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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DEPDC5-CELSR1 (FusionGDB2 ID:22311)

Fusion Gene Summary for DEPDC5-CELSR1

check button Fusion gene summary
Fusion gene informationFusion gene name: DEPDC5-CELSR1
Fusion gene ID: 22311
HgeneTgene
Gene symbol

DEPDC5

CELSR1

Gene ID

9681

9620

Gene nameDEP domain containing 5, GATOR1 subcomplex subunitcadherin EGF LAG seven-pass G-type receptor 1
SynonymsDEP.5|FFEVF|FFEVF1ADGRC1|CDHF9|FMI2|HFMI2|ME2
Cytomap

22q12.2-q12.3

22q13.31

Type of geneprotein-codingprotein-coding
DescriptionGATOR complex protein DEPDC5DEP domain containing 5DEP domain-containing protein 5cadherin EGF LAG seven-pass G-type receptor 1adhesion G protein-coupled receptor C1cadherin family member 9cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)flamingo homolog 2protocadherin flamingo 2
Modification date2020031520200322
UniProtAcc

O75140

Q9NYQ6

Ensembl transtripts involved in fusion geneENST00000266091, ENST00000382105, 
ENST00000382111, ENST00000382112, 
ENST00000400246, ENST00000400248, 
ENST00000400249, ENST00000535622, 
ENST00000539165, ENST00000400242, 
ENST00000494060, ENST00000536766, 
ENST00000395964, ENST00000497509, 
ENST00000262738, 
Fusion gene scores* DoF score15 X 15 X 5=11257 X 7 X 4=196
# samples 147
** MAII scorelog2(14/1125*10)=-3.00642626915943
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/196*10)=-1.48542682717024
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DEPDC5 [Title/Abstract] AND CELSR1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDEPDC5(32275603)-CELSR1(46792627), # samples:1
Anticipated loss of major functional domain due to fusion event.DEPDC5-CELSR1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
DEPDC5-CELSR1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
DEPDC5-CELSR1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across DEPDC5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CELSR1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ABF845393DEPDC5chr22

32275603

+CELSR1chr22

46792627

-


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Fusion Gene ORF analysis for DEPDC5-CELSR1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000266091ENST00000395964DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
5CDS-intronENST00000266091ENST00000497509DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
5CDS-intronENST00000382105ENST00000395964DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
5CDS-intronENST00000382105ENST00000497509DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
5CDS-intronENST00000382111ENST00000395964DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
5CDS-intronENST00000382111ENST00000497509DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
5CDS-intronENST00000382112ENST00000395964DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
5CDS-intronENST00000382112ENST00000497509DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
5CDS-intronENST00000400246ENST00000395964DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
5CDS-intronENST00000400246ENST00000497509DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
5CDS-intronENST00000400248ENST00000395964DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
5CDS-intronENST00000400248ENST00000497509DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
5CDS-intronENST00000400249ENST00000395964DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
5CDS-intronENST00000400249ENST00000497509DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
5CDS-intronENST00000535622ENST00000395964DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
5CDS-intronENST00000535622ENST00000497509DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
5CDS-intronENST00000539165ENST00000395964DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
5CDS-intronENST00000539165ENST00000497509DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
Frame-shiftENST00000382105ENST00000262738DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
In-frameENST00000266091ENST00000262738DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
In-frameENST00000382111ENST00000262738DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
In-frameENST00000382112ENST00000262738DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
In-frameENST00000400246ENST00000262738DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
In-frameENST00000400248ENST00000262738DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
In-frameENST00000400249ENST00000262738DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
In-frameENST00000535622ENST00000262738DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
In-frameENST00000539165ENST00000262738DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
intron-3CDSENST00000400242ENST00000262738DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
intron-3CDSENST00000494060ENST00000262738DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
intron-3CDSENST00000536766ENST00000262738DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
intron-intronENST00000400242ENST00000395964DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
intron-intronENST00000400242ENST00000497509DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
intron-intronENST00000494060ENST00000395964DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
intron-intronENST00000494060ENST00000497509DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
intron-intronENST00000536766ENST00000395964DEPDC5chr22

32275603

+CELSR1chr22

46792627

-
intron-intronENST00000536766ENST00000497509DEPDC5chr22

32275603

+CELSR1chr22

46792627

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000535622DEPDC5chr2232275603+ENST00000262738CELSR1chr2246792627-939037187838001240
ENST00000400246DEPDC5chr2232275603+ENST00000262738CELSR1chr2246792627-9754408214241641340
ENST00000266091DEPDC5chr2232275603+ENST00000262738CELSR1chr2246792627-9688401614240981318
ENST00000400249DEPDC5chr2232275603+ENST00000262738CELSR1chr2246792627-9661398914240711309
ENST00000382112DEPDC5chr2232275603+ENST00000262738CELSR1chr2246792627-965539837040651331
ENST00000382111DEPDC5chr2232275603+ENST00000262738CELSR1chr2246792627-967240006040821340
ENST00000400248DEPDC5chr2232275603+ENST00000262738CELSR1chr2246792627-957839065939881309
ENST00000539165DEPDC5chr2232275603+ENST00000262738CELSR1chr2246792627-655187943985288296

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000535622ENST00000262738DEPDC5chr2232275603+CELSR1chr2246792627-0.0004327270.9995672
ENST00000400246ENST00000262738DEPDC5chr2232275603+CELSR1chr2246792627-0.0012521630.9987478
ENST00000266091ENST00000262738DEPDC5chr2232275603+CELSR1chr2246792627-0.0011601790.9988398
ENST00000400249ENST00000262738DEPDC5chr2232275603+CELSR1chr2246792627-0.0007969840.999203
ENST00000382112ENST00000262738DEPDC5chr2232275603+CELSR1chr2246792627-0.0008854870.99911445
ENST00000382111ENST00000262738DEPDC5chr2232275603+CELSR1chr2246792627-0.0011439060.99885607
ENST00000400248ENST00000262738DEPDC5chr2232275603+CELSR1chr2246792627-0.0007221430.9992779
ENST00000539165ENST00000262738DEPDC5chr2232275603+CELSR1chr2246792627-0.45418220.5458178

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Fusion Genomic Features for DEPDC5-CELSR1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for DEPDC5-CELSR1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:32275603/chr22:46792627)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DEPDC5

O75140

CELSR1

Q9NYQ6

FUNCTION: As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. The GATOR1 complex strongly increases GTP hydrolysis by RRAGA and RRAGB within RRAGC-containing heterodimers, thereby deactivating RRAGs, releasing mTORC1 from lysosomal surface and inhibiting mTORC1 signaling. The GATOR1 complex is negatively regulated by GATOR2 the other GATOR subcomplex in this amino acid-sensing branch of the TORC1 pathway. {ECO:0000269|PubMed:23723238, ECO:0000269|PubMed:25457612, ECO:0000269|PubMed:29769719}.FUNCTION: Receptor that may have an important role in cell/cell signaling during nervous system formation.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380352659_266303015.0Compositional biasNote=Poly-Leu
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380351000_110103015.0DomainCadherin 8
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380351106_122403015.0DomainCadherin 9
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380351303_136103015.0DomainEGF-like 1%3B calcium-binding
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380351363_139903015.0DomainEGF-like 2%3B calcium-binding
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380351403_144103015.0DomainEGF-like 3%3B calcium-binding
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380351442_164603015.0DomainLaminin G-like 1
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380351649_168503015.0DomainEGF-like 4%3B calcium-binding
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380351689_187003015.0DomainLaminin G-like 2
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380351872_190703015.0DomainEGF-like 5%3B calcium-binding
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380351908_194603015.0DomainEGF-like 6%3B calcium-binding
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380351947_197903015.0DomainEGF-like 7%3B calcium-binding
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380351981_201603015.0DomainEGF-like 8%3B calcium-binding
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380352003_205003015.0DomainLaminin EGF-like
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380352408_246003015.0DomainGPS
TgeneCELSR1chr22:32275603chr22:46792627ENST00000262738035246_35303015.0DomainCadherin 1
TgeneCELSR1chr22:32275603chr22:46792627ENST00000262738035354_45903015.0DomainCadherin 2
TgeneCELSR1chr22:32275603chr22:46792627ENST00000262738035460_56503015.0DomainCadherin 3
TgeneCELSR1chr22:32275603chr22:46792627ENST00000262738035566_68703015.0DomainCadherin 4
TgeneCELSR1chr22:32275603chr22:46792627ENST00000262738035688_78903015.0DomainCadherin 5
TgeneCELSR1chr22:32275603chr22:46792627ENST00000262738035790_89203015.0DomainCadherin 6
TgeneCELSR1chr22:32275603chr22:46792627ENST00000262738035893_99903015.0DomainCadherin 7
TgeneCELSR1chr22:32275603chr22:46792627ENST0000026273803522_246903015.0Topological domainExtracellular
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380352491_250103015.0Topological domainCytoplasmic
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380352523_252703015.0Topological domainExtracellular
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380352549_257203015.0Topological domainCytoplasmic
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380352594_261103015.0Topological domainExtracellular
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380352633_265503015.0Topological domainCytoplasmic
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380352677_268303015.0Topological domainExtracellular
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380352705_301403015.0Topological domainCytoplasmic
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380352470_249003015.0TransmembraneHelical%3B Name%3D1
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380352502_252203015.0TransmembraneHelical%3B Name%3D2
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380352528_254803015.0TransmembraneHelical%3B Name%3D3
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380352573_259303015.0TransmembraneHelical%3B Name%3D4
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380352612_263203015.0TransmembraneHelical%3B Name%3D5
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380352656_267603015.0TransmembraneHelical%3B Name%3D6
TgeneCELSR1chr22:32275603chr22:46792627ENST000002627380352684_270403015.0TransmembraneHelical%3B Name%3D7

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDEPDC5chr22:32275603chr22:46792627ENST00000266091+1421187_126201582.0DomainDEP
HgeneDEPDC5chr22:32275603chr22:46792627ENST00000382111+1411187_126201553.0DomainDEP
HgeneDEPDC5chr22:32275603chr22:46792627ENST00000382112+1421187_126201595.0DomainDEP
HgeneDEPDC5chr22:32275603chr22:46792627ENST00000400242+1221187_12620560.0DomainDEP
HgeneDEPDC5chr22:32275603chr22:46792627ENST00000400246+1421187_126201553.0DomainDEP
HgeneDEPDC5chr22:32275603chr22:46792627ENST00000400248+1411187_126201573.0DomainDEP
HgeneDEPDC5chr22:32275603chr22:46792627ENST00000400249+1421187_126201573.0DomainDEP
HgeneDEPDC5chr22:32275603chr22:46792627ENST00000535622+1401187_126201504.0DomainDEP


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Fusion Gene Sequence for DEPDC5-CELSR1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>22311_22311_1_DEPDC5-CELSR1_DEPDC5_chr22_32275603_ENST00000266091_CELSR1_chr22_46792627_ENST00000262738_length(transcript)=9688nt_BP=4016nt
ATCTGGAGGAGGCGCAGGGAACCTGGAGAGGGTCCAGCCCTCAGTGCCCCGGCCAGAGGCGGGAAGGGGCTCTAGAGCTTCGGGAGGCAA
GATGACTTCTCTGCCCCAAGCTTGGAACAGCTAAAGGGAAAAACAGTGCAAGATGAGAACAACAAAGGTCTACAAACTCGTCATCCACAA
GAAGGGCTTTGGGGGCAGTGATGATGAGCTAGTTGTGAACCCCAAAGTGTTCCCTCACATCAAGCTTGGAGACATTGTAGAGATTGCACA
CCCCAACGATGAATACAGCCCTCTGCTTTTGCAGGTCAAGTCTCTTAAGGAAGATTTACAGAAGGAAACTATCAGTGTGGACCAGACTGT
GACTCAAGTGTTCCGGCTGAGACCTTATCAGGATGTCTATGTTAATGTCGTAGACCCTAAGGATGTGACCCTTGACCTAGTGGAATTAAC
TTTTAAGGATCAGTATATTGGCCGTGGGGATATGTGGCGACTAAAGAAAAGTTTGGTCAGCACATGTGCCTATATCACCCAGAAGGTGGA
GTTTGCTGGCATCAGAGCACAGGCTGGTGAACTGTGGGTTAAGAATGAGAAGGTCATGTGTGGCTACATCAGTGAAGATACCAGGGTGGT
GTTTCGTTCTACGTCGGCTATGGTTTACATATTTATTCAGATGAGCTGTGAAATGTGGGATTTTGATATTTATGGGGATTTGTATTTTGA
GAAAGCTGTGAATGGTTTCCTTGCTGATCTATTTACCAAGTGGAAGGAGAAGAACTGTAGTCATGAAGTGACAGTGGTCCTGTTTTCTAG
AACTTTCTATGATGCAAAATCTGTTGATGAATTTCCTGAAATAAACCGAGCCTCAATTCGACAGGATCACAAGGGGAGATTCTATGAAGA
CTTTTACAAAGTGGTGGTGCAGAATGAGAGAAGAGAAGAATGGACTTCACTTCTCGTAACCATTAAAAAACTCTTCATCCAGTATCCAGT
GTTGGTGCGACTGGAACAGGCAGAGGGCTTTCCTCAAGGAGATAATTCTACCTCAGCACAAGGAAACTACCTGGAGGCCATCAATCTGTC
ATTCAATGTGTTTGATAAGCACTACATCAACCGCAACTTTGACCGAACTGGGCAGATGTCAGTGGTGATCACGCCCGGGGTGGGTGTCTT
TGAAGTGGACCGCCTACTCATGATCCTGACCAAGCAGCGGATGATAGATAATGGAATTGGTGTGGATTTGGTGTGCATGGGAGAGCAACC
GTTACATGCTGTCCCATTGTTCAAGCTCCATAATCGGAGTGCTCCCCGTGATTCTCGTCTGGGCGATGACTATAATATCCCTCACTGGAT
AAACCACAGTTTCTACACATCCAAAAGCCAGCTCTTTTGTAATAGTTTCACCCCACGAATAAAACTGGCAGGAAAGAAGCCCGCCTCTGA
GAAAGCAAAAAATGGCCGTGATACATCTCTCGGGAGTCCAAAAGAATCTGAGAACGCCCTTCCCATCCAAGTAGATTATGACGCCTATGA
CGCTCAAGTGTTCAGGCTGCCCGGCCCATCCCGGGCCCAGTGCCTCACCACCTGCAGATCTGTGCGAGAGCGAGAGAGTCACAGTCGAAA
GAGTGCCAGCTCCTGTGATGTTTCATCCAGCCCTTCCCTACCAAGCCGCACACTGCCCACTGAGGAAGTGAGGAGCCAGGCTTCTGACGA
CAGCTCCCTAGGCAAGAGTGCCAACATCCTGATGATCCCACACCCCCACCTGCACCAGTATGAAGTCAGCAGCTCCTTGGGATACACCAG
CACTCGAGATGTCCTGGAGAACATGATGGAGCCACCACAGCGAGACTCCAGTGCACCAGGGAGGTTTCACGTTGGCAGTGCAGAATCCAT
GCTGCATGTTCGACCTGGTGGATACACGCCCCAGAGAGCACTGATTAACCCCTTCGCTCCCTCTCGGATGCCCATGAAGCTTACGTCCAA
CAGAAGGCGCTGGATGCACACTTTTCCTGTGGGGCCATCCGGAGAAGCCATCCAGATCCACCACCAGACCCGACAGAATATGGCGGAGCT
ACAAGGCAGCGGGCAGAGGGATCCAACTCACTCCTCTGCAGAGCTGCTGGAGTTAGCATATCATGAAGCTGCTGGAAGGCACAGCAATTC
CCGCCAGCCTGGTGACGGCATGTCCTTCTTGAACTTCAGTGGAACAGAGGAGCTTTCTGTCGGCCTGCTTAGCAACAGTGGTGCAGGTAT
GAATCCTAGGACCCAGAATAAGGATTCTCTAGAGGACAGTGTTTCTACCTCTCCAGACCCAATTCTGACACTGTCTGCTCCCCCTGTAGT
GCCAGGCTTCTGTTGCACAGTTGGAGTGGACTGGAAGTCTCTCACTACTCCGGCGTGCCTCCCCCTTACCACCGACTACTTCCCTGACCG
CCAGGGCCTGCAGAATGACTACACAGAGGGCTGTTATGATCTCCTTCCAGAAGCAGACATCGACAGGAGGGACGAAGATGGTGTGCAGAT
GACAGCCCAGCAGGTATTTGAAGAGTTTATTTGCCAACGTCTCATGCAGGGCTACCAAATCATAGTGCAGCCCAAGACACAGAAACCCAA
TCCTGCTGTCCCGCCCCCGCTGAGCAGTAGCCCACTCTATAGCCGAGGCCTTGTGTCCCGAAACCGCCCTGAGGAGGAGGACCAGTATTG
GCTGAGTATGGGCAGAACGTTCCACAAAGTGACGCTGAAGGATAAGATGATCACAGTGACGCGATACCTTCCCAAGTATCCTTATGAATC
TGCCCAGATCCACTACACCTACAGCCTCTGTCCTTCCCACTCAGACTCAGAGTTCGTCTCCTGCTGGGTGGAATTCTCCCACGAACGGCT
GGAGGAGTACAAGTGGAATTACTTAGATCAGTATATCTGTTCTGCCGGCTCTGAAGACTTCAGCTTAATTGAGTCCCTGAAGTTCTGGAG
GACCCGCTTCCTGCTGCTGCCAGCCTGTGTCACCGCCACCAAGCGCATCACGGAGGGGGAGGCCCACTGCGACATCTATGGGGACAGGCC
CCGTGCAGACGAGGACGAGTGGCAACTCCTGGATGGTTTTGTCCGCTTTGTGGAGGGCTTGAATCGCATTCGCAGGCGGCATCGCTCGGA
TCGCATGATGCGGAAAGGGACCGCCATGAAAGGCTTGCAGATGACTGGGCCCATTTCCACGCATTCTCTGGAGTCAACTGCACCCCCAGT
GGGGAAGAAGGGAACCTCAGCTCTCTCTGCCCTGTTGGAGATGGAGGCCAGTCAGAAGTGCCTGGGAGAACAGCAGGCAGCTGTGCATGG
TGGGAAGAGCTCCGCCCAGTCAGCCGAGAGCAGCAGCGTTGCCATGACTCCCACCTACATGGACAGCCCACGAAAGGTATCTGTGGACCA
AACAGCCACTCCTATGTTGGACGGCACCAGTTTGGGCATATGCACAGGCCAATCCATGGACAGAGGCAACAGCCAGACCTTTGGGAACTC
CCAGAACATAGGAGAACAGGGCTACTCCTCCACAAACTCCAGTGACAGCAGCTCTCAGCAGCTGGTGGCAAGCTCCTTGACCTCATCCTC
TACCCTGACAGAGATCCTGGAAGCCATGAAGCACCCCTCGACAGGAGTCCAGCTGCTCTCTGAACAGAAGGGCCTCTCACCGTACTGCTT
CATCAGCGCGGAGGTGGTACACTGGTTGGTGAACCACGTGGAGGGGATCCAGACACAGGCGATGGCCATTGACATCATGCAGAAAATGCT
GGAAGAGCAGCTCATCACACATGCATCTGGCGAAGCCTGGCGGACCTTCATCTACGGCTTCTATTTCTACAAGATAGTAACGGACAAAGA
GCCCGACCGAGCAGAAGAGCTCGTGCACTCTGAGATTCCTGCCTTTCTCCTGCCCTGGCTGCCTAGCCGGCCAGCCTCCTATGCAAGTAG
GCACAGCTCCTTTAGCCGAAGTTTTGGAGGACGGAGCCAGGCGGCAGCACTTTTAGGAAACCGTGAGGCAAGCCCGTCACCCCACACAGG
CTGCGGCATCACCCTCAGACCTTGGAGCCCAAGGGGCCACTGCCCTTGAAGTGGAGTGGGCCCAGAGTGTGGCGGTCCCCATGGTGGCAG
CCCCCCGACTGATCATCCAGACACAAAGGTCTTGGTTCTCCCAGGAGCTCAGGGCCTGTCAGACCTGGTGACAAGTGCCAAAGGCCACAG
GCATGAGGGAGGCGTGGACCACTGGGCCAGCACCGCTGAGTCCTAAGACTGCAGTCAAAGCCAGAACTGAGAGGGGACCCCAGACTGGGC
CCAGAGGCTGGCCAGAGTTCAGGAACGCCGGGCACAGACCAAAGACCGCGGTCCAGCCCCGCCCAGGCGGGCATCTCATGGCAGTGCGGA
CCCGTGGCTGGCAGCCCGGGCAGTCCTTTGCAAAGGCACCCCTTGTCTTAAAATCACTTCGCTATGTGGGAAAGGTGGAGATACTTTTAT
ATATTTGTATGGGACTCTGAGGAGGTGCAACCTGTATATATATTGCATTCGTGCTGACTTTGTTATCCCGAGAGATCCATGCAATGATCT
CTTGCTGTCTTCTCTGTCAAGATTGCACAGTTGTACTTGAATCTGGCATGTGTTGACGAAACTGGTGCCCCAGCAGATCAAAGGTGGGAA
ATACGTCAGCAGTGGGGCTAAAACCAAGCGGCTAGAAGCCCTACAGCTGCCTTCGGCCAGGAAGTGAGGATGGTGTGGGCCCTCCCCGCC
GGCCCCCTGGGTCCCCAGTGTTCGCTGTGTGTGCGTTTGTCCTCTGCTGCCATCTGCCCCGGCTGTGTGAATTCAAGACAGGGCAGTGCA
GCACTAGGCAGGTGTGAGGAGCCCTGCTGAGGTCACTGTGGGGCACGGTTGCCACACGGCTGTCATTTTTCACCTGGTCATTCTGTGACC
ACCACCCCCTCCCCTCACCGCCTCCCAGGTGGCCCGGGAGCTGCAGGTGGGGATGGCTTTGTCCTTTGCTCCTGCTCCCCGTGGGACCTG
GGACCTTAAAGCGTTGCAGGTTCCTGATTTGGACAGAGGTGTGGGGCCTTCCAGGCCGTTACATACCTCCTGCCAATTCTCTAACTCTCT
GAGACTGCGAGGATCTCCAGGCAGGGTTCTCCCCTCTGGAGTCTGACCAATTACTTCATTTTGCTTCAAATGGCCAATTGTGCAGAGGGA
CAAAGCCACAGCCACACTCTTCAACGGTTACCAAACTGTTTTTGGAAATTCACACCAAGGTCGGGCCCACTGCAGGCAGCTGGCACAGCG
TGGCCCGAGGGGCTGTGGAACGGGTCCCGGAACTGTCAGACATGTTTGATTTTAGCGTTTCCTTTGTTCTTCAAATCAGGTGCCCAAATA
AGTGATCAGCACAGCTGCTTCCAAATAGGAGAAACCATAAAATAGGATGAAAATCAAGTAAAATGCAAAGATGTCCACACTGTTTTAAAC
TTGACCCTGATGAAAATGTGAGCACTGTTAGCAGATGCCTATGGGAGAGGAAAAGCGTATCTGAAAATGGTCCAGGACAGGAGGATGAAA
TGAGATCCCAGAGTCCTCACACCTGAATGAATTATACATGTGCCTTACCAGGTGAGTGGTCTTTCGAAGATAAAAAACTCTAGTCCCTTT
AAACGTTTGCCCCTGGCGTTTCCTAAGTACGAAAAGGTTTTTAAGTCTTCGAACAGTCTCCTTTCATGACTTTAACAGGATTCTGCCCCC
TGAGGTGTAATTTTTTTGTTCTATTTTTTTCCACGTACTCCACAGCCAACATCACGAGGTGTAATTTTTAATTTGATCAGAACTGTTACC
AAAAAACAACTGTCAGTTTTATTGAGATGGGAAAAATGTAAACCTATTTTTATTACTTAAGACTTTATGGGAGAGATTAGACACTGGAGG
TTTTTAACAGAACGTGTATTTATTAATGTTCAAAACACTGGAATTACAAATGAGAAGAGTCTACAATAAATTAAGATTTTTGAATTTGTA
CTTCTGCGGTGCTGGTTTTTCTCCACAAACACCCCCGCCCCTCCCCATGCCCAGGGTGGCCGTGGAAGGGACGGTTTACGGACGTGCAGC
TGAGCTGTCCGTGTCCCATGCTCCCTCAGCCAGTGGAACGTGCCGGAACTTTTTGTCCATTCCCTAGTAGGCCTGCCACAGCCTAGATGG
GCAGTTTTTGTCTTTCACCAAATTTGAGGACTTTTTTTTTTTGCCATTATTTCTTCAGTTTTCTTTTCTTGCACTGATCTTTCTCCTCTC
CTTCTGTGACTCCAGTGACTCAGACGTTAGACCTCTTGATGTTTTCCCACTGGTCCCTGAGGCTCTGTTCGCATCTTGAAAAATAAAGTC
ACCTACCCGCCGCCGCTGACGCTGACGGAGCAGACGCTGAAGGGCCGGCTCCGGGAGAAGCTGGCCGACTGTGAGCAGAGCCCCACATCC
TCGCGCACGTCTTCCCTGGGCTCTGGCGGCCCCGACTGCGCCATCACAGTCAAGAGCCCTGGGAGGGAGCCGGGGCGTGACCACCTCAAC
GGGGTGGCCATGAATGTGCGCACTGGGAGCGCCCAGGCCGATGGCTCCGACTCTGAGGGACGCTGTGGCCAACCACGTTCCGGCCGGCTG
GCCCGACCAGAGCCTGGCTGAGAGTGACAGTGAGGACCCCAGCGGCAAGCCCCGCCTGAAGGTGGAGACCAAGGTCAGCGTGGAGCTGCA
CCGCGAGGAGCAGGGCAGTCACCGTGGAGAGTACCCCCCGGACCAGGAGAGCGGGGGCGCAGCCAGGCTTGCTAGCAGCCAGCCCCCAGA
GCAGAGGAAAGGCCACGATTCCGACTCAGATAGCGAGCTGTCCCTGGATGAGCAGAGCAGCTCTTACGCCTCCTCACACTCGTCAGACAG
CGAGGACGATGGGGTGGGAGCTGAGGAAAAATGGGACCCGGCCAGGGGCGCCGTCCACAGCACCCCCAAAGGGATGAAGGGATCCAGAAG
CTCGGCGTGTCCTCTGGGCTGGTGAGGGGCAGCCACGGAGAGCCAGACGCGTCCCTCATGCCCAGGAGCTGCAAGGATCCCCCTGCGCTC
CCTCAACTGCAACACCACCTTCGGTGACGGGCCTGACATGCTGCGCACAGACTTGGGCGAGTCCACCGCCTCGCTGGACAGCATCGTCAG
GGCCCCTTCGTCCTCCTTTTCCACTGCGTGCTCAACCAGGAGGTCCGGAAGCACCTGAAGGGCGTGCTCGGCGGGAGGAAGCTGCACCTG
GAGGACTCCGCCACCACCAGGGCCACCCTGCTGACGCTCCCTGCTGAGGACCGCATTCCTCCTGCTGCTGCTCATCAGCGCCACCTGGCT
GCTGGGGCTGCTGGCTGTGAACCGCGATGCACTGAGCTTTCACTACCTCTTCGCCATCTTCAGCGGCTTACAGATCAACACAGTCACTTC
TGTCCTATCTGCAAAGGTTTCCTGCCAAAGAAAGCACCATTATTATGGGAAAAAAGGGATCGTGACTGGCGGTCGGCCTGGACCCCCAGG
GCTACGGGAACCCCGACTTCTGCTGGCTGTCGCTTCAAGACACCCTGATTTGGAGCTTTGCGGGGCCCATCGGAGCTGTTATAATCTTTC
TGTGCACAGTGGTTGCCATCCTCCTCCACTACATCTACATGAGCACCTTTGCCTGGACCCTCGTGGAGAGCCTGCATGTCTACCGCATGC
TGACCGAGGTGCGCAACATCGACACGGGGCCCATGCGGTTCTACTACGTCGTGGGCTGGGGCATCCCGGCCATTGTCACAGAACGGGGAG
GTCCTGCCTCTGAAGATTGTCACCTATGCCGCTGTGTCCTTGTCACTGGCAGCCCTGCTGGTGGCCTTCGTCCTCCTGAGCCTGGTCCGC
ATGCTGCGCTCCAACCTGCACAGCATTCACAAGCACCTCGCCGTGGCGCTCTTCCTCTCTCAGCTGGTGTTCGTGATTGGGATCAACCAG
ACGGAAAACCCGCGTTGGTGGGACGGGAGGGTGGTCTGCCCGGGGCTGCGAGCTCCTGTCCAGGAACCGGACACATGTCGCCTGCCAGTG
CAGCCACACAGCCAGCTTTGCGGTGCTCATGGATATCTCCAGGCGTGAGGTTGCCTCACCGGCCCATCATTAATACCCCGATGGTGAGCA
CGCTGGTGTACAGCGAGGGGGCTCCGCTCCCGAGACCCCTGGAGAGGCCCGTCCTGGTGGAGTTCGCCCTGCTGGAGGTGGAGGAGCGAA
CCAAGCCTGTCTGCGTGTTCTGGAACCACTCCCTGGCAAGGCCCCCTGCTGAGGCCGGCTGGCCGGAGGACCACCCCGCAGACCACGCGC
CCGGGGCCTGGCACCGAGAGGGAGGCCCCGATCAGCAGGCGGAGGCGACACCCTGATGACGCTGGCCAGTTCGCCGTCGCTCTGGTCATC
ATTTACCGCACCCTGGGGCAGCTCCTGCCCGAGCGCTACGACCCCGACCGTCGCAGCCTCCGTTCTTGCTGTCGACATCTTTGACAAGTT
CAACTTTACGGGAGCCAGGGTCCCGCGATTCGACACCATCCATGAAGAGTTCCCCAGGGAGCTGGAGTCCTCCGTCTCCTTCCCAGCCGA
CTTCTTCAGACCACCTGAAGAAAAAGGACGTCATCCACTCGGGCAGCGCCCTCCTGGCCCCAGCCACCAGGGCGGCGTGGGAGCAGATCC
AGCGGAGCGAGGGCGGCACGGCACAGCTGCTCCGGCGCCTCGAGGGCTACTTCAGCAACGTGGCACGCAACGTGCGGCGGACGTACCTGC
GGCCCTTCGTCATCGTCACCGCCAACATGAAATGAGAAGCTGAGCCGCAATGAGACGCAGGTGGACGGCGCCAGGGCCCTGCAGCTGGTG
AGGGCGCTGCGCAGTGCTACACAGCACACGGGCACGCTCTTTGGCAATGACGTGCGCACGGCCTACCAGCTGCTGGGCCACGTCCTTCAG
CACGAGAGCTGGCAGCAGGGCTTCGACCTGGCAGCCACGCAGGACGCCGACTTTCACGAGGAAATGCGGTCCGACACTGCAGCGGGGAGA
AGGGCTGGCTGCCCCCAGAGCTCTTTAACTGTACCACCATCTCCTTCGTGGACCTCAGGGCCATGTGATCTACAATGGCTGTCCCAAAGC
ATTTGAGGCCGGCATCTGGTGGCCACAGACCAAGTTCGGGCAGCCGGCTGCGGTGCCATGCCCTAAGGGATCCGTTGGAGAATTACTACA
AGCTCCTAGCCCAGGACACCTGTCTGCCCTGCGACTGCTTCCCCCATGGCTCCCACAGCCGCACTTGCGACATGGCCACCGGGCAGTGTG
CCTGCAAGCCCGGCGTCATCGGCCGCCAGTGCAACCGCTGCGACAACCCGTTTGCCGAGGTCACCACGCTCGGCTGTGAAGACTCGACCT
TCCGTGCCCCAGAGGCTGGTGGGGGAACCCCGTCTGTGGACCCTGCCACTGTGCCGTCAGCAAAGGCTTTGATCCCGACTGTAATAAGAC
CAACGGCCAGTGCCAATGCAAGCTGTGTGGATGCCTGTCACCTGAACCCCTGCGAGAACATGGGGGCCTGCGTGCGCTCCCCCGGCTCCC

>22311_22311_1_DEPDC5-CELSR1_DEPDC5_chr22_32275603_ENST00000266091_CELSR1_chr22_46792627_ENST00000262738_length(amino acids)=1318AA_BP=1284
MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKEDLQKETISVDQTVTQVFRLRPYQDVYVNVV
DPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRASIRQDHKGRFYEDFYKVVVQNERREEWTSL
LVTIKKLFIQYPVLVRLEQAEGFPQGDNSTSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFTPRIKLAGKKPASEKAKNGRDTSLGSPKESE
NALPIQVDYDAYDAQVFRLPGPSRAQCLTTCRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAI
QIHHQTRQNMAELQGSGQRDPTHSSAELLELAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
PDPILTLSAPPVVPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDEDGVQMTAQQVFEEFICQRLMQG
YQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSE
FVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIYGDRPRADEDEWQLLDGFVRFV
EGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTP
TYMDSPRKVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSSSQQLVASSLTSSSTLTEILEAMKHPSTGVQ
LLSEQKGLSPYCFISAEVVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRAEELVHSEIPAFLL

--------------------------------------------------------------
>22311_22311_2_DEPDC5-CELSR1_DEPDC5_chr22_32275603_ENST00000382111_CELSR1_chr22_46792627_ENST00000262738_length(transcript)=9672nt_BP=4000nt
GGAGGCAAGATGACTTCTCTGCCCCAAGCTTGGAACAGCTAAAGGGAAAAACAGTGCAAGATGAGAACAACAAAGGTCTACAAACTCGTC
ATCCACAAGAAGGGCTTTGGGGGCAGTGATGATGAGCTAGTTGTGAACCCCAAAGTGTTCCCTCACATCAAGCTTGGAGACATTGTAGAG
ATTGCACACCCCAACGATGAATACAGCCCTCTGCTTTTGCAGGTCAAGTCTCTTAAGGAAGATTTACAGAAGGAAACTATCAGTGTGGAC
CAGACTGTGACTCAAGTGTTCCGGCTGAGACCTTATCAGGATGTCTATGTTAATGTCGTAGACCCTAAGGATGTGACCCTTGACCTAGTG
GAATTAACTTTTAAGGATCAGTATATTGGCCGTGGGGATATGTGGCGACTAAAGAAAAGTTTGGTCAGCACATGTGCCTATATCACCCAG
AAGGTGGAGTTTGCTGGCATCAGAGCACAGGCTGGTGAACTGTGGGTTAAGAATGAGAAGGTCATGTGTGGCTACATCAGTGAAGATACC
AGGGTGGTGTTTCGTTCTACGTCGGCTATGGTTTACATATTTATTCAGATGAGCTGTGAAATGTGGGATTTTGATATTTATGGGGATTTG
TATTTTGAGAAAGCTGTGAATGGTTTCCTTGCTGATCTATTTACCAAGTGGAAGGAGAAGAACTGTAGTCATGAAGTGACAGTGGTCCTG
TTTTCTAGAACTTTCTATGATGCAAAATCTGTTGATGAATTTCCTGAAATAAACCGAGCCTCAATTCGACAGGATCACAAGGGGAGATTC
TATGAAGACTTTTACAAAGTGGTGGTGCAGAATGAGAGAAGAGAAGAATGGACTTCACTTCTCGTAACCATTAAAAAACTCTTCATCCAG
TATCCAGTGTTGGTGCGACTGGAACAGGCAGAGGGCTTTCCTCAAGGAGATAATTCTACCTCAGCACAAGGAAACTACCTGGAGGCCATC
AATCTGTCATTCAATGTGTTTGATAAGCACTACATCAACCGCAACTTTGACCGAACTGGGCAGATGTCAGTGGTGATCACGCCCGGGGTG
GGTGTCTTTGAAGTGGACCGCCTACTCATGATCCTGACCAAGCAGCGGATGATAGATAATGGAATTGGTGTGGATTTGGTGTGCATGGGA
GAGCAACCGTTACATGCTGTCCCATTGTTCAAGCTCCATAATCGGAGTGCTCCCCGTGATTCTCGTCTGGGCGATGACTATAATATCCCT
CACTGGATAAACCACAGTTTCTACACATCCAAAAGCCAGCTCTTTTGTAATAGTTTCACCCCACGAATAAAACTGGCAGGAAAGAAGCCC
GCCTCTGAGAAAGCAAAAAATGGCCGTGATACATCTCTCGGGAGTCCAAAAGAATCTGAGAACGCCCTTCCCATCCAAGTAGATTATGAC
GCCTATGACGCTCAAGTGTTCAGGCTGCCCGGCCCATCCCGGGCCCAGTGCCTCACCACCTGCAGATCTGTGCGAGAGCGAGAGAGTCAC
AGTCGAAAGAGTGCCAGCTCCTGTGATGTTTCATCCAGCCCTTCCCTACCAAGCCGCACACTGCCCACTGAGGAAGTGAGGAGCCAGGCT
TCTGACGACAGCTCCCTAGGCAAGAGTGCCAACATCCTGATGATCCCACACCCCCACCTGCACCAGTATGAAGTCAGCAGCTCCTTGGGA
TACACCAGCACTCGAGATGTCCTGGAGAACATGATGGAGCCACCACAGCGAGACTCCAGTGCACCAGGGAGGTTTCACGTTGGCAGTGCA
GAATCCATGCTGCATGTTCGACCTGGTGGATACACGCCCCAGAGAGCACTGATTAACCCCTTCGCTCCCTCTCGGATGCCCATGAAGCTT
ACGTCCAACAGAAGGCGCTGGATGCACACTTTTCCTGTGGGGCCATCCGGAGAAGCCATCCAGATCCACCACCAGACCCGACAGAATATG
GCGGAGCTACAAGGCAGCGGGCAGAGGGATCCAACTCACTCCTCTGCAGAGCTGCTGGAGTTAGCATATCATGAAGCTGCTGGAAGGCAC
AGCAATTCCCGCCAGCCTGGTGACGGCATGTCCTTCTTGAACTTCAGTGGAACAGAGGAGCTTTCTGTCGGCCTGCTTAGCAACAGTGGT
GCAGGTATGAATCCTAGGACCCAGAATAAGGATTCTCTAGAGGACAGTGTTTCTACCTCTCCAGACCCAATTCTGACACTGTCTGCTCCC
CCTGTAGTGCCAGGCTTCTGTTGCACAGTTGGAGTGGACTGGAAGTCTCTCACTACTCCGGCGTGCCTCCCCCTTACCACCGACTACTTC
CCTGACCGCCAGGGCCTGCAGAATGACTACACAGAGGGCTGTTATGATCTCCTTCCAGAAGCAGACATCGACAGGAGGGACGAAGATGGT
GTGCAGATGACAGCCCAGCAGGTATTTGAAGAGTTTATTTGCCAACGTCTCATGCAGGGCTACCAAATCATAGTGCAGCCCAAGACACAG
AAACCCAATCCTGCTGTCCCGCCCCCGCTGAGCAGTAGCCCACTCTATAGCCGAGGCCTTGTGTCCCGAAACCGCCCTGAGGAGGAGGAC
CAGTATTGGCTGAGTATGGGCAGAACGTTCCACAAAGTGACGCTGAAGGATAAGATGATCACAGTGACGCGATACCTTCCCAAGTATCCT
TATGAATCTGCCCAGATCCACTACACCTACAGCCTCTGTCCTTCCCACTCAGACTCAGAGTTCGTCTCCTGCTGGGTGGAATTCTCCCAC
GAACGGCTGGAGGAGTACAAGTGGAATTACTTAGATCAGTATATCTGTTCTGCCGGCTCTGAAGACTTCAGCTTAATTGAGTCCCTGAAG
TTCTGGAGGACCCGCTTCCTGCTGCTGCCAGCCTGTGTCACCGCCACCAAGCGCATCACGGAGGGGGAGGCCCACTGCGACATCTATGGG
GACAGGCCCCGTGCAGACGAGGACGAGTGGCAACTCCTGGATGGTTTTGTCCGCTTTGTGGAGGGCTTGAATCGCATTCGCAGGCGGCAT
CGCTCGGATCGCATGATGCGGAAAGGGACCGCCATGAAAGGCTTGCAGATGACTGGGCCCATTTCCACGCATTCTCTGGAGTCAACTGCA
CCCCCAGTGGGGAAGAAGGGAACCTCAGCTCTCTCTGCCCTGTTGGAGATGGAGGCCAGTCAGAAGTGCCTGGGAGAACAGCAGGCAGCT
GTGCATGGTGGGAAGAGCTCCGCCCAGTCAGCCGAGAGCAGCAGCGTTGCCATGACTCCCACCTACATGGACAGCCCACGAAAGGACGGG
GCCTTCTTTATGGAGTTTGTCCGCAGCCCACGCACAGCATCGTCCGCCTTCTACCCTCAGGTATCTGTGGACCAAACAGCCACTCCTATG
TTGGACGGCACCAGTTTGGGCATATGCACAGGCCAATCCATGGACAGAGGCAACAGCCAGACCTTTGGGAACTCCCAGAACATAGGAGAA
CAGGGCTACTCCTCCACAAACTCCAGTGACAGCAGCTCTCAGCAGCTGGTGGCAAGCTCCTTGACCTCATCCTCTACCCTGACAGAGATC
CTGGAAGCCATGAAGCACCCCTCGACAGGAGTCCAGCTGCTCTCTGAACAGAAGGGCCTCTCACCGTACTGCTTCATCAGCGCGGAGGTG
GTACACTGGTTGGTGAACCACGTGGAGGGGATCCAGACACAGGCGATGGCCATTGACATCATGCAGAAAATGCTGGAAGAGCAGCTCATC
ACACATGCATCTGGCGAAGCCTGGCGGACCTTCATCTACGGCTTCTATTTCTACAAGATAGTAACGGACAAAGAGCCCGACCGAGCAGAA
GAGCTCGTGCACTCTGAGATTCCTGCCTTTCTCCTGCCCTGGCTGCCTAGCCGGCCAGCCTCCTATGCAAGTAGGCACAGCTCCTTTAGC
CGAAGTTTTGGAGGACGGAGCCAGGCGGCAGCACTTTTAGGAAACCGTGAGGCAAGCCCGTCACCCCACACAGGCTGCGGCATCACCCTC
AGACCTTGGAGCCCAAGGGGCCACTGCCCTTGAAGTGGAGTGGGCCCAGAGTGTGGCGGTCCCCATGGTGGCAGCCCCCCGACTGATCAT
CCAGACACAAAGGTCTTGGTTCTCCCAGGAGCTCAGGGCCTGTCAGACCTGGTGACAAGTGCCAAAGGCCACAGGCATGAGGGAGGCGTG
GACCACTGGGCCAGCACCGCTGAGTCCTAAGACTGCAGTCAAAGCCAGAACTGAGAGGGGACCCCAGACTGGGCCCAGAGGCTGGCCAGA
GTTCAGGAACGCCGGGCACAGACCAAAGACCGCGGTCCAGCCCCGCCCAGGCGGGCATCTCATGGCAGTGCGGACCCGTGGCTGGCAGCC
CGGGCAGTCCTTTGCAAAGGCACCCCTTGTCTTAAAATCACTTCGCTATGTGGGAAAGGTGGAGATACTTTTATATATTTGTATGGGACT
CTGAGGAGGTGCAACCTGTATATATATTGCATTCGTGCTGACTTTGTTATCCCGAGAGATCCATGCAATGATCTCTTGCTGTCTTCTCTG
TCAAGATTGCACAGTTGTACTTGAATCTGGCATGTGTTGACGAAACTGGTGCCCCAGCAGATCAAAGGTGGGAAATACGTCAGCAGTGGG
GCTAAAACCAAGCGGCTAGAAGCCCTACAGCTGCCTTCGGCCAGGAAGTGAGGATGGTGTGGGCCCTCCCCGCCGGCCCCCTGGGTCCCC
AGTGTTCGCTGTGTGTGCGTTTGTCCTCTGCTGCCATCTGCCCCGGCTGTGTGAATTCAAGACAGGGCAGTGCAGCACTAGGCAGGTGTG
AGGAGCCCTGCTGAGGTCACTGTGGGGCACGGTTGCCACACGGCTGTCATTTTTCACCTGGTCATTCTGTGACCACCACCCCCTCCCCTC
ACCGCCTCCCAGGTGGCCCGGGAGCTGCAGGTGGGGATGGCTTTGTCCTTTGCTCCTGCTCCCCGTGGGACCTGGGACCTTAAAGCGTTG
CAGGTTCCTGATTTGGACAGAGGTGTGGGGCCTTCCAGGCCGTTACATACCTCCTGCCAATTCTCTAACTCTCTGAGACTGCGAGGATCT
CCAGGCAGGGTTCTCCCCTCTGGAGTCTGACCAATTACTTCATTTTGCTTCAAATGGCCAATTGTGCAGAGGGACAAAGCCACAGCCACA
CTCTTCAACGGTTACCAAACTGTTTTTGGAAATTCACACCAAGGTCGGGCCCACTGCAGGCAGCTGGCACAGCGTGGCCCGAGGGGCTGT
GGAACGGGTCCCGGAACTGTCAGACATGTTTGATTTTAGCGTTTCCTTTGTTCTTCAAATCAGGTGCCCAAATAAGTGATCAGCACAGCT
GCTTCCAAATAGGAGAAACCATAAAATAGGATGAAAATCAAGTAAAATGCAAAGATGTCCACACTGTTTTAAACTTGACCCTGATGAAAA
TGTGAGCACTGTTAGCAGATGCCTATGGGAGAGGAAAAGCGTATCTGAAAATGGTCCAGGACAGGAGGATGAAATGAGATCCCAGAGTCC
TCACACCTGAATGAATTATACATGTGCCTTACCAGGTGAGTGGTCTTTCGAAGATAAAAAACTCTAGTCCCTTTAAACGTTTGCCCCTGG
CGTTTCCTAAGTACGAAAAGGTTTTTAAGTCTTCGAACAGTCTCCTTTCATGACTTTAACAGGATTCTGCCCCCTGAGGTGTAATTTTTT
TGTTCTATTTTTTTCCACGTACTCCACAGCCAACATCACGAGGTGTAATTTTTAATTTGATCAGAACTGTTACCAAAAAACAACTGTCAG
TTTTATTGAGATGGGAAAAATGTAAACCTATTTTTATTACTTAAGACTTTATGGGAGAGATTAGACACTGGAGGTTTTTAACAGAACGTG
TATTTATTAATGTTCAAAACACTGGAATTACAAATGAGAAGAGTCTACAATAAATTAAGATTTTTGAATTTGTACTTCTGCGGTGCTGGT
TTTTCTCCACAAACACCCCCGCCCCTCCCCATGCCCAGGGTGGCCGTGGAAGGGACGGTTTACGGACGTGCAGCTGAGCTGTCCGTGTCC
CATGCTCCCTCAGCCAGTGGAACGTGCCGGAACTTTTTGTCCATTCCCTAGTAGGCCTGCCACAGCCTAGATGGGCAGTTTTTGTCTTTC
ACCAAATTTGAGGACTTTTTTTTTTTGCCATTATTTCTTCAGTTTTCTTTTCTTGCACTGATCTTTCTCCTCTCCTTCTGTGACTCCAGT
GACTCAGACGTTAGACCTCTTGATGTTTTCCCACTGGTCCCTGAGGCTCTGTTCGCATCTTGAAAAATAAAGTCACCTACCCGCCGCCGC
TGACGCTGACGGAGCAGACGCTGAAGGGCCGGCTCCGGGAGAAGCTGGCCGACTGTGAGCAGAGCCCCACATCCTCGCGCACGTCTTCCC
TGGGCTCTGGCGGCCCCGACTGCGCCATCACAGTCAAGAGCCCTGGGAGGGAGCCGGGGCGTGACCACCTCAACGGGGTGGCCATGAATG
TGCGCACTGGGAGCGCCCAGGCCGATGGCTCCGACTCTGAGGGACGCTGTGGCCAACCACGTTCCGGCCGGCTGGCCCGACCAGAGCCTG
GCTGAGAGTGACAGTGAGGACCCCAGCGGCAAGCCCCGCCTGAAGGTGGAGACCAAGGTCAGCGTGGAGCTGCACCGCGAGGAGCAGGGC
AGTCACCGTGGAGAGTACCCCCCGGACCAGGAGAGCGGGGGCGCAGCCAGGCTTGCTAGCAGCCAGCCCCCAGAGCAGAGGAAAGGCCAC
GATTCCGACTCAGATAGCGAGCTGTCCCTGGATGAGCAGAGCAGCTCTTACGCCTCCTCACACTCGTCAGACAGCGAGGACGATGGGGTG
GGAGCTGAGGAAAAATGGGACCCGGCCAGGGGCGCCGTCCACAGCACCCCCAAAGGGATGAAGGGATCCAGAAGCTCGGCGTGTCCTCTG
GGCTGGTGAGGGGCAGCCACGGAGAGCCAGACGCGTCCCTCATGCCCAGGAGCTGCAAGGATCCCCCTGCGCTCCCTCAACTGCAACACC
ACCTTCGGTGACGGGCCTGACATGCTGCGCACAGACTTGGGCGAGTCCACCGCCTCGCTGGACAGCATCGTCAGGGCCCCTTCGTCCTCC
TTTTCCACTGCGTGCTCAACCAGGAGGTCCGGAAGCACCTGAAGGGCGTGCTCGGCGGGAGGAAGCTGCACCTGGAGGACTCCGCCACCA
CCAGGGCCACCCTGCTGACGCTCCCTGCTGAGGACCGCATTCCTCCTGCTGCTGCTCATCAGCGCCACCTGGCTGCTGGGGCTGCTGGCT
GTGAACCGCGATGCACTGAGCTTTCACTACCTCTTCGCCATCTTCAGCGGCTTACAGATCAACACAGTCACTTCTGTCCTATCTGCAAAG
GTTTCCTGCCAAAGAAAGCACCATTATTATGGGAAAAAAGGGATCGTGACTGGCGGTCGGCCTGGACCCCCAGGGCTACGGGAACCCCGA
CTTCTGCTGGCTGTCGCTTCAAGACACCCTGATTTGGAGCTTTGCGGGGCCCATCGGAGCTGTTATAATCTTTCTGTGCACAGTGGTTGC
CATCCTCCTCCACTACATCTACATGAGCACCTTTGCCTGGACCCTCGTGGAGAGCCTGCATGTCTACCGCATGCTGACCGAGGTGCGCAA
CATCGACACGGGGCCCATGCGGTTCTACTACGTCGTGGGCTGGGGCATCCCGGCCATTGTCACAGAACGGGGAGGTCCTGCCTCTGAAGA
TTGTCACCTATGCCGCTGTGTCCTTGTCACTGGCAGCCCTGCTGGTGGCCTTCGTCCTCCTGAGCCTGGTCCGCATGCTGCGCTCCAACC
TGCACAGCATTCACAAGCACCTCGCCGTGGCGCTCTTCCTCTCTCAGCTGGTGTTCGTGATTGGGATCAACCAGACGGAAAACCCGCGTT
GGTGGGACGGGAGGGTGGTCTGCCCGGGGCTGCGAGCTCCTGTCCAGGAACCGGACACATGTCGCCTGCCAGTGCAGCCACACAGCCAGC
TTTGCGGTGCTCATGGATATCTCCAGGCGTGAGGTTGCCTCACCGGCCCATCATTAATACCCCGATGGTGAGCACGCTGGTGTACAGCGA
GGGGGCTCCGCTCCCGAGACCCCTGGAGAGGCCCGTCCTGGTGGAGTTCGCCCTGCTGGAGGTGGAGGAGCGAACCAAGCCTGTCTGCGT
GTTCTGGAACCACTCCCTGGCAAGGCCCCCTGCTGAGGCCGGCTGGCCGGAGGACCACCCCGCAGACCACGCGCCCGGGGCCTGGCACCG
AGAGGGAGGCCCCGATCAGCAGGCGGAGGCGACACCCTGATGACGCTGGCCAGTTCGCCGTCGCTCTGGTCATCATTTACCGCACCCTGG
GGCAGCTCCTGCCCGAGCGCTACGACCCCGACCGTCGCAGCCTCCGTTCTTGCTGTCGACATCTTTGACAAGTTCAACTTTACGGGAGCC
AGGGTCCCGCGATTCGACACCATCCATGAAGAGTTCCCCAGGGAGCTGGAGTCCTCCGTCTCCTTCCCAGCCGACTTCTTCAGACCACCT
GAAGAAAAAGGACGTCATCCACTCGGGCAGCGCCCTCCTGGCCCCAGCCACCAGGGCGGCGTGGGAGCAGATCCAGCGGAGCGAGGGCGG
CACGGCACAGCTGCTCCGGCGCCTCGAGGGCTACTTCAGCAACGTGGCACGCAACGTGCGGCGGACGTACCTGCGGCCCTTCGTCATCGT
CACCGCCAACATGAAATGAGAAGCTGAGCCGCAATGAGACGCAGGTGGACGGCGCCAGGGCCCTGCAGCTGGTGAGGGCGCTGCGCAGTG
CTACACAGCACACGGGCACGCTCTTTGGCAATGACGTGCGCACGGCCTACCAGCTGCTGGGCCACGTCCTTCAGCACGAGAGCTGGCAGC
AGGGCTTCGACCTGGCAGCCACGCAGGACGCCGACTTTCACGAGGAAATGCGGTCCGACACTGCAGCGGGGAGAAGGGCTGGCTGCCCCC
AGAGCTCTTTAACTGTACCACCATCTCCTTCGTGGACCTCAGGGCCATGTGATCTACAATGGCTGTCCCAAAGCATTTGAGGCCGGCATC
TGGTGGCCACAGACCAAGTTCGGGCAGCCGGCTGCGGTGCCATGCCCTAAGGGATCCGTTGGAGAATTACTACAAGCTCCTAGCCCAGGA
CACCTGTCTGCCCTGCGACTGCTTCCCCCATGGCTCCCACAGCCGCACTTGCGACATGGCCACCGGGCAGTGTGCCTGCAAGCCCGGCGT
CATCGGCCGCCAGTGCAACCGCTGCGACAACCCGTTTGCCGAGGTCACCACGCTCGGCTGTGAAGACTCGACCTTCCGTGCCCCAGAGGC
TGGTGGGGGAACCCCGTCTGTGGACCCTGCCACTGTGCCGTCAGCAAAGGCTTTGATCCCGACTGTAATAAGACCAACGGCCAGTGCCAA
TGCAAGCTGTGTGGATGCCTGTCACCTGAACCCCTGCGAGAACATGGGGGCCTGCGTGCGCTCCCCCGGCTCCCCGCAGGGCTACGTGTG

>22311_22311_2_DEPDC5-CELSR1_DEPDC5_chr22_32275603_ENST00000382111_CELSR1_chr22_46792627_ENST00000262738_length(amino acids)=1340AA_BP=1306
MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKEDLQKETISVDQTVTQVFRLRPYQDVYVNVV
DPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRASIRQDHKGRFYEDFYKVVVQNERREEWTSL
LVTIKKLFIQYPVLVRLEQAEGFPQGDNSTSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFTPRIKLAGKKPASEKAKNGRDTSLGSPKESE
NALPIQVDYDAYDAQVFRLPGPSRAQCLTTCRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAI
QIHHQTRQNMAELQGSGQRDPTHSSAELLELAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
PDPILTLSAPPVVPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDEDGVQMTAQQVFEEFICQRLMQG
YQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSE
FVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIYGDRPRADEDEWQLLDGFVRFV
EGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTP
TYMDSPRKDGAFFMEFVRSPRTASSAFYPQVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSSSQQLVASS
LTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKI

--------------------------------------------------------------
>22311_22311_3_DEPDC5-CELSR1_DEPDC5_chr22_32275603_ENST00000382112_CELSR1_chr22_46792627_ENST00000262738_length(transcript)=9655nt_BP=3983nt
TCTGTGGCAGGGAGGCAAGATGACTTCTCTGCCCCAAGCTTGGAACAGCTAAAGGGAAAAACAGTGCAAGATGAGAACAACAAAGGTCTA
CAAACTCGTCATCCACAAGAAGGGCTTTGGGGGCAGTGATGATGAGCTAGTTGTGAACCCCAAAGTGTTCCCTCACATCAAGCTTGGAGA
CATTGTAGAGATTGCACACCCCAACGATGAATACAGCCCTCTGCTTTTGCAGGTCAAGTCTCTTAAGGAAGATTTACAGAAGGAAACTAT
CAGTGTGGACCAGACTGTGACTCAAGTGTTCCGGCTGAGACCTTATCAGGATGTCTATGTTAATGTCGTAGACCCTAAGGATGTGACCCT
TGACCTAGTGGAATTAACTTTTAAGGATCAGTATATTGGCCGTGGGGATATGTGGCGACTAAAGAAAAGTTTGGTCAGCACATGTGCCTA
TATCACCCAGAAGGTGGAGTTTGCTGGCATCAGAGCACAGGCTGGTGAACTGTGGGTTAAGAATGAGAAGGTCATGTGTGGCTACATCAG
TGAAGATACCAGGGTGGTGTTTCGTTCTACGTCGGCTATGGTTTACATATTTATTCAGATGAGCTGTGAAATGTGGGATTTTGATATTTA
TGGGGATTTGTATTTTGAGAAAGCTGTGAATGGTTTCCTTGCTGATCTATTTACCAAGTGGAAGGAGAAGAACTGTAGTCATGAAGTGAC
AGTGGTCCTGTTTTCTAGAACTTTCTATGATGCAAAATCTGTTGATGAATTTCCTGAAATAAACCGAGCCTCAATTCGACAGGATCACAA
GGGGAGATTCTATGAAGACTTTTACAAAGTGGTGGTGCAGAATGAGAGAAGAGAAGAATGGACTTCACTTCTCGTAACCATTAAAAAACT
CTTCATCCAGTATCCAGTGTTGGTGCGACTGGAACAGGCAGAGGGCTTTCCTCAAGGAGATAATTCTACCTCAGCACAAGGAAACTACCT
GGAGGCCATCAATCTGTCATTCAATGTGTTTGATAAGCACTACATCAACCGCAACTTTGACCGAACTGGGCAGATGTCAGTGGTGATCAC
GCCCGGGGTGGGTGTCTTTGAAGTGGACCGCCTACTCATGATCCTGACCAAGCAGCGGATGATAGATAATGGAATTGGTGTGGATTTGGT
GTGCATGGGAGAGCAACCGTTACATGCTGTCCCATTGTTCAAGCTCCATAATCGGAGTGCTCCCCGTGATTCTCGTCTGGGCGATGACTA
TAATATCCCTCACTGGATAAACCACAGTTTCTACACATCCAAAAGCCAGCTCTTTTGTAATAGTTTCACCCCACGAATAAAACTGGCAGG
AAAGAAGCCCGCCTCTGAGAAAGCAAAAAATGGCCGTGATACATCTCTCGGGAGTCCAAAAGAATCTGAGAACGCCCTTCCCATCCAAGT
AGATTATGACGCCTATGACGCTCAAGTGTTCAGGCTGCCCGGCCCATCCCGGGCCCAGTGCCTCACCACCTGCAGATCTGTGCGAGAGCG
AGAGAGTCACAGTCGAAAGAGTGCCAGCTCCTGTGATGTTTCATCCAGCCCTTCCCTACCAAGCCGCACACTGCCCACTGAGGAAGTGAG
GAGCCAGGCTTCTGACGACAGCTCCCTAGGCAAGAGTGCCAACATCCTGATGATCCCACACCCCCACCTGCACCAGTATGAAGTCAGCAG
CTCCTTGGGATACACCAGCACTCGAGATGTCCTGGAGAACATGATGGAGCCACCACAGCGAGACTCCAGTGCACCAGGGAGGTTTCACGT
TGGCAGTGCAGAATCCATGCTGCATGTTCGACCTGGTGGATACACGCCCCAGAGAGCACTGATTAACCCCTTCGCTCCCTCTCGGATGCC
CATGAAGCTTACGTCCAACAGAAGGCGCTGGATGCACACTTTTCCTGTGGGGCCATCCGGAGAAGCCATCCAGATCCACCACCAGACCCG
ACAGAATATGGCGGAGCTACAAGGCAGCGGGCAGAGGGATCCAACTCACTCCTCTGCAGAGCTGCTGGAGTTAGCATATCATGAAGCTGC
TGGAAGGCACAGCAATTCCCGCCAGCCTGGTGACGGCATGTCCTTCTTGAACTTCAGTGGAACAGAGGAGCTTTCTGTCGGCCTGCTTAG
CAACAGTGGTGCAGGTATGAATCCTAGGACCCAGAATAAGGATTCTCTAGAGGACAGTGTTTCTACCTCTCCAGACCCAATGCCAGGCTT
CTGTTGCACAGTTGGAGTGGACTGGAAGTCTCTCACTACTCCGGCGTGCCTCCCCCTTACCACCGACTACTTCCCTGACCGCCAGGGCCT
GCAGAATGACTACACAGAGGGCTGTTATGATCTCCTTCCAGAAGCAGACATCGACAGGAGGGACGAAGATGGTGTGCAGATGACAGCCCA
GCAGGTATTTGAAGAGTTTATTTGCCAACGTCTCATGCAGGGCTACCAAATCATAGTGCAGCCCAAGACACAGAAACCCAATCCTGCTGT
CCCGCCCCCGCTGAGCAGTAGCCCACTCTATAGCCGAGGCCTTGTGTCCCGAAACCGCCCTGAGGAGGAGGACCAGTATTGGCTGAGTAT
GGGCAGAACGTTCCACAAAGTGACGCTGAAGGATAAGATGATCACAGTGACGCGATACCTTCCCAAGTATCCTTATGAATCTGCCCAGAT
CCACTACACCTACAGCCTCTGTCCTTCCCACTCAGACTCAGAGTTCGTCTCCTGCTGGGTGGAATTCTCCCACGAACGGCTGGAGGAGTA
CAAGTGGAATTACTTAGATCAGTATATCTGTTCTGCCGGCTCTGAAGACTTCAGCTTAATTGAGTCCCTGAAGTTCTGGAGGACCCGCTT
CCTGCTGCTGCCAGCCTGTGTCACCGCCACCAAGCGCATCACGGAGGGGGAGGCCCACTGCGACATCTATGGGGACAGGCCCCGTGCAGA
CGAGGACGAGTGGCAACTCCTGGATGGTTTTGTCCGCTTTGTGGAGGGCTTGAATCGCATTCGCAGGCGGCATCGCTCGGATCGCATGAT
GCGGAAAGGGACCGCCATGAAAGGCTTGCAGATGACTGGGCCCATTTCCACGCATTCTCTGGAGTCAACTGCACCCCCAGTGGGGAAGAA
GGGAACCTCAGCTCTCTCTGCCCTGTTGGAGATGGAGGCCAGTCAGAAGTGCCTGGGAGAACAGCAGGCAGCTGTGCATGGTGGGAAGAG
CTCCGCCCAGTCAGCCGAGAGCAGCAGCGTTGCCATGACTCCCACCTACATGGACAGCCCACGAAAGGACGGGGCCTTCTTTATGGAGTT
TGTCCGCAGCCCACGCACAGCATCGTCCGCCTTCTACCCTCAGGTATCTGTGGACCAAACAGCCACTCCTATGTTGGACGGCACCAGTTT
GGGCATATGCACAGGCCAATCCATGGACAGAGGCAACAGCCAGACCTTTGGGAACTCCCAGAACATAGGAGAACAGGGCTACTCCTCCAC
AAACTCCAGTGACAGCAGCTCTCAGCAGCTGGTGGCAAGCTCCTTGACCTCATCCTCTACCCTGACAGAGATCCTGGAAGCCATGAAGCA
CCCCTCGACAGGAGTCCAGCTGCTCTCTGAACAGAAGGGCCTCTCACCGTACTGCTTCATCAGCGCGGAGGTGGTACACTGGTTGGTGAA
CCACGTGGAGGGGATCCAGACACAGGCGATGGCCATTGACATCATGCAGAAAATGCTGGAAGAGCAGCTCATCACACATGCATCTGGCGA
AGCCTGGCGGACCTTCATCTACGGCTTCTATTTCTACAAGATAGTAACGGACAAAGAGCCCGACCGAGCAGAAGAGCTCGTGCACTCTGA
GATTCCTGCCTTTCTCCTGCCCTGGCTGCCTAGCCGGCCAGCCTCCTATGCAAGTAGGCACAGCTCCTTTAGCCGAAGTTTTGGAGGACG
GAGCCAGGCGGCAGCACTTTTAGGAAACCGTGAGGCAAGCCCGTCACCCCACACAGGCTGCGGCATCACCCTCAGACCTTGGAGCCCAAG
GGGCCACTGCCCTTGAAGTGGAGTGGGCCCAGAGTGTGGCGGTCCCCATGGTGGCAGCCCCCCGACTGATCATCCAGACACAAAGGTCTT
GGTTCTCCCAGGAGCTCAGGGCCTGTCAGACCTGGTGACAAGTGCCAAAGGCCACAGGCATGAGGGAGGCGTGGACCACTGGGCCAGCAC
CGCTGAGTCCTAAGACTGCAGTCAAAGCCAGAACTGAGAGGGGACCCCAGACTGGGCCCAGAGGCTGGCCAGAGTTCAGGAACGCCGGGC
ACAGACCAAAGACCGCGGTCCAGCCCCGCCCAGGCGGGCATCTCATGGCAGTGCGGACCCGTGGCTGGCAGCCCGGGCAGTCCTTTGCAA
AGGCACCCCTTGTCTTAAAATCACTTCGCTATGTGGGAAAGGTGGAGATACTTTTATATATTTGTATGGGACTCTGAGGAGGTGCAACCT
GTATATATATTGCATTCGTGCTGACTTTGTTATCCCGAGAGATCCATGCAATGATCTCTTGCTGTCTTCTCTGTCAAGATTGCACAGTTG
TACTTGAATCTGGCATGTGTTGACGAAACTGGTGCCCCAGCAGATCAAAGGTGGGAAATACGTCAGCAGTGGGGCTAAAACCAAGCGGCT
AGAAGCCCTACAGCTGCCTTCGGCCAGGAAGTGAGGATGGTGTGGGCCCTCCCCGCCGGCCCCCTGGGTCCCCAGTGTTCGCTGTGTGTG
CGTTTGTCCTCTGCTGCCATCTGCCCCGGCTGTGTGAATTCAAGACAGGGCAGTGCAGCACTAGGCAGGTGTGAGGAGCCCTGCTGAGGT
CACTGTGGGGCACGGTTGCCACACGGCTGTCATTTTTCACCTGGTCATTCTGTGACCACCACCCCCTCCCCTCACCGCCTCCCAGGTGGC
CCGGGAGCTGCAGGTGGGGATGGCTTTGTCCTTTGCTCCTGCTCCCCGTGGGACCTGGGACCTTAAAGCGTTGCAGGTTCCTGATTTGGA
CAGAGGTGTGGGGCCTTCCAGGCCGTTACATACCTCCTGCCAATTCTCTAACTCTCTGAGACTGCGAGGATCTCCAGGCAGGGTTCTCCC
CTCTGGAGTCTGACCAATTACTTCATTTTGCTTCAAATGGCCAATTGTGCAGAGGGACAAAGCCACAGCCACACTCTTCAACGGTTACCA
AACTGTTTTTGGAAATTCACACCAAGGTCGGGCCCACTGCAGGCAGCTGGCACAGCGTGGCCCGAGGGGCTGTGGAACGGGTCCCGGAAC
TGTCAGACATGTTTGATTTTAGCGTTTCCTTTGTTCTTCAAATCAGGTGCCCAAATAAGTGATCAGCACAGCTGCTTCCAAATAGGAGAA
ACCATAAAATAGGATGAAAATCAAGTAAAATGCAAAGATGTCCACACTGTTTTAAACTTGACCCTGATGAAAATGTGAGCACTGTTAGCA
GATGCCTATGGGAGAGGAAAAGCGTATCTGAAAATGGTCCAGGACAGGAGGATGAAATGAGATCCCAGAGTCCTCACACCTGAATGAATT
ATACATGTGCCTTACCAGGTGAGTGGTCTTTCGAAGATAAAAAACTCTAGTCCCTTTAAACGTTTGCCCCTGGCGTTTCCTAAGTACGAA
AAGGTTTTTAAGTCTTCGAACAGTCTCCTTTCATGACTTTAACAGGATTCTGCCCCCTGAGGTGTAATTTTTTTGTTCTATTTTTTTCCA
CGTACTCCACAGCCAACATCACGAGGTGTAATTTTTAATTTGATCAGAACTGTTACCAAAAAACAACTGTCAGTTTTATTGAGATGGGAA
AAATGTAAACCTATTTTTATTACTTAAGACTTTATGGGAGAGATTAGACACTGGAGGTTTTTAACAGAACGTGTATTTATTAATGTTCAA
AACACTGGAATTACAAATGAGAAGAGTCTACAATAAATTAAGATTTTTGAATTTGTACTTCTGCGGTGCTGGTTTTTCTCCACAAACACC
CCCGCCCCTCCCCATGCCCAGGGTGGCCGTGGAAGGGACGGTTTACGGACGTGCAGCTGAGCTGTCCGTGTCCCATGCTCCCTCAGCCAG
TGGAACGTGCCGGAACTTTTTGTCCATTCCCTAGTAGGCCTGCCACAGCCTAGATGGGCAGTTTTTGTCTTTCACCAAATTTGAGGACTT
TTTTTTTTTGCCATTATTTCTTCAGTTTTCTTTTCTTGCACTGATCTTTCTCCTCTCCTTCTGTGACTCCAGTGACTCAGACGTTAGACC
TCTTGATGTTTTCCCACTGGTCCCTGAGGCTCTGTTCGCATCTTGAAAAATAAAGTCACCTACCCGCCGCCGCTGACGCTGACGGAGCAG
ACGCTGAAGGGCCGGCTCCGGGAGAAGCTGGCCGACTGTGAGCAGAGCCCCACATCCTCGCGCACGTCTTCCCTGGGCTCTGGCGGCCCC
GACTGCGCCATCACAGTCAAGAGCCCTGGGAGGGAGCCGGGGCGTGACCACCTCAACGGGGTGGCCATGAATGTGCGCACTGGGAGCGCC
CAGGCCGATGGCTCCGACTCTGAGGGACGCTGTGGCCAACCACGTTCCGGCCGGCTGGCCCGACCAGAGCCTGGCTGAGAGTGACAGTGA
GGACCCCAGCGGCAAGCCCCGCCTGAAGGTGGAGACCAAGGTCAGCGTGGAGCTGCACCGCGAGGAGCAGGGCAGTCACCGTGGAGAGTA
CCCCCCGGACCAGGAGAGCGGGGGCGCAGCCAGGCTTGCTAGCAGCCAGCCCCCAGAGCAGAGGAAAGGCCACGATTCCGACTCAGATAG
CGAGCTGTCCCTGGATGAGCAGAGCAGCTCTTACGCCTCCTCACACTCGTCAGACAGCGAGGACGATGGGGTGGGAGCTGAGGAAAAATG
GGACCCGGCCAGGGGCGCCGTCCACAGCACCCCCAAAGGGATGAAGGGATCCAGAAGCTCGGCGTGTCCTCTGGGCTGGTGAGGGGCAGC
CACGGAGAGCCAGACGCGTCCCTCATGCCCAGGAGCTGCAAGGATCCCCCTGCGCTCCCTCAACTGCAACACCACCTTCGGTGACGGGCC
TGACATGCTGCGCACAGACTTGGGCGAGTCCACCGCCTCGCTGGACAGCATCGTCAGGGCCCCTTCGTCCTCCTTTTCCACTGCGTGCTC
AACCAGGAGGTCCGGAAGCACCTGAAGGGCGTGCTCGGCGGGAGGAAGCTGCACCTGGAGGACTCCGCCACCACCAGGGCCACCCTGCTG
ACGCTCCCTGCTGAGGACCGCATTCCTCCTGCTGCTGCTCATCAGCGCCACCTGGCTGCTGGGGCTGCTGGCTGTGAACCGCGATGCACT
GAGCTTTCACTACCTCTTCGCCATCTTCAGCGGCTTACAGATCAACACAGTCACTTCTGTCCTATCTGCAAAGGTTTCCTGCCAAAGAAA
GCACCATTATTATGGGAAAAAAGGGATCGTGACTGGCGGTCGGCCTGGACCCCCAGGGCTACGGGAACCCCGACTTCTGCTGGCTGTCGC
TTCAAGACACCCTGATTTGGAGCTTTGCGGGGCCCATCGGAGCTGTTATAATCTTTCTGTGCACAGTGGTTGCCATCCTCCTCCACTACA
TCTACATGAGCACCTTTGCCTGGACCCTCGTGGAGAGCCTGCATGTCTACCGCATGCTGACCGAGGTGCGCAACATCGACACGGGGCCCA
TGCGGTTCTACTACGTCGTGGGCTGGGGCATCCCGGCCATTGTCACAGAACGGGGAGGTCCTGCCTCTGAAGATTGTCACCTATGCCGCT
GTGTCCTTGTCACTGGCAGCCCTGCTGGTGGCCTTCGTCCTCCTGAGCCTGGTCCGCATGCTGCGCTCCAACCTGCACAGCATTCACAAG
CACCTCGCCGTGGCGCTCTTCCTCTCTCAGCTGGTGTTCGTGATTGGGATCAACCAGACGGAAAACCCGCGTTGGTGGGACGGGAGGGTG
GTCTGCCCGGGGCTGCGAGCTCCTGTCCAGGAACCGGACACATGTCGCCTGCCAGTGCAGCCACACAGCCAGCTTTGCGGTGCTCATGGA
TATCTCCAGGCGTGAGGTTGCCTCACCGGCCCATCATTAATACCCCGATGGTGAGCACGCTGGTGTACAGCGAGGGGGCTCCGCTCCCGA
GACCCCTGGAGAGGCCCGTCCTGGTGGAGTTCGCCCTGCTGGAGGTGGAGGAGCGAACCAAGCCTGTCTGCGTGTTCTGGAACCACTCCC
TGGCAAGGCCCCCTGCTGAGGCCGGCTGGCCGGAGGACCACCCCGCAGACCACGCGCCCGGGGCCTGGCACCGAGAGGGAGGCCCCGATC
AGCAGGCGGAGGCGACACCCTGATGACGCTGGCCAGTTCGCCGTCGCTCTGGTCATCATTTACCGCACCCTGGGGCAGCTCCTGCCCGAG
CGCTACGACCCCGACCGTCGCAGCCTCCGTTCTTGCTGTCGACATCTTTGACAAGTTCAACTTTACGGGAGCCAGGGTCCCGCGATTCGA
CACCATCCATGAAGAGTTCCCCAGGGAGCTGGAGTCCTCCGTCTCCTTCCCAGCCGACTTCTTCAGACCACCTGAAGAAAAAGGACGTCA
TCCACTCGGGCAGCGCCCTCCTGGCCCCAGCCACCAGGGCGGCGTGGGAGCAGATCCAGCGGAGCGAGGGCGGCACGGCACAGCTGCTCC
GGCGCCTCGAGGGCTACTTCAGCAACGTGGCACGCAACGTGCGGCGGACGTACCTGCGGCCCTTCGTCATCGTCACCGCCAACATGAAAT
GAGAAGCTGAGCCGCAATGAGACGCAGGTGGACGGCGCCAGGGCCCTGCAGCTGGTGAGGGCGCTGCGCAGTGCTACACAGCACACGGGC
ACGCTCTTTGGCAATGACGTGCGCACGGCCTACCAGCTGCTGGGCCACGTCCTTCAGCACGAGAGCTGGCAGCAGGGCTTCGACCTGGCA
GCCACGCAGGACGCCGACTTTCACGAGGAAATGCGGTCCGACACTGCAGCGGGGAGAAGGGCTGGCTGCCCCCAGAGCTCTTTAACTGTA
CCACCATCTCCTTCGTGGACCTCAGGGCCATGTGATCTACAATGGCTGTCCCAAAGCATTTGAGGCCGGCATCTGGTGGCCACAGACCAA
GTTCGGGCAGCCGGCTGCGGTGCCATGCCCTAAGGGATCCGTTGGAGAATTACTACAAGCTCCTAGCCCAGGACACCTGTCTGCCCTGCG
ACTGCTTCCCCCATGGCTCCCACAGCCGCACTTGCGACATGGCCACCGGGCAGTGTGCCTGCAAGCCCGGCGTCATCGGCCGCCAGTGCA
ACCGCTGCGACAACCCGTTTGCCGAGGTCACCACGCTCGGCTGTGAAGACTCGACCTTCCGTGCCCCAGAGGCTGGTGGGGGAACCCCGT
CTGTGGACCCTGCCACTGTGCCGTCAGCAAAGGCTTTGATCCCGACTGTAATAAGACCAACGGCCAGTGCCAATGCAAGCTGTGTGGATG
CCTGTCACCTGAACCCCTGCGAGAACATGGGGGCCTGCGTGCGCTCCCCCGGCTCCCCGCAGGGCTACGTGTGCGAGTGTGGGCCCAGTC

>22311_22311_3_DEPDC5-CELSR1_DEPDC5_chr22_32275603_ENST00000382112_CELSR1_chr22_46792627_ENST00000262738_length(amino acids)=1331AA_BP=1297
MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKEDLQKETISVDQTVTQVFRLRPYQDVYVNVV
DPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRASIRQDHKGRFYEDFYKVVVQNERREEWTSL
LVTIKKLFIQYPVLVRLEQAEGFPQGDNSTSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFTPRIKLAGKKPASEKAKNGRDTSLGSPKESE
NALPIQVDYDAYDAQVFRLPGPSRAQCLTTCRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAI
QIHHQTRQNMAELQGSGQRDPTHSSAELLELAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
PDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDEDGVQMTAQQVFEEFICQRLMQGYQIIVQPKT
QKPNPAVPPPLSSSPLYSRGLVSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFS
HERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIYGDRPRADEDEWQLLDGFVRFVEGLNRIRRR
HRSDRMMRKGTAMKGLQMTGPISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRKD
GAFFMEFVRSPRTASSAFYPQVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSSSQQLVASSLTSSSTLTE
ILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRA

--------------------------------------------------------------
>22311_22311_4_DEPDC5-CELSR1_DEPDC5_chr22_32275603_ENST00000400246_CELSR1_chr22_46792627_ENST00000262738_length(transcript)=9754nt_BP=4082nt
ATCTGGAGGAGGCGCAGGGAACCTGGAGAGGGTCCAGCCCTCAGTGCCCCGGCCAGAGGCGGGAAGGGGCTCTAGAGCTTCGGGAGGCAA
GATGACTTCTCTGCCCCAAGCTTGGAACAGCTAAAGGGAAAAACAGTGCAAGATGAGAACAACAAAGGTCTACAAACTCGTCATCCACAA
GAAGGGCTTTGGGGGCAGTGATGATGAGCTAGTTGTGAACCCCAAAGTGTTCCCTCACATCAAGCTTGGAGACATTGTAGAGATTGCACA
CCCCAACGATGAATACAGCCCTCTGCTTTTGCAGGTCAAGTCTCTTAAGGAAGATTTACAGAAGGAAACTATCAGTGTGGACCAGACTGT
GACTCAAGTGTTCCGGCTGAGACCTTATCAGGATGTCTATGTTAATGTCGTAGACCCTAAGGATGTGACCCTTGACCTAGTGGAATTAAC
TTTTAAGGATCAGTATATTGGCCGTGGGGATATGTGGCGACTAAAGAAAAGTTTGGTCAGCACATGTGCCTATATCACCCAGAAGGTGGA
GTTTGCTGGCATCAGAGCACAGGCTGGTGAACTGTGGGTTAAGAATGAGAAGGTCATGTGTGGCTACATCAGTGAAGATACCAGGGTGGT
GTTTCGTTCTACGTCGGCTATGGTTTACATATTTATTCAGATGAGCTGTGAAATGTGGGATTTTGATATTTATGGGGATTTGTATTTTGA
GAAAGCTGTGAATGGTTTCCTTGCTGATCTATTTACCAAGTGGAAGGAGAAGAACTGTAGTCATGAAGTGACAGTGGTCCTGTTTTCTAG
AACTTTCTATGATGCAAAATCTGTTGATGAATTTCCTGAAATAAACCGAGCCTCAATTCGACAGGATCACAAGGGGAGATTCTATGAAGA
CTTTTACAAAGTGGTGGTGCAGAATGAGAGAAGAGAAGAATGGACTTCACTTCTCGTAACCATTAAAAAACTCTTCATCCAGTATCCAGT
GTTGGTGCGACTGGAACAGGCAGAGGGCTTTCCTCAAGGAGATAATTCTACCTCAGCACAAGGAAACTACCTGGAGGCCATCAATCTGTC
ATTCAATGTGTTTGATAAGCACTACATCAACCGCAACTTTGACCGAACTGGGCAGATGTCAGTGGTGATCACGCCCGGGGTGGGTGTCTT
TGAAGTGGACCGCCTACTCATGATCCTGACCAAGCAGCGGATGATAGATAATGGAATTGGTGTGGATTTGGTGTGCATGGGAGAGCAACC
GTTACATGCTGTCCCATTGTTCAAGCTCCATAATCGGAGTGCTCCCCGTGATTCTCGTCTGGGCGATGACTATAATATCCCTCACTGGAT
AAACCACAGTTTCTACACATCCAAAAGCCAGCTCTTTTGTAATAGTTTCACCCCACGAATAAAACTGGCAGGAAAGAAGCCCGCCTCTGA
GAAAGCAAAAAATGGCCGTGATACATCTCTCGGGAGTCCAAAAGAATCTGAGAACGCCCTTCCCATCCAAGTAGATTATGACGCCTATGA
CGCTCAAGTGTTCAGGCTGCCCGGCCCATCCCGGGCCCAGTGCCTCACCACCTGCAGATCTGTGCGAGAGCGAGAGAGTCACAGTCGAAA
GAGTGCCAGCTCCTGTGATGTTTCATCCAGCCCTTCCCTACCAAGCCGCACACTGCCCACTGAGGAAGTGAGGAGCCAGGCTTCTGACGA
CAGCTCCCTAGGCAAGAGTGCCAACATCCTGATGATCCCACACCCCCACCTGCACCAGTATGAAGTCAGCAGCTCCTTGGGATACACCAG
CACTCGAGATGTCCTGGAGAACATGATGGAGCCACCACAGCGAGACTCCAGTGCACCAGGGAGGTTTCACGTTGGCAGTGCAGAATCCAT
GCTGCATGTTCGACCTGGTGGATACACGCCCCAGAGAGCACTGATTAACCCCTTCGCTCCCTCTCGGATGCCCATGAAGCTTACGTCCAA
CAGAAGGCGCTGGATGCACACTTTTCCTGTGGGGCCATCCGGAGAAGCCATCCAGATCCACCACCAGACCCGACAGAATATGGCGGAGCT
ACAAGGCAGCGGGCAGAGGGATCCAACTCACTCCTCTGCAGAGCTGCTGGAGTTAGCATATCATGAAGCTGCTGGAAGGCACAGCAATTC
CCGCCAGCCTGGTGACGGCATGTCCTTCTTGAACTTCAGTGGAACAGAGGAGCTTTCTGTCGGCCTGCTTAGCAACAGTGGTGCAGGTAT
GAATCCTAGGACCCAGAATAAGGATTCTCTAGAGGACAGTGTTTCTACCTCTCCAGACCCAATTCTGACACTGTCTGCTCCCCCTGTAGT
GCCAGGCTTCTGTTGCACAGTTGGAGTGGACTGGAAGTCTCTCACTACTCCGGCGTGCCTCCCCCTTACCACCGACTACTTCCCTGACCG
CCAGGGCCTGCAGAATGACTACACAGAGGGCTGTTATGATCTCCTTCCAGAAGCAGACATCGACAGGAGGGACGAAGATGGTGTGCAGAT
GACAGCCCAGCAGGTATTTGAAGAGTTTATTTGCCAACGTCTCATGCAGGGCTACCAAATCATAGTGCAGCCCAAGACACAGAAACCCAA
TCCTGCTGTCCCGCCCCCGCTGAGCAGTAGCCCACTCTATAGCCGAGGCCTTGTGTCCCGAAACCGCCCTGAGGAGGAGGACCAGTATTG
GCTGAGTATGGGCAGAACGTTCCACAAAGTGACGCTGAAGGATAAGATGATCACAGTGACGCGATACCTTCCCAAGTATCCTTATGAATC
TGCCCAGATCCACTACACCTACAGCCTCTGTCCTTCCCACTCAGACTCAGAGTTCGTCTCCTGCTGGGTGGAATTCTCCCACGAACGGCT
GGAGGAGTACAAGTGGAATTACTTAGATCAGTATATCTGTTCTGCCGGCTCTGAAGACTTCAGCTTAATTGAGTCCCTGAAGTTCTGGAG
GACCCGCTTCCTGCTGCTGCCAGCCTGTGTCACCGCCACCAAGCGCATCACGGAGGGGGAGGCCCACTGCGACATCTATGGGGACAGGCC
CCGTGCAGACGAGGACGAGTGGCAACTCCTGGATGGTTTTGTCCGCTTTGTGGAGGGCTTGAATCGCATTCGCAGGCGGCATCGCTCGGA
TCGCATGATGCGGAAAGGGACCGCCATGAAAGGCTTGCAGATGACTGGGCCCATTTCCACGCATTCTCTGGAGTCAACTGCACCCCCAGT
GGGGAAGAAGGGAACCTCAGCTCTCTCTGCCCTGTTGGAGATGGAGGCCAGTCAGAAGTGCCTGGGAGAACAGCAGGCAGCTGTGCATGG
TGGGAAGAGCTCCGCCCAGTCAGCCGAGAGCAGCAGCGTTGCCATGACTCCCACCTACATGGACAGCCCACGAAAGGACGGGGCCTTCTT
TATGGAGTTTGTCCGCAGCCCACGCACAGCATCGTCCGCCTTCTACCCTCAGGTATCTGTGGACCAAACAGCCACTCCTATGTTGGACGG
CACCAGTTTGGGCATATGCACAGGCCAATCCATGGACAGAGGCAACAGCCAGACCTTTGGGAACTCCCAGAACATAGGAGAACAGGGCTA
CTCCTCCACAAACTCCAGTGACAGCAGCTCTCAGCAGCTGGTGGCAAGCTCCTTGACCTCATCCTCTACCCTGACAGAGATCCTGGAAGC
CATGAAGCACCCCTCGACAGGAGTCCAGCTGCTCTCTGAACAGAAGGGCCTCTCACCGTACTGCTTCATCAGCGCGGAGGTGGTACACTG
GTTGGTGAACCACGTGGAGGGGATCCAGACACAGGCGATGGCCATTGACATCATGCAGAAAATGCTGGAAGAGCAGCTCATCACACATGC
ATCTGGCGAAGCCTGGCGGACCTTCATCTACGGCTTCTATTTCTACAAGATAGTAACGGACAAAGAGCCCGACCGAGCAGAAGAGCTCGT
GCACTCTGAGATTCCTGCCTTTCTCCTGCCCTGGCTGCCTAGCCGGCCAGCCTCCTATGCAAGTAGGCACAGCTCCTTTAGCCGAAGTTT
TGGAGGACGGAGCCAGGCGGCAGCACTTTTAGGAAACCGTGAGGCAAGCCCGTCACCCCACACAGGCTGCGGCATCACCCTCAGACCTTG
GAGCCCAAGGGGCCACTGCCCTTGAAGTGGAGTGGGCCCAGAGTGTGGCGGTCCCCATGGTGGCAGCCCCCCGACTGATCATCCAGACAC
AAAGGTCTTGGTTCTCCCAGGAGCTCAGGGCCTGTCAGACCTGGTGACAAGTGCCAAAGGCCACAGGCATGAGGGAGGCGTGGACCACTG
GGCCAGCACCGCTGAGTCCTAAGACTGCAGTCAAAGCCAGAACTGAGAGGGGACCCCAGACTGGGCCCAGAGGCTGGCCAGAGTTCAGGA
ACGCCGGGCACAGACCAAAGACCGCGGTCCAGCCCCGCCCAGGCGGGCATCTCATGGCAGTGCGGACCCGTGGCTGGCAGCCCGGGCAGT
CCTTTGCAAAGGCACCCCTTGTCTTAAAATCACTTCGCTATGTGGGAAAGGTGGAGATACTTTTATATATTTGTATGGGACTCTGAGGAG
GTGCAACCTGTATATATATTGCATTCGTGCTGACTTTGTTATCCCGAGAGATCCATGCAATGATCTCTTGCTGTCTTCTCTGTCAAGATT
GCACAGTTGTACTTGAATCTGGCATGTGTTGACGAAACTGGTGCCCCAGCAGATCAAAGGTGGGAAATACGTCAGCAGTGGGGCTAAAAC
CAAGCGGCTAGAAGCCCTACAGCTGCCTTCGGCCAGGAAGTGAGGATGGTGTGGGCCCTCCCCGCCGGCCCCCTGGGTCCCCAGTGTTCG
CTGTGTGTGCGTTTGTCCTCTGCTGCCATCTGCCCCGGCTGTGTGAATTCAAGACAGGGCAGTGCAGCACTAGGCAGGTGTGAGGAGCCC
TGCTGAGGTCACTGTGGGGCACGGTTGCCACACGGCTGTCATTTTTCACCTGGTCATTCTGTGACCACCACCCCCTCCCCTCACCGCCTC
CCAGGTGGCCCGGGAGCTGCAGGTGGGGATGGCTTTGTCCTTTGCTCCTGCTCCCCGTGGGACCTGGGACCTTAAAGCGTTGCAGGTTCC
TGATTTGGACAGAGGTGTGGGGCCTTCCAGGCCGTTACATACCTCCTGCCAATTCTCTAACTCTCTGAGACTGCGAGGATCTCCAGGCAG
GGTTCTCCCCTCTGGAGTCTGACCAATTACTTCATTTTGCTTCAAATGGCCAATTGTGCAGAGGGACAAAGCCACAGCCACACTCTTCAA
CGGTTACCAAACTGTTTTTGGAAATTCACACCAAGGTCGGGCCCACTGCAGGCAGCTGGCACAGCGTGGCCCGAGGGGCTGTGGAACGGG
TCCCGGAACTGTCAGACATGTTTGATTTTAGCGTTTCCTTTGTTCTTCAAATCAGGTGCCCAAATAAGTGATCAGCACAGCTGCTTCCAA
ATAGGAGAAACCATAAAATAGGATGAAAATCAAGTAAAATGCAAAGATGTCCACACTGTTTTAAACTTGACCCTGATGAAAATGTGAGCA
CTGTTAGCAGATGCCTATGGGAGAGGAAAAGCGTATCTGAAAATGGTCCAGGACAGGAGGATGAAATGAGATCCCAGAGTCCTCACACCT
GAATGAATTATACATGTGCCTTACCAGGTGAGTGGTCTTTCGAAGATAAAAAACTCTAGTCCCTTTAAACGTTTGCCCCTGGCGTTTCCT
AAGTACGAAAAGGTTTTTAAGTCTTCGAACAGTCTCCTTTCATGACTTTAACAGGATTCTGCCCCCTGAGGTGTAATTTTTTTGTTCTAT
TTTTTTCCACGTACTCCACAGCCAACATCACGAGGTGTAATTTTTAATTTGATCAGAACTGTTACCAAAAAACAACTGTCAGTTTTATTG
AGATGGGAAAAATGTAAACCTATTTTTATTACTTAAGACTTTATGGGAGAGATTAGACACTGGAGGTTTTTAACAGAACGTGTATTTATT
AATGTTCAAAACACTGGAATTACAAATGAGAAGAGTCTACAATAAATTAAGATTTTTGAATTTGTACTTCTGCGGTGCTGGTTTTTCTCC
ACAAACACCCCCGCCCCTCCCCATGCCCAGGGTGGCCGTGGAAGGGACGGTTTACGGACGTGCAGCTGAGCTGTCCGTGTCCCATGCTCC
CTCAGCCAGTGGAACGTGCCGGAACTTTTTGTCCATTCCCTAGTAGGCCTGCCACAGCCTAGATGGGCAGTTTTTGTCTTTCACCAAATT
TGAGGACTTTTTTTTTTTGCCATTATTTCTTCAGTTTTCTTTTCTTGCACTGATCTTTCTCCTCTCCTTCTGTGACTCCAGTGACTCAGA
CGTTAGACCTCTTGATGTTTTCCCACTGGTCCCTGAGGCTCTGTTCGCATCTTGAAAAATAAAGTCACCTACCCGCCGCCGCTGACGCTG
ACGGAGCAGACGCTGAAGGGCCGGCTCCGGGAGAAGCTGGCCGACTGTGAGCAGAGCCCCACATCCTCGCGCACGTCTTCCCTGGGCTCT
GGCGGCCCCGACTGCGCCATCACAGTCAAGAGCCCTGGGAGGGAGCCGGGGCGTGACCACCTCAACGGGGTGGCCATGAATGTGCGCACT
GGGAGCGCCCAGGCCGATGGCTCCGACTCTGAGGGACGCTGTGGCCAACCACGTTCCGGCCGGCTGGCCCGACCAGAGCCTGGCTGAGAG
TGACAGTGAGGACCCCAGCGGCAAGCCCCGCCTGAAGGTGGAGACCAAGGTCAGCGTGGAGCTGCACCGCGAGGAGCAGGGCAGTCACCG
TGGAGAGTACCCCCCGGACCAGGAGAGCGGGGGCGCAGCCAGGCTTGCTAGCAGCCAGCCCCCAGAGCAGAGGAAAGGCCACGATTCCGA
CTCAGATAGCGAGCTGTCCCTGGATGAGCAGAGCAGCTCTTACGCCTCCTCACACTCGTCAGACAGCGAGGACGATGGGGTGGGAGCTGA
GGAAAAATGGGACCCGGCCAGGGGCGCCGTCCACAGCACCCCCAAAGGGATGAAGGGATCCAGAAGCTCGGCGTGTCCTCTGGGCTGGTG
AGGGGCAGCCACGGAGAGCCAGACGCGTCCCTCATGCCCAGGAGCTGCAAGGATCCCCCTGCGCTCCCTCAACTGCAACACCACCTTCGG
TGACGGGCCTGACATGCTGCGCACAGACTTGGGCGAGTCCACCGCCTCGCTGGACAGCATCGTCAGGGCCCCTTCGTCCTCCTTTTCCAC
TGCGTGCTCAACCAGGAGGTCCGGAAGCACCTGAAGGGCGTGCTCGGCGGGAGGAAGCTGCACCTGGAGGACTCCGCCACCACCAGGGCC
ACCCTGCTGACGCTCCCTGCTGAGGACCGCATTCCTCCTGCTGCTGCTCATCAGCGCCACCTGGCTGCTGGGGCTGCTGGCTGTGAACCG
CGATGCACTGAGCTTTCACTACCTCTTCGCCATCTTCAGCGGCTTACAGATCAACACAGTCACTTCTGTCCTATCTGCAAAGGTTTCCTG
CCAAAGAAAGCACCATTATTATGGGAAAAAAGGGATCGTGACTGGCGGTCGGCCTGGACCCCCAGGGCTACGGGAACCCCGACTTCTGCT
GGCTGTCGCTTCAAGACACCCTGATTTGGAGCTTTGCGGGGCCCATCGGAGCTGTTATAATCTTTCTGTGCACAGTGGTTGCCATCCTCC
TCCACTACATCTACATGAGCACCTTTGCCTGGACCCTCGTGGAGAGCCTGCATGTCTACCGCATGCTGACCGAGGTGCGCAACATCGACA
CGGGGCCCATGCGGTTCTACTACGTCGTGGGCTGGGGCATCCCGGCCATTGTCACAGAACGGGGAGGTCCTGCCTCTGAAGATTGTCACC
TATGCCGCTGTGTCCTTGTCACTGGCAGCCCTGCTGGTGGCCTTCGTCCTCCTGAGCCTGGTCCGCATGCTGCGCTCCAACCTGCACAGC
ATTCACAAGCACCTCGCCGTGGCGCTCTTCCTCTCTCAGCTGGTGTTCGTGATTGGGATCAACCAGACGGAAAACCCGCGTTGGTGGGAC
GGGAGGGTGGTCTGCCCGGGGCTGCGAGCTCCTGTCCAGGAACCGGACACATGTCGCCTGCCAGTGCAGCCACACAGCCAGCTTTGCGGT
GCTCATGGATATCTCCAGGCGTGAGGTTGCCTCACCGGCCCATCATTAATACCCCGATGGTGAGCACGCTGGTGTACAGCGAGGGGGCTC
CGCTCCCGAGACCCCTGGAGAGGCCCGTCCTGGTGGAGTTCGCCCTGCTGGAGGTGGAGGAGCGAACCAAGCCTGTCTGCGTGTTCTGGA
ACCACTCCCTGGCAAGGCCCCCTGCTGAGGCCGGCTGGCCGGAGGACCACCCCGCAGACCACGCGCCCGGGGCCTGGCACCGAGAGGGAG
GCCCCGATCAGCAGGCGGAGGCGACACCCTGATGACGCTGGCCAGTTCGCCGTCGCTCTGGTCATCATTTACCGCACCCTGGGGCAGCTC
CTGCCCGAGCGCTACGACCCCGACCGTCGCAGCCTCCGTTCTTGCTGTCGACATCTTTGACAAGTTCAACTTTACGGGAGCCAGGGTCCC
GCGATTCGACACCATCCATGAAGAGTTCCCCAGGGAGCTGGAGTCCTCCGTCTCCTTCCCAGCCGACTTCTTCAGACCACCTGAAGAAAA
AGGACGTCATCCACTCGGGCAGCGCCCTCCTGGCCCCAGCCACCAGGGCGGCGTGGGAGCAGATCCAGCGGAGCGAGGGCGGCACGGCAC
AGCTGCTCCGGCGCCTCGAGGGCTACTTCAGCAACGTGGCACGCAACGTGCGGCGGACGTACCTGCGGCCCTTCGTCATCGTCACCGCCA
ACATGAAATGAGAAGCTGAGCCGCAATGAGACGCAGGTGGACGGCGCCAGGGCCCTGCAGCTGGTGAGGGCGCTGCGCAGTGCTACACAG
CACACGGGCACGCTCTTTGGCAATGACGTGCGCACGGCCTACCAGCTGCTGGGCCACGTCCTTCAGCACGAGAGCTGGCAGCAGGGCTTC
GACCTGGCAGCCACGCAGGACGCCGACTTTCACGAGGAAATGCGGTCCGACACTGCAGCGGGGAGAAGGGCTGGCTGCCCCCAGAGCTCT
TTAACTGTACCACCATCTCCTTCGTGGACCTCAGGGCCATGTGATCTACAATGGCTGTCCCAAAGCATTTGAGGCCGGCATCTGGTGGCC
ACAGACCAAGTTCGGGCAGCCGGCTGCGGTGCCATGCCCTAAGGGATCCGTTGGAGAATTACTACAAGCTCCTAGCCCAGGACACCTGTC
TGCCCTGCGACTGCTTCCCCCATGGCTCCCACAGCCGCACTTGCGACATGGCCACCGGGCAGTGTGCCTGCAAGCCCGGCGTCATCGGCC
GCCAGTGCAACCGCTGCGACAACCCGTTTGCCGAGGTCACCACGCTCGGCTGTGAAGACTCGACCTTCCGTGCCCCAGAGGCTGGTGGGG
GAACCCCGTCTGTGGACCCTGCCACTGTGCCGTCAGCAAAGGCTTTGATCCCGACTGTAATAAGACCAACGGCCAGTGCCAATGCAAGCT
GTGTGGATGCCTGTCACCTGAACCCCTGCGAGAACATGGGGGCCTGCGTGCGCTCCCCCGGCTCCCCGCAGGGCTACGTGTGCGAGTGTG

>22311_22311_4_DEPDC5-CELSR1_DEPDC5_chr22_32275603_ENST00000400246_CELSR1_chr22_46792627_ENST00000262738_length(amino acids)=1340AA_BP=1306
MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKEDLQKETISVDQTVTQVFRLRPYQDVYVNVV
DPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRASIRQDHKGRFYEDFYKVVVQNERREEWTSL
LVTIKKLFIQYPVLVRLEQAEGFPQGDNSTSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFTPRIKLAGKKPASEKAKNGRDTSLGSPKESE
NALPIQVDYDAYDAQVFRLPGPSRAQCLTTCRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAI
QIHHQTRQNMAELQGSGQRDPTHSSAELLELAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
PDPILTLSAPPVVPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDEDGVQMTAQQVFEEFICQRLMQG
YQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSE
FVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIYGDRPRADEDEWQLLDGFVRFV
EGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTP
TYMDSPRKDGAFFMEFVRSPRTASSAFYPQVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSSSQQLVASS
LTSSSTLTEILEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKI

--------------------------------------------------------------
>22311_22311_5_DEPDC5-CELSR1_DEPDC5_chr22_32275603_ENST00000400248_CELSR1_chr22_46792627_ENST00000262738_length(transcript)=9578nt_BP=3906nt
GAGGCAAGATGACTTCTCTGCCCCAAGCTTGGAACAGCTAAAGGGAAAAACAGTGCAAGATGAGAACAACAAAGGTCTACAAACTCGTCA
TCCACAAGAAGGGCTTTGGGGGCAGTGATGATGAGCTAGTTGTGAACCCCAAAGTGTTCCCTCACATCAAGCTTGGAGACATTGTAGAGA
TTGCACACCCCAACGATGAATACAGCCCTCTGCTTTTGCAGGTCAAGTCTCTTAAGGAAGATTTACAGAAGGAAACTATCAGTGTGGACC
AGACTGTGACTCAAGTGTTCCGGCTGAGACCTTATCAGGATGTCTATGTTAATGTCGTAGACCCTAAGGATGTGACCCTTGACCTAGTGG
AATTAACTTTTAAGGATCAGTATATTGGCCGTGGGGATATGTGGCGACTAAAGAAAAGTTTGGTCAGCACATGTGCCTATATCACCCAGA
AGGTGGAGTTTGCTGGCATCAGAGCACAGGCTGGTGAACTGTGGGTTAAGAATGAGAAGGTCATGTGTGGCTACATCAGTGAAGATACCA
GGGTGGTGTTTCGTTCTACGTCGGCTATGGTTTACATATTTATTCAGATGAGCTGTGAAATGTGGGATTTTGATATTTATGGGGATTTGT
ATTTTGAGAAAGCTGTGAATGGTTTCCTTGCTGATCTATTTACCAAGTGGAAGGAGAAGAACTGTAGTCATGAAGTGACAGTGGTCCTGT
TTTCTAGAACTTTCTATGATGCAAAATCTGTTGATGAATTTCCTGAAATAAACCGAGCCTCAATTCGACAGGATCACAAGGGGAGATTCT
ATGAAGACTTTTACAAAGTGGTGGTGCAGAATGAGAGAAGAGAAGAATGGACTTCACTTCTCGTAACCATTAAAAAACTCTTCATCCAGT
ATCCAGTGTTGGTGCGACTGGAACAGGCAGAGGGCTTTCCTCAAGGAGATAATTCTACCTCAGCACAAGGAAACTACCTGGAGGCCATCA
ATCTGTCATTCAATGTGTTTGATAAGCACTACATCAACCGCAACTTTGACCGAACTGGGCAGATGTCAGTGGTGATCACGCCCGGGGTGG
GTGTCTTTGAAGTGGACCGCCTACTCATGATCCTGACCAAGCAGCGGATGATAGATAATGGAATTGGTGTGGATTTGGTGTGCATGGGAG
AGCAACCGTTACATGCTGTCCCATTGTTCAAGCTCCATAATCGGAGTGCTCCCCGTGATTCTCGTCTGGGCGATGACTATAATATCCCTC
ACTGGATAAACCACAGTTTCTACACATCCAAAAGCCAGCTCTTTTGTAATAGTTTCACCCCACGAATAAAACTGGCAGGAAAGAAGCCCG
CCTCTGAGAAAGCAAAAAATGGCCGTGATACATCTCTCGGGAGTCCAAAAGAATCTGAGAACGCCCTTCCCATCCAAGTAGATTATGACG
CCTATGACGCTCAAGTGTTCAGGCTGCCCGGCCCATCCCGGGCCCAGTGCCTCACCACCTGCAGATCTGTGCGAGAGCGAGAGAGTCACA
GTCGAAAGAGTGCCAGCTCCTGTGATGTTTCATCCAGCCCTTCCCTACCAAGCCGCACACTGCCCACTGAGGAAGTGAGGAGCCAGGCTT
CTGACGACAGCTCCCTAGGCAAGAGTGCCAACATCCTGATGATCCCACACCCCCACCTGCACCAGTATGAAGTCAGCAGCTCCTTGGGAT
ACACCAGCACTCGAGATGTCCTGGAGAACATGATGGAGCCACCACAGCGAGACTCCAGTGCACCAGGGAGGTTTCACGTTGGCAGTGCAG
AATCCATGCTGCATGTTCGACCTGGTGGATACACGCCCCAGAGAGCACTGATTAACCCCTTCGCTCCCTCTCGGATGCCCATGAAGCTTA
CGTCCAACAGAAGGCGCTGGATGCACACTTTTCCTGTGGGGCCATCCGGAGAAGCCATCCAGATCCACCACCAGACCCGACAGAATATGG
CGGAGCTACAAGGCAGCGGGCAGAGGGATCCAACTCACTCCTCTGCAGAGCTGCTGGAGTTAGCATATCATGAAGCTGCTGGAAGGCACA
GCAATTCCCGCCAGCCTGGTGACGGCATGTCCTTCTTGAACTTCAGTGGAACAGAGGAGCTTTCTGTCGGCCTGCTTAGCAACAGTGGTG
CAGGTATGAATCCTAGGACCCAGAATAAGGATTCTCTAGAGGACAGTGTTTCTACCTCTCCAGACCCAATGCCAGGCTTCTGTTGCACAG
TTGGAGTGGACTGGAAGTCTCTCACTACTCCGGCGTGCCTCCCCCTTACCACCGACTACTTCCCTGACCGCCAGGGCCTGCAGAATGACT
ACACAGAGGGCTGTTATGATCTCCTTCCAGAAGCAGACATCGACAGGAGGGACGAAGATGGTGTGCAGATGACAGCCCAGCAGGTATTTG
AAGAGTTTATTTGCCAACGTCTCATGCAGGGCTACCAAATCATAGTGCAGCCCAAGACACAGAAACCCAATCCTGCTGTCCCGCCCCCGC
TGAGCAGTAGCCCACTCTATAGCCGAGGCCTTGTGTCCCGAAACCGCCCTGAGGAGGAGGACCAGTATTGGCTGAGTATGGGCAGAACGT
TCCACAAAGTGACGCTGAAGGATAAGATGATCACAGTGACGCGATACCTTCCCAAGTATCCTTATGAATCTGCCCAGATCCACTACACCT
ACAGCCTCTGTCCTTCCCACTCAGACTCAGAGTTCGTCTCCTGCTGGGTGGAATTCTCCCACGAACGGCTGGAGGAGTACAAGTGGAATT
ACTTAGATCAGTATATCTGTTCTGCCGGCTCTGAAGACTTCAGCTTAATTGAGTCCCTGAAGTTCTGGAGGACCCGCTTCCTGCTGCTGC
CAGCCTGTGTCACCGCCACCAAGCGCATCACGGAGGGGGAGGCCCACTGCGACATCTATGGGGACAGGCCCCGTGCAGACGAGGACGAGT
GGCAACTCCTGGATGGTTTTGTCCGCTTTGTGGAGGGCTTGAATCGCATTCGCAGGCGGCATCGCTCGGATCGCATGATGCGGAAAGGGA
CCGCCATGAAAGGCTTGCAGATGACTGGGCCCATTTCCACGCATTCTCTGGAGTCAACTGCACCCCCAGTGGGGAAGAAGGGAACCTCAG
CTCTCTCTGCCCTGTTGGAGATGGAGGCCAGTCAGAAGTGCCTGGGAGAACAGCAGGCAGCTGTGCATGGTGGGAAGAGCTCCGCCCAGT
CAGCCGAGAGCAGCAGCGTTGCCATGACTCCCACCTACATGGACAGCCCACGAAAGGTATCTGTGGACCAAACAGCCACTCCTATGTTGG
ACGGCACCAGTTTGGGCATATGCACAGGCCAATCCATGGACAGAGGCAACAGCCAGACCTTTGGGAACTCCCAGAACATAGGAGAACAGG
GCTACTCCTCCACAAACTCCAGTGACAGCAGCTCTCAGCAGCTGGTGGCAAGCTCCTTGACCTCATCCTCTACCCTGACAGAGATCCTGG
AAGCCATGAAGCACCCCTCGACAGGAGTCCAGCTGCTCTCTGAACAGAAGGGCCTCTCACCGTACTGCTTCATCAGCGCGGAGGTGGTAC
ACTGGTTGGTGAACCACGTGGAGGGGATCCAGACACAGGCGATGGCCATTGACATCATGCAGAAAATGCTGGAAGAGCAGCTCATCACAC
ATGCATCTGGCGAAGCCTGGCGGACCTTCATCTACGGCTTCTATTTCTACAAGATAGTAACGGACAAAGAGCCCGACCGAGCAGAAGAGC
TCGTGCACTCTGAGATTCCTGCCTTTCTCCTGCCCTGGCTGCCTAGCCGGCCAGCCTCCTATGCAAGTAGGCACAGCTCCTTTAGCCGAA
GTTTTGGAGGACGGAGCCAGGCGGCAGCACTTTTAGGAAACCGTGAGGCAAGCCCGTCACCCCACACAGGCTGCGGCATCACCCTCAGAC
CTTGGAGCCCAAGGGGCCACTGCCCTTGAAGTGGAGTGGGCCCAGAGTGTGGCGGTCCCCATGGTGGCAGCCCCCCGACTGATCATCCAG
ACACAAAGGTCTTGGTTCTCCCAGGAGCTCAGGGCCTGTCAGACCTGGTGACAAGTGCCAAAGGCCACAGGCATGAGGGAGGCGTGGACC
ACTGGGCCAGCACCGCTGAGTCCTAAGACTGCAGTCAAAGCCAGAACTGAGAGGGGACCCCAGACTGGGCCCAGAGGCTGGCCAGAGTTC
AGGAACGCCGGGCACAGACCAAAGACCGCGGTCCAGCCCCGCCCAGGCGGGCATCTCATGGCAGTGCGGACCCGTGGCTGGCAGCCCGGG
CAGTCCTTTGCAAAGGCACCCCTTGTCTTAAAATCACTTCGCTATGTGGGAAAGGTGGAGATACTTTTATATATTTGTATGGGACTCTGA
GGAGGTGCAACCTGTATATATATTGCATTCGTGCTGACTTTGTTATCCCGAGAGATCCATGCAATGATCTCTTGCTGTCTTCTCTGTCAA
GATTGCACAGTTGTACTTGAATCTGGCATGTGTTGACGAAACTGGTGCCCCAGCAGATCAAAGGTGGGAAATACGTCAGCAGTGGGGCTA
AAACCAAGCGGCTAGAAGCCCTACAGCTGCCTTCGGCCAGGAAGTGAGGATGGTGTGGGCCCTCCCCGCCGGCCCCCTGGGTCCCCAGTG
TTCGCTGTGTGTGCGTTTGTCCTCTGCTGCCATCTGCCCCGGCTGTGTGAATTCAAGACAGGGCAGTGCAGCACTAGGCAGGTGTGAGGA
GCCCTGCTGAGGTCACTGTGGGGCACGGTTGCCACACGGCTGTCATTTTTCACCTGGTCATTCTGTGACCACCACCCCCTCCCCTCACCG
CCTCCCAGGTGGCCCGGGAGCTGCAGGTGGGGATGGCTTTGTCCTTTGCTCCTGCTCCCCGTGGGACCTGGGACCTTAAAGCGTTGCAGG
TTCCTGATTTGGACAGAGGTGTGGGGCCTTCCAGGCCGTTACATACCTCCTGCCAATTCTCTAACTCTCTGAGACTGCGAGGATCTCCAG
GCAGGGTTCTCCCCTCTGGAGTCTGACCAATTACTTCATTTTGCTTCAAATGGCCAATTGTGCAGAGGGACAAAGCCACAGCCACACTCT
TCAACGGTTACCAAACTGTTTTTGGAAATTCACACCAAGGTCGGGCCCACTGCAGGCAGCTGGCACAGCGTGGCCCGAGGGGCTGTGGAA
CGGGTCCCGGAACTGTCAGACATGTTTGATTTTAGCGTTTCCTTTGTTCTTCAAATCAGGTGCCCAAATAAGTGATCAGCACAGCTGCTT
CCAAATAGGAGAAACCATAAAATAGGATGAAAATCAAGTAAAATGCAAAGATGTCCACACTGTTTTAAACTTGACCCTGATGAAAATGTG
AGCACTGTTAGCAGATGCCTATGGGAGAGGAAAAGCGTATCTGAAAATGGTCCAGGACAGGAGGATGAAATGAGATCCCAGAGTCCTCAC
ACCTGAATGAATTATACATGTGCCTTACCAGGTGAGTGGTCTTTCGAAGATAAAAAACTCTAGTCCCTTTAAACGTTTGCCCCTGGCGTT
TCCTAAGTACGAAAAGGTTTTTAAGTCTTCGAACAGTCTCCTTTCATGACTTTAACAGGATTCTGCCCCCTGAGGTGTAATTTTTTTGTT
CTATTTTTTTCCACGTACTCCACAGCCAACATCACGAGGTGTAATTTTTAATTTGATCAGAACTGTTACCAAAAAACAACTGTCAGTTTT
ATTGAGATGGGAAAAATGTAAACCTATTTTTATTACTTAAGACTTTATGGGAGAGATTAGACACTGGAGGTTTTTAACAGAACGTGTATT
TATTAATGTTCAAAACACTGGAATTACAAATGAGAAGAGTCTACAATAAATTAAGATTTTTGAATTTGTACTTCTGCGGTGCTGGTTTTT
CTCCACAAACACCCCCGCCCCTCCCCATGCCCAGGGTGGCCGTGGAAGGGACGGTTTACGGACGTGCAGCTGAGCTGTCCGTGTCCCATG
CTCCCTCAGCCAGTGGAACGTGCCGGAACTTTTTGTCCATTCCCTAGTAGGCCTGCCACAGCCTAGATGGGCAGTTTTTGTCTTTCACCA
AATTTGAGGACTTTTTTTTTTTGCCATTATTTCTTCAGTTTTCTTTTCTTGCACTGATCTTTCTCCTCTCCTTCTGTGACTCCAGTGACT
CAGACGTTAGACCTCTTGATGTTTTCCCACTGGTCCCTGAGGCTCTGTTCGCATCTTGAAAAATAAAGTCACCTACCCGCCGCCGCTGAC
GCTGACGGAGCAGACGCTGAAGGGCCGGCTCCGGGAGAAGCTGGCCGACTGTGAGCAGAGCCCCACATCCTCGCGCACGTCTTCCCTGGG
CTCTGGCGGCCCCGACTGCGCCATCACAGTCAAGAGCCCTGGGAGGGAGCCGGGGCGTGACCACCTCAACGGGGTGGCCATGAATGTGCG
CACTGGGAGCGCCCAGGCCGATGGCTCCGACTCTGAGGGACGCTGTGGCCAACCACGTTCCGGCCGGCTGGCCCGACCAGAGCCTGGCTG
AGAGTGACAGTGAGGACCCCAGCGGCAAGCCCCGCCTGAAGGTGGAGACCAAGGTCAGCGTGGAGCTGCACCGCGAGGAGCAGGGCAGTC
ACCGTGGAGAGTACCCCCCGGACCAGGAGAGCGGGGGCGCAGCCAGGCTTGCTAGCAGCCAGCCCCCAGAGCAGAGGAAAGGCCACGATT
CCGACTCAGATAGCGAGCTGTCCCTGGATGAGCAGAGCAGCTCTTACGCCTCCTCACACTCGTCAGACAGCGAGGACGATGGGGTGGGAG
CTGAGGAAAAATGGGACCCGGCCAGGGGCGCCGTCCACAGCACCCCCAAAGGGATGAAGGGATCCAGAAGCTCGGCGTGTCCTCTGGGCT
GGTGAGGGGCAGCCACGGAGAGCCAGACGCGTCCCTCATGCCCAGGAGCTGCAAGGATCCCCCTGCGCTCCCTCAACTGCAACACCACCT
TCGGTGACGGGCCTGACATGCTGCGCACAGACTTGGGCGAGTCCACCGCCTCGCTGGACAGCATCGTCAGGGCCCCTTCGTCCTCCTTTT
CCACTGCGTGCTCAACCAGGAGGTCCGGAAGCACCTGAAGGGCGTGCTCGGCGGGAGGAAGCTGCACCTGGAGGACTCCGCCACCACCAG
GGCCACCCTGCTGACGCTCCCTGCTGAGGACCGCATTCCTCCTGCTGCTGCTCATCAGCGCCACCTGGCTGCTGGGGCTGCTGGCTGTGA
ACCGCGATGCACTGAGCTTTCACTACCTCTTCGCCATCTTCAGCGGCTTACAGATCAACACAGTCACTTCTGTCCTATCTGCAAAGGTTT
CCTGCCAAAGAAAGCACCATTATTATGGGAAAAAAGGGATCGTGACTGGCGGTCGGCCTGGACCCCCAGGGCTACGGGAACCCCGACTTC
TGCTGGCTGTCGCTTCAAGACACCCTGATTTGGAGCTTTGCGGGGCCCATCGGAGCTGTTATAATCTTTCTGTGCACAGTGGTTGCCATC
CTCCTCCACTACATCTACATGAGCACCTTTGCCTGGACCCTCGTGGAGAGCCTGCATGTCTACCGCATGCTGACCGAGGTGCGCAACATC
GACACGGGGCCCATGCGGTTCTACTACGTCGTGGGCTGGGGCATCCCGGCCATTGTCACAGAACGGGGAGGTCCTGCCTCTGAAGATTGT
CACCTATGCCGCTGTGTCCTTGTCACTGGCAGCCCTGCTGGTGGCCTTCGTCCTCCTGAGCCTGGTCCGCATGCTGCGCTCCAACCTGCA
CAGCATTCACAAGCACCTCGCCGTGGCGCTCTTCCTCTCTCAGCTGGTGTTCGTGATTGGGATCAACCAGACGGAAAACCCGCGTTGGTG
GGACGGGAGGGTGGTCTGCCCGGGGCTGCGAGCTCCTGTCCAGGAACCGGACACATGTCGCCTGCCAGTGCAGCCACACAGCCAGCTTTG
CGGTGCTCATGGATATCTCCAGGCGTGAGGTTGCCTCACCGGCCCATCATTAATACCCCGATGGTGAGCACGCTGGTGTACAGCGAGGGG
GCTCCGCTCCCGAGACCCCTGGAGAGGCCCGTCCTGGTGGAGTTCGCCCTGCTGGAGGTGGAGGAGCGAACCAAGCCTGTCTGCGTGTTC
TGGAACCACTCCCTGGCAAGGCCCCCTGCTGAGGCCGGCTGGCCGGAGGACCACCCCGCAGACCACGCGCCCGGGGCCTGGCACCGAGAG
GGAGGCCCCGATCAGCAGGCGGAGGCGACACCCTGATGACGCTGGCCAGTTCGCCGTCGCTCTGGTCATCATTTACCGCACCCTGGGGCA
GCTCCTGCCCGAGCGCTACGACCCCGACCGTCGCAGCCTCCGTTCTTGCTGTCGACATCTTTGACAAGTTCAACTTTACGGGAGCCAGGG
TCCCGCGATTCGACACCATCCATGAAGAGTTCCCCAGGGAGCTGGAGTCCTCCGTCTCCTTCCCAGCCGACTTCTTCAGACCACCTGAAG
AAAAAGGACGTCATCCACTCGGGCAGCGCCCTCCTGGCCCCAGCCACCAGGGCGGCGTGGGAGCAGATCCAGCGGAGCGAGGGCGGCACG
GCACAGCTGCTCCGGCGCCTCGAGGGCTACTTCAGCAACGTGGCACGCAACGTGCGGCGGACGTACCTGCGGCCCTTCGTCATCGTCACC
GCCAACATGAAATGAGAAGCTGAGCCGCAATGAGACGCAGGTGGACGGCGCCAGGGCCCTGCAGCTGGTGAGGGCGCTGCGCAGTGCTAC
ACAGCACACGGGCACGCTCTTTGGCAATGACGTGCGCACGGCCTACCAGCTGCTGGGCCACGTCCTTCAGCACGAGAGCTGGCAGCAGGG
CTTCGACCTGGCAGCCACGCAGGACGCCGACTTTCACGAGGAAATGCGGTCCGACACTGCAGCGGGGAGAAGGGCTGGCTGCCCCCAGAG
CTCTTTAACTGTACCACCATCTCCTTCGTGGACCTCAGGGCCATGTGATCTACAATGGCTGTCCCAAAGCATTTGAGGCCGGCATCTGGT
GGCCACAGACCAAGTTCGGGCAGCCGGCTGCGGTGCCATGCCCTAAGGGATCCGTTGGAGAATTACTACAAGCTCCTAGCCCAGGACACC
TGTCTGCCCTGCGACTGCTTCCCCCATGGCTCCCACAGCCGCACTTGCGACATGGCCACCGGGCAGTGTGCCTGCAAGCCCGGCGTCATC
GGCCGCCAGTGCAACCGCTGCGACAACCCGTTTGCCGAGGTCACCACGCTCGGCTGTGAAGACTCGACCTTCCGTGCCCCAGAGGCTGGT
GGGGGAACCCCGTCTGTGGACCCTGCCACTGTGCCGTCAGCAAAGGCTTTGATCCCGACTGTAATAAGACCAACGGCCAGTGCCAATGCA
AGCTGTGTGGATGCCTGTCACCTGAACCCCTGCGAGAACATGGGGGCCTGCGTGCGCTCCCCCGGCTCCCCGCAGGGCTACGTGTGCGAG

>22311_22311_5_DEPDC5-CELSR1_DEPDC5_chr22_32275603_ENST00000400248_CELSR1_chr22_46792627_ENST00000262738_length(amino acids)=1309AA_BP=1275
MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKEDLQKETISVDQTVTQVFRLRPYQDVYVNVV
DPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRASIRQDHKGRFYEDFYKVVVQNERREEWTSL
LVTIKKLFIQYPVLVRLEQAEGFPQGDNSTSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFTPRIKLAGKKPASEKAKNGRDTSLGSPKESE
NALPIQVDYDAYDAQVFRLPGPSRAQCLTTCRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAI
QIHHQTRQNMAELQGSGQRDPTHSSAELLELAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
PDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDEDGVQMTAQQVFEEFICQRLMQGYQIIVQPKT
QKPNPAVPPPLSSSPLYSRGLVSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFS
HERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIYGDRPRADEDEWQLLDGFVRFVEGLNRIRRR
HRSDRMMRKGTAMKGLQMTGPISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRKV
SVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSSSQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLS
PYCFISAEVVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRAEELVHSEIPAFLLPWLPSRPAS

--------------------------------------------------------------
>22311_22311_6_DEPDC5-CELSR1_DEPDC5_chr22_32275603_ENST00000400249_CELSR1_chr22_46792627_ENST00000262738_length(transcript)=9661nt_BP=3989nt
ATCTGGAGGAGGCGCAGGGAACCTGGAGAGGGTCCAGCCCTCAGTGCCCCGGCCAGAGGCGGGAAGGGGCTCTAGAGCTTCGGGAGGCAA
GATGACTTCTCTGCCCCAAGCTTGGAACAGCTAAAGGGAAAAACAGTGCAAGATGAGAACAACAAAGGTCTACAAACTCGTCATCCACAA
GAAGGGCTTTGGGGGCAGTGATGATGAGCTAGTTGTGAACCCCAAAGTGTTCCCTCACATCAAGCTTGGAGACATTGTAGAGATTGCACA
CCCCAACGATGAATACAGCCCTCTGCTTTTGCAGGTCAAGTCTCTTAAGGAAGATTTACAGAAGGAAACTATCAGTGTGGACCAGACTGT
GACTCAAGTGTTCCGGCTGAGACCTTATCAGGATGTCTATGTTAATGTCGTAGACCCTAAGGATGTGACCCTTGACCTAGTGGAATTAAC
TTTTAAGGATCAGTATATTGGCCGTGGGGATATGTGGCGACTAAAGAAAAGTTTGGTCAGCACATGTGCCTATATCACCCAGAAGGTGGA
GTTTGCTGGCATCAGAGCACAGGCTGGTGAACTGTGGGTTAAGAATGAGAAGGTCATGTGTGGCTACATCAGTGAAGATACCAGGGTGGT
GTTTCGTTCTACGTCGGCTATGGTTTACATATTTATTCAGATGAGCTGTGAAATGTGGGATTTTGATATTTATGGGGATTTGTATTTTGA
GAAAGCTGTGAATGGTTTCCTTGCTGATCTATTTACCAAGTGGAAGGAGAAGAACTGTAGTCATGAAGTGACAGTGGTCCTGTTTTCTAG
AACTTTCTATGATGCAAAATCTGTTGATGAATTTCCTGAAATAAACCGAGCCTCAATTCGACAGGATCACAAGGGGAGATTCTATGAAGA
CTTTTACAAAGTGGTGGTGCAGAATGAGAGAAGAGAAGAATGGACTTCACTTCTCGTAACCATTAAAAAACTCTTCATCCAGTATCCAGT
GTTGGTGCGACTGGAACAGGCAGAGGGCTTTCCTCAAGGAGATAATTCTACCTCAGCACAAGGAAACTACCTGGAGGCCATCAATCTGTC
ATTCAATGTGTTTGATAAGCACTACATCAACCGCAACTTTGACCGAACTGGGCAGATGTCAGTGGTGATCACGCCCGGGGTGGGTGTCTT
TGAAGTGGACCGCCTACTCATGATCCTGACCAAGCAGCGGATGATAGATAATGGAATTGGTGTGGATTTGGTGTGCATGGGAGAGCAACC
GTTACATGCTGTCCCATTGTTCAAGCTCCATAATCGGAGTGCTCCCCGTGATTCTCGTCTGGGCGATGACTATAATATCCCTCACTGGAT
AAACCACAGTTTCTACACATCCAAAAGCCAGCTCTTTTGTAATAGTTTCACCCCACGAATAAAACTGGCAGGAAAGAAGCCCGCCTCTGA
GAAAGCAAAAAATGGCCGTGATACATCTCTCGGGAGTCCAAAAGAATCTGAGAACGCCCTTCCCATCCAAGTAGATTATGACGCCTATGA
CGCTCAAGTGTTCAGGCTGCCCGGCCCATCCCGGGCCCAGTGCCTCACCACCTGCAGATCTGTGCGAGAGCGAGAGAGTCACAGTCGAAA
GAGTGCCAGCTCCTGTGATGTTTCATCCAGCCCTTCCCTACCAAGCCGCACACTGCCCACTGAGGAAGTGAGGAGCCAGGCTTCTGACGA
CAGCTCCCTAGGCAAGAGTGCCAACATCCTGATGATCCCACACCCCCACCTGCACCAGTATGAAGTCAGCAGCTCCTTGGGATACACCAG
CACTCGAGATGTCCTGGAGAACATGATGGAGCCACCACAGCGAGACTCCAGTGCACCAGGGAGGTTTCACGTTGGCAGTGCAGAATCCAT
GCTGCATGTTCGACCTGGTGGATACACGCCCCAGAGAGCACTGATTAACCCCTTCGCTCCCTCTCGGATGCCCATGAAGCTTACGTCCAA
CAGAAGGCGCTGGATGCACACTTTTCCTGTGGGGCCATCCGGAGAAGCCATCCAGATCCACCACCAGACCCGACAGAATATGGCGGAGCT
ACAAGGCAGCGGGCAGAGGGATCCAACTCACTCCTCTGCAGAGCTGCTGGAGTTAGCATATCATGAAGCTGCTGGAAGGCACAGCAATTC
CCGCCAGCCTGGTGACGGCATGTCCTTCTTGAACTTCAGTGGAACAGAGGAGCTTTCTGTCGGCCTGCTTAGCAACAGTGGTGCAGGTAT
GAATCCTAGGACCCAGAATAAGGATTCTCTAGAGGACAGTGTTTCTACCTCTCCAGACCCAATGCCAGGCTTCTGTTGCACAGTTGGAGT
GGACTGGAAGTCTCTCACTACTCCGGCGTGCCTCCCCCTTACCACCGACTACTTCCCTGACCGCCAGGGCCTGCAGAATGACTACACAGA
GGGCTGTTATGATCTCCTTCCAGAAGCAGACATCGACAGGAGGGACGAAGATGGTGTGCAGATGACAGCCCAGCAGGTATTTGAAGAGTT
TATTTGCCAACGTCTCATGCAGGGCTACCAAATCATAGTGCAGCCCAAGACACAGAAACCCAATCCTGCTGTCCCGCCCCCGCTGAGCAG
TAGCCCACTCTATAGCCGAGGCCTTGTGTCCCGAAACCGCCCTGAGGAGGAGGACCAGTATTGGCTGAGTATGGGCAGAACGTTCCACAA
AGTGACGCTGAAGGATAAGATGATCACAGTGACGCGATACCTTCCCAAGTATCCTTATGAATCTGCCCAGATCCACTACACCTACAGCCT
CTGTCCTTCCCACTCAGACTCAGAGTTCGTCTCCTGCTGGGTGGAATTCTCCCACGAACGGCTGGAGGAGTACAAGTGGAATTACTTAGA
TCAGTATATCTGTTCTGCCGGCTCTGAAGACTTCAGCTTAATTGAGTCCCTGAAGTTCTGGAGGACCCGCTTCCTGCTGCTGCCAGCCTG
TGTCACCGCCACCAAGCGCATCACGGAGGGGGAGGCCCACTGCGACATCTATGGGGACAGGCCCCGTGCAGACGAGGACGAGTGGCAACT
CCTGGATGGTTTTGTCCGCTTTGTGGAGGGCTTGAATCGCATTCGCAGGCGGCATCGCTCGGATCGCATGATGCGGAAAGGGACCGCCAT
GAAAGGCTTGCAGATGACTGGGCCCATTTCCACGCATTCTCTGGAGTCAACTGCACCCCCAGTGGGGAAGAAGGGAACCTCAGCTCTCTC
TGCCCTGTTGGAGATGGAGGCCAGTCAGAAGTGCCTGGGAGAACAGCAGGCAGCTGTGCATGGTGGGAAGAGCTCCGCCCAGTCAGCCGA
GAGCAGCAGCGTTGCCATGACTCCCACCTACATGGACAGCCCACGAAAGGTATCTGTGGACCAAACAGCCACTCCTATGTTGGACGGCAC
CAGTTTGGGCATATGCACAGGCCAATCCATGGACAGAGGCAACAGCCAGACCTTTGGGAACTCCCAGAACATAGGAGAACAGGGCTACTC
CTCCACAAACTCCAGTGACAGCAGCTCTCAGCAGCTGGTGGCAAGCTCCTTGACCTCATCCTCTACCCTGACAGAGATCCTGGAAGCCAT
GAAGCACCCCTCGACAGGAGTCCAGCTGCTCTCTGAACAGAAGGGCCTCTCACCGTACTGCTTCATCAGCGCGGAGGTGGTACACTGGTT
GGTGAACCACGTGGAGGGGATCCAGACACAGGCGATGGCCATTGACATCATGCAGAAAATGCTGGAAGAGCAGCTCATCACACATGCATC
TGGCGAAGCCTGGCGGACCTTCATCTACGGCTTCTATTTCTACAAGATAGTAACGGACAAAGAGCCCGACCGAGCAGAAGAGCTCGTGCA
CTCTGAGATTCCTGCCTTTCTCCTGCCCTGGCTGCCTAGCCGGCCAGCCTCCTATGCAAGTAGGCACAGCTCCTTTAGCCGAAGTTTTGG
AGGACGGAGCCAGGCGGCAGCACTTTTAGGAAACCGTGAGGCAAGCCCGTCACCCCACACAGGCTGCGGCATCACCCTCAGACCTTGGAG
CCCAAGGGGCCACTGCCCTTGAAGTGGAGTGGGCCCAGAGTGTGGCGGTCCCCATGGTGGCAGCCCCCCGACTGATCATCCAGACACAAA
GGTCTTGGTTCTCCCAGGAGCTCAGGGCCTGTCAGACCTGGTGACAAGTGCCAAAGGCCACAGGCATGAGGGAGGCGTGGACCACTGGGC
CAGCACCGCTGAGTCCTAAGACTGCAGTCAAAGCCAGAACTGAGAGGGGACCCCAGACTGGGCCCAGAGGCTGGCCAGAGTTCAGGAACG
CCGGGCACAGACCAAAGACCGCGGTCCAGCCCCGCCCAGGCGGGCATCTCATGGCAGTGCGGACCCGTGGCTGGCAGCCCGGGCAGTCCT
TTGCAAAGGCACCCCTTGTCTTAAAATCACTTCGCTATGTGGGAAAGGTGGAGATACTTTTATATATTTGTATGGGACTCTGAGGAGGTG
CAACCTGTATATATATTGCATTCGTGCTGACTTTGTTATCCCGAGAGATCCATGCAATGATCTCTTGCTGTCTTCTCTGTCAAGATTGCA
CAGTTGTACTTGAATCTGGCATGTGTTGACGAAACTGGTGCCCCAGCAGATCAAAGGTGGGAAATACGTCAGCAGTGGGGCTAAAACCAA
GCGGCTAGAAGCCCTACAGCTGCCTTCGGCCAGGAAGTGAGGATGGTGTGGGCCCTCCCCGCCGGCCCCCTGGGTCCCCAGTGTTCGCTG
TGTGTGCGTTTGTCCTCTGCTGCCATCTGCCCCGGCTGTGTGAATTCAAGACAGGGCAGTGCAGCACTAGGCAGGTGTGAGGAGCCCTGC
TGAGGTCACTGTGGGGCACGGTTGCCACACGGCTGTCATTTTTCACCTGGTCATTCTGTGACCACCACCCCCTCCCCTCACCGCCTCCCA
GGTGGCCCGGGAGCTGCAGGTGGGGATGGCTTTGTCCTTTGCTCCTGCTCCCCGTGGGACCTGGGACCTTAAAGCGTTGCAGGTTCCTGA
TTTGGACAGAGGTGTGGGGCCTTCCAGGCCGTTACATACCTCCTGCCAATTCTCTAACTCTCTGAGACTGCGAGGATCTCCAGGCAGGGT
TCTCCCCTCTGGAGTCTGACCAATTACTTCATTTTGCTTCAAATGGCCAATTGTGCAGAGGGACAAAGCCACAGCCACACTCTTCAACGG
TTACCAAACTGTTTTTGGAAATTCACACCAAGGTCGGGCCCACTGCAGGCAGCTGGCACAGCGTGGCCCGAGGGGCTGTGGAACGGGTCC
CGGAACTGTCAGACATGTTTGATTTTAGCGTTTCCTTTGTTCTTCAAATCAGGTGCCCAAATAAGTGATCAGCACAGCTGCTTCCAAATA
GGAGAAACCATAAAATAGGATGAAAATCAAGTAAAATGCAAAGATGTCCACACTGTTTTAAACTTGACCCTGATGAAAATGTGAGCACTG
TTAGCAGATGCCTATGGGAGAGGAAAAGCGTATCTGAAAATGGTCCAGGACAGGAGGATGAAATGAGATCCCAGAGTCCTCACACCTGAA
TGAATTATACATGTGCCTTACCAGGTGAGTGGTCTTTCGAAGATAAAAAACTCTAGTCCCTTTAAACGTTTGCCCCTGGCGTTTCCTAAG
TACGAAAAGGTTTTTAAGTCTTCGAACAGTCTCCTTTCATGACTTTAACAGGATTCTGCCCCCTGAGGTGTAATTTTTTTGTTCTATTTT
TTTCCACGTACTCCACAGCCAACATCACGAGGTGTAATTTTTAATTTGATCAGAACTGTTACCAAAAAACAACTGTCAGTTTTATTGAGA
TGGGAAAAATGTAAACCTATTTTTATTACTTAAGACTTTATGGGAGAGATTAGACACTGGAGGTTTTTAACAGAACGTGTATTTATTAAT
GTTCAAAACACTGGAATTACAAATGAGAAGAGTCTACAATAAATTAAGATTTTTGAATTTGTACTTCTGCGGTGCTGGTTTTTCTCCACA
AACACCCCCGCCCCTCCCCATGCCCAGGGTGGCCGTGGAAGGGACGGTTTACGGACGTGCAGCTGAGCTGTCCGTGTCCCATGCTCCCTC
AGCCAGTGGAACGTGCCGGAACTTTTTGTCCATTCCCTAGTAGGCCTGCCACAGCCTAGATGGGCAGTTTTTGTCTTTCACCAAATTTGA
GGACTTTTTTTTTTTGCCATTATTTCTTCAGTTTTCTTTTCTTGCACTGATCTTTCTCCTCTCCTTCTGTGACTCCAGTGACTCAGACGT
TAGACCTCTTGATGTTTTCCCACTGGTCCCTGAGGCTCTGTTCGCATCTTGAAAAATAAAGTCACCTACCCGCCGCCGCTGACGCTGACG
GAGCAGACGCTGAAGGGCCGGCTCCGGGAGAAGCTGGCCGACTGTGAGCAGAGCCCCACATCCTCGCGCACGTCTTCCCTGGGCTCTGGC
GGCCCCGACTGCGCCATCACAGTCAAGAGCCCTGGGAGGGAGCCGGGGCGTGACCACCTCAACGGGGTGGCCATGAATGTGCGCACTGGG
AGCGCCCAGGCCGATGGCTCCGACTCTGAGGGACGCTGTGGCCAACCACGTTCCGGCCGGCTGGCCCGACCAGAGCCTGGCTGAGAGTGA
CAGTGAGGACCCCAGCGGCAAGCCCCGCCTGAAGGTGGAGACCAAGGTCAGCGTGGAGCTGCACCGCGAGGAGCAGGGCAGTCACCGTGG
AGAGTACCCCCCGGACCAGGAGAGCGGGGGCGCAGCCAGGCTTGCTAGCAGCCAGCCCCCAGAGCAGAGGAAAGGCCACGATTCCGACTC
AGATAGCGAGCTGTCCCTGGATGAGCAGAGCAGCTCTTACGCCTCCTCACACTCGTCAGACAGCGAGGACGATGGGGTGGGAGCTGAGGA
AAAATGGGACCCGGCCAGGGGCGCCGTCCACAGCACCCCCAAAGGGATGAAGGGATCCAGAAGCTCGGCGTGTCCTCTGGGCTGGTGAGG
GGCAGCCACGGAGAGCCAGACGCGTCCCTCATGCCCAGGAGCTGCAAGGATCCCCCTGCGCTCCCTCAACTGCAACACCACCTTCGGTGA
CGGGCCTGACATGCTGCGCACAGACTTGGGCGAGTCCACCGCCTCGCTGGACAGCATCGTCAGGGCCCCTTCGTCCTCCTTTTCCACTGC
GTGCTCAACCAGGAGGTCCGGAAGCACCTGAAGGGCGTGCTCGGCGGGAGGAAGCTGCACCTGGAGGACTCCGCCACCACCAGGGCCACC
CTGCTGACGCTCCCTGCTGAGGACCGCATTCCTCCTGCTGCTGCTCATCAGCGCCACCTGGCTGCTGGGGCTGCTGGCTGTGAACCGCGA
TGCACTGAGCTTTCACTACCTCTTCGCCATCTTCAGCGGCTTACAGATCAACACAGTCACTTCTGTCCTATCTGCAAAGGTTTCCTGCCA
AAGAAAGCACCATTATTATGGGAAAAAAGGGATCGTGACTGGCGGTCGGCCTGGACCCCCAGGGCTACGGGAACCCCGACTTCTGCTGGC
TGTCGCTTCAAGACACCCTGATTTGGAGCTTTGCGGGGCCCATCGGAGCTGTTATAATCTTTCTGTGCACAGTGGTTGCCATCCTCCTCC
ACTACATCTACATGAGCACCTTTGCCTGGACCCTCGTGGAGAGCCTGCATGTCTACCGCATGCTGACCGAGGTGCGCAACATCGACACGG
GGCCCATGCGGTTCTACTACGTCGTGGGCTGGGGCATCCCGGCCATTGTCACAGAACGGGGAGGTCCTGCCTCTGAAGATTGTCACCTAT
GCCGCTGTGTCCTTGTCACTGGCAGCCCTGCTGGTGGCCTTCGTCCTCCTGAGCCTGGTCCGCATGCTGCGCTCCAACCTGCACAGCATT
CACAAGCACCTCGCCGTGGCGCTCTTCCTCTCTCAGCTGGTGTTCGTGATTGGGATCAACCAGACGGAAAACCCGCGTTGGTGGGACGGG
AGGGTGGTCTGCCCGGGGCTGCGAGCTCCTGTCCAGGAACCGGACACATGTCGCCTGCCAGTGCAGCCACACAGCCAGCTTTGCGGTGCT
CATGGATATCTCCAGGCGTGAGGTTGCCTCACCGGCCCATCATTAATACCCCGATGGTGAGCACGCTGGTGTACAGCGAGGGGGCTCCGC
TCCCGAGACCCCTGGAGAGGCCCGTCCTGGTGGAGTTCGCCCTGCTGGAGGTGGAGGAGCGAACCAAGCCTGTCTGCGTGTTCTGGAACC
ACTCCCTGGCAAGGCCCCCTGCTGAGGCCGGCTGGCCGGAGGACCACCCCGCAGACCACGCGCCCGGGGCCTGGCACCGAGAGGGAGGCC
CCGATCAGCAGGCGGAGGCGACACCCTGATGACGCTGGCCAGTTCGCCGTCGCTCTGGTCATCATTTACCGCACCCTGGGGCAGCTCCTG
CCCGAGCGCTACGACCCCGACCGTCGCAGCCTCCGTTCTTGCTGTCGACATCTTTGACAAGTTCAACTTTACGGGAGCCAGGGTCCCGCG
ATTCGACACCATCCATGAAGAGTTCCCCAGGGAGCTGGAGTCCTCCGTCTCCTTCCCAGCCGACTTCTTCAGACCACCTGAAGAAAAAGG
ACGTCATCCACTCGGGCAGCGCCCTCCTGGCCCCAGCCACCAGGGCGGCGTGGGAGCAGATCCAGCGGAGCGAGGGCGGCACGGCACAGC
TGCTCCGGCGCCTCGAGGGCTACTTCAGCAACGTGGCACGCAACGTGCGGCGGACGTACCTGCGGCCCTTCGTCATCGTCACCGCCAACA
TGAAATGAGAAGCTGAGCCGCAATGAGACGCAGGTGGACGGCGCCAGGGCCCTGCAGCTGGTGAGGGCGCTGCGCAGTGCTACACAGCAC
ACGGGCACGCTCTTTGGCAATGACGTGCGCACGGCCTACCAGCTGCTGGGCCACGTCCTTCAGCACGAGAGCTGGCAGCAGGGCTTCGAC
CTGGCAGCCACGCAGGACGCCGACTTTCACGAGGAAATGCGGTCCGACACTGCAGCGGGGAGAAGGGCTGGCTGCCCCCAGAGCTCTTTA
ACTGTACCACCATCTCCTTCGTGGACCTCAGGGCCATGTGATCTACAATGGCTGTCCCAAAGCATTTGAGGCCGGCATCTGGTGGCCACA
GACCAAGTTCGGGCAGCCGGCTGCGGTGCCATGCCCTAAGGGATCCGTTGGAGAATTACTACAAGCTCCTAGCCCAGGACACCTGTCTGC
CCTGCGACTGCTTCCCCCATGGCTCCCACAGCCGCACTTGCGACATGGCCACCGGGCAGTGTGCCTGCAAGCCCGGCGTCATCGGCCGCC
AGTGCAACCGCTGCGACAACCCGTTTGCCGAGGTCACCACGCTCGGCTGTGAAGACTCGACCTTCCGTGCCCCAGAGGCTGGTGGGGGAA
CCCCGTCTGTGGACCCTGCCACTGTGCCGTCAGCAAAGGCTTTGATCCCGACTGTAATAAGACCAACGGCCAGTGCCAATGCAAGCTGTG
TGGATGCCTGTCACCTGAACCCCTGCGAGAACATGGGGGCCTGCGTGCGCTCCCCCGGCTCCCCGCAGGGCTACGTGTGCGAGTGTGGGC

>22311_22311_6_DEPDC5-CELSR1_DEPDC5_chr22_32275603_ENST00000400249_CELSR1_chr22_46792627_ENST00000262738_length(amino acids)=1309AA_BP=1275
MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKEDLQKETISVDQTVTQVFRLRPYQDVYVNVV
DPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRASIRQDHKGRFYEDFYKVVVQNERREEWTSL
LVTIKKLFIQYPVLVRLEQAEGFPQGDNSTSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFTPRIKLAGKKPASEKAKNGRDTSLGSPKESE
NALPIQVDYDAYDAQVFRLPGPSRAQCLTTCRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGPSGEAI
QIHHQTRQNMAELQGSGQRDPTHSSAELLELAYHEAAGRHSNSRQPGDGMSFLNFSGTEELSVGLLSNSGAGMNPRTQNKDSLEDSVSTS
PDPMPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDEDGVQMTAQQVFEEFICQRLMQGYQIIVQPKT
QKPNPAVPPPLSSSPLYSRGLVSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHYTYSLCPSHSDSEFVSCWVEFS
HERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIYGDRPRADEDEWQLLDGFVRFVEGLNRIRRR
HRSDRMMRKGTAMKGLQMTGPISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSAQSAESSSVAMTPTYMDSPRKV
SVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSSSQQLVASSLTSSSTLTEILEAMKHPSTGVQLLSEQKGLS
PYCFISAEVVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRAEELVHSEIPAFLLPWLPSRPAS

--------------------------------------------------------------
>22311_22311_7_DEPDC5-CELSR1_DEPDC5_chr22_32275603_ENST00000535622_CELSR1_chr22_46792627_ENST00000262738_length(transcript)=9390nt_BP=3718nt
AGCGGCGCGGGTTCTCAGGGAGGCAAGATGACTTCTCTGCCCCAAGCTTGGAACAGCTAAAGGGAAAAACAGTGCAAGATGAGAACAACA
AAGGTCTACAAACTCGTCATCCACAAGAAGGGCTTTGGGGGCAGTGATGATGAGCTAGTTGTGAACCCCAAAGTGTTCCCTCACATCAAG
CTTGGAGACATTGTAGAGATTGCACACCCCAACGATGAATACAGCCCTCTGCTTTTGCAGGTCAAGTCTCTTAAGGAAGATTTACAGAAG
GAAACTATCAGTGTGGACCAGACTGTGACTCAAGTGTTCCGGCTGAGACCTTATCAGGATGTCTATGTTAATGTCGTAGACCCTAAGGAT
GTGACCCTTGACCTAGTGGAATTAACTTTTAAGGATCAGTATATTGGCCGTGGGGATATGTGGCGACTAAAGAAAAGTTTGGTCAGCACA
TGTGCCTATATCACCCAGAAGGTGGAGTTTGCTGGCATCAGAGCACAGGCTGGTGAACTGTGGGTTAAGAATGAGAAGGTCATGTGTGGC
TACATCAGTGAAGATACCAGGGTGGTGTTTCGTTCTACGTCGGCTATGGTTTACATATTTATTCAGATGAGCTGTGAAATGTGGGATTTT
GATATTTATGGGGATTTGTATTTTGAGAAAGCTGTGAATGGTTTCCTTGCTGATCTATTTACCAAGTGGAAGGAGAAGAACTGTAGTCAT
GAAGTGACAGTGGTCCTGTTTTCTAGAACTTTCTATGATGCAAAATCTGTTGATGAATTTCCTGAAATAAACCGAGCCTCAATTCGACAG
GATCACAAGGGGAGATTCTATGAAGACTTTTACAAAGTGGTGGTGCAGAATGAGAGAAGAGAAGAATGGACTTCACTTCTCGTAACCATT
AAAAAACTCTTCATCCAGTATCCAGTGTTGGTGCGACTGGAACAGGCAGAGGGCTTTCCTCAAGGAGATAATTCTACCTCAGCACAAGGA
AACTACCTGGAGGCCATCAATCTGTCATTCAATGTGTTTGATAAGCACTACATCAACCGCAACTTTGACCGAACTGGGCAGATGTCAGTG
GTGATCACGCCCGGGGTGGGTGTCTTTGAAGTGGACCGCCTACTCATGATCCTGACCAAGCAGCGGATGATAGATAATGGAATTGGTGTG
GATTTGGTGTGCATGGGAGAGCAACCGTTACATGCTGTCCCATTGTTCAAGCTCCATAATCGGAGTGCTCCCCGTGATTCTCGTCTGGGC
GATGACTATAATATCCCTCACTGGATAAACCACAGTTTCTACACATCCAAAAGCCAGCTCTTTTGTAATAGTTTCACCCCACGAATAAAA
CTGGCAGGAAAGAAGCCCGCCTCTGAGAAAGCAAAAAATGGCCGTGATACATCTCTCGGGAGTCCAAAAGAATCTGAGAACGCCCTTCCC
ATCCAAGTAGATTATGACGCCTATGACGCTCAAGTGTTCAGGCTGCCCGGCCCATCCCGGGCCCAGTGCCTCACCACCTGCAGATCTGTG
CGAGAGCGAGAGAGTCACAGTCGAAAGAGTGCCAGCTCCTGTGATGTTTCATCCAGCCCTTCCCTACCAAGCCGCACACTGCCCACTGAG
GAAGTGAGGAGCCAGGCTTCTGACGACAGCTCCCTAGGCAAGAGTGCCAACATCCTGATGATCCCACACCCCCACCTGCACCAGTATGAA
GTCAGCAGCTCCTTGGGATACACCAGCACTCGAGATGTCCTGGAGAACATGATGGAGCCACCACAGCGAGACTCCAGTGCACCAGGGAGG
TTTCACGTTGGCAGTGCAGAATCCATGCTGCATGTTCGACCTGGTGGATACACGCCCCAGAGAGCACTGATTAACCCCTTCGCTCCCTCT
CGGATGCCCATGAAGCTTACGTCCAACAGAAGGCGCTGGATGCACACTTTTCCTGTGGGTATGAATCCTAGGACCCAGAATAAGGATTCT
CTAGAGGACAGTGTTTCTACCTCTCCAGACCCAATTCTGACACTGTCTGCTCCCCCTGTAGTGCCAGGCTTCTGTTGCACAGTTGGAGTG
GACTGGAAGTCTCTCACTACTCCGGCGTGCCTCCCCCTTACCACCGACTACTTCCCTGACCGCCAGGGCCTGCAGAATGACTACACAGAG
GGCTGTTATGATCTCCTTCCAGAAGCAGACATCGACAGGAGGGACGAAGATGGTGTGCAGATGACAGCCCAGCAGGTATTTGAAGAGTTT
ATTTGCCAACGTCTCATGCAGGGCTACCAAATCATAGTGCAGCCCAAGACACAGAAACCCAATCCTGCTGTCCCGCCCCCGCTGAGCAGT
AGCCCACTCTATAGCCGAGGCCTTGTGTCCCGAAACCGCCCTGAGGAGGAGGACCAGTATTGGCTGAGTATGGGCAGAACGTTCCACAAA
GTGACGCTGAAGGATAAGATGATCACAGTGACGCGATACCTTCCCAAGTATCCTTATGAATCTGCCCAGATCCACTACACCTACAGCCTC
TGTCCTTCCCACTCAGACTCAGAGTTCGTCTCCTGCTGGGTGGAATTCTCCCACGAACGGCTGGAGGAGTACAAGTGGAATTACTTAGAT
CAGTATATCTGTTCTGCCGGCTCTGAAGACTTCAGCTTAATTGAGTCCCTGAAGTTCTGGAGGACCCGCTTCCTGCTGCTGCCAGCCTGT
GTCACCGCCACCAAGCGCATCACGGAGGGGGAGGCCCACTGCGACATCTATGGGGACAGGCCCCGTGCAGACGAGGACGAGTGGCAACTC
CTGGATGGTTTTGTCCGCTTTGTGGAGGGCTTGAATCGCATTCGCAGGCGGCATCGCTCGGATCGCATGATGCGGAAAGGGACCGCCATG
AAAGGCTTGCAGATGACTGGGCCCATTTCCACGCATTCTCTGGAGTCAACTGCACCCCCAGTGGGGAAGAAGGGAACCTCAGCTCTCTCT
GCCCTGTTGGAGATGGAGGCCAGTCAGAAGTGCCTGGGAGAACAGCAGGCAGCTGTGCATGGTGGGAAGAGCTCCGCCCAGTCAGCCGAG
AGCAGCAGCGTTGCCATGACTCCCACCTACATGGACAGCCCACGAAAGGTATCTGTGGACCAAACAGCCACTCCTATGTTGGACGGCACC
AGTTTGGGCATATGCACAGGCCAATCCATGGACAGAGGCAACAGCCAGACCTTTGGGAACTCCCAGAACATAGGAGAACAGGGCTACTCC
TCCACAAACTCCAGTGACAGCAGCTCTCAGCAGCTGGTGGCAAGCTCCTTGACCTCATCCTCTACCCTGACAGAGATCCTGGAAGCCATG
AAGCACCCCTCGACAGGAGTCCAGCTGCTCTCTGAACAGAAGGGCCTCTCACCGTACTGCTTCATCAGCGCGGAGGTGGTACACTGGTTG
GTGAACCACGTGGAGGGGATCCAGACACAGGCGATGGCCATTGACATCATGCAGAAAATGCTGGAAGAGCAGCTCATCACACATGCATCT
GGCGAAGCCTGGCGGACCTTCATCTACGGCTTCTATTTCTACAAGATAGTAACGGACAAAGAGCCCGACCGAGCAGAAGAGCTCGTGCAC
TCTGAGATTCCTGCCTTTCTCCTGCCCTGGCTGCCTAGCCGGCCAGCCTCCTATGCAAGTAGGCACAGCTCCTTTAGCCGAAGTTTTGGA
GGACGGAGCCAGGCGGCAGCACTTTTAGGAAACCGTGAGGCAAGCCCGTCACCCCACACAGGCTGCGGCATCACCCTCAGACCTTGGAGC
CCAAGGGGCCACTGCCCTTGAAGTGGAGTGGGCCCAGAGTGTGGCGGTCCCCATGGTGGCAGCCCCCCGACTGATCATCCAGACACAAAG
GTCTTGGTTCTCCCAGGAGCTCAGGGCCTGTCAGACCTGGTGACAAGTGCCAAAGGCCACAGGCATGAGGGAGGCGTGGACCACTGGGCC
AGCACCGCTGAGTCCTAAGACTGCAGTCAAAGCCAGAACTGAGAGGGGACCCCAGACTGGGCCCAGAGGCTGGCCAGAGTTCAGGAACGC
CGGGCACAGACCAAAGACCGCGGTCCAGCCCCGCCCAGGCGGGCATCTCATGGCAGTGCGGACCCGTGGCTGGCAGCCCGGGCAGTCCTT
TGCAAAGGCACCCCTTGTCTTAAAATCACTTCGCTATGTGGGAAAGGTGGAGATACTTTTATATATTTGTATGGGACTCTGAGGAGGTGC
AACCTGTATATATATTGCATTCGTGCTGACTTTGTTATCCCGAGAGATCCATGCAATGATCTCTTGCTGTCTTCTCTGTCAAGATTGCAC
AGTTGTACTTGAATCTGGCATGTGTTGACGAAACTGGTGCCCCAGCAGATCAAAGGTGGGAAATACGTCAGCAGTGGGGCTAAAACCAAG
CGGCTAGAAGCCCTACAGCTGCCTTCGGCCAGGAAGTGAGGATGGTGTGGGCCCTCCCCGCCGGCCCCCTGGGTCCCCAGTGTTCGCTGT
GTGTGCGTTTGTCCTCTGCTGCCATCTGCCCCGGCTGTGTGAATTCAAGACAGGGCAGTGCAGCACTAGGCAGGTGTGAGGAGCCCTGCT
GAGGTCACTGTGGGGCACGGTTGCCACACGGCTGTCATTTTTCACCTGGTCATTCTGTGACCACCACCCCCTCCCCTCACCGCCTCCCAG
GTGGCCCGGGAGCTGCAGGTGGGGATGGCTTTGTCCTTTGCTCCTGCTCCCCGTGGGACCTGGGACCTTAAAGCGTTGCAGGTTCCTGAT
TTGGACAGAGGTGTGGGGCCTTCCAGGCCGTTACATACCTCCTGCCAATTCTCTAACTCTCTGAGACTGCGAGGATCTCCAGGCAGGGTT
CTCCCCTCTGGAGTCTGACCAATTACTTCATTTTGCTTCAAATGGCCAATTGTGCAGAGGGACAAAGCCACAGCCACACTCTTCAACGGT
TACCAAACTGTTTTTGGAAATTCACACCAAGGTCGGGCCCACTGCAGGCAGCTGGCACAGCGTGGCCCGAGGGGCTGTGGAACGGGTCCC
GGAACTGTCAGACATGTTTGATTTTAGCGTTTCCTTTGTTCTTCAAATCAGGTGCCCAAATAAGTGATCAGCACAGCTGCTTCCAAATAG
GAGAAACCATAAAATAGGATGAAAATCAAGTAAAATGCAAAGATGTCCACACTGTTTTAAACTTGACCCTGATGAAAATGTGAGCACTGT
TAGCAGATGCCTATGGGAGAGGAAAAGCGTATCTGAAAATGGTCCAGGACAGGAGGATGAAATGAGATCCCAGAGTCCTCACACCTGAAT
GAATTATACATGTGCCTTACCAGGTGAGTGGTCTTTCGAAGATAAAAAACTCTAGTCCCTTTAAACGTTTGCCCCTGGCGTTTCCTAAGT
ACGAAAAGGTTTTTAAGTCTTCGAACAGTCTCCTTTCATGACTTTAACAGGATTCTGCCCCCTGAGGTGTAATTTTTTTGTTCTATTTTT
TTCCACGTACTCCACAGCCAACATCACGAGGTGTAATTTTTAATTTGATCAGAACTGTTACCAAAAAACAACTGTCAGTTTTATTGAGAT
GGGAAAAATGTAAACCTATTTTTATTACTTAAGACTTTATGGGAGAGATTAGACACTGGAGGTTTTTAACAGAACGTGTATTTATTAATG
TTCAAAACACTGGAATTACAAATGAGAAGAGTCTACAATAAATTAAGATTTTTGAATTTGTACTTCTGCGGTGCTGGTTTTTCTCCACAA
ACACCCCCGCCCCTCCCCATGCCCAGGGTGGCCGTGGAAGGGACGGTTTACGGACGTGCAGCTGAGCTGTCCGTGTCCCATGCTCCCTCA
GCCAGTGGAACGTGCCGGAACTTTTTGTCCATTCCCTAGTAGGCCTGCCACAGCCTAGATGGGCAGTTTTTGTCTTTCACCAAATTTGAG
GACTTTTTTTTTTTGCCATTATTTCTTCAGTTTTCTTTTCTTGCACTGATCTTTCTCCTCTCCTTCTGTGACTCCAGTGACTCAGACGTT
AGACCTCTTGATGTTTTCCCACTGGTCCCTGAGGCTCTGTTCGCATCTTGAAAAATAAAGTCACCTACCCGCCGCCGCTGACGCTGACGG
AGCAGACGCTGAAGGGCCGGCTCCGGGAGAAGCTGGCCGACTGTGAGCAGAGCCCCACATCCTCGCGCACGTCTTCCCTGGGCTCTGGCG
GCCCCGACTGCGCCATCACAGTCAAGAGCCCTGGGAGGGAGCCGGGGCGTGACCACCTCAACGGGGTGGCCATGAATGTGCGCACTGGGA
GCGCCCAGGCCGATGGCTCCGACTCTGAGGGACGCTGTGGCCAACCACGTTCCGGCCGGCTGGCCCGACCAGAGCCTGGCTGAGAGTGAC
AGTGAGGACCCCAGCGGCAAGCCCCGCCTGAAGGTGGAGACCAAGGTCAGCGTGGAGCTGCACCGCGAGGAGCAGGGCAGTCACCGTGGA
GAGTACCCCCCGGACCAGGAGAGCGGGGGCGCAGCCAGGCTTGCTAGCAGCCAGCCCCCAGAGCAGAGGAAAGGCCACGATTCCGACTCA
GATAGCGAGCTGTCCCTGGATGAGCAGAGCAGCTCTTACGCCTCCTCACACTCGTCAGACAGCGAGGACGATGGGGTGGGAGCTGAGGAA
AAATGGGACCCGGCCAGGGGCGCCGTCCACAGCACCCCCAAAGGGATGAAGGGATCCAGAAGCTCGGCGTGTCCTCTGGGCTGGTGAGGG
GCAGCCACGGAGAGCCAGACGCGTCCCTCATGCCCAGGAGCTGCAAGGATCCCCCTGCGCTCCCTCAACTGCAACACCACCTTCGGTGAC
GGGCCTGACATGCTGCGCACAGACTTGGGCGAGTCCACCGCCTCGCTGGACAGCATCGTCAGGGCCCCTTCGTCCTCCTTTTCCACTGCG
TGCTCAACCAGGAGGTCCGGAAGCACCTGAAGGGCGTGCTCGGCGGGAGGAAGCTGCACCTGGAGGACTCCGCCACCACCAGGGCCACCC
TGCTGACGCTCCCTGCTGAGGACCGCATTCCTCCTGCTGCTGCTCATCAGCGCCACCTGGCTGCTGGGGCTGCTGGCTGTGAACCGCGAT
GCACTGAGCTTTCACTACCTCTTCGCCATCTTCAGCGGCTTACAGATCAACACAGTCACTTCTGTCCTATCTGCAAAGGTTTCCTGCCAA
AGAAAGCACCATTATTATGGGAAAAAAGGGATCGTGACTGGCGGTCGGCCTGGACCCCCAGGGCTACGGGAACCCCGACTTCTGCTGGCT
GTCGCTTCAAGACACCCTGATTTGGAGCTTTGCGGGGCCCATCGGAGCTGTTATAATCTTTCTGTGCACAGTGGTTGCCATCCTCCTCCA
CTACATCTACATGAGCACCTTTGCCTGGACCCTCGTGGAGAGCCTGCATGTCTACCGCATGCTGACCGAGGTGCGCAACATCGACACGGG
GCCCATGCGGTTCTACTACGTCGTGGGCTGGGGCATCCCGGCCATTGTCACAGAACGGGGAGGTCCTGCCTCTGAAGATTGTCACCTATG
CCGCTGTGTCCTTGTCACTGGCAGCCCTGCTGGTGGCCTTCGTCCTCCTGAGCCTGGTCCGCATGCTGCGCTCCAACCTGCACAGCATTC
ACAAGCACCTCGCCGTGGCGCTCTTCCTCTCTCAGCTGGTGTTCGTGATTGGGATCAACCAGACGGAAAACCCGCGTTGGTGGGACGGGA
GGGTGGTCTGCCCGGGGCTGCGAGCTCCTGTCCAGGAACCGGACACATGTCGCCTGCCAGTGCAGCCACACAGCCAGCTTTGCGGTGCTC
ATGGATATCTCCAGGCGTGAGGTTGCCTCACCGGCCCATCATTAATACCCCGATGGTGAGCACGCTGGTGTACAGCGAGGGGGCTCCGCT
CCCGAGACCCCTGGAGAGGCCCGTCCTGGTGGAGTTCGCCCTGCTGGAGGTGGAGGAGCGAACCAAGCCTGTCTGCGTGTTCTGGAACCA
CTCCCTGGCAAGGCCCCCTGCTGAGGCCGGCTGGCCGGAGGACCACCCCGCAGACCACGCGCCCGGGGCCTGGCACCGAGAGGGAGGCCC
CGATCAGCAGGCGGAGGCGACACCCTGATGACGCTGGCCAGTTCGCCGTCGCTCTGGTCATCATTTACCGCACCCTGGGGCAGCTCCTGC
CCGAGCGCTACGACCCCGACCGTCGCAGCCTCCGTTCTTGCTGTCGACATCTTTGACAAGTTCAACTTTACGGGAGCCAGGGTCCCGCGA
TTCGACACCATCCATGAAGAGTTCCCCAGGGAGCTGGAGTCCTCCGTCTCCTTCCCAGCCGACTTCTTCAGACCACCTGAAGAAAAAGGA
CGTCATCCACTCGGGCAGCGCCCTCCTGGCCCCAGCCACCAGGGCGGCGTGGGAGCAGATCCAGCGGAGCGAGGGCGGCACGGCACAGCT
GCTCCGGCGCCTCGAGGGCTACTTCAGCAACGTGGCACGCAACGTGCGGCGGACGTACCTGCGGCCCTTCGTCATCGTCACCGCCAACAT
GAAATGAGAAGCTGAGCCGCAATGAGACGCAGGTGGACGGCGCCAGGGCCCTGCAGCTGGTGAGGGCGCTGCGCAGTGCTACACAGCACA
CGGGCACGCTCTTTGGCAATGACGTGCGCACGGCCTACCAGCTGCTGGGCCACGTCCTTCAGCACGAGAGCTGGCAGCAGGGCTTCGACC
TGGCAGCCACGCAGGACGCCGACTTTCACGAGGAAATGCGGTCCGACACTGCAGCGGGGAGAAGGGCTGGCTGCCCCCAGAGCTCTTTAA
CTGTACCACCATCTCCTTCGTGGACCTCAGGGCCATGTGATCTACAATGGCTGTCCCAAAGCATTTGAGGCCGGCATCTGGTGGCCACAG
ACCAAGTTCGGGCAGCCGGCTGCGGTGCCATGCCCTAAGGGATCCGTTGGAGAATTACTACAAGCTCCTAGCCCAGGACACCTGTCTGCC
CTGCGACTGCTTCCCCCATGGCTCCCACAGCCGCACTTGCGACATGGCCACCGGGCAGTGTGCCTGCAAGCCCGGCGTCATCGGCCGCCA
GTGCAACCGCTGCGACAACCCGTTTGCCGAGGTCACCACGCTCGGCTGTGAAGACTCGACCTTCCGTGCCCCAGAGGCTGGTGGGGGAAC
CCCGTCTGTGGACCCTGCCACTGTGCCGTCAGCAAAGGCTTTGATCCCGACTGTAATAAGACCAACGGCCAGTGCCAATGCAAGCTGTGT
GGATGCCTGTCACCTGAACCCCTGCGAGAACATGGGGGCCTGCGTGCGCTCCCCCGGCTCCCCGCAGGGCTACGTGTGCGAGTGTGGGCC

>22311_22311_7_DEPDC5-CELSR1_DEPDC5_chr22_32275603_ENST00000535622_CELSR1_chr22_46792627_ENST00000262738_length(amino acids)=1240AA_BP=1206
MRTTKVYKLVIHKKGFGGSDDELVVNPKVFPHIKLGDIVEIAHPNDEYSPLLLQVKSLKEDLQKETISVDQTVTQVFRLRPYQDVYVNVV
DPKDVTLDLVELTFKDQYIGRGDMWRLKKSLVSTCAYITQKVEFAGIRAQAGELWVKNEKVMCGYISEDTRVVFRSTSAMVYIFIQMSCE
MWDFDIYGDLYFEKAVNGFLADLFTKWKEKNCSHEVTVVLFSRTFYDAKSVDEFPEINRASIRQDHKGRFYEDFYKVVVQNERREEWTSL
LVTIKKLFIQYPVLVRLEQAEGFPQGDNSTSAQGNYLEAINLSFNVFDKHYINRNFDRTGQMSVVITPGVGVFEVDRLLMILTKQRMIDN
GIGVDLVCMGEQPLHAVPLFKLHNRSAPRDSRLGDDYNIPHWINHSFYTSKSQLFCNSFTPRIKLAGKKPASEKAKNGRDTSLGSPKESE
NALPIQVDYDAYDAQVFRLPGPSRAQCLTTCRSVRERESHSRKSASSCDVSSSPSLPSRTLPTEEVRSQASDDSSLGKSANILMIPHPHL
HQYEVSSSLGYTSTRDVLENMMEPPQRDSSAPGRFHVGSAESMLHVRPGGYTPQRALINPFAPSRMPMKLTSNRRRWMHTFPVGMNPRTQ
NKDSLEDSVSTSPDPILTLSAPPVVPGFCCTVGVDWKSLTTPACLPLTTDYFPDRQGLQNDYTEGCYDLLPEADIDRRDEDGVQMTAQQV
FEEFICQRLMQGYQIIVQPKTQKPNPAVPPPLSSSPLYSRGLVSRNRPEEEDQYWLSMGRTFHKVTLKDKMITVTRYLPKYPYESAQIHY
TYSLCPSHSDSEFVSCWVEFSHERLEEYKWNYLDQYICSAGSEDFSLIESLKFWRTRFLLLPACVTATKRITEGEAHCDIYGDRPRADED
EWQLLDGFVRFVEGLNRIRRRHRSDRMMRKGTAMKGLQMTGPISTHSLESTAPPVGKKGTSALSALLEMEASQKCLGEQQAAVHGGKSSA
QSAESSSVAMTPTYMDSPRKVSVDQTATPMLDGTSLGICTGQSMDRGNSQTFGNSQNIGEQGYSSTNSSDSSSQQLVASSLTSSSTLTEI
LEAMKHPSTGVQLLSEQKGLSPYCFISAEVVHWLVNHVEGIQTQAMAIDIMQKMLEEQLITHASGEAWRTFIYGFYFYKIVTDKEPDRAE

--------------------------------------------------------------
>22311_22311_8_DEPDC5-CELSR1_DEPDC5_chr22_32275603_ENST00000539165_CELSR1_chr22_46792627_ENST00000262738_length(transcript)=6551nt_BP=879nt
AAGAGGCAGCTGAAGCTGGATGGAGGGTGATGATGAGATGAAAAGGAAGGGATGAAGAACACGGCAGGGTGCCTACGGTGCCTGGGAGAA
CAGCAGGCAGCTGTGCATGGTGGGAAGAGCTCCGCCCAGTCAGCCGAGAGCAGCAGCGTTGCCATGACTCCCACCTACATGGACAGCCCA
CGAAAGGTATCTGTGGACCAAACAGCCACTCCTATGTTGGACGGCACCAGTTTGGGCATATGCACAGGCCAATCCATGGACAGAGGCAAC
AGCCAGACCTTTGGGAACTCCCAGAACATAGGAGAACAGGGCTACTCCTCCACAAACTCCAGTGACAGCAGGAAGTGGAGACTGTTCCTA
ATATTCGTGCTCTTGACTGCATACGTGCCATCTTGCTTTGCTGACCTGACACCCTGTGTTACAGCTCTCAGCAGCTGGTGGCAAGCTCCT
TGACCTCATCCTCTACCCTGACAGAGATCCTGGAAGCCATGAAGCACCCCTCGACAGGAGTCCAGCTGCTCTCTGAACAGAAGGGCCTCT
CACCGTACTGCTTCATCAGCGCGGAGGTGGTACACTGGTTGGTGAACCACGTGGAGGGGATCCAGACACAGGCGATGGCCATTGACATCA
TGCAGAAAATGCTGGAAGAGCAGCTCATCACACATGCATCTGGCGAAGCCTGGCGGACCTTCATCTACGGCTTCTATTTCTACAAGATAG
TAACGGACAAAGAGCCCGACCGAGCAGAAGAGCTCGTGCACTCTGAGATTCCTGCCTTTCTCCTGCCCTGGCTGCCTAGCCGGCCAGCCT
CCTATGCAAGTAGGCACAGCTCCTTTAGCCGAAGTTTTGGAGGACGGAGCCAGGCGGCAGCACTTTTAGGAAACCGTGAGGCAAGCCCGT
CACCCCACACAGGCTGCGGCATCACCCTCAGACCTTGGAGCCCAAGGGGCCACTGCCCTTGAAGTGGAGTGGGCCCAGAGTGTGGCGGTC
CCCATGGTGGCAGCCCCCCGACTGATCATCCAGACACAAAGGTCTTGGTTCTCCCAGGAGCTCAGGGCCTGTCAGACCTGGTGACAAGTG
CCAAAGGCCACAGGCATGAGGGAGGCGTGGACCACTGGGCCAGCACCGCTGAGTCCTAAGACTGCAGTCAAAGCCAGAACTGAGAGGGGA
CCCCAGACTGGGCCCAGAGGCTGGCCAGAGTTCAGGAACGCCGGGCACAGACCAAAGACCGCGGTCCAGCCCCGCCCAGGCGGGCATCTC
ATGGCAGTGCGGACCCGTGGCTGGCAGCCCGGGCAGTCCTTTGCAAAGGCACCCCTTGTCTTAAAATCACTTCGCTATGTGGGAAAGGTG
GAGATACTTTTATATATTTGTATGGGACTCTGAGGAGGTGCAACCTGTATATATATTGCATTCGTGCTGACTTTGTTATCCCGAGAGATC
CATGCAATGATCTCTTGCTGTCTTCTCTGTCAAGATTGCACAGTTGTACTTGAATCTGGCATGTGTTGACGAAACTGGTGCCCCAGCAGA
TCAAAGGTGGGAAATACGTCAGCAGTGGGGCTAAAACCAAGCGGCTAGAAGCCCTACAGCTGCCTTCGGCCAGGAAGTGAGGATGGTGTG
GGCCCTCCCCGCCGGCCCCCTGGGTCCCCAGTGTTCGCTGTGTGTGCGTTTGTCCTCTGCTGCCATCTGCCCCGGCTGTGTGAATTCAAG
ACAGGGCAGTGCAGCACTAGGCAGGTGTGAGGAGCCCTGCTGAGGTCACTGTGGGGCACGGTTGCCACACGGCTGTCATTTTTCACCTGG
TCATTCTGTGACCACCACCCCCTCCCCTCACCGCCTCCCAGGTGGCCCGGGAGCTGCAGGTGGGGATGGCTTTGTCCTTTGCTCCTGCTC
CCCGTGGGACCTGGGACCTTAAAGCGTTGCAGGTTCCTGATTTGGACAGAGGTGTGGGGCCTTCCAGGCCGTTACATACCTCCTGCCAAT
TCTCTAACTCTCTGAGACTGCGAGGATCTCCAGGCAGGGTTCTCCCCTCTGGAGTCTGACCAATTACTTCATTTTGCTTCAAATGGCCAA
TTGTGCAGAGGGACAAAGCCACAGCCACACTCTTCAACGGTTACCAAACTGTTTTTGGAAATTCACACCAAGGTCGGGCCCACTGCAGGC
AGCTGGCACAGCGTGGCCCGAGGGGCTGTGGAACGGGTCCCGGAACTGTCAGACATGTTTGATTTTAGCGTTTCCTTTGTTCTTCAAATC
AGGTGCCCAAATAAGTGATCAGCACAGCTGCTTCCAAATAGGAGAAACCATAAAATAGGATGAAAATCAAGTAAAATGCAAAGATGTCCA
CACTGTTTTAAACTTGACCCTGATGAAAATGTGAGCACTGTTAGCAGATGCCTATGGGAGAGGAAAAGCGTATCTGAAAATGGTCCAGGA
CAGGAGGATGAAATGAGATCCCAGAGTCCTCACACCTGAATGAATTATACATGTGCCTTACCAGGTGAGTGGTCTTTCGAAGATAAAAAA
CTCTAGTCCCTTTAAACGTTTGCCCCTGGCGTTTCCTAAGTACGAAAAGGTTTTTAAGTCTTCGAACAGTCTCCTTTCATGACTTTAACA
GGATTCTGCCCCCTGAGGTGTAATTTTTTTGTTCTATTTTTTTCCACGTACTCCACAGCCAACATCACGAGGTGTAATTTTTAATTTGAT
CAGAACTGTTACCAAAAAACAACTGTCAGTTTTATTGAGATGGGAAAAATGTAAACCTATTTTTATTACTTAAGACTTTATGGGAGAGAT
TAGACACTGGAGGTTTTTAACAGAACGTGTATTTATTAATGTTCAAAACACTGGAATTACAAATGAGAAGAGTCTACAATAAATTAAGAT
TTTTGAATTTGTACTTCTGCGGTGCTGGTTTTTCTCCACAAACACCCCCGCCCCTCCCCATGCCCAGGGTGGCCGTGGAAGGGACGGTTT
ACGGACGTGCAGCTGAGCTGTCCGTGTCCCATGCTCCCTCAGCCAGTGGAACGTGCCGGAACTTTTTGTCCATTCCCTAGTAGGCCTGCC
ACAGCCTAGATGGGCAGTTTTTGTCTTTCACCAAATTTGAGGACTTTTTTTTTTTGCCATTATTTCTTCAGTTTTCTTTTCTTGCACTGA
TCTTTCTCCTCTCCTTCTGTGACTCCAGTGACTCAGACGTTAGACCTCTTGATGTTTTCCCACTGGTCCCTGAGGCTCTGTTCGCATCTT
GAAAAATAAAGTCACCTACCCGCCGCCGCTGACGCTGACGGAGCAGACGCTGAAGGGCCGGCTCCGGGAGAAGCTGGCCGACTGTGAGCA
GAGCCCCACATCCTCGCGCACGTCTTCCCTGGGCTCTGGCGGCCCCGACTGCGCCATCACAGTCAAGAGCCCTGGGAGGGAGCCGGGGCG
TGACCACCTCAACGGGGTGGCCATGAATGTGCGCACTGGGAGCGCCCAGGCCGATGGCTCCGACTCTGAGGGACGCTGTGGCCAACCACG
TTCCGGCCGGCTGGCCCGACCAGAGCCTGGCTGAGAGTGACAGTGAGGACCCCAGCGGCAAGCCCCGCCTGAAGGTGGAGACCAAGGTCA
GCGTGGAGCTGCACCGCGAGGAGCAGGGCAGTCACCGTGGAGAGTACCCCCCGGACCAGGAGAGCGGGGGCGCAGCCAGGCTTGCTAGCA
GCCAGCCCCCAGAGCAGAGGAAAGGCCACGATTCCGACTCAGATAGCGAGCTGTCCCTGGATGAGCAGAGCAGCTCTTACGCCTCCTCAC
ACTCGTCAGACAGCGAGGACGATGGGGTGGGAGCTGAGGAAAAATGGGACCCGGCCAGGGGCGCCGTCCACAGCACCCCCAAAGGGATGA
AGGGATCCAGAAGCTCGGCGTGTCCTCTGGGCTGGTGAGGGGCAGCCACGGAGAGCCAGACGCGTCCCTCATGCCCAGGAGCTGCAAGGA
TCCCCCTGCGCTCCCTCAACTGCAACACCACCTTCGGTGACGGGCCTGACATGCTGCGCACAGACTTGGGCGAGTCCACCGCCTCGCTGG
ACAGCATCGTCAGGGCCCCTTCGTCCTCCTTTTCCACTGCGTGCTCAACCAGGAGGTCCGGAAGCACCTGAAGGGCGTGCTCGGCGGGAG
GAAGCTGCACCTGGAGGACTCCGCCACCACCAGGGCCACCCTGCTGACGCTCCCTGCTGAGGACCGCATTCCTCCTGCTGCTGCTCATCA
GCGCCACCTGGCTGCTGGGGCTGCTGGCTGTGAACCGCGATGCACTGAGCTTTCACTACCTCTTCGCCATCTTCAGCGGCTTACAGATCA
ACACAGTCACTTCTGTCCTATCTGCAAAGGTTTCCTGCCAAAGAAAGCACCATTATTATGGGAAAAAAGGGATCGTGACTGGCGGTCGGC
CTGGACCCCCAGGGCTACGGGAACCCCGACTTCTGCTGGCTGTCGCTTCAAGACACCCTGATTTGGAGCTTTGCGGGGCCCATCGGAGCT
GTTATAATCTTTCTGTGCACAGTGGTTGCCATCCTCCTCCACTACATCTACATGAGCACCTTTGCCTGGACCCTCGTGGAGAGCCTGCAT
GTCTACCGCATGCTGACCGAGGTGCGCAACATCGACACGGGGCCCATGCGGTTCTACTACGTCGTGGGCTGGGGCATCCCGGCCATTGTC
ACAGAACGGGGAGGTCCTGCCTCTGAAGATTGTCACCTATGCCGCTGTGTCCTTGTCACTGGCAGCCCTGCTGGTGGCCTTCGTCCTCCT
GAGCCTGGTCCGCATGCTGCGCTCCAACCTGCACAGCATTCACAAGCACCTCGCCGTGGCGCTCTTCCTCTCTCAGCTGGTGTTCGTGAT
TGGGATCAACCAGACGGAAAACCCGCGTTGGTGGGACGGGAGGGTGGTCTGCCCGGGGCTGCGAGCTCCTGTCCAGGAACCGGACACATG
TCGCCTGCCAGTGCAGCCACACAGCCAGCTTTGCGGTGCTCATGGATATCTCCAGGCGTGAGGTTGCCTCACCGGCCCATCATTAATACC
CCGATGGTGAGCACGCTGGTGTACAGCGAGGGGGCTCCGCTCCCGAGACCCCTGGAGAGGCCCGTCCTGGTGGAGTTCGCCCTGCTGGAG
GTGGAGGAGCGAACCAAGCCTGTCTGCGTGTTCTGGAACCACTCCCTGGCAAGGCCCCCTGCTGAGGCCGGCTGGCCGGAGGACCACCCC
GCAGACCACGCGCCCGGGGCCTGGCACCGAGAGGGAGGCCCCGATCAGCAGGCGGAGGCGACACCCTGATGACGCTGGCCAGTTCGCCGT
CGCTCTGGTCATCATTTACCGCACCCTGGGGCAGCTCCTGCCCGAGCGCTACGACCCCGACCGTCGCAGCCTCCGTTCTTGCTGTCGACA
TCTTTGACAAGTTCAACTTTACGGGAGCCAGGGTCCCGCGATTCGACACCATCCATGAAGAGTTCCCCAGGGAGCTGGAGTCCTCCGTCT
CCTTCCCAGCCGACTTCTTCAGACCACCTGAAGAAAAAGGACGTCATCCACTCGGGCAGCGCCCTCCTGGCCCCAGCCACCAGGGCGGCG
TGGGAGCAGATCCAGCGGAGCGAGGGCGGCACGGCACAGCTGCTCCGGCGCCTCGAGGGCTACTTCAGCAACGTGGCACGCAACGTGCGG
CGGACGTACCTGCGGCCCTTCGTCATCGTCACCGCCAACATGAAATGAGAAGCTGAGCCGCAATGAGACGCAGGTGGACGGCGCCAGGGC
CCTGCAGCTGGTGAGGGCGCTGCGCAGTGCTACACAGCACACGGGCACGCTCTTTGGCAATGACGTGCGCACGGCCTACCAGCTGCTGGG
CCACGTCCTTCAGCACGAGAGCTGGCAGCAGGGCTTCGACCTGGCAGCCACGCAGGACGCCGACTTTCACGAGGAAATGCGGTCCGACAC
TGCAGCGGGGAGAAGGGCTGGCTGCCCCCAGAGCTCTTTAACTGTACCACCATCTCCTTCGTGGACCTCAGGGCCATGTGATCTACAATG
GCTGTCCCAAAGCATTTGAGGCCGGCATCTGGTGGCCACAGACCAAGTTCGGGCAGCCGGCTGCGGTGCCATGCCCTAAGGGATCCGTTG
GAGAATTACTACAAGCTCCTAGCCCAGGACACCTGTCTGCCCTGCGACTGCTTCCCCCATGGCTCCCACAGCCGCACTTGCGACATGGCC
ACCGGGCAGTGTGCCTGCAAGCCCGGCGTCATCGGCCGCCAGTGCAACCGCTGCGACAACCCGTTTGCCGAGGTCACCACGCTCGGCTGT
GAAGACTCGACCTTCCGTGCCCCAGAGGCTGGTGGGGGAACCCCGTCTGTGGACCCTGCCACTGTGCCGTCAGCAAAGGCTTTGATCCCG
ACTGTAATAAGACCAACGGCCAGTGCCAATGCAAGCTGTGTGGATGCCTGTCACCTGAACCCCTGCGAGAACATGGGGGCCTGCGTGCGC

>22311_22311_8_DEPDC5-CELSR1_DEPDC5_chr22_32275603_ENST00000539165_CELSR1_chr22_46792627_ENST00000262738_length(amino acids)=296AA_BP=
MAVGLDPQGYGNPDFCWLSLQDTLIWSFAGPIGAVIIFLCTVVAILLHYIYMSTFAWTLVESLHVYRMLTEVRNIDTGPMRFYYVVGWGI
PAIVTERGGPASEDCHLCRCVLVTGSPAGGLRPPEPGPHAALQPAQHSQAPRRGALPLSAGVRDWDQPDGKPALVGREGGLPGAASSCPG
TGHMSPASAATQPALRCSWISPGVRLPHRPIINTPMVSTLVYSEGAPLPRPLERPVLVEFALLEVEERTKPVCVFWNHSLARPPAEAGWP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for DEPDC5-CELSR1


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ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DEPDC5-CELSR1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DEPDC5-CELSR1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource