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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DIS3L2-DNM1 (FusionGDB2 ID:22901)

Fusion Gene Summary for DIS3L2-DNM1

check button Fusion gene summary
Fusion gene informationFusion gene name: DIS3L2-DNM1
Fusion gene ID: 22901
HgeneTgene
Gene symbol

DIS3L2

DNM1

Gene ID

129563

1759

Gene nameDIS3 like 3'-5' exoribonuclease 2dynamin 1
SynonymsFAM6A|PRLMNS|hDIS3L2DNM|EIEE31
Cytomap

2q37.1

9q34.11

Type of geneprotein-codingprotein-coding
DescriptionDIS3-like exonuclease 2DIS3 mitotic control homolog-like 2family with sequence similarity 6, member Adynamin-1
Modification date2020031320200327
UniProtAcc

Q8IYB7

O00429

Ensembl transtripts involved in fusion geneENST00000325385, ENST00000409307, 
ENST00000273009, ENST00000360410, 
ENST00000409401, ENST00000470087, 
ENST00000493925, ENST00000341179, 
ENST00000372923, ENST00000393594, 
ENST00000475805, ENST00000486160, 
Fusion gene scores* DoF score27 X 9 X 12=29164 X 5 X 4=80
# samples 255
** MAII scorelog2(25/2916*10)=-3.54399071966485
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/80*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DIS3L2 [Title/Abstract] AND DNM1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDIS3L2(233128150)-DNM1(130996300), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneDIS3L2

GO:0010587

miRNA catabolic process

24141620


check buttonFusion gene breakpoints across DIS3L2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across DNM1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-G9-A9S7-01ADIS3L2chr2

233128150

-DNM1chr9

130996300

+
ChimerDB4PRADTCGA-G9-A9S7-01ADIS3L2chr2

233128150

+DNM1chr9

130996300

+
ChimerDB4PRADTCGA-G9-A9S7DIS3L2chr2

233128150

+DNM1chr9

130996299

+
ChimerDB4PRADTCGA-G9-A9S7DIS3L2chr2

233128150

+DNM1chr9

130996300

+


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Fusion Gene ORF analysis for DIS3L2-DNM1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000325385ENST00000493925DIS3L2chr2

233128150

+DNM1chr9

130996300

+
5CDS-intronENST00000325385ENST00000493925DIS3L2chr2

233128150

+DNM1chr9

130996299

+
5CDS-intronENST00000409307ENST00000493925DIS3L2chr2

233128150

+DNM1chr9

130996300

+
5CDS-intronENST00000409307ENST00000493925DIS3L2chr2

233128150

+DNM1chr9

130996299

+
In-frameENST00000325385ENST00000341179DIS3L2chr2

233128150

+DNM1chr9

130996300

+
In-frameENST00000325385ENST00000341179DIS3L2chr2

233128150

+DNM1chr9

130996299

+
In-frameENST00000325385ENST00000372923DIS3L2chr2

233128150

+DNM1chr9

130996300

+
In-frameENST00000325385ENST00000372923DIS3L2chr2

233128150

+DNM1chr9

130996299

+
In-frameENST00000325385ENST00000393594DIS3L2chr2

233128150

+DNM1chr9

130996300

+
In-frameENST00000325385ENST00000393594DIS3L2chr2

233128150

+DNM1chr9

130996299

+
In-frameENST00000325385ENST00000475805DIS3L2chr2

233128150

+DNM1chr9

130996300

+
In-frameENST00000325385ENST00000475805DIS3L2chr2

233128150

+DNM1chr9

130996299

+
In-frameENST00000325385ENST00000486160DIS3L2chr2

233128150

+DNM1chr9

130996300

+
In-frameENST00000325385ENST00000486160DIS3L2chr2

233128150

+DNM1chr9

130996299

+
In-frameENST00000409307ENST00000341179DIS3L2chr2

233128150

+DNM1chr9

130996300

+
In-frameENST00000409307ENST00000341179DIS3L2chr2

233128150

+DNM1chr9

130996299

+
In-frameENST00000409307ENST00000372923DIS3L2chr2

233128150

+DNM1chr9

130996300

+
In-frameENST00000409307ENST00000372923DIS3L2chr2

233128150

+DNM1chr9

130996299

+
In-frameENST00000409307ENST00000393594DIS3L2chr2

233128150

+DNM1chr9

130996300

+
In-frameENST00000409307ENST00000393594DIS3L2chr2

233128150

+DNM1chr9

130996299

+
In-frameENST00000409307ENST00000475805DIS3L2chr2

233128150

+DNM1chr9

130996300

+
In-frameENST00000409307ENST00000475805DIS3L2chr2

233128150

+DNM1chr9

130996299

+
In-frameENST00000409307ENST00000486160DIS3L2chr2

233128150

+DNM1chr9

130996300

+
In-frameENST00000409307ENST00000486160DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000273009ENST00000341179DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000273009ENST00000341179DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000273009ENST00000372923DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000273009ENST00000372923DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000273009ENST00000393594DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000273009ENST00000393594DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000273009ENST00000475805DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000273009ENST00000475805DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000273009ENST00000486160DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000273009ENST00000486160DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000360410ENST00000341179DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000360410ENST00000341179DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000360410ENST00000372923DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000360410ENST00000372923DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000360410ENST00000393594DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000360410ENST00000393594DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000360410ENST00000475805DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000360410ENST00000475805DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000360410ENST00000486160DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000360410ENST00000486160DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000409401ENST00000341179DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000409401ENST00000341179DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000409401ENST00000372923DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000409401ENST00000372923DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000409401ENST00000393594DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000409401ENST00000393594DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000409401ENST00000475805DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000409401ENST00000475805DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000409401ENST00000486160DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000409401ENST00000486160DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000470087ENST00000341179DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000470087ENST00000341179DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000470087ENST00000372923DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000470087ENST00000372923DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000470087ENST00000393594DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000470087ENST00000393594DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000470087ENST00000475805DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000470087ENST00000475805DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-3CDSENST00000470087ENST00000486160DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-3CDSENST00000470087ENST00000486160DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-intronENST00000273009ENST00000493925DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-intronENST00000273009ENST00000493925DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-intronENST00000360410ENST00000493925DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-intronENST00000360410ENST00000493925DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-intronENST00000409401ENST00000493925DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-intronENST00000409401ENST00000493925DIS3L2chr2

233128150

+DNM1chr9

130996299

+
intron-intronENST00000470087ENST00000493925DIS3L2chr2

233128150

+DNM1chr9

130996300

+
intron-intronENST00000470087ENST00000493925DIS3L2chr2

233128150

+DNM1chr9

130996299

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000325385DIS3L2chr2233128150+ENST00000475805DNM1chr9130996300+332519352403155971
ENST00000325385DIS3L2chr2233128150+ENST00000341179DNM1chr9130996300+375519352403155971
ENST00000325385DIS3L2chr2233128150+ENST00000372923DNM1chr9130996300+372919352403194984
ENST00000325385DIS3L2chr2233128150+ENST00000393594DNM1chr9130996300+375719352403155971
ENST00000325385DIS3L2chr2233128150+ENST00000486160DNM1chr9130996300+371819352403194984
ENST00000409307DIS3L2chr2233128150+ENST00000475805DNM1chr9130996300+3049165902879959
ENST00000409307DIS3L2chr2233128150+ENST00000341179DNM1chr9130996300+3479165902879959
ENST00000409307DIS3L2chr2233128150+ENST00000372923DNM1chr9130996300+3453165902918972
ENST00000409307DIS3L2chr2233128150+ENST00000393594DNM1chr9130996300+3481165902879959
ENST00000409307DIS3L2chr2233128150+ENST00000486160DNM1chr9130996300+3442165902918972
ENST00000325385DIS3L2chr2233128150+ENST00000475805DNM1chr9130996299+332519352403155971
ENST00000325385DIS3L2chr2233128150+ENST00000341179DNM1chr9130996299+375519352403155971
ENST00000325385DIS3L2chr2233128150+ENST00000372923DNM1chr9130996299+372919352403194984
ENST00000325385DIS3L2chr2233128150+ENST00000393594DNM1chr9130996299+375719352403155971
ENST00000325385DIS3L2chr2233128150+ENST00000486160DNM1chr9130996299+371819352403194984
ENST00000409307DIS3L2chr2233128150+ENST00000475805DNM1chr9130996299+3049165902879959
ENST00000409307DIS3L2chr2233128150+ENST00000341179DNM1chr9130996299+3479165902879959
ENST00000409307DIS3L2chr2233128150+ENST00000372923DNM1chr9130996299+3453165902918972
ENST00000409307DIS3L2chr2233128150+ENST00000393594DNM1chr9130996299+3481165902879959
ENST00000409307DIS3L2chr2233128150+ENST00000486160DNM1chr9130996299+3442165902918972

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000325385ENST00000475805DIS3L2chr2233128150+DNM1chr9130996300+0.001797220.9982028
ENST00000325385ENST00000341179DIS3L2chr2233128150+DNM1chr9130996300+0.0010449870.998955
ENST00000325385ENST00000372923DIS3L2chr2233128150+DNM1chr9130996300+0.000948290.99905175
ENST00000325385ENST00000393594DIS3L2chr2233128150+DNM1chr9130996300+0.001045340.99895465
ENST00000325385ENST00000486160DIS3L2chr2233128150+DNM1chr9130996300+0.0009755190.9990245
ENST00000409307ENST00000475805DIS3L2chr2233128150+DNM1chr9130996300+0.0014684050.9985316
ENST00000409307ENST00000341179DIS3L2chr2233128150+DNM1chr9130996300+0.0008462370.99915373
ENST00000409307ENST00000372923DIS3L2chr2233128150+DNM1chr9130996300+0.0007488170.9992512
ENST00000409307ENST00000393594DIS3L2chr2233128150+DNM1chr9130996300+0.0008451410.9991548
ENST00000409307ENST00000486160DIS3L2chr2233128150+DNM1chr9130996300+0.0007727190.9992273
ENST00000325385ENST00000475805DIS3L2chr2233128150+DNM1chr9130996299+0.001797220.9982028
ENST00000325385ENST00000341179DIS3L2chr2233128150+DNM1chr9130996299+0.0010449870.998955
ENST00000325385ENST00000372923DIS3L2chr2233128150+DNM1chr9130996299+0.000948290.99905175
ENST00000325385ENST00000393594DIS3L2chr2233128150+DNM1chr9130996299+0.001045340.99895465
ENST00000325385ENST00000486160DIS3L2chr2233128150+DNM1chr9130996299+0.0009755190.9990245
ENST00000409307ENST00000475805DIS3L2chr2233128150+DNM1chr9130996299+0.0014684050.9985316
ENST00000409307ENST00000341179DIS3L2chr2233128150+DNM1chr9130996299+0.0008462370.99915373
ENST00000409307ENST00000372923DIS3L2chr2233128150+DNM1chr9130996299+0.0007488170.9992512
ENST00000409307ENST00000393594DIS3L2chr2233128150+DNM1chr9130996299+0.0008451410.9991548
ENST00000409307ENST00000486160DIS3L2chr2233128150+DNM1chr9130996299+0.0007727190.9992273

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Fusion Genomic Features for DIS3L2-DNM1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DIS3L2chr2233128150+DNM1chr9130996299+1.83E-081
DIS3L2chr2233128150+DNM1chr9130996299+1.83E-081
DIS3L2chr2233128150+DNM1chr9130996299+1.83E-081
DIS3L2chr2233128150+DNM1chr9130996299+1.83E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for DIS3L2-DNM1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:233128150/chr9:130996300)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DIS3L2

Q8IYB7

DNM1

O00429

FUNCTION: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation. {ECO:0000255|HAMAP-Rule:MF_03045, ECO:0000269|PubMed:23756462, ECO:0000269|PubMed:24141620}.FUNCTION: Functions in mitochondrial and peroxisomal division (PubMed:9570752, PubMed:9786947, PubMed:11514614, PubMed:12499366, PubMed:17301055, PubMed:17553808, PubMed:17460227, PubMed:18695047, PubMed:18838687, PubMed:19638400, PubMed:19411255, PubMed:19342591, PubMed:23921378, PubMed:23283981, PubMed:23530241, PubMed:29478834, PubMed:32484300, PubMed:27145208, PubMed:26992161, PubMed:27301544, PubMed:27328748). Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism (PubMed:23530241, PubMed:23584531). The specific recruitment at scission sites is mediated by membrane receptors like MFF, MIEF1 and MIEF2 for mitochondrial membranes (PubMed:23921378, PubMed:23283981, PubMed:29899447). While the recruitment by the membrane receptors is GTP-dependent, the following hydrolysis of GTP induces the dissociation from the receptors and allows DNM1L filaments to curl into closed rings that are probably sufficient to sever a double membrane (PubMed:29899447). Acts downstream of PINK1 to promote mitochondrial fission in a PRKN-dependent manner (PubMed:32484300). Plays an important role in mitochondrial fission during mitosis (PubMed:19411255, PubMed:26992161, PubMed:27301544, PubMed:27328748). Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage (By similarity). Required for normal brain development, including that of cerebellum (PubMed:17460227, PubMed:27145208, PubMed:26992161, PubMed:27301544, PubMed:27328748). Facilitates developmentally regulated apoptosis during neural tube formation (By similarity). Required for a normal rate of cytochrome c release and caspase activation during apoptosis; this requirement may depend upon the cell type and the physiological apoptotic cues (By similarity). Required for formation of endocytic vesicles (PubMed:9570752, PubMed:20688057, PubMed:23792689). Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L) which stimulates its GTPase activity in synaptic vesicles; the function may require its recruitment by MFF to clathrin-containing vesicles (PubMed:17015472, PubMed:23792689). Required for programmed necrosis execution (PubMed:22265414). Rhythmic control of its activity following phosphorylation at Ser-637 is essential for the circadian control of mitochondrial ATP production (PubMed:29478834). {ECO:0000250|UniProtKB:Q8K1M6, ECO:0000269|PubMed:11514614, ECO:0000269|PubMed:12499366, ECO:0000269|PubMed:17015472, ECO:0000269|PubMed:17301055, ECO:0000269|PubMed:17460227, ECO:0000269|PubMed:17553808, ECO:0000269|PubMed:18695047, ECO:0000269|PubMed:18838687, ECO:0000269|PubMed:19342591, ECO:0000269|PubMed:19411255, ECO:0000269|PubMed:19638400, ECO:0000269|PubMed:20688057, ECO:0000269|PubMed:22265414, ECO:0000269|PubMed:23283981, ECO:0000269|PubMed:23530241, ECO:0000269|PubMed:23584531, ECO:0000269|PubMed:23792689, ECO:0000269|PubMed:23921378, ECO:0000269|PubMed:26992161, ECO:0000269|PubMed:27145208, ECO:0000269|PubMed:27301544, ECO:0000269|PubMed:27328748, ECO:0000269|PubMed:29478834, ECO:0000269|PubMed:29899447, ECO:0000269|PubMed:32484300, ECO:0000269|PubMed:9570752, ECO:0000269|PubMed:9786947}.; FUNCTION: [Isoform 1]: Inhibits peroxisomal division when overexpressed. {ECO:0000269|PubMed:12618434}.; FUNCTION: [Isoform 4]: Inhibits peroxisomal division when overexpressed. {ECO:0000269|PubMed:12618434}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

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* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneDNM1chr2:233128150chr9:130996299ENST00000341179923519_625445962.3333333333334DomainPH
TgeneDNM1chr2:233128150chr9:130996299ENST00000341179923659_750445962.3333333333334DomainGED
TgeneDNM1chr2:233128150chr9:130996299ENST00000372923922519_625445865.0DomainPH
TgeneDNM1chr2:233128150chr9:130996299ENST00000372923922659_750445865.0DomainGED
TgeneDNM1chr2:233128150chr9:130996299ENST00000393594923519_625445975.6666666666666DomainPH
TgeneDNM1chr2:233128150chr9:130996299ENST00000393594923659_750445975.6666666666666DomainGED
TgeneDNM1chr2:233128150chr9:130996299ENST00000475805923519_625445819.0DomainPH
TgeneDNM1chr2:233128150chr9:130996299ENST00000475805923659_750445819.0DomainGED
TgeneDNM1chr2:233128150chr9:130996299ENST00000486160922519_625445865.0DomainPH
TgeneDNM1chr2:233128150chr9:130996299ENST00000486160922659_750445865.0DomainGED
TgeneDNM1chr2:233128150chr9:130996300ENST00000341179923519_625445962.3333333333334DomainPH
TgeneDNM1chr2:233128150chr9:130996300ENST00000341179923659_750445962.3333333333334DomainGED
TgeneDNM1chr2:233128150chr9:130996300ENST00000372923922519_625445865.0DomainPH
TgeneDNM1chr2:233128150chr9:130996300ENST00000372923922659_750445865.0DomainGED
TgeneDNM1chr2:233128150chr9:130996300ENST00000393594923519_625445975.6666666666666DomainPH
TgeneDNM1chr2:233128150chr9:130996300ENST00000393594923659_750445975.6666666666666DomainGED
TgeneDNM1chr2:233128150chr9:130996300ENST00000475805923519_625445819.0DomainPH
TgeneDNM1chr2:233128150chr9:130996300ENST00000475805923659_750445819.0DomainGED
TgeneDNM1chr2:233128150chr9:130996300ENST00000486160922519_625445865.0DomainPH
TgeneDNM1chr2:233128150chr9:130996300ENST00000486160922659_750445865.0DomainGED

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneDNM1chr2:233128150chr9:130996299ENST0000034117992328_294445962.3333333333334DomainDynamin-type G
TgeneDNM1chr2:233128150chr9:130996299ENST0000037292392228_294445865.0DomainDynamin-type G
TgeneDNM1chr2:233128150chr9:130996299ENST0000039359492328_294445975.6666666666666DomainDynamin-type G
TgeneDNM1chr2:233128150chr9:130996299ENST0000047580592328_294445819.0DomainDynamin-type G
TgeneDNM1chr2:233128150chr9:130996299ENST0000048616092228_294445865.0DomainDynamin-type G
TgeneDNM1chr2:233128150chr9:130996300ENST0000034117992328_294445962.3333333333334DomainDynamin-type G
TgeneDNM1chr2:233128150chr9:130996300ENST0000037292392228_294445865.0DomainDynamin-type G
TgeneDNM1chr2:233128150chr9:130996300ENST0000039359492328_294445975.6666666666666DomainDynamin-type G
TgeneDNM1chr2:233128150chr9:130996300ENST0000047580592328_294445819.0DomainDynamin-type G
TgeneDNM1chr2:233128150chr9:130996300ENST0000048616092228_294445865.0DomainDynamin-type G
TgeneDNM1chr2:233128150chr9:130996299ENST00000341179923136_140445962.3333333333334Nucleotide bindingGTP
TgeneDNM1chr2:233128150chr9:130996299ENST00000372923922136_140445865.0Nucleotide bindingGTP
TgeneDNM1chr2:233128150chr9:130996299ENST00000393594923136_140445975.6666666666666Nucleotide bindingGTP
TgeneDNM1chr2:233128150chr9:130996299ENST00000475805923136_140445819.0Nucleotide bindingGTP
TgeneDNM1chr2:233128150chr9:130996299ENST00000486160922136_140445865.0Nucleotide bindingGTP
TgeneDNM1chr2:233128150chr9:130996300ENST00000341179923136_140445962.3333333333334Nucleotide bindingGTP
TgeneDNM1chr2:233128150chr9:130996300ENST00000372923922136_140445865.0Nucleotide bindingGTP
TgeneDNM1chr2:233128150chr9:130996300ENST00000393594923136_140445975.6666666666666Nucleotide bindingGTP
TgeneDNM1chr2:233128150chr9:130996300ENST00000475805923136_140445819.0Nucleotide bindingGTP
TgeneDNM1chr2:233128150chr9:130996300ENST00000486160922136_140445865.0Nucleotide bindingGTP
TgeneDNM1chr2:233128150chr9:130996299ENST00000341179923136_139445962.3333333333334RegionG3 motif
TgeneDNM1chr2:233128150chr9:130996299ENST00000341179923205_208445962.3333333333334RegionG4 motif
TgeneDNM1chr2:233128150chr9:130996299ENST00000341179923235_238445962.3333333333334RegionG5 motif
TgeneDNM1chr2:233128150chr9:130996299ENST0000034117992338_45445962.3333333333334RegionG1 motif
TgeneDNM1chr2:233128150chr9:130996299ENST0000034117992364_66445962.3333333333334RegionG2 motif
TgeneDNM1chr2:233128150chr9:130996299ENST00000372923922136_139445865.0RegionG3 motif
TgeneDNM1chr2:233128150chr9:130996299ENST00000372923922205_208445865.0RegionG4 motif
TgeneDNM1chr2:233128150chr9:130996299ENST00000372923922235_238445865.0RegionG5 motif
TgeneDNM1chr2:233128150chr9:130996299ENST0000037292392238_45445865.0RegionG1 motif
TgeneDNM1chr2:233128150chr9:130996299ENST0000037292392264_66445865.0RegionG2 motif
TgeneDNM1chr2:233128150chr9:130996299ENST00000393594923136_139445975.6666666666666RegionG3 motif
TgeneDNM1chr2:233128150chr9:130996299ENST00000393594923205_208445975.6666666666666RegionG4 motif
TgeneDNM1chr2:233128150chr9:130996299ENST00000393594923235_238445975.6666666666666RegionG5 motif
TgeneDNM1chr2:233128150chr9:130996299ENST0000039359492338_45445975.6666666666666RegionG1 motif
TgeneDNM1chr2:233128150chr9:130996299ENST0000039359492364_66445975.6666666666666RegionG2 motif
TgeneDNM1chr2:233128150chr9:130996299ENST00000475805923136_139445819.0RegionG3 motif
TgeneDNM1chr2:233128150chr9:130996299ENST00000475805923205_208445819.0RegionG4 motif
TgeneDNM1chr2:233128150chr9:130996299ENST00000475805923235_238445819.0RegionG5 motif
TgeneDNM1chr2:233128150chr9:130996299ENST0000047580592338_45445819.0RegionG1 motif
TgeneDNM1chr2:233128150chr9:130996299ENST0000047580592364_66445819.0RegionG2 motif
TgeneDNM1chr2:233128150chr9:130996299ENST00000486160922136_139445865.0RegionG3 motif
TgeneDNM1chr2:233128150chr9:130996299ENST00000486160922205_208445865.0RegionG4 motif
TgeneDNM1chr2:233128150chr9:130996299ENST00000486160922235_238445865.0RegionG5 motif
TgeneDNM1chr2:233128150chr9:130996299ENST0000048616092238_45445865.0RegionG1 motif
TgeneDNM1chr2:233128150chr9:130996299ENST0000048616092264_66445865.0RegionG2 motif
TgeneDNM1chr2:233128150chr9:130996300ENST00000341179923136_139445962.3333333333334RegionG3 motif
TgeneDNM1chr2:233128150chr9:130996300ENST00000341179923205_208445962.3333333333334RegionG4 motif
TgeneDNM1chr2:233128150chr9:130996300ENST00000341179923235_238445962.3333333333334RegionG5 motif
TgeneDNM1chr2:233128150chr9:130996300ENST0000034117992338_45445962.3333333333334RegionG1 motif
TgeneDNM1chr2:233128150chr9:130996300ENST0000034117992364_66445962.3333333333334RegionG2 motif
TgeneDNM1chr2:233128150chr9:130996300ENST00000372923922136_139445865.0RegionG3 motif
TgeneDNM1chr2:233128150chr9:130996300ENST00000372923922205_208445865.0RegionG4 motif
TgeneDNM1chr2:233128150chr9:130996300ENST00000372923922235_238445865.0RegionG5 motif
TgeneDNM1chr2:233128150chr9:130996300ENST0000037292392238_45445865.0RegionG1 motif
TgeneDNM1chr2:233128150chr9:130996300ENST0000037292392264_66445865.0RegionG2 motif
TgeneDNM1chr2:233128150chr9:130996300ENST00000393594923136_139445975.6666666666666RegionG3 motif
TgeneDNM1chr2:233128150chr9:130996300ENST00000393594923205_208445975.6666666666666RegionG4 motif
TgeneDNM1chr2:233128150chr9:130996300ENST00000393594923235_238445975.6666666666666RegionG5 motif
TgeneDNM1chr2:233128150chr9:130996300ENST0000039359492338_45445975.6666666666666RegionG1 motif
TgeneDNM1chr2:233128150chr9:130996300ENST0000039359492364_66445975.6666666666666RegionG2 motif
TgeneDNM1chr2:233128150chr9:130996300ENST00000475805923136_139445819.0RegionG3 motif
TgeneDNM1chr2:233128150chr9:130996300ENST00000475805923205_208445819.0RegionG4 motif
TgeneDNM1chr2:233128150chr9:130996300ENST00000475805923235_238445819.0RegionG5 motif
TgeneDNM1chr2:233128150chr9:130996300ENST0000047580592338_45445819.0RegionG1 motif
TgeneDNM1chr2:233128150chr9:130996300ENST0000047580592364_66445819.0RegionG2 motif
TgeneDNM1chr2:233128150chr9:130996300ENST00000486160922136_139445865.0RegionG3 motif
TgeneDNM1chr2:233128150chr9:130996300ENST00000486160922205_208445865.0RegionG4 motif
TgeneDNM1chr2:233128150chr9:130996300ENST00000486160922235_238445865.0RegionG5 motif
TgeneDNM1chr2:233128150chr9:130996300ENST0000048616092238_45445865.0RegionG1 motif
TgeneDNM1chr2:233128150chr9:130996300ENST0000048616092264_66445865.0RegionG2 motif


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Fusion Gene Sequence for DIS3L2-DNM1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>22901_22901_1_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996299_ENST00000341179_length(transcript)=3755nt_BP=1935nt
TTTCGCCCTTGTCGCAGCTGAACCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCAC
CGTCGCTCTCTAGAACGCCGCGCCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAA
ACGCGAATGACAACAGAGCTGCTCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAG
CCAATAATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATT
GGTGCTTCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGAT
GTTTCAGAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCG
GATGGTGATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAG
GAGCATTGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACAC
CATCTCCCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGA
CATGGCATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCG
GTTACAAAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATC
TTGGAGAAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTT
TCTCCCTCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAAC
ACACTGTTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAA
ATTGAGCCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGC
CTGCCATGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGA
GACCTCGATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCG
GAGGGATCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTG
TGTGAGGAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGAT
GAATGGTTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATC
CCTGCGAAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAG
TTACGCCAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTG
ACCACCCACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCAT
GAGGACTTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTC
ATCCGCAAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTG
TCCTGGTACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATG
TCGAGCAAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAG
GAGGAGGTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAG
GAGAATGGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATG
GCCATTGTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAG
CTGCTGGCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGC
ATGTACCACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGAC
TCCTGGCTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCA
GCCCGGCCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGG
GCTTCCCCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGAATCACTATCAGTGAC
CCCTGAGGAGCGTCAGCCATGCCGATCGGGTCAGGCAAGTCCATCCCGTCCTGAGAGCCCCAGGCCCCCCTTCGACCTCTAAACAGATCC
CTCCTCTTCTCGGAGACCTCCCTTTCCAAGCCTGCCTGGACGGCTGTTCTGTGACTTGACAGTGGCTCCCCCAGCCCCAAAGCCAGCCCC
CTTCATCTGTGACTTAATCTGTTGTAGTGGTGAGCTGATACATTCAGGTGTGACCGTTGGTGAAAACTTGTGCCCCTTCTGTGGTATGCC
CTTGCCCTGTTCTATAAATATCTATAAATACTCATATATATACACACCTACACATGGCCAACCGCCTCGCCTCTAGCGCTGGGAATCAGT
CACTGTGCTATCCTTGTGGAGTCTTGTGGCCCAACTACCAGAGAACGCTGTCCCCCGACATCCCACTCCAAAGTGTGCCACCTCCAGTGA
GCCTCCTTGTCATGCCCGGCCTGTGGACAGCCAGCCCCCGCCATCCCTCCCACCCCCTACCAAGCATGGGGGTGCTGTGCAGGCAGCCGT

>22901_22901_1_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996299_ENST00000341179_length(amino acids)=971AA_BP=562
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS
SEVLECLPQGLPWTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQ
KVVPMLPRLLCEELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQA
VLNLHGIAKQLRQQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKK
TSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY
RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMI
NNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT

--------------------------------------------------------------
>22901_22901_2_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996299_ENST00000372923_length(transcript)=3729nt_BP=1935nt
TTTCGCCCTTGTCGCAGCTGAACCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCAC
CGTCGCTCTCTAGAACGCCGCGCCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAA
ACGCGAATGACAACAGAGCTGCTCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAG
CCAATAATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATT
GGTGCTTCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGAT
GTTTCAGAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCG
GATGGTGATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAG
GAGCATTGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACAC
CATCTCCCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGA
CATGGCATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCG
GTTACAAAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATC
TTGGAGAAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTT
TCTCCCTCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAAC
ACACTGTTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAA
ATTGAGCCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGC
CTGCCATGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGA
GACCTCGATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCG
GAGGGATCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTG
TGTGAGGAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGAT
GAATGGTTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATC
CCTGCGAAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAG
TTACGCCAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTG
ACCACCCACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCAT
GAGGACTTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTC
ATCCGCAAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTG
TCCTGGTACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATG
TCGAGCAAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAG
GAGGAGGTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAG
GAGAATGGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATG
GCCATTGTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAG
CTGCTGGCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGC
ATGTACCACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGAC
TCCTGGCTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCA
GCCCGGCCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGG
GCTTCCCCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGCCGATCGGGTCAGGCA
AGTCCATCCCGTCCTGAGAGCCCCAGGCCCCCCTTCGACCTCTAAACAGATCCCTCCTCTTCTCGGAGACCTCCCTTTCCAAGCCTGCCT
GGACGGCTGTTCTGTGACTTGACAGTGGCTCCCCCAGCCCCAAAGCCAGCCCCCTTCATCTGTGACTTAATCTGTTGTAGTGGTGAGCTG
ATACATTCAGGTGTGACCGTTGGTGAAAACTTGTGCCCCTTCTGTGGTATGCCCTTGCCCTGTTCTATAAATATCTATAAATACTCATAT
ATATACACACCTACACATGGCCAACCGCCTCGCCTCTAGCGCTGGGAATCAGTCACTGTGCTATCCTTGTGGAGTCTTGTGGCCCAACTA
CCAGAGAACGCTGTCCCCCGACATCCCACTCCAAAGTGTGCCACCTCCAGTGAGCCTCCTTGTCATGCCCGGCCTGTGGACAGCCAGCCC
CCGCCATCCCTCCCACCCCCTACCAAGCATGGGGGTGCTGTGCAGGCAGCCGTGTGGCCTGACAGTTTCTACCAGTCCTGCTGTCCCTCG

>22901_22901_2_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996299_ENST00000372923_length(amino acids)=984AA_BP=562
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS
SEVLECLPQGLPWTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQ
KVVPMLPRLLCEELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQA
VLNLHGIAKQLRQQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKK
TSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY
RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMI
NNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT

--------------------------------------------------------------
>22901_22901_3_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996299_ENST00000393594_length(transcript)=3757nt_BP=1935nt
TTTCGCCCTTGTCGCAGCTGAACCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCAC
CGTCGCTCTCTAGAACGCCGCGCCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAA
ACGCGAATGACAACAGAGCTGCTCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAG
CCAATAATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATT
GGTGCTTCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGAT
GTTTCAGAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCG
GATGGTGATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAG
GAGCATTGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACAC
CATCTCCCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGA
CATGGCATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCG
GTTACAAAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATC
TTGGAGAAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTT
TCTCCCTCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAAC
ACACTGTTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAA
ATTGAGCCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGC
CTGCCATGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGA
GACCTCGATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCG
GAGGGATCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTG
TGTGAGGAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGAT
GAATGGTTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATC
CCTGCGAAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAG
TTACGCCAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTG
ACCACCCACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCAT
GAGGACTTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTC
ATCCGCAAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTG
TCCTGGTACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATG
TCGAGCAAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAG
GAGGAGGTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAG
GAGAATGGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATG
GCCATTGTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAG
CTGCTGGCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGC
ATGTACCACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGAC
TCCTGGCTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCA
GCCCGGCCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGG
GCTTCCCCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGAATCACTATCAGTGAC
CCCTGAGGAGCGTCAGCCATGCCGATCGGGTCAGGCAAGTCCATCCCGTCCTGAGAGCCCCAGGCCCCCCTTCGACCTCTAAACAGATCC
CTCCTCTTCTCGGAGACCTCCCTTTCCAAGCCTGCCTGGACGGCTGTTCTGTGACTTGACAGTGGCTCCCCCAGCCCCAAAGCCAGCCCC
CTTCATCTGTGACTTAATCTGTTGTAGTGGTGAGCTGATACATTCAGGTGTGACCGTTGGTGAAAACTTGTGCCCCTTCTGTGGTATGCC
CTTGCCCTGTTCTATAAATATCTATAAATACTCATATATATACACACCTACACATGGCCAACCGCCTCGCCTCTAGCGCTGGGAATCAGT
CACTGTGCTATCCTTGTGGAGTCTTGTGGCCCAACTACCAGAGAACGCTGTCCCCCGACATCCCACTCCAAAGTGTGCCACCTCCAGTGA
GCCTCCTTGTCATGCCCGGCCTGTGGACAGCCAGCCCCCGCCATCCCTCCCACCCCCTACCAAGCATGGGGGTGCTGTGCAGGCAGCCGT

>22901_22901_3_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996299_ENST00000393594_length(amino acids)=971AA_BP=562
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS
SEVLECLPQGLPWTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQ
KVVPMLPRLLCEELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQA
VLNLHGIAKQLRQQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKK
TSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY
RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMI
NNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT

--------------------------------------------------------------
>22901_22901_4_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996299_ENST00000475805_length(transcript)=3325nt_BP=1935nt
TTTCGCCCTTGTCGCAGCTGAACCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCAC
CGTCGCTCTCTAGAACGCCGCGCCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAA
ACGCGAATGACAACAGAGCTGCTCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAG
CCAATAATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATT
GGTGCTTCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGAT
GTTTCAGAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCG
GATGGTGATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAG
GAGCATTGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACAC
CATCTCCCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGA
CATGGCATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCG
GTTACAAAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATC
TTGGAGAAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTT
TCTCCCTCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAAC
ACACTGTTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAA
ATTGAGCCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGC
CTGCCATGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGA
GACCTCGATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCG
GAGGGATCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTG
TGTGAGGAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGAT
GAATGGTTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATC
CCTGCGAAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAG
TTACGCCAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTG
ACCACCCACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCAT
GAGGACTTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTC
ATCCGCAAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTG
TCCTGGTACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATG
TCGAGCAAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAG
GAGGAGGTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAG
GAGAATGGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATG
GCCATTGTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAG
CTGCTGGCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGC
ATGTACCACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGAC
TCCTGGCTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCA
GCCCGGCCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGG
GCTTCCCCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGAATCACTATCAGTGAC
CCCTGAGGAGCGTCAGCCATGGAAGGGCCCAGCCTCACCTACGAGACCTGCAGCCCCCCGACCAGCTGAGGCTCCCCTCTTAGACTTATA

>22901_22901_4_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996299_ENST00000475805_length(amino acids)=971AA_BP=562
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS
SEVLECLPQGLPWTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQ
KVVPMLPRLLCEELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQA
VLNLHGIAKQLRQQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKK
TSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY
RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMI
NNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT

--------------------------------------------------------------
>22901_22901_5_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996299_ENST00000486160_length(transcript)=3718nt_BP=1935nt
TTTCGCCCTTGTCGCAGCTGAACCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCAC
CGTCGCTCTCTAGAACGCCGCGCCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAA
ACGCGAATGACAACAGAGCTGCTCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAG
CCAATAATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATT
GGTGCTTCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGAT
GTTTCAGAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCG
GATGGTGATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAG
GAGCATTGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACAC
CATCTCCCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGA
CATGGCATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCG
GTTACAAAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATC
TTGGAGAAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTT
TCTCCCTCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAAC
ACACTGTTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAA
ATTGAGCCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGC
CTGCCATGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGA
GACCTCGATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCG
GAGGGATCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTG
TGTGAGGAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGAT
GAATGGTTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATC
CCTGCGAAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAG
TTACGCCAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTG
ACCACCCACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCAT
GAGGACTTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTC
ATCCGCAAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTG
TCCTGGTACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATG
TCGAGCAAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAG
GAGGAGGTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAG
GAGAATGGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATG
GCCATTGTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAG
CTGCTGGCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGC
ATGTACCACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGAC
TCCTGGCTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCA
GCCCGGCCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGG
GCTTCCCCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGCCGATCGGGTCAGGCA
AGTCCATCCCGTCCTGAGAGCCCCAGGCCCCCCTTCGACCTCTAAACAGATCCCTCCTCTTCTCGGAGACCTCCCTTTCCAAGCCTGCCT
GGACGGCTGTTCTGTGACTTGACAGTGGCTCCCCCAGCCCCAAAGCCAGCCCCCTTCATCTGTGACTTAATCTGTTGTAGTGGTGAGCTG
ATACATTCAGGTGTGACCGTTGGTGAAAACTTGTGCCCCTTCTGTGGTATGCCCTTGCCCTGTTCTATAAATATCTATAAATACTCATAT
ATATACACACCTACACATGGCCAACCGCCTCGCCTCTAGCGCTGGGAATCAGTCACTGTGCTATCCTTGTGGAGTCTTGTGGCCCAACTA
CCAGAGAACGCTGTCCCCCGACATCCCACTCCAAAGTGTGCCACCTCCAGTGAGCCTCCTTGTCATGCCCGGCCTGTGGACAGCCAGCCC
CCGCCATCCCTCCCACCCCCTACCAAGCATGGGGGTGCTGTGCAGGCAGCCGTGTGGCCTGACAGTTTCTACCAGTCCTGCTGTCCCTCG

>22901_22901_5_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996299_ENST00000486160_length(amino acids)=984AA_BP=562
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS
SEVLECLPQGLPWTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQ
KVVPMLPRLLCEELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQA
VLNLHGIAKQLRQQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKK
TSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY
RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMI
NNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT

--------------------------------------------------------------
>22901_22901_6_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996300_ENST00000341179_length(transcript)=3755nt_BP=1935nt
TTTCGCCCTTGTCGCAGCTGAACCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCAC
CGTCGCTCTCTAGAACGCCGCGCCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAA
ACGCGAATGACAACAGAGCTGCTCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAG
CCAATAATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATT
GGTGCTTCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGAT
GTTTCAGAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCG
GATGGTGATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAG
GAGCATTGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACAC
CATCTCCCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGA
CATGGCATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCG
GTTACAAAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATC
TTGGAGAAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTT
TCTCCCTCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAAC
ACACTGTTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAA
ATTGAGCCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGC
CTGCCATGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGA
GACCTCGATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCG
GAGGGATCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTG
TGTGAGGAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGAT
GAATGGTTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATC
CCTGCGAAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAG
TTACGCCAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTG
ACCACCCACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCAT
GAGGACTTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTC
ATCCGCAAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTG
TCCTGGTACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATG
TCGAGCAAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAG
GAGGAGGTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAG
GAGAATGGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATG
GCCATTGTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAG
CTGCTGGCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGC
ATGTACCACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGAC
TCCTGGCTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCA
GCCCGGCCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGG
GCTTCCCCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGAATCACTATCAGTGAC
CCCTGAGGAGCGTCAGCCATGCCGATCGGGTCAGGCAAGTCCATCCCGTCCTGAGAGCCCCAGGCCCCCCTTCGACCTCTAAACAGATCC
CTCCTCTTCTCGGAGACCTCCCTTTCCAAGCCTGCCTGGACGGCTGTTCTGTGACTTGACAGTGGCTCCCCCAGCCCCAAAGCCAGCCCC
CTTCATCTGTGACTTAATCTGTTGTAGTGGTGAGCTGATACATTCAGGTGTGACCGTTGGTGAAAACTTGTGCCCCTTCTGTGGTATGCC
CTTGCCCTGTTCTATAAATATCTATAAATACTCATATATATACACACCTACACATGGCCAACCGCCTCGCCTCTAGCGCTGGGAATCAGT
CACTGTGCTATCCTTGTGGAGTCTTGTGGCCCAACTACCAGAGAACGCTGTCCCCCGACATCCCACTCCAAAGTGTGCCACCTCCAGTGA
GCCTCCTTGTCATGCCCGGCCTGTGGACAGCCAGCCCCCGCCATCCCTCCCACCCCCTACCAAGCATGGGGGTGCTGTGCAGGCAGCCGT

>22901_22901_6_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996300_ENST00000341179_length(amino acids)=971AA_BP=562
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS
SEVLECLPQGLPWTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQ
KVVPMLPRLLCEELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQA
VLNLHGIAKQLRQQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKK
TSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY
RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMI
NNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT

--------------------------------------------------------------
>22901_22901_7_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996300_ENST00000372923_length(transcript)=3729nt_BP=1935nt
TTTCGCCCTTGTCGCAGCTGAACCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCAC
CGTCGCTCTCTAGAACGCCGCGCCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAA
ACGCGAATGACAACAGAGCTGCTCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAG
CCAATAATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATT
GGTGCTTCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGAT
GTTTCAGAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCG
GATGGTGATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAG
GAGCATTGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACAC
CATCTCCCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGA
CATGGCATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCG
GTTACAAAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATC
TTGGAGAAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTT
TCTCCCTCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAAC
ACACTGTTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAA
ATTGAGCCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGC
CTGCCATGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGA
GACCTCGATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCG
GAGGGATCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTG
TGTGAGGAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGAT
GAATGGTTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATC
CCTGCGAAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAG
TTACGCCAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTG
ACCACCCACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCAT
GAGGACTTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTC
ATCCGCAAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTG
TCCTGGTACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATG
TCGAGCAAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAG
GAGGAGGTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAG
GAGAATGGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATG
GCCATTGTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAG
CTGCTGGCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGC
ATGTACCACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGAC
TCCTGGCTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCA
GCCCGGCCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGG
GCTTCCCCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGCCGATCGGGTCAGGCA
AGTCCATCCCGTCCTGAGAGCCCCAGGCCCCCCTTCGACCTCTAAACAGATCCCTCCTCTTCTCGGAGACCTCCCTTTCCAAGCCTGCCT
GGACGGCTGTTCTGTGACTTGACAGTGGCTCCCCCAGCCCCAAAGCCAGCCCCCTTCATCTGTGACTTAATCTGTTGTAGTGGTGAGCTG
ATACATTCAGGTGTGACCGTTGGTGAAAACTTGTGCCCCTTCTGTGGTATGCCCTTGCCCTGTTCTATAAATATCTATAAATACTCATAT
ATATACACACCTACACATGGCCAACCGCCTCGCCTCTAGCGCTGGGAATCAGTCACTGTGCTATCCTTGTGGAGTCTTGTGGCCCAACTA
CCAGAGAACGCTGTCCCCCGACATCCCACTCCAAAGTGTGCCACCTCCAGTGAGCCTCCTTGTCATGCCCGGCCTGTGGACAGCCAGCCC
CCGCCATCCCTCCCACCCCCTACCAAGCATGGGGGTGCTGTGCAGGCAGCCGTGTGGCCTGACAGTTTCTACCAGTCCTGCTGTCCCTCG

>22901_22901_7_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996300_ENST00000372923_length(amino acids)=984AA_BP=562
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS
SEVLECLPQGLPWTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQ
KVVPMLPRLLCEELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQA
VLNLHGIAKQLRQQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKK
TSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY
RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMI
NNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT

--------------------------------------------------------------
>22901_22901_8_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996300_ENST00000393594_length(transcript)=3757nt_BP=1935nt
TTTCGCCCTTGTCGCAGCTGAACCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCAC
CGTCGCTCTCTAGAACGCCGCGCCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAA
ACGCGAATGACAACAGAGCTGCTCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAG
CCAATAATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATT
GGTGCTTCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGAT
GTTTCAGAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCG
GATGGTGATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAG
GAGCATTGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACAC
CATCTCCCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGA
CATGGCATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCG
GTTACAAAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATC
TTGGAGAAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTT
TCTCCCTCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAAC
ACACTGTTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAA
ATTGAGCCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGC
CTGCCATGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGA
GACCTCGATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCG
GAGGGATCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTG
TGTGAGGAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGAT
GAATGGTTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATC
CCTGCGAAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAG
TTACGCCAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTG
ACCACCCACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCAT
GAGGACTTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTC
ATCCGCAAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTG
TCCTGGTACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATG
TCGAGCAAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAG
GAGGAGGTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAG
GAGAATGGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATG
GCCATTGTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAG
CTGCTGGCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGC
ATGTACCACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGAC
TCCTGGCTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCA
GCCCGGCCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGG
GCTTCCCCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGAATCACTATCAGTGAC
CCCTGAGGAGCGTCAGCCATGCCGATCGGGTCAGGCAAGTCCATCCCGTCCTGAGAGCCCCAGGCCCCCCTTCGACCTCTAAACAGATCC
CTCCTCTTCTCGGAGACCTCCCTTTCCAAGCCTGCCTGGACGGCTGTTCTGTGACTTGACAGTGGCTCCCCCAGCCCCAAAGCCAGCCCC
CTTCATCTGTGACTTAATCTGTTGTAGTGGTGAGCTGATACATTCAGGTGTGACCGTTGGTGAAAACTTGTGCCCCTTCTGTGGTATGCC
CTTGCCCTGTTCTATAAATATCTATAAATACTCATATATATACACACCTACACATGGCCAACCGCCTCGCCTCTAGCGCTGGGAATCAGT
CACTGTGCTATCCTTGTGGAGTCTTGTGGCCCAACTACCAGAGAACGCTGTCCCCCGACATCCCACTCCAAAGTGTGCCACCTCCAGTGA
GCCTCCTTGTCATGCCCGGCCTGTGGACAGCCAGCCCCCGCCATCCCTCCCACCCCCTACCAAGCATGGGGGTGCTGTGCAGGCAGCCGT

>22901_22901_8_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996300_ENST00000393594_length(amino acids)=971AA_BP=562
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS
SEVLECLPQGLPWTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQ
KVVPMLPRLLCEELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQA
VLNLHGIAKQLRQQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKK
TSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY
RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMI
NNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT

--------------------------------------------------------------
>22901_22901_9_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996300_ENST00000475805_length(transcript)=3325nt_BP=1935nt
TTTCGCCCTTGTCGCAGCTGAACCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCAC
CGTCGCTCTCTAGAACGCCGCGCCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAA
ACGCGAATGACAACAGAGCTGCTCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAG
CCAATAATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATT
GGTGCTTCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGAT
GTTTCAGAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCG
GATGGTGATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAG
GAGCATTGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACAC
CATCTCCCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGA
CATGGCATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCG
GTTACAAAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATC
TTGGAGAAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTT
TCTCCCTCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAAC
ACACTGTTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAA
ATTGAGCCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGC
CTGCCATGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGA
GACCTCGATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCG
GAGGGATCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTG
TGTGAGGAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGAT
GAATGGTTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATC
CCTGCGAAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAG
TTACGCCAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTG
ACCACCCACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCAT
GAGGACTTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTC
ATCCGCAAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTG
TCCTGGTACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATG
TCGAGCAAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAG
GAGGAGGTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAG
GAGAATGGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATG
GCCATTGTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAG
CTGCTGGCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGC
ATGTACCACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGAC
TCCTGGCTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCA
GCCCGGCCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGG
GCTTCCCCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGAATCACTATCAGTGAC
CCCTGAGGAGCGTCAGCCATGGAAGGGCCCAGCCTCACCTACGAGACCTGCAGCCCCCCGACCAGCTGAGGCTCCCCTCTTAGACTTATA

>22901_22901_9_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996300_ENST00000475805_length(amino acids)=971AA_BP=562
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS
SEVLECLPQGLPWTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQ
KVVPMLPRLLCEELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQA
VLNLHGIAKQLRQQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKK
TSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY
RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMI
NNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT

--------------------------------------------------------------
>22901_22901_10_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996300_ENST00000486160_length(transcript)=3718nt_BP=1935nt
TTTCGCCCTTGTCGCAGCTGAACCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCAC
CGTCGCTCTCTAGAACGCCGCGCCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAA
ACGCGAATGACAACAGAGCTGCTCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAG
CCAATAATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATT
GGTGCTTCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGAT
GTTTCAGAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCG
GATGGTGATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAG
GAGCATTGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACAC
CATCTCCCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGA
CATGGCATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCG
GTTACAAAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATC
TTGGAGAAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTT
TCTCCCTCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAAC
ACACTGTTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAA
ATTGAGCCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGC
CTGCCATGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGA
GACCTCGATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCG
GAGGGATCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTG
TGTGAGGAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGAT
GAATGGTTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATC
CCTGCGAAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAG
TTACGCCAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTG
ACCACCCACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCAT
GAGGACTTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTC
ATCCGCAAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTG
TCCTGGTACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATG
TCGAGCAAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAG
GAGGAGGTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAG
GAGAATGGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATG
GCCATTGTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAG
CTGCTGGCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGC
ATGTACCACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGAC
TCCTGGCTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCA
GCCCGGCCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGG
GCTTCCCCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGCCGATCGGGTCAGGCA
AGTCCATCCCGTCCTGAGAGCCCCAGGCCCCCCTTCGACCTCTAAACAGATCCCTCCTCTTCTCGGAGACCTCCCTTTCCAAGCCTGCCT
GGACGGCTGTTCTGTGACTTGACAGTGGCTCCCCCAGCCCCAAAGCCAGCCCCCTTCATCTGTGACTTAATCTGTTGTAGTGGTGAGCTG
ATACATTCAGGTGTGACCGTTGGTGAAAACTTGTGCCCCTTCTGTGGTATGCCCTTGCCCTGTTCTATAAATATCTATAAATACTCATAT
ATATACACACCTACACATGGCCAACCGCCTCGCCTCTAGCGCTGGGAATCAGTCACTGTGCTATCCTTGTGGAGTCTTGTGGCCCAACTA
CCAGAGAACGCTGTCCCCCGACATCCCACTCCAAAGTGTGCCACCTCCAGTGAGCCTCCTTGTCATGCCCGGCCTGTGGACAGCCAGCCC
CCGCCATCCCTCCCACCCCCTACCAAGCATGGGGGTGCTGTGCAGGCAGCCGTGTGGCCTGACAGTTTCTACCAGTCCTGCTGTCCCTCG

>22901_22901_10_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000325385_DNM1_chr9_130996300_ENST00000486160_length(amino acids)=984AA_BP=562
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS
SEVLECLPQGLPWTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQ
KVVPMLPRLLCEELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQA
VLNLHGIAKQLRQQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKK
TSGNQDEILVIRKGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY
RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMI
NNTKEFIFSELLANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT

--------------------------------------------------------------
>22901_22901_11_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996299_ENST00000341179_length(transcript)=3479nt_BP=1659nt
ATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCT
TCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCA
GAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGT
GATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCAT
TGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTC
CCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGC
ATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACA
AAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAG
AAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCC
TCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTG
TTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAG
CCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCA
TGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGAGACCTC
GATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCGGAGGGA
TCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTGTGTGAG
GAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGATGAATGG
TTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATCCCTGCG
AAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAGTTACGC
CAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTGACCACC
CACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCATGAGGAC
TTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTCATCCGC
AAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTGTCCTGG
TACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATGTCGAGC
AAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAGGAGGAG
GTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAGGAGAAT
GGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATGGCCATT
GTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAGCTGCTG
GCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGCATGTAC
CACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGACTCCTGG
CTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCAGCCCGG
CCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGGGCTTCC
CCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGAATCACTATCAGTGACCCCTGA
GGAGCGTCAGCCATGCCGATCGGGTCAGGCAAGTCCATCCCGTCCTGAGAGCCCCAGGCCCCCCTTCGACCTCTAAACAGATCCCTCCTC
TTCTCGGAGACCTCCCTTTCCAAGCCTGCCTGGACGGCTGTTCTGTGACTTGACAGTGGCTCCCCCAGCCCCAAAGCCAGCCCCCTTCAT
CTGTGACTTAATCTGTTGTAGTGGTGAGCTGATACATTCAGGTGTGACCGTTGGTGAAAACTTGTGCCCCTTCTGTGGTATGCCCTTGCC
CTGTTCTATAAATATCTATAAATACTCATATATATACACACCTACACATGGCCAACCGCCTCGCCTCTAGCGCTGGGAATCAGTCACTGT
GCTATCCTTGTGGAGTCTTGTGGCCCAACTACCAGAGAACGCTGTCCCCCGACATCCCACTCCAAAGTGTGCCACCTCCAGTGAGCCTCC
TTGTCATGCCCGGCCTGTGGACAGCCAGCCCCCGCCATCCCTCCCACCCCCTACCAAGCATGGGGGTGCTGTGCAGGCAGCCGTGTGGCC

>22901_22901_11_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996299_ENST00000341179_length(amino acids)=959AA_BP=550
MSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDG
DRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEAQFDGSDSEDGHG
ITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKNSELFRKYALFSP
SDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLP
WTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQKVVPMLPRLLCE
ELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAKQLR
QQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIR
KGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDYRQLELACETQEE
VDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELL
ANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPAR

--------------------------------------------------------------
>22901_22901_12_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996299_ENST00000372923_length(transcript)=3453nt_BP=1659nt
ATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCT
TCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCA
GAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGT
GATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCAT
TGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTC
CCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGC
ATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACA
AAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAG
AAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCC
TCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTG
TTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAG
CCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCA
TGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGAGACCTC
GATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCGGAGGGA
TCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTGTGTGAG
GAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGATGAATGG
TTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATCCCTGCG
AAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAGTTACGC
CAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTGACCACC
CACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCATGAGGAC
TTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTCATCCGC
AAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTGTCCTGG
TACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATGTCGAGC
AAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAGGAGGAG
GTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAGGAGAAT
GGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATGGCCATT
GTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAGCTGCTG
GCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGCATGTAC
CACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGACTCCTGG
CTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCAGCCCGG
CCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGGGCTTCC
CCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGCCGATCGGGTCAGGCAAGTCCA
TCCCGTCCTGAGAGCCCCAGGCCCCCCTTCGACCTCTAAACAGATCCCTCCTCTTCTCGGAGACCTCCCTTTCCAAGCCTGCCTGGACGG
CTGTTCTGTGACTTGACAGTGGCTCCCCCAGCCCCAAAGCCAGCCCCCTTCATCTGTGACTTAATCTGTTGTAGTGGTGAGCTGATACAT
TCAGGTGTGACCGTTGGTGAAAACTTGTGCCCCTTCTGTGGTATGCCCTTGCCCTGTTCTATAAATATCTATAAATACTCATATATATAC
ACACCTACACATGGCCAACCGCCTCGCCTCTAGCGCTGGGAATCAGTCACTGTGCTATCCTTGTGGAGTCTTGTGGCCCAACTACCAGAG
AACGCTGTCCCCCGACATCCCACTCCAAAGTGTGCCACCTCCAGTGAGCCTCCTTGTCATGCCCGGCCTGTGGACAGCCAGCCCCCGCCA
TCCCTCCCACCCCCTACCAAGCATGGGGGTGCTGTGCAGGCAGCCGTGTGGCCTGACAGTTTCTACCAGTCCTGCTGTCCCTCGGCTGAG

>22901_22901_12_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996299_ENST00000372923_length(amino acids)=972AA_BP=550
MSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDG
DRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEAQFDGSDSEDGHG
ITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKNSELFRKYALFSP
SDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLP
WTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQKVVPMLPRLLCE
ELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAKQLR
QQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIR
KGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDYRQLELACETQEE
VDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELL
ANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPAR

--------------------------------------------------------------
>22901_22901_13_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996299_ENST00000393594_length(transcript)=3481nt_BP=1659nt
ATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCT
TCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCA
GAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGT
GATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCAT
TGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTC
CCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGC
ATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACA
AAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAG
AAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCC
TCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTG
TTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAG
CCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCA
TGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGAGACCTC
GATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCGGAGGGA
TCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTGTGTGAG
GAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGATGAATGG
TTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATCCCTGCG
AAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAGTTACGC
CAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTGACCACC
CACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCATGAGGAC
TTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTCATCCGC
AAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTGTCCTGG
TACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATGTCGAGC
AAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAGGAGGAG
GTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAGGAGAAT
GGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATGGCCATT
GTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAGCTGCTG
GCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGCATGTAC
CACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGACTCCTGG
CTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCAGCCCGG
CCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGGGCTTCC
CCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGAATCACTATCAGTGACCCCTGA
GGAGCGTCAGCCATGCCGATCGGGTCAGGCAAGTCCATCCCGTCCTGAGAGCCCCAGGCCCCCCTTCGACCTCTAAACAGATCCCTCCTC
TTCTCGGAGACCTCCCTTTCCAAGCCTGCCTGGACGGCTGTTCTGTGACTTGACAGTGGCTCCCCCAGCCCCAAAGCCAGCCCCCTTCAT
CTGTGACTTAATCTGTTGTAGTGGTGAGCTGATACATTCAGGTGTGACCGTTGGTGAAAACTTGTGCCCCTTCTGTGGTATGCCCTTGCC
CTGTTCTATAAATATCTATAAATACTCATATATATACACACCTACACATGGCCAACCGCCTCGCCTCTAGCGCTGGGAATCAGTCACTGT
GCTATCCTTGTGGAGTCTTGTGGCCCAACTACCAGAGAACGCTGTCCCCCGACATCCCACTCCAAAGTGTGCCACCTCCAGTGAGCCTCC
TTGTCATGCCCGGCCTGTGGACAGCCAGCCCCCGCCATCCCTCCCACCCCCTACCAAGCATGGGGGTGCTGTGCAGGCAGCCGTGTGGCC

>22901_22901_13_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996299_ENST00000393594_length(amino acids)=959AA_BP=550
MSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDG
DRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEAQFDGSDSEDGHG
ITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKNSELFRKYALFSP
SDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLP
WTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQKVVPMLPRLLCE
ELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAKQLR
QQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIR
KGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDYRQLELACETQEE
VDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELL
ANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPAR

--------------------------------------------------------------
>22901_22901_14_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996299_ENST00000475805_length(transcript)=3049nt_BP=1659nt
ATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCT
TCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCA
GAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGT
GATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCAT
TGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTC
CCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGC
ATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACA
AAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAG
AAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCC
TCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTG
TTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAG
CCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCA
TGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGAGACCTC
GATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCGGAGGGA
TCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTGTGTGAG
GAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGATGAATGG
TTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATCCCTGCG
AAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAGTTACGC
CAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTGACCACC
CACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCATGAGGAC
TTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTCATCCGC
AAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTGTCCTGG
TACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATGTCGAGC
AAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAGGAGGAG
GTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAGGAGAAT
GGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATGGCCATT
GTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAGCTGCTG
GCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGCATGTAC
CACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGACTCCTGG
CTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCAGCCCGG
CCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGGGCTTCC
CCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGAATCACTATCAGTGACCCCTGA
GGAGCGTCAGCCATGGAAGGGCCCAGCCTCACCTACGAGACCTGCAGCCCCCCGACCAGCTGAGGCTCCCCTCTTAGACTTATAAGTCTA

>22901_22901_14_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996299_ENST00000475805_length(amino acids)=959AA_BP=550
MSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDG
DRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEAQFDGSDSEDGHG
ITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKNSELFRKYALFSP
SDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLP
WTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQKVVPMLPRLLCE
ELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAKQLR
QQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIR
KGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDYRQLELACETQEE
VDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELL
ANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPAR

--------------------------------------------------------------
>22901_22901_15_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996299_ENST00000486160_length(transcript)=3442nt_BP=1659nt
ATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCT
TCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCA
GAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGT
GATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCAT
TGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTC
CCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGC
ATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACA
AAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAG
AAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCC
TCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTG
TTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAG
CCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCA
TGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGAGACCTC
GATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCGGAGGGA
TCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTGTGTGAG
GAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGATGAATGG
TTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATCCCTGCG
AAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAGTTACGC
CAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTGACCACC
CACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCATGAGGAC
TTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTCATCCGC
AAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTGTCCTGG
TACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATGTCGAGC
AAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAGGAGGAG
GTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAGGAGAAT
GGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATGGCCATT
GTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAGCTGCTG
GCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGCATGTAC
CACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGACTCCTGG
CTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCAGCCCGG
CCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGGGCTTCC
CCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGCCGATCGGGTCAGGCAAGTCCA
TCCCGTCCTGAGAGCCCCAGGCCCCCCTTCGACCTCTAAACAGATCCCTCCTCTTCTCGGAGACCTCCCTTTCCAAGCCTGCCTGGACGG
CTGTTCTGTGACTTGACAGTGGCTCCCCCAGCCCCAAAGCCAGCCCCCTTCATCTGTGACTTAATCTGTTGTAGTGGTGAGCTGATACAT
TCAGGTGTGACCGTTGGTGAAAACTTGTGCCCCTTCTGTGGTATGCCCTTGCCCTGTTCTATAAATATCTATAAATACTCATATATATAC
ACACCTACACATGGCCAACCGCCTCGCCTCTAGCGCTGGGAATCAGTCACTGTGCTATCCTTGTGGAGTCTTGTGGCCCAACTACCAGAG
AACGCTGTCCCCCGACATCCCACTCCAAAGTGTGCCACCTCCAGTGAGCCTCCTTGTCATGCCCGGCCTGTGGACAGCCAGCCCCCGCCA
TCCCTCCCACCCCCTACCAAGCATGGGGGTGCTGTGCAGGCAGCCGTGTGGCCTGACAGTTTCTACCAGTCCTGCTGTCCCTCGGCTGAG

>22901_22901_15_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996299_ENST00000486160_length(amino acids)=972AA_BP=550
MSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDG
DRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEAQFDGSDSEDGHG
ITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKNSELFRKYALFSP
SDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLP
WTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQKVVPMLPRLLCE
ELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAKQLR
QQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIR
KGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDYRQLELACETQEE
VDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELL
ANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPAR

--------------------------------------------------------------
>22901_22901_16_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996300_ENST00000341179_length(transcript)=3479nt_BP=1659nt
ATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCT
TCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCA
GAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGT
GATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCAT
TGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTC
CCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGC
ATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACA
AAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAG
AAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCC
TCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTG
TTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAG
CCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCA
TGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGAGACCTC
GATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCGGAGGGA
TCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTGTGTGAG
GAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGATGAATGG
TTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATCCCTGCG
AAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAGTTACGC
CAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTGACCACC
CACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCATGAGGAC
TTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTCATCCGC
AAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTGTCCTGG
TACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATGTCGAGC
AAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAGGAGGAG
GTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAGGAGAAT
GGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATGGCCATT
GTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAGCTGCTG
GCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGCATGTAC
CACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGACTCCTGG
CTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCAGCCCGG
CCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGGGCTTCC
CCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGAATCACTATCAGTGACCCCTGA
GGAGCGTCAGCCATGCCGATCGGGTCAGGCAAGTCCATCCCGTCCTGAGAGCCCCAGGCCCCCCTTCGACCTCTAAACAGATCCCTCCTC
TTCTCGGAGACCTCCCTTTCCAAGCCTGCCTGGACGGCTGTTCTGTGACTTGACAGTGGCTCCCCCAGCCCCAAAGCCAGCCCCCTTCAT
CTGTGACTTAATCTGTTGTAGTGGTGAGCTGATACATTCAGGTGTGACCGTTGGTGAAAACTTGTGCCCCTTCTGTGGTATGCCCTTGCC
CTGTTCTATAAATATCTATAAATACTCATATATATACACACCTACACATGGCCAACCGCCTCGCCTCTAGCGCTGGGAATCAGTCACTGT
GCTATCCTTGTGGAGTCTTGTGGCCCAACTACCAGAGAACGCTGTCCCCCGACATCCCACTCCAAAGTGTGCCACCTCCAGTGAGCCTCC
TTGTCATGCCCGGCCTGTGGACAGCCAGCCCCCGCCATCCCTCCCACCCCCTACCAAGCATGGGGGTGCTGTGCAGGCAGCCGTGTGGCC

>22901_22901_16_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996300_ENST00000341179_length(amino acids)=959AA_BP=550
MSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDG
DRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEAQFDGSDSEDGHG
ITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKNSELFRKYALFSP
SDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLP
WTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQKVVPMLPRLLCE
ELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAKQLR
QQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIR
KGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDYRQLELACETQEE
VDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELL
ANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPAR

--------------------------------------------------------------
>22901_22901_17_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996300_ENST00000372923_length(transcript)=3453nt_BP=1659nt
ATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCT
TCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCA
GAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGT
GATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCAT
TGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTC
CCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGC
ATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACA
AAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAG
AAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCC
TCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTG
TTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAG
CCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCA
TGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGAGACCTC
GATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCGGAGGGA
TCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTGTGTGAG
GAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGATGAATGG
TTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATCCCTGCG
AAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAGTTACGC
CAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTGACCACC
CACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCATGAGGAC
TTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTCATCCGC
AAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTGTCCTGG
TACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATGTCGAGC
AAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAGGAGGAG
GTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAGGAGAAT
GGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATGGCCATT
GTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAGCTGCTG
GCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGCATGTAC
CACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGACTCCTGG
CTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCAGCCCGG
CCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGGGCTTCC
CCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGCCGATCGGGTCAGGCAAGTCCA
TCCCGTCCTGAGAGCCCCAGGCCCCCCTTCGACCTCTAAACAGATCCCTCCTCTTCTCGGAGACCTCCCTTTCCAAGCCTGCCTGGACGG
CTGTTCTGTGACTTGACAGTGGCTCCCCCAGCCCCAAAGCCAGCCCCCTTCATCTGTGACTTAATCTGTTGTAGTGGTGAGCTGATACAT
TCAGGTGTGACCGTTGGTGAAAACTTGTGCCCCTTCTGTGGTATGCCCTTGCCCTGTTCTATAAATATCTATAAATACTCATATATATAC
ACACCTACACATGGCCAACCGCCTCGCCTCTAGCGCTGGGAATCAGTCACTGTGCTATCCTTGTGGAGTCTTGTGGCCCAACTACCAGAG
AACGCTGTCCCCCGACATCCCACTCCAAAGTGTGCCACCTCCAGTGAGCCTCCTTGTCATGCCCGGCCTGTGGACAGCCAGCCCCCGCCA
TCCCTCCCACCCCCTACCAAGCATGGGGGTGCTGTGCAGGCAGCCGTGTGGCCTGACAGTTTCTACCAGTCCTGCTGTCCCTCGGCTGAG

>22901_22901_17_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996300_ENST00000372923_length(amino acids)=972AA_BP=550
MSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDG
DRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEAQFDGSDSEDGHG
ITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKNSELFRKYALFSP
SDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLP
WTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQKVVPMLPRLLCE
ELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAKQLR
QQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIR
KGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDYRQLELACETQEE
VDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELL
ANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPAR

--------------------------------------------------------------
>22901_22901_18_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996300_ENST00000393594_length(transcript)=3481nt_BP=1659nt
ATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCT
TCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCA
GAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGT
GATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCAT
TGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTC
CCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGC
ATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACA
AAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAG
AAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCC
TCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTG
TTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAG
CCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCA
TGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGAGACCTC
GATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCGGAGGGA
TCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTGTGTGAG
GAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGATGAATGG
TTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATCCCTGCG
AAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAGTTACGC
CAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTGACCACC
CACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCATGAGGAC
TTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTCATCCGC
AAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTGTCCTGG
TACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATGTCGAGC
AAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAGGAGGAG
GTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAGGAGAAT
GGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATGGCCATT
GTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAGCTGCTG
GCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGCATGTAC
CACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGACTCCTGG
CTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCAGCCCGG
CCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGGGCTTCC
CCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGAATCACTATCAGTGACCCCTGA
GGAGCGTCAGCCATGCCGATCGGGTCAGGCAAGTCCATCCCGTCCTGAGAGCCCCAGGCCCCCCTTCGACCTCTAAACAGATCCCTCCTC
TTCTCGGAGACCTCCCTTTCCAAGCCTGCCTGGACGGCTGTTCTGTGACTTGACAGTGGCTCCCCCAGCCCCAAAGCCAGCCCCCTTCAT
CTGTGACTTAATCTGTTGTAGTGGTGAGCTGATACATTCAGGTGTGACCGTTGGTGAAAACTTGTGCCCCTTCTGTGGTATGCCCTTGCC
CTGTTCTATAAATATCTATAAATACTCATATATATACACACCTACACATGGCCAACCGCCTCGCCTCTAGCGCTGGGAATCAGTCACTGT
GCTATCCTTGTGGAGTCTTGTGGCCCAACTACCAGAGAACGCTGTCCCCCGACATCCCACTCCAAAGTGTGCCACCTCCAGTGAGCCTCC
TTGTCATGCCCGGCCTGTGGACAGCCAGCCCCCGCCATCCCTCCCACCCCCTACCAAGCATGGGGGTGCTGTGCAGGCAGCCGTGTGGCC

>22901_22901_18_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996300_ENST00000393594_length(amino acids)=959AA_BP=550
MSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDG
DRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEAQFDGSDSEDGHG
ITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKNSELFRKYALFSP
SDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLP
WTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQKVVPMLPRLLCE
ELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAKQLR
QQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIR
KGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDYRQLELACETQEE
VDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELL
ANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPAR

--------------------------------------------------------------
>22901_22901_19_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996300_ENST00000475805_length(transcript)=3049nt_BP=1659nt
ATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCT
TCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCA
GAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGT
GATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCAT
TGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTC
CCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGC
ATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACA
AAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAG
AAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCC
TCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTG
TTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAG
CCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCA
TGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGAGACCTC
GATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCGGAGGGA
TCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTGTGTGAG
GAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGATGAATGG
TTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATCCCTGCG
AAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAGTTACGC
CAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTGACCACC
CACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCATGAGGAC
TTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTCATCCGC
AAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTGTCCTGG
TACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATGTCGAGC
AAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAGGAGGAG
GTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAGGAGAAT
GGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATGGCCATT
GTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAGCTGCTG
GCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGCATGTAC
CACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGACTCCTGG
CTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCAGCCCGG
CCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGGGCTTCC
CCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGAATCACTATCAGTGACCCCTGA
GGAGCGTCAGCCATGGAAGGGCCCAGCCTCACCTACGAGACCTGCAGCCCCCCGACCAGCTGAGGCTCCCCTCTTAGACTTATAAGTCTA

>22901_22901_19_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996300_ENST00000475805_length(amino acids)=959AA_BP=550
MSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDG
DRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEAQFDGSDSEDGHG
ITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKNSELFRKYALFSP
SDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLP
WTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQKVVPMLPRLLCE
ELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAKQLR
QQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIR
KGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDYRQLELACETQEE
VDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELL
ANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPAR

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>22901_22901_20_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996300_ENST00000486160_length(transcript)=3442nt_BP=1659nt
ATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCT
TCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCA
GAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGT
GATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCAT
TGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTC
CCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGC
ATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACA
AAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAG
AAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCC
TCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTG
TTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAG
CCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCA
TGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGAGACCTC
GATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCGGAGGGA
TCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTGTGTGAG
GAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGATGAATGG
TTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATCCCTGCG
AAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAGTTACGC
CAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTGACCACC
CACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAGGTCATGCTTCTCATCGATATCGAGCTGGCTTACATGAACACCAACCATGAGGAC
TTCATAGGCTTTGCCAATGCTCAGCAGAGGAGCAACCAGATGAACAAGAAGAAGACTTCAGGGAACCAGGATGAGATTCTGGTCATCCGC
AAGGGCTGGCTGACTATCAATAATATTGGCATCATGAAAGGGGGCTCCAAGGAGTACTGGTTTGTGCTGACTGCTGAGAATCTGTCCTGG
TACAAGGATGATGAGGAGAAAGAGAAGAAATACATGCTGTCTGTGGACAACCTCAAGCTGCGGGACGTGGAGAAGGGCTTTATGTCGAGC
AAGCATATCTTTGCCCTCTTTAACACGGAGCAGAGGAATGTCTACAAGGATTATCGGCAGCTGGAGCTAGCCTGTGAGACACAGGAGGAG
GTGGACAGCTGGAAGGCCTCCTTCCTGAGGGCTGGCGTGTACCCTGAGCGTGTTGGGGACAAAGAGAAAGCCAGCGAGACCGAGGAGAAT
GGCTCCGACAGCTTCATGCATTCCATGGACCCACAGCTGGAACGGCAAGTGGAGACCATCCGGAATCTTGTGGACTCATACATGGCCATT
GTCAACAAGACCGTGAGGGACCTCATGCCCAAGACCATCATGCACCTCATGATTAACAATACCAAGGAGTTCATCTTCTCGGAGCTGCTG
GCCAACCTGTACTCGTGTGGGGACCAGAACACGCTGATGGAGGAGTCGGCGGAGCAGGCACAGCGGCGCGACGAGATGCTGCGCATGTAC
CACGCACTGAAGGAGGCGCTCAGCATCATCGGCGACATCAACACGACCACCGTCAGCACGCCCATGCCCCCGCCCGTGGACGACTCCTGG
CTGCAGGTGCAGAGCGTACCGGCCGGACGCAGGTCGCCCACGTCCAGCCCCACGCCGCAGCGCCGAGCCCCCGCCGTGCCCCCAGCCCGG
CCCGGGTCGCGGGGCCCTGCTCCTGGGCCTCCGCCTGCTGGGTCCGCCCTGGGGGGGGCGCCCCCCGTGCCCTCCAGGCCGGGGGCTTCC
CCTGACCCTTTCGGCCCTCCCCCTCAGGTGCCCTCGCGCCCCAACCGCGCCCCGCCCGGGGTCCCCAGCCGATCGGGTCAGGCAAGTCCA
TCCCGTCCTGAGAGCCCCAGGCCCCCCTTCGACCTCTAAACAGATCCCTCCTCTTCTCGGAGACCTCCCTTTCCAAGCCTGCCTGGACGG
CTGTTCTGTGACTTGACAGTGGCTCCCCCAGCCCCAAAGCCAGCCCCCTTCATCTGTGACTTAATCTGTTGTAGTGGTGAGCTGATACAT
TCAGGTGTGACCGTTGGTGAAAACTTGTGCCCCTTCTGTGGTATGCCCTTGCCCTGTTCTATAAATATCTATAAATACTCATATATATAC
ACACCTACACATGGCCAACCGCCTCGCCTCTAGCGCTGGGAATCAGTCACTGTGCTATCCTTGTGGAGTCTTGTGGCCCAACTACCAGAG
AACGCTGTCCCCCGACATCCCACTCCAAAGTGTGCCACCTCCAGTGAGCCTCCTTGTCATGCCCGGCCTGTGGACAGCCAGCCCCCGCCA
TCCCTCCCACCCCCTACCAAGCATGGGGGTGCTGTGCAGGCAGCCGTGTGGCCTGACAGTTTCTACCAGTCCTGCTGTCCCTCGGCTGAG

>22901_22901_20_DIS3L2-DNM1_DIS3L2_chr2_233128150_ENST00000409307_DNM1_chr9_130996300_ENST00000486160_length(amino acids)=972AA_BP=550
MSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDG
DRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEAQFDGSDSEDGHG
ITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKNSELFRKYALFSP
SDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLP
WTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQKVVPMLPRLLCE
ELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAKQLR
QQRFVDGALRLDQLQQYPRLREEMERIVTTHIREREGRTKEQVMLLIDIELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIR
KGWLTINNIGIMKGGSKEYWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDYRQLELACETQEE
VDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVETIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELL
ANLYSCGDQNTLMEESAEQAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPTPQRRAPAVPPAR

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Fusion Gene PPI Analysis for DIS3L2-DNM1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DIS3L2-DNM1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DIS3L2-DNM1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource