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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DIS3-KLF12 (FusionGDB2 ID:22898)

Fusion Gene Summary for DIS3-KLF12

check button Fusion gene summary
Fusion gene informationFusion gene name: DIS3-KLF12
Fusion gene ID: 22898
HgeneTgene
Gene symbol

DIS3

KLF12

Gene ID

22894

11278

Gene nameDIS3 homolog, exosome endoribonuclease and 3'-5' exoribonucleaseKruppel like factor 12
Synonyms2810028N01Rik|EXOSC11|KIAA1008|RRP44|dis3pAP-2rep|AP2REP|HSPC122
Cytomap

13q21.33

13q22.1

Type of geneprotein-codingprotein-coding
Descriptionexosome complex exonuclease RRP44DIS3 exosome endoribonuclease and 3'-5' exoribonucleaseDIS3 mitotic control homologexosome component 11mitotic control protein dis3 homologribosomal RNA-processing protein 44Krueppel-like factor 12AP-2 repressorAP-2rep transcription factorKLF12 zinc finger transcriptional repressortranscriptional repressor AP-2rep
Modification date2020031320200313
UniProtAcc

Q9Y2L1

Q9Y4X4

Ensembl transtripts involved in fusion geneENST00000377767, ENST00000377780, 
ENST00000545453, ENST00000475871, 
ENST00000472022, ENST00000377666, 
ENST00000377669, 
Fusion gene scores* DoF score2 X 3 X 2=1213 X 13 X 6=1014
# samples 316
** MAII scorelog2(3/12*10)=1.32192809488736
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(16/1014*10)=-2.66391384211598
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DIS3 [Title/Abstract] AND KLF12 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDIS3(73345933)-KLF12(74420510), # samples:2
Anticipated loss of major functional domain due to fusion event.DIS3-KLF12 seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
DIS3-KLF12 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
DIS3-KLF12 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
DIS3-KLF12 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneKLF12

GO:0000122

negative regulation of transcription by RNA polymerase II

16615998


check buttonFusion gene breakpoints across DIS3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across KLF12 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-VQ-A922-01ADIS3chr13

73345933

-KLF12chr13

74420510

-
ChimerDB4STADTCGA-VQ-A922DIS3chr13

73345932

-KLF12chr13

74420510

-


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Fusion Gene ORF analysis for DIS3-KLF12

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000377767ENST00000472022DIS3chr13

73345933

-KLF12chr13

74420510

-
5CDS-5UTRENST00000377767ENST00000472022DIS3chr13

73345932

-KLF12chr13

74420510

-
5CDS-5UTRENST00000377780ENST00000472022DIS3chr13

73345933

-KLF12chr13

74420510

-
5CDS-5UTRENST00000377780ENST00000472022DIS3chr13

73345932

-KLF12chr13

74420510

-
5CDS-5UTRENST00000545453ENST00000472022DIS3chr13

73345933

-KLF12chr13

74420510

-
5CDS-5UTRENST00000545453ENST00000472022DIS3chr13

73345932

-KLF12chr13

74420510

-
Frame-shiftENST00000545453ENST00000377666DIS3chr13

73345933

-KLF12chr13

74420510

-
Frame-shiftENST00000545453ENST00000377666DIS3chr13

73345932

-KLF12chr13

74420510

-
Frame-shiftENST00000545453ENST00000377669DIS3chr13

73345933

-KLF12chr13

74420510

-
Frame-shiftENST00000545453ENST00000377669DIS3chr13

73345932

-KLF12chr13

74420510

-
In-frameENST00000377767ENST00000377666DIS3chr13

73345933

-KLF12chr13

74420510

-
In-frameENST00000377767ENST00000377666DIS3chr13

73345932

-KLF12chr13

74420510

-
In-frameENST00000377767ENST00000377669DIS3chr13

73345933

-KLF12chr13

74420510

-
In-frameENST00000377767ENST00000377669DIS3chr13

73345932

-KLF12chr13

74420510

-
In-frameENST00000377780ENST00000377666DIS3chr13

73345933

-KLF12chr13

74420510

-
In-frameENST00000377780ENST00000377666DIS3chr13

73345932

-KLF12chr13

74420510

-
In-frameENST00000377780ENST00000377669DIS3chr13

73345933

-KLF12chr13

74420510

-
In-frameENST00000377780ENST00000377669DIS3chr13

73345932

-KLF12chr13

74420510

-
intron-3CDSENST00000475871ENST00000377666DIS3chr13

73345933

-KLF12chr13

74420510

-
intron-3CDSENST00000475871ENST00000377666DIS3chr13

73345932

-KLF12chr13

74420510

-
intron-3CDSENST00000475871ENST00000377669DIS3chr13

73345933

-KLF12chr13

74420510

-
intron-3CDSENST00000475871ENST00000377669DIS3chr13

73345932

-KLF12chr13

74420510

-
intron-5UTRENST00000475871ENST00000472022DIS3chr13

73345933

-KLF12chr13

74420510

-
intron-5UTRENST00000475871ENST00000472022DIS3chr13

73345932

-KLF12chr13

74420510

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000377767DIS3chr1373345933-ENST00000377669KLF12chr1374420510-1219317061012791896
ENST00000377767DIS3chr1373345933-ENST00000377666KLF12chr1374420510-288317061012791896
ENST00000377780DIS3chr1373345933-ENST00000377669KLF12chr1374420510-120951608932693866
ENST00000377780DIS3chr1373345933-ENST00000377666KLF12chr1374420510-27851608932693866
ENST00000377767DIS3chr1373345932-ENST00000377669KLF12chr1374420510-1219317061012791896
ENST00000377767DIS3chr1373345932-ENST00000377666KLF12chr1374420510-288317061012791896
ENST00000377780DIS3chr1373345932-ENST00000377669KLF12chr1374420510-120951608932693866
ENST00000377780DIS3chr1373345932-ENST00000377666KLF12chr1374420510-27851608932693866

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000377767ENST00000377669DIS3chr1373345933-KLF12chr1374420510-0.0004687040.99953127
ENST00000377767ENST00000377666DIS3chr1373345933-KLF12chr1374420510-0.0013681540.9986318
ENST00000377780ENST00000377669DIS3chr1373345933-KLF12chr1374420510-0.0004503510.99954957
ENST00000377780ENST00000377666DIS3chr1373345933-KLF12chr1374420510-0.0014334430.99856657
ENST00000377767ENST00000377669DIS3chr1373345932-KLF12chr1374420510-0.0004687040.99953127
ENST00000377767ENST00000377666DIS3chr1373345932-KLF12chr1374420510-0.0013681540.9986318
ENST00000377780ENST00000377669DIS3chr1373345932-KLF12chr1374420510-0.0004503510.99954957
ENST00000377780ENST00000377666DIS3chr1373345932-KLF12chr1374420510-0.0014334430.99856657

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Fusion Genomic Features for DIS3-KLF12


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for DIS3-KLF12


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:73345933/chr13:74420510)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DIS3

Q9Y2L1

KLF12

Q9Y4X4

FUNCTION: Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. DIS3 has both 3'-5' exonuclease and endonuclease activities. {ECO:0000269|PubMed:19056938, ECO:0000269|PubMed:20531386}.FUNCTION: Confers strong transcriptional repression to the AP-2-alpha gene. Binds to a regulatory element (A32) in the AP-2-alpha gene promoter.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDIS3chr13:73345932chr13:74420510ENST00000377767-112164_182535959.0DomainNote=PINc
HgeneDIS3chr13:73345932chr13:74420510ENST00000377780-112164_182505929.0DomainNote=PINc
HgeneDIS3chr13:73345933chr13:74420510ENST00000377767-112164_182535959.0DomainNote=PINc
HgeneDIS3chr13:73345933chr13:74420510ENST00000377780-112164_182505929.0DomainNote=PINc
TgeneKLF12chr13:73345932chr13:74420510ENST000003776662880_8841403.0Motif9aaTAD%3B inactive
TgeneKLF12chr13:73345932chr13:74420510ENST000003776691780_8841403.0Motif9aaTAD%3B inactive
TgeneKLF12chr13:73345933chr13:74420510ENST000003776662880_8841403.0Motif9aaTAD%3B inactive
TgeneKLF12chr13:73345933chr13:74420510ENST000003776691780_8841403.0Motif9aaTAD%3B inactive
TgeneKLF12chr13:73345932chr13:74420510ENST0000037766628317_34141403.0Zinc fingerC2H2-type 1
TgeneKLF12chr13:73345932chr13:74420510ENST0000037766628347_37141403.0Zinc fingerC2H2-type 2
TgeneKLF12chr13:73345932chr13:74420510ENST0000037766628377_39941403.0Zinc fingerC2H2-type 3
TgeneKLF12chr13:73345932chr13:74420510ENST0000037766917317_34141403.0Zinc fingerC2H2-type 1
TgeneKLF12chr13:73345932chr13:74420510ENST0000037766917347_37141403.0Zinc fingerC2H2-type 2
TgeneKLF12chr13:73345932chr13:74420510ENST0000037766917377_39941403.0Zinc fingerC2H2-type 3
TgeneKLF12chr13:73345933chr13:74420510ENST0000037766628317_34141403.0Zinc fingerC2H2-type 1
TgeneKLF12chr13:73345933chr13:74420510ENST0000037766628347_37141403.0Zinc fingerC2H2-type 2
TgeneKLF12chr13:73345933chr13:74420510ENST0000037766628377_39941403.0Zinc fingerC2H2-type 3
TgeneKLF12chr13:73345933chr13:74420510ENST0000037766917317_34141403.0Zinc fingerC2H2-type 1
TgeneKLF12chr13:73345933chr13:74420510ENST0000037766917347_37141403.0Zinc fingerC2H2-type 2
TgeneKLF12chr13:73345933chr13:74420510ENST0000037766917377_39941403.0Zinc fingerC2H2-type 3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for DIS3-KLF12


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>22898_22898_1_DIS3-KLF12_DIS3_chr13_73345932_ENST00000377767_KLF12_chr13_74420510_ENST00000377666_length(transcript)=2883nt_BP=1706nt
GGAATGGAAAGGGAAGAACCTCCGGGGTTAGGCGTATTCTAGATTGACGCCTTTTGCTGGAAGAGCGCTGCTGGGGTTAGGATTCTGCGC
GGCGAGGCAAGATGCTCAAGTCCAAGACGTTCTTAAAAAAGACCCGGGCGGGCGGCGTGATGAAGATCGTGCGCGAGCACTACCTGCGAG
ACGACATCGGCTGCGGTGCGCCCGGGTGCGCAGCGTGTGGAGGGGCGCACGAGGGGCCGGCCCTGGAGCCGCAGCCCCAGGACCCGGCGA
GCAGCGTCTGCCCGCAACCGCACTACTTGCTGCCCGACACTAATGTGTTACTGCACCAGATTGATGTTCTTGAGGACCCTGCCATCAGGA
ATGTAATTGTGCTACAAACAGTTCTTCAAGAAGTGAGAAATCGCAGTGCCCCCGTATATAAACGCATCCGAGATGTGACTAATAACCAAG
AGAAGCATTTCTATACTTTCACTAATGAGCACCATAGAGAAACCTATGTAGAACAAGAACAGGGAGAAAATGCTAATGACAGGAATGATA
GAGCGATTCGAGTAGCAGCAAAATGGTACAATGAACATTTGAAAAAAATGTCAGCAGACAACCAGCTGCAAGTTATCTTCATAACAAATG
ACAGGAGAAACAAAGAGAAAGCCATAGAAGAAGGAATACCAGCTTTCACTTGTGAAGAATATGTAAAGAGCCTAACTGCTAACCCCGAAC
TCATAGATCGTCTTGCTTGTTTGTCTGAAGAAGGGAATGAAATAGAAAGTGGAAAAATAATATTTTCAGAGCATCTTCCCTTAAGTAAGC
TACAGCAAGGCATAAAATCTGGTACATACCTTCAAGGAACATTTAGAGCTAGCAGGGAAAATTACTTGGAAGCTACAGTATGGATTCATG
GCGACAATGAAGAAAATAAAGAGATAATCTTACAGGGACTTAAACATTTAAACAGAGCTGTTCACGAAGATATTGTGGCTGTGGAGCTTC
TCCCCAAGAGTCAGTGGGTAGCACCATCTTCTGTGGTTTTACATGATGAAGGTCAAAATGAAGAAGATGTGGAGAAAGAAGAAGAGACAG
AACGAATGCTTAAGACTGCTGTAAGCGAGAAAATGTTGAAGCCTACAGGTAGAGTTGTAGGAATAATAAAAAGGAATTGGAGACCATATT
GTGGCATGCTTTCCAAGTCTGACATTAAGGAGTCAAGAAGACATCTCTTTACACCTGCTGATAAGAGAATCCCTCGAATTCGCATAGAAA
CCAGACAGGCTTCCACATTAGAAGGACGGAGAATTATTGTTGCTATTGATGGTTGGCCCAGAAATTCCAGATATCCAAATGGACACTTTG
TGAGAAATTTAGGTGATGTTGGAGAGAAAGAGACTGAAACAGAAGTTTTGTTACTTGAACACGATGTTCCCCATCAGCCTTTTTCACAGG
CTGTTCTTAGTTTTCTGCCAAAGATGCCCTGGAGCATTACTGAAAAGGACATGAAAAACCGAGAAGACCTGAGGCATCTGTGTATTTGTA
GTGTAGACCCACCAGGATGTACTGATATAGACGATGCTCTACATTGTCGAGAACTCGAAAATGGAAATTTGGAGGTTGGTGTTCATATTG
CTGATGTGAGCCATTTTATTAGGCCAGGAAATGCCTTGGATCAAGAATCAGCCAGAAGAGGAACAACTGTGTATCTTTGTGAAAAGTCTC
CAAACGTCCACAACTATCCCGATATGGAAGCCGTTCCCCTGTTGCTAAATAATGTGAAAGGGGAGCCCCCGGAGGACTCGTTATCTGTAG
ATCACTTCCAAACACAAACTGAGCCAGTGGACTTGTCAATAAACAAAGCCAGGACGTCCCCTACTGCCGTTTCATCCTCCCCAGTTTCCA
TGACAGCATCTGCCTCCTCACCTTCTTCAACTTCAACCTCTTCATCGTCTTCTAGTCGTCTAGCCTCATCCCCAACTGTTATCACATCAG
TATCTTCAGCGTCATCTTCGTCAACAGTATTAACTCCAGGGCCCCTTGTGGCCTCTGCATCTGGTGTTGGAGGCCAGCAGTTTTTGCACA
TTATCCATCCCGTACCGCCTTCAAGTCCCATGAATTTACAGTCTAACAAACTGAGTCATGTTCACCGCATCCCCGTGGTGGTACAGTCGG
TGCCTGTTGTCTACACAGCTGTAAGGTCACCTGGAAATGTGAACAACACTATTGTCGTGCCGCTTTTGGAGGATGGGAGAGGCCATGGCA
AAGCACAAATGGACCCCCGAGGCCTATCTCCCAGACAAAGTAAAAGTGACAGTGATGATGATGACCTGCCAAATGTGACCTTAGATAGCG
TTAATGAAACTGGATCTACGGCCCTTTCCATAGCCAGAGCAGTACAAGAGGTACATCCGTCCCCAGTATCAAGGGTCCGGGGCAATCGAA
TGAATAATCAAAAGTTTCCTTGTTCAATTTCACCATTTAGTATTGAGAGCACAAGACGCCAGAGACGGTCTGAATCCCCAGACTCCAGAA
AACGGCGTATCCACAGATGTGATTTTGAGGGATGCAACAAAGTGTACACAAAAAGTTCTCACCTGAAGGCTCACCGGAGGACACATACAG
GAGAGAAACCTTACAAGTGTACCTGGGAAGGCTGCACCTGGAAGTTCGCTCGTTCAGATGAACTGACGAGGCATTACCGCAAACATACGG
GAGTGAAGCCATTCAAGTGCGCGGACTGTGATCGCAGCTTTTCCCGGTCAGATCATTTGGCCCTGCACCGCCGGAGGCATATGTTGGTGT
GAGGAATGCTACCTGTCCAGCTGAGCGTAAGAGCTGGATCTCTTAGCGGCACCCAATTCAGCAGGGCTGAATCCCCTTCACAGTGTTAAC

>22898_22898_1_DIS3-KLF12_DIS3_chr13_73345932_ENST00000377767_KLF12_chr13_74420510_ENST00000377666_length(amino acids)=896AA_BP=535
MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVCPQPHYLLPDTNVLLHQIDVLEDPAIRNVIV
LQTVLQEVRNRSAPVYKRIRDVTNNQEKHFYTFTNEHHRETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRN
KEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNE
ENKEIILQGLKHLNRAVHEDIVAVELLPKSQWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGML
SKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLS
FLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKSPNVH
NYPDMEAVPLLLNNVKGEPPEDSLSVDHFQTQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSRLASSPTVITSVSSA
SSSSTVLTPGPLVASASGVGGQQFLHIIHPVPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGRGHGKAQM
DPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSISPFSIESTRRQRRSESPDSRKRRI

--------------------------------------------------------------
>22898_22898_2_DIS3-KLF12_DIS3_chr13_73345932_ENST00000377767_KLF12_chr13_74420510_ENST00000377669_length(transcript)=12193nt_BP=1706nt
GGAATGGAAAGGGAAGAACCTCCGGGGTTAGGCGTATTCTAGATTGACGCCTTTTGCTGGAAGAGCGCTGCTGGGGTTAGGATTCTGCGC
GGCGAGGCAAGATGCTCAAGTCCAAGACGTTCTTAAAAAAGACCCGGGCGGGCGGCGTGATGAAGATCGTGCGCGAGCACTACCTGCGAG
ACGACATCGGCTGCGGTGCGCCCGGGTGCGCAGCGTGTGGAGGGGCGCACGAGGGGCCGGCCCTGGAGCCGCAGCCCCAGGACCCGGCGA
GCAGCGTCTGCCCGCAACCGCACTACTTGCTGCCCGACACTAATGTGTTACTGCACCAGATTGATGTTCTTGAGGACCCTGCCATCAGGA
ATGTAATTGTGCTACAAACAGTTCTTCAAGAAGTGAGAAATCGCAGTGCCCCCGTATATAAACGCATCCGAGATGTGACTAATAACCAAG
AGAAGCATTTCTATACTTTCACTAATGAGCACCATAGAGAAACCTATGTAGAACAAGAACAGGGAGAAAATGCTAATGACAGGAATGATA
GAGCGATTCGAGTAGCAGCAAAATGGTACAATGAACATTTGAAAAAAATGTCAGCAGACAACCAGCTGCAAGTTATCTTCATAACAAATG
ACAGGAGAAACAAAGAGAAAGCCATAGAAGAAGGAATACCAGCTTTCACTTGTGAAGAATATGTAAAGAGCCTAACTGCTAACCCCGAAC
TCATAGATCGTCTTGCTTGTTTGTCTGAAGAAGGGAATGAAATAGAAAGTGGAAAAATAATATTTTCAGAGCATCTTCCCTTAAGTAAGC
TACAGCAAGGCATAAAATCTGGTACATACCTTCAAGGAACATTTAGAGCTAGCAGGGAAAATTACTTGGAAGCTACAGTATGGATTCATG
GCGACAATGAAGAAAATAAAGAGATAATCTTACAGGGACTTAAACATTTAAACAGAGCTGTTCACGAAGATATTGTGGCTGTGGAGCTTC
TCCCCAAGAGTCAGTGGGTAGCACCATCTTCTGTGGTTTTACATGATGAAGGTCAAAATGAAGAAGATGTGGAGAAAGAAGAAGAGACAG
AACGAATGCTTAAGACTGCTGTAAGCGAGAAAATGTTGAAGCCTACAGGTAGAGTTGTAGGAATAATAAAAAGGAATTGGAGACCATATT
GTGGCATGCTTTCCAAGTCTGACATTAAGGAGTCAAGAAGACATCTCTTTACACCTGCTGATAAGAGAATCCCTCGAATTCGCATAGAAA
CCAGACAGGCTTCCACATTAGAAGGACGGAGAATTATTGTTGCTATTGATGGTTGGCCCAGAAATTCCAGATATCCAAATGGACACTTTG
TGAGAAATTTAGGTGATGTTGGAGAGAAAGAGACTGAAACAGAAGTTTTGTTACTTGAACACGATGTTCCCCATCAGCCTTTTTCACAGG
CTGTTCTTAGTTTTCTGCCAAAGATGCCCTGGAGCATTACTGAAAAGGACATGAAAAACCGAGAAGACCTGAGGCATCTGTGTATTTGTA
GTGTAGACCCACCAGGATGTACTGATATAGACGATGCTCTACATTGTCGAGAACTCGAAAATGGAAATTTGGAGGTTGGTGTTCATATTG
CTGATGTGAGCCATTTTATTAGGCCAGGAAATGCCTTGGATCAAGAATCAGCCAGAAGAGGAACAACTGTGTATCTTTGTGAAAAGTCTC
CAAACGTCCACAACTATCCCGATATGGAAGCCGTTCCCCTGTTGCTAAATAATGTGAAAGGGGAGCCCCCGGAGGACTCGTTATCTGTAG
ATCACTTCCAAACACAAACTGAGCCAGTGGACTTGTCAATAAACAAAGCCAGGACGTCCCCTACTGCCGTTTCATCCTCCCCAGTTTCCA
TGACAGCATCTGCCTCCTCACCTTCTTCAACTTCAACCTCTTCATCGTCTTCTAGTCGTCTAGCCTCATCCCCAACTGTTATCACATCAG
TATCTTCAGCGTCATCTTCGTCAACAGTATTAACTCCAGGGCCCCTTGTGGCCTCTGCATCTGGTGTTGGAGGCCAGCAGTTTTTGCACA
TTATCCATCCCGTACCGCCTTCAAGTCCCATGAATTTACAGTCTAACAAACTGAGTCATGTTCACCGCATCCCCGTGGTGGTACAGTCGG
TGCCTGTTGTCTACACAGCTGTAAGGTCACCTGGAAATGTGAACAACACTATTGTCGTGCCGCTTTTGGAGGATGGGAGAGGCCATGGCA
AAGCACAAATGGACCCCCGAGGCCTATCTCCCAGACAAAGTAAAAGTGACAGTGATGATGATGACCTGCCAAATGTGACCTTAGATAGCG
TTAATGAAACTGGATCTACGGCCCTTTCCATAGCCAGAGCAGTACAAGAGGTACATCCGTCCCCAGTATCAAGGGTCCGGGGCAATCGAA
TGAATAATCAAAAGTTTCCTTGTTCAATTTCACCATTTAGTATTGAGAGCACAAGACGCCAGAGACGGTCTGAATCCCCAGACTCCAGAA
AACGGCGTATCCACAGATGTGATTTTGAGGGATGCAACAAAGTGTACACAAAAAGTTCTCACCTGAAGGCTCACCGGAGGACACATACAG
GAGAGAAACCTTACAAGTGTACCTGGGAAGGCTGCACCTGGAAGTTCGCTCGTTCAGATGAACTGACGAGGCATTACCGCAAACATACGG
GAGTGAAGCCATTCAAGTGCGCGGACTGTGATCGCAGCTTTTCCCGGTCAGATCATTTGGCCCTGCACCGCCGGAGGCATATGTTGGTGT
GAGGAATGCTACCTGTCCAGCTGAGCGTAAGAGCTGGATCTCTTAGCGGCACCCAATTCAGCAGGGCTGAATCCCCTTCACAGTGTTAAC
ACAAAAGGGCATCACCATCCCACGATGTCTGAAACCAGAGCAGGAAAAAGAAGGCACACTTCTTTTGGTCTGAAGGTAACCCCCATCATG
ACTAGACGAGAACCGTCTTTACCCGGGCCTGGGAGCTCAGTGACATAAATGCTGAAGAGACAGGCATTGTTTTCCGTGCTGTGTCCTCTG
CCATTTAAAGATGTTTGTAGCTTGTACATTTTCTGAGCTGTCAGACATTTTGTTATTGATACCTTAAAGGTCACCTACCACAAATTGATG
GCTAGAGCAAGACCTTTTAAATTTGGATGAATCTCCCATCATCCCATCCCTTAACCCCTTTTTACAGAAATTTTAGTTACAATCTGAGTA
AGCTAGAACACACATCCAATCTGTTACCAGCAAGCAGCATGAAAGTAGAAACGAAGAAGCAGATGGAGAGGTCCCATTACCTGCAAAGAA
AGGGCACTCAGGCAGCCCTTTGCAATCGCGATGGCAGCCACTAGATATCACTCTCAACTTGTCATTCTGCCATGCCCTGAAGAAAACCAA
CATTGAATCTTTCATTTGTTTGTCGTTGATTGTTTTTGTTTTGTTTCGATTCTGTTTTGTTCATCTGTTCGAGCAGAGGGGCAGTTGAAG
TCTCGTCCTGGTCTCTGCCCTGGCATGGACTGGCACAGAGGTGTTCTGTAGTTGAATAGGAAGAGCCTGTCTAAAAAACTACTGCCCCAC
TTCAAATTGCAGTGTTCTGTCACCTAGGCATCATCTCTTCCTGCCCCTAGTATTTGATTACAAGGAACCAGGGGAAAAAAACTTTCTTAG
ACACACTGGCACCAAGGTAAGAGGTGGGGCTGCCCAGGCAAAGTCAGTGAACATGAAAACTCAGACAAAGCAGAGATGGAAATAATGCGC
CTCTTGAGGAGAAAAGCAATAATGAATAAAAGGACTTTCCTACAATAACTTCACTGAGGACTCACGTTACCAATTTTCATACTTACTAAA
GGGATTGTAAAAAACACCCCAGCATTTTAGGTGTCTTGGTTCCATTTACAGCACTGAGGTAATCTTTCTGCTGTTTGTTGTCCTGCTTGG
TTGAGTACCACAATTAAAGATTATGCTCCCCTTTTCTTGTTTGAAAACAGTTATTTGGTGACTAGAAAGGCAAGGGAGGCATAGCCGGGA
ATTAACTCTTCGGTTAATGGGTCAGTTCTCCTTGGAACTGAATCAGTGGAAAGAGAATGCTTCCCATAGAAAGCCCGACATGGTGCTAGT
TTCCTCTCTTGGAGAGCCAAGGATAAGTGACTCTCCAATAGGTTCTTCTATACCGATTTCATTTTCTAAACTGTATCAGGACCCAGGTGT
CCTGCATTGGCATCTGCAGGGATATTGAACCCACTCATCCTGTGCAGAGGATGAGAGGAAGGTGTTAGTTCCATCAGCCCCATAAAATTA
TGAACCTTTTTGCAACTAGGAACATATACAGTAAACAAGCAATACATCACCAACGAGCATTCTTTCAGAAAAATTACCATATTTTTGTCC
CCACCACAAGCTGGGTTTTTTTCCAGCTTTCTGTGGCTGAGGGGCTGGTGAGATTTTTTGTTGTTATTGTTGTTGTTGCTAGAATTTTTT
ATAGCTTAGATATAAAAGGTCTCCAACAAAGACCTTTGCAATATATTTTAATTACAAACACTTGATTTTGGGAATTGCACATATTAACCT
CACAATATTACTAGCTCATTTTTAAATGTCTGGACATTCTGAAATAATTTCCGGTTACAGAATTACCCTTTTTAGGATCATCTTCTAATT
CAGATAATCTTATTCTGATGAAGCGAGAACTATGAACGTTGAAACAAGGACAATTTGTGTTGGATGGTATTCAAAAGGAATTTTTTAAAA
CATTAAGCAACAGTGTAATGATTTTCAGGTCAAATTATGGCTTCACAAATATGTGCTCTATATTGTCTGCCAGGTCTCAAAAATTCATCA
AGCAATTTCCCTCCAACAAGGGCTGCAGTTCTAGTGATAAATAGCATCTTTAGCTGCACAGTCTACTACTCATCAACCAGTGGGTTTTTT
TTAGCACCTGGAAAGTTTTTTTGTACTATATGCAACTCCTACTTCACATTGCCTGTGACCATTCAGAATAGAAAAAGGTCTGTTGATGCA
TGCCAGTGCTGGTTACTAGTCAGTGACAGAGAACACAGAGAGGGACAAACACAGCCATGAACCCCCTGGCACTAGTACCAGCACCTAGTT
GGCAAGTAGTGGGTGCATCTCTCAAGTGAAGTGTAGATTTGTATTTAGTCCTGCTTGCTCTCATAAAAAGAGCCAGTTCTTTTCTCTGCT
GAAAGATGTCTTGAGAGTATTACAGGTAGACTTGGTTTTTAGAATTCATAAAACTGACAGGCAGGGGAATCTTCCTGAGTGACAGCTTGG
TTTAAATTTAGCACAGAACTAGATGAGTTGCACTTTTCTAATAACATAGGATGGATTTGGGGAAGGGAACATTTTCCCTCATCCTCTGAA
AGTGGAAACCAGACTGAGATGGTAAGTTAACTGATAAAACCTGTCAGCATTCCATCATTTTCCCCTTTTGACGTATCAGTACTTCTAAGA
AGGGATCTAAGCACAATTAAGTGAATTGAGTCCCTGGTCTAGCCTCAGGAACTGAAACTTCTTTGGGGCTTGTCTTGAGACGTGGCAAAT
TCTCCTTGGTGAGTTTTCTAAAAGTATTTCCCCATGGAAAGGAGAAAGTGGTTTGGGACAGAAAGAAATGGAATGTCTTCAGTCATGGAA
GAGCCTCCATTTCATCTCATGTCCATTTCTAGCCTCTTTCAAAAAGCACAGTGCATCATGAGCAACAGAAAAGCAGTAGAATCCTAAAGG
ACATAACAGTTGTTCCGTAACTAGAAGCATTCTTTGATTTTAAATTTGAAGCTGTTCAGTTTGCAGCTGGGGATATGTGCATGGTTGGGA
ACTTATACACATAGAGCCATTAACTACTTAAGCAGCTGCAGTAGACCTGATTTTCTGTTTGCAGTATAGAGATTGATTTCAAGGGAGTTA
CATTATTTGAAAAGTTATGACTTTCAGCCTTTGAGGTTTTAAGAATCCCTTTTCATGGTCTGATCTTAAGTTGTTTGAAAAAAGATTCAC
GCTTCTGCATCCACCTCTGCCCTCATTCTGTCAATTGTGTGTGGACTCTGAGAAGCCTGCTTGATAACTTGTCTTAAGTTCTATTAAGGC
AGTTAGACTGAGATTTCTAATGACTTCACCATAAAGATTATACTTCTGCCTGGCGTCGTTTCTATAAAACACTATAGGACATTTGTTTTC
AAAAGCAGTTGAGTAACAGCAACATAAACCACATTTTTTAAAAAAATGAGCACTTTTCATTCACTTGAAAGCTTAAGTGGGAAAAAGGAA
GATGATTGTCAGGGGAAAAACTTACAAAATGCTACAGTGTTTACAAATGCCAGTTCCAGGTGATTAGAAAGGCCGTTTTCATTATGGTTC
AGATTTGGAATAGCTTATGCAAAGATTGTGTTCATTTTTATACAATTCTTTTTAACTTTAAATTGCCATCTGTGTTTTAAACATAATTCT
GCACTTTGGAATCAGTTCATTAGAATGATAACATTTATATGGATAAAGATGCAGTATTCCTTATTCTGTACTTGATTTATTATACTTACC
AAAGCTGCAACTGAATAAATCTGGTGAGGTGAGGCCTTCAAAATGTATTAATACGCCTTTGTTATGTTGTTATGACTGCTTAGAAATGTA
GCCATGATGTTGTTCTAAAGATGTCTTAACATTTATAGTGAGGATTGACAGAAATTAAGCAGTGTTAAGAATACCAGCATCCATGTTACA
GTCTGCGTATAAGGGACTGAATGTGAGGTAACTCTTATGAATCATAATAGGCCCAGAAAGCCTTAATATTCATAGTTCATAATCCAGTCT
CAGATTTTGCTCTTCAATGTTGCCTGTAAACTTAGCAGGTAAATGTATTCTAGTATAAAACATCATTGACCAAATCTCTTCCTTTAGTTT
TTCTGAGGTAGTGCATCCCATTAAAAAAGTCTCTTCAATTAGATTTGGCTTTAGTTTAGAAAGGGGTTTGGTAAGTCATGTCTTCCATAT
GACATTTCTACTCATCCCCACACTGCCTTCCACTTAACCTGTACAGACAGCCCCAACACATGCACATGTGTGTACACAACTGTATATGCA
GCAGCCAGTGGGCTAACAAATATCAGCAAAGAACTTTTTTAAAAAGAATTTGTAATAATCCGTGCTGTCTAGAAATGTGAGTTACTTACC
TTATTAGGAAACCGGCTTATAATACTATATATGACTCTGCCTGCATTTTATAGTTAAGAAATGTACATAAAAATTGCTATATTTTCACAG
TTTCATTATAATGTCTGTTTAGTAACCCATGTCCACTGATACTTTAAATATGCTAATTACTGAGCAATTGCAATAGAAATCCAGATTTTC
ATAAGAAAATGAAATAGAAGGATACTGCATCTTTAAAAAATAGAGTGAAGATATTTTACTGTATTCGTAACATATGTGATAGTGGAAAAA
GTATTTTCAAACTCACAAATTTTACAGAGGTTGTAAATAGTTTGATGAAGTATGTTGGGAAAGAGAGCTTCTAGTTTTCATCACAATAAA
AAGAAAAAACTTGTTCAGATATGCCTTGTATATCTTACACACAATGAGTGAAATTGCCATGGGAACTCTGTCCAACTTTGTCAGAGCATG
CTCTTCGTGTTCTGTTCAAAATAGAGTGGCCACTTGTCATGGTTTAGCCAGGATGGTTTAAAATATAATGAAGTCATTTTAAGTTGCAGA
CAACTGATTCCAAACTAGTAATGTCTTTTCCTGAAAAGGGCAAAACAGCTGCACAGGATTTTGCTTGTACTAAAGAGGAGCATCTTACAA
TTGTTCTCTTTTCTCAGTTATCTCCCTCCTCAACAGAGTGTGAACAACCATACAGGTGTTTATTCTTGTTTTATTCCAGGGAGACTGCTT
TTAGGTATAACTACATGTTGACAAGATTAAGTGCTGTGGATATGGCCACGTGTTAAAGGAATCTATACTCGCAATAGGAATAAGCTAATG
CCCATTTTCAGAAATAAATTAAATGCTGAAAGTGCCTGTCAGTAAACCTTATGACCAATGAGATATTCCTATACTTTTACACAGCAATAA
TTCTTAATAAGACTGGGTTTTTTCCTGCACATGTGAACACACACACACATACACACAGAGAGAGTAAATACATACACATAGTAAATCAAA
TCTGTTCACATGCCCACAAAAAACGCTTTTATAGCTTTCAAATATACCTAATCTTGTTTACATTAACATTTCTTAATTTGATCTTTCTAA
CTTGCAGAACGTTAAGAACACAAATCTGAACATTAAGTTTATCTTCAGTGAACACTATTGCATATGGTAATTATAATTTCCAGATAAAAA
GTTGACTGTCATTTGCCCCAAACTTATGAAACAGTATGTATGATTCAAAAAGTTTTGCTCAGTTAAAAACACCAATTTATTTGGCGCAAA
AGACTGAAGGATATTTGTTTGCTTGTTCATTTTATCCACTCATATCAAACGCACAAATTCATCTTTACATTTCTTCATTCCCCTTTCCCC
TAATATTTCCTATTATCATCTTAAGAATCATTTTGGAATGAATATTGACAGAATCATTTCTCCCCAAAAAGTCTGTTGAAGTACCACTGA
CACTTAGTAAGCCTAGCCTTTAACCATCTTTGCAGTTAGTCCTAAAAATTACCAGATGCACATTCAGAAGCTCACAGGTTTTTTCCTGTA
ATTACTGTACTGCTAAAAGTGGAGTCATGGATAGAAATATACAATGAGACTATATGAATAGACATGAACCCTGGAAATTCTCCAACCCTG
CCATCTCAGAGCACAAATTCACCCAAACAAGCTACTGAGGCTATCAGTAAAATTATACTCATGGAGAGTCACACATCGGGTAAGGGCAAT
TTTAAAAGTAGGACTGTGATTAAACATTCAGGCTTTAGACTTCCATGATGGACTCAGACCACAGGCCTCAAAAAAACATCCACTGTTTTC
TCCTCCCAATGTTAGAAAGAAGAAAAGGGAGACGGAAATGTACCAGGATAAGGGGGTAAAATAACCAATTAAGTGTCAAAGGAAAGCTGC
TGGGTTCCTTAATCTCACTGAAGTCAAGTCTTCTGACTGGGCTTCTTACCATGTGTTGTCTGAAAAAACTAAAGTACCTTGAAAGGTTAC
ACATTCAGCAAACCATGAAGATAATAGCTATTCTTTATTAAACACTGTGTGCCAAGCAATAGACTAGGCAATTTTTAGATACGTTACCTG
CAACCTGTACAACATTTCTACACTTTATGGATGGGAAACGGAGACATGGGAAGTGTGGCTGAGTTGTTCATGGATGTAGAAATAGTAAAC
GGCAGAGTAGGAAAGTGAAACCGCCTATCTCTGACCTGGAGGTCTGCCTGTATCTTTCCCACTCCACCACACTGCACGTGGGTGTCCCGA
AACCACCTTCCCAGATTCCTGACTCTCAGTAATTTTATTATGGACAACATGCATGAGTAGTCATCATATTTTTCAAGTGAAATATCGGGA
CATGATATAACACATGACTTAACAATGGTACTGAATATTTGAAATCAGGCCTTTCCCGGAAAATCATGCATGAAGGATCATTATAAACAA
ACAATAGCAACCAGTTGTCTCCCCGAACTTGTCACTTTTCTCATAAATGTCTGGCCTGGAGCTCCAAAATCATCCAAATACTTAGTAGCA
TTTTAGCCTGAGTACACTTTCTCAGTTCCTCAACTCTTTGTATACCTTTCCACCAATATAGACATTCTAGAATCTGCTTCAGATGCATTT
GAAATTTTCACCCCCATGGAACTAGTGATTAATATCAGAGCCCACTCTTGCAGTTGGTAATGGGGTGGCAATCAAACGTTCAGATGATGA
TAAAGGAGAGATAATGGATAATTCTTTTTCAGAGTTCTCACTTAACAGCTCTGTTGTGGAATGTTTTAAATAGTCTTATAAATAATTTGT
TTATAGTATTGTTGTTAGTTTAATTGAATTTTATGTAAGAAGCTGTCCAACATCAGAGAAATGAAATTCCTCCCACTTTCTGTGTAGAAC
AAGGTCTCTGACAGTATTGATTCATGGAAGTACTAATGGACTTAGAAAACATTAAGAGAATGTCATTTCTCATAGTGTTTCTGTTTCTGA
AAATGAATCTCCTGAATTATTATCTTTCTCCCTGTTACTTGGCTGGGGAAAGAGATAGAAGCTGTATAAACAAATTCTCTTCCATGCTCA
AAGCAAGTGTTCCATGTGCACAACCTGCTGCAGACTGGGGCCCTTCTCAGTTAATTGGGTTTCACAAGCAATAATTTCTCCACAACAAAA
ACCACAACTTGAAGTGAGTTGAAAAGAGATCAATAGTGGAAACAGTCGCCTCAGTACTTTTTCTTTCTGGATTTCATCTCTAGAAATTTG
AAGTGTTTGAGACAGAGTCCACCCTTTGTGCAAGGCGAGAACCAATGAATGGACTCCTTGTGTGAATTATTGCATCTTCTTCCAAAGCAG
GTTCATCAAGACTTTCACAGAGATTCATTTTTGTTGAGAAGTAAGGGTTAATAGGAGGATAGAATTTGGATCCAAATCTAGTGATAAAAG
TGTCCAAGCAATCAAAAAGTAAGATATTTTAGGGACATACCAACATCTTCCCTTTCTGCTAATTTCATGCTCCAAAGATATGGCAAAAAA
AAAAATCATAAAAAGTGCTTTTGCCCTACTTGTGTTCTAGTTTTCCCATGGCAGAATTTTGTAATTACATCCAGAATATAGTGTATATTT
TGTTCCTCAAACTTTATTACATTGGATGGATATTGTTGAACTGGGGCACTGGTGCCTATATTCAAGGCTCTTTCCTATCAACGTGTCTGT
CCACGATTTGTTGTGTTTAAAGCTTCATTTTGAAAAATCACTGTCCCCCTGTGGGGTAGTGACTGTATTGTTTTGTTCATGTCTATGTGG
GACACATTGCATCACATGGCAAACCAACTCTCTGTGGATGTGAGATAAGTACTTATAAAACCAGCTTGAAAACATCGTCTTATGTATTAT
GTCATCCTGCATCATAATGCAATTATGTGTATCATAACATGCTCATTTAAAAAAAGAGAAACCAGCAAATTCATGTTTGTCCATAGAAGA
ATGTACTCAGAACTTTGTGTTGTGAAACGATGAGAACAGACCACCTTTAAGATACCCACCTGCCACTTAAAATGACTTAGTTATAATTAG
TAGTAGTCTAGACGTTGTTCTTGGTGTGTGGGGGTCAATTCTAACGTCATGTTCTTTTGAATAAATCTCTCAGTCATATTTGAAAAAAAA
ATACATGGGAATAAAGAAAAATATCATCTTTGGCCAAATCAAGCAGGCATCTTTTTTCTTTTCCTTGACGTTTAGCTCATTATACGTGGT
GATTGGATCACGAGATCTGTCCGTGTGAAAATACAGAAACATCCTTTAGTTTACAAAACAGTTATTCTAGGCTTGAAGCCTCTGAACAGC
AAATTGAATAGATGGGCTGCATCTGATTTGCTTTATGGATGTAATTTTACAAAACACTCTTGGGTCTCTGACCCCAGGGAGTTAAGAGTG
CCCAGAGGAGGTCCTACACATTAAAGGATAAAGCCCCCCAGTGATGCTGGCAAGCAAATGTGTTGAGTTCTTAAATCTTCATTTGGTTTT
CTGTTCAGGATTTTAATTGCAAATGAATTTATTTCTCCAGTTTATCTAAAGACCTAATTTCCCAATAGTTTCCTCTGCATTTATATACTC
TGTAGTGTTTAGGCAACCCTGTTATAAGTTTATTAATATTATGTAAGTGTTGTTCTTGTATTTATGTATAGTGTATGTATTGTAAATATA
CTCAGAGCTTTTTTCCTTTTACTGTAAAATGGTGATTTTTTTGCCCTATGATAATGTAAAGGGAGACCCTCCTAATGAGATTCTCTCAGA
GGATGATTATTCCAGTCTATTCTCAGAGATTTAAATGAACAAGTGTTATTGTTTTTAATGGTGTCTCAGACATATTCTGTTGGTGCATTG
CTTTTCTGTATTCAACTTTCCTATGAATTGAGCTGTGAACTGAAATAGAGTTTAAACCTTTAACTGTATGCATTTGTATAATTATCTGAA

>22898_22898_2_DIS3-KLF12_DIS3_chr13_73345932_ENST00000377767_KLF12_chr13_74420510_ENST00000377669_length(amino acids)=896AA_BP=535
MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVCPQPHYLLPDTNVLLHQIDVLEDPAIRNVIV
LQTVLQEVRNRSAPVYKRIRDVTNNQEKHFYTFTNEHHRETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRN
KEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNE
ENKEIILQGLKHLNRAVHEDIVAVELLPKSQWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGML
SKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLS
FLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKSPNVH
NYPDMEAVPLLLNNVKGEPPEDSLSVDHFQTQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSRLASSPTVITSVSSA
SSSSTVLTPGPLVASASGVGGQQFLHIIHPVPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGRGHGKAQM
DPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSISPFSIESTRRQRRSESPDSRKRRI

--------------------------------------------------------------
>22898_22898_3_DIS3-KLF12_DIS3_chr13_73345932_ENST00000377780_KLF12_chr13_74420510_ENST00000377666_length(transcript)=2785nt_BP=1608nt
AAGGGAAGAACCTCCGGGGTTAGGCGTATTCTAGATTGACGCCTTTTGCTGGAAGAGCGCTGCTGGGGTTAGGATTCTGCGCGGCGAGGC
AAGATGCTCAAGTCCAAGACGTTCTTAAAAAAGACCCGGGCGGGCGGCGTGATGAAGATCGTGCGCGAGCACTACCTGCGAGACGACATC
GGCTGCGGTGCGCCCGGGTGCGCAGCGTGTGGAGGGGCGCACGAGGGGCCGGCCCTGGAGCCGCAGCCCCAGGACCCGGCGAGCAGCGTC
TGCCCGCAACCGCACTACTTGCTGCCCGACACTAATGTGTTACTGCACCAGATTGTAAGTGCCTGGAGGCCGGGGACCTGGGCTTCTGTG
GCCTCCAGCCTGCGACTCCCAGGCAGCTTAGAAACCTATGTAGAACAAGAACAGGGAGAAAATGCTAATGACAGGAATGATAGAGCGATT
CGAGTAGCAGCAAAATGGTACAATGAACATTTGAAAAAAATGTCAGCAGACAACCAGCTGCAAGTTATCTTCATAACAAATGACAGGAGA
AACAAAGAGAAAGCCATAGAAGAAGGAATACCAGCTTTCACTTGTGAAGAATATGTAAAGAGCCTAACTGCTAACCCCGAACTCATAGAT
CGTCTTGCTTGTTTGTCTGAAGAAGGGAATGAAATAGAAAGTGGAAAAATAATATTTTCAGAGCATCTTCCCTTAAGTAAGCTACAGCAA
GGCATAAAATCTGGTACATACCTTCAAGGAACATTTAGAGCTAGCAGGGAAAATTACTTGGAAGCTACAGTATGGATTCATGGCGACAAT
GAAGAAAATAAAGAGATAATCTTACAGGGACTTAAACATTTAAACAGAGCTGTTCACGAAGATATTGTGGCTGTGGAGCTTCTCCCCAAG
AGTCAGTGGGTAGCACCATCTTCTGTGGTTTTACATGATGAAGGTCAAAATGAAGAAGATGTGGAGAAAGAAGAAGAGACAGAACGAATG
CTTAAGACTGCTGTAAGCGAGAAAATGTTGAAGCCTACAGGTAGAGTTGTAGGAATAATAAAAAGGAATTGGAGACCATATTGTGGCATG
CTTTCCAAGTCTGACATTAAGGAGTCAAGAAGACATCTCTTTACACCTGCTGATAAGAGAATCCCTCGAATTCGCATAGAAACCAGACAG
GCTTCCACATTAGAAGGACGGAGAATTATTGTTGCTATTGATGGTTGGCCCAGAAATTCCAGATATCCAAATGGACACTTTGTGAGAAAT
TTAGGTGATGTTGGAGAGAAAGAGACTGAAACAGAAGTTTTGTTACTTGAACACGATGTTCCCCATCAGCCTTTTTCACAGGCTGTTCTT
AGTTTTCTGCCAAAGATGCCCTGGAGCATTACTGAAAAGGACATGAAAAACCGAGAAGACCTGAGGCATCTGTGTATTTGTAGTGTAGAC
CCACCAGGATGTACTGATATAGACGATGCTCTACATTGTCGAGAACTCGAAAATGGAAATTTGGAGGTTGGTGTTCATATTGCTGATGTG
AGCCATTTTATTAGGCCAGGAAATGCCTTGGATCAAGAATCAGCCAGAAGAGGAACAACTGTGTATCTTTGTGAAAAGTCTCCAAACGTC
CACAACTATCCCGATATGGAAGCCGTTCCCCTGTTGCTAAATAATGTGAAAGGGGAGCCCCCGGAGGACTCGTTATCTGTAGATCACTTC
CAAACACAAACTGAGCCAGTGGACTTGTCAATAAACAAAGCCAGGACGTCCCCTACTGCCGTTTCATCCTCCCCAGTTTCCATGACAGCA
TCTGCCTCCTCACCTTCTTCAACTTCAACCTCTTCATCGTCTTCTAGTCGTCTAGCCTCATCCCCAACTGTTATCACATCAGTATCTTCA
GCGTCATCTTCGTCAACAGTATTAACTCCAGGGCCCCTTGTGGCCTCTGCATCTGGTGTTGGAGGCCAGCAGTTTTTGCACATTATCCAT
CCCGTACCGCCTTCAAGTCCCATGAATTTACAGTCTAACAAACTGAGTCATGTTCACCGCATCCCCGTGGTGGTACAGTCGGTGCCTGTT
GTCTACACAGCTGTAAGGTCACCTGGAAATGTGAACAACACTATTGTCGTGCCGCTTTTGGAGGATGGGAGAGGCCATGGCAAAGCACAA
ATGGACCCCCGAGGCCTATCTCCCAGACAAAGTAAAAGTGACAGTGATGATGATGACCTGCCAAATGTGACCTTAGATAGCGTTAATGAA
ACTGGATCTACGGCCCTTTCCATAGCCAGAGCAGTACAAGAGGTACATCCGTCCCCAGTATCAAGGGTCCGGGGCAATCGAATGAATAAT
CAAAAGTTTCCTTGTTCAATTTCACCATTTAGTATTGAGAGCACAAGACGCCAGAGACGGTCTGAATCCCCAGACTCCAGAAAACGGCGT
ATCCACAGATGTGATTTTGAGGGATGCAACAAAGTGTACACAAAAAGTTCTCACCTGAAGGCTCACCGGAGGACACATACAGGAGAGAAA
CCTTACAAGTGTACCTGGGAAGGCTGCACCTGGAAGTTCGCTCGTTCAGATGAACTGACGAGGCATTACCGCAAACATACGGGAGTGAAG
CCATTCAAGTGCGCGGACTGTGATCGCAGCTTTTCCCGGTCAGATCATTTGGCCCTGCACCGCCGGAGGCATATGTTGGTGTGAGGAATG

>22898_22898_3_DIS3-KLF12_DIS3_chr13_73345932_ENST00000377780_KLF12_chr13_74420510_ENST00000377666_length(amino acids)=866AA_BP=505
MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVCPQPHYLLPDTNVLLHQIVSAWRPGTWASVA
SSLRLPGSLETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRNKEKAIEEGIPAFTCEEYVKSLTANPELIDR
LACLSEEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLNRAVHEDIVAVELLPKS
QWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQA
STLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDP
PGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKSPNVHNYPDMEAVPLLLNNVKGEPPEDSLSVDHFQ
TQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSRLASSPTVITSVSSASSSSTVLTPGPLVASASGVGGQQFLHIIHP
VPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGRGHGKAQMDPRGLSPRQSKSDSDDDDLPNVTLDSVNET
GSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKP

--------------------------------------------------------------
>22898_22898_4_DIS3-KLF12_DIS3_chr13_73345932_ENST00000377780_KLF12_chr13_74420510_ENST00000377669_length(transcript)=12095nt_BP=1608nt
AAGGGAAGAACCTCCGGGGTTAGGCGTATTCTAGATTGACGCCTTTTGCTGGAAGAGCGCTGCTGGGGTTAGGATTCTGCGCGGCGAGGC
AAGATGCTCAAGTCCAAGACGTTCTTAAAAAAGACCCGGGCGGGCGGCGTGATGAAGATCGTGCGCGAGCACTACCTGCGAGACGACATC
GGCTGCGGTGCGCCCGGGTGCGCAGCGTGTGGAGGGGCGCACGAGGGGCCGGCCCTGGAGCCGCAGCCCCAGGACCCGGCGAGCAGCGTC
TGCCCGCAACCGCACTACTTGCTGCCCGACACTAATGTGTTACTGCACCAGATTGTAAGTGCCTGGAGGCCGGGGACCTGGGCTTCTGTG
GCCTCCAGCCTGCGACTCCCAGGCAGCTTAGAAACCTATGTAGAACAAGAACAGGGAGAAAATGCTAATGACAGGAATGATAGAGCGATT
CGAGTAGCAGCAAAATGGTACAATGAACATTTGAAAAAAATGTCAGCAGACAACCAGCTGCAAGTTATCTTCATAACAAATGACAGGAGA
AACAAAGAGAAAGCCATAGAAGAAGGAATACCAGCTTTCACTTGTGAAGAATATGTAAAGAGCCTAACTGCTAACCCCGAACTCATAGAT
CGTCTTGCTTGTTTGTCTGAAGAAGGGAATGAAATAGAAAGTGGAAAAATAATATTTTCAGAGCATCTTCCCTTAAGTAAGCTACAGCAA
GGCATAAAATCTGGTACATACCTTCAAGGAACATTTAGAGCTAGCAGGGAAAATTACTTGGAAGCTACAGTATGGATTCATGGCGACAAT
GAAGAAAATAAAGAGATAATCTTACAGGGACTTAAACATTTAAACAGAGCTGTTCACGAAGATATTGTGGCTGTGGAGCTTCTCCCCAAG
AGTCAGTGGGTAGCACCATCTTCTGTGGTTTTACATGATGAAGGTCAAAATGAAGAAGATGTGGAGAAAGAAGAAGAGACAGAACGAATG
CTTAAGACTGCTGTAAGCGAGAAAATGTTGAAGCCTACAGGTAGAGTTGTAGGAATAATAAAAAGGAATTGGAGACCATATTGTGGCATG
CTTTCCAAGTCTGACATTAAGGAGTCAAGAAGACATCTCTTTACACCTGCTGATAAGAGAATCCCTCGAATTCGCATAGAAACCAGACAG
GCTTCCACATTAGAAGGACGGAGAATTATTGTTGCTATTGATGGTTGGCCCAGAAATTCCAGATATCCAAATGGACACTTTGTGAGAAAT
TTAGGTGATGTTGGAGAGAAAGAGACTGAAACAGAAGTTTTGTTACTTGAACACGATGTTCCCCATCAGCCTTTTTCACAGGCTGTTCTT
AGTTTTCTGCCAAAGATGCCCTGGAGCATTACTGAAAAGGACATGAAAAACCGAGAAGACCTGAGGCATCTGTGTATTTGTAGTGTAGAC
CCACCAGGATGTACTGATATAGACGATGCTCTACATTGTCGAGAACTCGAAAATGGAAATTTGGAGGTTGGTGTTCATATTGCTGATGTG
AGCCATTTTATTAGGCCAGGAAATGCCTTGGATCAAGAATCAGCCAGAAGAGGAACAACTGTGTATCTTTGTGAAAAGTCTCCAAACGTC
CACAACTATCCCGATATGGAAGCCGTTCCCCTGTTGCTAAATAATGTGAAAGGGGAGCCCCCGGAGGACTCGTTATCTGTAGATCACTTC
CAAACACAAACTGAGCCAGTGGACTTGTCAATAAACAAAGCCAGGACGTCCCCTACTGCCGTTTCATCCTCCCCAGTTTCCATGACAGCA
TCTGCCTCCTCACCTTCTTCAACTTCAACCTCTTCATCGTCTTCTAGTCGTCTAGCCTCATCCCCAACTGTTATCACATCAGTATCTTCA
GCGTCATCTTCGTCAACAGTATTAACTCCAGGGCCCCTTGTGGCCTCTGCATCTGGTGTTGGAGGCCAGCAGTTTTTGCACATTATCCAT
CCCGTACCGCCTTCAAGTCCCATGAATTTACAGTCTAACAAACTGAGTCATGTTCACCGCATCCCCGTGGTGGTACAGTCGGTGCCTGTT
GTCTACACAGCTGTAAGGTCACCTGGAAATGTGAACAACACTATTGTCGTGCCGCTTTTGGAGGATGGGAGAGGCCATGGCAAAGCACAA
ATGGACCCCCGAGGCCTATCTCCCAGACAAAGTAAAAGTGACAGTGATGATGATGACCTGCCAAATGTGACCTTAGATAGCGTTAATGAA
ACTGGATCTACGGCCCTTTCCATAGCCAGAGCAGTACAAGAGGTACATCCGTCCCCAGTATCAAGGGTCCGGGGCAATCGAATGAATAAT
CAAAAGTTTCCTTGTTCAATTTCACCATTTAGTATTGAGAGCACAAGACGCCAGAGACGGTCTGAATCCCCAGACTCCAGAAAACGGCGT
ATCCACAGATGTGATTTTGAGGGATGCAACAAAGTGTACACAAAAAGTTCTCACCTGAAGGCTCACCGGAGGACACATACAGGAGAGAAA
CCTTACAAGTGTACCTGGGAAGGCTGCACCTGGAAGTTCGCTCGTTCAGATGAACTGACGAGGCATTACCGCAAACATACGGGAGTGAAG
CCATTCAAGTGCGCGGACTGTGATCGCAGCTTTTCCCGGTCAGATCATTTGGCCCTGCACCGCCGGAGGCATATGTTGGTGTGAGGAATG
CTACCTGTCCAGCTGAGCGTAAGAGCTGGATCTCTTAGCGGCACCCAATTCAGCAGGGCTGAATCCCCTTCACAGTGTTAACACAAAAGG
GCATCACCATCCCACGATGTCTGAAACCAGAGCAGGAAAAAGAAGGCACACTTCTTTTGGTCTGAAGGTAACCCCCATCATGACTAGACG
AGAACCGTCTTTACCCGGGCCTGGGAGCTCAGTGACATAAATGCTGAAGAGACAGGCATTGTTTTCCGTGCTGTGTCCTCTGCCATTTAA
AGATGTTTGTAGCTTGTACATTTTCTGAGCTGTCAGACATTTTGTTATTGATACCTTAAAGGTCACCTACCACAAATTGATGGCTAGAGC
AAGACCTTTTAAATTTGGATGAATCTCCCATCATCCCATCCCTTAACCCCTTTTTACAGAAATTTTAGTTACAATCTGAGTAAGCTAGAA
CACACATCCAATCTGTTACCAGCAAGCAGCATGAAAGTAGAAACGAAGAAGCAGATGGAGAGGTCCCATTACCTGCAAAGAAAGGGCACT
CAGGCAGCCCTTTGCAATCGCGATGGCAGCCACTAGATATCACTCTCAACTTGTCATTCTGCCATGCCCTGAAGAAAACCAACATTGAAT
CTTTCATTTGTTTGTCGTTGATTGTTTTTGTTTTGTTTCGATTCTGTTTTGTTCATCTGTTCGAGCAGAGGGGCAGTTGAAGTCTCGTCC
TGGTCTCTGCCCTGGCATGGACTGGCACAGAGGTGTTCTGTAGTTGAATAGGAAGAGCCTGTCTAAAAAACTACTGCCCCACTTCAAATT
GCAGTGTTCTGTCACCTAGGCATCATCTCTTCCTGCCCCTAGTATTTGATTACAAGGAACCAGGGGAAAAAAACTTTCTTAGACACACTG
GCACCAAGGTAAGAGGTGGGGCTGCCCAGGCAAAGTCAGTGAACATGAAAACTCAGACAAAGCAGAGATGGAAATAATGCGCCTCTTGAG
GAGAAAAGCAATAATGAATAAAAGGACTTTCCTACAATAACTTCACTGAGGACTCACGTTACCAATTTTCATACTTACTAAAGGGATTGT
AAAAAACACCCCAGCATTTTAGGTGTCTTGGTTCCATTTACAGCACTGAGGTAATCTTTCTGCTGTTTGTTGTCCTGCTTGGTTGAGTAC
CACAATTAAAGATTATGCTCCCCTTTTCTTGTTTGAAAACAGTTATTTGGTGACTAGAAAGGCAAGGGAGGCATAGCCGGGAATTAACTC
TTCGGTTAATGGGTCAGTTCTCCTTGGAACTGAATCAGTGGAAAGAGAATGCTTCCCATAGAAAGCCCGACATGGTGCTAGTTTCCTCTC
TTGGAGAGCCAAGGATAAGTGACTCTCCAATAGGTTCTTCTATACCGATTTCATTTTCTAAACTGTATCAGGACCCAGGTGTCCTGCATT
GGCATCTGCAGGGATATTGAACCCACTCATCCTGTGCAGAGGATGAGAGGAAGGTGTTAGTTCCATCAGCCCCATAAAATTATGAACCTT
TTTGCAACTAGGAACATATACAGTAAACAAGCAATACATCACCAACGAGCATTCTTTCAGAAAAATTACCATATTTTTGTCCCCACCACA
AGCTGGGTTTTTTTCCAGCTTTCTGTGGCTGAGGGGCTGGTGAGATTTTTTGTTGTTATTGTTGTTGTTGCTAGAATTTTTTATAGCTTA
GATATAAAAGGTCTCCAACAAAGACCTTTGCAATATATTTTAATTACAAACACTTGATTTTGGGAATTGCACATATTAACCTCACAATAT
TACTAGCTCATTTTTAAATGTCTGGACATTCTGAAATAATTTCCGGTTACAGAATTACCCTTTTTAGGATCATCTTCTAATTCAGATAAT
CTTATTCTGATGAAGCGAGAACTATGAACGTTGAAACAAGGACAATTTGTGTTGGATGGTATTCAAAAGGAATTTTTTAAAACATTAAGC
AACAGTGTAATGATTTTCAGGTCAAATTATGGCTTCACAAATATGTGCTCTATATTGTCTGCCAGGTCTCAAAAATTCATCAAGCAATTT
CCCTCCAACAAGGGCTGCAGTTCTAGTGATAAATAGCATCTTTAGCTGCACAGTCTACTACTCATCAACCAGTGGGTTTTTTTTAGCACC
TGGAAAGTTTTTTTGTACTATATGCAACTCCTACTTCACATTGCCTGTGACCATTCAGAATAGAAAAAGGTCTGTTGATGCATGCCAGTG
CTGGTTACTAGTCAGTGACAGAGAACACAGAGAGGGACAAACACAGCCATGAACCCCCTGGCACTAGTACCAGCACCTAGTTGGCAAGTA
GTGGGTGCATCTCTCAAGTGAAGTGTAGATTTGTATTTAGTCCTGCTTGCTCTCATAAAAAGAGCCAGTTCTTTTCTCTGCTGAAAGATG
TCTTGAGAGTATTACAGGTAGACTTGGTTTTTAGAATTCATAAAACTGACAGGCAGGGGAATCTTCCTGAGTGACAGCTTGGTTTAAATT
TAGCACAGAACTAGATGAGTTGCACTTTTCTAATAACATAGGATGGATTTGGGGAAGGGAACATTTTCCCTCATCCTCTGAAAGTGGAAA
CCAGACTGAGATGGTAAGTTAACTGATAAAACCTGTCAGCATTCCATCATTTTCCCCTTTTGACGTATCAGTACTTCTAAGAAGGGATCT
AAGCACAATTAAGTGAATTGAGTCCCTGGTCTAGCCTCAGGAACTGAAACTTCTTTGGGGCTTGTCTTGAGACGTGGCAAATTCTCCTTG
GTGAGTTTTCTAAAAGTATTTCCCCATGGAAAGGAGAAAGTGGTTTGGGACAGAAAGAAATGGAATGTCTTCAGTCATGGAAGAGCCTCC
ATTTCATCTCATGTCCATTTCTAGCCTCTTTCAAAAAGCACAGTGCATCATGAGCAACAGAAAAGCAGTAGAATCCTAAAGGACATAACA
GTTGTTCCGTAACTAGAAGCATTCTTTGATTTTAAATTTGAAGCTGTTCAGTTTGCAGCTGGGGATATGTGCATGGTTGGGAACTTATAC
ACATAGAGCCATTAACTACTTAAGCAGCTGCAGTAGACCTGATTTTCTGTTTGCAGTATAGAGATTGATTTCAAGGGAGTTACATTATTT
GAAAAGTTATGACTTTCAGCCTTTGAGGTTTTAAGAATCCCTTTTCATGGTCTGATCTTAAGTTGTTTGAAAAAAGATTCACGCTTCTGC
ATCCACCTCTGCCCTCATTCTGTCAATTGTGTGTGGACTCTGAGAAGCCTGCTTGATAACTTGTCTTAAGTTCTATTAAGGCAGTTAGAC
TGAGATTTCTAATGACTTCACCATAAAGATTATACTTCTGCCTGGCGTCGTTTCTATAAAACACTATAGGACATTTGTTTTCAAAAGCAG
TTGAGTAACAGCAACATAAACCACATTTTTTAAAAAAATGAGCACTTTTCATTCACTTGAAAGCTTAAGTGGGAAAAAGGAAGATGATTG
TCAGGGGAAAAACTTACAAAATGCTACAGTGTTTACAAATGCCAGTTCCAGGTGATTAGAAAGGCCGTTTTCATTATGGTTCAGATTTGG
AATAGCTTATGCAAAGATTGTGTTCATTTTTATACAATTCTTTTTAACTTTAAATTGCCATCTGTGTTTTAAACATAATTCTGCACTTTG
GAATCAGTTCATTAGAATGATAACATTTATATGGATAAAGATGCAGTATTCCTTATTCTGTACTTGATTTATTATACTTACCAAAGCTGC
AACTGAATAAATCTGGTGAGGTGAGGCCTTCAAAATGTATTAATACGCCTTTGTTATGTTGTTATGACTGCTTAGAAATGTAGCCATGAT
GTTGTTCTAAAGATGTCTTAACATTTATAGTGAGGATTGACAGAAATTAAGCAGTGTTAAGAATACCAGCATCCATGTTACAGTCTGCGT
ATAAGGGACTGAATGTGAGGTAACTCTTATGAATCATAATAGGCCCAGAAAGCCTTAATATTCATAGTTCATAATCCAGTCTCAGATTTT
GCTCTTCAATGTTGCCTGTAAACTTAGCAGGTAAATGTATTCTAGTATAAAACATCATTGACCAAATCTCTTCCTTTAGTTTTTCTGAGG
TAGTGCATCCCATTAAAAAAGTCTCTTCAATTAGATTTGGCTTTAGTTTAGAAAGGGGTTTGGTAAGTCATGTCTTCCATATGACATTTC
TACTCATCCCCACACTGCCTTCCACTTAACCTGTACAGACAGCCCCAACACATGCACATGTGTGTACACAACTGTATATGCAGCAGCCAG
TGGGCTAACAAATATCAGCAAAGAACTTTTTTAAAAAGAATTTGTAATAATCCGTGCTGTCTAGAAATGTGAGTTACTTACCTTATTAGG
AAACCGGCTTATAATACTATATATGACTCTGCCTGCATTTTATAGTTAAGAAATGTACATAAAAATTGCTATATTTTCACAGTTTCATTA
TAATGTCTGTTTAGTAACCCATGTCCACTGATACTTTAAATATGCTAATTACTGAGCAATTGCAATAGAAATCCAGATTTTCATAAGAAA
ATGAAATAGAAGGATACTGCATCTTTAAAAAATAGAGTGAAGATATTTTACTGTATTCGTAACATATGTGATAGTGGAAAAAGTATTTTC
AAACTCACAAATTTTACAGAGGTTGTAAATAGTTTGATGAAGTATGTTGGGAAAGAGAGCTTCTAGTTTTCATCACAATAAAAAGAAAAA
ACTTGTTCAGATATGCCTTGTATATCTTACACACAATGAGTGAAATTGCCATGGGAACTCTGTCCAACTTTGTCAGAGCATGCTCTTCGT
GTTCTGTTCAAAATAGAGTGGCCACTTGTCATGGTTTAGCCAGGATGGTTTAAAATATAATGAAGTCATTTTAAGTTGCAGACAACTGAT
TCCAAACTAGTAATGTCTTTTCCTGAAAAGGGCAAAACAGCTGCACAGGATTTTGCTTGTACTAAAGAGGAGCATCTTACAATTGTTCTC
TTTTCTCAGTTATCTCCCTCCTCAACAGAGTGTGAACAACCATACAGGTGTTTATTCTTGTTTTATTCCAGGGAGACTGCTTTTAGGTAT
AACTACATGTTGACAAGATTAAGTGCTGTGGATATGGCCACGTGTTAAAGGAATCTATACTCGCAATAGGAATAAGCTAATGCCCATTTT
CAGAAATAAATTAAATGCTGAAAGTGCCTGTCAGTAAACCTTATGACCAATGAGATATTCCTATACTTTTACACAGCAATAATTCTTAAT
AAGACTGGGTTTTTTCCTGCACATGTGAACACACACACACATACACACAGAGAGAGTAAATACATACACATAGTAAATCAAATCTGTTCA
CATGCCCACAAAAAACGCTTTTATAGCTTTCAAATATACCTAATCTTGTTTACATTAACATTTCTTAATTTGATCTTTCTAACTTGCAGA
ACGTTAAGAACACAAATCTGAACATTAAGTTTATCTTCAGTGAACACTATTGCATATGGTAATTATAATTTCCAGATAAAAAGTTGACTG
TCATTTGCCCCAAACTTATGAAACAGTATGTATGATTCAAAAAGTTTTGCTCAGTTAAAAACACCAATTTATTTGGCGCAAAAGACTGAA
GGATATTTGTTTGCTTGTTCATTTTATCCACTCATATCAAACGCACAAATTCATCTTTACATTTCTTCATTCCCCTTTCCCCTAATATTT
CCTATTATCATCTTAAGAATCATTTTGGAATGAATATTGACAGAATCATTTCTCCCCAAAAAGTCTGTTGAAGTACCACTGACACTTAGT
AAGCCTAGCCTTTAACCATCTTTGCAGTTAGTCCTAAAAATTACCAGATGCACATTCAGAAGCTCACAGGTTTTTTCCTGTAATTACTGT
ACTGCTAAAAGTGGAGTCATGGATAGAAATATACAATGAGACTATATGAATAGACATGAACCCTGGAAATTCTCCAACCCTGCCATCTCA
GAGCACAAATTCACCCAAACAAGCTACTGAGGCTATCAGTAAAATTATACTCATGGAGAGTCACACATCGGGTAAGGGCAATTTTAAAAG
TAGGACTGTGATTAAACATTCAGGCTTTAGACTTCCATGATGGACTCAGACCACAGGCCTCAAAAAAACATCCACTGTTTTCTCCTCCCA
ATGTTAGAAAGAAGAAAAGGGAGACGGAAATGTACCAGGATAAGGGGGTAAAATAACCAATTAAGTGTCAAAGGAAAGCTGCTGGGTTCC
TTAATCTCACTGAAGTCAAGTCTTCTGACTGGGCTTCTTACCATGTGTTGTCTGAAAAAACTAAAGTACCTTGAAAGGTTACACATTCAG
CAAACCATGAAGATAATAGCTATTCTTTATTAAACACTGTGTGCCAAGCAATAGACTAGGCAATTTTTAGATACGTTACCTGCAACCTGT
ACAACATTTCTACACTTTATGGATGGGAAACGGAGACATGGGAAGTGTGGCTGAGTTGTTCATGGATGTAGAAATAGTAAACGGCAGAGT
AGGAAAGTGAAACCGCCTATCTCTGACCTGGAGGTCTGCCTGTATCTTTCCCACTCCACCACACTGCACGTGGGTGTCCCGAAACCACCT
TCCCAGATTCCTGACTCTCAGTAATTTTATTATGGACAACATGCATGAGTAGTCATCATATTTTTCAAGTGAAATATCGGGACATGATAT
AACACATGACTTAACAATGGTACTGAATATTTGAAATCAGGCCTTTCCCGGAAAATCATGCATGAAGGATCATTATAAACAAACAATAGC
AACCAGTTGTCTCCCCGAACTTGTCACTTTTCTCATAAATGTCTGGCCTGGAGCTCCAAAATCATCCAAATACTTAGTAGCATTTTAGCC
TGAGTACACTTTCTCAGTTCCTCAACTCTTTGTATACCTTTCCACCAATATAGACATTCTAGAATCTGCTTCAGATGCATTTGAAATTTT
CACCCCCATGGAACTAGTGATTAATATCAGAGCCCACTCTTGCAGTTGGTAATGGGGTGGCAATCAAACGTTCAGATGATGATAAAGGAG
AGATAATGGATAATTCTTTTTCAGAGTTCTCACTTAACAGCTCTGTTGTGGAATGTTTTAAATAGTCTTATAAATAATTTGTTTATAGTA
TTGTTGTTAGTTTAATTGAATTTTATGTAAGAAGCTGTCCAACATCAGAGAAATGAAATTCCTCCCACTTTCTGTGTAGAACAAGGTCTC
TGACAGTATTGATTCATGGAAGTACTAATGGACTTAGAAAACATTAAGAGAATGTCATTTCTCATAGTGTTTCTGTTTCTGAAAATGAAT
CTCCTGAATTATTATCTTTCTCCCTGTTACTTGGCTGGGGAAAGAGATAGAAGCTGTATAAACAAATTCTCTTCCATGCTCAAAGCAAGT
GTTCCATGTGCACAACCTGCTGCAGACTGGGGCCCTTCTCAGTTAATTGGGTTTCACAAGCAATAATTTCTCCACAACAAAAACCACAAC
TTGAAGTGAGTTGAAAAGAGATCAATAGTGGAAACAGTCGCCTCAGTACTTTTTCTTTCTGGATTTCATCTCTAGAAATTTGAAGTGTTT
GAGACAGAGTCCACCCTTTGTGCAAGGCGAGAACCAATGAATGGACTCCTTGTGTGAATTATTGCATCTTCTTCCAAAGCAGGTTCATCA
AGACTTTCACAGAGATTCATTTTTGTTGAGAAGTAAGGGTTAATAGGAGGATAGAATTTGGATCCAAATCTAGTGATAAAAGTGTCCAAG
CAATCAAAAAGTAAGATATTTTAGGGACATACCAACATCTTCCCTTTCTGCTAATTTCATGCTCCAAAGATATGGCAAAAAAAAAAATCA
TAAAAAGTGCTTTTGCCCTACTTGTGTTCTAGTTTTCCCATGGCAGAATTTTGTAATTACATCCAGAATATAGTGTATATTTTGTTCCTC
AAACTTTATTACATTGGATGGATATTGTTGAACTGGGGCACTGGTGCCTATATTCAAGGCTCTTTCCTATCAACGTGTCTGTCCACGATT
TGTTGTGTTTAAAGCTTCATTTTGAAAAATCACTGTCCCCCTGTGGGGTAGTGACTGTATTGTTTTGTTCATGTCTATGTGGGACACATT
GCATCACATGGCAAACCAACTCTCTGTGGATGTGAGATAAGTACTTATAAAACCAGCTTGAAAACATCGTCTTATGTATTATGTCATCCT
GCATCATAATGCAATTATGTGTATCATAACATGCTCATTTAAAAAAAGAGAAACCAGCAAATTCATGTTTGTCCATAGAAGAATGTACTC
AGAACTTTGTGTTGTGAAACGATGAGAACAGACCACCTTTAAGATACCCACCTGCCACTTAAAATGACTTAGTTATAATTAGTAGTAGTC
TAGACGTTGTTCTTGGTGTGTGGGGGTCAATTCTAACGTCATGTTCTTTTGAATAAATCTCTCAGTCATATTTGAAAAAAAAATACATGG
GAATAAAGAAAAATATCATCTTTGGCCAAATCAAGCAGGCATCTTTTTTCTTTTCCTTGACGTTTAGCTCATTATACGTGGTGATTGGAT
CACGAGATCTGTCCGTGTGAAAATACAGAAACATCCTTTAGTTTACAAAACAGTTATTCTAGGCTTGAAGCCTCTGAACAGCAAATTGAA
TAGATGGGCTGCATCTGATTTGCTTTATGGATGTAATTTTACAAAACACTCTTGGGTCTCTGACCCCAGGGAGTTAAGAGTGCCCAGAGG
AGGTCCTACACATTAAAGGATAAAGCCCCCCAGTGATGCTGGCAAGCAAATGTGTTGAGTTCTTAAATCTTCATTTGGTTTTCTGTTCAG
GATTTTAATTGCAAATGAATTTATTTCTCCAGTTTATCTAAAGACCTAATTTCCCAATAGTTTCCTCTGCATTTATATACTCTGTAGTGT
TTAGGCAACCCTGTTATAAGTTTATTAATATTATGTAAGTGTTGTTCTTGTATTTATGTATAGTGTATGTATTGTAAATATACTCAGAGC
TTTTTTCCTTTTACTGTAAAATGGTGATTTTTTTGCCCTATGATAATGTAAAGGGAGACCCTCCTAATGAGATTCTCTCAGAGGATGATT
ATTCCAGTCTATTCTCAGAGATTTAAATGAACAAGTGTTATTGTTTTTAATGGTGTCTCAGACATATTCTGTTGGTGCATTGCTTTTCTG
TATTCAACTTTCCTATGAATTGAGCTGTGAACTGAAATAGAGTTTAAACCTTTAACTGTATGCATTTGTATAATTATCTGAATGAAGGCA

>22898_22898_4_DIS3-KLF12_DIS3_chr13_73345932_ENST00000377780_KLF12_chr13_74420510_ENST00000377669_length(amino acids)=866AA_BP=505
MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVCPQPHYLLPDTNVLLHQIVSAWRPGTWASVA
SSLRLPGSLETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRNKEKAIEEGIPAFTCEEYVKSLTANPELIDR
LACLSEEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLNRAVHEDIVAVELLPKS
QWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQA
STLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDP
PGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKSPNVHNYPDMEAVPLLLNNVKGEPPEDSLSVDHFQ
TQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSRLASSPTVITSVSSASSSSTVLTPGPLVASASGVGGQQFLHIIHP
VPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGRGHGKAQMDPRGLSPRQSKSDSDDDDLPNVTLDSVNET
GSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKP

--------------------------------------------------------------
>22898_22898_5_DIS3-KLF12_DIS3_chr13_73345933_ENST00000377767_KLF12_chr13_74420510_ENST00000377666_length(transcript)=2883nt_BP=1706nt
GGAATGGAAAGGGAAGAACCTCCGGGGTTAGGCGTATTCTAGATTGACGCCTTTTGCTGGAAGAGCGCTGCTGGGGTTAGGATTCTGCGC
GGCGAGGCAAGATGCTCAAGTCCAAGACGTTCTTAAAAAAGACCCGGGCGGGCGGCGTGATGAAGATCGTGCGCGAGCACTACCTGCGAG
ACGACATCGGCTGCGGTGCGCCCGGGTGCGCAGCGTGTGGAGGGGCGCACGAGGGGCCGGCCCTGGAGCCGCAGCCCCAGGACCCGGCGA
GCAGCGTCTGCCCGCAACCGCACTACTTGCTGCCCGACACTAATGTGTTACTGCACCAGATTGATGTTCTTGAGGACCCTGCCATCAGGA
ATGTAATTGTGCTACAAACAGTTCTTCAAGAAGTGAGAAATCGCAGTGCCCCCGTATATAAACGCATCCGAGATGTGACTAATAACCAAG
AGAAGCATTTCTATACTTTCACTAATGAGCACCATAGAGAAACCTATGTAGAACAAGAACAGGGAGAAAATGCTAATGACAGGAATGATA
GAGCGATTCGAGTAGCAGCAAAATGGTACAATGAACATTTGAAAAAAATGTCAGCAGACAACCAGCTGCAAGTTATCTTCATAACAAATG
ACAGGAGAAACAAAGAGAAAGCCATAGAAGAAGGAATACCAGCTTTCACTTGTGAAGAATATGTAAAGAGCCTAACTGCTAACCCCGAAC
TCATAGATCGTCTTGCTTGTTTGTCTGAAGAAGGGAATGAAATAGAAAGTGGAAAAATAATATTTTCAGAGCATCTTCCCTTAAGTAAGC
TACAGCAAGGCATAAAATCTGGTACATACCTTCAAGGAACATTTAGAGCTAGCAGGGAAAATTACTTGGAAGCTACAGTATGGATTCATG
GCGACAATGAAGAAAATAAAGAGATAATCTTACAGGGACTTAAACATTTAAACAGAGCTGTTCACGAAGATATTGTGGCTGTGGAGCTTC
TCCCCAAGAGTCAGTGGGTAGCACCATCTTCTGTGGTTTTACATGATGAAGGTCAAAATGAAGAAGATGTGGAGAAAGAAGAAGAGACAG
AACGAATGCTTAAGACTGCTGTAAGCGAGAAAATGTTGAAGCCTACAGGTAGAGTTGTAGGAATAATAAAAAGGAATTGGAGACCATATT
GTGGCATGCTTTCCAAGTCTGACATTAAGGAGTCAAGAAGACATCTCTTTACACCTGCTGATAAGAGAATCCCTCGAATTCGCATAGAAA
CCAGACAGGCTTCCACATTAGAAGGACGGAGAATTATTGTTGCTATTGATGGTTGGCCCAGAAATTCCAGATATCCAAATGGACACTTTG
TGAGAAATTTAGGTGATGTTGGAGAGAAAGAGACTGAAACAGAAGTTTTGTTACTTGAACACGATGTTCCCCATCAGCCTTTTTCACAGG
CTGTTCTTAGTTTTCTGCCAAAGATGCCCTGGAGCATTACTGAAAAGGACATGAAAAACCGAGAAGACCTGAGGCATCTGTGTATTTGTA
GTGTAGACCCACCAGGATGTACTGATATAGACGATGCTCTACATTGTCGAGAACTCGAAAATGGAAATTTGGAGGTTGGTGTTCATATTG
CTGATGTGAGCCATTTTATTAGGCCAGGAAATGCCTTGGATCAAGAATCAGCCAGAAGAGGAACAACTGTGTATCTTTGTGAAAAGTCTC
CAAACGTCCACAACTATCCCGATATGGAAGCCGTTCCCCTGTTGCTAAATAATGTGAAAGGGGAGCCCCCGGAGGACTCGTTATCTGTAG
ATCACTTCCAAACACAAACTGAGCCAGTGGACTTGTCAATAAACAAAGCCAGGACGTCCCCTACTGCCGTTTCATCCTCCCCAGTTTCCA
TGACAGCATCTGCCTCCTCACCTTCTTCAACTTCAACCTCTTCATCGTCTTCTAGTCGTCTAGCCTCATCCCCAACTGTTATCACATCAG
TATCTTCAGCGTCATCTTCGTCAACAGTATTAACTCCAGGGCCCCTTGTGGCCTCTGCATCTGGTGTTGGAGGCCAGCAGTTTTTGCACA
TTATCCATCCCGTACCGCCTTCAAGTCCCATGAATTTACAGTCTAACAAACTGAGTCATGTTCACCGCATCCCCGTGGTGGTACAGTCGG
TGCCTGTTGTCTACACAGCTGTAAGGTCACCTGGAAATGTGAACAACACTATTGTCGTGCCGCTTTTGGAGGATGGGAGAGGCCATGGCA
AAGCACAAATGGACCCCCGAGGCCTATCTCCCAGACAAAGTAAAAGTGACAGTGATGATGATGACCTGCCAAATGTGACCTTAGATAGCG
TTAATGAAACTGGATCTACGGCCCTTTCCATAGCCAGAGCAGTACAAGAGGTACATCCGTCCCCAGTATCAAGGGTCCGGGGCAATCGAA
TGAATAATCAAAAGTTTCCTTGTTCAATTTCACCATTTAGTATTGAGAGCACAAGACGCCAGAGACGGTCTGAATCCCCAGACTCCAGAA
AACGGCGTATCCACAGATGTGATTTTGAGGGATGCAACAAAGTGTACACAAAAAGTTCTCACCTGAAGGCTCACCGGAGGACACATACAG
GAGAGAAACCTTACAAGTGTACCTGGGAAGGCTGCACCTGGAAGTTCGCTCGTTCAGATGAACTGACGAGGCATTACCGCAAACATACGG
GAGTGAAGCCATTCAAGTGCGCGGACTGTGATCGCAGCTTTTCCCGGTCAGATCATTTGGCCCTGCACCGCCGGAGGCATATGTTGGTGT
GAGGAATGCTACCTGTCCAGCTGAGCGTAAGAGCTGGATCTCTTAGCGGCACCCAATTCAGCAGGGCTGAATCCCCTTCACAGTGTTAAC

>22898_22898_5_DIS3-KLF12_DIS3_chr13_73345933_ENST00000377767_KLF12_chr13_74420510_ENST00000377666_length(amino acids)=896AA_BP=535
MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVCPQPHYLLPDTNVLLHQIDVLEDPAIRNVIV
LQTVLQEVRNRSAPVYKRIRDVTNNQEKHFYTFTNEHHRETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRN
KEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNE
ENKEIILQGLKHLNRAVHEDIVAVELLPKSQWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGML
SKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLS
FLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKSPNVH
NYPDMEAVPLLLNNVKGEPPEDSLSVDHFQTQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSRLASSPTVITSVSSA
SSSSTVLTPGPLVASASGVGGQQFLHIIHPVPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGRGHGKAQM
DPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSISPFSIESTRRQRRSESPDSRKRRI

--------------------------------------------------------------
>22898_22898_6_DIS3-KLF12_DIS3_chr13_73345933_ENST00000377767_KLF12_chr13_74420510_ENST00000377669_length(transcript)=12193nt_BP=1706nt
GGAATGGAAAGGGAAGAACCTCCGGGGTTAGGCGTATTCTAGATTGACGCCTTTTGCTGGAAGAGCGCTGCTGGGGTTAGGATTCTGCGC
GGCGAGGCAAGATGCTCAAGTCCAAGACGTTCTTAAAAAAGACCCGGGCGGGCGGCGTGATGAAGATCGTGCGCGAGCACTACCTGCGAG
ACGACATCGGCTGCGGTGCGCCCGGGTGCGCAGCGTGTGGAGGGGCGCACGAGGGGCCGGCCCTGGAGCCGCAGCCCCAGGACCCGGCGA
GCAGCGTCTGCCCGCAACCGCACTACTTGCTGCCCGACACTAATGTGTTACTGCACCAGATTGATGTTCTTGAGGACCCTGCCATCAGGA
ATGTAATTGTGCTACAAACAGTTCTTCAAGAAGTGAGAAATCGCAGTGCCCCCGTATATAAACGCATCCGAGATGTGACTAATAACCAAG
AGAAGCATTTCTATACTTTCACTAATGAGCACCATAGAGAAACCTATGTAGAACAAGAACAGGGAGAAAATGCTAATGACAGGAATGATA
GAGCGATTCGAGTAGCAGCAAAATGGTACAATGAACATTTGAAAAAAATGTCAGCAGACAACCAGCTGCAAGTTATCTTCATAACAAATG
ACAGGAGAAACAAAGAGAAAGCCATAGAAGAAGGAATACCAGCTTTCACTTGTGAAGAATATGTAAAGAGCCTAACTGCTAACCCCGAAC
TCATAGATCGTCTTGCTTGTTTGTCTGAAGAAGGGAATGAAATAGAAAGTGGAAAAATAATATTTTCAGAGCATCTTCCCTTAAGTAAGC
TACAGCAAGGCATAAAATCTGGTACATACCTTCAAGGAACATTTAGAGCTAGCAGGGAAAATTACTTGGAAGCTACAGTATGGATTCATG
GCGACAATGAAGAAAATAAAGAGATAATCTTACAGGGACTTAAACATTTAAACAGAGCTGTTCACGAAGATATTGTGGCTGTGGAGCTTC
TCCCCAAGAGTCAGTGGGTAGCACCATCTTCTGTGGTTTTACATGATGAAGGTCAAAATGAAGAAGATGTGGAGAAAGAAGAAGAGACAG
AACGAATGCTTAAGACTGCTGTAAGCGAGAAAATGTTGAAGCCTACAGGTAGAGTTGTAGGAATAATAAAAAGGAATTGGAGACCATATT
GTGGCATGCTTTCCAAGTCTGACATTAAGGAGTCAAGAAGACATCTCTTTACACCTGCTGATAAGAGAATCCCTCGAATTCGCATAGAAA
CCAGACAGGCTTCCACATTAGAAGGACGGAGAATTATTGTTGCTATTGATGGTTGGCCCAGAAATTCCAGATATCCAAATGGACACTTTG
TGAGAAATTTAGGTGATGTTGGAGAGAAAGAGACTGAAACAGAAGTTTTGTTACTTGAACACGATGTTCCCCATCAGCCTTTTTCACAGG
CTGTTCTTAGTTTTCTGCCAAAGATGCCCTGGAGCATTACTGAAAAGGACATGAAAAACCGAGAAGACCTGAGGCATCTGTGTATTTGTA
GTGTAGACCCACCAGGATGTACTGATATAGACGATGCTCTACATTGTCGAGAACTCGAAAATGGAAATTTGGAGGTTGGTGTTCATATTG
CTGATGTGAGCCATTTTATTAGGCCAGGAAATGCCTTGGATCAAGAATCAGCCAGAAGAGGAACAACTGTGTATCTTTGTGAAAAGTCTC
CAAACGTCCACAACTATCCCGATATGGAAGCCGTTCCCCTGTTGCTAAATAATGTGAAAGGGGAGCCCCCGGAGGACTCGTTATCTGTAG
ATCACTTCCAAACACAAACTGAGCCAGTGGACTTGTCAATAAACAAAGCCAGGACGTCCCCTACTGCCGTTTCATCCTCCCCAGTTTCCA
TGACAGCATCTGCCTCCTCACCTTCTTCAACTTCAACCTCTTCATCGTCTTCTAGTCGTCTAGCCTCATCCCCAACTGTTATCACATCAG
TATCTTCAGCGTCATCTTCGTCAACAGTATTAACTCCAGGGCCCCTTGTGGCCTCTGCATCTGGTGTTGGAGGCCAGCAGTTTTTGCACA
TTATCCATCCCGTACCGCCTTCAAGTCCCATGAATTTACAGTCTAACAAACTGAGTCATGTTCACCGCATCCCCGTGGTGGTACAGTCGG
TGCCTGTTGTCTACACAGCTGTAAGGTCACCTGGAAATGTGAACAACACTATTGTCGTGCCGCTTTTGGAGGATGGGAGAGGCCATGGCA
AAGCACAAATGGACCCCCGAGGCCTATCTCCCAGACAAAGTAAAAGTGACAGTGATGATGATGACCTGCCAAATGTGACCTTAGATAGCG
TTAATGAAACTGGATCTACGGCCCTTTCCATAGCCAGAGCAGTACAAGAGGTACATCCGTCCCCAGTATCAAGGGTCCGGGGCAATCGAA
TGAATAATCAAAAGTTTCCTTGTTCAATTTCACCATTTAGTATTGAGAGCACAAGACGCCAGAGACGGTCTGAATCCCCAGACTCCAGAA
AACGGCGTATCCACAGATGTGATTTTGAGGGATGCAACAAAGTGTACACAAAAAGTTCTCACCTGAAGGCTCACCGGAGGACACATACAG
GAGAGAAACCTTACAAGTGTACCTGGGAAGGCTGCACCTGGAAGTTCGCTCGTTCAGATGAACTGACGAGGCATTACCGCAAACATACGG
GAGTGAAGCCATTCAAGTGCGCGGACTGTGATCGCAGCTTTTCCCGGTCAGATCATTTGGCCCTGCACCGCCGGAGGCATATGTTGGTGT
GAGGAATGCTACCTGTCCAGCTGAGCGTAAGAGCTGGATCTCTTAGCGGCACCCAATTCAGCAGGGCTGAATCCCCTTCACAGTGTTAAC
ACAAAAGGGCATCACCATCCCACGATGTCTGAAACCAGAGCAGGAAAAAGAAGGCACACTTCTTTTGGTCTGAAGGTAACCCCCATCATG
ACTAGACGAGAACCGTCTTTACCCGGGCCTGGGAGCTCAGTGACATAAATGCTGAAGAGACAGGCATTGTTTTCCGTGCTGTGTCCTCTG
CCATTTAAAGATGTTTGTAGCTTGTACATTTTCTGAGCTGTCAGACATTTTGTTATTGATACCTTAAAGGTCACCTACCACAAATTGATG
GCTAGAGCAAGACCTTTTAAATTTGGATGAATCTCCCATCATCCCATCCCTTAACCCCTTTTTACAGAAATTTTAGTTACAATCTGAGTA
AGCTAGAACACACATCCAATCTGTTACCAGCAAGCAGCATGAAAGTAGAAACGAAGAAGCAGATGGAGAGGTCCCATTACCTGCAAAGAA
AGGGCACTCAGGCAGCCCTTTGCAATCGCGATGGCAGCCACTAGATATCACTCTCAACTTGTCATTCTGCCATGCCCTGAAGAAAACCAA
CATTGAATCTTTCATTTGTTTGTCGTTGATTGTTTTTGTTTTGTTTCGATTCTGTTTTGTTCATCTGTTCGAGCAGAGGGGCAGTTGAAG
TCTCGTCCTGGTCTCTGCCCTGGCATGGACTGGCACAGAGGTGTTCTGTAGTTGAATAGGAAGAGCCTGTCTAAAAAACTACTGCCCCAC
TTCAAATTGCAGTGTTCTGTCACCTAGGCATCATCTCTTCCTGCCCCTAGTATTTGATTACAAGGAACCAGGGGAAAAAAACTTTCTTAG
ACACACTGGCACCAAGGTAAGAGGTGGGGCTGCCCAGGCAAAGTCAGTGAACATGAAAACTCAGACAAAGCAGAGATGGAAATAATGCGC
CTCTTGAGGAGAAAAGCAATAATGAATAAAAGGACTTTCCTACAATAACTTCACTGAGGACTCACGTTACCAATTTTCATACTTACTAAA
GGGATTGTAAAAAACACCCCAGCATTTTAGGTGTCTTGGTTCCATTTACAGCACTGAGGTAATCTTTCTGCTGTTTGTTGTCCTGCTTGG
TTGAGTACCACAATTAAAGATTATGCTCCCCTTTTCTTGTTTGAAAACAGTTATTTGGTGACTAGAAAGGCAAGGGAGGCATAGCCGGGA
ATTAACTCTTCGGTTAATGGGTCAGTTCTCCTTGGAACTGAATCAGTGGAAAGAGAATGCTTCCCATAGAAAGCCCGACATGGTGCTAGT
TTCCTCTCTTGGAGAGCCAAGGATAAGTGACTCTCCAATAGGTTCTTCTATACCGATTTCATTTTCTAAACTGTATCAGGACCCAGGTGT
CCTGCATTGGCATCTGCAGGGATATTGAACCCACTCATCCTGTGCAGAGGATGAGAGGAAGGTGTTAGTTCCATCAGCCCCATAAAATTA
TGAACCTTTTTGCAACTAGGAACATATACAGTAAACAAGCAATACATCACCAACGAGCATTCTTTCAGAAAAATTACCATATTTTTGTCC
CCACCACAAGCTGGGTTTTTTTCCAGCTTTCTGTGGCTGAGGGGCTGGTGAGATTTTTTGTTGTTATTGTTGTTGTTGCTAGAATTTTTT
ATAGCTTAGATATAAAAGGTCTCCAACAAAGACCTTTGCAATATATTTTAATTACAAACACTTGATTTTGGGAATTGCACATATTAACCT
CACAATATTACTAGCTCATTTTTAAATGTCTGGACATTCTGAAATAATTTCCGGTTACAGAATTACCCTTTTTAGGATCATCTTCTAATT
CAGATAATCTTATTCTGATGAAGCGAGAACTATGAACGTTGAAACAAGGACAATTTGTGTTGGATGGTATTCAAAAGGAATTTTTTAAAA
CATTAAGCAACAGTGTAATGATTTTCAGGTCAAATTATGGCTTCACAAATATGTGCTCTATATTGTCTGCCAGGTCTCAAAAATTCATCA
AGCAATTTCCCTCCAACAAGGGCTGCAGTTCTAGTGATAAATAGCATCTTTAGCTGCACAGTCTACTACTCATCAACCAGTGGGTTTTTT
TTAGCACCTGGAAAGTTTTTTTGTACTATATGCAACTCCTACTTCACATTGCCTGTGACCATTCAGAATAGAAAAAGGTCTGTTGATGCA
TGCCAGTGCTGGTTACTAGTCAGTGACAGAGAACACAGAGAGGGACAAACACAGCCATGAACCCCCTGGCACTAGTACCAGCACCTAGTT
GGCAAGTAGTGGGTGCATCTCTCAAGTGAAGTGTAGATTTGTATTTAGTCCTGCTTGCTCTCATAAAAAGAGCCAGTTCTTTTCTCTGCT
GAAAGATGTCTTGAGAGTATTACAGGTAGACTTGGTTTTTAGAATTCATAAAACTGACAGGCAGGGGAATCTTCCTGAGTGACAGCTTGG
TTTAAATTTAGCACAGAACTAGATGAGTTGCACTTTTCTAATAACATAGGATGGATTTGGGGAAGGGAACATTTTCCCTCATCCTCTGAA
AGTGGAAACCAGACTGAGATGGTAAGTTAACTGATAAAACCTGTCAGCATTCCATCATTTTCCCCTTTTGACGTATCAGTACTTCTAAGA
AGGGATCTAAGCACAATTAAGTGAATTGAGTCCCTGGTCTAGCCTCAGGAACTGAAACTTCTTTGGGGCTTGTCTTGAGACGTGGCAAAT
TCTCCTTGGTGAGTTTTCTAAAAGTATTTCCCCATGGAAAGGAGAAAGTGGTTTGGGACAGAAAGAAATGGAATGTCTTCAGTCATGGAA
GAGCCTCCATTTCATCTCATGTCCATTTCTAGCCTCTTTCAAAAAGCACAGTGCATCATGAGCAACAGAAAAGCAGTAGAATCCTAAAGG
ACATAACAGTTGTTCCGTAACTAGAAGCATTCTTTGATTTTAAATTTGAAGCTGTTCAGTTTGCAGCTGGGGATATGTGCATGGTTGGGA
ACTTATACACATAGAGCCATTAACTACTTAAGCAGCTGCAGTAGACCTGATTTTCTGTTTGCAGTATAGAGATTGATTTCAAGGGAGTTA
CATTATTTGAAAAGTTATGACTTTCAGCCTTTGAGGTTTTAAGAATCCCTTTTCATGGTCTGATCTTAAGTTGTTTGAAAAAAGATTCAC
GCTTCTGCATCCACCTCTGCCCTCATTCTGTCAATTGTGTGTGGACTCTGAGAAGCCTGCTTGATAACTTGTCTTAAGTTCTATTAAGGC
AGTTAGACTGAGATTTCTAATGACTTCACCATAAAGATTATACTTCTGCCTGGCGTCGTTTCTATAAAACACTATAGGACATTTGTTTTC
AAAAGCAGTTGAGTAACAGCAACATAAACCACATTTTTTAAAAAAATGAGCACTTTTCATTCACTTGAAAGCTTAAGTGGGAAAAAGGAA
GATGATTGTCAGGGGAAAAACTTACAAAATGCTACAGTGTTTACAAATGCCAGTTCCAGGTGATTAGAAAGGCCGTTTTCATTATGGTTC
AGATTTGGAATAGCTTATGCAAAGATTGTGTTCATTTTTATACAATTCTTTTTAACTTTAAATTGCCATCTGTGTTTTAAACATAATTCT
GCACTTTGGAATCAGTTCATTAGAATGATAACATTTATATGGATAAAGATGCAGTATTCCTTATTCTGTACTTGATTTATTATACTTACC
AAAGCTGCAACTGAATAAATCTGGTGAGGTGAGGCCTTCAAAATGTATTAATACGCCTTTGTTATGTTGTTATGACTGCTTAGAAATGTA
GCCATGATGTTGTTCTAAAGATGTCTTAACATTTATAGTGAGGATTGACAGAAATTAAGCAGTGTTAAGAATACCAGCATCCATGTTACA
GTCTGCGTATAAGGGACTGAATGTGAGGTAACTCTTATGAATCATAATAGGCCCAGAAAGCCTTAATATTCATAGTTCATAATCCAGTCT
CAGATTTTGCTCTTCAATGTTGCCTGTAAACTTAGCAGGTAAATGTATTCTAGTATAAAACATCATTGACCAAATCTCTTCCTTTAGTTT
TTCTGAGGTAGTGCATCCCATTAAAAAAGTCTCTTCAATTAGATTTGGCTTTAGTTTAGAAAGGGGTTTGGTAAGTCATGTCTTCCATAT
GACATTTCTACTCATCCCCACACTGCCTTCCACTTAACCTGTACAGACAGCCCCAACACATGCACATGTGTGTACACAACTGTATATGCA
GCAGCCAGTGGGCTAACAAATATCAGCAAAGAACTTTTTTAAAAAGAATTTGTAATAATCCGTGCTGTCTAGAAATGTGAGTTACTTACC
TTATTAGGAAACCGGCTTATAATACTATATATGACTCTGCCTGCATTTTATAGTTAAGAAATGTACATAAAAATTGCTATATTTTCACAG
TTTCATTATAATGTCTGTTTAGTAACCCATGTCCACTGATACTTTAAATATGCTAATTACTGAGCAATTGCAATAGAAATCCAGATTTTC
ATAAGAAAATGAAATAGAAGGATACTGCATCTTTAAAAAATAGAGTGAAGATATTTTACTGTATTCGTAACATATGTGATAGTGGAAAAA
GTATTTTCAAACTCACAAATTTTACAGAGGTTGTAAATAGTTTGATGAAGTATGTTGGGAAAGAGAGCTTCTAGTTTTCATCACAATAAA
AAGAAAAAACTTGTTCAGATATGCCTTGTATATCTTACACACAATGAGTGAAATTGCCATGGGAACTCTGTCCAACTTTGTCAGAGCATG
CTCTTCGTGTTCTGTTCAAAATAGAGTGGCCACTTGTCATGGTTTAGCCAGGATGGTTTAAAATATAATGAAGTCATTTTAAGTTGCAGA
CAACTGATTCCAAACTAGTAATGTCTTTTCCTGAAAAGGGCAAAACAGCTGCACAGGATTTTGCTTGTACTAAAGAGGAGCATCTTACAA
TTGTTCTCTTTTCTCAGTTATCTCCCTCCTCAACAGAGTGTGAACAACCATACAGGTGTTTATTCTTGTTTTATTCCAGGGAGACTGCTT
TTAGGTATAACTACATGTTGACAAGATTAAGTGCTGTGGATATGGCCACGTGTTAAAGGAATCTATACTCGCAATAGGAATAAGCTAATG
CCCATTTTCAGAAATAAATTAAATGCTGAAAGTGCCTGTCAGTAAACCTTATGACCAATGAGATATTCCTATACTTTTACACAGCAATAA
TTCTTAATAAGACTGGGTTTTTTCCTGCACATGTGAACACACACACACATACACACAGAGAGAGTAAATACATACACATAGTAAATCAAA
TCTGTTCACATGCCCACAAAAAACGCTTTTATAGCTTTCAAATATACCTAATCTTGTTTACATTAACATTTCTTAATTTGATCTTTCTAA
CTTGCAGAACGTTAAGAACACAAATCTGAACATTAAGTTTATCTTCAGTGAACACTATTGCATATGGTAATTATAATTTCCAGATAAAAA
GTTGACTGTCATTTGCCCCAAACTTATGAAACAGTATGTATGATTCAAAAAGTTTTGCTCAGTTAAAAACACCAATTTATTTGGCGCAAA
AGACTGAAGGATATTTGTTTGCTTGTTCATTTTATCCACTCATATCAAACGCACAAATTCATCTTTACATTTCTTCATTCCCCTTTCCCC
TAATATTTCCTATTATCATCTTAAGAATCATTTTGGAATGAATATTGACAGAATCATTTCTCCCCAAAAAGTCTGTTGAAGTACCACTGA
CACTTAGTAAGCCTAGCCTTTAACCATCTTTGCAGTTAGTCCTAAAAATTACCAGATGCACATTCAGAAGCTCACAGGTTTTTTCCTGTA
ATTACTGTACTGCTAAAAGTGGAGTCATGGATAGAAATATACAATGAGACTATATGAATAGACATGAACCCTGGAAATTCTCCAACCCTG
CCATCTCAGAGCACAAATTCACCCAAACAAGCTACTGAGGCTATCAGTAAAATTATACTCATGGAGAGTCACACATCGGGTAAGGGCAAT
TTTAAAAGTAGGACTGTGATTAAACATTCAGGCTTTAGACTTCCATGATGGACTCAGACCACAGGCCTCAAAAAAACATCCACTGTTTTC
TCCTCCCAATGTTAGAAAGAAGAAAAGGGAGACGGAAATGTACCAGGATAAGGGGGTAAAATAACCAATTAAGTGTCAAAGGAAAGCTGC
TGGGTTCCTTAATCTCACTGAAGTCAAGTCTTCTGACTGGGCTTCTTACCATGTGTTGTCTGAAAAAACTAAAGTACCTTGAAAGGTTAC
ACATTCAGCAAACCATGAAGATAATAGCTATTCTTTATTAAACACTGTGTGCCAAGCAATAGACTAGGCAATTTTTAGATACGTTACCTG
CAACCTGTACAACATTTCTACACTTTATGGATGGGAAACGGAGACATGGGAAGTGTGGCTGAGTTGTTCATGGATGTAGAAATAGTAAAC
GGCAGAGTAGGAAAGTGAAACCGCCTATCTCTGACCTGGAGGTCTGCCTGTATCTTTCCCACTCCACCACACTGCACGTGGGTGTCCCGA
AACCACCTTCCCAGATTCCTGACTCTCAGTAATTTTATTATGGACAACATGCATGAGTAGTCATCATATTTTTCAAGTGAAATATCGGGA
CATGATATAACACATGACTTAACAATGGTACTGAATATTTGAAATCAGGCCTTTCCCGGAAAATCATGCATGAAGGATCATTATAAACAA
ACAATAGCAACCAGTTGTCTCCCCGAACTTGTCACTTTTCTCATAAATGTCTGGCCTGGAGCTCCAAAATCATCCAAATACTTAGTAGCA
TTTTAGCCTGAGTACACTTTCTCAGTTCCTCAACTCTTTGTATACCTTTCCACCAATATAGACATTCTAGAATCTGCTTCAGATGCATTT
GAAATTTTCACCCCCATGGAACTAGTGATTAATATCAGAGCCCACTCTTGCAGTTGGTAATGGGGTGGCAATCAAACGTTCAGATGATGA
TAAAGGAGAGATAATGGATAATTCTTTTTCAGAGTTCTCACTTAACAGCTCTGTTGTGGAATGTTTTAAATAGTCTTATAAATAATTTGT
TTATAGTATTGTTGTTAGTTTAATTGAATTTTATGTAAGAAGCTGTCCAACATCAGAGAAATGAAATTCCTCCCACTTTCTGTGTAGAAC
AAGGTCTCTGACAGTATTGATTCATGGAAGTACTAATGGACTTAGAAAACATTAAGAGAATGTCATTTCTCATAGTGTTTCTGTTTCTGA
AAATGAATCTCCTGAATTATTATCTTTCTCCCTGTTACTTGGCTGGGGAAAGAGATAGAAGCTGTATAAACAAATTCTCTTCCATGCTCA
AAGCAAGTGTTCCATGTGCACAACCTGCTGCAGACTGGGGCCCTTCTCAGTTAATTGGGTTTCACAAGCAATAATTTCTCCACAACAAAA
ACCACAACTTGAAGTGAGTTGAAAAGAGATCAATAGTGGAAACAGTCGCCTCAGTACTTTTTCTTTCTGGATTTCATCTCTAGAAATTTG
AAGTGTTTGAGACAGAGTCCACCCTTTGTGCAAGGCGAGAACCAATGAATGGACTCCTTGTGTGAATTATTGCATCTTCTTCCAAAGCAG
GTTCATCAAGACTTTCACAGAGATTCATTTTTGTTGAGAAGTAAGGGTTAATAGGAGGATAGAATTTGGATCCAAATCTAGTGATAAAAG
TGTCCAAGCAATCAAAAAGTAAGATATTTTAGGGACATACCAACATCTTCCCTTTCTGCTAATTTCATGCTCCAAAGATATGGCAAAAAA
AAAAATCATAAAAAGTGCTTTTGCCCTACTTGTGTTCTAGTTTTCCCATGGCAGAATTTTGTAATTACATCCAGAATATAGTGTATATTT
TGTTCCTCAAACTTTATTACATTGGATGGATATTGTTGAACTGGGGCACTGGTGCCTATATTCAAGGCTCTTTCCTATCAACGTGTCTGT
CCACGATTTGTTGTGTTTAAAGCTTCATTTTGAAAAATCACTGTCCCCCTGTGGGGTAGTGACTGTATTGTTTTGTTCATGTCTATGTGG
GACACATTGCATCACATGGCAAACCAACTCTCTGTGGATGTGAGATAAGTACTTATAAAACCAGCTTGAAAACATCGTCTTATGTATTAT
GTCATCCTGCATCATAATGCAATTATGTGTATCATAACATGCTCATTTAAAAAAAGAGAAACCAGCAAATTCATGTTTGTCCATAGAAGA
ATGTACTCAGAACTTTGTGTTGTGAAACGATGAGAACAGACCACCTTTAAGATACCCACCTGCCACTTAAAATGACTTAGTTATAATTAG
TAGTAGTCTAGACGTTGTTCTTGGTGTGTGGGGGTCAATTCTAACGTCATGTTCTTTTGAATAAATCTCTCAGTCATATTTGAAAAAAAA
ATACATGGGAATAAAGAAAAATATCATCTTTGGCCAAATCAAGCAGGCATCTTTTTTCTTTTCCTTGACGTTTAGCTCATTATACGTGGT
GATTGGATCACGAGATCTGTCCGTGTGAAAATACAGAAACATCCTTTAGTTTACAAAACAGTTATTCTAGGCTTGAAGCCTCTGAACAGC
AAATTGAATAGATGGGCTGCATCTGATTTGCTTTATGGATGTAATTTTACAAAACACTCTTGGGTCTCTGACCCCAGGGAGTTAAGAGTG
CCCAGAGGAGGTCCTACACATTAAAGGATAAAGCCCCCCAGTGATGCTGGCAAGCAAATGTGTTGAGTTCTTAAATCTTCATTTGGTTTT
CTGTTCAGGATTTTAATTGCAAATGAATTTATTTCTCCAGTTTATCTAAAGACCTAATTTCCCAATAGTTTCCTCTGCATTTATATACTC
TGTAGTGTTTAGGCAACCCTGTTATAAGTTTATTAATATTATGTAAGTGTTGTTCTTGTATTTATGTATAGTGTATGTATTGTAAATATA
CTCAGAGCTTTTTTCCTTTTACTGTAAAATGGTGATTTTTTTGCCCTATGATAATGTAAAGGGAGACCCTCCTAATGAGATTCTCTCAGA
GGATGATTATTCCAGTCTATTCTCAGAGATTTAAATGAACAAGTGTTATTGTTTTTAATGGTGTCTCAGACATATTCTGTTGGTGCATTG
CTTTTCTGTATTCAACTTTCCTATGAATTGAGCTGTGAACTGAAATAGAGTTTAAACCTTTAACTGTATGCATTTGTATAATTATCTGAA

>22898_22898_6_DIS3-KLF12_DIS3_chr13_73345933_ENST00000377767_KLF12_chr13_74420510_ENST00000377669_length(amino acids)=896AA_BP=535
MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVCPQPHYLLPDTNVLLHQIDVLEDPAIRNVIV
LQTVLQEVRNRSAPVYKRIRDVTNNQEKHFYTFTNEHHRETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRN
KEKAIEEGIPAFTCEEYVKSLTANPELIDRLACLSEEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNE
ENKEIILQGLKHLNRAVHEDIVAVELLPKSQWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGML
SKSDIKESRRHLFTPADKRIPRIRIETRQASTLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLS
FLPKMPWSITEKDMKNREDLRHLCICSVDPPGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKSPNVH
NYPDMEAVPLLLNNVKGEPPEDSLSVDHFQTQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSRLASSPTVITSVSSA
SSSSTVLTPGPLVASASGVGGQQFLHIIHPVPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGRGHGKAQM
DPRGLSPRQSKSDSDDDDLPNVTLDSVNETGSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSISPFSIESTRRQRRSESPDSRKRRI

--------------------------------------------------------------
>22898_22898_7_DIS3-KLF12_DIS3_chr13_73345933_ENST00000377780_KLF12_chr13_74420510_ENST00000377666_length(transcript)=2785nt_BP=1608nt
AAGGGAAGAACCTCCGGGGTTAGGCGTATTCTAGATTGACGCCTTTTGCTGGAAGAGCGCTGCTGGGGTTAGGATTCTGCGCGGCGAGGC
AAGATGCTCAAGTCCAAGACGTTCTTAAAAAAGACCCGGGCGGGCGGCGTGATGAAGATCGTGCGCGAGCACTACCTGCGAGACGACATC
GGCTGCGGTGCGCCCGGGTGCGCAGCGTGTGGAGGGGCGCACGAGGGGCCGGCCCTGGAGCCGCAGCCCCAGGACCCGGCGAGCAGCGTC
TGCCCGCAACCGCACTACTTGCTGCCCGACACTAATGTGTTACTGCACCAGATTGTAAGTGCCTGGAGGCCGGGGACCTGGGCTTCTGTG
GCCTCCAGCCTGCGACTCCCAGGCAGCTTAGAAACCTATGTAGAACAAGAACAGGGAGAAAATGCTAATGACAGGAATGATAGAGCGATT
CGAGTAGCAGCAAAATGGTACAATGAACATTTGAAAAAAATGTCAGCAGACAACCAGCTGCAAGTTATCTTCATAACAAATGACAGGAGA
AACAAAGAGAAAGCCATAGAAGAAGGAATACCAGCTTTCACTTGTGAAGAATATGTAAAGAGCCTAACTGCTAACCCCGAACTCATAGAT
CGTCTTGCTTGTTTGTCTGAAGAAGGGAATGAAATAGAAAGTGGAAAAATAATATTTTCAGAGCATCTTCCCTTAAGTAAGCTACAGCAA
GGCATAAAATCTGGTACATACCTTCAAGGAACATTTAGAGCTAGCAGGGAAAATTACTTGGAAGCTACAGTATGGATTCATGGCGACAAT
GAAGAAAATAAAGAGATAATCTTACAGGGACTTAAACATTTAAACAGAGCTGTTCACGAAGATATTGTGGCTGTGGAGCTTCTCCCCAAG
AGTCAGTGGGTAGCACCATCTTCTGTGGTTTTACATGATGAAGGTCAAAATGAAGAAGATGTGGAGAAAGAAGAAGAGACAGAACGAATG
CTTAAGACTGCTGTAAGCGAGAAAATGTTGAAGCCTACAGGTAGAGTTGTAGGAATAATAAAAAGGAATTGGAGACCATATTGTGGCATG
CTTTCCAAGTCTGACATTAAGGAGTCAAGAAGACATCTCTTTACACCTGCTGATAAGAGAATCCCTCGAATTCGCATAGAAACCAGACAG
GCTTCCACATTAGAAGGACGGAGAATTATTGTTGCTATTGATGGTTGGCCCAGAAATTCCAGATATCCAAATGGACACTTTGTGAGAAAT
TTAGGTGATGTTGGAGAGAAAGAGACTGAAACAGAAGTTTTGTTACTTGAACACGATGTTCCCCATCAGCCTTTTTCACAGGCTGTTCTT
AGTTTTCTGCCAAAGATGCCCTGGAGCATTACTGAAAAGGACATGAAAAACCGAGAAGACCTGAGGCATCTGTGTATTTGTAGTGTAGAC
CCACCAGGATGTACTGATATAGACGATGCTCTACATTGTCGAGAACTCGAAAATGGAAATTTGGAGGTTGGTGTTCATATTGCTGATGTG
AGCCATTTTATTAGGCCAGGAAATGCCTTGGATCAAGAATCAGCCAGAAGAGGAACAACTGTGTATCTTTGTGAAAAGTCTCCAAACGTC
CACAACTATCCCGATATGGAAGCCGTTCCCCTGTTGCTAAATAATGTGAAAGGGGAGCCCCCGGAGGACTCGTTATCTGTAGATCACTTC
CAAACACAAACTGAGCCAGTGGACTTGTCAATAAACAAAGCCAGGACGTCCCCTACTGCCGTTTCATCCTCCCCAGTTTCCATGACAGCA
TCTGCCTCCTCACCTTCTTCAACTTCAACCTCTTCATCGTCTTCTAGTCGTCTAGCCTCATCCCCAACTGTTATCACATCAGTATCTTCA
GCGTCATCTTCGTCAACAGTATTAACTCCAGGGCCCCTTGTGGCCTCTGCATCTGGTGTTGGAGGCCAGCAGTTTTTGCACATTATCCAT
CCCGTACCGCCTTCAAGTCCCATGAATTTACAGTCTAACAAACTGAGTCATGTTCACCGCATCCCCGTGGTGGTACAGTCGGTGCCTGTT
GTCTACACAGCTGTAAGGTCACCTGGAAATGTGAACAACACTATTGTCGTGCCGCTTTTGGAGGATGGGAGAGGCCATGGCAAAGCACAA
ATGGACCCCCGAGGCCTATCTCCCAGACAAAGTAAAAGTGACAGTGATGATGATGACCTGCCAAATGTGACCTTAGATAGCGTTAATGAA
ACTGGATCTACGGCCCTTTCCATAGCCAGAGCAGTACAAGAGGTACATCCGTCCCCAGTATCAAGGGTCCGGGGCAATCGAATGAATAAT
CAAAAGTTTCCTTGTTCAATTTCACCATTTAGTATTGAGAGCACAAGACGCCAGAGACGGTCTGAATCCCCAGACTCCAGAAAACGGCGT
ATCCACAGATGTGATTTTGAGGGATGCAACAAAGTGTACACAAAAAGTTCTCACCTGAAGGCTCACCGGAGGACACATACAGGAGAGAAA
CCTTACAAGTGTACCTGGGAAGGCTGCACCTGGAAGTTCGCTCGTTCAGATGAACTGACGAGGCATTACCGCAAACATACGGGAGTGAAG
CCATTCAAGTGCGCGGACTGTGATCGCAGCTTTTCCCGGTCAGATCATTTGGCCCTGCACCGCCGGAGGCATATGTTGGTGTGAGGAATG

>22898_22898_7_DIS3-KLF12_DIS3_chr13_73345933_ENST00000377780_KLF12_chr13_74420510_ENST00000377666_length(amino acids)=866AA_BP=505
MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVCPQPHYLLPDTNVLLHQIVSAWRPGTWASVA
SSLRLPGSLETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRNKEKAIEEGIPAFTCEEYVKSLTANPELIDR
LACLSEEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLNRAVHEDIVAVELLPKS
QWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQA
STLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDP
PGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKSPNVHNYPDMEAVPLLLNNVKGEPPEDSLSVDHFQ
TQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSRLASSPTVITSVSSASSSSTVLTPGPLVASASGVGGQQFLHIIHP
VPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGRGHGKAQMDPRGLSPRQSKSDSDDDDLPNVTLDSVNET
GSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKP

--------------------------------------------------------------
>22898_22898_8_DIS3-KLF12_DIS3_chr13_73345933_ENST00000377780_KLF12_chr13_74420510_ENST00000377669_length(transcript)=12095nt_BP=1608nt
AAGGGAAGAACCTCCGGGGTTAGGCGTATTCTAGATTGACGCCTTTTGCTGGAAGAGCGCTGCTGGGGTTAGGATTCTGCGCGGCGAGGC
AAGATGCTCAAGTCCAAGACGTTCTTAAAAAAGACCCGGGCGGGCGGCGTGATGAAGATCGTGCGCGAGCACTACCTGCGAGACGACATC
GGCTGCGGTGCGCCCGGGTGCGCAGCGTGTGGAGGGGCGCACGAGGGGCCGGCCCTGGAGCCGCAGCCCCAGGACCCGGCGAGCAGCGTC
TGCCCGCAACCGCACTACTTGCTGCCCGACACTAATGTGTTACTGCACCAGATTGTAAGTGCCTGGAGGCCGGGGACCTGGGCTTCTGTG
GCCTCCAGCCTGCGACTCCCAGGCAGCTTAGAAACCTATGTAGAACAAGAACAGGGAGAAAATGCTAATGACAGGAATGATAGAGCGATT
CGAGTAGCAGCAAAATGGTACAATGAACATTTGAAAAAAATGTCAGCAGACAACCAGCTGCAAGTTATCTTCATAACAAATGACAGGAGA
AACAAAGAGAAAGCCATAGAAGAAGGAATACCAGCTTTCACTTGTGAAGAATATGTAAAGAGCCTAACTGCTAACCCCGAACTCATAGAT
CGTCTTGCTTGTTTGTCTGAAGAAGGGAATGAAATAGAAAGTGGAAAAATAATATTTTCAGAGCATCTTCCCTTAAGTAAGCTACAGCAA
GGCATAAAATCTGGTACATACCTTCAAGGAACATTTAGAGCTAGCAGGGAAAATTACTTGGAAGCTACAGTATGGATTCATGGCGACAAT
GAAGAAAATAAAGAGATAATCTTACAGGGACTTAAACATTTAAACAGAGCTGTTCACGAAGATATTGTGGCTGTGGAGCTTCTCCCCAAG
AGTCAGTGGGTAGCACCATCTTCTGTGGTTTTACATGATGAAGGTCAAAATGAAGAAGATGTGGAGAAAGAAGAAGAGACAGAACGAATG
CTTAAGACTGCTGTAAGCGAGAAAATGTTGAAGCCTACAGGTAGAGTTGTAGGAATAATAAAAAGGAATTGGAGACCATATTGTGGCATG
CTTTCCAAGTCTGACATTAAGGAGTCAAGAAGACATCTCTTTACACCTGCTGATAAGAGAATCCCTCGAATTCGCATAGAAACCAGACAG
GCTTCCACATTAGAAGGACGGAGAATTATTGTTGCTATTGATGGTTGGCCCAGAAATTCCAGATATCCAAATGGACACTTTGTGAGAAAT
TTAGGTGATGTTGGAGAGAAAGAGACTGAAACAGAAGTTTTGTTACTTGAACACGATGTTCCCCATCAGCCTTTTTCACAGGCTGTTCTT
AGTTTTCTGCCAAAGATGCCCTGGAGCATTACTGAAAAGGACATGAAAAACCGAGAAGACCTGAGGCATCTGTGTATTTGTAGTGTAGAC
CCACCAGGATGTACTGATATAGACGATGCTCTACATTGTCGAGAACTCGAAAATGGAAATTTGGAGGTTGGTGTTCATATTGCTGATGTG
AGCCATTTTATTAGGCCAGGAAATGCCTTGGATCAAGAATCAGCCAGAAGAGGAACAACTGTGTATCTTTGTGAAAAGTCTCCAAACGTC
CACAACTATCCCGATATGGAAGCCGTTCCCCTGTTGCTAAATAATGTGAAAGGGGAGCCCCCGGAGGACTCGTTATCTGTAGATCACTTC
CAAACACAAACTGAGCCAGTGGACTTGTCAATAAACAAAGCCAGGACGTCCCCTACTGCCGTTTCATCCTCCCCAGTTTCCATGACAGCA
TCTGCCTCCTCACCTTCTTCAACTTCAACCTCTTCATCGTCTTCTAGTCGTCTAGCCTCATCCCCAACTGTTATCACATCAGTATCTTCA
GCGTCATCTTCGTCAACAGTATTAACTCCAGGGCCCCTTGTGGCCTCTGCATCTGGTGTTGGAGGCCAGCAGTTTTTGCACATTATCCAT
CCCGTACCGCCTTCAAGTCCCATGAATTTACAGTCTAACAAACTGAGTCATGTTCACCGCATCCCCGTGGTGGTACAGTCGGTGCCTGTT
GTCTACACAGCTGTAAGGTCACCTGGAAATGTGAACAACACTATTGTCGTGCCGCTTTTGGAGGATGGGAGAGGCCATGGCAAAGCACAA
ATGGACCCCCGAGGCCTATCTCCCAGACAAAGTAAAAGTGACAGTGATGATGATGACCTGCCAAATGTGACCTTAGATAGCGTTAATGAA
ACTGGATCTACGGCCCTTTCCATAGCCAGAGCAGTACAAGAGGTACATCCGTCCCCAGTATCAAGGGTCCGGGGCAATCGAATGAATAAT
CAAAAGTTTCCTTGTTCAATTTCACCATTTAGTATTGAGAGCACAAGACGCCAGAGACGGTCTGAATCCCCAGACTCCAGAAAACGGCGT
ATCCACAGATGTGATTTTGAGGGATGCAACAAAGTGTACACAAAAAGTTCTCACCTGAAGGCTCACCGGAGGACACATACAGGAGAGAAA
CCTTACAAGTGTACCTGGGAAGGCTGCACCTGGAAGTTCGCTCGTTCAGATGAACTGACGAGGCATTACCGCAAACATACGGGAGTGAAG
CCATTCAAGTGCGCGGACTGTGATCGCAGCTTTTCCCGGTCAGATCATTTGGCCCTGCACCGCCGGAGGCATATGTTGGTGTGAGGAATG
CTACCTGTCCAGCTGAGCGTAAGAGCTGGATCTCTTAGCGGCACCCAATTCAGCAGGGCTGAATCCCCTTCACAGTGTTAACACAAAAGG
GCATCACCATCCCACGATGTCTGAAACCAGAGCAGGAAAAAGAAGGCACACTTCTTTTGGTCTGAAGGTAACCCCCATCATGACTAGACG
AGAACCGTCTTTACCCGGGCCTGGGAGCTCAGTGACATAAATGCTGAAGAGACAGGCATTGTTTTCCGTGCTGTGTCCTCTGCCATTTAA
AGATGTTTGTAGCTTGTACATTTTCTGAGCTGTCAGACATTTTGTTATTGATACCTTAAAGGTCACCTACCACAAATTGATGGCTAGAGC
AAGACCTTTTAAATTTGGATGAATCTCCCATCATCCCATCCCTTAACCCCTTTTTACAGAAATTTTAGTTACAATCTGAGTAAGCTAGAA
CACACATCCAATCTGTTACCAGCAAGCAGCATGAAAGTAGAAACGAAGAAGCAGATGGAGAGGTCCCATTACCTGCAAAGAAAGGGCACT
CAGGCAGCCCTTTGCAATCGCGATGGCAGCCACTAGATATCACTCTCAACTTGTCATTCTGCCATGCCCTGAAGAAAACCAACATTGAAT
CTTTCATTTGTTTGTCGTTGATTGTTTTTGTTTTGTTTCGATTCTGTTTTGTTCATCTGTTCGAGCAGAGGGGCAGTTGAAGTCTCGTCC
TGGTCTCTGCCCTGGCATGGACTGGCACAGAGGTGTTCTGTAGTTGAATAGGAAGAGCCTGTCTAAAAAACTACTGCCCCACTTCAAATT
GCAGTGTTCTGTCACCTAGGCATCATCTCTTCCTGCCCCTAGTATTTGATTACAAGGAACCAGGGGAAAAAAACTTTCTTAGACACACTG
GCACCAAGGTAAGAGGTGGGGCTGCCCAGGCAAAGTCAGTGAACATGAAAACTCAGACAAAGCAGAGATGGAAATAATGCGCCTCTTGAG
GAGAAAAGCAATAATGAATAAAAGGACTTTCCTACAATAACTTCACTGAGGACTCACGTTACCAATTTTCATACTTACTAAAGGGATTGT
AAAAAACACCCCAGCATTTTAGGTGTCTTGGTTCCATTTACAGCACTGAGGTAATCTTTCTGCTGTTTGTTGTCCTGCTTGGTTGAGTAC
CACAATTAAAGATTATGCTCCCCTTTTCTTGTTTGAAAACAGTTATTTGGTGACTAGAAAGGCAAGGGAGGCATAGCCGGGAATTAACTC
TTCGGTTAATGGGTCAGTTCTCCTTGGAACTGAATCAGTGGAAAGAGAATGCTTCCCATAGAAAGCCCGACATGGTGCTAGTTTCCTCTC
TTGGAGAGCCAAGGATAAGTGACTCTCCAATAGGTTCTTCTATACCGATTTCATTTTCTAAACTGTATCAGGACCCAGGTGTCCTGCATT
GGCATCTGCAGGGATATTGAACCCACTCATCCTGTGCAGAGGATGAGAGGAAGGTGTTAGTTCCATCAGCCCCATAAAATTATGAACCTT
TTTGCAACTAGGAACATATACAGTAAACAAGCAATACATCACCAACGAGCATTCTTTCAGAAAAATTACCATATTTTTGTCCCCACCACA
AGCTGGGTTTTTTTCCAGCTTTCTGTGGCTGAGGGGCTGGTGAGATTTTTTGTTGTTATTGTTGTTGTTGCTAGAATTTTTTATAGCTTA
GATATAAAAGGTCTCCAACAAAGACCTTTGCAATATATTTTAATTACAAACACTTGATTTTGGGAATTGCACATATTAACCTCACAATAT
TACTAGCTCATTTTTAAATGTCTGGACATTCTGAAATAATTTCCGGTTACAGAATTACCCTTTTTAGGATCATCTTCTAATTCAGATAAT
CTTATTCTGATGAAGCGAGAACTATGAACGTTGAAACAAGGACAATTTGTGTTGGATGGTATTCAAAAGGAATTTTTTAAAACATTAAGC
AACAGTGTAATGATTTTCAGGTCAAATTATGGCTTCACAAATATGTGCTCTATATTGTCTGCCAGGTCTCAAAAATTCATCAAGCAATTT
CCCTCCAACAAGGGCTGCAGTTCTAGTGATAAATAGCATCTTTAGCTGCACAGTCTACTACTCATCAACCAGTGGGTTTTTTTTAGCACC
TGGAAAGTTTTTTTGTACTATATGCAACTCCTACTTCACATTGCCTGTGACCATTCAGAATAGAAAAAGGTCTGTTGATGCATGCCAGTG
CTGGTTACTAGTCAGTGACAGAGAACACAGAGAGGGACAAACACAGCCATGAACCCCCTGGCACTAGTACCAGCACCTAGTTGGCAAGTA
GTGGGTGCATCTCTCAAGTGAAGTGTAGATTTGTATTTAGTCCTGCTTGCTCTCATAAAAAGAGCCAGTTCTTTTCTCTGCTGAAAGATG
TCTTGAGAGTATTACAGGTAGACTTGGTTTTTAGAATTCATAAAACTGACAGGCAGGGGAATCTTCCTGAGTGACAGCTTGGTTTAAATT
TAGCACAGAACTAGATGAGTTGCACTTTTCTAATAACATAGGATGGATTTGGGGAAGGGAACATTTTCCCTCATCCTCTGAAAGTGGAAA
CCAGACTGAGATGGTAAGTTAACTGATAAAACCTGTCAGCATTCCATCATTTTCCCCTTTTGACGTATCAGTACTTCTAAGAAGGGATCT
AAGCACAATTAAGTGAATTGAGTCCCTGGTCTAGCCTCAGGAACTGAAACTTCTTTGGGGCTTGTCTTGAGACGTGGCAAATTCTCCTTG
GTGAGTTTTCTAAAAGTATTTCCCCATGGAAAGGAGAAAGTGGTTTGGGACAGAAAGAAATGGAATGTCTTCAGTCATGGAAGAGCCTCC
ATTTCATCTCATGTCCATTTCTAGCCTCTTTCAAAAAGCACAGTGCATCATGAGCAACAGAAAAGCAGTAGAATCCTAAAGGACATAACA
GTTGTTCCGTAACTAGAAGCATTCTTTGATTTTAAATTTGAAGCTGTTCAGTTTGCAGCTGGGGATATGTGCATGGTTGGGAACTTATAC
ACATAGAGCCATTAACTACTTAAGCAGCTGCAGTAGACCTGATTTTCTGTTTGCAGTATAGAGATTGATTTCAAGGGAGTTACATTATTT
GAAAAGTTATGACTTTCAGCCTTTGAGGTTTTAAGAATCCCTTTTCATGGTCTGATCTTAAGTTGTTTGAAAAAAGATTCACGCTTCTGC
ATCCACCTCTGCCCTCATTCTGTCAATTGTGTGTGGACTCTGAGAAGCCTGCTTGATAACTTGTCTTAAGTTCTATTAAGGCAGTTAGAC
TGAGATTTCTAATGACTTCACCATAAAGATTATACTTCTGCCTGGCGTCGTTTCTATAAAACACTATAGGACATTTGTTTTCAAAAGCAG
TTGAGTAACAGCAACATAAACCACATTTTTTAAAAAAATGAGCACTTTTCATTCACTTGAAAGCTTAAGTGGGAAAAAGGAAGATGATTG
TCAGGGGAAAAACTTACAAAATGCTACAGTGTTTACAAATGCCAGTTCCAGGTGATTAGAAAGGCCGTTTTCATTATGGTTCAGATTTGG
AATAGCTTATGCAAAGATTGTGTTCATTTTTATACAATTCTTTTTAACTTTAAATTGCCATCTGTGTTTTAAACATAATTCTGCACTTTG
GAATCAGTTCATTAGAATGATAACATTTATATGGATAAAGATGCAGTATTCCTTATTCTGTACTTGATTTATTATACTTACCAAAGCTGC
AACTGAATAAATCTGGTGAGGTGAGGCCTTCAAAATGTATTAATACGCCTTTGTTATGTTGTTATGACTGCTTAGAAATGTAGCCATGAT
GTTGTTCTAAAGATGTCTTAACATTTATAGTGAGGATTGACAGAAATTAAGCAGTGTTAAGAATACCAGCATCCATGTTACAGTCTGCGT
ATAAGGGACTGAATGTGAGGTAACTCTTATGAATCATAATAGGCCCAGAAAGCCTTAATATTCATAGTTCATAATCCAGTCTCAGATTTT
GCTCTTCAATGTTGCCTGTAAACTTAGCAGGTAAATGTATTCTAGTATAAAACATCATTGACCAAATCTCTTCCTTTAGTTTTTCTGAGG
TAGTGCATCCCATTAAAAAAGTCTCTTCAATTAGATTTGGCTTTAGTTTAGAAAGGGGTTTGGTAAGTCATGTCTTCCATATGACATTTC
TACTCATCCCCACACTGCCTTCCACTTAACCTGTACAGACAGCCCCAACACATGCACATGTGTGTACACAACTGTATATGCAGCAGCCAG
TGGGCTAACAAATATCAGCAAAGAACTTTTTTAAAAAGAATTTGTAATAATCCGTGCTGTCTAGAAATGTGAGTTACTTACCTTATTAGG
AAACCGGCTTATAATACTATATATGACTCTGCCTGCATTTTATAGTTAAGAAATGTACATAAAAATTGCTATATTTTCACAGTTTCATTA
TAATGTCTGTTTAGTAACCCATGTCCACTGATACTTTAAATATGCTAATTACTGAGCAATTGCAATAGAAATCCAGATTTTCATAAGAAA
ATGAAATAGAAGGATACTGCATCTTTAAAAAATAGAGTGAAGATATTTTACTGTATTCGTAACATATGTGATAGTGGAAAAAGTATTTTC
AAACTCACAAATTTTACAGAGGTTGTAAATAGTTTGATGAAGTATGTTGGGAAAGAGAGCTTCTAGTTTTCATCACAATAAAAAGAAAAA
ACTTGTTCAGATATGCCTTGTATATCTTACACACAATGAGTGAAATTGCCATGGGAACTCTGTCCAACTTTGTCAGAGCATGCTCTTCGT
GTTCTGTTCAAAATAGAGTGGCCACTTGTCATGGTTTAGCCAGGATGGTTTAAAATATAATGAAGTCATTTTAAGTTGCAGACAACTGAT
TCCAAACTAGTAATGTCTTTTCCTGAAAAGGGCAAAACAGCTGCACAGGATTTTGCTTGTACTAAAGAGGAGCATCTTACAATTGTTCTC
TTTTCTCAGTTATCTCCCTCCTCAACAGAGTGTGAACAACCATACAGGTGTTTATTCTTGTTTTATTCCAGGGAGACTGCTTTTAGGTAT
AACTACATGTTGACAAGATTAAGTGCTGTGGATATGGCCACGTGTTAAAGGAATCTATACTCGCAATAGGAATAAGCTAATGCCCATTTT
CAGAAATAAATTAAATGCTGAAAGTGCCTGTCAGTAAACCTTATGACCAATGAGATATTCCTATACTTTTACACAGCAATAATTCTTAAT
AAGACTGGGTTTTTTCCTGCACATGTGAACACACACACACATACACACAGAGAGAGTAAATACATACACATAGTAAATCAAATCTGTTCA
CATGCCCACAAAAAACGCTTTTATAGCTTTCAAATATACCTAATCTTGTTTACATTAACATTTCTTAATTTGATCTTTCTAACTTGCAGA
ACGTTAAGAACACAAATCTGAACATTAAGTTTATCTTCAGTGAACACTATTGCATATGGTAATTATAATTTCCAGATAAAAAGTTGACTG
TCATTTGCCCCAAACTTATGAAACAGTATGTATGATTCAAAAAGTTTTGCTCAGTTAAAAACACCAATTTATTTGGCGCAAAAGACTGAA
GGATATTTGTTTGCTTGTTCATTTTATCCACTCATATCAAACGCACAAATTCATCTTTACATTTCTTCATTCCCCTTTCCCCTAATATTT
CCTATTATCATCTTAAGAATCATTTTGGAATGAATATTGACAGAATCATTTCTCCCCAAAAAGTCTGTTGAAGTACCACTGACACTTAGT
AAGCCTAGCCTTTAACCATCTTTGCAGTTAGTCCTAAAAATTACCAGATGCACATTCAGAAGCTCACAGGTTTTTTCCTGTAATTACTGT
ACTGCTAAAAGTGGAGTCATGGATAGAAATATACAATGAGACTATATGAATAGACATGAACCCTGGAAATTCTCCAACCCTGCCATCTCA
GAGCACAAATTCACCCAAACAAGCTACTGAGGCTATCAGTAAAATTATACTCATGGAGAGTCACACATCGGGTAAGGGCAATTTTAAAAG
TAGGACTGTGATTAAACATTCAGGCTTTAGACTTCCATGATGGACTCAGACCACAGGCCTCAAAAAAACATCCACTGTTTTCTCCTCCCA
ATGTTAGAAAGAAGAAAAGGGAGACGGAAATGTACCAGGATAAGGGGGTAAAATAACCAATTAAGTGTCAAAGGAAAGCTGCTGGGTTCC
TTAATCTCACTGAAGTCAAGTCTTCTGACTGGGCTTCTTACCATGTGTTGTCTGAAAAAACTAAAGTACCTTGAAAGGTTACACATTCAG
CAAACCATGAAGATAATAGCTATTCTTTATTAAACACTGTGTGCCAAGCAATAGACTAGGCAATTTTTAGATACGTTACCTGCAACCTGT
ACAACATTTCTACACTTTATGGATGGGAAACGGAGACATGGGAAGTGTGGCTGAGTTGTTCATGGATGTAGAAATAGTAAACGGCAGAGT
AGGAAAGTGAAACCGCCTATCTCTGACCTGGAGGTCTGCCTGTATCTTTCCCACTCCACCACACTGCACGTGGGTGTCCCGAAACCACCT
TCCCAGATTCCTGACTCTCAGTAATTTTATTATGGACAACATGCATGAGTAGTCATCATATTTTTCAAGTGAAATATCGGGACATGATAT
AACACATGACTTAACAATGGTACTGAATATTTGAAATCAGGCCTTTCCCGGAAAATCATGCATGAAGGATCATTATAAACAAACAATAGC
AACCAGTTGTCTCCCCGAACTTGTCACTTTTCTCATAAATGTCTGGCCTGGAGCTCCAAAATCATCCAAATACTTAGTAGCATTTTAGCC
TGAGTACACTTTCTCAGTTCCTCAACTCTTTGTATACCTTTCCACCAATATAGACATTCTAGAATCTGCTTCAGATGCATTTGAAATTTT
CACCCCCATGGAACTAGTGATTAATATCAGAGCCCACTCTTGCAGTTGGTAATGGGGTGGCAATCAAACGTTCAGATGATGATAAAGGAG
AGATAATGGATAATTCTTTTTCAGAGTTCTCACTTAACAGCTCTGTTGTGGAATGTTTTAAATAGTCTTATAAATAATTTGTTTATAGTA
TTGTTGTTAGTTTAATTGAATTTTATGTAAGAAGCTGTCCAACATCAGAGAAATGAAATTCCTCCCACTTTCTGTGTAGAACAAGGTCTC
TGACAGTATTGATTCATGGAAGTACTAATGGACTTAGAAAACATTAAGAGAATGTCATTTCTCATAGTGTTTCTGTTTCTGAAAATGAAT
CTCCTGAATTATTATCTTTCTCCCTGTTACTTGGCTGGGGAAAGAGATAGAAGCTGTATAAACAAATTCTCTTCCATGCTCAAAGCAAGT
GTTCCATGTGCACAACCTGCTGCAGACTGGGGCCCTTCTCAGTTAATTGGGTTTCACAAGCAATAATTTCTCCACAACAAAAACCACAAC
TTGAAGTGAGTTGAAAAGAGATCAATAGTGGAAACAGTCGCCTCAGTACTTTTTCTTTCTGGATTTCATCTCTAGAAATTTGAAGTGTTT
GAGACAGAGTCCACCCTTTGTGCAAGGCGAGAACCAATGAATGGACTCCTTGTGTGAATTATTGCATCTTCTTCCAAAGCAGGTTCATCA
AGACTTTCACAGAGATTCATTTTTGTTGAGAAGTAAGGGTTAATAGGAGGATAGAATTTGGATCCAAATCTAGTGATAAAAGTGTCCAAG
CAATCAAAAAGTAAGATATTTTAGGGACATACCAACATCTTCCCTTTCTGCTAATTTCATGCTCCAAAGATATGGCAAAAAAAAAAATCA
TAAAAAGTGCTTTTGCCCTACTTGTGTTCTAGTTTTCCCATGGCAGAATTTTGTAATTACATCCAGAATATAGTGTATATTTTGTTCCTC
AAACTTTATTACATTGGATGGATATTGTTGAACTGGGGCACTGGTGCCTATATTCAAGGCTCTTTCCTATCAACGTGTCTGTCCACGATT
TGTTGTGTTTAAAGCTTCATTTTGAAAAATCACTGTCCCCCTGTGGGGTAGTGACTGTATTGTTTTGTTCATGTCTATGTGGGACACATT
GCATCACATGGCAAACCAACTCTCTGTGGATGTGAGATAAGTACTTATAAAACCAGCTTGAAAACATCGTCTTATGTATTATGTCATCCT
GCATCATAATGCAATTATGTGTATCATAACATGCTCATTTAAAAAAAGAGAAACCAGCAAATTCATGTTTGTCCATAGAAGAATGTACTC
AGAACTTTGTGTTGTGAAACGATGAGAACAGACCACCTTTAAGATACCCACCTGCCACTTAAAATGACTTAGTTATAATTAGTAGTAGTC
TAGACGTTGTTCTTGGTGTGTGGGGGTCAATTCTAACGTCATGTTCTTTTGAATAAATCTCTCAGTCATATTTGAAAAAAAAATACATGG
GAATAAAGAAAAATATCATCTTTGGCCAAATCAAGCAGGCATCTTTTTTCTTTTCCTTGACGTTTAGCTCATTATACGTGGTGATTGGAT
CACGAGATCTGTCCGTGTGAAAATACAGAAACATCCTTTAGTTTACAAAACAGTTATTCTAGGCTTGAAGCCTCTGAACAGCAAATTGAA
TAGATGGGCTGCATCTGATTTGCTTTATGGATGTAATTTTACAAAACACTCTTGGGTCTCTGACCCCAGGGAGTTAAGAGTGCCCAGAGG
AGGTCCTACACATTAAAGGATAAAGCCCCCCAGTGATGCTGGCAAGCAAATGTGTTGAGTTCTTAAATCTTCATTTGGTTTTCTGTTCAG
GATTTTAATTGCAAATGAATTTATTTCTCCAGTTTATCTAAAGACCTAATTTCCCAATAGTTTCCTCTGCATTTATATACTCTGTAGTGT
TTAGGCAACCCTGTTATAAGTTTATTAATATTATGTAAGTGTTGTTCTTGTATTTATGTATAGTGTATGTATTGTAAATATACTCAGAGC
TTTTTTCCTTTTACTGTAAAATGGTGATTTTTTTGCCCTATGATAATGTAAAGGGAGACCCTCCTAATGAGATTCTCTCAGAGGATGATT
ATTCCAGTCTATTCTCAGAGATTTAAATGAACAAGTGTTATTGTTTTTAATGGTGTCTCAGACATATTCTGTTGGTGCATTGCTTTTCTG
TATTCAACTTTCCTATGAATTGAGCTGTGAACTGAAATAGAGTTTAAACCTTTAACTGTATGCATTTGTATAATTATCTGAATGAAGGCA

>22898_22898_8_DIS3-KLF12_DIS3_chr13_73345933_ENST00000377780_KLF12_chr13_74420510_ENST00000377669_length(amino acids)=866AA_BP=505
MLKSKTFLKKTRAGGVMKIVREHYLRDDIGCGAPGCAACGGAHEGPALEPQPQDPASSVCPQPHYLLPDTNVLLHQIVSAWRPGTWASVA
SSLRLPGSLETYVEQEQGENANDRNDRAIRVAAKWYNEHLKKMSADNQLQVIFITNDRRNKEKAIEEGIPAFTCEEYVKSLTANPELIDR
LACLSEEGNEIESGKIIFSEHLPLSKLQQGIKSGTYLQGTFRASRENYLEATVWIHGDNEENKEIILQGLKHLNRAVHEDIVAVELLPKS
QWVAPSSVVLHDEGQNEEDVEKEEETERMLKTAVSEKMLKPTGRVVGIIKRNWRPYCGMLSKSDIKESRRHLFTPADKRIPRIRIETRQA
STLEGRRIIVAIDGWPRNSRYPNGHFVRNLGDVGEKETETEVLLLEHDVPHQPFSQAVLSFLPKMPWSITEKDMKNREDLRHLCICSVDP
PGCTDIDDALHCRELENGNLEVGVHIADVSHFIRPGNALDQESARRGTTVYLCEKSPNVHNYPDMEAVPLLLNNVKGEPPEDSLSVDHFQ
TQTEPVDLSINKARTSPTAVSSSPVSMTASASSPSSTSTSSSSSSRLASSPTVITSVSSASSSSTVLTPGPLVASASGVGGQQFLHIIHP
VPPSSPMNLQSNKLSHVHRIPVVVQSVPVVYTAVRSPGNVNNTIVVPLLEDGRGHGKAQMDPRGLSPRQSKSDSDDDDLPNVTLDSVNET
GSTALSIARAVQEVHPSPVSRVRGNRMNNQKFPCSISPFSIESTRRQRRSESPDSRKRRIHRCDFEGCNKVYTKSSHLKAHRRTHTGEKP

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Fusion Gene PPI Analysis for DIS3-KLF12


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DIS3-KLF12


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DIS3-KLF12


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource