FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:DIP2B-SPATS2 (FusionGDB2 ID:22851)

Fusion Gene Summary for DIP2B-SPATS2

check button Fusion gene summary
Fusion gene informationFusion gene name: DIP2B-SPATS2
Fusion gene ID: 22851
HgeneTgene
Gene symbol

DIP2B

SPATS2

Gene ID

57609

65244

Gene namedisco interacting protein 2 homolog Bspermatogenesis associated serine rich 2
Synonyms-Nbla00526|P59SCR|SCR59|SPATA10
Cytomap

12q13.12

12q13.12

Type of geneprotein-codingprotein-coding
Descriptiondisco-interacting protein 2 homolog BDIP2 disco-interacting protein 2 homolog Bspermatogenesis-associated serine-rich protein 2putative protein product of Nbla00526serine-rich spermatocytes and round spermatid 59 kDa proteinserine-rich spermatocytes and round spermatid protein
Modification date2020031320200315
UniProtAcc

Q9P265

SPATS2L

Ensembl transtripts involved in fusion geneENST00000301180, ENST00000547865, 
ENST00000552557, ENST00000321898, 
ENST00000553127, ENST00000552918, 
Fusion gene scores* DoF score19 X 15 X 11=313512 X 14 X 7=1176
# samples 2415
** MAII scorelog2(24/3135*10)=-3.70735913208088
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/1176*10)=-2.97085365434048
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DIP2B [Title/Abstract] AND SPATS2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDIP2B(51108379)-SPATS2(49919727), # samples:5
Anticipated loss of major functional domain due to fusion event.DIP2B-SPATS2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
DIP2B-SPATS2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across DIP2B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SPATS2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-BL-A0C8-01ADIP2Bchr12

51108379

-SPATS2chr12

49919727

+
ChimerDB4BLCATCGA-BL-A0C8-01ADIP2Bchr12

51108379

+SPATS2chr12

49919727

+
ChimerDB4BLCATCGA-BL-A0C8-01ADIP2Bchr12

51108379

+SPATS2chr12

49919861

+
ChimerDB4BLCATCGA-BL-A0C8-01BDIP2Bchr12

51108379

+SPATS2chr12

49919727

+
ChimerDB4BLCATCGA-BL-A0C8DIP2Bchr12

51108379

+SPATS2chr12

49919726

+


Top

Fusion Gene ORF analysis for DIP2B-SPATS2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000301180ENST00000547865DIP2Bchr12

51108379

+SPATS2chr12

49919727

+
5CDS-intronENST00000301180ENST00000547865DIP2Bchr12

51108379

+SPATS2chr12

49919861

+
5CDS-intronENST00000301180ENST00000547865DIP2Bchr12

51108379

+SPATS2chr12

49919726

+
5CDS-intronENST00000301180ENST00000552557DIP2Bchr12

51108379

+SPATS2chr12

49919727

+
5CDS-intronENST00000301180ENST00000552557DIP2Bchr12

51108379

+SPATS2chr12

49919861

+
5CDS-intronENST00000301180ENST00000552557DIP2Bchr12

51108379

+SPATS2chr12

49919726

+
Frame-shiftENST00000301180ENST00000321898DIP2Bchr12

51108379

+SPATS2chr12

49919727

+
Frame-shiftENST00000301180ENST00000321898DIP2Bchr12

51108379

+SPATS2chr12

49919861

+
Frame-shiftENST00000301180ENST00000321898DIP2Bchr12

51108379

+SPATS2chr12

49919726

+
Frame-shiftENST00000301180ENST00000553127DIP2Bchr12

51108379

+SPATS2chr12

49919727

+
Frame-shiftENST00000301180ENST00000553127DIP2Bchr12

51108379

+SPATS2chr12

49919861

+
Frame-shiftENST00000301180ENST00000553127DIP2Bchr12

51108379

+SPATS2chr12

49919726

+
In-frameENST00000301180ENST00000552918DIP2Bchr12

51108379

+SPATS2chr12

49919727

+
In-frameENST00000301180ENST00000552918DIP2Bchr12

51108379

+SPATS2chr12

49919861

+
In-frameENST00000301180ENST00000552918DIP2Bchr12

51108379

+SPATS2chr12

49919726

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000301180DIP2Bchr1251108379+ENST00000552918SPATS2chr1249919727+41682885342922962
ENST00000301180DIP2Bchr1251108379+ENST00000552918SPATS2chr1249919726+41682885342922962
ENST00000301180DIP2Bchr1251108379+ENST00000552918SPATS2chr1249919861+40332885342925963

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000301180ENST00000552918DIP2Bchr1251108379+SPATS2chr1249919727+0.0011040040.998896
ENST00000301180ENST00000552918DIP2Bchr1251108379+SPATS2chr1249919726+0.0011040040.998896
ENST00000301180ENST00000552918DIP2Bchr1251108379+SPATS2chr1249919861+0.001083440.9989166

Top

Fusion Genomic Features for DIP2B-SPATS2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DIP2Bchr1251108379+SPATS2chr1249919726+0.0003016720.9996984
DIP2Bchr1251108379+SPATS2chr1249919726+0.0003016720.9996984
DIP2Bchr1251108379+SPATS2chr1249919726+0.0003016720.9996984
DIP2Bchr1251108379+SPATS2chr1249919726+0.0003016720.9996984
DIP2Bchr1251108379+SPATS2chr1249919726+0.0003016720.9996984
DIP2Bchr1251108379+SPATS2chr1249919726+0.0003016720.9996984

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for DIP2B-SPATS2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:51108379/chr12:49919727)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DIP2B

Q9P265

SPATS2

SPATS2L

FUNCTION: Negatively regulates axonal outgrowth and is essential for normal synaptic transmission. Not required for regulation of axon polarity. Promotes acetylation of alpha-tubulin. {ECO:0000250|UniProtKB:Q3UH60}.558

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDIP2Bchr12:51108379chr12:49919726ENST00000301180+2338145_2349501577.0Compositional biasNote=Ser-rich
HgeneDIP2Bchr12:51108379chr12:49919727ENST00000301180+2338145_2349501577.0Compositional biasNote=Ser-rich
HgeneDIP2Bchr12:51108379chr12:49919861ENST00000301180+2338145_2349501577.0Compositional biasNote=Ser-rich
HgeneDIP2Bchr12:51108379chr12:49919726ENST00000301180+233812_1319501577.0DomainDMAP1-binding
HgeneDIP2Bchr12:51108379chr12:49919727ENST00000301180+233812_1319501577.0DomainDMAP1-binding
HgeneDIP2Bchr12:51108379chr12:49919861ENST00000301180+233812_1319501577.0DomainDMAP1-binding
TgeneSPATS2chr12:51108379chr12:49919861ENST00000321898013364_4140546.0Compositional biasNote=Ser-rich
TgeneSPATS2chr12:51108379chr12:49919861ENST0000032189801386_970546.0Compositional biasNote=Poly-Lys
TgeneSPATS2chr12:51108379chr12:49919861ENST00000552918014364_4140546.0Compositional biasNote=Ser-rich
TgeneSPATS2chr12:51108379chr12:49919861ENST0000055291801486_970546.0Compositional biasNote=Poly-Lys
TgeneSPATS2chr12:51108379chr12:49919861ENST00000553127015364_4140546.0Compositional biasNote=Ser-rich
TgeneSPATS2chr12:51108379chr12:49919861ENST0000055312701586_970546.0Compositional biasNote=Poly-Lys

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDIP2Bchr12:51108379chr12:49919726ENST00000301180+23381118_11219501577.0Compositional biasNote=Poly-Ala
HgeneDIP2Bchr12:51108379chr12:49919726ENST00000301180+23381503_15069501577.0Compositional biasNote=Poly-Val
HgeneDIP2Bchr12:51108379chr12:49919726ENST00000301180+23381534_15409501577.0Compositional biasNote=Poly-Val
HgeneDIP2Bchr12:51108379chr12:49919727ENST00000301180+23381118_11219501577.0Compositional biasNote=Poly-Ala
HgeneDIP2Bchr12:51108379chr12:49919727ENST00000301180+23381503_15069501577.0Compositional biasNote=Poly-Val
HgeneDIP2Bchr12:51108379chr12:49919727ENST00000301180+23381534_15409501577.0Compositional biasNote=Poly-Val
HgeneDIP2Bchr12:51108379chr12:49919861ENST00000301180+23381118_11219501577.0Compositional biasNote=Poly-Ala
HgeneDIP2Bchr12:51108379chr12:49919861ENST00000301180+23381503_15069501577.0Compositional biasNote=Poly-Val
HgeneDIP2Bchr12:51108379chr12:49919861ENST00000301180+23381534_15409501577.0Compositional biasNote=Poly-Val
TgeneSPATS2chr12:51108379chr12:49919726ENST000003218981113364_414442546.0Compositional biasNote=Ser-rich
TgeneSPATS2chr12:51108379chr12:49919726ENST00000321898111386_97442546.0Compositional biasNote=Poly-Lys
TgeneSPATS2chr12:51108379chr12:49919726ENST000005529181214364_414442546.0Compositional biasNote=Ser-rich
TgeneSPATS2chr12:51108379chr12:49919726ENST00000552918121486_97442546.0Compositional biasNote=Poly-Lys
TgeneSPATS2chr12:51108379chr12:49919726ENST000005531271315364_414442546.0Compositional biasNote=Ser-rich
TgeneSPATS2chr12:51108379chr12:49919726ENST00000553127131586_97442546.0Compositional biasNote=Poly-Lys
TgeneSPATS2chr12:51108379chr12:49919727ENST000003218981113364_414442546.0Compositional biasNote=Ser-rich
TgeneSPATS2chr12:51108379chr12:49919727ENST00000321898111386_97442546.0Compositional biasNote=Poly-Lys
TgeneSPATS2chr12:51108379chr12:49919727ENST000005529181214364_414442546.0Compositional biasNote=Ser-rich
TgeneSPATS2chr12:51108379chr12:49919727ENST00000552918121486_97442546.0Compositional biasNote=Poly-Lys
TgeneSPATS2chr12:51108379chr12:49919727ENST000005531271315364_414442546.0Compositional biasNote=Ser-rich
TgeneSPATS2chr12:51108379chr12:49919727ENST00000553127131586_97442546.0Compositional biasNote=Poly-Lys


Top

Fusion Gene Sequence for DIP2B-SPATS2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>22851_22851_1_DIP2B-SPATS2_DIP2B_chr12_51108379_ENST00000301180_SPATS2_chr12_49919726_ENST00000552918_length(transcript)=4168nt_BP=2885nt
TCTTGTCTTCCGGAGTGTGGCTGGCGGAGCTGGGATGGCGGAACGAGGCCTGGAGCCGTCGCCGGCCGCGGTGGCGGCGCTGCCGCCTGA
AGTGCGGGCGCAGCTGGCGGAGCTGGAGCTGGAGCTCTCGGAGGGGGACATCACCCAGAAGGGCTATGAAAAGAAAAGGTCCAAACTCCT
ATCTCCTTACAGCCCGCAGACACAAGAAACTGATTCAGCAGTACAGAAAGAACTTAGAAACCAGACACCTGCTCCATCTGCAGCTCAAAC
TTCTGCTCCCTCTAAGTACCACCGAACTCGATCTGGGGGAGCCAGGGATGAACGATATCGATCAGATATCCACACAGAAGCAGTTCAGGC
TGCACTGGCAAAGCATAAAGAACAGAAGATGGCTTTGCCCATGCCAACCAAAAGGCGATCCACATTTGTTCAGTCTCCTGCAGATGCCTG
CACACCTCCTGACACATCTTCGGCCTCTGAGGATGAGGGCTCTCTGAGACGCCAAGCTGCGCTCTCTGCTGCCTTGCAACAGAGCTTACA
GAATGCTGAGTCCTGGATCAACCGTTCAATTCAGGGATCGTCCACTTCTTCATCCGCATCTTCTACGCTGTCCCACGGAGAGGTCAAAGG
AACCAGTGGGTCTCTAGCTGATGTATTTGCCAATACTCGAATAGAGAATTTCTCTGCTCCTCCTGATGTCACTACAACTACCTCTTCCTC
CTCATCATCTTCCTCAATTCGCCCAGCAAACATTGACCTGCCCCCCTCGGGGATAGTTAAAGGCATGCACAAAGGATCCAACAGGTCCAG
CCTTATGGATACAGCTGATGGTGTTCCTGTCAGTAGCAGAGTATCTACAAAAATCCAGCAGCTTCTGAACACTCTGAAACGACCCAAAAG
GCCTCCCTTAAAGGAATTTTTTGTGGATGACTCTGAAGAAATTGTGGAAGTACCTCAGCCAGACCCCAACCAGCCCAAGCCGGAGGGACG
GCAGATGACCCCTGTGAAAGGAGAGCCTTTAGGAGTCATCTGTAACTGGCCTCCTGCTCTTGAATCTGCCCTGCAGCGCTGGGGTACCAC
TCAAGCAAAATGCTCCTGTCTGACTGCACTGGACATGACAGGGAAACCAGTTTACACTCTTACATATGGAAAGTTGTGGAGCAGAAGTTT
AAAGTTGGCCTACACACTTCTTAATAAACTGGGGACCAAAAATGAACCTGTGTTAAAACCTGGAGACAGGGTAGCCCTGGTTTACCCCAA
CAATGATCCAGTCATGTTTATGGTGGCTTTCTATGGATGCCTCCTGGCAGAAGTGATTCCAGTGCCTATAGAGGTACCTCTTACCAGAAA
GGATGCTGGAGGTCAGCAGATTGGCTTCTTGCTAGGAAGCTGTGGTATTGCCTTAGCTCTTACCAGTGAAGTTTGTCTAAAAGGACTGCC
AAAAACCCAGAATGGAGAAATTGTACAGTTTAAAGGTTGGCCCCGGCTCAAATGGGTTGTAACAGATTCCAAGTACCTTTCAAAGCCACC
GAAAGACTGGCAGCCACACATCTCACCTGCTGGGACAGAACCGGCATACATTGAGTATAAAACAAGCAAAGAAGGGAGTGTAATGGGAGT
TACAGTATCCCGGCTTGCAATGTTGTCTCACTGCCAAGCTCTGTCGCAGGCCTGCAATTATTCTGAAGGGGAAACAATAGTAAATGTCTT
AGACTTTAAGAAGGATGCTGGGCTGTGGCACGGCATGTTTGCGAATGTAATGAATAAGATGCACACAATCAGCGTACCCTACTCTGTTAT
GAAAACCTGTCCTCTCTCTTGGGTCCAAAGAGTACATGCTCACAAAGCCAAGGTAGCTTTAGTAAAATGTCGGGACTTGCACTGGGCTAT
GATGGCACATCGGGACCAAAGAGACGTGAGCTTGAGTTCCCTCCGAATGTTAATTGTGACTGATGGAGCTAACCCCTGGTCCGTGTCATC
CTGTGATGCCTTCCTGAGTCTGTTCCAAAGTCATGGACTGAAGCCTGAGGCCATCTGTCCGTGCGCCACGTCTGCTGAAGCCATGACTGT
AGCAATCCGCAGGCCTGGAGTTCCAGGAGCCCCTTTGCCAGGAAGAGCCATTCTCTCAATGAATGGATTGAGCTATGGGGTAATACGGGT
CAATACTGAAGATAAAAATTCAGCACTGACGGTCCAGGATGTAGGGCATGTAATGCCTGGTGGGATGATGTGCATTGTGAAACCAGATGG
ACCTCCCCAGCTCTGCAAAACAGATGAAATTGGAGAAATCTGTGTTAGCTCCAGAACTGGAGGCATGATGTACTTTGGGCTTGCTGGTGT
GACAAAAAATACATTTGAGGTAATTCCAGTGAATTCTGCAGGCTCTCCTGTTGGGGATGTGCCATTCATCCGATCAGGATTGCTGGGGTT
TGTAGGGCCGGGTAGTTTGGTGTTCGTGGTTGGGAAAATGGATGGCTTACTGATGGTTAGTGGTCGAAGACATAATGCTGATGACATTGT
TGCTACTGGATTGGCTGTAGAATCAATAAAGACTGTTTATAGAGGAAGAATTGCTGTGTTTTCTGTGTCTGTATTTTATGATGAGCGCAT
TGTGGTGGTTGCGGAACAAAGACCTGATGCTTCTGAGGAAGATAGTTTCCAGTGGATGAGCCGCGTGCTGCAGGCGATCGATAGCATTCA
TCAAGTGGGGGTTTATTGTCTTGCTCTGGTGCCAGCCAATACATTGCCAAAAACTCCACTAGGAGGAATCCATATATCTCAGACGAAACA
ACTCTTTCTGGAGGGATCACTGCATCCTTGCAACATCCTCATGTGCCCCCATACATGTGTGACAAACTTGCCAAAGCCCCGGCAAAAACA
ACCAGGTATTGCCAGGGAACAGACGAGGAGGACAGGGCTATAGGCCACAAGGCCAAAAGTCCAATGACCCCATGAACCAAGGGCGGCATG
ACAGTATGGGTCGTTACAGAAACAGCTCGTGGTATTCATCTGGTTCCAGGTATCAGAGTGCTCCATCTCAGGCACCAGGAAACACCATTG
AAAGAGGCCAGACTCACTCTGCAGGGACCAATGGAACTGGAGTCAGCATGGAGCCCAGCCCTCCCACGCCTTCATTCAAAAAGGGGCTCC
CCCAGCGCAAACCCAGGACCTCTCAGACTGAAGCCGTGAACTCTTGAGAGAAAATCCAGTTGGCCTCTCTCCTCTATCCACACAATTCAA
CTTGATAACTGGACTTTAGGAAACTTACAGTTAGATGTAATAACAAAAAGAAGTTTATGCGTATCACTTTTTGTGCCATTCTAAGTATTT
TTGGTTTCTTGTCTCCTTATTTCCTCTTTACCATTTTTGGAGGGGAAGCTATTTTTTTTCCTTGATCTTTCCCAGTGATATGGATTGAAT
CTGGTTGGTCATTTCCACCAGGAATCAGAGGCAGCTGTTACCAGGTTTCGGCCTTCCAGTTGATCCCTCCACTGTCCAGGCTGTCTCAGG
AGGAGGTGAATCAGAGCTAGTCTGTCACCTTTCCAATCTAAGCCGAAGCCACAGGTGCCTGACAGGTTCCCTTCTAACAACTATTTGACC
AAGAGAGGCAATCAGGGGGTTGTATACTGCACTGGATTCGCCAGAGAAGGGAAAATTTAATTAGTGAAAAGGAAAGAACACTAGGAAACA
TTTGAGAACCTGCCTCTATCCCAGAATGTGCTGGAGATTTGACACTCAAATCAGTGTTTAGTCTTCTGCTTGGCACCATAGCTTAACCTG
CAGTTTCTTCAAAATGCCCAATGCCTTGTTTCCTATTACCTTAGATTGCAAACCAGTCTAGGGAAGTCTATGAGAAAGTAGCATTTAATT
AAAGTTTAAAAAAAAAAAGGTTGGGCGTTGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGATCACTAGGTCAG
GAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTGTACTAAAAATACAAAAATTAGCTGAGCATGGTGGCGTGTGCCTGTAAT
CTCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCGGAGGCTGCAGTGAGCTGAGATTGTGCCACTGCACTCCAG

>22851_22851_1_DIP2B-SPATS2_DIP2B_chr12_51108379_ENST00000301180_SPATS2_chr12_49919726_ENST00000552918_length(amino acids)=962AA_BP=
MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETDSAVQKELRNQTPAPSAAQTSAPSKYHRTRS
GGARDERYRSDIHTEAVQAALAKHKEQKMALPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ
GSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTTTSSSSSSSSIRPANIDLPPSGIVKGMHKGSNRSSLMDTADGVPVS
SRVSTKIQQLLNTLKRPKRPPLKEFFVDDSEEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGTTQAKCSCLTALD
MTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVYPNNDPVMFMVAFYGCLLAEVIPVPIEVPLTRKDAGGQQIGFLL
GSCGIALALTSEVCLKGLPKTQNGEIVQFKGWPRLKWVVTDSKYLSKPPKDWQPHISPAGTEPAYIEYKTSKEGSVMGVTVSRLAMLSHC
QALSQACNYSEGETIVNVLDFKKDAGLWHGMFANVMNKMHTISVPYSVMKTCPLSWVQRVHAHKAKVALVKCRDLHWAMMAHRDQRDVSL
SSLRMLIVTDGANPWSVSSCDAFLSLFQSHGLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVIRVNTEDKNSALTV
QDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVIPVNSAGSPVGDVPFIRSGLLGFVGPGSLVFVVG
KMDGLLMVSGRRHNADDIVATGLAVESIKTVYRGRIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVP

--------------------------------------------------------------
>22851_22851_2_DIP2B-SPATS2_DIP2B_chr12_51108379_ENST00000301180_SPATS2_chr12_49919727_ENST00000552918_length(transcript)=4168nt_BP=2885nt
TCTTGTCTTCCGGAGTGTGGCTGGCGGAGCTGGGATGGCGGAACGAGGCCTGGAGCCGTCGCCGGCCGCGGTGGCGGCGCTGCCGCCTGA
AGTGCGGGCGCAGCTGGCGGAGCTGGAGCTGGAGCTCTCGGAGGGGGACATCACCCAGAAGGGCTATGAAAAGAAAAGGTCCAAACTCCT
ATCTCCTTACAGCCCGCAGACACAAGAAACTGATTCAGCAGTACAGAAAGAACTTAGAAACCAGACACCTGCTCCATCTGCAGCTCAAAC
TTCTGCTCCCTCTAAGTACCACCGAACTCGATCTGGGGGAGCCAGGGATGAACGATATCGATCAGATATCCACACAGAAGCAGTTCAGGC
TGCACTGGCAAAGCATAAAGAACAGAAGATGGCTTTGCCCATGCCAACCAAAAGGCGATCCACATTTGTTCAGTCTCCTGCAGATGCCTG
CACACCTCCTGACACATCTTCGGCCTCTGAGGATGAGGGCTCTCTGAGACGCCAAGCTGCGCTCTCTGCTGCCTTGCAACAGAGCTTACA
GAATGCTGAGTCCTGGATCAACCGTTCAATTCAGGGATCGTCCACTTCTTCATCCGCATCTTCTACGCTGTCCCACGGAGAGGTCAAAGG
AACCAGTGGGTCTCTAGCTGATGTATTTGCCAATACTCGAATAGAGAATTTCTCTGCTCCTCCTGATGTCACTACAACTACCTCTTCCTC
CTCATCATCTTCCTCAATTCGCCCAGCAAACATTGACCTGCCCCCCTCGGGGATAGTTAAAGGCATGCACAAAGGATCCAACAGGTCCAG
CCTTATGGATACAGCTGATGGTGTTCCTGTCAGTAGCAGAGTATCTACAAAAATCCAGCAGCTTCTGAACACTCTGAAACGACCCAAAAG
GCCTCCCTTAAAGGAATTTTTTGTGGATGACTCTGAAGAAATTGTGGAAGTACCTCAGCCAGACCCCAACCAGCCCAAGCCGGAGGGACG
GCAGATGACCCCTGTGAAAGGAGAGCCTTTAGGAGTCATCTGTAACTGGCCTCCTGCTCTTGAATCTGCCCTGCAGCGCTGGGGTACCAC
TCAAGCAAAATGCTCCTGTCTGACTGCACTGGACATGACAGGGAAACCAGTTTACACTCTTACATATGGAAAGTTGTGGAGCAGAAGTTT
AAAGTTGGCCTACACACTTCTTAATAAACTGGGGACCAAAAATGAACCTGTGTTAAAACCTGGAGACAGGGTAGCCCTGGTTTACCCCAA
CAATGATCCAGTCATGTTTATGGTGGCTTTCTATGGATGCCTCCTGGCAGAAGTGATTCCAGTGCCTATAGAGGTACCTCTTACCAGAAA
GGATGCTGGAGGTCAGCAGATTGGCTTCTTGCTAGGAAGCTGTGGTATTGCCTTAGCTCTTACCAGTGAAGTTTGTCTAAAAGGACTGCC
AAAAACCCAGAATGGAGAAATTGTACAGTTTAAAGGTTGGCCCCGGCTCAAATGGGTTGTAACAGATTCCAAGTACCTTTCAAAGCCACC
GAAAGACTGGCAGCCACACATCTCACCTGCTGGGACAGAACCGGCATACATTGAGTATAAAACAAGCAAAGAAGGGAGTGTAATGGGAGT
TACAGTATCCCGGCTTGCAATGTTGTCTCACTGCCAAGCTCTGTCGCAGGCCTGCAATTATTCTGAAGGGGAAACAATAGTAAATGTCTT
AGACTTTAAGAAGGATGCTGGGCTGTGGCACGGCATGTTTGCGAATGTAATGAATAAGATGCACACAATCAGCGTACCCTACTCTGTTAT
GAAAACCTGTCCTCTCTCTTGGGTCCAAAGAGTACATGCTCACAAAGCCAAGGTAGCTTTAGTAAAATGTCGGGACTTGCACTGGGCTAT
GATGGCACATCGGGACCAAAGAGACGTGAGCTTGAGTTCCCTCCGAATGTTAATTGTGACTGATGGAGCTAACCCCTGGTCCGTGTCATC
CTGTGATGCCTTCCTGAGTCTGTTCCAAAGTCATGGACTGAAGCCTGAGGCCATCTGTCCGTGCGCCACGTCTGCTGAAGCCATGACTGT
AGCAATCCGCAGGCCTGGAGTTCCAGGAGCCCCTTTGCCAGGAAGAGCCATTCTCTCAATGAATGGATTGAGCTATGGGGTAATACGGGT
CAATACTGAAGATAAAAATTCAGCACTGACGGTCCAGGATGTAGGGCATGTAATGCCTGGTGGGATGATGTGCATTGTGAAACCAGATGG
ACCTCCCCAGCTCTGCAAAACAGATGAAATTGGAGAAATCTGTGTTAGCTCCAGAACTGGAGGCATGATGTACTTTGGGCTTGCTGGTGT
GACAAAAAATACATTTGAGGTAATTCCAGTGAATTCTGCAGGCTCTCCTGTTGGGGATGTGCCATTCATCCGATCAGGATTGCTGGGGTT
TGTAGGGCCGGGTAGTTTGGTGTTCGTGGTTGGGAAAATGGATGGCTTACTGATGGTTAGTGGTCGAAGACATAATGCTGATGACATTGT
TGCTACTGGATTGGCTGTAGAATCAATAAAGACTGTTTATAGAGGAAGAATTGCTGTGTTTTCTGTGTCTGTATTTTATGATGAGCGCAT
TGTGGTGGTTGCGGAACAAAGACCTGATGCTTCTGAGGAAGATAGTTTCCAGTGGATGAGCCGCGTGCTGCAGGCGATCGATAGCATTCA
TCAAGTGGGGGTTTATTGTCTTGCTCTGGTGCCAGCCAATACATTGCCAAAAACTCCACTAGGAGGAATCCATATATCTCAGACGAAACA
ACTCTTTCTGGAGGGATCACTGCATCCTTGCAACATCCTCATGTGCCCCCATACATGTGTGACAAACTTGCCAAAGCCCCGGCAAAAACA
ACCAGGTATTGCCAGGGAACAGACGAGGAGGACAGGGCTATAGGCCACAAGGCCAAAAGTCCAATGACCCCATGAACCAAGGGCGGCATG
ACAGTATGGGTCGTTACAGAAACAGCTCGTGGTATTCATCTGGTTCCAGGTATCAGAGTGCTCCATCTCAGGCACCAGGAAACACCATTG
AAAGAGGCCAGACTCACTCTGCAGGGACCAATGGAACTGGAGTCAGCATGGAGCCCAGCCCTCCCACGCCTTCATTCAAAAAGGGGCTCC
CCCAGCGCAAACCCAGGACCTCTCAGACTGAAGCCGTGAACTCTTGAGAGAAAATCCAGTTGGCCTCTCTCCTCTATCCACACAATTCAA
CTTGATAACTGGACTTTAGGAAACTTACAGTTAGATGTAATAACAAAAAGAAGTTTATGCGTATCACTTTTTGTGCCATTCTAAGTATTT
TTGGTTTCTTGTCTCCTTATTTCCTCTTTACCATTTTTGGAGGGGAAGCTATTTTTTTTCCTTGATCTTTCCCAGTGATATGGATTGAAT
CTGGTTGGTCATTTCCACCAGGAATCAGAGGCAGCTGTTACCAGGTTTCGGCCTTCCAGTTGATCCCTCCACTGTCCAGGCTGTCTCAGG
AGGAGGTGAATCAGAGCTAGTCTGTCACCTTTCCAATCTAAGCCGAAGCCACAGGTGCCTGACAGGTTCCCTTCTAACAACTATTTGACC
AAGAGAGGCAATCAGGGGGTTGTATACTGCACTGGATTCGCCAGAGAAGGGAAAATTTAATTAGTGAAAAGGAAAGAACACTAGGAAACA
TTTGAGAACCTGCCTCTATCCCAGAATGTGCTGGAGATTTGACACTCAAATCAGTGTTTAGTCTTCTGCTTGGCACCATAGCTTAACCTG
CAGTTTCTTCAAAATGCCCAATGCCTTGTTTCCTATTACCTTAGATTGCAAACCAGTCTAGGGAAGTCTATGAGAAAGTAGCATTTAATT
AAAGTTTAAAAAAAAAAAGGTTGGGCGTTGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGATCACTAGGTCAG
GAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTGTACTAAAAATACAAAAATTAGCTGAGCATGGTGGCGTGTGCCTGTAAT
CTCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAGGAGGCGGAGGCTGCAGTGAGCTGAGATTGTGCCACTGCACTCCAG

>22851_22851_2_DIP2B-SPATS2_DIP2B_chr12_51108379_ENST00000301180_SPATS2_chr12_49919727_ENST00000552918_length(amino acids)=962AA_BP=
MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETDSAVQKELRNQTPAPSAAQTSAPSKYHRTRS
GGARDERYRSDIHTEAVQAALAKHKEQKMALPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ
GSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTTTSSSSSSSSIRPANIDLPPSGIVKGMHKGSNRSSLMDTADGVPVS
SRVSTKIQQLLNTLKRPKRPPLKEFFVDDSEEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGTTQAKCSCLTALD
MTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVYPNNDPVMFMVAFYGCLLAEVIPVPIEVPLTRKDAGGQQIGFLL
GSCGIALALTSEVCLKGLPKTQNGEIVQFKGWPRLKWVVTDSKYLSKPPKDWQPHISPAGTEPAYIEYKTSKEGSVMGVTVSRLAMLSHC
QALSQACNYSEGETIVNVLDFKKDAGLWHGMFANVMNKMHTISVPYSVMKTCPLSWVQRVHAHKAKVALVKCRDLHWAMMAHRDQRDVSL
SSLRMLIVTDGANPWSVSSCDAFLSLFQSHGLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVIRVNTEDKNSALTV
QDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVIPVNSAGSPVGDVPFIRSGLLGFVGPGSLVFVVG
KMDGLLMVSGRRHNADDIVATGLAVESIKTVYRGRIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVP

--------------------------------------------------------------
>22851_22851_3_DIP2B-SPATS2_DIP2B_chr12_51108379_ENST00000301180_SPATS2_chr12_49919861_ENST00000552918_length(transcript)=4033nt_BP=2885nt
TCTTGTCTTCCGGAGTGTGGCTGGCGGAGCTGGGATGGCGGAACGAGGCCTGGAGCCGTCGCCGGCCGCGGTGGCGGCGCTGCCGCCTGA
AGTGCGGGCGCAGCTGGCGGAGCTGGAGCTGGAGCTCTCGGAGGGGGACATCACCCAGAAGGGCTATGAAAAGAAAAGGTCCAAACTCCT
ATCTCCTTACAGCCCGCAGACACAAGAAACTGATTCAGCAGTACAGAAAGAACTTAGAAACCAGACACCTGCTCCATCTGCAGCTCAAAC
TTCTGCTCCCTCTAAGTACCACCGAACTCGATCTGGGGGAGCCAGGGATGAACGATATCGATCAGATATCCACACAGAAGCAGTTCAGGC
TGCACTGGCAAAGCATAAAGAACAGAAGATGGCTTTGCCCATGCCAACCAAAAGGCGATCCACATTTGTTCAGTCTCCTGCAGATGCCTG
CACACCTCCTGACACATCTTCGGCCTCTGAGGATGAGGGCTCTCTGAGACGCCAAGCTGCGCTCTCTGCTGCCTTGCAACAGAGCTTACA
GAATGCTGAGTCCTGGATCAACCGTTCAATTCAGGGATCGTCCACTTCTTCATCCGCATCTTCTACGCTGTCCCACGGAGAGGTCAAAGG
AACCAGTGGGTCTCTAGCTGATGTATTTGCCAATACTCGAATAGAGAATTTCTCTGCTCCTCCTGATGTCACTACAACTACCTCTTCCTC
CTCATCATCTTCCTCAATTCGCCCAGCAAACATTGACCTGCCCCCCTCGGGGATAGTTAAAGGCATGCACAAAGGATCCAACAGGTCCAG
CCTTATGGATACAGCTGATGGTGTTCCTGTCAGTAGCAGAGTATCTACAAAAATCCAGCAGCTTCTGAACACTCTGAAACGACCCAAAAG
GCCTCCCTTAAAGGAATTTTTTGTGGATGACTCTGAAGAAATTGTGGAAGTACCTCAGCCAGACCCCAACCAGCCCAAGCCGGAGGGACG
GCAGATGACCCCTGTGAAAGGAGAGCCTTTAGGAGTCATCTGTAACTGGCCTCCTGCTCTTGAATCTGCCCTGCAGCGCTGGGGTACCAC
TCAAGCAAAATGCTCCTGTCTGACTGCACTGGACATGACAGGGAAACCAGTTTACACTCTTACATATGGAAAGTTGTGGAGCAGAAGTTT
AAAGTTGGCCTACACACTTCTTAATAAACTGGGGACCAAAAATGAACCTGTGTTAAAACCTGGAGACAGGGTAGCCCTGGTTTACCCCAA
CAATGATCCAGTCATGTTTATGGTGGCTTTCTATGGATGCCTCCTGGCAGAAGTGATTCCAGTGCCTATAGAGGTACCTCTTACCAGAAA
GGATGCTGGAGGTCAGCAGATTGGCTTCTTGCTAGGAAGCTGTGGTATTGCCTTAGCTCTTACCAGTGAAGTTTGTCTAAAAGGACTGCC
AAAAACCCAGAATGGAGAAATTGTACAGTTTAAAGGTTGGCCCCGGCTCAAATGGGTTGTAACAGATTCCAAGTACCTTTCAAAGCCACC
GAAAGACTGGCAGCCACACATCTCACCTGCTGGGACAGAACCGGCATACATTGAGTATAAAACAAGCAAAGAAGGGAGTGTAATGGGAGT
TACAGTATCCCGGCTTGCAATGTTGTCTCACTGCCAAGCTCTGTCGCAGGCCTGCAATTATTCTGAAGGGGAAACAATAGTAAATGTCTT
AGACTTTAAGAAGGATGCTGGGCTGTGGCACGGCATGTTTGCGAATGTAATGAATAAGATGCACACAATCAGCGTACCCTACTCTGTTAT
GAAAACCTGTCCTCTCTCTTGGGTCCAAAGAGTACATGCTCACAAAGCCAAGGTAGCTTTAGTAAAATGTCGGGACTTGCACTGGGCTAT
GATGGCACATCGGGACCAAAGAGACGTGAGCTTGAGTTCCCTCCGAATGTTAATTGTGACTGATGGAGCTAACCCCTGGTCCGTGTCATC
CTGTGATGCCTTCCTGAGTCTGTTCCAAAGTCATGGACTGAAGCCTGAGGCCATCTGTCCGTGCGCCACGTCTGCTGAAGCCATGACTGT
AGCAATCCGCAGGCCTGGAGTTCCAGGAGCCCCTTTGCCAGGAAGAGCCATTCTCTCAATGAATGGATTGAGCTATGGGGTAATACGGGT
CAATACTGAAGATAAAAATTCAGCACTGACGGTCCAGGATGTAGGGCATGTAATGCCTGGTGGGATGATGTGCATTGTGAAACCAGATGG
ACCTCCCCAGCTCTGCAAAACAGATGAAATTGGAGAAATCTGTGTTAGCTCCAGAACTGGAGGCATGATGTACTTTGGGCTTGCTGGTGT
GACAAAAAATACATTTGAGGTAATTCCAGTGAATTCTGCAGGCTCTCCTGTTGGGGATGTGCCATTCATCCGATCAGGATTGCTGGGGTT
TGTAGGGCCGGGTAGTTTGGTGTTCGTGGTTGGGAAAATGGATGGCTTACTGATGGTTAGTGGTCGAAGACATAATGCTGATGACATTGT
TGCTACTGGATTGGCTGTAGAATCAATAAAGACTGTTTATAGAGGAAGAATTGCTGTGTTTTCTGTGTCTGTATTTTATGATGAGCGCAT
TGTGGTGGTTGCGGAACAAAGACCTGATGCTTCTGAGGAAGATAGTTTCCAGTGGATGAGCCGCGTGCTGCAGGCGATCGATAGCATTCA
TCAAGTGGGGGTTTATTGTCTTGCTCTGGTGCCAGCCAATACATTGCCAAAAACTCCACTAGGAGGAATCCATATATCTCAGACGAAACA
ACTCTTTCTGGAGGGATCACTGCATCCTTGCAACATCCTCATGTGCCCCCATACATGTGTGACAAACTTGCCAAAGCCCCGGCAAAAACA
ACCAGTATCAGAGTGCTCCATCTCAGGCACCAGGAAACACCATTGAAAGAGGCCAGACTCACTCTGCAGGGACCAATGGAACTGGAGTCA
GCATGGAGCCCAGCCCTCCCACGCCTTCATTCAAAAAGGGGCTCCCCCAGCGCAAACCCAGGACCTCTCAGACTGAAGCCGTGAACTCTT
GAGAGAAAATCCAGTTGGCCTCTCTCCTCTATCCACACAATTCAACTTGATAACTGGACTTTAGGAAACTTACAGTTAGATGTAATAACA
AAAAGAAGTTTATGCGTATCACTTTTTGTGCCATTCTAAGTATTTTTGGTTTCTTGTCTCCTTATTTCCTCTTTACCATTTTTGGAGGGG
AAGCTATTTTTTTTCCTTGATCTTTCCCAGTGATATGGATTGAATCTGGTTGGTCATTTCCACCAGGAATCAGAGGCAGCTGTTACCAGG
TTTCGGCCTTCCAGTTGATCCCTCCACTGTCCAGGCTGTCTCAGGAGGAGGTGAATCAGAGCTAGTCTGTCACCTTTCCAATCTAAGCCG
AAGCCACAGGTGCCTGACAGGTTCCCTTCTAACAACTATTTGACCAAGAGAGGCAATCAGGGGGTTGTATACTGCACTGGATTCGCCAGA
GAAGGGAAAATTTAATTAGTGAAAAGGAAAGAACACTAGGAAACATTTGAGAACCTGCCTCTATCCCAGAATGTGCTGGAGATTTGACAC
TCAAATCAGTGTTTAGTCTTCTGCTTGGCACCATAGCTTAACCTGCAGTTTCTTCAAAATGCCCAATGCCTTGTTTCCTATTACCTTAGA
TTGCAAACCAGTCTAGGGAAGTCTATGAGAAAGTAGCATTTAATTAAAGTTTAAAAAAAAAAAGGTTGGGCGTTGTGGCTCATGCCTGTA
ATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGATCACTAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTGTAC
TAAAAATACAAAAATTAGCTGAGCATGGTGGCGTGTGCCTGTAATCTCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACCCAG

>22851_22851_3_DIP2B-SPATS2_DIP2B_chr12_51108379_ENST00000301180_SPATS2_chr12_49919861_ENST00000552918_length(amino acids)=963AA_BP=
MAERGLEPSPAAVAALPPEVRAQLAELELELSEGDITQKGYEKKRSKLLSPYSPQTQETDSAVQKELRNQTPAPSAAQTSAPSKYHRTRS
GGARDERYRSDIHTEAVQAALAKHKEQKMALPMPTKRRSTFVQSPADACTPPDTSSASEDEGSLRRQAALSAALQQSLQNAESWINRSIQ
GSSTSSSASSTLSHGEVKGTSGSLADVFANTRIENFSAPPDVTTTTSSSSSSSSIRPANIDLPPSGIVKGMHKGSNRSSLMDTADGVPVS
SRVSTKIQQLLNTLKRPKRPPLKEFFVDDSEEIVEVPQPDPNQPKPEGRQMTPVKGEPLGVICNWPPALESALQRWGTTQAKCSCLTALD
MTGKPVYTLTYGKLWSRSLKLAYTLLNKLGTKNEPVLKPGDRVALVYPNNDPVMFMVAFYGCLLAEVIPVPIEVPLTRKDAGGQQIGFLL
GSCGIALALTSEVCLKGLPKTQNGEIVQFKGWPRLKWVVTDSKYLSKPPKDWQPHISPAGTEPAYIEYKTSKEGSVMGVTVSRLAMLSHC
QALSQACNYSEGETIVNVLDFKKDAGLWHGMFANVMNKMHTISVPYSVMKTCPLSWVQRVHAHKAKVALVKCRDLHWAMMAHRDQRDVSL
SSLRMLIVTDGANPWSVSSCDAFLSLFQSHGLKPEAICPCATSAEAMTVAIRRPGVPGAPLPGRAILSMNGLSYGVIRVNTEDKNSALTV
QDVGHVMPGGMMCIVKPDGPPQLCKTDEIGEICVSSRTGGMMYFGLAGVTKNTFEVIPVNSAGSPVGDVPFIRSGLLGFVGPGSLVFVVG
KMDGLLMVSGRRHNADDIVATGLAVESIKTVYRGRIAVFSVSVFYDERIVVVAEQRPDASEEDSFQWMSRVLQAIDSIHQVGVYCLALVP

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for DIP2B-SPATS2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for DIP2B-SPATS2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for DIP2B-SPATS2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource