FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:DGKA-DSG1 (FusionGDB2 ID:22431)

Fusion Gene Summary for DGKA-DSG1

check button Fusion gene summary
Fusion gene informationFusion gene name: DGKA-DSG1
Fusion gene ID: 22431
HgeneTgene
Gene symbol

DGKA

DSG1

Gene ID

1606

1828

Gene namediacylglycerol kinase alphadesmoglein 1
SynonymsDAGK|DAGK1|DGK-alphaCDHF4|DG1|DSG|EPKHE|EPKHIA|PPKS1|SPPK1
Cytomap

12q13.2

18q12.1

Type of geneprotein-codingprotein-coding
Descriptiondiacylglycerol kinase alpha80 kDa diacylglycerol kinaseDAG kinase alphadiacylglycerol kinase, alpha 80kDadiglyceride kinase alphadesmoglein-1cadherin family member 4desmosomal glycoprotein 1pemphigus foliaceus antigen
Modification date2020031320200313
UniProtAcc

P23743

Q02413

Ensembl transtripts involved in fusion geneENST00000549079, ENST00000331886, 
ENST00000394147, ENST00000551156, 
ENST00000257192, ENST00000462981, 
Fusion gene scores* DoF score6 X 6 X 2=723 X 5 X 3=45
# samples 75
** MAII scorelog2(7/72*10)=-0.0406419844973459
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/45*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: DGKA [Title/Abstract] AND DSG1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDGKA(56334217)-DSG1(28908152), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneDGKA

GO:0006654

phosphatidic acid biosynthetic process

22627129

HgeneDGKA

GO:0046339

diacylglycerol metabolic process

22627129

HgeneDGKA

GO:0046486

glycerolipid metabolic process

22627129

HgeneDGKA

GO:0046834

lipid phosphorylation

18004883|22627129

TgeneDSG1

GO:0050821

protein stabilization

7983064


check buttonFusion gene breakpoints across DGKA (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DSG1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-VQ-A922-01ADGKAchr12

56334217

+DSG1chr18

28908152

+
ChimerDB4STADTCGA-VQ-A922DGKAchr12

56334217

+DSG1chr18

28908151

+


Top

Fusion Gene ORF analysis for DGKA-DSG1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000549079ENST00000257192DGKAchr12

56334217

+DSG1chr18

28908152

+
3UTR-3CDSENST00000549079ENST00000257192DGKAchr12

56334217

+DSG1chr18

28908151

+
3UTR-intronENST00000549079ENST00000462981DGKAchr12

56334217

+DSG1chr18

28908152

+
3UTR-intronENST00000549079ENST00000462981DGKAchr12

56334217

+DSG1chr18

28908151

+
5CDS-intronENST00000331886ENST00000462981DGKAchr12

56334217

+DSG1chr18

28908152

+
5CDS-intronENST00000331886ENST00000462981DGKAchr12

56334217

+DSG1chr18

28908151

+
5CDS-intronENST00000394147ENST00000462981DGKAchr12

56334217

+DSG1chr18

28908152

+
5CDS-intronENST00000394147ENST00000462981DGKAchr12

56334217

+DSG1chr18

28908151

+
5CDS-intronENST00000551156ENST00000462981DGKAchr12

56334217

+DSG1chr18

28908152

+
5CDS-intronENST00000551156ENST00000462981DGKAchr12

56334217

+DSG1chr18

28908151

+
In-frameENST00000331886ENST00000257192DGKAchr12

56334217

+DSG1chr18

28908152

+
In-frameENST00000331886ENST00000257192DGKAchr12

56334217

+DSG1chr18

28908151

+
In-frameENST00000394147ENST00000257192DGKAchr12

56334217

+DSG1chr18

28908152

+
In-frameENST00000394147ENST00000257192DGKAchr12

56334217

+DSG1chr18

28908151

+
In-frameENST00000551156ENST00000257192DGKAchr12

56334217

+DSG1chr18

28908152

+
In-frameENST00000551156ENST00000257192DGKAchr12

56334217

+DSG1chr18

28908151

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000331886DGKAchr1256334217+ENST00000257192DSG1chr1828908152+5989137233443051323
ENST00000394147DGKAchr1256334217+ENST00000257192DSG1chr1828908152+5844122721941601313
ENST00000551156DGKAchr1256334217+ENST00000257192DSG1chr1828908152+573911223940551338
ENST00000331886DGKAchr1256334217+ENST00000257192DSG1chr1828908151+5989137233443051323
ENST00000394147DGKAchr1256334217+ENST00000257192DSG1chr1828908151+5844122721941601313
ENST00000551156DGKAchr1256334217+ENST00000257192DSG1chr1828908151+573911223940551338

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000331886ENST00000257192DGKAchr1256334217+DSG1chr1828908152+0.0001560380.99984396
ENST00000394147ENST00000257192DGKAchr1256334217+DSG1chr1828908152+0.0001360450.999864
ENST00000551156ENST00000257192DGKAchr1256334217+DSG1chr1828908152+0.0001195110.99988043
ENST00000331886ENST00000257192DGKAchr1256334217+DSG1chr1828908151+0.0001560380.99984396
ENST00000394147ENST00000257192DGKAchr1256334217+DSG1chr1828908151+0.0001360450.999864
ENST00000551156ENST00000257192DGKAchr1256334217+DSG1chr1828908151+0.0001195110.99988043

Top

Fusion Genomic Features for DGKA-DSG1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DGKAchr1256334217+DSG1chr1828908151+0.0006334290.9993666
DGKAchr1256334217+DSG1chr1828908151+0.0006334290.9993666
DGKAchr1256334217+DSG1chr1828908151+0.0006334290.9993666
DGKAchr1256334217+DSG1chr1828908151+0.0006334290.9993666

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for DGKA-DSG1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:56334217/chr18:28908152)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DGKA

P23743

DSG1

Q02413

FUNCTION: Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids (PubMed:2175712, PubMed:15544348). Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (PubMed:2175712, PubMed:15544348). Also plays an important role in the biosynthesis of complex lipids (Probable). Can also phosphorylate 1-alkyl-2-acylglycerol in vitro as efficiently as diacylglycerol provided it contains an arachidonoyl group (PubMed:15544348). Also involved in the production of alkyl-lysophosphatidic acid, another bioactive lipid, through the phosphorylation of 1-alkyl-2-acetyl glycerol (PubMed:22627129). {ECO:0000269|PubMed:15544348, ECO:0000269|PubMed:2175712, ECO:0000269|PubMed:22627129, ECO:0000305}.FUNCTION: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDGKAchr12:56334217chr18:28908151ENST00000331886+1124123_134306736.0Calcium binding1
HgeneDGKAchr12:56334217chr18:28908151ENST00000331886+1124168_179306736.0Calcium binding2
HgeneDGKAchr12:56334217chr18:28908151ENST00000394147+1124123_134306736.0Calcium binding1
HgeneDGKAchr12:56334217chr18:28908151ENST00000394147+1124168_179306736.0Calcium binding2
HgeneDGKAchr12:56334217chr18:28908151ENST00000551156+1124123_134306736.0Calcium binding1
HgeneDGKAchr12:56334217chr18:28908151ENST00000551156+1124168_179306736.0Calcium binding2
HgeneDGKAchr12:56334217chr18:28908152ENST00000331886+1124123_134306736.0Calcium binding1
HgeneDGKAchr12:56334217chr18:28908152ENST00000331886+1124168_179306736.0Calcium binding2
HgeneDGKAchr12:56334217chr18:28908152ENST00000394147+1124123_134306736.0Calcium binding1
HgeneDGKAchr12:56334217chr18:28908152ENST00000394147+1124168_179306736.0Calcium binding2
HgeneDGKAchr12:56334217chr18:28908152ENST00000551156+1124123_134306736.0Calcium binding1
HgeneDGKAchr12:56334217chr18:28908152ENST00000551156+1124168_179306736.0Calcium binding2
HgeneDGKAchr12:56334217chr18:28908151ENST00000331886+1124110_145306736.0DomainEF-hand 1
HgeneDGKAchr12:56334217chr18:28908151ENST00000331886+1124155_190306736.0DomainEF-hand 2
HgeneDGKAchr12:56334217chr18:28908151ENST00000394147+1124110_145306736.0DomainEF-hand 1
HgeneDGKAchr12:56334217chr18:28908151ENST00000394147+1124155_190306736.0DomainEF-hand 2
HgeneDGKAchr12:56334217chr18:28908151ENST00000551156+1124110_145306736.0DomainEF-hand 1
HgeneDGKAchr12:56334217chr18:28908151ENST00000551156+1124155_190306736.0DomainEF-hand 2
HgeneDGKAchr12:56334217chr18:28908152ENST00000331886+1124110_145306736.0DomainEF-hand 1
HgeneDGKAchr12:56334217chr18:28908152ENST00000331886+1124155_190306736.0DomainEF-hand 2
HgeneDGKAchr12:56334217chr18:28908152ENST00000394147+1124110_145306736.0DomainEF-hand 1
HgeneDGKAchr12:56334217chr18:28908152ENST00000394147+1124155_190306736.0DomainEF-hand 2
HgeneDGKAchr12:56334217chr18:28908152ENST00000551156+1124110_145306736.0DomainEF-hand 1
HgeneDGKAchr12:56334217chr18:28908152ENST00000551156+1124155_190306736.0DomainEF-hand 2
HgeneDGKAchr12:56334217chr18:28908151ENST00000331886+1124205_253306736.0Zinc fingerPhorbol-ester/DAG-type 1
HgeneDGKAchr12:56334217chr18:28908151ENST00000394147+1124205_253306736.0Zinc fingerPhorbol-ester/DAG-type 1
HgeneDGKAchr12:56334217chr18:28908151ENST00000551156+1124205_253306736.0Zinc fingerPhorbol-ester/DAG-type 1
HgeneDGKAchr12:56334217chr18:28908152ENST00000331886+1124205_253306736.0Zinc fingerPhorbol-ester/DAG-type 1
HgeneDGKAchr12:56334217chr18:28908152ENST00000394147+1124205_253306736.0Zinc fingerPhorbol-ester/DAG-type 1
HgeneDGKAchr12:56334217chr18:28908152ENST00000551156+1124205_253306736.0Zinc fingerPhorbol-ester/DAG-type 1
TgeneDSG1chr12:56334217chr18:28908151ENST00000257192215969_1019721050.0Compositional biasNote=Gly/Ser-rich
TgeneDSG1chr12:56334217chr18:28908152ENST00000257192215969_1019721050.0Compositional biasNote=Gly/Ser-rich
TgeneDSG1chr12:56334217chr18:28908151ENST00000257192215159_270721050.0DomainCadherin 2
TgeneDSG1chr12:56334217chr18:28908151ENST00000257192215271_385721050.0DomainCadherin 3
TgeneDSG1chr12:56334217chr18:28908151ENST00000257192215386_497721050.0DomainCadherin 4
TgeneDSG1chr12:56334217chr18:28908152ENST00000257192215159_270721050.0DomainCadherin 2
TgeneDSG1chr12:56334217chr18:28908152ENST00000257192215271_385721050.0DomainCadherin 3
TgeneDSG1chr12:56334217chr18:28908152ENST00000257192215386_497721050.0DomainCadherin 4
TgeneDSG1chr12:56334217chr18:28908151ENST00000257192215813_839721050.0RepeatNote=Desmoglein repeat 1
TgeneDSG1chr12:56334217chr18:28908151ENST00000257192215840_869721050.0RepeatNote=Desmoglein repeat 2
TgeneDSG1chr12:56334217chr18:28908151ENST00000257192215870_899721050.0RepeatNote=Desmoglein repeat 3
TgeneDSG1chr12:56334217chr18:28908151ENST00000257192215900_927721050.0RepeatNote=Desmoglein repeat 4
TgeneDSG1chr12:56334217chr18:28908151ENST00000257192215928_956721050.0RepeatNote=Desmoglein repeat 5
TgeneDSG1chr12:56334217chr18:28908152ENST00000257192215813_839721050.0RepeatNote=Desmoglein repeat 1
TgeneDSG1chr12:56334217chr18:28908152ENST00000257192215840_869721050.0RepeatNote=Desmoglein repeat 2
TgeneDSG1chr12:56334217chr18:28908152ENST00000257192215870_899721050.0RepeatNote=Desmoglein repeat 3
TgeneDSG1chr12:56334217chr18:28908152ENST00000257192215900_927721050.0RepeatNote=Desmoglein repeat 4
TgeneDSG1chr12:56334217chr18:28908152ENST00000257192215928_956721050.0RepeatNote=Desmoglein repeat 5
TgeneDSG1chr12:56334217chr18:28908151ENST00000257192215570_1049721050.0Topological domainCytoplasmic
TgeneDSG1chr12:56334217chr18:28908152ENST00000257192215570_1049721050.0Topological domainCytoplasmic
TgeneDSG1chr12:56334217chr18:28908151ENST00000257192215549_569721050.0TransmembraneHelical
TgeneDSG1chr12:56334217chr18:28908152ENST00000257192215549_569721050.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDGKAchr12:56334217chr18:28908151ENST00000331886+1124372_506306736.0DomainDAGKc
HgeneDGKAchr12:56334217chr18:28908151ENST00000394147+1124372_506306736.0DomainDAGKc
HgeneDGKAchr12:56334217chr18:28908151ENST00000551156+1124372_506306736.0DomainDAGKc
HgeneDGKAchr12:56334217chr18:28908152ENST00000331886+1124372_506306736.0DomainDAGKc
HgeneDGKAchr12:56334217chr18:28908152ENST00000394147+1124372_506306736.0DomainDAGKc
HgeneDGKAchr12:56334217chr18:28908152ENST00000551156+1124372_506306736.0DomainDAGKc
HgeneDGKAchr12:56334217chr18:28908151ENST00000331886+1124269_319306736.0Zinc fingerPhorbol-ester/DAG-type 2
HgeneDGKAchr12:56334217chr18:28908151ENST00000394147+1124269_319306736.0Zinc fingerPhorbol-ester/DAG-type 2
HgeneDGKAchr12:56334217chr18:28908151ENST00000551156+1124269_319306736.0Zinc fingerPhorbol-ester/DAG-type 2
HgeneDGKAchr12:56334217chr18:28908152ENST00000331886+1124269_319306736.0Zinc fingerPhorbol-ester/DAG-type 2
HgeneDGKAchr12:56334217chr18:28908152ENST00000394147+1124269_319306736.0Zinc fingerPhorbol-ester/DAG-type 2
HgeneDGKAchr12:56334217chr18:28908152ENST00000551156+1124269_319306736.0Zinc fingerPhorbol-ester/DAG-type 2
TgeneDSG1chr12:56334217chr18:28908151ENST0000025719221550_158721050.0DomainCadherin 1
TgeneDSG1chr12:56334217chr18:28908152ENST0000025719221550_158721050.0DomainCadherin 1
TgeneDSG1chr12:56334217chr18:28908151ENST0000025719221550_548721050.0Topological domainExtracellular
TgeneDSG1chr12:56334217chr18:28908152ENST0000025719221550_548721050.0Topological domainExtracellular


Top

Fusion Gene Sequence for DGKA-DSG1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>22431_22431_1_DGKA-DSG1_DGKA_chr12_56334217_ENST00000331886_DSG1_chr18_28908151_ENST00000257192_length(transcript)=5989nt_BP=1372nt
ACACAATACCCACACATGCATATACCCTTCTAGTCAGAGGTCTCCCCTCCCCCTTCTTCCCACCCCCAGGTGTAAGAAGGACGATTCCAG
GAACCTAAGGCTTTGTTACTCTGCCCCATTTTCAATGAAGGGTAGGAGGGAGTTAGACAGGGGTTGGGGCGGGGCCAGTGAGCAGGATGC
CTGGGTCTCCAGTTCCTGCCAGTGAGTCCCTAGGCCTCCATCTCTCTCCCTTGCTGTACCACCTTCACCACCATCCATGCGACCCCAAGA
GCCTTAATGACTCTAGAAGAGACTCCAGGCAGGGGAAGCTGAAAGGACCTTTCACTCCCTACTTTTGGCCAGGGCCTTCTGTGCCACCTG
CCAAGACCAGCAGGCCTACCCTCTGAAGAGGTCCAAGCAACGGAAGTACTACTACGAAGCTGCCTTTCTGGCCATCCTTGAGAAAAATAG
ACAGATGGCCAAGGAGAGGGGCCTAATAAGCCCCAGTGATTTTGCCCAGCTGCAAAAATACATGGAATACTCCACCAAAAAGGTCAGTGA
TGTCCTAAAGCTCTTCGAGGATGGCGAGATGGCTAAATATGTCCAAGGAGATGCCATTGGGTACGAGGGATTCCAGCAATTCCTGAAAAT
CTATCTCGAAGTGGATAATGTTCCCAGACACCTAAGCCTGGCACTGTTTCAATCCTTTGAGACTGGTCACTGCTTAAATGAGACAAATGT
GACAAAAGATGTGGTGTGTCTCAATGATGTTTCCTGCTACTTTTCCCTTCTGGAGGGTGGTCGGCCAGAAGACAAGTTAGAATTCACCTT
CAAGCTGTACGACACGGACAGAAATGGGATCCTGGACAGCTCAGAAGTGGACAAAATTATCCTACAGATGATGCGAGTGGCTGAATACCT
GGATTGGGATGTGTCTGAGCTGAGGCCGATTCTTCAGGAGATGATGAAAGAGATTGACTATGATGGCAGTGGCTCTGTCTCTCAAGCTGA
GTGGGTCCGGGCTGGGGCCACCACCGTGCCACTGCTAGTGCTGCTGGGTCTGGAGATGACTCTGAAGGACGACGGACAGCACATGTGGAG
GCCCAAGAGGTTCCCCAGACCAGTCTACTGCAATCTGTGCGAGTCAAGCATTGGTCTTGGCAAACAGGGACTGAGCTGTAACCTCTGTAA
GTACACTGTTCACGACCAGTGTGCCATGAAAGCCCTGCCTTGTGAAGTCAGCACCTATGCCAAGTCTCGGAAGGACATTGGTGTCCAATC
ACATGTGTGGGTGCGAGGAGGCTGTGAGTCCGGGCGCTGCGACCGCTGTCAGAAAAAGATCCGGATCTACCACAGTCTGACCGGGCTGCA
TTGTGTATGGTGCCACCTAGAGATTCACTCAGATTGTGCTGCAAACCAGCAAGTTACATACCGCATCTCTGGAGTAGGAATTGATCAGCC
ACCATATGGGATCTTTGTCATTAATCAGAAAACTGGTGAAATTAATATAACATCCATAGTTGATCGAGAGGTCACTCCTTTCTTCATTAT
CTACTGCCGAGCTCTGAACTCAATGGGCCAAGATTTAGAGAGGCCTCTAGAGCTCAGAGTCAGGGTTTTGGATATAAATGACAACCCTCC
AGTGTTTTCAATGGCTACATTTGCAGGACAAATAGAAGAAAATTCTAATGCAAATACACTGGTGATGATACTCAATGCTACTGACGCAGA
TGAACCGAACAATTTGAACTCAAAAATAGCCTTCAAGATTATAAGACAAGAACCTTCAGATTCACCAATGTTTATTATCAACAGAAATAC
TGGAGAAATTCGAACGATGAATAATTTTCTAGACAGAGAGCAATACGGCCAGTATGCTCTTGCTGTAAGAGGCTCTGACCGAGATGGCGG
GGCAGATGGCATGTCAGCGGAATGTGAGTGCAACATTAAAATCCTCGATGTCAATGATAATATCCCTTACATGGAACAGTCTTCATATAC
CATAGAAATTCAAGAAAATACTCTAAATTCAAATTTGCTCGAGATTAGAGTAATTGATTTGGATGAAGAGTTCTCAGCTAACTGGATGGC
AGTAATTTTCTTTATCTCTGGAAATGAAGGAAATTGGTTTGAGATAGAAATGAATGAAAGAACAAATGTGGGAATTTTAAAGGTTGTTAA
GCCCTTAGATTATGAAGCTATGCAGAGTCTGCAACTCAGTATTGGTGTCAGAAATAAAGCTGAATTTCATCATTCAATTATGTCTCAATA
TAAACTGAAAGCATCTGCAATTTCTGTGACTGTGTTAAATGTAATTGAAGGCCCAGTGTTTCGTCCAGGTTCAAAGACATATGTTGTAAC
TGGTAATATGGGATCAAATGATAAAGTGGGAGACTTTGTAGCTACTGACCTGGACACAGGTAGACCTTCAACGACTGTTAGGTATGTAAT
GGGAAATAATCCAGCTGACCTGCTAGCTGTTGATTCAAGAACAGGCAAACTCACTTTGAAAAATAAAGTTACCAAGGAACAGTACAATAT
GCTCGGAGGAAAATACCAAGGAACGATTCTCTCTATAGATGATAATCTTCAAAGAACTTGCACTGGTACAATTAATATTAACATTCAAAG
TTTTGGTAATGACGACAGGACTAATACAGAGCCGAACACTAAAATTACTACCAATACTGGCAGACAAGAAAGTACTTCTTCCACTAACTA
TGATACCAGCACAACTTCTACTGACTCTAGCCAAGTATATTCTTCTGAACCCGGAAACGGAGCCAAAGATTTGTTATCAGACAATGTACA
TTTTGGTCCTGCTGGCATTGGACTCCTCATCATGGGATTCTTGGTCTTAGGATTGGTCCCATTTTTGATGATCTGTTGTGATTGTGGAGG
TGCTCCTCGTAGTGCAGCTGGCTTTGAGCCTGTTCCCGAATGTTCAGATGGAGCAATTCATTCATGGGCAGTAGAAGGACCACAGCCTGA
ACCCAGGGATATAACCACTGTCATACCACAAATACCACCTGATAACGCAAATATAATTGAATGCATTGACAACTCAGGAGTTTATACAAA
TGAGTATGGTGGCAGAGAAATGCAAGATCTGGGAGGAGGAGAGAGAATGACAGGATTTGAACTAACAGAGGGAGTTAAAACTTCAGGAAT
GCCTGAGATATGTCAAGAATACTCTGGAACATTAAGAAGAAATTCTATGAGGGAATGTAGAGAAGGAGGTCTGAATATGAATTTCATGGA
AAGCTACTTCTGTCAGAAAGCATATGCTTACGCAGATGAAGATGAAGGACGCCCATCTAATGACTGTTTGCTCATATATGACATCGAAGG
TGTAGGTTCCCCTGCTGGCTCTGTGGGTTGTTGTAGCTTCATTGGAGAAGACCTGGATGACAGCTTCTTGGATACCCTGGGACCTAAATT
TAAGAAGTTGGCAGACATCAGCCTAGGAAAAGAATCATATCCAGACCTTGATCCTTCTTGGCCACCACAAAGCACTGAACCAGTTTGCCT
TCCTCAGGAAACAGAGCCCGTTGTTAGTGGACACCCACCAATCTCCCCACATTTCGGCACTACCACAGTAATTTCTGAGAGCACCTATCC
CTCGGGACCTGGTGTACTGCATCCTAAGCCTATTCTCGATCCTCTGGGCTATGGTAATGTCACTGTGACCGAGTCTTACACCACCTCTGA
CACTCTGAAGCCCTCTGTGCACGTTCACGATAACCGACCAGCATCAAACGTGGTAGTGACAGAGAGAGTGGTCGGCCCAATCTCTGGCGC
TGATTTGCATGGAATGTTAGAGATGCCTGACTTGCGAGATGGGTCGAATGTTATAGTGACAGAAAGGGTAATAGCACCAAGCTCTAGTCT
ACCCACCTCTCTGACTATCCATCATCCTAGAGAGTCTTCAAATGTGGTAGTGACAGAAAGAGTAATCCAACCAACTTCCGGCATGATAGG
TAGTCTGAGTATGCACCCCGAGTTAGCCAATGCCCACAATGTCATTGTGACAGAGAGGGTTGTTTCTGGTGCTGGCGTAACTGGAATTAG
TGGCACCACTGGGATCAGCGGTGGCATAGGCAGCAGTGGCCTGGTTGGCACCAGCATGGGTGCTGGGAGCGGTGCCCTGAGTGGAGCTGG
CATAAGTGGTGGTGGCATTGGCCTGAGCAGCTTGGGAGGGACAGCCAGCATTGGCCACATGAGGAGTTCCTCTGACCATCACTTTAACCA
AACCATTGGGTCCGCCTCCCCTAGCACAGCTCGAAGTCGAATCACAAAGTATAGTACCGTGCAATATAGCAAGTAGTCAGGACCCCAGCT
CACTTTTTCATAGTCATTGTGGTTTAGATCCAATTCCCACCACTAAAAAACCAACAATGTGATTTATAACGCACAACTTCGTGCTCAGGT
CATCTAGGAGCAAGGTGAGAAATCACAATGAGAAAAATAAATGGAAACACCACTGCTAGGGGAGAGCTCTCCTTAGCATTCATAAACTTT
TCTCTTATATTAGGACTAAGGAACTAAAACTTGAGGCAGAGTCTTCTTTGTGCCTGAGTGGCCTGTAGTCCATCTCCAGCATGTAACTGG
CCTTACGATGGCAATTGGCATCATTCTCCTTGCTCTGTTTTGCTTTTCCATATAGCTCGAGCAAAATTCAAAAAGAACTAAATATGCAAT
ATATGTTCATATCTATGGGAAAAATCTAAAATGTGTGCCAGATGCCCTGTTGGTTTCACAGATAACATAAATAAAAATTCAACCACAGAT
TTATACAAGGGTTAACCATTTTTTTTAAGTTTGACTACATAGTCAAGTCCACAAGCCATCAAGCACTCCTACCTTAATTATTGCACTAGA
GAAAATAAATTCCAAATTAGGAAGTGTTTCCTAGGAGGAAAATTCCATTAGAGAGTGGCAATAGGATGAGGTTTCTTCAGGGTAAACTAG
CAATGCCTGAGCCTGAACCTTAATGTGGGGCCTCAGTTAAATCTCCTGTGGAGTCAAGGATTCTTCTGATTCTAGTGTGTGTTTAGTGAT
AGATGTAGTCTTGACGAATATTGCTTACTGGTGAGGTTGAGGAATATCACACTCGTCTTTCCCTTTACCACTGTGGTTTTGACTTAAGAA
AGCAAAACTCACTAAGTTTACTTCTCGAATTGAAGCAAGTGAGGCCTGACATGGTTGTCATCACTAGTGGCAAATGACCTTCCAAGTAAG
CAGATGGGAACTGAATTGTGTTTTCAGGTTTTGTTTTTAGTAGGTGATATTCATTCGTATCCAGCTCTTTATTACATAGCTCTGAAGTTA
AAATGATTTACATAGGCCGAGCTGTGGACAAAAAAAAAAGAAGCAGCAGCTTGTAGTATGCTTAAGCTTTGGGGAATTTTTTTTTAAGGG
GATCTAAAAAAATGTTTTTAGAACATGTAAAATGTTTAATGGTGAAAGTTGGAAAAGAATTCTTCTGTAAAGTAATACCATGCTAATTAT
TCGCTTTTAGTAAGTAAAGTAGTGGTTGCTTTAGCAAACCTCTGCTGCCATTTTGCAGGAATCAACCAGGAACCTTTAGCAGAATTGACA
ATATGGTGTTGATAAGCATGAAATAATAATAGAAACCTATTCTGCTAGTTTATCTCACCCTCTAATTTTTCTCACTAGCATAAATTTTAA
ATTCCTGATTTGATTTGTCAATAAGATCTTGGCTTATATATGCTGATTTATAGGTAGTGTCCAAATTATATAGTATAACATATTTTTCTA
GTTTCAAAATTTAGTAATGTCCTATTTATGATATATCATTTCTGTGTGTTTGCTATGTAGTATTACCCAATTAAAAATCTCTAAAAAGAA
TTAAAGCATTCTAAGAAAAAGGTAAATTTACTATTGCATGGTACAGAAATTTTTTCTTTCTTAAATACAATGTTACTATAAGCTCACTAA

>22431_22431_1_DGKA-DSG1_DGKA_chr12_56334217_ENST00000331886_DSG1_chr18_28908151_ENST00000257192_length(amino acids)=1323AA_BP=344
MARAFCATCQDQQAYPLKRSKQRKYYYEAAFLAILEKNRQMAKERGLISPSDFAQLQKYMEYSTKKVSDVLKLFEDGEMAKYVQGDAIGY
EGFQQFLKIYLEVDNVPRHLSLALFQSFETGHCLNETNVTKDVVCLNDVSCYFSLLEGGRPEDKLEFTFKLYDTDRNGILDSSEVDKIIL
QMMRVAEYLDWDVSELRPILQEMMKEIDYDGSGSVSQAEWVRAGATTVPLLVLLGLEMTLKDDGQHMWRPKRFPRPVYCNLCESSIGLGK
QGLSCNLCKYTVHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIRIYHSLTGLHCVWCHLEIHSDCAANQQVTYR
ISGVGIDQPPYGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLV
MILNATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRDGGADGMSAECECNIKILDVNDNI
PYMEQSSYTIEIQENTLNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAE
FHHSIMSQYKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTGKLTLKN
KVTKEQYNMLGGKYQGTILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTSTDSSQVYSSEPGNGA
KDLLSDNVHFGPAGIGLLIMGFLVLGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSWAVEGPQPEPRDITTVIPQIPPDNANIIEC
IDNSGVYTNEYGGREMQDLGGGERMTGFELTEGVKTSGMPEICQEYSGTLRRNSMRECREGGLNMNFMESYFCQKAYAYADEDEGRPSND
CLLIYDIEGVGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLGKESYPDLDPSWPPQSTEPVCLPQETEPVVSGHPPISPHFGTT
TVISESTYPSGPGVLHPKPILDPLGYGNVTVTESYTTSDTLKPSVHVHDNRPASNVVVTERVVGPISGADLHGMLEMPDLRDGSNVIVTE
RVIAPSSSLPTSLTIHHPRESSNVVVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVSGAGVTGISGTTGISGGIGSSGLVGTSMGA

--------------------------------------------------------------
>22431_22431_2_DGKA-DSG1_DGKA_chr12_56334217_ENST00000331886_DSG1_chr18_28908152_ENST00000257192_length(transcript)=5989nt_BP=1372nt
ACACAATACCCACACATGCATATACCCTTCTAGTCAGAGGTCTCCCCTCCCCCTTCTTCCCACCCCCAGGTGTAAGAAGGACGATTCCAG
GAACCTAAGGCTTTGTTACTCTGCCCCATTTTCAATGAAGGGTAGGAGGGAGTTAGACAGGGGTTGGGGCGGGGCCAGTGAGCAGGATGC
CTGGGTCTCCAGTTCCTGCCAGTGAGTCCCTAGGCCTCCATCTCTCTCCCTTGCTGTACCACCTTCACCACCATCCATGCGACCCCAAGA
GCCTTAATGACTCTAGAAGAGACTCCAGGCAGGGGAAGCTGAAAGGACCTTTCACTCCCTACTTTTGGCCAGGGCCTTCTGTGCCACCTG
CCAAGACCAGCAGGCCTACCCTCTGAAGAGGTCCAAGCAACGGAAGTACTACTACGAAGCTGCCTTTCTGGCCATCCTTGAGAAAAATAG
ACAGATGGCCAAGGAGAGGGGCCTAATAAGCCCCAGTGATTTTGCCCAGCTGCAAAAATACATGGAATACTCCACCAAAAAGGTCAGTGA
TGTCCTAAAGCTCTTCGAGGATGGCGAGATGGCTAAATATGTCCAAGGAGATGCCATTGGGTACGAGGGATTCCAGCAATTCCTGAAAAT
CTATCTCGAAGTGGATAATGTTCCCAGACACCTAAGCCTGGCACTGTTTCAATCCTTTGAGACTGGTCACTGCTTAAATGAGACAAATGT
GACAAAAGATGTGGTGTGTCTCAATGATGTTTCCTGCTACTTTTCCCTTCTGGAGGGTGGTCGGCCAGAAGACAAGTTAGAATTCACCTT
CAAGCTGTACGACACGGACAGAAATGGGATCCTGGACAGCTCAGAAGTGGACAAAATTATCCTACAGATGATGCGAGTGGCTGAATACCT
GGATTGGGATGTGTCTGAGCTGAGGCCGATTCTTCAGGAGATGATGAAAGAGATTGACTATGATGGCAGTGGCTCTGTCTCTCAAGCTGA
GTGGGTCCGGGCTGGGGCCACCACCGTGCCACTGCTAGTGCTGCTGGGTCTGGAGATGACTCTGAAGGACGACGGACAGCACATGTGGAG
GCCCAAGAGGTTCCCCAGACCAGTCTACTGCAATCTGTGCGAGTCAAGCATTGGTCTTGGCAAACAGGGACTGAGCTGTAACCTCTGTAA
GTACACTGTTCACGACCAGTGTGCCATGAAAGCCCTGCCTTGTGAAGTCAGCACCTATGCCAAGTCTCGGAAGGACATTGGTGTCCAATC
ACATGTGTGGGTGCGAGGAGGCTGTGAGTCCGGGCGCTGCGACCGCTGTCAGAAAAAGATCCGGATCTACCACAGTCTGACCGGGCTGCA
TTGTGTATGGTGCCACCTAGAGATTCACTCAGATTGTGCTGCAAACCAGCAAGTTACATACCGCATCTCTGGAGTAGGAATTGATCAGCC
ACCATATGGGATCTTTGTCATTAATCAGAAAACTGGTGAAATTAATATAACATCCATAGTTGATCGAGAGGTCACTCCTTTCTTCATTAT
CTACTGCCGAGCTCTGAACTCAATGGGCCAAGATTTAGAGAGGCCTCTAGAGCTCAGAGTCAGGGTTTTGGATATAAATGACAACCCTCC
AGTGTTTTCAATGGCTACATTTGCAGGACAAATAGAAGAAAATTCTAATGCAAATACACTGGTGATGATACTCAATGCTACTGACGCAGA
TGAACCGAACAATTTGAACTCAAAAATAGCCTTCAAGATTATAAGACAAGAACCTTCAGATTCACCAATGTTTATTATCAACAGAAATAC
TGGAGAAATTCGAACGATGAATAATTTTCTAGACAGAGAGCAATACGGCCAGTATGCTCTTGCTGTAAGAGGCTCTGACCGAGATGGCGG
GGCAGATGGCATGTCAGCGGAATGTGAGTGCAACATTAAAATCCTCGATGTCAATGATAATATCCCTTACATGGAACAGTCTTCATATAC
CATAGAAATTCAAGAAAATACTCTAAATTCAAATTTGCTCGAGATTAGAGTAATTGATTTGGATGAAGAGTTCTCAGCTAACTGGATGGC
AGTAATTTTCTTTATCTCTGGAAATGAAGGAAATTGGTTTGAGATAGAAATGAATGAAAGAACAAATGTGGGAATTTTAAAGGTTGTTAA
GCCCTTAGATTATGAAGCTATGCAGAGTCTGCAACTCAGTATTGGTGTCAGAAATAAAGCTGAATTTCATCATTCAATTATGTCTCAATA
TAAACTGAAAGCATCTGCAATTTCTGTGACTGTGTTAAATGTAATTGAAGGCCCAGTGTTTCGTCCAGGTTCAAAGACATATGTTGTAAC
TGGTAATATGGGATCAAATGATAAAGTGGGAGACTTTGTAGCTACTGACCTGGACACAGGTAGACCTTCAACGACTGTTAGGTATGTAAT
GGGAAATAATCCAGCTGACCTGCTAGCTGTTGATTCAAGAACAGGCAAACTCACTTTGAAAAATAAAGTTACCAAGGAACAGTACAATAT
GCTCGGAGGAAAATACCAAGGAACGATTCTCTCTATAGATGATAATCTTCAAAGAACTTGCACTGGTACAATTAATATTAACATTCAAAG
TTTTGGTAATGACGACAGGACTAATACAGAGCCGAACACTAAAATTACTACCAATACTGGCAGACAAGAAAGTACTTCTTCCACTAACTA
TGATACCAGCACAACTTCTACTGACTCTAGCCAAGTATATTCTTCTGAACCCGGAAACGGAGCCAAAGATTTGTTATCAGACAATGTACA
TTTTGGTCCTGCTGGCATTGGACTCCTCATCATGGGATTCTTGGTCTTAGGATTGGTCCCATTTTTGATGATCTGTTGTGATTGTGGAGG
TGCTCCTCGTAGTGCAGCTGGCTTTGAGCCTGTTCCCGAATGTTCAGATGGAGCAATTCATTCATGGGCAGTAGAAGGACCACAGCCTGA
ACCCAGGGATATAACCACTGTCATACCACAAATACCACCTGATAACGCAAATATAATTGAATGCATTGACAACTCAGGAGTTTATACAAA
TGAGTATGGTGGCAGAGAAATGCAAGATCTGGGAGGAGGAGAGAGAATGACAGGATTTGAACTAACAGAGGGAGTTAAAACTTCAGGAAT
GCCTGAGATATGTCAAGAATACTCTGGAACATTAAGAAGAAATTCTATGAGGGAATGTAGAGAAGGAGGTCTGAATATGAATTTCATGGA
AAGCTACTTCTGTCAGAAAGCATATGCTTACGCAGATGAAGATGAAGGACGCCCATCTAATGACTGTTTGCTCATATATGACATCGAAGG
TGTAGGTTCCCCTGCTGGCTCTGTGGGTTGTTGTAGCTTCATTGGAGAAGACCTGGATGACAGCTTCTTGGATACCCTGGGACCTAAATT
TAAGAAGTTGGCAGACATCAGCCTAGGAAAAGAATCATATCCAGACCTTGATCCTTCTTGGCCACCACAAAGCACTGAACCAGTTTGCCT
TCCTCAGGAAACAGAGCCCGTTGTTAGTGGACACCCACCAATCTCCCCACATTTCGGCACTACCACAGTAATTTCTGAGAGCACCTATCC
CTCGGGACCTGGTGTACTGCATCCTAAGCCTATTCTCGATCCTCTGGGCTATGGTAATGTCACTGTGACCGAGTCTTACACCACCTCTGA
CACTCTGAAGCCCTCTGTGCACGTTCACGATAACCGACCAGCATCAAACGTGGTAGTGACAGAGAGAGTGGTCGGCCCAATCTCTGGCGC
TGATTTGCATGGAATGTTAGAGATGCCTGACTTGCGAGATGGGTCGAATGTTATAGTGACAGAAAGGGTAATAGCACCAAGCTCTAGTCT
ACCCACCTCTCTGACTATCCATCATCCTAGAGAGTCTTCAAATGTGGTAGTGACAGAAAGAGTAATCCAACCAACTTCCGGCATGATAGG
TAGTCTGAGTATGCACCCCGAGTTAGCCAATGCCCACAATGTCATTGTGACAGAGAGGGTTGTTTCTGGTGCTGGCGTAACTGGAATTAG
TGGCACCACTGGGATCAGCGGTGGCATAGGCAGCAGTGGCCTGGTTGGCACCAGCATGGGTGCTGGGAGCGGTGCCCTGAGTGGAGCTGG
CATAAGTGGTGGTGGCATTGGCCTGAGCAGCTTGGGAGGGACAGCCAGCATTGGCCACATGAGGAGTTCCTCTGACCATCACTTTAACCA
AACCATTGGGTCCGCCTCCCCTAGCACAGCTCGAAGTCGAATCACAAAGTATAGTACCGTGCAATATAGCAAGTAGTCAGGACCCCAGCT
CACTTTTTCATAGTCATTGTGGTTTAGATCCAATTCCCACCACTAAAAAACCAACAATGTGATTTATAACGCACAACTTCGTGCTCAGGT
CATCTAGGAGCAAGGTGAGAAATCACAATGAGAAAAATAAATGGAAACACCACTGCTAGGGGAGAGCTCTCCTTAGCATTCATAAACTTT
TCTCTTATATTAGGACTAAGGAACTAAAACTTGAGGCAGAGTCTTCTTTGTGCCTGAGTGGCCTGTAGTCCATCTCCAGCATGTAACTGG
CCTTACGATGGCAATTGGCATCATTCTCCTTGCTCTGTTTTGCTTTTCCATATAGCTCGAGCAAAATTCAAAAAGAACTAAATATGCAAT
ATATGTTCATATCTATGGGAAAAATCTAAAATGTGTGCCAGATGCCCTGTTGGTTTCACAGATAACATAAATAAAAATTCAACCACAGAT
TTATACAAGGGTTAACCATTTTTTTTAAGTTTGACTACATAGTCAAGTCCACAAGCCATCAAGCACTCCTACCTTAATTATTGCACTAGA
GAAAATAAATTCCAAATTAGGAAGTGTTTCCTAGGAGGAAAATTCCATTAGAGAGTGGCAATAGGATGAGGTTTCTTCAGGGTAAACTAG
CAATGCCTGAGCCTGAACCTTAATGTGGGGCCTCAGTTAAATCTCCTGTGGAGTCAAGGATTCTTCTGATTCTAGTGTGTGTTTAGTGAT
AGATGTAGTCTTGACGAATATTGCTTACTGGTGAGGTTGAGGAATATCACACTCGTCTTTCCCTTTACCACTGTGGTTTTGACTTAAGAA
AGCAAAACTCACTAAGTTTACTTCTCGAATTGAAGCAAGTGAGGCCTGACATGGTTGTCATCACTAGTGGCAAATGACCTTCCAAGTAAG
CAGATGGGAACTGAATTGTGTTTTCAGGTTTTGTTTTTAGTAGGTGATATTCATTCGTATCCAGCTCTTTATTACATAGCTCTGAAGTTA
AAATGATTTACATAGGCCGAGCTGTGGACAAAAAAAAAAGAAGCAGCAGCTTGTAGTATGCTTAAGCTTTGGGGAATTTTTTTTTAAGGG
GATCTAAAAAAATGTTTTTAGAACATGTAAAATGTTTAATGGTGAAAGTTGGAAAAGAATTCTTCTGTAAAGTAATACCATGCTAATTAT
TCGCTTTTAGTAAGTAAAGTAGTGGTTGCTTTAGCAAACCTCTGCTGCCATTTTGCAGGAATCAACCAGGAACCTTTAGCAGAATTGACA
ATATGGTGTTGATAAGCATGAAATAATAATAGAAACCTATTCTGCTAGTTTATCTCACCCTCTAATTTTTCTCACTAGCATAAATTTTAA
ATTCCTGATTTGATTTGTCAATAAGATCTTGGCTTATATATGCTGATTTATAGGTAGTGTCCAAATTATATAGTATAACATATTTTTCTA
GTTTCAAAATTTAGTAATGTCCTATTTATGATATATCATTTCTGTGTGTTTGCTATGTAGTATTACCCAATTAAAAATCTCTAAAAAGAA
TTAAAGCATTCTAAGAAAAAGGTAAATTTACTATTGCATGGTACAGAAATTTTTTCTTTCTTAAATACAATGTTACTATAAGCTCACTAA

>22431_22431_2_DGKA-DSG1_DGKA_chr12_56334217_ENST00000331886_DSG1_chr18_28908152_ENST00000257192_length(amino acids)=1323AA_BP=344
MARAFCATCQDQQAYPLKRSKQRKYYYEAAFLAILEKNRQMAKERGLISPSDFAQLQKYMEYSTKKVSDVLKLFEDGEMAKYVQGDAIGY
EGFQQFLKIYLEVDNVPRHLSLALFQSFETGHCLNETNVTKDVVCLNDVSCYFSLLEGGRPEDKLEFTFKLYDTDRNGILDSSEVDKIIL
QMMRVAEYLDWDVSELRPILQEMMKEIDYDGSGSVSQAEWVRAGATTVPLLVLLGLEMTLKDDGQHMWRPKRFPRPVYCNLCESSIGLGK
QGLSCNLCKYTVHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIRIYHSLTGLHCVWCHLEIHSDCAANQQVTYR
ISGVGIDQPPYGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLV
MILNATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRDGGADGMSAECECNIKILDVNDNI
PYMEQSSYTIEIQENTLNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAE
FHHSIMSQYKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTGKLTLKN
KVTKEQYNMLGGKYQGTILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTSTDSSQVYSSEPGNGA
KDLLSDNVHFGPAGIGLLIMGFLVLGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSWAVEGPQPEPRDITTVIPQIPPDNANIIEC
IDNSGVYTNEYGGREMQDLGGGERMTGFELTEGVKTSGMPEICQEYSGTLRRNSMRECREGGLNMNFMESYFCQKAYAYADEDEGRPSND
CLLIYDIEGVGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLGKESYPDLDPSWPPQSTEPVCLPQETEPVVSGHPPISPHFGTT
TVISESTYPSGPGVLHPKPILDPLGYGNVTVTESYTTSDTLKPSVHVHDNRPASNVVVTERVVGPISGADLHGMLEMPDLRDGSNVIVTE
RVIAPSSSLPTSLTIHHPRESSNVVVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVSGAGVTGISGTTGISGGIGSSGLVGTSMGA

--------------------------------------------------------------
>22431_22431_3_DGKA-DSG1_DGKA_chr12_56334217_ENST00000394147_DSG1_chr18_28908151_ENST00000257192_length(transcript)=5844nt_BP=1227nt
GCGGCCGCGTCTGCCTGGCCCGTCCCCTCCAGCCCAGCTCGGGCTCCAGCTCCAGCGCCGGCGCTTCAGCTGCGACCGCGAGCCCTCTCA
AGCAAGGTAGAGACCCCGCGAGCCCCCCAGCGCCCCACCCTCCCCCATCGGAAAAGGACAGGGGTAGGGAAGCCGAGGACCCACGGGCTG
CGTTCGTGCTGCTGGGTCGGGAAGGAGGAAGCGTGACAGCTGGAGCGGGCCTACCCTCTGAAGAGGTCCAAGCAACGGAAGTACTACTAC
GAAGCTGCCTTTCTGGCCATCCTTGAGAAAAATAGACAGATGGCCAAGGAGAGGGGCCTAATAAGCCCCAGTGATTTTGCCCAGCTGCAA
AAATACATGGAATACTCCACCAAAAAGGTCAGTGATGTCCTAAAGCTCTTCGAGGATGGCGAGATGGCTAAATATGTCCAAGGAGATGCC
ATTGGGTACGAGGGATTCCAGCAATTCCTGAAAATCTATCTCGAAGTGGATAATGTTCCCAGACACCTAAGCCTGGCACTGTTTCAATCC
TTTGAGACTGGTCACTGCTTAAATGAGACAAATGTGACAAAAGATGTGGTGTGTCTCAATGATGTTTCCTGCTACTTTTCCCTTCTGGAG
GGTGGTCGGCCAGAAGACAAGTTAGAATTCACCTTCAAGCTGTACGACACGGACAGAAATGGGATCCTGGACAGCTCAGAAGTGGACAAA
ATTATCCTACAGATGATGCGAGTGGCTGAATACCTGGATTGGGATGTGTCTGAGCTGAGGCCGATTCTTCAGGAGATGATGAAAGAGATT
GACTATGATGGCAGTGGCTCTGTCTCTCAAGCTGAGTGGGTCCGGGCTGGGGCCACCACCGTGCCACTGCTAGTGCTGCTGGGTCTGGAG
ATGACTCTGAAGGACGACGGACAGCACATGTGGAGGCCCAAGAGGTTCCCCAGACCAGTCTACTGCAATCTGTGCGAGTCAAGCATTGGT
CTTGGCAAACAGGGACTGAGCTGTAACCTCTGTAAGTACACTGTTCACGACCAGTGTGCCATGAAAGCCCTGCCTTGTGAAGTCAGCACC
TATGCCAAGTCTCGGAAGGACATTGGTGTCCAATCACATGTGTGGGTGCGAGGAGGCTGTGAGTCCGGGCGCTGCGACCGCTGTCAGAAA
AAGATCCGGATCTACCACAGTCTGACCGGGCTGCATTGTGTATGGTGCCACCTAGAGATTCACTCAGATTGTGCTGCAAACCAGCAAGTT
ACATACCGCATCTCTGGAGTAGGAATTGATCAGCCACCATATGGGATCTTTGTCATTAATCAGAAAACTGGTGAAATTAATATAACATCC
ATAGTTGATCGAGAGGTCACTCCTTTCTTCATTATCTACTGCCGAGCTCTGAACTCAATGGGCCAAGATTTAGAGAGGCCTCTAGAGCTC
AGAGTCAGGGTTTTGGATATAAATGACAACCCTCCAGTGTTTTCAATGGCTACATTTGCAGGACAAATAGAAGAAAATTCTAATGCAAAT
ACACTGGTGATGATACTCAATGCTACTGACGCAGATGAACCGAACAATTTGAACTCAAAAATAGCCTTCAAGATTATAAGACAAGAACCT
TCAGATTCACCAATGTTTATTATCAACAGAAATACTGGAGAAATTCGAACGATGAATAATTTTCTAGACAGAGAGCAATACGGCCAGTAT
GCTCTTGCTGTAAGAGGCTCTGACCGAGATGGCGGGGCAGATGGCATGTCAGCGGAATGTGAGTGCAACATTAAAATCCTCGATGTCAAT
GATAATATCCCTTACATGGAACAGTCTTCATATACCATAGAAATTCAAGAAAATACTCTAAATTCAAATTTGCTCGAGATTAGAGTAATT
GATTTGGATGAAGAGTTCTCAGCTAACTGGATGGCAGTAATTTTCTTTATCTCTGGAAATGAAGGAAATTGGTTTGAGATAGAAATGAAT
GAAAGAACAAATGTGGGAATTTTAAAGGTTGTTAAGCCCTTAGATTATGAAGCTATGCAGAGTCTGCAACTCAGTATTGGTGTCAGAAAT
AAAGCTGAATTTCATCATTCAATTATGTCTCAATATAAACTGAAAGCATCTGCAATTTCTGTGACTGTGTTAAATGTAATTGAAGGCCCA
GTGTTTCGTCCAGGTTCAAAGACATATGTTGTAACTGGTAATATGGGATCAAATGATAAAGTGGGAGACTTTGTAGCTACTGACCTGGAC
ACAGGTAGACCTTCAACGACTGTTAGGTATGTAATGGGAAATAATCCAGCTGACCTGCTAGCTGTTGATTCAAGAACAGGCAAACTCACT
TTGAAAAATAAAGTTACCAAGGAACAGTACAATATGCTCGGAGGAAAATACCAAGGAACGATTCTCTCTATAGATGATAATCTTCAAAGA
ACTTGCACTGGTACAATTAATATTAACATTCAAAGTTTTGGTAATGACGACAGGACTAATACAGAGCCGAACACTAAAATTACTACCAAT
ACTGGCAGACAAGAAAGTACTTCTTCCACTAACTATGATACCAGCACAACTTCTACTGACTCTAGCCAAGTATATTCTTCTGAACCCGGA
AACGGAGCCAAAGATTTGTTATCAGACAATGTACATTTTGGTCCTGCTGGCATTGGACTCCTCATCATGGGATTCTTGGTCTTAGGATTG
GTCCCATTTTTGATGATCTGTTGTGATTGTGGAGGTGCTCCTCGTAGTGCAGCTGGCTTTGAGCCTGTTCCCGAATGTTCAGATGGAGCA
ATTCATTCATGGGCAGTAGAAGGACCACAGCCTGAACCCAGGGATATAACCACTGTCATACCACAAATACCACCTGATAACGCAAATATA
ATTGAATGCATTGACAACTCAGGAGTTTATACAAATGAGTATGGTGGCAGAGAAATGCAAGATCTGGGAGGAGGAGAGAGAATGACAGGA
TTTGAACTAACAGAGGGAGTTAAAACTTCAGGAATGCCTGAGATATGTCAAGAATACTCTGGAACATTAAGAAGAAATTCTATGAGGGAA
TGTAGAGAAGGAGGTCTGAATATGAATTTCATGGAAAGCTACTTCTGTCAGAAAGCATATGCTTACGCAGATGAAGATGAAGGACGCCCA
TCTAATGACTGTTTGCTCATATATGACATCGAAGGTGTAGGTTCCCCTGCTGGCTCTGTGGGTTGTTGTAGCTTCATTGGAGAAGACCTG
GATGACAGCTTCTTGGATACCCTGGGACCTAAATTTAAGAAGTTGGCAGACATCAGCCTAGGAAAAGAATCATATCCAGACCTTGATCCT
TCTTGGCCACCACAAAGCACTGAACCAGTTTGCCTTCCTCAGGAAACAGAGCCCGTTGTTAGTGGACACCCACCAATCTCCCCACATTTC
GGCACTACCACAGTAATTTCTGAGAGCACCTATCCCTCGGGACCTGGTGTACTGCATCCTAAGCCTATTCTCGATCCTCTGGGCTATGGT
AATGTCACTGTGACCGAGTCTTACACCACCTCTGACACTCTGAAGCCCTCTGTGCACGTTCACGATAACCGACCAGCATCAAACGTGGTA
GTGACAGAGAGAGTGGTCGGCCCAATCTCTGGCGCTGATTTGCATGGAATGTTAGAGATGCCTGACTTGCGAGATGGGTCGAATGTTATA
GTGACAGAAAGGGTAATAGCACCAAGCTCTAGTCTACCCACCTCTCTGACTATCCATCATCCTAGAGAGTCTTCAAATGTGGTAGTGACA
GAAAGAGTAATCCAACCAACTTCCGGCATGATAGGTAGTCTGAGTATGCACCCCGAGTTAGCCAATGCCCACAATGTCATTGTGACAGAG
AGGGTTGTTTCTGGTGCTGGCGTAACTGGAATTAGTGGCACCACTGGGATCAGCGGTGGCATAGGCAGCAGTGGCCTGGTTGGCACCAGC
ATGGGTGCTGGGAGCGGTGCCCTGAGTGGAGCTGGCATAAGTGGTGGTGGCATTGGCCTGAGCAGCTTGGGAGGGACAGCCAGCATTGGC
CACATGAGGAGTTCCTCTGACCATCACTTTAACCAAACCATTGGGTCCGCCTCCCCTAGCACAGCTCGAAGTCGAATCACAAAGTATAGT
ACCGTGCAATATAGCAAGTAGTCAGGACCCCAGCTCACTTTTTCATAGTCATTGTGGTTTAGATCCAATTCCCACCACTAAAAAACCAAC
AATGTGATTTATAACGCACAACTTCGTGCTCAGGTCATCTAGGAGCAAGGTGAGAAATCACAATGAGAAAAATAAATGGAAACACCACTG
CTAGGGGAGAGCTCTCCTTAGCATTCATAAACTTTTCTCTTATATTAGGACTAAGGAACTAAAACTTGAGGCAGAGTCTTCTTTGTGCCT
GAGTGGCCTGTAGTCCATCTCCAGCATGTAACTGGCCTTACGATGGCAATTGGCATCATTCTCCTTGCTCTGTTTTGCTTTTCCATATAG
CTCGAGCAAAATTCAAAAAGAACTAAATATGCAATATATGTTCATATCTATGGGAAAAATCTAAAATGTGTGCCAGATGCCCTGTTGGTT
TCACAGATAACATAAATAAAAATTCAACCACAGATTTATACAAGGGTTAACCATTTTTTTTAAGTTTGACTACATAGTCAAGTCCACAAG
CCATCAAGCACTCCTACCTTAATTATTGCACTAGAGAAAATAAATTCCAAATTAGGAAGTGTTTCCTAGGAGGAAAATTCCATTAGAGAG
TGGCAATAGGATGAGGTTTCTTCAGGGTAAACTAGCAATGCCTGAGCCTGAACCTTAATGTGGGGCCTCAGTTAAATCTCCTGTGGAGTC
AAGGATTCTTCTGATTCTAGTGTGTGTTTAGTGATAGATGTAGTCTTGACGAATATTGCTTACTGGTGAGGTTGAGGAATATCACACTCG
TCTTTCCCTTTACCACTGTGGTTTTGACTTAAGAAAGCAAAACTCACTAAGTTTACTTCTCGAATTGAAGCAAGTGAGGCCTGACATGGT
TGTCATCACTAGTGGCAAATGACCTTCCAAGTAAGCAGATGGGAACTGAATTGTGTTTTCAGGTTTTGTTTTTAGTAGGTGATATTCATT
CGTATCCAGCTCTTTATTACATAGCTCTGAAGTTAAAATGATTTACATAGGCCGAGCTGTGGACAAAAAAAAAAGAAGCAGCAGCTTGTA
GTATGCTTAAGCTTTGGGGAATTTTTTTTTAAGGGGATCTAAAAAAATGTTTTTAGAACATGTAAAATGTTTAATGGTGAAAGTTGGAAA
AGAATTCTTCTGTAAAGTAATACCATGCTAATTATTCGCTTTTAGTAAGTAAAGTAGTGGTTGCTTTAGCAAACCTCTGCTGCCATTTTG
CAGGAATCAACCAGGAACCTTTAGCAGAATTGACAATATGGTGTTGATAAGCATGAAATAATAATAGAAACCTATTCTGCTAGTTTATCT
CACCCTCTAATTTTTCTCACTAGCATAAATTTTAAATTCCTGATTTGATTTGTCAATAAGATCTTGGCTTATATATGCTGATTTATAGGT
AGTGTCCAAATTATATAGTATAACATATTTTTCTAGTTTCAAAATTTAGTAATGTCCTATTTATGATATATCATTTCTGTGTGTTTGCTA
TGTAGTATTACCCAATTAAAAATCTCTAAAAAGAATTAAAGCATTCTAAGAAAAAGGTAAATTTACTATTGCATGGTACAGAAATTTTTT

>22431_22431_3_DGKA-DSG1_DGKA_chr12_56334217_ENST00000394147_DSG1_chr18_28908151_ENST00000257192_length(amino acids)=1313AA_BP=334
MERAYPLKRSKQRKYYYEAAFLAILEKNRQMAKERGLISPSDFAQLQKYMEYSTKKVSDVLKLFEDGEMAKYVQGDAIGYEGFQQFLKIY
LEVDNVPRHLSLALFQSFETGHCLNETNVTKDVVCLNDVSCYFSLLEGGRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLD
WDVSELRPILQEMMKEIDYDGSGSVSQAEWVRAGATTVPLLVLLGLEMTLKDDGQHMWRPKRFPRPVYCNLCESSIGLGKQGLSCNLCKY
TVHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIRIYHSLTGLHCVWCHLEIHSDCAANQQVTYRISGVGIDQPP
YGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLVMILNATDADE
PNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRDGGADGMSAECECNIKILDVNDNIPYMEQSSYTI
EIQENTLNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHSIMSQYK
LKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYNML
GGKYQGTILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTSTDSSQVYSSEPGNGAKDLLSDNVHF
GPAGIGLLIMGFLVLGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSWAVEGPQPEPRDITTVIPQIPPDNANIIECIDNSGVYTNE
YGGREMQDLGGGERMTGFELTEGVKTSGMPEICQEYSGTLRRNSMRECREGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGV
GSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLGKESYPDLDPSWPPQSTEPVCLPQETEPVVSGHPPISPHFGTTTVISESTYPS
GPGVLHPKPILDPLGYGNVTVTESYTTSDTLKPSVHVHDNRPASNVVVTERVVGPISGADLHGMLEMPDLRDGSNVIVTERVIAPSSSLP
TSLTIHHPRESSNVVVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVSGAGVTGISGTTGISGGIGSSGLVGTSMGAGSGALSGAGI

--------------------------------------------------------------
>22431_22431_4_DGKA-DSG1_DGKA_chr12_56334217_ENST00000394147_DSG1_chr18_28908152_ENST00000257192_length(transcript)=5844nt_BP=1227nt
GCGGCCGCGTCTGCCTGGCCCGTCCCCTCCAGCCCAGCTCGGGCTCCAGCTCCAGCGCCGGCGCTTCAGCTGCGACCGCGAGCCCTCTCA
AGCAAGGTAGAGACCCCGCGAGCCCCCCAGCGCCCCACCCTCCCCCATCGGAAAAGGACAGGGGTAGGGAAGCCGAGGACCCACGGGCTG
CGTTCGTGCTGCTGGGTCGGGAAGGAGGAAGCGTGACAGCTGGAGCGGGCCTACCCTCTGAAGAGGTCCAAGCAACGGAAGTACTACTAC
GAAGCTGCCTTTCTGGCCATCCTTGAGAAAAATAGACAGATGGCCAAGGAGAGGGGCCTAATAAGCCCCAGTGATTTTGCCCAGCTGCAA
AAATACATGGAATACTCCACCAAAAAGGTCAGTGATGTCCTAAAGCTCTTCGAGGATGGCGAGATGGCTAAATATGTCCAAGGAGATGCC
ATTGGGTACGAGGGATTCCAGCAATTCCTGAAAATCTATCTCGAAGTGGATAATGTTCCCAGACACCTAAGCCTGGCACTGTTTCAATCC
TTTGAGACTGGTCACTGCTTAAATGAGACAAATGTGACAAAAGATGTGGTGTGTCTCAATGATGTTTCCTGCTACTTTTCCCTTCTGGAG
GGTGGTCGGCCAGAAGACAAGTTAGAATTCACCTTCAAGCTGTACGACACGGACAGAAATGGGATCCTGGACAGCTCAGAAGTGGACAAA
ATTATCCTACAGATGATGCGAGTGGCTGAATACCTGGATTGGGATGTGTCTGAGCTGAGGCCGATTCTTCAGGAGATGATGAAAGAGATT
GACTATGATGGCAGTGGCTCTGTCTCTCAAGCTGAGTGGGTCCGGGCTGGGGCCACCACCGTGCCACTGCTAGTGCTGCTGGGTCTGGAG
ATGACTCTGAAGGACGACGGACAGCACATGTGGAGGCCCAAGAGGTTCCCCAGACCAGTCTACTGCAATCTGTGCGAGTCAAGCATTGGT
CTTGGCAAACAGGGACTGAGCTGTAACCTCTGTAAGTACACTGTTCACGACCAGTGTGCCATGAAAGCCCTGCCTTGTGAAGTCAGCACC
TATGCCAAGTCTCGGAAGGACATTGGTGTCCAATCACATGTGTGGGTGCGAGGAGGCTGTGAGTCCGGGCGCTGCGACCGCTGTCAGAAA
AAGATCCGGATCTACCACAGTCTGACCGGGCTGCATTGTGTATGGTGCCACCTAGAGATTCACTCAGATTGTGCTGCAAACCAGCAAGTT
ACATACCGCATCTCTGGAGTAGGAATTGATCAGCCACCATATGGGATCTTTGTCATTAATCAGAAAACTGGTGAAATTAATATAACATCC
ATAGTTGATCGAGAGGTCACTCCTTTCTTCATTATCTACTGCCGAGCTCTGAACTCAATGGGCCAAGATTTAGAGAGGCCTCTAGAGCTC
AGAGTCAGGGTTTTGGATATAAATGACAACCCTCCAGTGTTTTCAATGGCTACATTTGCAGGACAAATAGAAGAAAATTCTAATGCAAAT
ACACTGGTGATGATACTCAATGCTACTGACGCAGATGAACCGAACAATTTGAACTCAAAAATAGCCTTCAAGATTATAAGACAAGAACCT
TCAGATTCACCAATGTTTATTATCAACAGAAATACTGGAGAAATTCGAACGATGAATAATTTTCTAGACAGAGAGCAATACGGCCAGTAT
GCTCTTGCTGTAAGAGGCTCTGACCGAGATGGCGGGGCAGATGGCATGTCAGCGGAATGTGAGTGCAACATTAAAATCCTCGATGTCAAT
GATAATATCCCTTACATGGAACAGTCTTCATATACCATAGAAATTCAAGAAAATACTCTAAATTCAAATTTGCTCGAGATTAGAGTAATT
GATTTGGATGAAGAGTTCTCAGCTAACTGGATGGCAGTAATTTTCTTTATCTCTGGAAATGAAGGAAATTGGTTTGAGATAGAAATGAAT
GAAAGAACAAATGTGGGAATTTTAAAGGTTGTTAAGCCCTTAGATTATGAAGCTATGCAGAGTCTGCAACTCAGTATTGGTGTCAGAAAT
AAAGCTGAATTTCATCATTCAATTATGTCTCAATATAAACTGAAAGCATCTGCAATTTCTGTGACTGTGTTAAATGTAATTGAAGGCCCA
GTGTTTCGTCCAGGTTCAAAGACATATGTTGTAACTGGTAATATGGGATCAAATGATAAAGTGGGAGACTTTGTAGCTACTGACCTGGAC
ACAGGTAGACCTTCAACGACTGTTAGGTATGTAATGGGAAATAATCCAGCTGACCTGCTAGCTGTTGATTCAAGAACAGGCAAACTCACT
TTGAAAAATAAAGTTACCAAGGAACAGTACAATATGCTCGGAGGAAAATACCAAGGAACGATTCTCTCTATAGATGATAATCTTCAAAGA
ACTTGCACTGGTACAATTAATATTAACATTCAAAGTTTTGGTAATGACGACAGGACTAATACAGAGCCGAACACTAAAATTACTACCAAT
ACTGGCAGACAAGAAAGTACTTCTTCCACTAACTATGATACCAGCACAACTTCTACTGACTCTAGCCAAGTATATTCTTCTGAACCCGGA
AACGGAGCCAAAGATTTGTTATCAGACAATGTACATTTTGGTCCTGCTGGCATTGGACTCCTCATCATGGGATTCTTGGTCTTAGGATTG
GTCCCATTTTTGATGATCTGTTGTGATTGTGGAGGTGCTCCTCGTAGTGCAGCTGGCTTTGAGCCTGTTCCCGAATGTTCAGATGGAGCA
ATTCATTCATGGGCAGTAGAAGGACCACAGCCTGAACCCAGGGATATAACCACTGTCATACCACAAATACCACCTGATAACGCAAATATA
ATTGAATGCATTGACAACTCAGGAGTTTATACAAATGAGTATGGTGGCAGAGAAATGCAAGATCTGGGAGGAGGAGAGAGAATGACAGGA
TTTGAACTAACAGAGGGAGTTAAAACTTCAGGAATGCCTGAGATATGTCAAGAATACTCTGGAACATTAAGAAGAAATTCTATGAGGGAA
TGTAGAGAAGGAGGTCTGAATATGAATTTCATGGAAAGCTACTTCTGTCAGAAAGCATATGCTTACGCAGATGAAGATGAAGGACGCCCA
TCTAATGACTGTTTGCTCATATATGACATCGAAGGTGTAGGTTCCCCTGCTGGCTCTGTGGGTTGTTGTAGCTTCATTGGAGAAGACCTG
GATGACAGCTTCTTGGATACCCTGGGACCTAAATTTAAGAAGTTGGCAGACATCAGCCTAGGAAAAGAATCATATCCAGACCTTGATCCT
TCTTGGCCACCACAAAGCACTGAACCAGTTTGCCTTCCTCAGGAAACAGAGCCCGTTGTTAGTGGACACCCACCAATCTCCCCACATTTC
GGCACTACCACAGTAATTTCTGAGAGCACCTATCCCTCGGGACCTGGTGTACTGCATCCTAAGCCTATTCTCGATCCTCTGGGCTATGGT
AATGTCACTGTGACCGAGTCTTACACCACCTCTGACACTCTGAAGCCCTCTGTGCACGTTCACGATAACCGACCAGCATCAAACGTGGTA
GTGACAGAGAGAGTGGTCGGCCCAATCTCTGGCGCTGATTTGCATGGAATGTTAGAGATGCCTGACTTGCGAGATGGGTCGAATGTTATA
GTGACAGAAAGGGTAATAGCACCAAGCTCTAGTCTACCCACCTCTCTGACTATCCATCATCCTAGAGAGTCTTCAAATGTGGTAGTGACA
GAAAGAGTAATCCAACCAACTTCCGGCATGATAGGTAGTCTGAGTATGCACCCCGAGTTAGCCAATGCCCACAATGTCATTGTGACAGAG
AGGGTTGTTTCTGGTGCTGGCGTAACTGGAATTAGTGGCACCACTGGGATCAGCGGTGGCATAGGCAGCAGTGGCCTGGTTGGCACCAGC
ATGGGTGCTGGGAGCGGTGCCCTGAGTGGAGCTGGCATAAGTGGTGGTGGCATTGGCCTGAGCAGCTTGGGAGGGACAGCCAGCATTGGC
CACATGAGGAGTTCCTCTGACCATCACTTTAACCAAACCATTGGGTCCGCCTCCCCTAGCACAGCTCGAAGTCGAATCACAAAGTATAGT
ACCGTGCAATATAGCAAGTAGTCAGGACCCCAGCTCACTTTTTCATAGTCATTGTGGTTTAGATCCAATTCCCACCACTAAAAAACCAAC
AATGTGATTTATAACGCACAACTTCGTGCTCAGGTCATCTAGGAGCAAGGTGAGAAATCACAATGAGAAAAATAAATGGAAACACCACTG
CTAGGGGAGAGCTCTCCTTAGCATTCATAAACTTTTCTCTTATATTAGGACTAAGGAACTAAAACTTGAGGCAGAGTCTTCTTTGTGCCT
GAGTGGCCTGTAGTCCATCTCCAGCATGTAACTGGCCTTACGATGGCAATTGGCATCATTCTCCTTGCTCTGTTTTGCTTTTCCATATAG
CTCGAGCAAAATTCAAAAAGAACTAAATATGCAATATATGTTCATATCTATGGGAAAAATCTAAAATGTGTGCCAGATGCCCTGTTGGTT
TCACAGATAACATAAATAAAAATTCAACCACAGATTTATACAAGGGTTAACCATTTTTTTTAAGTTTGACTACATAGTCAAGTCCACAAG
CCATCAAGCACTCCTACCTTAATTATTGCACTAGAGAAAATAAATTCCAAATTAGGAAGTGTTTCCTAGGAGGAAAATTCCATTAGAGAG
TGGCAATAGGATGAGGTTTCTTCAGGGTAAACTAGCAATGCCTGAGCCTGAACCTTAATGTGGGGCCTCAGTTAAATCTCCTGTGGAGTC
AAGGATTCTTCTGATTCTAGTGTGTGTTTAGTGATAGATGTAGTCTTGACGAATATTGCTTACTGGTGAGGTTGAGGAATATCACACTCG
TCTTTCCCTTTACCACTGTGGTTTTGACTTAAGAAAGCAAAACTCACTAAGTTTACTTCTCGAATTGAAGCAAGTGAGGCCTGACATGGT
TGTCATCACTAGTGGCAAATGACCTTCCAAGTAAGCAGATGGGAACTGAATTGTGTTTTCAGGTTTTGTTTTTAGTAGGTGATATTCATT
CGTATCCAGCTCTTTATTACATAGCTCTGAAGTTAAAATGATTTACATAGGCCGAGCTGTGGACAAAAAAAAAAGAAGCAGCAGCTTGTA
GTATGCTTAAGCTTTGGGGAATTTTTTTTTAAGGGGATCTAAAAAAATGTTTTTAGAACATGTAAAATGTTTAATGGTGAAAGTTGGAAA
AGAATTCTTCTGTAAAGTAATACCATGCTAATTATTCGCTTTTAGTAAGTAAAGTAGTGGTTGCTTTAGCAAACCTCTGCTGCCATTTTG
CAGGAATCAACCAGGAACCTTTAGCAGAATTGACAATATGGTGTTGATAAGCATGAAATAATAATAGAAACCTATTCTGCTAGTTTATCT
CACCCTCTAATTTTTCTCACTAGCATAAATTTTAAATTCCTGATTTGATTTGTCAATAAGATCTTGGCTTATATATGCTGATTTATAGGT
AGTGTCCAAATTATATAGTATAACATATTTTTCTAGTTTCAAAATTTAGTAATGTCCTATTTATGATATATCATTTCTGTGTGTTTGCTA
TGTAGTATTACCCAATTAAAAATCTCTAAAAAGAATTAAAGCATTCTAAGAAAAAGGTAAATTTACTATTGCATGGTACAGAAATTTTTT

>22431_22431_4_DGKA-DSG1_DGKA_chr12_56334217_ENST00000394147_DSG1_chr18_28908152_ENST00000257192_length(amino acids)=1313AA_BP=334
MERAYPLKRSKQRKYYYEAAFLAILEKNRQMAKERGLISPSDFAQLQKYMEYSTKKVSDVLKLFEDGEMAKYVQGDAIGYEGFQQFLKIY
LEVDNVPRHLSLALFQSFETGHCLNETNVTKDVVCLNDVSCYFSLLEGGRPEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLD
WDVSELRPILQEMMKEIDYDGSGSVSQAEWVRAGATTVPLLVLLGLEMTLKDDGQHMWRPKRFPRPVYCNLCESSIGLGKQGLSCNLCKY
TVHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIRIYHSLTGLHCVWCHLEIHSDCAANQQVTYRISGVGIDQPP
YGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLVMILNATDADE
PNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRDGGADGMSAECECNIKILDVNDNIPYMEQSSYTI
EIQENTLNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEFHHSIMSQYK
LKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRPSTTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYNML
GGKYQGTILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTSTDSSQVYSSEPGNGAKDLLSDNVHF
GPAGIGLLIMGFLVLGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSWAVEGPQPEPRDITTVIPQIPPDNANIIECIDNSGVYTNE
YGGREMQDLGGGERMTGFELTEGVKTSGMPEICQEYSGTLRRNSMRECREGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGV
GSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLGKESYPDLDPSWPPQSTEPVCLPQETEPVVSGHPPISPHFGTTTVISESTYPS
GPGVLHPKPILDPLGYGNVTVTESYTTSDTLKPSVHVHDNRPASNVVVTERVVGPISGADLHGMLEMPDLRDGSNVIVTERVIAPSSSLP
TSLTIHHPRESSNVVVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVSGAGVTGISGTTGISGGIGSSGLVGTSMGAGSGALSGAGI

--------------------------------------------------------------
>22431_22431_5_DGKA-DSG1_DGKA_chr12_56334217_ENST00000551156_DSG1_chr18_28908151_ENST00000257192_length(transcript)=5739nt_BP=1122nt
AGCCCAGCTCGGGCTCCAGCTCCAGCGCCGGCGCTTCAGCTGCGACCGCGAGCCCTCTCAAGCAAGGTAGAGACCCCGCGAGCCCCCCAG
CGCCCCACCCTCCCCCATCGGAAAAGGACAGGGGCCTACCCTCTGAAGAGGTCCAAGCAACGGAAGTACTACTACGAAGCTGCCTTTCTG
GCCATCCTTGAGAAAAATAGACAGATGGCCAAGGAGAGGGGCCTAATAAGCCCCAGTGATTTTGCCCAGCTGCAAAAATACATGGAATAC
TCCACCAAAAAGGTCAGTGATGTCCTAAAGCTCTTCGAGGATGGCGAGATGGCTAAATATGTCCAAGGAGATGCCATTGGGTACGAGGGA
TTCCAGCAATTCCTGAAAATCTATCTCGAAGTGGATAATGTTCCCAGACACCTAAGCCTGGCACTGTTTCAATCCTTTGAGACTGGTCAC
TGCTTAAATGAGACAAATGTGACAAAAGATGTGGTGTGTCTCAATGATGTTTCCTGCTACTTTTCCCTTCTGGAGGGTGGTCGGCCAGAA
GACAAGTTAGAATTCACCTTCAAGCTGTACGACACGGACAGAAATGGGATCCTGGACAGCTCAGAAGTGGACAAAATTATCCTACAGATG
ATGCGAGTGGCTGAATACCTGGATTGGGATGTGTCTGAGCTGAGGCCGATTCTTCAGGAGATGATGAAAGAGATTGACTATGATGGCAGT
GGCTCTGTCTCTCAAGCTGAGTGGGTCCGGGCTGGGGCCACCACCGTGCCACTGCTAGTGCTGCTGGGTCTGGAGATGACTCTGAAGGAC
GACGGACAGCACATGTGGAGGCCCAAGAGGTTCCCCAGACCAGTCTACTGCAATCTGTGCGAGTCAAGCATTGGTCTTGGCAAACAGGGA
CTGAGCTGTAACCTCTGTAAGTACACTGTTCACGACCAGTGTGCCATGAAAGCCCTGCCTTGTGAAGTCAGCACCTATGCCAAGTCTCGG
AAGGACATTGGTGTCCAATCACATGTGTGGGTGCGAGGAGGCTGTGAGTCCGGGCGCTGCGACCGCTGTCAGAAAAAGATCCGGATCTAC
CACAGTCTGACCGGGCTGCATTGTGTATGGTGCCACCTAGAGATTCACTCAGATTGTGCTGCAAACCAGCAAGTTACATACCGCATCTCT
GGAGTAGGAATTGATCAGCCACCATATGGGATCTTTGTCATTAATCAGAAAACTGGTGAAATTAATATAACATCCATAGTTGATCGAGAG
GTCACTCCTTTCTTCATTATCTACTGCCGAGCTCTGAACTCAATGGGCCAAGATTTAGAGAGGCCTCTAGAGCTCAGAGTCAGGGTTTTG
GATATAAATGACAACCCTCCAGTGTTTTCAATGGCTACATTTGCAGGACAAATAGAAGAAAATTCTAATGCAAATACACTGGTGATGATA
CTCAATGCTACTGACGCAGATGAACCGAACAATTTGAACTCAAAAATAGCCTTCAAGATTATAAGACAAGAACCTTCAGATTCACCAATG
TTTATTATCAACAGAAATACTGGAGAAATTCGAACGATGAATAATTTTCTAGACAGAGAGCAATACGGCCAGTATGCTCTTGCTGTAAGA
GGCTCTGACCGAGATGGCGGGGCAGATGGCATGTCAGCGGAATGTGAGTGCAACATTAAAATCCTCGATGTCAATGATAATATCCCTTAC
ATGGAACAGTCTTCATATACCATAGAAATTCAAGAAAATACTCTAAATTCAAATTTGCTCGAGATTAGAGTAATTGATTTGGATGAAGAG
TTCTCAGCTAACTGGATGGCAGTAATTTTCTTTATCTCTGGAAATGAAGGAAATTGGTTTGAGATAGAAATGAATGAAAGAACAAATGTG
GGAATTTTAAAGGTTGTTAAGCCCTTAGATTATGAAGCTATGCAGAGTCTGCAACTCAGTATTGGTGTCAGAAATAAAGCTGAATTTCAT
CATTCAATTATGTCTCAATATAAACTGAAAGCATCTGCAATTTCTGTGACTGTGTTAAATGTAATTGAAGGCCCAGTGTTTCGTCCAGGT
TCAAAGACATATGTTGTAACTGGTAATATGGGATCAAATGATAAAGTGGGAGACTTTGTAGCTACTGACCTGGACACAGGTAGACCTTCA
ACGACTGTTAGGTATGTAATGGGAAATAATCCAGCTGACCTGCTAGCTGTTGATTCAAGAACAGGCAAACTCACTTTGAAAAATAAAGTT
ACCAAGGAACAGTACAATATGCTCGGAGGAAAATACCAAGGAACGATTCTCTCTATAGATGATAATCTTCAAAGAACTTGCACTGGTACA
ATTAATATTAACATTCAAAGTTTTGGTAATGACGACAGGACTAATACAGAGCCGAACACTAAAATTACTACCAATACTGGCAGACAAGAA
AGTACTTCTTCCACTAACTATGATACCAGCACAACTTCTACTGACTCTAGCCAAGTATATTCTTCTGAACCCGGAAACGGAGCCAAAGAT
TTGTTATCAGACAATGTACATTTTGGTCCTGCTGGCATTGGACTCCTCATCATGGGATTCTTGGTCTTAGGATTGGTCCCATTTTTGATG
ATCTGTTGTGATTGTGGAGGTGCTCCTCGTAGTGCAGCTGGCTTTGAGCCTGTTCCCGAATGTTCAGATGGAGCAATTCATTCATGGGCA
GTAGAAGGACCACAGCCTGAACCCAGGGATATAACCACTGTCATACCACAAATACCACCTGATAACGCAAATATAATTGAATGCATTGAC
AACTCAGGAGTTTATACAAATGAGTATGGTGGCAGAGAAATGCAAGATCTGGGAGGAGGAGAGAGAATGACAGGATTTGAACTAACAGAG
GGAGTTAAAACTTCAGGAATGCCTGAGATATGTCAAGAATACTCTGGAACATTAAGAAGAAATTCTATGAGGGAATGTAGAGAAGGAGGT
CTGAATATGAATTTCATGGAAAGCTACTTCTGTCAGAAAGCATATGCTTACGCAGATGAAGATGAAGGACGCCCATCTAATGACTGTTTG
CTCATATATGACATCGAAGGTGTAGGTTCCCCTGCTGGCTCTGTGGGTTGTTGTAGCTTCATTGGAGAAGACCTGGATGACAGCTTCTTG
GATACCCTGGGACCTAAATTTAAGAAGTTGGCAGACATCAGCCTAGGAAAAGAATCATATCCAGACCTTGATCCTTCTTGGCCACCACAA
AGCACTGAACCAGTTTGCCTTCCTCAGGAAACAGAGCCCGTTGTTAGTGGACACCCACCAATCTCCCCACATTTCGGCACTACCACAGTA
ATTTCTGAGAGCACCTATCCCTCGGGACCTGGTGTACTGCATCCTAAGCCTATTCTCGATCCTCTGGGCTATGGTAATGTCACTGTGACC
GAGTCTTACACCACCTCTGACACTCTGAAGCCCTCTGTGCACGTTCACGATAACCGACCAGCATCAAACGTGGTAGTGACAGAGAGAGTG
GTCGGCCCAATCTCTGGCGCTGATTTGCATGGAATGTTAGAGATGCCTGACTTGCGAGATGGGTCGAATGTTATAGTGACAGAAAGGGTA
ATAGCACCAAGCTCTAGTCTACCCACCTCTCTGACTATCCATCATCCTAGAGAGTCTTCAAATGTGGTAGTGACAGAAAGAGTAATCCAA
CCAACTTCCGGCATGATAGGTAGTCTGAGTATGCACCCCGAGTTAGCCAATGCCCACAATGTCATTGTGACAGAGAGGGTTGTTTCTGGT
GCTGGCGTAACTGGAATTAGTGGCACCACTGGGATCAGCGGTGGCATAGGCAGCAGTGGCCTGGTTGGCACCAGCATGGGTGCTGGGAGC
GGTGCCCTGAGTGGAGCTGGCATAAGTGGTGGTGGCATTGGCCTGAGCAGCTTGGGAGGGACAGCCAGCATTGGCCACATGAGGAGTTCC
TCTGACCATCACTTTAACCAAACCATTGGGTCCGCCTCCCCTAGCACAGCTCGAAGTCGAATCACAAAGTATAGTACCGTGCAATATAGC
AAGTAGTCAGGACCCCAGCTCACTTTTTCATAGTCATTGTGGTTTAGATCCAATTCCCACCACTAAAAAACCAACAATGTGATTTATAAC
GCACAACTTCGTGCTCAGGTCATCTAGGAGCAAGGTGAGAAATCACAATGAGAAAAATAAATGGAAACACCACTGCTAGGGGAGAGCTCT
CCTTAGCATTCATAAACTTTTCTCTTATATTAGGACTAAGGAACTAAAACTTGAGGCAGAGTCTTCTTTGTGCCTGAGTGGCCTGTAGTC
CATCTCCAGCATGTAACTGGCCTTACGATGGCAATTGGCATCATTCTCCTTGCTCTGTTTTGCTTTTCCATATAGCTCGAGCAAAATTCA
AAAAGAACTAAATATGCAATATATGTTCATATCTATGGGAAAAATCTAAAATGTGTGCCAGATGCCCTGTTGGTTTCACAGATAACATAA
ATAAAAATTCAACCACAGATTTATACAAGGGTTAACCATTTTTTTTAAGTTTGACTACATAGTCAAGTCCACAAGCCATCAAGCACTCCT
ACCTTAATTATTGCACTAGAGAAAATAAATTCCAAATTAGGAAGTGTTTCCTAGGAGGAAAATTCCATTAGAGAGTGGCAATAGGATGAG
GTTTCTTCAGGGTAAACTAGCAATGCCTGAGCCTGAACCTTAATGTGGGGCCTCAGTTAAATCTCCTGTGGAGTCAAGGATTCTTCTGAT
TCTAGTGTGTGTTTAGTGATAGATGTAGTCTTGACGAATATTGCTTACTGGTGAGGTTGAGGAATATCACACTCGTCTTTCCCTTTACCA
CTGTGGTTTTGACTTAAGAAAGCAAAACTCACTAAGTTTACTTCTCGAATTGAAGCAAGTGAGGCCTGACATGGTTGTCATCACTAGTGG
CAAATGACCTTCCAAGTAAGCAGATGGGAACTGAATTGTGTTTTCAGGTTTTGTTTTTAGTAGGTGATATTCATTCGTATCCAGCTCTTT
ATTACATAGCTCTGAAGTTAAAATGATTTACATAGGCCGAGCTGTGGACAAAAAAAAAAGAAGCAGCAGCTTGTAGTATGCTTAAGCTTT
GGGGAATTTTTTTTTAAGGGGATCTAAAAAAATGTTTTTAGAACATGTAAAATGTTTAATGGTGAAAGTTGGAAAAGAATTCTTCTGTAA
AGTAATACCATGCTAATTATTCGCTTTTAGTAAGTAAAGTAGTGGTTGCTTTAGCAAACCTCTGCTGCCATTTTGCAGGAATCAACCAGG
AACCTTTAGCAGAATTGACAATATGGTGTTGATAAGCATGAAATAATAATAGAAACCTATTCTGCTAGTTTATCTCACCCTCTAATTTTT
CTCACTAGCATAAATTTTAAATTCCTGATTTGATTTGTCAATAAGATCTTGGCTTATATATGCTGATTTATAGGTAGTGTCCAAATTATA
TAGTATAACATATTTTTCTAGTTTCAAAATTTAGTAATGTCCTATTTATGATATATCATTTCTGTGTGTTTGCTATGTAGTATTACCCAA
TTAAAAATCTCTAAAAAGAATTAAAGCATTCTAAGAAAAAGGTAAATTTACTATTGCATGGTACAGAAATTTTTTCTTTCTTAAATACAA

>22431_22431_5_DGKA-DSG1_DGKA_chr12_56334217_ENST00000551156_DSG1_chr18_28908151_ENST00000257192_length(amino acids)=1338AA_BP=359
MRPRALSSKVETPRAPQRPTLPHRKRTGAYPLKRSKQRKYYYEAAFLAILEKNRQMAKERGLISPSDFAQLQKYMEYSTKKVSDVLKLFE
DGEMAKYVQGDAIGYEGFQQFLKIYLEVDNVPRHLSLALFQSFETGHCLNETNVTKDVVCLNDVSCYFSLLEGGRPEDKLEFTFKLYDTD
RNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDGSGSVSQAEWVRAGATTVPLLVLLGLEMTLKDDGQHMWRPKRFPR
PVYCNLCESSIGLGKQGLSCNLCKYTVHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIRIYHSLTGLHCVWCHL
EIHSDCAANQQVTYRISGVGIDQPPYGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMAT
FAGQIEENSNANTLVMILNATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRDGGADGMSA
ECECNIKILDVNDNIPYMEQSSYTIEIQENTLNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEA
MQSLQLSIGVRNKAEFHHSIMSQYKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRPSTTVRYVMGNNPAD
LLAVDSRTGKLTLKNKVTKEQYNMLGGKYQGTILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTS
TDSSQVYSSEPGNGAKDLLSDNVHFGPAGIGLLIMGFLVLGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSWAVEGPQPEPRDITT
VIPQIPPDNANIIECIDNSGVYTNEYGGREMQDLGGGERMTGFELTEGVKTSGMPEICQEYSGTLRRNSMRECREGGLNMNFMESYFCQK
AYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLGKESYPDLDPSWPPQSTEPVCLPQETEP
VVSGHPPISPHFGTTTVISESTYPSGPGVLHPKPILDPLGYGNVTVTESYTTSDTLKPSVHVHDNRPASNVVVTERVVGPISGADLHGML
EMPDLRDGSNVIVTERVIAPSSSLPTSLTIHHPRESSNVVVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVSGAGVTGISGTTGIS

--------------------------------------------------------------
>22431_22431_6_DGKA-DSG1_DGKA_chr12_56334217_ENST00000551156_DSG1_chr18_28908152_ENST00000257192_length(transcript)=5739nt_BP=1122nt
AGCCCAGCTCGGGCTCCAGCTCCAGCGCCGGCGCTTCAGCTGCGACCGCGAGCCCTCTCAAGCAAGGTAGAGACCCCGCGAGCCCCCCAG
CGCCCCACCCTCCCCCATCGGAAAAGGACAGGGGCCTACCCTCTGAAGAGGTCCAAGCAACGGAAGTACTACTACGAAGCTGCCTTTCTG
GCCATCCTTGAGAAAAATAGACAGATGGCCAAGGAGAGGGGCCTAATAAGCCCCAGTGATTTTGCCCAGCTGCAAAAATACATGGAATAC
TCCACCAAAAAGGTCAGTGATGTCCTAAAGCTCTTCGAGGATGGCGAGATGGCTAAATATGTCCAAGGAGATGCCATTGGGTACGAGGGA
TTCCAGCAATTCCTGAAAATCTATCTCGAAGTGGATAATGTTCCCAGACACCTAAGCCTGGCACTGTTTCAATCCTTTGAGACTGGTCAC
TGCTTAAATGAGACAAATGTGACAAAAGATGTGGTGTGTCTCAATGATGTTTCCTGCTACTTTTCCCTTCTGGAGGGTGGTCGGCCAGAA
GACAAGTTAGAATTCACCTTCAAGCTGTACGACACGGACAGAAATGGGATCCTGGACAGCTCAGAAGTGGACAAAATTATCCTACAGATG
ATGCGAGTGGCTGAATACCTGGATTGGGATGTGTCTGAGCTGAGGCCGATTCTTCAGGAGATGATGAAAGAGATTGACTATGATGGCAGT
GGCTCTGTCTCTCAAGCTGAGTGGGTCCGGGCTGGGGCCACCACCGTGCCACTGCTAGTGCTGCTGGGTCTGGAGATGACTCTGAAGGAC
GACGGACAGCACATGTGGAGGCCCAAGAGGTTCCCCAGACCAGTCTACTGCAATCTGTGCGAGTCAAGCATTGGTCTTGGCAAACAGGGA
CTGAGCTGTAACCTCTGTAAGTACACTGTTCACGACCAGTGTGCCATGAAAGCCCTGCCTTGTGAAGTCAGCACCTATGCCAAGTCTCGG
AAGGACATTGGTGTCCAATCACATGTGTGGGTGCGAGGAGGCTGTGAGTCCGGGCGCTGCGACCGCTGTCAGAAAAAGATCCGGATCTAC
CACAGTCTGACCGGGCTGCATTGTGTATGGTGCCACCTAGAGATTCACTCAGATTGTGCTGCAAACCAGCAAGTTACATACCGCATCTCT
GGAGTAGGAATTGATCAGCCACCATATGGGATCTTTGTCATTAATCAGAAAACTGGTGAAATTAATATAACATCCATAGTTGATCGAGAG
GTCACTCCTTTCTTCATTATCTACTGCCGAGCTCTGAACTCAATGGGCCAAGATTTAGAGAGGCCTCTAGAGCTCAGAGTCAGGGTTTTG
GATATAAATGACAACCCTCCAGTGTTTTCAATGGCTACATTTGCAGGACAAATAGAAGAAAATTCTAATGCAAATACACTGGTGATGATA
CTCAATGCTACTGACGCAGATGAACCGAACAATTTGAACTCAAAAATAGCCTTCAAGATTATAAGACAAGAACCTTCAGATTCACCAATG
TTTATTATCAACAGAAATACTGGAGAAATTCGAACGATGAATAATTTTCTAGACAGAGAGCAATACGGCCAGTATGCTCTTGCTGTAAGA
GGCTCTGACCGAGATGGCGGGGCAGATGGCATGTCAGCGGAATGTGAGTGCAACATTAAAATCCTCGATGTCAATGATAATATCCCTTAC
ATGGAACAGTCTTCATATACCATAGAAATTCAAGAAAATACTCTAAATTCAAATTTGCTCGAGATTAGAGTAATTGATTTGGATGAAGAG
TTCTCAGCTAACTGGATGGCAGTAATTTTCTTTATCTCTGGAAATGAAGGAAATTGGTTTGAGATAGAAATGAATGAAAGAACAAATGTG
GGAATTTTAAAGGTTGTTAAGCCCTTAGATTATGAAGCTATGCAGAGTCTGCAACTCAGTATTGGTGTCAGAAATAAAGCTGAATTTCAT
CATTCAATTATGTCTCAATATAAACTGAAAGCATCTGCAATTTCTGTGACTGTGTTAAATGTAATTGAAGGCCCAGTGTTTCGTCCAGGT
TCAAAGACATATGTTGTAACTGGTAATATGGGATCAAATGATAAAGTGGGAGACTTTGTAGCTACTGACCTGGACACAGGTAGACCTTCA
ACGACTGTTAGGTATGTAATGGGAAATAATCCAGCTGACCTGCTAGCTGTTGATTCAAGAACAGGCAAACTCACTTTGAAAAATAAAGTT
ACCAAGGAACAGTACAATATGCTCGGAGGAAAATACCAAGGAACGATTCTCTCTATAGATGATAATCTTCAAAGAACTTGCACTGGTACA
ATTAATATTAACATTCAAAGTTTTGGTAATGACGACAGGACTAATACAGAGCCGAACACTAAAATTACTACCAATACTGGCAGACAAGAA
AGTACTTCTTCCACTAACTATGATACCAGCACAACTTCTACTGACTCTAGCCAAGTATATTCTTCTGAACCCGGAAACGGAGCCAAAGAT
TTGTTATCAGACAATGTACATTTTGGTCCTGCTGGCATTGGACTCCTCATCATGGGATTCTTGGTCTTAGGATTGGTCCCATTTTTGATG
ATCTGTTGTGATTGTGGAGGTGCTCCTCGTAGTGCAGCTGGCTTTGAGCCTGTTCCCGAATGTTCAGATGGAGCAATTCATTCATGGGCA
GTAGAAGGACCACAGCCTGAACCCAGGGATATAACCACTGTCATACCACAAATACCACCTGATAACGCAAATATAATTGAATGCATTGAC
AACTCAGGAGTTTATACAAATGAGTATGGTGGCAGAGAAATGCAAGATCTGGGAGGAGGAGAGAGAATGACAGGATTTGAACTAACAGAG
GGAGTTAAAACTTCAGGAATGCCTGAGATATGTCAAGAATACTCTGGAACATTAAGAAGAAATTCTATGAGGGAATGTAGAGAAGGAGGT
CTGAATATGAATTTCATGGAAAGCTACTTCTGTCAGAAAGCATATGCTTACGCAGATGAAGATGAAGGACGCCCATCTAATGACTGTTTG
CTCATATATGACATCGAAGGTGTAGGTTCCCCTGCTGGCTCTGTGGGTTGTTGTAGCTTCATTGGAGAAGACCTGGATGACAGCTTCTTG
GATACCCTGGGACCTAAATTTAAGAAGTTGGCAGACATCAGCCTAGGAAAAGAATCATATCCAGACCTTGATCCTTCTTGGCCACCACAA
AGCACTGAACCAGTTTGCCTTCCTCAGGAAACAGAGCCCGTTGTTAGTGGACACCCACCAATCTCCCCACATTTCGGCACTACCACAGTA
ATTTCTGAGAGCACCTATCCCTCGGGACCTGGTGTACTGCATCCTAAGCCTATTCTCGATCCTCTGGGCTATGGTAATGTCACTGTGACC
GAGTCTTACACCACCTCTGACACTCTGAAGCCCTCTGTGCACGTTCACGATAACCGACCAGCATCAAACGTGGTAGTGACAGAGAGAGTG
GTCGGCCCAATCTCTGGCGCTGATTTGCATGGAATGTTAGAGATGCCTGACTTGCGAGATGGGTCGAATGTTATAGTGACAGAAAGGGTA
ATAGCACCAAGCTCTAGTCTACCCACCTCTCTGACTATCCATCATCCTAGAGAGTCTTCAAATGTGGTAGTGACAGAAAGAGTAATCCAA
CCAACTTCCGGCATGATAGGTAGTCTGAGTATGCACCCCGAGTTAGCCAATGCCCACAATGTCATTGTGACAGAGAGGGTTGTTTCTGGT
GCTGGCGTAACTGGAATTAGTGGCACCACTGGGATCAGCGGTGGCATAGGCAGCAGTGGCCTGGTTGGCACCAGCATGGGTGCTGGGAGC
GGTGCCCTGAGTGGAGCTGGCATAAGTGGTGGTGGCATTGGCCTGAGCAGCTTGGGAGGGACAGCCAGCATTGGCCACATGAGGAGTTCC
TCTGACCATCACTTTAACCAAACCATTGGGTCCGCCTCCCCTAGCACAGCTCGAAGTCGAATCACAAAGTATAGTACCGTGCAATATAGC
AAGTAGTCAGGACCCCAGCTCACTTTTTCATAGTCATTGTGGTTTAGATCCAATTCCCACCACTAAAAAACCAACAATGTGATTTATAAC
GCACAACTTCGTGCTCAGGTCATCTAGGAGCAAGGTGAGAAATCACAATGAGAAAAATAAATGGAAACACCACTGCTAGGGGAGAGCTCT
CCTTAGCATTCATAAACTTTTCTCTTATATTAGGACTAAGGAACTAAAACTTGAGGCAGAGTCTTCTTTGTGCCTGAGTGGCCTGTAGTC
CATCTCCAGCATGTAACTGGCCTTACGATGGCAATTGGCATCATTCTCCTTGCTCTGTTTTGCTTTTCCATATAGCTCGAGCAAAATTCA
AAAAGAACTAAATATGCAATATATGTTCATATCTATGGGAAAAATCTAAAATGTGTGCCAGATGCCCTGTTGGTTTCACAGATAACATAA
ATAAAAATTCAACCACAGATTTATACAAGGGTTAACCATTTTTTTTAAGTTTGACTACATAGTCAAGTCCACAAGCCATCAAGCACTCCT
ACCTTAATTATTGCACTAGAGAAAATAAATTCCAAATTAGGAAGTGTTTCCTAGGAGGAAAATTCCATTAGAGAGTGGCAATAGGATGAG
GTTTCTTCAGGGTAAACTAGCAATGCCTGAGCCTGAACCTTAATGTGGGGCCTCAGTTAAATCTCCTGTGGAGTCAAGGATTCTTCTGAT
TCTAGTGTGTGTTTAGTGATAGATGTAGTCTTGACGAATATTGCTTACTGGTGAGGTTGAGGAATATCACACTCGTCTTTCCCTTTACCA
CTGTGGTTTTGACTTAAGAAAGCAAAACTCACTAAGTTTACTTCTCGAATTGAAGCAAGTGAGGCCTGACATGGTTGTCATCACTAGTGG
CAAATGACCTTCCAAGTAAGCAGATGGGAACTGAATTGTGTTTTCAGGTTTTGTTTTTAGTAGGTGATATTCATTCGTATCCAGCTCTTT
ATTACATAGCTCTGAAGTTAAAATGATTTACATAGGCCGAGCTGTGGACAAAAAAAAAAGAAGCAGCAGCTTGTAGTATGCTTAAGCTTT
GGGGAATTTTTTTTTAAGGGGATCTAAAAAAATGTTTTTAGAACATGTAAAATGTTTAATGGTGAAAGTTGGAAAAGAATTCTTCTGTAA
AGTAATACCATGCTAATTATTCGCTTTTAGTAAGTAAAGTAGTGGTTGCTTTAGCAAACCTCTGCTGCCATTTTGCAGGAATCAACCAGG
AACCTTTAGCAGAATTGACAATATGGTGTTGATAAGCATGAAATAATAATAGAAACCTATTCTGCTAGTTTATCTCACCCTCTAATTTTT
CTCACTAGCATAAATTTTAAATTCCTGATTTGATTTGTCAATAAGATCTTGGCTTATATATGCTGATTTATAGGTAGTGTCCAAATTATA
TAGTATAACATATTTTTCTAGTTTCAAAATTTAGTAATGTCCTATTTATGATATATCATTTCTGTGTGTTTGCTATGTAGTATTACCCAA
TTAAAAATCTCTAAAAAGAATTAAAGCATTCTAAGAAAAAGGTAAATTTACTATTGCATGGTACAGAAATTTTTTCTTTCTTAAATACAA

>22431_22431_6_DGKA-DSG1_DGKA_chr12_56334217_ENST00000551156_DSG1_chr18_28908152_ENST00000257192_length(amino acids)=1338AA_BP=359
MRPRALSSKVETPRAPQRPTLPHRKRTGAYPLKRSKQRKYYYEAAFLAILEKNRQMAKERGLISPSDFAQLQKYMEYSTKKVSDVLKLFE
DGEMAKYVQGDAIGYEGFQQFLKIYLEVDNVPRHLSLALFQSFETGHCLNETNVTKDVVCLNDVSCYFSLLEGGRPEDKLEFTFKLYDTD
RNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDGSGSVSQAEWVRAGATTVPLLVLLGLEMTLKDDGQHMWRPKRFPR
PVYCNLCESSIGLGKQGLSCNLCKYTVHDQCAMKALPCEVSTYAKSRKDIGVQSHVWVRGGCESGRCDRCQKKIRIYHSLTGLHCVWCHL
EIHSDCAANQQVTYRISGVGIDQPPYGIFVINQKTGEINITSIVDREVTPFFIIYCRALNSMGQDLERPLELRVRVLDINDNPPVFSMAT
FAGQIEENSNANTLVMILNATDADEPNNLNSKIAFKIIRQEPSDSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRDGGADGMSA
ECECNIKILDVNDNIPYMEQSSYTIEIQENTLNSNLLEIRVIDLDEEFSANWMAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEA
MQSLQLSIGVRNKAEFHHSIMSQYKLKASAISVTVLNVIEGPVFRPGSKTYVVTGNMGSNDKVGDFVATDLDTGRPSTTVRYVMGNNPAD
LLAVDSRTGKLTLKNKVTKEQYNMLGGKYQGTILSIDDNLQRTCTGTININIQSFGNDDRTNTEPNTKITTNTGRQESTSSTNYDTSTTS
TDSSQVYSSEPGNGAKDLLSDNVHFGPAGIGLLIMGFLVLGLVPFLMICCDCGGAPRSAAGFEPVPECSDGAIHSWAVEGPQPEPRDITT
VIPQIPPDNANIIECIDNSGVYTNEYGGREMQDLGGGERMTGFELTEGVKTSGMPEICQEYSGTLRRNSMRECREGGLNMNFMESYFCQK
AYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIGEDLDDSFLDTLGPKFKKLADISLGKESYPDLDPSWPPQSTEPVCLPQETEP
VVSGHPPISPHFGTTTVISESTYPSGPGVLHPKPILDPLGYGNVTVTESYTTSDTLKPSVHVHDNRPASNVVVTERVVGPISGADLHGML
EMPDLRDGSNVIVTERVIAPSSSLPTSLTIHHPRESSNVVVTERVIQPTSGMIGSLSMHPELANAHNVIVTERVVSGAGVTGISGTTGIS

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for DGKA-DSG1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for DGKA-DSG1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for DGKA-DSG1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource