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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ABCB9-EIF2B1 (FusionGDB2 ID:224)

Fusion Gene Summary for ABCB9-EIF2B1

check button Fusion gene summary
Fusion gene informationFusion gene name: ABCB9-EIF2B1
Fusion gene ID: 224
HgeneTgene
Gene symbol

ABCB9

EIF2B1

Gene ID

23457

1967

Gene nameATP binding cassette subfamily B member 9eukaryotic translation initiation factor 2B subunit alpha
SynonymsEST122234|TAPLEIF2B|EIF2BA
Cytomap

12q24.31

12q24.31

Type of geneprotein-codingprotein-coding
DescriptionATP-binding cassette sub-family B member 9ABC transporter 9 proteinATP-binding cassette, sub-family B (MDR/TAP), member 9TAP-like proteintranslation initiation factor eIF-2B subunit alphaeIF-2B GDP-GTP exchange factor subunit alphaeukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
Modification date2020031320200327
UniProtAcc

Q9NP78

Q14232

Ensembl transtripts involved in fusion geneENST00000280560, ENST00000344275, 
ENST00000392439, ENST00000442028, 
ENST00000442833, ENST00000540285, 
ENST00000542678, ENST00000541983, 
ENST00000346530, 		ENST00000537073, 
ENST00000543940, ENST00000424014, 
ENST00000539951, 
Fusion gene scores* DoF score4 X 4 X 4=643 X 4 X 3=36
# samples 44
** MAII scorelog2(4/64*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: ABCB9 [Title/Abstract] AND EIF2B1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointABCB9(123428938)-EIF2B1(124107308), # samples:3
Anticipated loss of major functional domain due to fusion event.ABCB9-EIF2B1 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
ABCB9-EIF2B1 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
ABCB9-EIF2B1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneABCB9

GO:0002474

antigen processing and presentation of peptide antigen via MHC class I

17977821

HgeneABCB9

GO:0015833

peptide transport

17977821|18434309|22641697

TgeneEIF2B1

GO:0006413

translational initiation

16289705

TgeneEIF2B1

GO:0050852

T cell receptor signaling pathway

8626696


check buttonFusion gene breakpoints across ABCB9 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EIF2B1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A7-A13D-01AABCB9chr12

123428938

-EIF2B1chr12

124107308

-


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Fusion Gene ORF analysis for ABCB9-EIF2B1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000280560ENST00000537073ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
5CDS-intronENST00000280560ENST00000543940ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
5CDS-intronENST00000344275ENST00000537073ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
5CDS-intronENST00000344275ENST00000543940ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
5CDS-intronENST00000392439ENST00000537073ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
5CDS-intronENST00000392439ENST00000543940ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
5CDS-intronENST00000442028ENST00000537073ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
5CDS-intronENST00000442028ENST00000543940ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
5CDS-intronENST00000442833ENST00000537073ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
5CDS-intronENST00000442833ENST00000543940ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
5CDS-intronENST00000540285ENST00000537073ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
5CDS-intronENST00000540285ENST00000543940ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
5CDS-intronENST00000542678ENST00000537073ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
5CDS-intronENST00000542678ENST00000543940ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
5UTR-3CDSENST00000541983ENST00000424014ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
5UTR-3CDSENST00000541983ENST00000539951ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
5UTR-intronENST00000541983ENST00000537073ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
5UTR-intronENST00000541983ENST00000543940ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
Frame-shiftENST00000392439ENST00000424014ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
Frame-shiftENST00000392439ENST00000539951ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
Frame-shiftENST00000442028ENST00000424014ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
Frame-shiftENST00000442028ENST00000539951ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
Frame-shiftENST00000542678ENST00000424014ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
Frame-shiftENST00000542678ENST00000539951ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
In-frameENST00000280560ENST00000424014ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
In-frameENST00000280560ENST00000539951ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
In-frameENST00000344275ENST00000424014ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
In-frameENST00000344275ENST00000539951ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
In-frameENST00000442833ENST00000424014ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
In-frameENST00000442833ENST00000539951ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
In-frameENST00000540285ENST00000424014ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
In-frameENST00000540285ENST00000539951ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
intron-3CDSENST00000346530ENST00000424014ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
intron-3CDSENST00000346530ENST00000539951ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
intron-intronENST00000346530ENST00000537073ABCB9chr12

123428938

-EIF2B1chr12

124107308

-
intron-intronENST00000346530ENST00000543940ABCB9chr12

123428938

-EIF2B1chr12

124107308

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000344275ABCB9chr12123428938-ENST00000424014EIF2B1chr12124107308-328216412251931568
ENST00000344275ABCB9chr12123428938-ENST00000539951EIF2B1chr12124107308-195016412251931568
ENST00000442833ABCB9chr12123428938-ENST00000424014EIF2B1chr12124107308-328216412251931568
ENST00000442833ABCB9chr12123428938-ENST00000539951EIF2B1chr12124107308-195016412251931568
ENST00000280560ABCB9chr12123428938-ENST00000424014EIF2B1chr12124107308-331816772611967568
ENST00000280560ABCB9chr12123428938-ENST00000539951EIF2B1chr12124107308-198616772611967568
ENST00000540285ABCB9chr12123428938-ENST00000424014EIF2B1chr12124107308-332216812651971568
ENST00000540285ABCB9chr12123428938-ENST00000539951EIF2B1chr12124107308-199016812651971568

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000344275ENST00000424014ABCB9chr12123428938-EIF2B1chr12124107308-0.0037205630.9962794
ENST00000344275ENST00000539951ABCB9chr12123428938-EIF2B1chr12124107308-0.0169448820.9830551
ENST00000442833ENST00000424014ABCB9chr12123428938-EIF2B1chr12124107308-0.0037205630.9962794
ENST00000442833ENST00000539951ABCB9chr12123428938-EIF2B1chr12124107308-0.0169448820.9830551
ENST00000280560ENST00000424014ABCB9chr12123428938-EIF2B1chr12124107308-0.00378640.9962136
ENST00000280560ENST00000539951ABCB9chr12123428938-EIF2B1chr12124107308-0.0168007560.9831993
ENST00000540285ENST00000424014ABCB9chr12123428938-EIF2B1chr12124107308-0.0037913170.99620867
ENST00000540285ENST00000539951ABCB9chr12123428938-EIF2B1chr12124107308-0.0168466290.9831534

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Fusion Genomic Features for ABCB9-EIF2B1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ABCB9-EIF2B1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:123428938/chr12:124107308)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ABCB9

Q9NP78

EIF2B1

Q14232

FUNCTION: ATP-dependent low-affinity peptide transporter which translocates a broad spectrum of peptides from the cytosol to the lysosomal lumen. Displays a broad peptide length specificity from 6-mer up to at least 59-mer peptides with an optimum of 23-mers. Favors positively charged, aromatic or hydrophobic residues in the N- and C-terminal positions whereas negatively charged residues as well as asparagine and methionine are not favored. {ECO:0000269|PubMed:15863492, ECO:0000269|PubMed:17977821, ECO:0000269|PubMed:18434309}.FUNCTION: Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABCB9chr12:123428938chr12:124107308ENST00000280560-712384_389460767.0Compositional biasNote=Poly-Glu
HgeneABCB9chr12:123428938chr12:124107308ENST00000344275-712384_389460682.0Compositional biasNote=Poly-Glu
HgeneABCB9chr12:123428938chr12:124107308ENST00000392439-712384_389460767.0Compositional biasNote=Poly-Glu
HgeneABCB9chr12:123428938chr12:124107308ENST00000442833-712384_389460684.0Compositional biasNote=Poly-Glu
HgeneABCB9chr12:123428938chr12:124107308ENST00000540285-711384_389460704.0Compositional biasNote=Poly-Glu
HgeneABCB9chr12:123428938chr12:124107308ENST00000542678-712384_389460767.0Compositional biasNote=Poly-Glu
HgeneABCB9chr12:123428938chr12:124107308ENST00000280560-712116_136460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000280560-712185_205460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000280560-712225_245460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000280560-712319_339460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000280560-712416_436460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000280560-71247_67460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000280560-7127_27460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000280560-71284_104460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000344275-712116_136460682.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000344275-712185_205460682.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000344275-712225_245460682.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000344275-712319_339460682.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000344275-712416_436460682.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000344275-71247_67460682.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000344275-7127_27460682.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000344275-71284_104460682.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000392439-712116_136460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000392439-712185_205460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000392439-712225_245460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000392439-712319_339460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000392439-712416_436460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000392439-71247_67460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000392439-7127_27460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000392439-71284_104460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000442833-712116_136460684.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000442833-712185_205460684.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000442833-712225_245460684.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000442833-712319_339460684.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000442833-712416_436460684.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000442833-71247_67460684.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000442833-7127_27460684.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000442833-71284_104460684.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000540285-711116_136460704.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000540285-711185_205460704.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000540285-711225_245460704.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000540285-711319_339460704.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000540285-711416_436460704.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000540285-71147_67460704.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000540285-7117_27460704.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000540285-71184_104460704.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000542678-712116_136460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000542678-712185_205460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000542678-712225_245460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000542678-712319_339460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000542678-712416_436460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000542678-71247_67460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000542678-7127_27460767.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000542678-71284_104460767.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABCB9chr12:123428938chr12:124107308ENST00000346530-111384_3890724.0Compositional biasNote=Poly-Glu
HgeneABCB9chr12:123428938chr12:124107308ENST00000280560-712188_471460767.0DomainABC transmembrane type-1
HgeneABCB9chr12:123428938chr12:124107308ENST00000280560-712504_740460767.0DomainABC transporter
HgeneABCB9chr12:123428938chr12:124107308ENST00000344275-712188_471460682.0DomainABC transmembrane type-1
HgeneABCB9chr12:123428938chr12:124107308ENST00000344275-712504_740460682.0DomainABC transporter
HgeneABCB9chr12:123428938chr12:124107308ENST00000346530-111188_4710724.0DomainABC transmembrane type-1
HgeneABCB9chr12:123428938chr12:124107308ENST00000346530-111504_7400724.0DomainABC transporter
HgeneABCB9chr12:123428938chr12:124107308ENST00000392439-712188_471460767.0DomainABC transmembrane type-1
HgeneABCB9chr12:123428938chr12:124107308ENST00000392439-712504_740460767.0DomainABC transporter
HgeneABCB9chr12:123428938chr12:124107308ENST00000442833-712188_471460684.0DomainABC transmembrane type-1
HgeneABCB9chr12:123428938chr12:124107308ENST00000442833-712504_740460684.0DomainABC transporter
HgeneABCB9chr12:123428938chr12:124107308ENST00000540285-711188_471460704.0DomainABC transmembrane type-1
HgeneABCB9chr12:123428938chr12:124107308ENST00000540285-711504_740460704.0DomainABC transporter
HgeneABCB9chr12:123428938chr12:124107308ENST00000542678-712188_471460767.0DomainABC transmembrane type-1
HgeneABCB9chr12:123428938chr12:124107308ENST00000542678-712504_740460767.0DomainABC transporter
HgeneABCB9chr12:123428938chr12:124107308ENST00000280560-712539_546460767.0Nucleotide bindingATP
HgeneABCB9chr12:123428938chr12:124107308ENST00000344275-712539_546460682.0Nucleotide bindingATP
HgeneABCB9chr12:123428938chr12:124107308ENST00000346530-111539_5460724.0Nucleotide bindingATP
HgeneABCB9chr12:123428938chr12:124107308ENST00000392439-712539_546460767.0Nucleotide bindingATP
HgeneABCB9chr12:123428938chr12:124107308ENST00000442833-712539_546460684.0Nucleotide bindingATP
HgeneABCB9chr12:123428938chr12:124107308ENST00000540285-711539_546460704.0Nucleotide bindingATP
HgeneABCB9chr12:123428938chr12:124107308ENST00000542678-712539_546460767.0Nucleotide bindingATP
HgeneABCB9chr12:123428938chr12:124107308ENST00000346530-111116_1360724.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000346530-111185_2050724.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000346530-111225_2450724.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000346530-111319_3390724.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000346530-111416_4360724.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000346530-11147_670724.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000346530-1117_270724.0TransmembraneHelical
HgeneABCB9chr12:123428938chr12:124107308ENST00000346530-11184_1040724.0TransmembraneHelical


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Fusion Gene Sequence for ABCB9-EIF2B1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>224_224_1_ABCB9-EIF2B1_ABCB9_chr12_123428938_ENST00000280560_EIF2B1_chr12_124107308_ENST00000424014_length(transcript)=3318nt_BP=1677nt
CGCCCCGTCCATCAGCCTGTCTCAACGCACGCCAGTCTCAGCTCCGACCTTGCAGCGGCGCAGCGCGGGTGGGAGGCGGGGAGGAGCAGC
GGGAAGAGCGGAGCGAGGACCGCGTCCGGCGCAGTCTTCAATGAGCAGCGCGGAAACTGCACCCCAGACCCGAGCCTGCTGCGCGCCCCC
TCCCAGAGCTCACCTGGTGCCAGGTAACAGGCCTGGCCTCGCCCTGTGGATGATGATGGCCTTGCCCCCGTGAGCTACAACCTGGCCTTC
AGCACCCGCCCACCTCCAACCAGCAGGATGCGGCTGTGGAAGGCGGTGGTGGTGACTTTGGCCTTCATGAGTGTGGACATCTGCGTGACC
ACGGCCATCTATGTCTTCAGCCACCTGGACCGCAGCCTCCTGGAGGACATCCGCCACTTCAACATCTTTGACTCGGTGCTGGATCTCTGG
GCAGCCTGCCTGTACCGCAGCTGCCTGCTGCTGGGAGCCACCATTGGTGTGGCCAAGAACAGTGCGCTGGGGCCCCGGCGGCTGCGGGCC
TCGTGGCTGGTCATCACCCTCGTGTGCCTCTTCGTGGGCATCTATGCCATGGTGAAGCTGCTGCTCTTCTCAGAGGTGCGCAGGCCCATC
CGGGACCCCTGGTTTTGGGCCCTGTTCGTGTGGACGTACATTTCACTCGGCGCATCCTTCCTGCTCTGGTGGCTGCTGTCCACCGTGCGG
CCAGGCACCCAGGCCCTGGAGCCAGGGGCGGCCACCGAGGCTGAGGGCTTCCCTGGGAGCGGCCGGCCACCGCCCGAGCAGGCGTCTGGG
GCCACGCTGCAGAAGCTGCTCTCCTACACCAAGCCCGACGTGGCCTTCCTCGTGGCCGCCTCCTTCTTCCTCATCGTGGCAGCTCTGGGA
GAGACCTTCCTGCCCTACTACACGGGCCGCGCCATTGATGGCATCGTCATCCAGAAAAGCATGGATCAGTTCAGCACGGCTGTCGTCATC
GTGTGCCTGCTGGCCATTGGCAGCTCATTTGCCGCAGGTATTCGGGGCGGCATTTTTACCCTCATATTTGCCAGACTGAACATTCGCCTT
CGAAACTGTCTCTTCCGCTCACTGGTGTCCCAGGAGACAAGCTTCTTTGATGAGAACCGCACAGGGGACCTCATCTCCCGCCTGACCTCG
GACACCACCATGGTCAGCGACCTGGTCTCCCAGAACATCAATGTCTTCCTGCGGAACACAGTCAAGGTCACGGGCGTGGTGGTCTTCATG
TTCAGCCTCTCATGGCAGCTCTCCTTGGTCACCTTCATGGGCTTCCCCATCATCATGATGGTGTCCAACATCTACGGCAAGTACTACAAG
AGGCTCTCCAAAGAGGTCCAGAATGCCCTGGCCAGAGCGAGCAACACGGCGGAGGAGACCATCAGTGCCATGAAGACTGTCCGGAGCTTC
GCCAATGAGGAGGAGGAGGCAGAGGTGTACCTGCGGAAGCTGCAGCAGGTGTACAAGCTGAACAGGAAGGAGGCAGCTGCCTACATGTAC
TACGTCTGGGGCAGCGGGCTCACACTGCTGGTGGTCCAGGTCAGCATCCTCTACTACGGGGGCCACCTTGTCATCTCAGGCCAGATGACC
AGCGGCAACCTCATCGCCTTCATCATCTACGAGTTTGTCCTGGGAGATTGTATGGAGATTGGAACCAACCAGATGGCTGTGTGTGCCAAA
GCACAGAACAAACCTTTCTATGTGGTTGCAGAAAGTTTCAAGTTTGTCCGGCTCTTTCCACTAAACCAGCAAGACGTCCCAGATAAGTTT
AAGTATAAGGCAGACACTCTCAAGGTCGCGCAGACTGGACAAGACCTCAAAGAGGAGCATCCGTGGGTCGACTACACTGCCCCTTCCTTA
ATCACTCTGCTGTTTACAGACCTGGGCGTGCTGACACCCTCAGCAGTCAGCGATGAGCTCATCAAGCTCTATCTGTAACCTGTGAGCCCT
TTCCTGCCAAGGTGCAGCTTACGTAGTTGAGGCAGGGTGAGTAGCTGCTTGACACCCCAGTGAGTCAGGCCAAAACTGAGATGTGTTTAA
TGAAGATTTATGGAGTAAGGACTTAAAATCATACATCTTGGAGAACCTTTCTTACTCATTTCAGTCCCATCTAAAAATGTGTCAGCTATT
CTAAATCCCAACTTAAATTGTTCTTACGGTTTCTAGAAACTTTCCTTTTCAGTTTCCAGAAATACAAGTTAGATAATTGGCTACTTAACT
GATGAAAGATGAGCCCAAGTCCACCTGTCTTCATCCTCCCCTGCACTCCAGACTGATCTGCCTAAAGCACGCGAGATGCAGGCGAAAAGC
AGCCACACCCCTCTGCCACAAATGACCAACAGCTGGTCAGGACGTTACACGCGGTGCCTTGTAAGAGGCAAGAAACACTTGCTGAATCTG
CATCTGGCTTCCAGTGGTAAGCACATTCCTCAGCAGGATCAAGCCAAACAGTAAAAACTACCAAGAGAACACGAGGAAGGCAGAAACGAT
GTTTAGCAACAGTATTCTGCATGGTTCACTGCTTAAGAAAATGCCTTCTGGAATATTTGTAAACTGAAATTCTGTATGTGTAAGAGATGT
TTAAATATGTTTGGGTCCTAAACAGCTTTTTAAAATTATACTTGGGAATAAATTCAGCATCTTTTCAAATAAACTCTATGAAAGACGCTG
ATGTGGTGTTGCATCAATACTGCAAGCTGACCAGGCCATCTAGGGGAAAACACTGTCCAGCTACATTTACACACTTAAGACCCAGGCAAT
CAGGACACCATTTATTCAACAGGAGGCATAAAAACTATAATTCTCTTTCCCGGAATATGACTTAATCCCTCTGTTTTTCAGCTATTCACC
AATAAAACAATACTGTGACTATTAACACAGAAAAACCCCAGCACATTAGCCACCCCTGCAGGACATCAAAGGATAACTGAAGCCCAGGGC
CAAGCACATTCAGGAGGTCAAATGCCTGAAGATACTGAGGAATGGTTTTGAAAATCAGAAGTCAAGAAGACTTCTGTATCTTTATGTTTA
AAAATAACTATAAAATAGCCTCAGAAAAAAGAGCTTATATATATATATATATATATATATATATATATATATATATATATATAATATGTA
CATATGTCTATATGTGACCCATCATGATAAATACTGACATCTATTATTTACACTCAAATAATTTTACATTTTCTTCTGTTAGACTACTCC

>224_224_1_ABCB9-EIF2B1_ABCB9_chr12_123428938_ENST00000280560_EIF2B1_chr12_124107308_ENST00000424014_length(amino acids)=568AA_BP=472
MAFSTRPPPTSRMRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCLLLGATIGVAKNSALGPRR
LRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALFVWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQ
ASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLN
IRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGK
YYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTLLVVQVSILYYGGHLVISG
QMTSGNLIAFIIYEFVLGDCMEIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQDLKEEHPWVDYTA

--------------------------------------------------------------
>224_224_2_ABCB9-EIF2B1_ABCB9_chr12_123428938_ENST00000280560_EIF2B1_chr12_124107308_ENST00000539951_length(transcript)=1986nt_BP=1677nt
CGCCCCGTCCATCAGCCTGTCTCAACGCACGCCAGTCTCAGCTCCGACCTTGCAGCGGCGCAGCGCGGGTGGGAGGCGGGGAGGAGCAGC
GGGAAGAGCGGAGCGAGGACCGCGTCCGGCGCAGTCTTCAATGAGCAGCGCGGAAACTGCACCCCAGACCCGAGCCTGCTGCGCGCCCCC
TCCCAGAGCTCACCTGGTGCCAGGTAACAGGCCTGGCCTCGCCCTGTGGATGATGATGGCCTTGCCCCCGTGAGCTACAACCTGGCCTTC
AGCACCCGCCCACCTCCAACCAGCAGGATGCGGCTGTGGAAGGCGGTGGTGGTGACTTTGGCCTTCATGAGTGTGGACATCTGCGTGACC
ACGGCCATCTATGTCTTCAGCCACCTGGACCGCAGCCTCCTGGAGGACATCCGCCACTTCAACATCTTTGACTCGGTGCTGGATCTCTGG
GCAGCCTGCCTGTACCGCAGCTGCCTGCTGCTGGGAGCCACCATTGGTGTGGCCAAGAACAGTGCGCTGGGGCCCCGGCGGCTGCGGGCC
TCGTGGCTGGTCATCACCCTCGTGTGCCTCTTCGTGGGCATCTATGCCATGGTGAAGCTGCTGCTCTTCTCAGAGGTGCGCAGGCCCATC
CGGGACCCCTGGTTTTGGGCCCTGTTCGTGTGGACGTACATTTCACTCGGCGCATCCTTCCTGCTCTGGTGGCTGCTGTCCACCGTGCGG
CCAGGCACCCAGGCCCTGGAGCCAGGGGCGGCCACCGAGGCTGAGGGCTTCCCTGGGAGCGGCCGGCCACCGCCCGAGCAGGCGTCTGGG
GCCACGCTGCAGAAGCTGCTCTCCTACACCAAGCCCGACGTGGCCTTCCTCGTGGCCGCCTCCTTCTTCCTCATCGTGGCAGCTCTGGGA
GAGACCTTCCTGCCCTACTACACGGGCCGCGCCATTGATGGCATCGTCATCCAGAAAAGCATGGATCAGTTCAGCACGGCTGTCGTCATC
GTGTGCCTGCTGGCCATTGGCAGCTCATTTGCCGCAGGTATTCGGGGCGGCATTTTTACCCTCATATTTGCCAGACTGAACATTCGCCTT
CGAAACTGTCTCTTCCGCTCACTGGTGTCCCAGGAGACAAGCTTCTTTGATGAGAACCGCACAGGGGACCTCATCTCCCGCCTGACCTCG
GACACCACCATGGTCAGCGACCTGGTCTCCCAGAACATCAATGTCTTCCTGCGGAACACAGTCAAGGTCACGGGCGTGGTGGTCTTCATG
TTCAGCCTCTCATGGCAGCTCTCCTTGGTCACCTTCATGGGCTTCCCCATCATCATGATGGTGTCCAACATCTACGGCAAGTACTACAAG
AGGCTCTCCAAAGAGGTCCAGAATGCCCTGGCCAGAGCGAGCAACACGGCGGAGGAGACCATCAGTGCCATGAAGACTGTCCGGAGCTTC
GCCAATGAGGAGGAGGAGGCAGAGGTGTACCTGCGGAAGCTGCAGCAGGTGTACAAGCTGAACAGGAAGGAGGCAGCTGCCTACATGTAC
TACGTCTGGGGCAGCGGGCTCACACTGCTGGTGGTCCAGGTCAGCATCCTCTACTACGGGGGCCACCTTGTCATCTCAGGCCAGATGACC
AGCGGCAACCTCATCGCCTTCATCATCTACGAGTTTGTCCTGGGAGATTGTATGGAGATTGGAACCAACCAGATGGCTGTGTGTGCCAAA
GCACAGAACAAACCTTTCTATGTGGTTGCAGAAAGTTTCAAGTTTGTCCGGCTCTTTCCACTAAACCAGCAAGACGTCCCAGATAAGTTT
AAGTATAAGGCAGACACTCTCAAGGTCGCGCAGACTGGACAAGACCTCAAAGAGGAGCATCCGTGGGTCGACTACACTGCCCCTTCCTTA
ATCACTCTGCTGTTTACAGACCTGGGCGTGCTGACACCCTCAGCAGTCAGCGATGAGCTCATCAAGCTCTATCTGTAACCTGTGAGCCCT

>224_224_2_ABCB9-EIF2B1_ABCB9_chr12_123428938_ENST00000280560_EIF2B1_chr12_124107308_ENST00000539951_length(amino acids)=568AA_BP=472
MAFSTRPPPTSRMRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCLLLGATIGVAKNSALGPRR
LRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALFVWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQ
ASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLN
IRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGK
YYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTLLVVQVSILYYGGHLVISG
QMTSGNLIAFIIYEFVLGDCMEIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQDLKEEHPWVDYTA

--------------------------------------------------------------
>224_224_3_ABCB9-EIF2B1_ABCB9_chr12_123428938_ENST00000344275_EIF2B1_chr12_124107308_ENST00000424014_length(transcript)=3282nt_BP=1641nt
CTCAGCTCCGACCTTGCAGCGGCGCAGCGCGGGTGGGAGGCGGGGAGGAGCAGCGGGAAGAGCGGAGCGAGGACCGCGTCCGGCGCAGTC
TTCAATGAGCAGCGCGGAAACTGCACCCCAGACCCGAGCCTGCTGCGCGCCCCCTCCCAGAGCTCACCTGGTGCCAGGTAACAGGCCTGG
CCTCGCCCTGTGGATGATGATGGCCTTGCCCCCGTGAGCTACAACCTGGCCTTCAGCACCCGCCCACCTCCAACCAGCAGGATGCGGCTG
TGGAAGGCGGTGGTGGTGACTTTGGCCTTCATGAGTGTGGACATCTGCGTGACCACGGCCATCTATGTCTTCAGCCACCTGGACCGCAGC
CTCCTGGAGGACATCCGCCACTTCAACATCTTTGACTCGGTGCTGGATCTCTGGGCAGCCTGCCTGTACCGCAGCTGCCTGCTGCTGGGA
GCCACCATTGGTGTGGCCAAGAACAGTGCGCTGGGGCCCCGGCGGCTGCGGGCCTCGTGGCTGGTCATCACCCTCGTGTGCCTCTTCGTG
GGCATCTATGCCATGGTGAAGCTGCTGCTCTTCTCAGAGGTGCGCAGGCCCATCCGGGACCCCTGGTTTTGGGCCCTGTTCGTGTGGACG
TACATTTCACTCGGCGCATCCTTCCTGCTCTGGTGGCTGCTGTCCACCGTGCGGCCAGGCACCCAGGCCCTGGAGCCAGGGGCGGCCACC
GAGGCTGAGGGCTTCCCTGGGAGCGGCCGGCCACCGCCCGAGCAGGCGTCTGGGGCCACGCTGCAGAAGCTGCTCTCCTACACCAAGCCC
GACGTGGCCTTCCTCGTGGCCGCCTCCTTCTTCCTCATCGTGGCAGCTCTGGGAGAGACCTTCCTGCCCTACTACACGGGCCGCGCCATT
GATGGCATCGTCATCCAGAAAAGCATGGATCAGTTCAGCACGGCTGTCGTCATCGTGTGCCTGCTGGCCATTGGCAGCTCATTTGCCGCA
GGTATTCGGGGCGGCATTTTTACCCTCATATTTGCCAGACTGAACATTCGCCTTCGAAACTGTCTCTTCCGCTCACTGGTGTCCCAGGAG
ACAAGCTTCTTTGATGAGAACCGCACAGGGGACCTCATCTCCCGCCTGACCTCGGACACCACCATGGTCAGCGACCTGGTCTCCCAGAAC
ATCAATGTCTTCCTGCGGAACACAGTCAAGGTCACGGGCGTGGTGGTCTTCATGTTCAGCCTCTCATGGCAGCTCTCCTTGGTCACCTTC
ATGGGCTTCCCCATCATCATGATGGTGTCCAACATCTACGGCAAGTACTACAAGAGGCTCTCCAAAGAGGTCCAGAATGCCCTGGCCAGA
GCGAGCAACACGGCGGAGGAGACCATCAGTGCCATGAAGACTGTCCGGAGCTTCGCCAATGAGGAGGAGGAGGCAGAGGTGTACCTGCGG
AAGCTGCAGCAGGTGTACAAGCTGAACAGGAAGGAGGCAGCTGCCTACATGTACTACGTCTGGGGCAGCGGGCTCACACTGCTGGTGGTC
CAGGTCAGCATCCTCTACTACGGGGGCCACCTTGTCATCTCAGGCCAGATGACCAGCGGCAACCTCATCGCCTTCATCATCTACGAGTTT
GTCCTGGGAGATTGTATGGAGATTGGAACCAACCAGATGGCTGTGTGTGCCAAAGCACAGAACAAACCTTTCTATGTGGTTGCAGAAAGT
TTCAAGTTTGTCCGGCTCTTTCCACTAAACCAGCAAGACGTCCCAGATAAGTTTAAGTATAAGGCAGACACTCTCAAGGTCGCGCAGACT
GGACAAGACCTCAAAGAGGAGCATCCGTGGGTCGACTACACTGCCCCTTCCTTAATCACTCTGCTGTTTACAGACCTGGGCGTGCTGACA
CCCTCAGCAGTCAGCGATGAGCTCATCAAGCTCTATCTGTAACCTGTGAGCCCTTTCCTGCCAAGGTGCAGCTTACGTAGTTGAGGCAGG
GTGAGTAGCTGCTTGACACCCCAGTGAGTCAGGCCAAAACTGAGATGTGTTTAATGAAGATTTATGGAGTAAGGACTTAAAATCATACAT
CTTGGAGAACCTTTCTTACTCATTTCAGTCCCATCTAAAAATGTGTCAGCTATTCTAAATCCCAACTTAAATTGTTCTTACGGTTTCTAG
AAACTTTCCTTTTCAGTTTCCAGAAATACAAGTTAGATAATTGGCTACTTAACTGATGAAAGATGAGCCCAAGTCCACCTGTCTTCATCC
TCCCCTGCACTCCAGACTGATCTGCCTAAAGCACGCGAGATGCAGGCGAAAAGCAGCCACACCCCTCTGCCACAAATGACCAACAGCTGG
TCAGGACGTTACACGCGGTGCCTTGTAAGAGGCAAGAAACACTTGCTGAATCTGCATCTGGCTTCCAGTGGTAAGCACATTCCTCAGCAG
GATCAAGCCAAACAGTAAAAACTACCAAGAGAACACGAGGAAGGCAGAAACGATGTTTAGCAACAGTATTCTGCATGGTTCACTGCTTAA
GAAAATGCCTTCTGGAATATTTGTAAACTGAAATTCTGTATGTGTAAGAGATGTTTAAATATGTTTGGGTCCTAAACAGCTTTTTAAAAT
TATACTTGGGAATAAATTCAGCATCTTTTCAAATAAACTCTATGAAAGACGCTGATGTGGTGTTGCATCAATACTGCAAGCTGACCAGGC
CATCTAGGGGAAAACACTGTCCAGCTACATTTACACACTTAAGACCCAGGCAATCAGGACACCATTTATTCAACAGGAGGCATAAAAACT
ATAATTCTCTTTCCCGGAATATGACTTAATCCCTCTGTTTTTCAGCTATTCACCAATAAAACAATACTGTGACTATTAACACAGAAAAAC
CCCAGCACATTAGCCACCCCTGCAGGACATCAAAGGATAACTGAAGCCCAGGGCCAAGCACATTCAGGAGGTCAAATGCCTGAAGATACT
GAGGAATGGTTTTGAAAATCAGAAGTCAAGAAGACTTCTGTATCTTTATGTTTAAAAATAACTATAAAATAGCCTCAGAAAAAAGAGCTT
ATATATATATATATATATATATATATATATATATATATATATATATAATATGTACATATGTCTATATGTGACCCATCATGATAAATACTG
ACATCTATTATTTACACTCAAATAATTTTACATTTTCTTCTGTTAGACTACTCCAAGACTGGAATTGTTTTGTTTTGTTGTTTTTAATGA

>224_224_3_ABCB9-EIF2B1_ABCB9_chr12_123428938_ENST00000344275_EIF2B1_chr12_124107308_ENST00000424014_length(amino acids)=568AA_BP=472
MAFSTRPPPTSRMRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCLLLGATIGVAKNSALGPRR
LRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALFVWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQ
ASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLN
IRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGK
YYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTLLVVQVSILYYGGHLVISG
QMTSGNLIAFIIYEFVLGDCMEIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQDLKEEHPWVDYTA

--------------------------------------------------------------
>224_224_4_ABCB9-EIF2B1_ABCB9_chr12_123428938_ENST00000344275_EIF2B1_chr12_124107308_ENST00000539951_length(transcript)=1950nt_BP=1641nt
CTCAGCTCCGACCTTGCAGCGGCGCAGCGCGGGTGGGAGGCGGGGAGGAGCAGCGGGAAGAGCGGAGCGAGGACCGCGTCCGGCGCAGTC
TTCAATGAGCAGCGCGGAAACTGCACCCCAGACCCGAGCCTGCTGCGCGCCCCCTCCCAGAGCTCACCTGGTGCCAGGTAACAGGCCTGG
CCTCGCCCTGTGGATGATGATGGCCTTGCCCCCGTGAGCTACAACCTGGCCTTCAGCACCCGCCCACCTCCAACCAGCAGGATGCGGCTG
TGGAAGGCGGTGGTGGTGACTTTGGCCTTCATGAGTGTGGACATCTGCGTGACCACGGCCATCTATGTCTTCAGCCACCTGGACCGCAGC
CTCCTGGAGGACATCCGCCACTTCAACATCTTTGACTCGGTGCTGGATCTCTGGGCAGCCTGCCTGTACCGCAGCTGCCTGCTGCTGGGA
GCCACCATTGGTGTGGCCAAGAACAGTGCGCTGGGGCCCCGGCGGCTGCGGGCCTCGTGGCTGGTCATCACCCTCGTGTGCCTCTTCGTG
GGCATCTATGCCATGGTGAAGCTGCTGCTCTTCTCAGAGGTGCGCAGGCCCATCCGGGACCCCTGGTTTTGGGCCCTGTTCGTGTGGACG
TACATTTCACTCGGCGCATCCTTCCTGCTCTGGTGGCTGCTGTCCACCGTGCGGCCAGGCACCCAGGCCCTGGAGCCAGGGGCGGCCACC
GAGGCTGAGGGCTTCCCTGGGAGCGGCCGGCCACCGCCCGAGCAGGCGTCTGGGGCCACGCTGCAGAAGCTGCTCTCCTACACCAAGCCC
GACGTGGCCTTCCTCGTGGCCGCCTCCTTCTTCCTCATCGTGGCAGCTCTGGGAGAGACCTTCCTGCCCTACTACACGGGCCGCGCCATT
GATGGCATCGTCATCCAGAAAAGCATGGATCAGTTCAGCACGGCTGTCGTCATCGTGTGCCTGCTGGCCATTGGCAGCTCATTTGCCGCA
GGTATTCGGGGCGGCATTTTTACCCTCATATTTGCCAGACTGAACATTCGCCTTCGAAACTGTCTCTTCCGCTCACTGGTGTCCCAGGAG
ACAAGCTTCTTTGATGAGAACCGCACAGGGGACCTCATCTCCCGCCTGACCTCGGACACCACCATGGTCAGCGACCTGGTCTCCCAGAAC
ATCAATGTCTTCCTGCGGAACACAGTCAAGGTCACGGGCGTGGTGGTCTTCATGTTCAGCCTCTCATGGCAGCTCTCCTTGGTCACCTTC
ATGGGCTTCCCCATCATCATGATGGTGTCCAACATCTACGGCAAGTACTACAAGAGGCTCTCCAAAGAGGTCCAGAATGCCCTGGCCAGA
GCGAGCAACACGGCGGAGGAGACCATCAGTGCCATGAAGACTGTCCGGAGCTTCGCCAATGAGGAGGAGGAGGCAGAGGTGTACCTGCGG
AAGCTGCAGCAGGTGTACAAGCTGAACAGGAAGGAGGCAGCTGCCTACATGTACTACGTCTGGGGCAGCGGGCTCACACTGCTGGTGGTC
CAGGTCAGCATCCTCTACTACGGGGGCCACCTTGTCATCTCAGGCCAGATGACCAGCGGCAACCTCATCGCCTTCATCATCTACGAGTTT
GTCCTGGGAGATTGTATGGAGATTGGAACCAACCAGATGGCTGTGTGTGCCAAAGCACAGAACAAACCTTTCTATGTGGTTGCAGAAAGT
TTCAAGTTTGTCCGGCTCTTTCCACTAAACCAGCAAGACGTCCCAGATAAGTTTAAGTATAAGGCAGACACTCTCAAGGTCGCGCAGACT
GGACAAGACCTCAAAGAGGAGCATCCGTGGGTCGACTACACTGCCCCTTCCTTAATCACTCTGCTGTTTACAGACCTGGGCGTGCTGACA

>224_224_4_ABCB9-EIF2B1_ABCB9_chr12_123428938_ENST00000344275_EIF2B1_chr12_124107308_ENST00000539951_length(amino acids)=568AA_BP=472
MAFSTRPPPTSRMRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCLLLGATIGVAKNSALGPRR
LRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALFVWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQ
ASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLN
IRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGK
YYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTLLVVQVSILYYGGHLVISG
QMTSGNLIAFIIYEFVLGDCMEIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQDLKEEHPWVDYTA

--------------------------------------------------------------
>224_224_5_ABCB9-EIF2B1_ABCB9_chr12_123428938_ENST00000442833_EIF2B1_chr12_124107308_ENST00000424014_length(transcript)=3282nt_BP=1641nt
CTCAGCTCCGACCTTGCAGCGGCGCAGCGCGGGTGGGAGGCGGGGAGGAGCAGCGGGAAGAGCGGAGCGAGGACCGCGTCCGGCGCAGTC
TTCAATGAGCAGCGCGGAAACTGCACCCCAGACCCGAGCCTGCTGCGCGCCCCCTCCCAGAGCTCACCTGGTGCCAGGTAACAGGCCTGG
CCTCGCCCTGTGGATGATGATGGCCTTGCCCCCGTGAGCTACAACCTGGCCTTCAGCACCCGCCCACCTCCAACCAGCAGGATGCGGCTG
TGGAAGGCGGTGGTGGTGACTTTGGCCTTCATGAGTGTGGACATCTGCGTGACCACGGCCATCTATGTCTTCAGCCACCTGGACCGCAGC
CTCCTGGAGGACATCCGCCACTTCAACATCTTTGACTCGGTGCTGGATCTCTGGGCAGCCTGCCTGTACCGCAGCTGCCTGCTGCTGGGA
GCCACCATTGGTGTGGCCAAGAACAGTGCGCTGGGGCCCCGGCGGCTGCGGGCCTCGTGGCTGGTCATCACCCTCGTGTGCCTCTTCGTG
GGCATCTATGCCATGGTGAAGCTGCTGCTCTTCTCAGAGGTGCGCAGGCCCATCCGGGACCCCTGGTTTTGGGCCCTGTTCGTGTGGACG
TACATTTCACTCGGCGCATCCTTCCTGCTCTGGTGGCTGCTGTCCACCGTGCGGCCAGGCACCCAGGCCCTGGAGCCAGGGGCGGCCACC
GAGGCTGAGGGCTTCCCTGGGAGCGGCCGGCCACCGCCCGAGCAGGCGTCTGGGGCCACGCTGCAGAAGCTGCTCTCCTACACCAAGCCC
GACGTGGCCTTCCTCGTGGCCGCCTCCTTCTTCCTCATCGTGGCAGCTCTGGGAGAGACCTTCCTGCCCTACTACACGGGCCGCGCCATT
GATGGCATCGTCATCCAGAAAAGCATGGATCAGTTCAGCACGGCTGTCGTCATCGTGTGCCTGCTGGCCATTGGCAGCTCATTTGCCGCA
GGTATTCGGGGCGGCATTTTTACCCTCATATTTGCCAGACTGAACATTCGCCTTCGAAACTGTCTCTTCCGCTCACTGGTGTCCCAGGAG
ACAAGCTTCTTTGATGAGAACCGCACAGGGGACCTCATCTCCCGCCTGACCTCGGACACCACCATGGTCAGCGACCTGGTCTCCCAGAAC
ATCAATGTCTTCCTGCGGAACACAGTCAAGGTCACGGGCGTGGTGGTCTTCATGTTCAGCCTCTCATGGCAGCTCTCCTTGGTCACCTTC
ATGGGCTTCCCCATCATCATGATGGTGTCCAACATCTACGGCAAGTACTACAAGAGGCTCTCCAAAGAGGTCCAGAATGCCCTGGCCAGA
GCGAGCAACACGGCGGAGGAGACCATCAGTGCCATGAAGACTGTCCGGAGCTTCGCCAATGAGGAGGAGGAGGCAGAGGTGTACCTGCGG
AAGCTGCAGCAGGTGTACAAGCTGAACAGGAAGGAGGCAGCTGCCTACATGTACTACGTCTGGGGCAGCGGGCTCACACTGCTGGTGGTC
CAGGTCAGCATCCTCTACTACGGGGGCCACCTTGTCATCTCAGGCCAGATGACCAGCGGCAACCTCATCGCCTTCATCATCTACGAGTTT
GTCCTGGGAGATTGTATGGAGATTGGAACCAACCAGATGGCTGTGTGTGCCAAAGCACAGAACAAACCTTTCTATGTGGTTGCAGAAAGT
TTCAAGTTTGTCCGGCTCTTTCCACTAAACCAGCAAGACGTCCCAGATAAGTTTAAGTATAAGGCAGACACTCTCAAGGTCGCGCAGACT
GGACAAGACCTCAAAGAGGAGCATCCGTGGGTCGACTACACTGCCCCTTCCTTAATCACTCTGCTGTTTACAGACCTGGGCGTGCTGACA
CCCTCAGCAGTCAGCGATGAGCTCATCAAGCTCTATCTGTAACCTGTGAGCCCTTTCCTGCCAAGGTGCAGCTTACGTAGTTGAGGCAGG
GTGAGTAGCTGCTTGACACCCCAGTGAGTCAGGCCAAAACTGAGATGTGTTTAATGAAGATTTATGGAGTAAGGACTTAAAATCATACAT
CTTGGAGAACCTTTCTTACTCATTTCAGTCCCATCTAAAAATGTGTCAGCTATTCTAAATCCCAACTTAAATTGTTCTTACGGTTTCTAG
AAACTTTCCTTTTCAGTTTCCAGAAATACAAGTTAGATAATTGGCTACTTAACTGATGAAAGATGAGCCCAAGTCCACCTGTCTTCATCC
TCCCCTGCACTCCAGACTGATCTGCCTAAAGCACGCGAGATGCAGGCGAAAAGCAGCCACACCCCTCTGCCACAAATGACCAACAGCTGG
TCAGGACGTTACACGCGGTGCCTTGTAAGAGGCAAGAAACACTTGCTGAATCTGCATCTGGCTTCCAGTGGTAAGCACATTCCTCAGCAG
GATCAAGCCAAACAGTAAAAACTACCAAGAGAACACGAGGAAGGCAGAAACGATGTTTAGCAACAGTATTCTGCATGGTTCACTGCTTAA
GAAAATGCCTTCTGGAATATTTGTAAACTGAAATTCTGTATGTGTAAGAGATGTTTAAATATGTTTGGGTCCTAAACAGCTTTTTAAAAT
TATACTTGGGAATAAATTCAGCATCTTTTCAAATAAACTCTATGAAAGACGCTGATGTGGTGTTGCATCAATACTGCAAGCTGACCAGGC
CATCTAGGGGAAAACACTGTCCAGCTACATTTACACACTTAAGACCCAGGCAATCAGGACACCATTTATTCAACAGGAGGCATAAAAACT
ATAATTCTCTTTCCCGGAATATGACTTAATCCCTCTGTTTTTCAGCTATTCACCAATAAAACAATACTGTGACTATTAACACAGAAAAAC
CCCAGCACATTAGCCACCCCTGCAGGACATCAAAGGATAACTGAAGCCCAGGGCCAAGCACATTCAGGAGGTCAAATGCCTGAAGATACT
GAGGAATGGTTTTGAAAATCAGAAGTCAAGAAGACTTCTGTATCTTTATGTTTAAAAATAACTATAAAATAGCCTCAGAAAAAAGAGCTT
ATATATATATATATATATATATATATATATATATATATATATATATAATATGTACATATGTCTATATGTGACCCATCATGATAAATACTG
ACATCTATTATTTACACTCAAATAATTTTACATTTTCTTCTGTTAGACTACTCCAAGACTGGAATTGTTTTGTTTTGTTGTTTTTAATGA

>224_224_5_ABCB9-EIF2B1_ABCB9_chr12_123428938_ENST00000442833_EIF2B1_chr12_124107308_ENST00000424014_length(amino acids)=568AA_BP=472
MAFSTRPPPTSRMRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCLLLGATIGVAKNSALGPRR
LRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALFVWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQ
ASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLN
IRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGK
YYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTLLVVQVSILYYGGHLVISG
QMTSGNLIAFIIYEFVLGDCMEIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQDLKEEHPWVDYTA

--------------------------------------------------------------
>224_224_6_ABCB9-EIF2B1_ABCB9_chr12_123428938_ENST00000442833_EIF2B1_chr12_124107308_ENST00000539951_length(transcript)=1950nt_BP=1641nt
CTCAGCTCCGACCTTGCAGCGGCGCAGCGCGGGTGGGAGGCGGGGAGGAGCAGCGGGAAGAGCGGAGCGAGGACCGCGTCCGGCGCAGTC
TTCAATGAGCAGCGCGGAAACTGCACCCCAGACCCGAGCCTGCTGCGCGCCCCCTCCCAGAGCTCACCTGGTGCCAGGTAACAGGCCTGG
CCTCGCCCTGTGGATGATGATGGCCTTGCCCCCGTGAGCTACAACCTGGCCTTCAGCACCCGCCCACCTCCAACCAGCAGGATGCGGCTG
TGGAAGGCGGTGGTGGTGACTTTGGCCTTCATGAGTGTGGACATCTGCGTGACCACGGCCATCTATGTCTTCAGCCACCTGGACCGCAGC
CTCCTGGAGGACATCCGCCACTTCAACATCTTTGACTCGGTGCTGGATCTCTGGGCAGCCTGCCTGTACCGCAGCTGCCTGCTGCTGGGA
GCCACCATTGGTGTGGCCAAGAACAGTGCGCTGGGGCCCCGGCGGCTGCGGGCCTCGTGGCTGGTCATCACCCTCGTGTGCCTCTTCGTG
GGCATCTATGCCATGGTGAAGCTGCTGCTCTTCTCAGAGGTGCGCAGGCCCATCCGGGACCCCTGGTTTTGGGCCCTGTTCGTGTGGACG
TACATTTCACTCGGCGCATCCTTCCTGCTCTGGTGGCTGCTGTCCACCGTGCGGCCAGGCACCCAGGCCCTGGAGCCAGGGGCGGCCACC
GAGGCTGAGGGCTTCCCTGGGAGCGGCCGGCCACCGCCCGAGCAGGCGTCTGGGGCCACGCTGCAGAAGCTGCTCTCCTACACCAAGCCC
GACGTGGCCTTCCTCGTGGCCGCCTCCTTCTTCCTCATCGTGGCAGCTCTGGGAGAGACCTTCCTGCCCTACTACACGGGCCGCGCCATT
GATGGCATCGTCATCCAGAAAAGCATGGATCAGTTCAGCACGGCTGTCGTCATCGTGTGCCTGCTGGCCATTGGCAGCTCATTTGCCGCA
GGTATTCGGGGCGGCATTTTTACCCTCATATTTGCCAGACTGAACATTCGCCTTCGAAACTGTCTCTTCCGCTCACTGGTGTCCCAGGAG
ACAAGCTTCTTTGATGAGAACCGCACAGGGGACCTCATCTCCCGCCTGACCTCGGACACCACCATGGTCAGCGACCTGGTCTCCCAGAAC
ATCAATGTCTTCCTGCGGAACACAGTCAAGGTCACGGGCGTGGTGGTCTTCATGTTCAGCCTCTCATGGCAGCTCTCCTTGGTCACCTTC
ATGGGCTTCCCCATCATCATGATGGTGTCCAACATCTACGGCAAGTACTACAAGAGGCTCTCCAAAGAGGTCCAGAATGCCCTGGCCAGA
GCGAGCAACACGGCGGAGGAGACCATCAGTGCCATGAAGACTGTCCGGAGCTTCGCCAATGAGGAGGAGGAGGCAGAGGTGTACCTGCGG
AAGCTGCAGCAGGTGTACAAGCTGAACAGGAAGGAGGCAGCTGCCTACATGTACTACGTCTGGGGCAGCGGGCTCACACTGCTGGTGGTC
CAGGTCAGCATCCTCTACTACGGGGGCCACCTTGTCATCTCAGGCCAGATGACCAGCGGCAACCTCATCGCCTTCATCATCTACGAGTTT
GTCCTGGGAGATTGTATGGAGATTGGAACCAACCAGATGGCTGTGTGTGCCAAAGCACAGAACAAACCTTTCTATGTGGTTGCAGAAAGT
TTCAAGTTTGTCCGGCTCTTTCCACTAAACCAGCAAGACGTCCCAGATAAGTTTAAGTATAAGGCAGACACTCTCAAGGTCGCGCAGACT
GGACAAGACCTCAAAGAGGAGCATCCGTGGGTCGACTACACTGCCCCTTCCTTAATCACTCTGCTGTTTACAGACCTGGGCGTGCTGACA

>224_224_6_ABCB9-EIF2B1_ABCB9_chr12_123428938_ENST00000442833_EIF2B1_chr12_124107308_ENST00000539951_length(amino acids)=568AA_BP=472
MAFSTRPPPTSRMRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCLLLGATIGVAKNSALGPRR
LRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALFVWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQ
ASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLN
IRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGK
YYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTLLVVQVSILYYGGHLVISG
QMTSGNLIAFIIYEFVLGDCMEIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQDLKEEHPWVDYTA

--------------------------------------------------------------
>224_224_7_ABCB9-EIF2B1_ABCB9_chr12_123428938_ENST00000540285_EIF2B1_chr12_124107308_ENST00000424014_length(transcript)=3322nt_BP=1681nt
GCCCCGCCCCGTCCATCAGCCTGTCTCAACGCACGCCAGTCTCAGCTCCGACCTTGCAGCGGCGCAGCGCGGGTGGGAGGCGGGGAGGAG
CAGCGGGAAGAGCGGAGCGAGGACCGCGTCCGGCGCAGTCTTCAATGAGCAGCGCGGAAACTGCACCCCAGACCCGAGCCTGCTGCGCGC
CCCCTCCCAGAGCTCACCTGGTGCCAGGTAACAGGCCTGGCCTCGCCCTGTGGATGATGATGGCCTTGCCCCCGTGAGCTACAACCTGGC
CTTCAGCACCCGCCCACCTCCAACCAGCAGGATGCGGCTGTGGAAGGCGGTGGTGGTGACTTTGGCCTTCATGAGTGTGGACATCTGCGT
GACCACGGCCATCTATGTCTTCAGCCACCTGGACCGCAGCCTCCTGGAGGACATCCGCCACTTCAACATCTTTGACTCGGTGCTGGATCT
CTGGGCAGCCTGCCTGTACCGCAGCTGCCTGCTGCTGGGAGCCACCATTGGTGTGGCCAAGAACAGTGCGCTGGGGCCCCGGCGGCTGCG
GGCCTCGTGGCTGGTCATCACCCTCGTGTGCCTCTTCGTGGGCATCTATGCCATGGTGAAGCTGCTGCTCTTCTCAGAGGTGCGCAGGCC
CATCCGGGACCCCTGGTTTTGGGCCCTGTTCGTGTGGACGTACATTTCACTCGGCGCATCCTTCCTGCTCTGGTGGCTGCTGTCCACCGT
GCGGCCAGGCACCCAGGCCCTGGAGCCAGGGGCGGCCACCGAGGCTGAGGGCTTCCCTGGGAGCGGCCGGCCACCGCCCGAGCAGGCGTC
TGGGGCCACGCTGCAGAAGCTGCTCTCCTACACCAAGCCCGACGTGGCCTTCCTCGTGGCCGCCTCCTTCTTCCTCATCGTGGCAGCTCT
GGGAGAGACCTTCCTGCCCTACTACACGGGCCGCGCCATTGATGGCATCGTCATCCAGAAAAGCATGGATCAGTTCAGCACGGCTGTCGT
CATCGTGTGCCTGCTGGCCATTGGCAGCTCATTTGCCGCAGGTATTCGGGGCGGCATTTTTACCCTCATATTTGCCAGACTGAACATTCG
CCTTCGAAACTGTCTCTTCCGCTCACTGGTGTCCCAGGAGACAAGCTTCTTTGATGAGAACCGCACAGGGGACCTCATCTCCCGCCTGAC
CTCGGACACCACCATGGTCAGCGACCTGGTCTCCCAGAACATCAATGTCTTCCTGCGGAACACAGTCAAGGTCACGGGCGTGGTGGTCTT
CATGTTCAGCCTCTCATGGCAGCTCTCCTTGGTCACCTTCATGGGCTTCCCCATCATCATGATGGTGTCCAACATCTACGGCAAGTACTA
CAAGAGGCTCTCCAAAGAGGTCCAGAATGCCCTGGCCAGAGCGAGCAACACGGCGGAGGAGACCATCAGTGCCATGAAGACTGTCCGGAG
CTTCGCCAATGAGGAGGAGGAGGCAGAGGTGTACCTGCGGAAGCTGCAGCAGGTGTACAAGCTGAACAGGAAGGAGGCAGCTGCCTACAT
GTACTACGTCTGGGGCAGCGGGCTCACACTGCTGGTGGTCCAGGTCAGCATCCTCTACTACGGGGGCCACCTTGTCATCTCAGGCCAGAT
GACCAGCGGCAACCTCATCGCCTTCATCATCTACGAGTTTGTCCTGGGAGATTGTATGGAGATTGGAACCAACCAGATGGCTGTGTGTGC
CAAAGCACAGAACAAACCTTTCTATGTGGTTGCAGAAAGTTTCAAGTTTGTCCGGCTCTTTCCACTAAACCAGCAAGACGTCCCAGATAA
GTTTAAGTATAAGGCAGACACTCTCAAGGTCGCGCAGACTGGACAAGACCTCAAAGAGGAGCATCCGTGGGTCGACTACACTGCCCCTTC
CTTAATCACTCTGCTGTTTACAGACCTGGGCGTGCTGACACCCTCAGCAGTCAGCGATGAGCTCATCAAGCTCTATCTGTAACCTGTGAG
CCCTTTCCTGCCAAGGTGCAGCTTACGTAGTTGAGGCAGGGTGAGTAGCTGCTTGACACCCCAGTGAGTCAGGCCAAAACTGAGATGTGT
TTAATGAAGATTTATGGAGTAAGGACTTAAAATCATACATCTTGGAGAACCTTTCTTACTCATTTCAGTCCCATCTAAAAATGTGTCAGC
TATTCTAAATCCCAACTTAAATTGTTCTTACGGTTTCTAGAAACTTTCCTTTTCAGTTTCCAGAAATACAAGTTAGATAATTGGCTACTT
AACTGATGAAAGATGAGCCCAAGTCCACCTGTCTTCATCCTCCCCTGCACTCCAGACTGATCTGCCTAAAGCACGCGAGATGCAGGCGAA
AAGCAGCCACACCCCTCTGCCACAAATGACCAACAGCTGGTCAGGACGTTACACGCGGTGCCTTGTAAGAGGCAAGAAACACTTGCTGAA
TCTGCATCTGGCTTCCAGTGGTAAGCACATTCCTCAGCAGGATCAAGCCAAACAGTAAAAACTACCAAGAGAACACGAGGAAGGCAGAAA
CGATGTTTAGCAACAGTATTCTGCATGGTTCACTGCTTAAGAAAATGCCTTCTGGAATATTTGTAAACTGAAATTCTGTATGTGTAAGAG
ATGTTTAAATATGTTTGGGTCCTAAACAGCTTTTTAAAATTATACTTGGGAATAAATTCAGCATCTTTTCAAATAAACTCTATGAAAGAC
GCTGATGTGGTGTTGCATCAATACTGCAAGCTGACCAGGCCATCTAGGGGAAAACACTGTCCAGCTACATTTACACACTTAAGACCCAGG
CAATCAGGACACCATTTATTCAACAGGAGGCATAAAAACTATAATTCTCTTTCCCGGAATATGACTTAATCCCTCTGTTTTTCAGCTATT
CACCAATAAAACAATACTGTGACTATTAACACAGAAAAACCCCAGCACATTAGCCACCCCTGCAGGACATCAAAGGATAACTGAAGCCCA
GGGCCAAGCACATTCAGGAGGTCAAATGCCTGAAGATACTGAGGAATGGTTTTGAAAATCAGAAGTCAAGAAGACTTCTGTATCTTTATG
TTTAAAAATAACTATAAAATAGCCTCAGAAAAAAGAGCTTATATATATATATATATATATATATATATATATATATATATATATATAATA
TGTACATATGTCTATATGTGACCCATCATGATAAATACTGACATCTATTATTTACACTCAAATAATTTTACATTTTCTTCTGTTAGACTA

>224_224_7_ABCB9-EIF2B1_ABCB9_chr12_123428938_ENST00000540285_EIF2B1_chr12_124107308_ENST00000424014_length(amino acids)=568AA_BP=472
MAFSTRPPPTSRMRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCLLLGATIGVAKNSALGPRR
LRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALFVWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQ
ASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLN
IRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGK
YYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTLLVVQVSILYYGGHLVISG
QMTSGNLIAFIIYEFVLGDCMEIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQDLKEEHPWVDYTA

--------------------------------------------------------------
>224_224_8_ABCB9-EIF2B1_ABCB9_chr12_123428938_ENST00000540285_EIF2B1_chr12_124107308_ENST00000539951_length(transcript)=1990nt_BP=1681nt
GCCCCGCCCCGTCCATCAGCCTGTCTCAACGCACGCCAGTCTCAGCTCCGACCTTGCAGCGGCGCAGCGCGGGTGGGAGGCGGGGAGGAG
CAGCGGGAAGAGCGGAGCGAGGACCGCGTCCGGCGCAGTCTTCAATGAGCAGCGCGGAAACTGCACCCCAGACCCGAGCCTGCTGCGCGC
CCCCTCCCAGAGCTCACCTGGTGCCAGGTAACAGGCCTGGCCTCGCCCTGTGGATGATGATGGCCTTGCCCCCGTGAGCTACAACCTGGC
CTTCAGCACCCGCCCACCTCCAACCAGCAGGATGCGGCTGTGGAAGGCGGTGGTGGTGACTTTGGCCTTCATGAGTGTGGACATCTGCGT
GACCACGGCCATCTATGTCTTCAGCCACCTGGACCGCAGCCTCCTGGAGGACATCCGCCACTTCAACATCTTTGACTCGGTGCTGGATCT
CTGGGCAGCCTGCCTGTACCGCAGCTGCCTGCTGCTGGGAGCCACCATTGGTGTGGCCAAGAACAGTGCGCTGGGGCCCCGGCGGCTGCG
GGCCTCGTGGCTGGTCATCACCCTCGTGTGCCTCTTCGTGGGCATCTATGCCATGGTGAAGCTGCTGCTCTTCTCAGAGGTGCGCAGGCC
CATCCGGGACCCCTGGTTTTGGGCCCTGTTCGTGTGGACGTACATTTCACTCGGCGCATCCTTCCTGCTCTGGTGGCTGCTGTCCACCGT
GCGGCCAGGCACCCAGGCCCTGGAGCCAGGGGCGGCCACCGAGGCTGAGGGCTTCCCTGGGAGCGGCCGGCCACCGCCCGAGCAGGCGTC
TGGGGCCACGCTGCAGAAGCTGCTCTCCTACACCAAGCCCGACGTGGCCTTCCTCGTGGCCGCCTCCTTCTTCCTCATCGTGGCAGCTCT
GGGAGAGACCTTCCTGCCCTACTACACGGGCCGCGCCATTGATGGCATCGTCATCCAGAAAAGCATGGATCAGTTCAGCACGGCTGTCGT
CATCGTGTGCCTGCTGGCCATTGGCAGCTCATTTGCCGCAGGTATTCGGGGCGGCATTTTTACCCTCATATTTGCCAGACTGAACATTCG
CCTTCGAAACTGTCTCTTCCGCTCACTGGTGTCCCAGGAGACAAGCTTCTTTGATGAGAACCGCACAGGGGACCTCATCTCCCGCCTGAC
CTCGGACACCACCATGGTCAGCGACCTGGTCTCCCAGAACATCAATGTCTTCCTGCGGAACACAGTCAAGGTCACGGGCGTGGTGGTCTT
CATGTTCAGCCTCTCATGGCAGCTCTCCTTGGTCACCTTCATGGGCTTCCCCATCATCATGATGGTGTCCAACATCTACGGCAAGTACTA
CAAGAGGCTCTCCAAAGAGGTCCAGAATGCCCTGGCCAGAGCGAGCAACACGGCGGAGGAGACCATCAGTGCCATGAAGACTGTCCGGAG
CTTCGCCAATGAGGAGGAGGAGGCAGAGGTGTACCTGCGGAAGCTGCAGCAGGTGTACAAGCTGAACAGGAAGGAGGCAGCTGCCTACAT
GTACTACGTCTGGGGCAGCGGGCTCACACTGCTGGTGGTCCAGGTCAGCATCCTCTACTACGGGGGCCACCTTGTCATCTCAGGCCAGAT
GACCAGCGGCAACCTCATCGCCTTCATCATCTACGAGTTTGTCCTGGGAGATTGTATGGAGATTGGAACCAACCAGATGGCTGTGTGTGC
CAAAGCACAGAACAAACCTTTCTATGTGGTTGCAGAAAGTTTCAAGTTTGTCCGGCTCTTTCCACTAAACCAGCAAGACGTCCCAGATAA
GTTTAAGTATAAGGCAGACACTCTCAAGGTCGCGCAGACTGGACAAGACCTCAAAGAGGAGCATCCGTGGGTCGACTACACTGCCCCTTC
CTTAATCACTCTGCTGTTTACAGACCTGGGCGTGCTGACACCCTCAGCAGTCAGCGATGAGCTCATCAAGCTCTATCTGTAACCTGTGAG

>224_224_8_ABCB9-EIF2B1_ABCB9_chr12_123428938_ENST00000540285_EIF2B1_chr12_124107308_ENST00000539951_length(amino acids)=568AA_BP=472
MAFSTRPPPTSRMRLWKAVVVTLAFMSVDICVTTAIYVFSHLDRSLLEDIRHFNIFDSVLDLWAACLYRSCLLLGATIGVAKNSALGPRR
LRASWLVITLVCLFVGIYAMVKLLLFSEVRRPIRDPWFWALFVWTYISLGASFLLWWLLSTVRPGTQALEPGAATEAEGFPGSGRPPPEQ
ASGATLQKLLSYTKPDVAFLVAASFFLIVAALGETFLPYYTGRAIDGIVIQKSMDQFSTAVVIVCLLAIGSSFAAGIRGGIFTLIFARLN
IRLRNCLFRSLVSQETSFFDENRTGDLISRLTSDTTMVSDLVSQNINVFLRNTVKVTGVVVFMFSLSWQLSLVTFMGFPIIMMVSNIYGK
YYKRLSKEVQNALARASNTAEETISAMKTVRSFANEEEEAEVYLRKLQQVYKLNRKEAAAYMYYVWGSGLTLLVVQVSILYYGGHLVISG
QMTSGNLIAFIIYEFVLGDCMEIGTNQMAVCAKAQNKPFYVVAESFKFVRLFPLNQQDVPDKFKYKADTLKVAQTGQDLKEEHPWVDYTA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ABCB9-EIF2B1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ABCB9-EIF2B1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ABCB9-EIF2B1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource