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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DGCR2-SLC25A1 (FusionGDB2 ID:22415)

Fusion Gene Summary for DGCR2-SLC25A1

check button Fusion gene summary
Fusion gene informationFusion gene name: DGCR2-SLC25A1
Fusion gene ID: 22415
HgeneTgene
Gene symbol

DGCR2

SLC25A1

Gene ID

9993

6576

Gene nameDiGeorge syndrome critical region gene 2solute carrier family 25 member 1
SynonymsDGS-C|IDD|LAN|SEZ-12CMS23|CTP|D2L2AD|SEA|SLC20A3
Cytomap

22q11.21

22q11.21

Type of geneprotein-codingprotein-coding
Descriptionintegral membrane protein DGCR2/IDDDiGeorge syndrome critical region protein 2integral membrane protein deleted in DiGeorge syndrometricarboxylate transport protein, mitochondrialcitrate transport proteinsolute carrier family 20 (mitochondrial citrate transporter), member 3solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1tricarboxylate carrier protein
Modification date2020031320200320
UniProtAcc

P98153

P16260

Ensembl transtripts involved in fusion geneENST00000263196, ENST00000537045, 
ENST00000545799, ENST00000473832, 
ENST00000461267, ENST00000215882, 
ENST00000451283, 
Fusion gene scores* DoF score16 X 15 X 8=19205 X 5 X 2=50
# samples 216
** MAII scorelog2(21/1920*10)=-3.1926450779424
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/50*10)=0.263034405833794
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: DGCR2 [Title/Abstract] AND SLC25A1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDGCR2(19050715)-SLC25A1(19164463), # samples:2
Anticipated loss of major functional domain due to fusion event.DGCR2-SLC25A1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
DGCR2-SLC25A1 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
DGCR2-SLC25A1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
DGCR2-SLC25A1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across DGCR2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SLC25A1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CD-8526-01ADGCR2chr22

19050715

-SLC25A1chr22

19164463

-
ChimerDB4STADTCGA-CD-8526DGCR2chr22

19050714

-SLC25A1chr22

19164463

-


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Fusion Gene ORF analysis for DGCR2-SLC25A1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000263196ENST00000461267DGCR2chr22

19050715

-SLC25A1chr22

19164463

-
5CDS-5UTRENST00000263196ENST00000461267DGCR2chr22

19050714

-SLC25A1chr22

19164463

-
5CDS-5UTRENST00000537045ENST00000461267DGCR2chr22

19050715

-SLC25A1chr22

19164463

-
5CDS-5UTRENST00000537045ENST00000461267DGCR2chr22

19050714

-SLC25A1chr22

19164463

-
5CDS-5UTRENST00000545799ENST00000461267DGCR2chr22

19050715

-SLC25A1chr22

19164463

-
5CDS-5UTRENST00000545799ENST00000461267DGCR2chr22

19050714

-SLC25A1chr22

19164463

-
5UTR-3CDSENST00000473832ENST00000215882DGCR2chr22

19050715

-SLC25A1chr22

19164463

-
5UTR-3CDSENST00000473832ENST00000215882DGCR2chr22

19050714

-SLC25A1chr22

19164463

-
5UTR-3CDSENST00000473832ENST00000451283DGCR2chr22

19050715

-SLC25A1chr22

19164463

-
5UTR-3CDSENST00000473832ENST00000451283DGCR2chr22

19050714

-SLC25A1chr22

19164463

-
5UTR-5UTRENST00000473832ENST00000461267DGCR2chr22

19050715

-SLC25A1chr22

19164463

-
5UTR-5UTRENST00000473832ENST00000461267DGCR2chr22

19050714

-SLC25A1chr22

19164463

-
Frame-shiftENST00000545799ENST00000215882DGCR2chr22

19050715

-SLC25A1chr22

19164463

-
Frame-shiftENST00000545799ENST00000215882DGCR2chr22

19050714

-SLC25A1chr22

19164463

-
Frame-shiftENST00000545799ENST00000451283DGCR2chr22

19050715

-SLC25A1chr22

19164463

-
Frame-shiftENST00000545799ENST00000451283DGCR2chr22

19050714

-SLC25A1chr22

19164463

-
In-frameENST00000263196ENST00000215882DGCR2chr22

19050715

-SLC25A1chr22

19164463

-
In-frameENST00000263196ENST00000215882DGCR2chr22

19050714

-SLC25A1chr22

19164463

-
In-frameENST00000263196ENST00000451283DGCR2chr22

19050715

-SLC25A1chr22

19164463

-
In-frameENST00000263196ENST00000451283DGCR2chr22

19050714

-SLC25A1chr22

19164463

-
In-frameENST00000537045ENST00000215882DGCR2chr22

19050715

-SLC25A1chr22

19164463

-
In-frameENST00000537045ENST00000215882DGCR2chr22

19050714

-SLC25A1chr22

19164463

-
In-frameENST00000537045ENST00000451283DGCR2chr22

19050715

-SLC25A1chr22

19164463

-
In-frameENST00000537045ENST00000451283DGCR2chr22

19050714

-SLC25A1chr22

19164463

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000537045DGCR2chr2219050714-ENST00000215882SLC25A1chr2219164463-17087501687458409
ENST00000537045DGCR2chr2219050714-ENST00000451283SLC25A1chr2219164463-16977501687458409
ENST00000263196DGCR2chr2219050714-ENST00000215882SLC25A1chr2219164463-18318731810581409
ENST00000263196DGCR2chr2219050714-ENST00000451283SLC25A1chr2219164463-18208731810581409
ENST00000537045DGCR2chr2219050715-ENST00000215882SLC25A1chr2219164463-17087501687458409
ENST00000537045DGCR2chr2219050715-ENST00000451283SLC25A1chr2219164463-16977501687458409
ENST00000263196DGCR2chr2219050715-ENST00000215882SLC25A1chr2219164463-18318731810581409
ENST00000263196DGCR2chr2219050715-ENST00000451283SLC25A1chr2219164463-18208731810581409

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000537045ENST00000215882DGCR2chr2219050714-SLC25A1chr2219164463-0.006548060.99345195
ENST00000537045ENST00000451283DGCR2chr2219050714-SLC25A1chr2219164463-0.0065620160.99343795
ENST00000263196ENST00000215882DGCR2chr2219050714-SLC25A1chr2219164463-0.0132958960.9867041
ENST00000263196ENST00000451283DGCR2chr2219050714-SLC25A1chr2219164463-0.0132839280.98671603
ENST00000537045ENST00000215882DGCR2chr2219050715-SLC25A1chr2219164463-0.006548060.99345195
ENST00000537045ENST00000451283DGCR2chr2219050715-SLC25A1chr2219164463-0.0065620160.99343795
ENST00000263196ENST00000215882DGCR2chr2219050715-SLC25A1chr2219164463-0.0132958960.9867041
ENST00000263196ENST00000451283DGCR2chr2219050715-SLC25A1chr2219164463-0.0132839280.98671603

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Fusion Genomic Features for DGCR2-SLC25A1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for DGCR2-SLC25A1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:19050715/chr22:19164463)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DGCR2

P98153

SLC25A1

P16260

FUNCTION: Putative adhesion receptor, that could be involved in cell-cell or cell-matrix interactions required for normal cell differentiation and migration.FUNCTION: Required for the accumulation of coenzyme A in the mitochondrial matrix. {ECO:0000269|PubMed:11158296}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDGCR2chr22:19050714chr22:19164463ENST00000263196-51028_68208551.0DomainLDL-receptor class A
HgeneDGCR2chr22:19050714chr22:19164463ENST00000537045-4928_68167510.0DomainLDL-receptor class A
HgeneDGCR2chr22:19050715chr22:19164463ENST00000263196-51028_68208551.0DomainLDL-receptor class A
HgeneDGCR2chr22:19050715chr22:19164463ENST00000537045-4928_68167510.0DomainLDL-receptor class A
TgeneSLC25A1chr22:19050714chr22:19164463ENST0000021588249218_303175312.0RepeatNote=Solcar 3
TgeneSLC25A1chr22:19050715chr22:19164463ENST0000021588249218_303175312.0RepeatNote=Solcar 3
TgeneSLC25A1chr22:19050714chr22:19164463ENST0000021588249183_202175312.0TransmembraneHelical%3B Name%3D4
TgeneSLC25A1chr22:19050714chr22:19164463ENST0000021588249224_241175312.0TransmembraneHelical%3B Name%3D5
TgeneSLC25A1chr22:19050714chr22:19164463ENST0000021588249278_297175312.0TransmembraneHelical%3B Name%3D6
TgeneSLC25A1chr22:19050715chr22:19164463ENST0000021588249183_202175312.0TransmembraneHelical%3B Name%3D4
TgeneSLC25A1chr22:19050715chr22:19164463ENST0000021588249224_241175312.0TransmembraneHelical%3B Name%3D5
TgeneSLC25A1chr22:19050715chr22:19164463ENST0000021588249278_297175312.0TransmembraneHelical%3B Name%3D6

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDGCR2chr22:19050714chr22:19164463ENST00000263196-510115_241208551.0DomainC-type lectin
HgeneDGCR2chr22:19050714chr22:19164463ENST00000263196-510270_333208551.0DomainNote=VWFC
HgeneDGCR2chr22:19050714chr22:19164463ENST00000537045-49115_241167510.0DomainC-type lectin
HgeneDGCR2chr22:19050714chr22:19164463ENST00000537045-49270_333167510.0DomainNote=VWFC
HgeneDGCR2chr22:19050715chr22:19164463ENST00000263196-510115_241208551.0DomainC-type lectin
HgeneDGCR2chr22:19050715chr22:19164463ENST00000263196-510270_333208551.0DomainNote=VWFC
HgeneDGCR2chr22:19050715chr22:19164463ENST00000537045-49115_241167510.0DomainC-type lectin
HgeneDGCR2chr22:19050715chr22:19164463ENST00000537045-49270_333167510.0DomainNote=VWFC
HgeneDGCR2chr22:19050714chr22:19164463ENST00000263196-51021_349208551.0Topological domainExtracellular
HgeneDGCR2chr22:19050714chr22:19164463ENST00000263196-510369_550208551.0Topological domainCytoplasmic
HgeneDGCR2chr22:19050714chr22:19164463ENST00000537045-4921_349167510.0Topological domainExtracellular
HgeneDGCR2chr22:19050714chr22:19164463ENST00000537045-49369_550167510.0Topological domainCytoplasmic
HgeneDGCR2chr22:19050715chr22:19164463ENST00000263196-51021_349208551.0Topological domainExtracellular
HgeneDGCR2chr22:19050715chr22:19164463ENST00000263196-510369_550208551.0Topological domainCytoplasmic
HgeneDGCR2chr22:19050715chr22:19164463ENST00000537045-4921_349167510.0Topological domainExtracellular
HgeneDGCR2chr22:19050715chr22:19164463ENST00000537045-49369_550167510.0Topological domainCytoplasmic
HgeneDGCR2chr22:19050714chr22:19164463ENST00000263196-510350_368208551.0TransmembraneHelical
HgeneDGCR2chr22:19050714chr22:19164463ENST00000537045-49350_368167510.0TransmembraneHelical
HgeneDGCR2chr22:19050715chr22:19164463ENST00000263196-510350_368208551.0TransmembraneHelical
HgeneDGCR2chr22:19050715chr22:19164463ENST00000537045-49350_368167510.0TransmembraneHelical
TgeneSLC25A1chr22:19050714chr22:19164463ENST0000021588249122_208175312.0RepeatNote=Solcar 2
TgeneSLC25A1chr22:19050714chr22:19164463ENST000002158824923_111175312.0RepeatNote=Solcar 1
TgeneSLC25A1chr22:19050715chr22:19164463ENST0000021588249122_208175312.0RepeatNote=Solcar 2
TgeneSLC25A1chr22:19050715chr22:19164463ENST000002158824923_111175312.0RepeatNote=Solcar 1
TgeneSLC25A1chr22:19050714chr22:19164463ENST0000021588249129_143175312.0TransmembraneHelical%3B Name%3D3
TgeneSLC25A1chr22:19050714chr22:19164463ENST000002158824929_46175312.0TransmembraneHelical%3B Name%3D1
TgeneSLC25A1chr22:19050714chr22:19164463ENST000002158824986_105175312.0TransmembraneHelical%3B Name%3D2
TgeneSLC25A1chr22:19050715chr22:19164463ENST0000021588249129_143175312.0TransmembraneHelical%3B Name%3D3
TgeneSLC25A1chr22:19050715chr22:19164463ENST000002158824929_46175312.0TransmembraneHelical%3B Name%3D1
TgeneSLC25A1chr22:19050715chr22:19164463ENST000002158824986_105175312.0TransmembraneHelical%3B Name%3D2


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Fusion Gene Sequence for DGCR2-SLC25A1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>22415_22415_1_DGCR2-SLC25A1_DGCR2_chr22_19050714_ENST00000263196_SLC25A1_chr22_19164463_ENST00000215882_length(transcript)=1831nt_BP=873nt
GGGGCGGGGCGGCGCGGCGCGGAGCCGAGCAGGACGGCCGCCATCTTGCGCGCAGCTGGAGTCGGTGCCTGAGGTTGCAGCCGAGAGTGT
GCGCCAGCCCGCGGCCCAGCCGAAGCTCTTTCCCGCCGCCTCTCCGCGCCTCGCCCAGGTTCAGCTCCGCCTGACCCTCCGCTTGGCACG
GTCCCCTGACCCTCAGTCCGGCCTGGTCCGGCCTTCCAGCCGCCCCGGGGACGATGAACGGAGGATAAATGGTGCCCAAGGCAGACAGCG
GCGCCTTCCTGCTGCTCTTCCTGCTCGTGCTCACTGTCACCGAGCCGCTGCGGCCAGAGCTGCGGTGCAACCCTGGGCAGTTTGCGTGTC
GCAGCGGCACCATCCAGTGCATCCCCCTCCCCTGGCAGTGTGACGGCTGGGCGACTTGCGAGGATGAGAGCGACGAAGCCAACTGTCCAG
AAGTGACCGGGGAGGTGCGTCCTCATCATGGGAAGGAGGCTGTGGATCCGCGGCAGGGGCGGGCCAGAGGAGGCGACCCTTCGCACTTCC
ACGCGGTGAACGTGGCGCAGCCCGTTCGCTTCAGCAGTTTCCTAGGGAAGTGCCCGACAGGGTGGCACCACTACGAAGGCACGGCCAGCT
GCTACCGGGTCTACCTGAGCGGGGAGAACTACTGGGATGCCGCGCAGACCTGCCAGCGCCTGAATGGCTCTCTCGCCACCTTCTCCACTG
ACCAGGAGCTGCGCTTTGTCCTGGCCCAGGAATGGGACCAGCCCGAGCGGAGCTTTGGTTGGAAGGACCAGCGCAAGTTGTGGGTTGGCT
ATCAGTATGTTATCACTGGCCGGAACCGCTCCTTGGAAGGTCGCTGGGAGGTGGCATTCAAAGGGCTGAAGGGGACGTACCAGGGCCTCA
CAGCCACTGTCCTGAAGCAGGGCTCGAACCAGGCCATCCGCTTCTTCGTCATGACCTCCCTGCGCAACTGGTACCGAGGGGACAACCCCA
ACAAGCCCATGAACCCTCTGATCACTGGGGTCTTCGGAGCTATTGCAGGCGCAGCCAGTGTCTTTGGAAACACTCCTCTGGATGTGATTA
AGACCCGGATGCAGGGCCTGGAGGCGCACAAATACCGGAACACGTGGGACTGCGGCTTGCAGATCCTGAAGAAGGAGGGGCTCAAGGCAT
TCTACAAGGGCACTGTCCCCCGCCTGGGCCGGGTCTGCCTGGATGTGGCCATAGTGTTTGTCATCTATGATGAAGTGGTGAAGCTGCTCA
ACAAAGTGTGGAAGACGGACTAAGCCTAGAGAGGCCGCAAGGGGACCGCCCCAGGCACCGCCAGAGTGTCCTGCTACCTTTGTCTCACGA
TTCCAGTGCAGTAGTGCCAAAAGGCCCCTTCCCACGTCCCTCGAGCTCTGTAGCCTGGTCTGTGCATTGTGGCTGTCAAATCCATGTGTC
CCCCCTGTGGTCTGTGTGTGACACCACCACTGTGTCCCAGTGTCTGGCCCAGCCATGGCTGGATGTGCATCTGGCCTATGACCCTGTGCC
TGTGTTTCATGTTCTGTGTCACGTGACCCTGTGCCCCGCCTCCCGGGGTGCCCGTGTGGCCTGGGTCCTCGGCCCTGTAGCCCTGGCCCG
GTCCCAGTCCGGTGCCTTCCACCCTGCCCTGGCCTACCACAGCTGCCTCCGGGCCTCGGCCTGGCTTCACCGCATTCCAGGGGCTGCAGC
CCCCTGCTTCTCCCGCCATTGGCCTTAACTGGCCCTCGGGCCCTCTCTCCGCCCCGGACAGGGTGGCACCCACCACTCTCAGGACCACCC

>22415_22415_1_DGCR2-SLC25A1_DGCR2_chr22_19050714_ENST00000263196_SLC25A1_chr22_19164463_ENST00000215882_length(amino acids)=409AA_BP=1
MPWQGGPESGGCHPVRGGERARGPVKANGGRSRGLQPLECGEARPRPGGSCGRPGQGGRHRTGTGPGLQGRGPRPHGHPGRRGTGSRDTE
HETQAQGHRPDAHPAMAGPDTGTQWWCHTQTTGGTHGFDSHNAQTRLQSSRDVGRGLLALLHWNRETKVAGHSGGAWGGPLAASLGLVRL
PHFVEQLHHFIIDDKHYGHIQADPAQAGDSALVECLEPLLLQDLQAAVPRVPVFVRLQALHPGLNHIQRSVSKDTGCACNSSEDPSDQRV
HGLVGVVPSVPVAQGGHDEEADGLVRALLQDSGCEALVRPLQPFECHLPATFQGAVPASDNILIANPQLALVLPTKAPLGLVPFLGQDKA

--------------------------------------------------------------
>22415_22415_2_DGCR2-SLC25A1_DGCR2_chr22_19050714_ENST00000263196_SLC25A1_chr22_19164463_ENST00000451283_length(transcript)=1820nt_BP=873nt
GGGGCGGGGCGGCGCGGCGCGGAGCCGAGCAGGACGGCCGCCATCTTGCGCGCAGCTGGAGTCGGTGCCTGAGGTTGCAGCCGAGAGTGT
GCGCCAGCCCGCGGCCCAGCCGAAGCTCTTTCCCGCCGCCTCTCCGCGCCTCGCCCAGGTTCAGCTCCGCCTGACCCTCCGCTTGGCACG
GTCCCCTGACCCTCAGTCCGGCCTGGTCCGGCCTTCCAGCCGCCCCGGGGACGATGAACGGAGGATAAATGGTGCCCAAGGCAGACAGCG
GCGCCTTCCTGCTGCTCTTCCTGCTCGTGCTCACTGTCACCGAGCCGCTGCGGCCAGAGCTGCGGTGCAACCCTGGGCAGTTTGCGTGTC
GCAGCGGCACCATCCAGTGCATCCCCCTCCCCTGGCAGTGTGACGGCTGGGCGACTTGCGAGGATGAGAGCGACGAAGCCAACTGTCCAG
AAGTGACCGGGGAGGTGCGTCCTCATCATGGGAAGGAGGCTGTGGATCCGCGGCAGGGGCGGGCCAGAGGAGGCGACCCTTCGCACTTCC
ACGCGGTGAACGTGGCGCAGCCCGTTCGCTTCAGCAGTTTCCTAGGGAAGTGCCCGACAGGGTGGCACCACTACGAAGGCACGGCCAGCT
GCTACCGGGTCTACCTGAGCGGGGAGAACTACTGGGATGCCGCGCAGACCTGCCAGCGCCTGAATGGCTCTCTCGCCACCTTCTCCACTG
ACCAGGAGCTGCGCTTTGTCCTGGCCCAGGAATGGGACCAGCCCGAGCGGAGCTTTGGTTGGAAGGACCAGCGCAAGTTGTGGGTTGGCT
ATCAGTATGTTATCACTGGCCGGAACCGCTCCTTGGAAGGTCGCTGGGAGGTGGCATTCAAAGGGCTGAAGGGGACGTACCAGGGCCTCA
CAGCCACTGTCCTGAAGCAGGGCTCGAACCAGGCCATCCGCTTCTTCGTCATGACCTCCCTGCGCAACTGGTACCGAGGGGACAACCCCA
ACAAGCCCATGAACCCTCTGATCACTGGGGTCTTCGGAGCTATTGCAGGCGCAGCCAGTGTCTTTGGAAACACTCCTCTGGATGTGATTA
AGACCCGGATGCAGGGCCTGGAGGCGCACAAATACCGGAACACGTGGGACTGCGGCTTGCAGATCCTGAAGAAGGAGGGGCTCAAGGCAT
TCTACAAGGGCACTGTCCCCCGCCTGGGCCGGGTCTGCCTGGATGTGGCCATAGTGTTTGTCATCTATGATGAAGTGGTGAAGCTGCTCA
ACAAAGTGTGGAAGACGGACTAAGCCTAGAGAGGCCGCAAGGGGACCGCCCCAGGCACCGCCAGAGTGTCCTGCTACCTTTGTCTCACGA
TTCCAGTGCAGTAGTGCCAAAAGGCCCCTTCCCACGTCCCTCGAGCTCTGTAGCCTGGTCTGTGCATTGTGGCTGTCAAATCCATGTGTC
CCCCCTGTGGTCTGTGTGTGACACCACCACTGTGTCCCAGTGTCTGGCCCAGCCATGGCTGGATGTGCATCTGGCCTATGACCCTGTGCC
TGTGTTTCATGTTCTGTGTCACGTGACCCTGTGCCCCGCCTCCCGGGGTGCCCGTGTGGCCTGGGTCCTCGGCCCTGTAGCCCTGGCCCG
GTCCCAGTCCGGTGCCTTCCACCCTGCCCTGGCCTACCACAGCTGCCTCCGGGCCTCGGCCTGGCTTCACCGCATTCCAGGGGCTGCAGC
CCCCTGCTTCTCCCGCCATTGGCCTTAACTGGCCCTCGGGCCCTCTCTCCGCCCCGGACAGGGTGGCACCCACCACTCTCAGGACCACCC

>22415_22415_2_DGCR2-SLC25A1_DGCR2_chr22_19050714_ENST00000263196_SLC25A1_chr22_19164463_ENST00000451283_length(amino acids)=409AA_BP=1
MPWQGGPESGGCHPVRGGERARGPVKANGGRSRGLQPLECGEARPRPGGSCGRPGQGGRHRTGTGPGLQGRGPRPHGHPGRRGTGSRDTE
HETQAQGHRPDAHPAMAGPDTGTQWWCHTQTTGGTHGFDSHNAQTRLQSSRDVGRGLLALLHWNRETKVAGHSGGAWGGPLAASLGLVRL
PHFVEQLHHFIIDDKHYGHIQADPAQAGDSALVECLEPLLLQDLQAAVPRVPVFVRLQALHPGLNHIQRSVSKDTGCACNSSEDPSDQRV
HGLVGVVPSVPVAQGGHDEEADGLVRALLQDSGCEALVRPLQPFECHLPATFQGAVPASDNILIANPQLALVLPTKAPLGLVPFLGQDKA

--------------------------------------------------------------
>22415_22415_3_DGCR2-SLC25A1_DGCR2_chr22_19050714_ENST00000537045_SLC25A1_chr22_19164463_ENST00000215882_length(transcript)=1708nt_BP=750nt
GGGGCGGGGCGGCGCGGCGCGGAGCCGAGCAGGACGGCCGCCATCTTGCGCGCAGCTGGAGTCGGTGCCTGAGGTTGCAGCCGAGAGTGT
GCGCCAGCCCGCGGCCCAGCCGAAGCTCTTTCCCGCCGCCTCTCCGCGCCTCGCCCAGGTTCAGCTCCGCCTGACCCTCCGCTTGGCACG
GTCCCCTGACCCTCAGTCCGGCCTGGTCCGGCCTTCCAGCCGCCCCGGGGACGATGAACGGAGGATAAATGGTGCCCAAGGCAGACAGCG
GCGCCTTCCTGCTGCTCTTCCTGCTCGTGCTCACTGTCACCGAGCCGCTGCGGCCAGAAGTGACCGGGGAGGTGCGTCCTCATCATGGGA
AGGAGGCTGTGGATCCGCGGCAGGGGCGGGCCAGAGGAGGCGACCCTTCGCACTTCCACGCGGTGAACGTGGCGCAGCCCGTTCGCTTCA
GCAGTTTCCTAGGGAAGTGCCCGACAGGGTGGCACCACTACGAAGGCACGGCCAGCTGCTACCGGGTCTACCTGAGCGGGGAGAACTACT
GGGATGCCGCGCAGACCTGCCAGCGCCTGAATGGCTCTCTCGCCACCTTCTCCACTGACCAGGAGCTGCGCTTTGTCCTGGCCCAGGAAT
GGGACCAGCCCGAGCGGAGCTTTGGTTGGAAGGACCAGCGCAAGTTGTGGGTTGGCTATCAGTATGTTATCACTGGCCGGAACCGCTCCT
TGGAAGGTCGCTGGGAGGTGGCATTCAAAGGGCTGAAGGGGACGTACCAGGGCCTCACAGCCACTGTCCTGAAGCAGGGCTCGAACCAGG
CCATCCGCTTCTTCGTCATGACCTCCCTGCGCAACTGGTACCGAGGGGACAACCCCAACAAGCCCATGAACCCTCTGATCACTGGGGTCT
TCGGAGCTATTGCAGGCGCAGCCAGTGTCTTTGGAAACACTCCTCTGGATGTGATTAAGACCCGGATGCAGGGCCTGGAGGCGCACAAAT
ACCGGAACACGTGGGACTGCGGCTTGCAGATCCTGAAGAAGGAGGGGCTCAAGGCATTCTACAAGGGCACTGTCCCCCGCCTGGGCCGGG
TCTGCCTGGATGTGGCCATAGTGTTTGTCATCTATGATGAAGTGGTGAAGCTGCTCAACAAAGTGTGGAAGACGGACTAAGCCTAGAGAG
GCCGCAAGGGGACCGCCCCAGGCACCGCCAGAGTGTCCTGCTACCTTTGTCTCACGATTCCAGTGCAGTAGTGCCAAAAGGCCCCTTCCC
ACGTCCCTCGAGCTCTGTAGCCTGGTCTGTGCATTGTGGCTGTCAAATCCATGTGTCCCCCCTGTGGTCTGTGTGTGACACCACCACTGT
GTCCCAGTGTCTGGCCCAGCCATGGCTGGATGTGCATCTGGCCTATGACCCTGTGCCTGTGTTTCATGTTCTGTGTCACGTGACCCTGTG
CCCCGCCTCCCGGGGTGCCCGTGTGGCCTGGGTCCTCGGCCCTGTAGCCCTGGCCCGGTCCCAGTCCGGTGCCTTCCACCCTGCCCTGGC
CTACCACAGCTGCCTCCGGGCCTCGGCCTGGCTTCACCGCATTCCAGGGGCTGCAGCCCCCTGCTTCTCCCGCCATTGGCCTTAACTGGC

>22415_22415_3_DGCR2-SLC25A1_DGCR2_chr22_19050714_ENST00000537045_SLC25A1_chr22_19164463_ENST00000215882_length(amino acids)=409AA_BP=1
MPWQGGPESGGCHPVRGGERARGPVKANGGRSRGLQPLECGEARPRPGGSCGRPGQGGRHRTGTGPGLQGRGPRPHGHPGRRGTGSRDTE
HETQAQGHRPDAHPAMAGPDTGTQWWCHTQTTGGTHGFDSHNAQTRLQSSRDVGRGLLALLHWNRETKVAGHSGGAWGGPLAASLGLVRL
PHFVEQLHHFIIDDKHYGHIQADPAQAGDSALVECLEPLLLQDLQAAVPRVPVFVRLQALHPGLNHIQRSVSKDTGCACNSSEDPSDQRV
HGLVGVVPSVPVAQGGHDEEADGLVRALLQDSGCEALVRPLQPFECHLPATFQGAVPASDNILIANPQLALVLPTKAPLGLVPFLGQDKA

--------------------------------------------------------------
>22415_22415_4_DGCR2-SLC25A1_DGCR2_chr22_19050714_ENST00000537045_SLC25A1_chr22_19164463_ENST00000451283_length(transcript)=1697nt_BP=750nt
GGGGCGGGGCGGCGCGGCGCGGAGCCGAGCAGGACGGCCGCCATCTTGCGCGCAGCTGGAGTCGGTGCCTGAGGTTGCAGCCGAGAGTGT
GCGCCAGCCCGCGGCCCAGCCGAAGCTCTTTCCCGCCGCCTCTCCGCGCCTCGCCCAGGTTCAGCTCCGCCTGACCCTCCGCTTGGCACG
GTCCCCTGACCCTCAGTCCGGCCTGGTCCGGCCTTCCAGCCGCCCCGGGGACGATGAACGGAGGATAAATGGTGCCCAAGGCAGACAGCG
GCGCCTTCCTGCTGCTCTTCCTGCTCGTGCTCACTGTCACCGAGCCGCTGCGGCCAGAAGTGACCGGGGAGGTGCGTCCTCATCATGGGA
AGGAGGCTGTGGATCCGCGGCAGGGGCGGGCCAGAGGAGGCGACCCTTCGCACTTCCACGCGGTGAACGTGGCGCAGCCCGTTCGCTTCA
GCAGTTTCCTAGGGAAGTGCCCGACAGGGTGGCACCACTACGAAGGCACGGCCAGCTGCTACCGGGTCTACCTGAGCGGGGAGAACTACT
GGGATGCCGCGCAGACCTGCCAGCGCCTGAATGGCTCTCTCGCCACCTTCTCCACTGACCAGGAGCTGCGCTTTGTCCTGGCCCAGGAAT
GGGACCAGCCCGAGCGGAGCTTTGGTTGGAAGGACCAGCGCAAGTTGTGGGTTGGCTATCAGTATGTTATCACTGGCCGGAACCGCTCCT
TGGAAGGTCGCTGGGAGGTGGCATTCAAAGGGCTGAAGGGGACGTACCAGGGCCTCACAGCCACTGTCCTGAAGCAGGGCTCGAACCAGG
CCATCCGCTTCTTCGTCATGACCTCCCTGCGCAACTGGTACCGAGGGGACAACCCCAACAAGCCCATGAACCCTCTGATCACTGGGGTCT
TCGGAGCTATTGCAGGCGCAGCCAGTGTCTTTGGAAACACTCCTCTGGATGTGATTAAGACCCGGATGCAGGGCCTGGAGGCGCACAAAT
ACCGGAACACGTGGGACTGCGGCTTGCAGATCCTGAAGAAGGAGGGGCTCAAGGCATTCTACAAGGGCACTGTCCCCCGCCTGGGCCGGG
TCTGCCTGGATGTGGCCATAGTGTTTGTCATCTATGATGAAGTGGTGAAGCTGCTCAACAAAGTGTGGAAGACGGACTAAGCCTAGAGAG
GCCGCAAGGGGACCGCCCCAGGCACCGCCAGAGTGTCCTGCTACCTTTGTCTCACGATTCCAGTGCAGTAGTGCCAAAAGGCCCCTTCCC
ACGTCCCTCGAGCTCTGTAGCCTGGTCTGTGCATTGTGGCTGTCAAATCCATGTGTCCCCCCTGTGGTCTGTGTGTGACACCACCACTGT
GTCCCAGTGTCTGGCCCAGCCATGGCTGGATGTGCATCTGGCCTATGACCCTGTGCCTGTGTTTCATGTTCTGTGTCACGTGACCCTGTG
CCCCGCCTCCCGGGGTGCCCGTGTGGCCTGGGTCCTCGGCCCTGTAGCCCTGGCCCGGTCCCAGTCCGGTGCCTTCCACCCTGCCCTGGC
CTACCACAGCTGCCTCCGGGCCTCGGCCTGGCTTCACCGCATTCCAGGGGCTGCAGCCCCCTGCTTCTCCCGCCATTGGCCTTAACTGGC

>22415_22415_4_DGCR2-SLC25A1_DGCR2_chr22_19050714_ENST00000537045_SLC25A1_chr22_19164463_ENST00000451283_length(amino acids)=409AA_BP=1
MPWQGGPESGGCHPVRGGERARGPVKANGGRSRGLQPLECGEARPRPGGSCGRPGQGGRHRTGTGPGLQGRGPRPHGHPGRRGTGSRDTE
HETQAQGHRPDAHPAMAGPDTGTQWWCHTQTTGGTHGFDSHNAQTRLQSSRDVGRGLLALLHWNRETKVAGHSGGAWGGPLAASLGLVRL
PHFVEQLHHFIIDDKHYGHIQADPAQAGDSALVECLEPLLLQDLQAAVPRVPVFVRLQALHPGLNHIQRSVSKDTGCACNSSEDPSDQRV
HGLVGVVPSVPVAQGGHDEEADGLVRALLQDSGCEALVRPLQPFECHLPATFQGAVPASDNILIANPQLALVLPTKAPLGLVPFLGQDKA

--------------------------------------------------------------
>22415_22415_5_DGCR2-SLC25A1_DGCR2_chr22_19050715_ENST00000263196_SLC25A1_chr22_19164463_ENST00000215882_length(transcript)=1831nt_BP=873nt
GGGGCGGGGCGGCGCGGCGCGGAGCCGAGCAGGACGGCCGCCATCTTGCGCGCAGCTGGAGTCGGTGCCTGAGGTTGCAGCCGAGAGTGT
GCGCCAGCCCGCGGCCCAGCCGAAGCTCTTTCCCGCCGCCTCTCCGCGCCTCGCCCAGGTTCAGCTCCGCCTGACCCTCCGCTTGGCACG
GTCCCCTGACCCTCAGTCCGGCCTGGTCCGGCCTTCCAGCCGCCCCGGGGACGATGAACGGAGGATAAATGGTGCCCAAGGCAGACAGCG
GCGCCTTCCTGCTGCTCTTCCTGCTCGTGCTCACTGTCACCGAGCCGCTGCGGCCAGAGCTGCGGTGCAACCCTGGGCAGTTTGCGTGTC
GCAGCGGCACCATCCAGTGCATCCCCCTCCCCTGGCAGTGTGACGGCTGGGCGACTTGCGAGGATGAGAGCGACGAAGCCAACTGTCCAG
AAGTGACCGGGGAGGTGCGTCCTCATCATGGGAAGGAGGCTGTGGATCCGCGGCAGGGGCGGGCCAGAGGAGGCGACCCTTCGCACTTCC
ACGCGGTGAACGTGGCGCAGCCCGTTCGCTTCAGCAGTTTCCTAGGGAAGTGCCCGACAGGGTGGCACCACTACGAAGGCACGGCCAGCT
GCTACCGGGTCTACCTGAGCGGGGAGAACTACTGGGATGCCGCGCAGACCTGCCAGCGCCTGAATGGCTCTCTCGCCACCTTCTCCACTG
ACCAGGAGCTGCGCTTTGTCCTGGCCCAGGAATGGGACCAGCCCGAGCGGAGCTTTGGTTGGAAGGACCAGCGCAAGTTGTGGGTTGGCT
ATCAGTATGTTATCACTGGCCGGAACCGCTCCTTGGAAGGTCGCTGGGAGGTGGCATTCAAAGGGCTGAAGGGGACGTACCAGGGCCTCA
CAGCCACTGTCCTGAAGCAGGGCTCGAACCAGGCCATCCGCTTCTTCGTCATGACCTCCCTGCGCAACTGGTACCGAGGGGACAACCCCA
ACAAGCCCATGAACCCTCTGATCACTGGGGTCTTCGGAGCTATTGCAGGCGCAGCCAGTGTCTTTGGAAACACTCCTCTGGATGTGATTA
AGACCCGGATGCAGGGCCTGGAGGCGCACAAATACCGGAACACGTGGGACTGCGGCTTGCAGATCCTGAAGAAGGAGGGGCTCAAGGCAT
TCTACAAGGGCACTGTCCCCCGCCTGGGCCGGGTCTGCCTGGATGTGGCCATAGTGTTTGTCATCTATGATGAAGTGGTGAAGCTGCTCA
ACAAAGTGTGGAAGACGGACTAAGCCTAGAGAGGCCGCAAGGGGACCGCCCCAGGCACCGCCAGAGTGTCCTGCTACCTTTGTCTCACGA
TTCCAGTGCAGTAGTGCCAAAAGGCCCCTTCCCACGTCCCTCGAGCTCTGTAGCCTGGTCTGTGCATTGTGGCTGTCAAATCCATGTGTC
CCCCCTGTGGTCTGTGTGTGACACCACCACTGTGTCCCAGTGTCTGGCCCAGCCATGGCTGGATGTGCATCTGGCCTATGACCCTGTGCC
TGTGTTTCATGTTCTGTGTCACGTGACCCTGTGCCCCGCCTCCCGGGGTGCCCGTGTGGCCTGGGTCCTCGGCCCTGTAGCCCTGGCCCG
GTCCCAGTCCGGTGCCTTCCACCCTGCCCTGGCCTACCACAGCTGCCTCCGGGCCTCGGCCTGGCTTCACCGCATTCCAGGGGCTGCAGC
CCCCTGCTTCTCCCGCCATTGGCCTTAACTGGCCCTCGGGCCCTCTCTCCGCCCCGGACAGGGTGGCACCCACCACTCTCAGGACCACCC

>22415_22415_5_DGCR2-SLC25A1_DGCR2_chr22_19050715_ENST00000263196_SLC25A1_chr22_19164463_ENST00000215882_length(amino acids)=409AA_BP=1
MPWQGGPESGGCHPVRGGERARGPVKANGGRSRGLQPLECGEARPRPGGSCGRPGQGGRHRTGTGPGLQGRGPRPHGHPGRRGTGSRDTE
HETQAQGHRPDAHPAMAGPDTGTQWWCHTQTTGGTHGFDSHNAQTRLQSSRDVGRGLLALLHWNRETKVAGHSGGAWGGPLAASLGLVRL
PHFVEQLHHFIIDDKHYGHIQADPAQAGDSALVECLEPLLLQDLQAAVPRVPVFVRLQALHPGLNHIQRSVSKDTGCACNSSEDPSDQRV
HGLVGVVPSVPVAQGGHDEEADGLVRALLQDSGCEALVRPLQPFECHLPATFQGAVPASDNILIANPQLALVLPTKAPLGLVPFLGQDKA

--------------------------------------------------------------
>22415_22415_6_DGCR2-SLC25A1_DGCR2_chr22_19050715_ENST00000263196_SLC25A1_chr22_19164463_ENST00000451283_length(transcript)=1820nt_BP=873nt
GGGGCGGGGCGGCGCGGCGCGGAGCCGAGCAGGACGGCCGCCATCTTGCGCGCAGCTGGAGTCGGTGCCTGAGGTTGCAGCCGAGAGTGT
GCGCCAGCCCGCGGCCCAGCCGAAGCTCTTTCCCGCCGCCTCTCCGCGCCTCGCCCAGGTTCAGCTCCGCCTGACCCTCCGCTTGGCACG
GTCCCCTGACCCTCAGTCCGGCCTGGTCCGGCCTTCCAGCCGCCCCGGGGACGATGAACGGAGGATAAATGGTGCCCAAGGCAGACAGCG
GCGCCTTCCTGCTGCTCTTCCTGCTCGTGCTCACTGTCACCGAGCCGCTGCGGCCAGAGCTGCGGTGCAACCCTGGGCAGTTTGCGTGTC
GCAGCGGCACCATCCAGTGCATCCCCCTCCCCTGGCAGTGTGACGGCTGGGCGACTTGCGAGGATGAGAGCGACGAAGCCAACTGTCCAG
AAGTGACCGGGGAGGTGCGTCCTCATCATGGGAAGGAGGCTGTGGATCCGCGGCAGGGGCGGGCCAGAGGAGGCGACCCTTCGCACTTCC
ACGCGGTGAACGTGGCGCAGCCCGTTCGCTTCAGCAGTTTCCTAGGGAAGTGCCCGACAGGGTGGCACCACTACGAAGGCACGGCCAGCT
GCTACCGGGTCTACCTGAGCGGGGAGAACTACTGGGATGCCGCGCAGACCTGCCAGCGCCTGAATGGCTCTCTCGCCACCTTCTCCACTG
ACCAGGAGCTGCGCTTTGTCCTGGCCCAGGAATGGGACCAGCCCGAGCGGAGCTTTGGTTGGAAGGACCAGCGCAAGTTGTGGGTTGGCT
ATCAGTATGTTATCACTGGCCGGAACCGCTCCTTGGAAGGTCGCTGGGAGGTGGCATTCAAAGGGCTGAAGGGGACGTACCAGGGCCTCA
CAGCCACTGTCCTGAAGCAGGGCTCGAACCAGGCCATCCGCTTCTTCGTCATGACCTCCCTGCGCAACTGGTACCGAGGGGACAACCCCA
ACAAGCCCATGAACCCTCTGATCACTGGGGTCTTCGGAGCTATTGCAGGCGCAGCCAGTGTCTTTGGAAACACTCCTCTGGATGTGATTA
AGACCCGGATGCAGGGCCTGGAGGCGCACAAATACCGGAACACGTGGGACTGCGGCTTGCAGATCCTGAAGAAGGAGGGGCTCAAGGCAT
TCTACAAGGGCACTGTCCCCCGCCTGGGCCGGGTCTGCCTGGATGTGGCCATAGTGTTTGTCATCTATGATGAAGTGGTGAAGCTGCTCA
ACAAAGTGTGGAAGACGGACTAAGCCTAGAGAGGCCGCAAGGGGACCGCCCCAGGCACCGCCAGAGTGTCCTGCTACCTTTGTCTCACGA
TTCCAGTGCAGTAGTGCCAAAAGGCCCCTTCCCACGTCCCTCGAGCTCTGTAGCCTGGTCTGTGCATTGTGGCTGTCAAATCCATGTGTC
CCCCCTGTGGTCTGTGTGTGACACCACCACTGTGTCCCAGTGTCTGGCCCAGCCATGGCTGGATGTGCATCTGGCCTATGACCCTGTGCC
TGTGTTTCATGTTCTGTGTCACGTGACCCTGTGCCCCGCCTCCCGGGGTGCCCGTGTGGCCTGGGTCCTCGGCCCTGTAGCCCTGGCCCG
GTCCCAGTCCGGTGCCTTCCACCCTGCCCTGGCCTACCACAGCTGCCTCCGGGCCTCGGCCTGGCTTCACCGCATTCCAGGGGCTGCAGC
CCCCTGCTTCTCCCGCCATTGGCCTTAACTGGCCCTCGGGCCCTCTCTCCGCCCCGGACAGGGTGGCACCCACCACTCTCAGGACCACCC

>22415_22415_6_DGCR2-SLC25A1_DGCR2_chr22_19050715_ENST00000263196_SLC25A1_chr22_19164463_ENST00000451283_length(amino acids)=409AA_BP=1
MPWQGGPESGGCHPVRGGERARGPVKANGGRSRGLQPLECGEARPRPGGSCGRPGQGGRHRTGTGPGLQGRGPRPHGHPGRRGTGSRDTE
HETQAQGHRPDAHPAMAGPDTGTQWWCHTQTTGGTHGFDSHNAQTRLQSSRDVGRGLLALLHWNRETKVAGHSGGAWGGPLAASLGLVRL
PHFVEQLHHFIIDDKHYGHIQADPAQAGDSALVECLEPLLLQDLQAAVPRVPVFVRLQALHPGLNHIQRSVSKDTGCACNSSEDPSDQRV
HGLVGVVPSVPVAQGGHDEEADGLVRALLQDSGCEALVRPLQPFECHLPATFQGAVPASDNILIANPQLALVLPTKAPLGLVPFLGQDKA

--------------------------------------------------------------
>22415_22415_7_DGCR2-SLC25A1_DGCR2_chr22_19050715_ENST00000537045_SLC25A1_chr22_19164463_ENST00000215882_length(transcript)=1708nt_BP=750nt
GGGGCGGGGCGGCGCGGCGCGGAGCCGAGCAGGACGGCCGCCATCTTGCGCGCAGCTGGAGTCGGTGCCTGAGGTTGCAGCCGAGAGTGT
GCGCCAGCCCGCGGCCCAGCCGAAGCTCTTTCCCGCCGCCTCTCCGCGCCTCGCCCAGGTTCAGCTCCGCCTGACCCTCCGCTTGGCACG
GTCCCCTGACCCTCAGTCCGGCCTGGTCCGGCCTTCCAGCCGCCCCGGGGACGATGAACGGAGGATAAATGGTGCCCAAGGCAGACAGCG
GCGCCTTCCTGCTGCTCTTCCTGCTCGTGCTCACTGTCACCGAGCCGCTGCGGCCAGAAGTGACCGGGGAGGTGCGTCCTCATCATGGGA
AGGAGGCTGTGGATCCGCGGCAGGGGCGGGCCAGAGGAGGCGACCCTTCGCACTTCCACGCGGTGAACGTGGCGCAGCCCGTTCGCTTCA
GCAGTTTCCTAGGGAAGTGCCCGACAGGGTGGCACCACTACGAAGGCACGGCCAGCTGCTACCGGGTCTACCTGAGCGGGGAGAACTACT
GGGATGCCGCGCAGACCTGCCAGCGCCTGAATGGCTCTCTCGCCACCTTCTCCACTGACCAGGAGCTGCGCTTTGTCCTGGCCCAGGAAT
GGGACCAGCCCGAGCGGAGCTTTGGTTGGAAGGACCAGCGCAAGTTGTGGGTTGGCTATCAGTATGTTATCACTGGCCGGAACCGCTCCT
TGGAAGGTCGCTGGGAGGTGGCATTCAAAGGGCTGAAGGGGACGTACCAGGGCCTCACAGCCACTGTCCTGAAGCAGGGCTCGAACCAGG
CCATCCGCTTCTTCGTCATGACCTCCCTGCGCAACTGGTACCGAGGGGACAACCCCAACAAGCCCATGAACCCTCTGATCACTGGGGTCT
TCGGAGCTATTGCAGGCGCAGCCAGTGTCTTTGGAAACACTCCTCTGGATGTGATTAAGACCCGGATGCAGGGCCTGGAGGCGCACAAAT
ACCGGAACACGTGGGACTGCGGCTTGCAGATCCTGAAGAAGGAGGGGCTCAAGGCATTCTACAAGGGCACTGTCCCCCGCCTGGGCCGGG
TCTGCCTGGATGTGGCCATAGTGTTTGTCATCTATGATGAAGTGGTGAAGCTGCTCAACAAAGTGTGGAAGACGGACTAAGCCTAGAGAG
GCCGCAAGGGGACCGCCCCAGGCACCGCCAGAGTGTCCTGCTACCTTTGTCTCACGATTCCAGTGCAGTAGTGCCAAAAGGCCCCTTCCC
ACGTCCCTCGAGCTCTGTAGCCTGGTCTGTGCATTGTGGCTGTCAAATCCATGTGTCCCCCCTGTGGTCTGTGTGTGACACCACCACTGT
GTCCCAGTGTCTGGCCCAGCCATGGCTGGATGTGCATCTGGCCTATGACCCTGTGCCTGTGTTTCATGTTCTGTGTCACGTGACCCTGTG
CCCCGCCTCCCGGGGTGCCCGTGTGGCCTGGGTCCTCGGCCCTGTAGCCCTGGCCCGGTCCCAGTCCGGTGCCTTCCACCCTGCCCTGGC
CTACCACAGCTGCCTCCGGGCCTCGGCCTGGCTTCACCGCATTCCAGGGGCTGCAGCCCCCTGCTTCTCCCGCCATTGGCCTTAACTGGC

>22415_22415_7_DGCR2-SLC25A1_DGCR2_chr22_19050715_ENST00000537045_SLC25A1_chr22_19164463_ENST00000215882_length(amino acids)=409AA_BP=1
MPWQGGPESGGCHPVRGGERARGPVKANGGRSRGLQPLECGEARPRPGGSCGRPGQGGRHRTGTGPGLQGRGPRPHGHPGRRGTGSRDTE
HETQAQGHRPDAHPAMAGPDTGTQWWCHTQTTGGTHGFDSHNAQTRLQSSRDVGRGLLALLHWNRETKVAGHSGGAWGGPLAASLGLVRL
PHFVEQLHHFIIDDKHYGHIQADPAQAGDSALVECLEPLLLQDLQAAVPRVPVFVRLQALHPGLNHIQRSVSKDTGCACNSSEDPSDQRV
HGLVGVVPSVPVAQGGHDEEADGLVRALLQDSGCEALVRPLQPFECHLPATFQGAVPASDNILIANPQLALVLPTKAPLGLVPFLGQDKA

--------------------------------------------------------------
>22415_22415_8_DGCR2-SLC25A1_DGCR2_chr22_19050715_ENST00000537045_SLC25A1_chr22_19164463_ENST00000451283_length(transcript)=1697nt_BP=750nt
GGGGCGGGGCGGCGCGGCGCGGAGCCGAGCAGGACGGCCGCCATCTTGCGCGCAGCTGGAGTCGGTGCCTGAGGTTGCAGCCGAGAGTGT
GCGCCAGCCCGCGGCCCAGCCGAAGCTCTTTCCCGCCGCCTCTCCGCGCCTCGCCCAGGTTCAGCTCCGCCTGACCCTCCGCTTGGCACG
GTCCCCTGACCCTCAGTCCGGCCTGGTCCGGCCTTCCAGCCGCCCCGGGGACGATGAACGGAGGATAAATGGTGCCCAAGGCAGACAGCG
GCGCCTTCCTGCTGCTCTTCCTGCTCGTGCTCACTGTCACCGAGCCGCTGCGGCCAGAAGTGACCGGGGAGGTGCGTCCTCATCATGGGA
AGGAGGCTGTGGATCCGCGGCAGGGGCGGGCCAGAGGAGGCGACCCTTCGCACTTCCACGCGGTGAACGTGGCGCAGCCCGTTCGCTTCA
GCAGTTTCCTAGGGAAGTGCCCGACAGGGTGGCACCACTACGAAGGCACGGCCAGCTGCTACCGGGTCTACCTGAGCGGGGAGAACTACT
GGGATGCCGCGCAGACCTGCCAGCGCCTGAATGGCTCTCTCGCCACCTTCTCCACTGACCAGGAGCTGCGCTTTGTCCTGGCCCAGGAAT
GGGACCAGCCCGAGCGGAGCTTTGGTTGGAAGGACCAGCGCAAGTTGTGGGTTGGCTATCAGTATGTTATCACTGGCCGGAACCGCTCCT
TGGAAGGTCGCTGGGAGGTGGCATTCAAAGGGCTGAAGGGGACGTACCAGGGCCTCACAGCCACTGTCCTGAAGCAGGGCTCGAACCAGG
CCATCCGCTTCTTCGTCATGACCTCCCTGCGCAACTGGTACCGAGGGGACAACCCCAACAAGCCCATGAACCCTCTGATCACTGGGGTCT
TCGGAGCTATTGCAGGCGCAGCCAGTGTCTTTGGAAACACTCCTCTGGATGTGATTAAGACCCGGATGCAGGGCCTGGAGGCGCACAAAT
ACCGGAACACGTGGGACTGCGGCTTGCAGATCCTGAAGAAGGAGGGGCTCAAGGCATTCTACAAGGGCACTGTCCCCCGCCTGGGCCGGG
TCTGCCTGGATGTGGCCATAGTGTTTGTCATCTATGATGAAGTGGTGAAGCTGCTCAACAAAGTGTGGAAGACGGACTAAGCCTAGAGAG
GCCGCAAGGGGACCGCCCCAGGCACCGCCAGAGTGTCCTGCTACCTTTGTCTCACGATTCCAGTGCAGTAGTGCCAAAAGGCCCCTTCCC
ACGTCCCTCGAGCTCTGTAGCCTGGTCTGTGCATTGTGGCTGTCAAATCCATGTGTCCCCCCTGTGGTCTGTGTGTGACACCACCACTGT
GTCCCAGTGTCTGGCCCAGCCATGGCTGGATGTGCATCTGGCCTATGACCCTGTGCCTGTGTTTCATGTTCTGTGTCACGTGACCCTGTG
CCCCGCCTCCCGGGGTGCCCGTGTGGCCTGGGTCCTCGGCCCTGTAGCCCTGGCCCGGTCCCAGTCCGGTGCCTTCCACCCTGCCCTGGC
CTACCACAGCTGCCTCCGGGCCTCGGCCTGGCTTCACCGCATTCCAGGGGCTGCAGCCCCCTGCTTCTCCCGCCATTGGCCTTAACTGGC

>22415_22415_8_DGCR2-SLC25A1_DGCR2_chr22_19050715_ENST00000537045_SLC25A1_chr22_19164463_ENST00000451283_length(amino acids)=409AA_BP=1
MPWQGGPESGGCHPVRGGERARGPVKANGGRSRGLQPLECGEARPRPGGSCGRPGQGGRHRTGTGPGLQGRGPRPHGHPGRRGTGSRDTE
HETQAQGHRPDAHPAMAGPDTGTQWWCHTQTTGGTHGFDSHNAQTRLQSSRDVGRGLLALLHWNRETKVAGHSGGAWGGPLAASLGLVRL
PHFVEQLHHFIIDDKHYGHIQADPAQAGDSALVECLEPLLLQDLQAAVPRVPVFVRLQALHPGLNHIQRSVSKDTGCACNSSEDPSDQRV
HGLVGVVPSVPVAQGGHDEEADGLVRALLQDSGCEALVRPLQPFECHLPATFQGAVPASDNILIANPQLALVLPTKAPLGLVPFLGQDKA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for DGCR2-SLC25A1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DGCR2-SLC25A1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DGCR2-SLC25A1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource