:92231118ENST000004483846861_82311348.0RepeatNote=LRR 2
TgeneLRRC69chr9:126519982chr8:92231118ENST000004483846884_105311348.0RepeatNote=LRR 3


Top

Fusion Gene Sequence for DENND1A-LRRC69


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>22198_22198_1_DENND1A-LRRC69_DENND1A_chr9_126519981_ENST00000373618_LRRC69_chr8_92231117_ENST00000448384_length(transcript)=610nt_BP=499nt
GGCGGAGGGGGCGGCGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCG
GCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTC
GGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAA
TCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCC
GGAGGACTACAGTGACCAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCG
GGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGGACTGGAAGATAAGCAAGAATCTGAAGCTGGTGCCTCTCCA

>22198_22198_1_DENND1A-LRRC69_DENND1A_chr9_126519981_ENST00000373618_LRRC69_chr8_92231117_ENST00000448384_length(amino acids)=126AA_BP=
MREGRKGRGERQREAGRPRAGGQRSAERGPRAHEEAWGPWAPGSSRIQRPHLKYMLKWPIPGQVALFQILRCRGNSRRTTVTSLTVSQVG

--------------------------------------------------------------
>22198_22198_2_DENND1A-LRRC69_DENND1A_chr9_126519981_ENST00000373620_LRRC69_chr8_92231117_ENST00000343709_length(transcript)=761nt_BP=523nt
ACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAG
CGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGCGGGCAGCGCAGC
GCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATG
TTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCCGGAGGACTACAGTGACCAGGAAGTTC
TACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTG
ACATTGACAGCAAACAGAGATTCGGGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGGACTGGAAGATAAGCAA
GAATCTGAAGCTGGTGCCTCTCCAAGTATTAATTTGTTCTTACAAATGTTTTACTCAACGTGACCCTAACCTCTTTGGAATTGCTCAGGT
GTAGAACAGGTGAGGTGCTCATTCATAGCCTCACTCCACTTGCCCTGTCAGCTCTGCATACACAGATTATGCCCTACTTAAGATACCATG

>22198_22198_2_DENND1A-LRRC69_DENND1A_chr9_126519981_ENST00000373620_LRRC69_chr8_92231117_ENST00000343709_length(amino acids)=107AA_BP=
MGTMGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVDSLTVSQVGQNFTFVLTDIDSKQRFGFC

--------------------------------------------------------------
>22198_22198_3_DENND1A-LRRC69_DENND1A_chr9_126519981_ENST00000373624_LRRC69_chr8_92231117_ENST00000343709_length(transcript)=742nt_BP=504nt
GCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGA
GGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGG
CCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAG
GACAGGTGGCACTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCCGGAGGACTACAGTGACCAGGAAGTTCTACAGACTTTGACCAAGTT
TTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAG
ATTCGGGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGGACTGGAAGATAAGCAAGAATCTGAAGCTGGTGCCT
CTCCAAGTATTAATTTGTTCTTACAAATGTTTTACTCAACGTGACCCTAACCTCTTTGGAATTGCTCAGGTGTAGAACAGGTGAGGTGCT
CATTCATAGCCTCACTCCACTTGCCCTGTCAGCTCTGCATACACAGATTATGCCCTACTTAAGATACCATGCCTGTTCTCTTTGTCAACA

>22198_22198_3_DENND1A-LRRC69_DENND1A_chr9_126519981_ENST00000373624_LRRC69_chr8_92231117_ENST00000343709_length(amino acids)=107AA_BP=
MGTMGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVDSLTVSQVGQNFTFVLTDIDSKQRFGFC

--------------------------------------------------------------
>22198_22198_4_DENND1A-LRRC69_DENND1A_chr9_126519981_ENST00000394215_LRRC69_chr8_92231117_ENST00000448384_length(transcript)=602nt_BP=491nt
CGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGA
GCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGC
GGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACAT
TTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTC
TATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGC
CGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGGACTGGAAGATAAGCAAGAATCTGAAGCTGGTGCCTCTCCAAGTATTAA

>22198_22198_4_DENND1A-LRRC69_DENND1A_chr9_126519981_ENST00000394215_LRRC69_chr8_92231117_ENST00000448384_length(amino acids)=128AA_BP=
MREGRKGRGERQREAGRPRAGGQRSAERGPRAHEEAWGPWAPGSSRIQRPHLKYMLKWPIPGQVALFQEVLQTLTKFCFPFYVDSLTVSQ

--------------------------------------------------------------
>22198_22198_5_DENND1A-LRRC69_DENND1A_chr9_126519981_ENST00000394219_LRRC69_chr8_92231117_ENST00000343709_length(transcript)=634nt_BP=396nt
GACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCC
AGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGC
CCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGT
GGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGCCGCTT
ATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGGACTGGAAGATAAGCAAGAATCTGAAGCTGGTGCCTCTCCAAGTATTAATTTGT
TCTTACAAATGTTTTACTCAACGTGACCCTAACCTCTTTGGAATTGCTCAGGTGTAGAACAGGTGAGGTGCTCATTCATAGCCTCACTCC
ACTTGCCCTGTCAGCTCTGCATACACAGATTATGCCCTACTTAAGATACCATGCCTGTTCTCTTTGTCAACACATTAAATAAAGGAAGAA

>22198_22198_5_DENND1A-LRRC69_DENND1A_chr9_126519981_ENST00000394219_LRRC69_chr8_92231117_ENST00000343709_length(amino acids)=75AA_BP=

--------------------------------------------------------------
>22198_22198_6_DENND1A-LRRC69_DENND1A_chr9_126519982_ENST00000373618_LRRC69_chr8_92201750_ENST00000343709_length(transcript)=1019nt_BP=499nt
GGCGGAGGGGGCGGCGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCG
GCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTC
GGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAA
TCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCC
GGAGGACTACAGTGACCAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCG
GGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGTTTCAGGATCTGAAGCTGAGGGAATTCTACTGTGAGGGAAA
CCCACTGTTCCTGCAGCAGCCAGTGATTTCTACACAGCAGGAGAACGTCTGGAGTCTACAGGAAATAACATCAAGATTTGTAATGAATCA
GCTAGCAGAAAATAACCCTTTCCTAATGGATGACATAGAACGGTACCCACAAGTCAGGAGCATGATCTCTCAGGGAAAAACATGTGCAAT
ATGTGGACAGTACTTTATAACCGTATGGCTGGAATGTGTTCGATTTGTTCCTCCACCAAAGGACTGGAAGATAAGCAAGAATCTGAAGCT
GGTGCCTCTCCAAGTATTAATTTGTTCTTACAAATGTTTTACTCAACGTGACCCTAACCTCTTTGGAATTGCTCAGGTGTAGAACAGGTG
AGGTGCTCATTCATAGCCTCACTCCACTTGCCCTGTCAGCTCTGCATACACAGATTATGCCCTACTTAAGATACCATGCCTGTTCTCTTT

>22198_22198_6_DENND1A-LRRC69_DENND1A_chr9_126519982_ENST00000373618_LRRC69_chr8_92201750_ENST00000343709_length(amino acids)=145AA_BP=9
MPLIFRSEELLLYLKFQDLKLREFYCEGNPLFLQQPVISTQQENVWSLQEITSRFVMNQLAENNPFLMDDIERYPQVRSMISQGKTCAIC

--------------------------------------------------------------
>22198_22198_7_DENND1A-LRRC69_DENND1A_chr9_126519982_ENST00000373618_LRRC69_chr8_92201750_ENST00000448384_length(transcript)=892nt_BP=499nt
GGCGGAGGGGGCGGCGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCG
GCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTC
GGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAA
TCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCC
GGAGGACTACAGTGACCAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCG
GGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGTTTCAGGATCTGAAGCTGAGGGAATTCTACTGTGAGGGAAA
CCCACTGTTCCTGCAGCAGCCAGTGATTTCTACACAGCAGGAGAACGTCTGGAGTCTACAGGAAATAACATCAAGATTTGTAATGAATCA
GCTAGCAGAAAATAACCCTTTCCTAATGGATGACATAGAACGGTACCCACAAGTCAGGAGCATGATCTCTCAGGGAAAAACATGTGCAAT
ATGTGGACAGTACTTTATAACCGTATGGCTGGAATGTGTTCGATTTGTTCCTCCACCAAAGGACTGGAAGATAAGCAAGAATCTGAAGCT

>22198_22198_7_DENND1A-LRRC69_DENND1A_chr9_126519982_ENST00000373618_LRRC69_chr8_92201750_ENST00000448384_length(amino acids)=146AA_BP=9
MPLIFRSEELLLYLKFQDLKLREFYCEGNPLFLQQPVISTQQENVWSLQEITSRFVMNQLAENNPFLMDDIERYPQVRSMISQGKTCAIC

--------------------------------------------------------------
>22198_22198_8_DENND1A-LRRC69_DENND1A_chr9_126519982_ENST00000373618_LRRC69_chr8_92231118_ENST00000448384_length(transcript)=610nt_BP=499nt
GGCGGAGGGGGCGGCGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCG
GCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTC
GGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAA
TCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCC
GGAGGACTACAGTGACCAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCG
GGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGGACTGGAAGATAAGCAAGAATCTGAAGCTGGTGCCTCTCCA

>22198_22198_8_DENND1A-LRRC69_DENND1A_chr9_126519982_ENST00000373618_LRRC69_chr8_92231118_ENST00000448384_length(amino acids)=126AA_BP=
MREGRKGRGERQREAGRPRAGGQRSAERGPRAHEEAWGPWAPGSSRIQRPHLKYMLKWPIPGQVALFQILRCRGNSRRTTVTSLTVSQVG

--------------------------------------------------------------
>22198_22198_9_DENND1A-LRRC69_DENND1A_chr9_126519982_ENST00000373620_LRRC69_chr8_92231118_ENST00000343709_length(transcript)=761nt_BP=523nt
ACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAG
CGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGCGGGCAGCGCAGC
GCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATG
TTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCCGGAGGACTACAGTGACCAGGAAGTTC
TACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTG
ACATTGACAGCAAACAGAGATTCGGGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGGACTGGAAGATAAGCAA
GAATCTGAAGCTGGTGCCTCTCCAAGTATTAATTTGTTCTTACAAATGTTTTACTCAACGTGACCCTAACCTCTTTGGAATTGCTCAGGT
GTAGAACAGGTGAGGTGCTCATTCATAGCCTCACTCCACTTGCCCTGTCAGCTCTGCATACACAGATTATGCCCTACTTAAGATACCATG

>22198_22198_9_DENND1A-LRRC69_DENND1A_chr9_126519982_ENST00000373620_LRRC69_chr8_92231118_ENST00000343709_length(amino acids)=107AA_BP=
MGTMGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVDSLTVSQVGQNFTFVLTDIDSKQRFGFC

--------------------------------------------------------------
>22198_22198_10_DENND1A-LRRC69_DENND1A_chr9_126519982_ENST00000373624_LRRC69_chr8_92231118_ENST00000343709_length(transcript)=742nt_BP=504nt
GCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCCAGCCTGA
GGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGCCCGCGGG
CCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACATTTGAAGTATATGTTGAAGTGGCCTATCCCAG
GACAGGTGGCACTCTTTCAGATCCTGAGGTGCAGAGGCAATTCCCGGAGGACTACAGTGACCAGGAAGTTCTACAGACTTTGACCAAGTT
TTGTTTCCCCTTCTATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAG
ATTCGGGTTCTGCCGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGGACTGGAAGATAAGCAAGAATCTGAAGCTGGTGCCT
CTCCAAGTATTAATTTGTTCTTACAAATGTTTTACTCAACGTGACCCTAACCTCTTTGGAATTGCTCAGGTGTAGAACAGGTGAGGTGCT
CATTCATAGCCTCACTCCACTTGCCCTGTCAGCTCTGCATACACAGATTATGCCCTACTTAAGATACCATGCCTGTTCTCTTTGTCAACA

>22198_22198_10_DENND1A-LRRC69_DENND1A_chr9_126519982_ENST00000373624_LRRC69_chr8_92231118_ENST00000343709_length(amino acids)=107AA_BP=
MGTMGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVDSLTVSQVGQNFTFVLTDIDSKQRFGFC

--------------------------------------------------------------
>22198_22198_11_DENND1A-LRRC69_DENND1A_chr9_126519982_ENST00000394215_LRRC69_chr8_92201750_ENST00000343709_length(transcript)=1011nt_BP=491nt
CGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGA
GCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGC
GGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACAT
TTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTC
TATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGC
CGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGTTTCAGGATCTGAAGCTGAGGGAATTCTACTGTGAGGGAAACCCACTGT
TCCTGCAGCAGCCAGTGATTTCTACACAGCAGGAGAACGTCTGGAGTCTACAGGAAATAACATCAAGATTTGTAATGAATCAGCTAGCAG
AAAATAACCCTTTCCTAATGGATGACATAGAACGGTACCCACAAGTCAGGAGCATGATCTCTCAGGGAAAAACATGTGCAATATGTGGAC
AGTACTTTATAACCGTATGGCTGGAATGTGTTCGATTTGTTCCTCCACCAAAGGACTGGAAGATAAGCAAGAATCTGAAGCTGGTGCCTC
TCCAAGTATTAATTTGTTCTTACAAATGTTTTACTCAACGTGACCCTAACCTCTTTGGAATTGCTCAGGTGTAGAACAGGTGAGGTGCTC
ATTCATAGCCTCACTCCACTTGCCCTGTCAGCTCTGCATACACAGATTATGCCCTACTTAAGATACCATGCCTGTTCTCTTTGTCAACAC

>22198_22198_11_DENND1A-LRRC69_DENND1A_chr9_126519982_ENST00000394215_LRRC69_chr8_92201750_ENST00000343709_length(amino acids)=145AA_BP=9
MPLIFRSEELLLYLKFQDLKLREFYCEGNPLFLQQPVISTQQENVWSLQEITSRFVMNQLAENNPFLMDDIERYPQVRSMISQGKTCAIC

--------------------------------------------------------------
>22198_22198_12_DENND1A-LRRC69_DENND1A_chr9_126519982_ENST00000394215_LRRC69_chr8_92201750_ENST00000448384_length(transcript)=884nt_BP=491nt
CGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGA
GCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGC
GGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACAT
TTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTC
TATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGC
CGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGTTTCAGGATCTGAAGCTGAGGGAATTCTACTGTGAGGGAAACCCACTGT
TCCTGCAGCAGCCAGTGATTTCTACACAGCAGGAGAACGTCTGGAGTCTACAGGAAATAACATCAAGATTTGTAATGAATCAGCTAGCAG
AAAATAACCCTTTCCTAATGGATGACATAGAACGGTACCCACAAGTCAGGAGCATGATCTCTCAGGGAAAAACATGTGCAATATGTGGAC
AGTACTTTATAACCGTATGGCTGGAATGTGTTCGATTTGTTCCTCCACCAAAGGACTGGAAGATAAGCAAGAATCTGAAGCTGGTGCCTC

>22198_22198_12_DENND1A-LRRC69_DENND1A_chr9_126519982_ENST00000394215_LRRC69_chr8_92201750_ENST00000448384_length(amino acids)=146AA_BP=9
MPLIFRSEELLLYLKFQDLKLREFYCEGNPLFLQQPVISTQQENVWSLQEITSRFVMNQLAENNPFLMDDIERYPQVRSMISQGKTCAIC

--------------------------------------------------------------
>22198_22198_13_DENND1A-LRRC69_DENND1A_chr9_126519982_ENST00000394215_LRRC69_chr8_92231118_ENST00000448384_length(transcript)=602nt_BP=491nt
CGCGCGCCGGGCACGCGCGCCGGCGACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGA
GCGAGCCTCGAGCGGGCGGGCCCCAGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGC
GGGCAGCGCAGCGCCGAGCGGGGCCCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGCAGAATCCAGAGACCACAT
TTGAAGTATATGTTGAAGTGGCCTATCCCAGGACAGGTGGCACTCTTTCAGGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTC
TATGTGGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGC
CGCTTATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGGACTGGAAGATAAGCAAGAATCTGAAGCTGGTGCCTCTCCAAGTATTAA

>22198_22198_13_DENND1A-LRRC69_DENND1A_chr9_126519982_ENST00000394215_LRRC69_chr8_92231118_ENST00000448384_length(amino acids)=128AA_BP=
MREGRKGRGERQREAGRPRAGGQRSAERGPRAHEEAWGPWAPGSSRIQRPHLKYMLKWPIPGQVALFQEVLQTLTKFCFPFYVDSLTVSQ

--------------------------------------------------------------
>22198_22198_14_DENND1A-LRRC69_DENND1A_chr9_126519982_ENST00000394219_LRRC69_chr8_92231118_ENST00000343709_length(transcript)=634nt_BP=396nt
GACCATGGCGTTCGCCGGGCTGGAGCGAGTACATTAACCCCTGGAGGCGGCGGCGGCGGCGAGGGAGCGAGCCTCGAGCGGGCGGGCCCC
AGCCTGAGGGAAGGGAGGAAGGGGCGGGGAGAGCGCCAGAGGGAGGCCGGTCGGCCGCGGGCGGGCGGGCAGCGCAGCGCCGAGCGGGGC
CCGCGGGCCCATGAGGAGGCCTGGGGACCATGGGCTCCAGGATCAAGAAGTTCTACAGACTTTGACCAAGTTTTGTTTCCCCTTCTATGT
GGACAGCCTCACAGTTAGCCAAGTTGGCCAGAACTTCACATTCGTGCTCACTGACATTGACAGCAAACAGAGATTCGGGTTCTGCCGCTT
ATCTTCAGGAGCGAAGAGCTGCTTCTGTATCTTAAGGACTGGAAGATAAGCAAGAATCTGAAGCTGGTGCCTCTCCAAGTATTAATTTGT
TCTTACAAATGTTTTACTCAACGTGACCCTAACCTCTTTGGAATTGCTCAGGTGTAGAACAGGTGAGGTGCTCATTCATAGCCTCACTCC
ACTTGCCCTGTCAGCTCTGCATACACAGATTATGCCCTACTTAAGATACCATGCCTGTTCTCTTTGTCAACACATTAAATAAAGGAAGAA

>22198_22198_14_DENND1A-LRRC69_DENND1A_chr9_126519982_ENST00000394219_LRRC69_chr8_92231118_ENST00000343709_length(amino acids)=75AA_BP=

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for DENND1A-LRRC69


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for DENND1A-LRRC69


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for DENND1A-LRRC69


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource