FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:DIS3L2-EFHD1 (FusionGDB2 ID:22902)

Fusion Gene Summary for DIS3L2-EFHD1

check button Fusion gene summary
Fusion gene informationFusion gene name: DIS3L2-EFHD1
Fusion gene ID: 22902
HgeneTgene
Gene symbol

DIS3L2

EFHD1

Gene ID

129563

80303

Gene nameDIS3 like 3'-5' exoribonuclease 2EF-hand domain family member D1
SynonymsFAM6A|PRLMNS|hDIS3L2MST133|MSTP133|PP3051|SWS2
Cytomap

2q37.1

2q37.1

Type of geneprotein-codingprotein-coding
DescriptionDIS3-like exonuclease 2DIS3 mitotic control homolog-like 2family with sequence similarity 6, member AEF-hand domain-containing protein D1EF-hand domain-containing protein 1swiprosin-2
Modification date2020031320200313
UniProtAcc

Q8IYB7

Q9BUP0

Ensembl transtripts involved in fusion geneENST00000273009, ENST00000325385, 
ENST00000409307, ENST00000360410, 
ENST00000409401, ENST00000470087, 
ENST00000409708, ENST00000410095, 
ENST00000264059, ENST00000409613, 
Fusion gene scores* DoF score27 X 9 X 12=29165 X 6 X 7=210
# samples 2510
** MAII scorelog2(25/2916*10)=-3.54399071966485
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/210*10)=-1.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DIS3L2 [Title/Abstract] AND EFHD1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDIS3L2(233028342)-EFHD1(233527512), # samples:2
DIS3L2(233075115)-EFHD1(233546295), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneDIS3L2

GO:0010587

miRNA catabolic process

24141620


check buttonFusion gene breakpoints across DIS3L2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EFHD1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PAADTCGA-IB-A6UF-01ADIS3L2chr2

233028342

+EFHD1chr2

233527512

+
ChimerDB4PAADTCGA-IB-A6UFDIS3L2chr2

233028342

+EFHD1chr2

233527512

+
ChimerDB4STADTCGA-D7-A4YU-01ADIS3L2chr2

233075115

+EFHD1chr2

233546295

+
ChimerDB4STADTCGA-D7-A4YUDIS3L2chr2

233075115

+EFHD1chr2

233546294

+


Top

Fusion Gene ORF analysis for DIS3L2-EFHD1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000273009ENST00000409708DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
5CDS-5UTRENST00000273009ENST00000410095DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
5CDS-5UTRENST00000325385ENST00000409708DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
5CDS-5UTRENST00000325385ENST00000410095DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
5CDS-5UTRENST00000409307ENST00000409708DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
5CDS-5UTRENST00000409307ENST00000410095DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
Frame-shiftENST00000273009ENST00000264059DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
Frame-shiftENST00000273009ENST00000264059DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
Frame-shiftENST00000273009ENST00000409613DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
Frame-shiftENST00000273009ENST00000409613DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
Frame-shiftENST00000273009ENST00000410095DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
Frame-shiftENST00000273009ENST00000410095DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
Frame-shiftENST00000325385ENST00000264059DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
Frame-shiftENST00000325385ENST00000264059DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
Frame-shiftENST00000325385ENST00000409613DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
Frame-shiftENST00000325385ENST00000409613DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
Frame-shiftENST00000325385ENST00000410095DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
Frame-shiftENST00000325385ENST00000410095DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
Frame-shiftENST00000409307ENST00000264059DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
Frame-shiftENST00000409307ENST00000264059DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
Frame-shiftENST00000409307ENST00000409613DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
Frame-shiftENST00000409307ENST00000409613DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
Frame-shiftENST00000409307ENST00000410095DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
Frame-shiftENST00000409307ENST00000410095DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
In-frameENST00000273009ENST00000264059DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
In-frameENST00000273009ENST00000409613DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
In-frameENST00000273009ENST00000409708DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
In-frameENST00000273009ENST00000409708DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
In-frameENST00000325385ENST00000264059DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
In-frameENST00000325385ENST00000409613DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
In-frameENST00000325385ENST00000409708DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
In-frameENST00000325385ENST00000409708DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
In-frameENST00000409307ENST00000264059DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
In-frameENST00000409307ENST00000409613DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
In-frameENST00000409307ENST00000409708DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
In-frameENST00000409307ENST00000409708DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
intron-3CDSENST00000360410ENST00000264059DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
intron-3CDSENST00000360410ENST00000264059DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
intron-3CDSENST00000360410ENST00000264059DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
intron-3CDSENST00000360410ENST00000409613DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
intron-3CDSENST00000360410ENST00000409613DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
intron-3CDSENST00000360410ENST00000409613DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
intron-3CDSENST00000360410ENST00000409708DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
intron-3CDSENST00000360410ENST00000409708DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
intron-3CDSENST00000360410ENST00000410095DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
intron-3CDSENST00000360410ENST00000410095DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
intron-3CDSENST00000409401ENST00000264059DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
intron-3CDSENST00000409401ENST00000264059DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
intron-3CDSENST00000409401ENST00000264059DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
intron-3CDSENST00000409401ENST00000409613DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
intron-3CDSENST00000409401ENST00000409613DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
intron-3CDSENST00000409401ENST00000409613DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
intron-3CDSENST00000409401ENST00000409708DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
intron-3CDSENST00000409401ENST00000409708DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
intron-3CDSENST00000409401ENST00000410095DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
intron-3CDSENST00000409401ENST00000410095DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
intron-3CDSENST00000470087ENST00000264059DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
intron-3CDSENST00000470087ENST00000264059DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
intron-3CDSENST00000470087ENST00000264059DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
intron-3CDSENST00000470087ENST00000409613DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
intron-3CDSENST00000470087ENST00000409613DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
intron-3CDSENST00000470087ENST00000409613DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
intron-3CDSENST00000470087ENST00000409708DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
intron-3CDSENST00000470087ENST00000409708DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
intron-3CDSENST00000470087ENST00000410095DIS3L2chr2

233075115

+EFHD1chr2

233546295

+
intron-3CDSENST00000470087ENST00000410095DIS3L2chr2

233075115

+EFHD1chr2

233546294

+
intron-5UTRENST00000360410ENST00000409708DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
intron-5UTRENST00000360410ENST00000410095DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
intron-5UTRENST00000409401ENST00000409708DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
intron-5UTRENST00000409401ENST00000410095DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
intron-5UTRENST00000470087ENST00000409708DIS3L2chr2

233028342

+EFHD1chr2

233527512

+
intron-5UTRENST00000470087ENST00000410095DIS3L2chr2

233028342

+EFHD1chr2

233527512

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000273009DIS3L2chr2233028342+ENST00000409613EFHD1chr2233527512+277717385782155525
ENST00000273009DIS3L2chr2233028342+ENST00000264059EFHD1chr2233527512+321817385782155525
ENST00000325385DIS3L2chr2233028342+ENST00000409613EFHD1chr2233527512+243914002401817525
ENST00000325385DIS3L2chr2233028342+ENST00000264059EFHD1chr2233527512+288014002401817525
ENST00000409307DIS3L2chr2233028342+ENST00000409613EFHD1chr2233527512+2163112401541513
ENST00000409307DIS3L2chr2233028342+ENST00000264059EFHD1chr2233527512+2604112401541513
ENST00000273009DIS3L2chr2233075115+ENST00000409708EFHD1chr2233546295+300818185781843421
ENST00000325385DIS3L2chr2233075115+ENST00000409708EFHD1chr2233546295+267014802401505421
ENST00000409307DIS3L2chr2233075115+ENST00000409708EFHD1chr2233546295+2394120401229409
ENST00000273009DIS3L2chr2233075115+ENST00000409708EFHD1chr2233546294+300818185781843421
ENST00000325385DIS3L2chr2233075115+ENST00000409708EFHD1chr2233546294+267014802401505421
ENST00000409307DIS3L2chr2233075115+ENST00000409708EFHD1chr2233546294+2394120401229409

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000273009ENST00000409613DIS3L2chr2233028342+EFHD1chr2233527512+0.0020303050.9979697
ENST00000273009ENST00000264059DIS3L2chr2233028342+EFHD1chr2233527512+0.0010237020.99897635
ENST00000325385ENST00000409613DIS3L2chr2233028342+EFHD1chr2233527512+0.0017317450.99826825
ENST00000325385ENST00000264059DIS3L2chr2233028342+EFHD1chr2233527512+0.0008558220.9991442
ENST00000409307ENST00000409613DIS3L2chr2233028342+EFHD1chr2233527512+0.0010422980.99895763
ENST00000409307ENST00000264059DIS3L2chr2233028342+EFHD1chr2233527512+0.000535780.9994642
ENST00000273009ENST00000409708DIS3L2chr2233075115+EFHD1chr2233546295+0.0008355960.99916446
ENST00000325385ENST00000409708DIS3L2chr2233075115+EFHD1chr2233546295+0.0006350650.9993649
ENST00000409307ENST00000409708DIS3L2chr2233075115+EFHD1chr2233546295+0.000387140.99961287
ENST00000273009ENST00000409708DIS3L2chr2233075115+EFHD1chr2233546294+0.0008355960.99916446
ENST00000325385ENST00000409708DIS3L2chr2233075115+EFHD1chr2233546294+0.0006350650.9993649
ENST00000409307ENST00000409708DIS3L2chr2233075115+EFHD1chr2233546294+0.000387140.99961287

Top

Fusion Genomic Features for DIS3L2-EFHD1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DIS3L2chr2233075115+EFHD1chr2233546294+2.00E-050.99998
DIS3L2chr2233075115+EFHD1chr2233546294+2.00E-050.99998
DIS3L2chr2233028342+EFHD1chr2233527511+5.71E-141
DIS3L2chr2233028342+EFHD1chr2233527511+5.71E-141
DIS3L2chr2233075115+EFHD1chr2233546294+2.00E-050.99998
DIS3L2chr2233075115+EFHD1chr2233546294+2.00E-050.99998
DIS3L2chr2233028342+EFHD1chr2233527511+5.71E-141
DIS3L2chr2233028342+EFHD1chr2233527511+5.71E-141

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for DIS3L2-EFHD1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:233028342/chr2:233527512)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DIS3L2

Q8IYB7

EFHD1

Q9BUP0

FUNCTION: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation. {ECO:0000255|HAMAP-Rule:MF_03045, ECO:0000269|PubMed:23756462, ECO:0000269|PubMed:24141620}.FUNCTION: Acts as a calcium sensor for mitochondrial flash (mitoflash) activation, an event characterized by stochastic bursts of superoxide production (PubMed:26975899). May play a role in neuronal differentiation (By similarity). {ECO:0000250|UniProtKB:Q9D4J1, ECO:0000269|PubMed:26975899}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneEFHD1chr2:233028342chr2:233527512ENST0000026405904103_114100240.0Calcium binding1
TgeneEFHD1chr2:233028342chr2:233527512ENST0000026405904139_150100240.0Calcium binding2
TgeneEFHD1chr2:233028342chr2:233527512ENST0000040961304103_1144144.0Calcium binding1
TgeneEFHD1chr2:233028342chr2:233527512ENST0000040961304139_1504144.0Calcium binding2
TgeneEFHD1chr2:233075115chr2:233546294ENST0000040961324103_11499144.0Calcium binding1
TgeneEFHD1chr2:233075115chr2:233546294ENST0000040961324139_15099144.0Calcium binding2
TgeneEFHD1chr2:233075115chr2:233546295ENST0000040961324103_11499144.0Calcium binding1
TgeneEFHD1chr2:233075115chr2:233546295ENST0000040961324139_15099144.0Calcium binding2
TgeneEFHD1chr2:233028342chr2:233527512ENST0000026405904126_161100240.0DomainEF-hand 2
TgeneEFHD1chr2:233028342chr2:233527512ENST0000040961304126_1614144.0DomainEF-hand 2
TgeneEFHD1chr2:233028342chr2:233527512ENST000004096130490_1254144.0DomainEF-hand 1
TgeneEFHD1chr2:233075115chr2:233546294ENST0000040961324126_16199144.0DomainEF-hand 2
TgeneEFHD1chr2:233075115chr2:233546295ENST0000040961324126_16199144.0DomainEF-hand 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneEFHD1chr2:233075115chr2:233546294ENST0000026405924103_114195240.0Calcium binding1
TgeneEFHD1chr2:233075115chr2:233546294ENST0000026405924139_150195240.0Calcium binding2
TgeneEFHD1chr2:233075115chr2:233546295ENST0000026405924103_114195240.0Calcium binding1
TgeneEFHD1chr2:233075115chr2:233546295ENST0000026405924139_150195240.0Calcium binding2
TgeneEFHD1chr2:233028342chr2:233527512ENST000002640590490_125100240.0DomainEF-hand 1
TgeneEFHD1chr2:233075115chr2:233546294ENST0000026405924126_161195240.0DomainEF-hand 2
TgeneEFHD1chr2:233075115chr2:233546294ENST000002640592490_125195240.0DomainEF-hand 1
TgeneEFHD1chr2:233075115chr2:233546294ENST000004096132490_12599144.0DomainEF-hand 1
TgeneEFHD1chr2:233075115chr2:233546295ENST0000026405924126_161195240.0DomainEF-hand 2
TgeneEFHD1chr2:233075115chr2:233546295ENST000002640592490_125195240.0DomainEF-hand 1
TgeneEFHD1chr2:233075115chr2:233546295ENST000004096132490_12599144.0DomainEF-hand 1


Top

Fusion Gene Sequence for DIS3L2-EFHD1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>22902_22902_1_DIS3L2-EFHD1_DIS3L2_chr2_233028342_ENST00000273009_EFHD1_chr2_233527512_ENST00000264059_length(transcript)=3218nt_BP=1738nt
ATGCGGGGGTTGTCCATCTCTGTATCCCCAGTGCCAGCACTGCACCTCGCCCCAAGCAGTTGTCCAATAAATGAGCAGTGAGTAAATGAA
AGAATGAGCAAAGCCTTGTAACAGGAAAGGGGCCGGCGGCGTCTGCCGTGCAAGACCTGGCCCAGTGGAGCAGAGCCTGGAGGTTCAGGA
GCCGGGTCTGGAAGGCTCCTTCCGGTGGAAGAGGGGCCCGGAGCCAGCCGGCGCCTGGCACAAGGCGTCTCAGAGGCCGCCCACTGGGAG
CCAACCGTTGCAGCCAGTTGTCCCCGCGAGCGAGGCCGGAGAAGGCGCGGCGGCCCCTGGCCTGGCCATTTCGCCCTTGTCGCAGCTGAA
CCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCACCGTCGCTCTCTAGAACGCCGCG
CCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAAACGCGAATGACAACAGAGCTGC
TCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAGCCAATAATGAGCCATCCTGACT
ACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCTTCGCCAGGTGACAAAA
AGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCAGAAGGCTTGAAGAGAG
GAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGTGATCGAGACATTTTTA
TTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCATTGGAAGGTAGTTAAAC
CAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTCCCGCAACAGTCCCTGA
AAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGCATCACACAAAATGTGC
TGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACAAAAGATGAGACCACCT
GCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAGAAAAAACATTCTCGAG
CAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCCTCAGACCACCGAGTGC
CTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTGTTCATCTGCCGCATTG
TGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAGCCTGAAACAGAAGGAA
TACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCATGGACAATTCCACCAG
AGGAGTTCAGCAAGAGAAGGGATTTAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGC
TGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCC
TGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCC
TGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTCCAAGCCTTGTCATCGGCCAGTAAGTTTGAAGCAGAGTTGAAAGCTG
AGCAAGATGAGCGGAAGCGGGAGGAGGAGGAGAGGCGGCTCCGCCAGGCAGCCTTCCAGAAACTCAAGGCCAACTTCAATACATAGTCCT
GCTGACCTTGCCCTCTGCCCACAGCTGTGCCTCACAGATGCCCCGAGAAGAGATGACTAGGCATCTTCATCACTGCTGTCGGTCCCCTCC
CTGAGCCAGCATCTCCATCCACCACCCCGTGCCAGCTCCCGTGCCAGCCTTCATTCCTCCCAGTGTCCAAGCCCCTCCAGGAGGGTCCTG
GGGTGGGCCAGATGCCTGCCCACCTCTGTCTCCTGCCTCTGCTCCTCTGCCCTTCTTATAGCCAGAACTTGTATCTTCTCAGCAACCTTC
ACTTTGTCCTTGTCCCTTTACCATTCCCCATCAAAGAGTAGTCTGCTATATCAATTTGTGTAGATATGTCTGTCTTTTTGGGTCCTCAGA
GAAAATGCCCATTTTCTCGGAGAATTCTCTGCACTCCTCTCTGCTTCACATTCAACTTCCCTGTTCTCATCTTTGGTAGGATTCTGCCAG
TTGCTTTTGCATCTTCTGTTCCTGGGTAATGGTGGGTCTTAATGGAGGCTGGGTGGACCACTGCCCGTCCACTCTTCAACAGGAGGAACA
GCATGCCACCATAGTAACACACATTAGAGAAAGGACAGAGGTCTGCTCCTTCCTGCCACCTTTCTCCTGGCCCCTTAGCATTCCCCCAGT
CCCTCCCTCTTCACCTTGCTCCGTCTATGTCTTCCCAGCTCAGCCTTTTCCCCACTCTTAAATACTGTACTACTTCACTGTAAGAACGAA
AGAATAGTTAGGATACCAATGAGTAAAAGGGTTCCTGTTCACTCTGACTCTGTGCAAATTGTATTACAGTAGACCGCTGACGTTCCCAAG
TGACAGATCCAGGGCCTTTCAAACATCCCCAAAGTCATGGCCATACTCACCATTAGCCAGTTTCTAACATCTGTTTCAGGGTATCCAGCT
GTAGATGTTCTTATCCCCCATACTTGTGAGTTCTTGGGGTTGCTCACAAATACTAGGGGTTTTTGTTGTATTTTTAACAAATATATCCTA

>22902_22902_1_DIS3L2-EFHD1_DIS3L2_chr2_233028342_ENST00000273009_EFHD1_chr2_233527512_ENST00000264059_length(amino acids)=525AA_BP=1
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS
SEVLECLPQGLPWTIPPEEFSKRRDLRYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKSMIKEVDEDFDGKLSFREFLLIFHKAAAGELQ

--------------------------------------------------------------
>22902_22902_2_DIS3L2-EFHD1_DIS3L2_chr2_233028342_ENST00000273009_EFHD1_chr2_233527512_ENST00000409613_length(transcript)=2777nt_BP=1738nt
ATGCGGGGGTTGTCCATCTCTGTATCCCCAGTGCCAGCACTGCACCTCGCCCCAAGCAGTTGTCCAATAAATGAGCAGTGAGTAAATGAA
AGAATGAGCAAAGCCTTGTAACAGGAAAGGGGCCGGCGGCGTCTGCCGTGCAAGACCTGGCCCAGTGGAGCAGAGCCTGGAGGTTCAGGA
GCCGGGTCTGGAAGGCTCCTTCCGGTGGAAGAGGGGCCCGGAGCCAGCCGGCGCCTGGCACAAGGCGTCTCAGAGGCCGCCCACTGGGAG
CCAACCGTTGCAGCCAGTTGTCCCCGCGAGCGAGGCCGGAGAAGGCGCGGCGGCCCCTGGCCTGGCCATTTCGCCCTTGTCGCAGCTGAA
CCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCACCGTCGCTCTCTAGAACGCCGCG
CCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAAACGCGAATGACAACAGAGCTGC
TCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAGCCAATAATGAGCCATCCTGACT
ACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCTTCGCCAGGTGACAAAA
AGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCAGAAGGCTTGAAGAGAG
GAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGTGATCGAGACATTTTTA
TTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCATTGGAAGGTAGTTAAAC
CAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTCCCGCAACAGTCCCTGA
AAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGCATCACACAAAATGTGC
TGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACAAAAGATGAGACCACCT
GCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAGAAAAAACATTCTCGAG
CAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCCTCAGACCACCGAGTGC
CTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTGTTCATCTGCCGCATTG
TGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAGCCTGAAACAGAAGGAA
TACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCATGGACAATTCCACCAG
AGGAGTTCAGCAAGAGAAGGGATTTAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAGCTGATGATGGAGAAGC
TGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTCAGCTTCCGGGAGTTCC
TGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCTGAGATCGATGTGGCCC
TGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTCCAAGCCTTGTCATCGGCCAGTAAGTTTGAAGCAGAGTTGAAAGCTG
AGCAAGATGAGCGGAAGCGGGAGGAGGAGGAGAGGCGGCTCCGCCAGGCAGCCTTCCAGAAACTCAAGGCCAACTTCAATACATAGTCCT
GCTGACCTTGCCCTCTGCCCACAGCTGTGCCTCACAGATGCCCCGAGAAGAGATGACTAGGCATCTTCATCACTGCTGTCGGTCCCCTCC
CTGAGCCAGCATCTCCATCCACCACCCCGTGCCAGCTCCCGTGCCAGCCTTCATTCCTCCCAGTGTCCAAGCCCCTCCAGGAGGGTCCTG
GGGTGGGCCAGATGCCTGCCCACCTCTGTCTCCTGCCTCTGCTCCTCTGCCCTTCTTATAGCCAGAACTTGTATCTTCTCAGCAACCTTC
ACTTTGTCCTTGTCCCTTTACCATTCCCCATCAAAGAGTAGTCTGCTATATCAATTTGTGTAGATATGTCTGTCTTTTTGGGTCCTCAGA
GAAAATGCCCATTTTCTCGGAGAATTCTCTGCACTCCTCTCTGCTTCACATTCAACTTCCCTGTTCTCATCTTTGGTAGGATTCTGCCAG
TTGCTTTTGCATCTTCTGTTCCTGGGTAATGGTGGGTCTTAATGGAGGCTGGGTGGACCACTGCCCGTCCACTCTTCAACAGGAGGAACA

>22902_22902_2_DIS3L2-EFHD1_DIS3L2_chr2_233028342_ENST00000273009_EFHD1_chr2_233527512_ENST00000409613_length(amino acids)=525AA_BP=1
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS
SEVLECLPQGLPWTIPPEEFSKRRDLRYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKSMIKEVDEDFDGKLSFREFLLIFHKAAAGELQ

--------------------------------------------------------------
>22902_22902_3_DIS3L2-EFHD1_DIS3L2_chr2_233028342_ENST00000325385_EFHD1_chr2_233527512_ENST00000264059_length(transcript)=2880nt_BP=1400nt
TTTCGCCCTTGTCGCAGCTGAACCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCAC
CGTCGCTCTCTAGAACGCCGCGCCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAA
ACGCGAATGACAACAGAGCTGCTCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAG
CCAATAATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATT
GGTGCTTCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGAT
GTTTCAGAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCG
GATGGTGATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAG
GAGCATTGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACAC
CATCTCCCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGA
CATGGCATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCG
GTTACAAAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATC
TTGGAGAAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTT
TCTCCCTCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAAC
ACACTGTTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAA
ATTGAGCCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGC
CTGCCATGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAG
CTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGC
AAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAG
CTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTCCAAGCCTTGTCATCGGCCAGTAAG
TTTGAAGCAGAGTTGAAAGCTGAGCAAGATGAGCGGAAGCGGGAGGAGGAGGAGAGGCGGCTCCGCCAGGCAGCCTTCCAGAAACTCAAG
GCCAACTTCAATACATAGTCCTGCTGACCTTGCCCTCTGCCCACAGCTGTGCCTCACAGATGCCCCGAGAAGAGATGACTAGGCATCTTC
ATCACTGCTGTCGGTCCCCTCCCTGAGCCAGCATCTCCATCCACCACCCCGTGCCAGCTCCCGTGCCAGCCTTCATTCCTCCCAGTGTCC
AAGCCCCTCCAGGAGGGTCCTGGGGTGGGCCAGATGCCTGCCCACCTCTGTCTCCTGCCTCTGCTCCTCTGCCCTTCTTATAGCCAGAAC
TTGTATCTTCTCAGCAACCTTCACTTTGTCCTTGTCCCTTTACCATTCCCCATCAAAGAGTAGTCTGCTATATCAATTTGTGTAGATATG
TCTGTCTTTTTGGGTCCTCAGAGAAAATGCCCATTTTCTCGGAGAATTCTCTGCACTCCTCTCTGCTTCACATTCAACTTCCCTGTTCTC
ATCTTTGGTAGGATTCTGCCAGTTGCTTTTGCATCTTCTGTTCCTGGGTAATGGTGGGTCTTAATGGAGGCTGGGTGGACCACTGCCCGT
CCACTCTTCAACAGGAGGAACAGCATGCCACCATAGTAACACACATTAGAGAAAGGACAGAGGTCTGCTCCTTCCTGCCACCTTTCTCCT
GGCCCCTTAGCATTCCCCCAGTCCCTCCCTCTTCACCTTGCTCCGTCTATGTCTTCCCAGCTCAGCCTTTTCCCCACTCTTAAATACTGT
ACTACTTCACTGTAAGAACGAAAGAATAGTTAGGATACCAATGAGTAAAAGGGTTCCTGTTCACTCTGACTCTGTGCAAATTGTATTACA
GTAGACCGCTGACGTTCCCAAGTGACAGATCCAGGGCCTTTCAAACATCCCCAAAGTCATGGCCATACTCACCATTAGCCAGTTTCTAAC
ATCTGTTTCAGGGTATCCAGCTGTAGATGTTCTTATCCCCCATACTTGTGAGTTCTTGGGGTTGCTCACAAATACTAGGGGTTTTTGTTG
TATTTTTAACAAATATATCCTAATGTCATATTTATTCTCTTTTGTAACTGCTGTCTTTACAATAAAGAAATCATCTGCCTTTCTATCTTA

>22902_22902_3_DIS3L2-EFHD1_DIS3L2_chr2_233028342_ENST00000325385_EFHD1_chr2_233527512_ENST00000264059_length(amino acids)=525AA_BP=1
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS
SEVLECLPQGLPWTIPPEEFSKRRDLRYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKSMIKEVDEDFDGKLSFREFLLIFHKAAAGELQ

--------------------------------------------------------------
>22902_22902_4_DIS3L2-EFHD1_DIS3L2_chr2_233028342_ENST00000325385_EFHD1_chr2_233527512_ENST00000409613_length(transcript)=2439nt_BP=1400nt
TTTCGCCCTTGTCGCAGCTGAACCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCAC
CGTCGCTCTCTAGAACGCCGCGCCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAA
ACGCGAATGACAACAGAGCTGCTCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAG
CCAATAATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATT
GGTGCTTCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGAT
GTTTCAGAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCG
GATGGTGATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAG
GAGCATTGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACAC
CATCTCCCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGA
CATGGCATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCG
GTTACAAAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATC
TTGGAGAAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTT
TCTCCCTCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAAC
ACACTGTTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAA
ATTGAGCCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGC
CTGCCATGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAG
CTGAAGCTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGC
AAGCTCAGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAG
CTTTCTGAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTCCAAGCCTTGTCATCGGCCAGTAAG
TTTGAAGCAGAGTTGAAAGCTGAGCAAGATGAGCGGAAGCGGGAGGAGGAGGAGAGGCGGCTCCGCCAGGCAGCCTTCCAGAAACTCAAG
GCCAACTTCAATACATAGTCCTGCTGACCTTGCCCTCTGCCCACAGCTGTGCCTCACAGATGCCCCGAGAAGAGATGACTAGGCATCTTC
ATCACTGCTGTCGGTCCCCTCCCTGAGCCAGCATCTCCATCCACCACCCCGTGCCAGCTCCCGTGCCAGCCTTCATTCCTCCCAGTGTCC
AAGCCCCTCCAGGAGGGTCCTGGGGTGGGCCAGATGCCTGCCCACCTCTGTCTCCTGCCTCTGCTCCTCTGCCCTTCTTATAGCCAGAAC
TTGTATCTTCTCAGCAACCTTCACTTTGTCCTTGTCCCTTTACCATTCCCCATCAAAGAGTAGTCTGCTATATCAATTTGTGTAGATATG
TCTGTCTTTTTGGGTCCTCAGAGAAAATGCCCATTTTCTCGGAGAATTCTCTGCACTCCTCTCTGCTTCACATTCAACTTCCCTGTTCTC
ATCTTTGGTAGGATTCTGCCAGTTGCTTTTGCATCTTCTGTTCCTGGGTAATGGTGGGTCTTAATGGAGGCTGGGTGGACCACTGCCCGT
CCACTCTTCAACAGGAGGAACAGCATGCCACCATAGTAACACACATTAGAGAAAGGACAGAGGTCTGCTCCTTCCTGCCACCTTTCTCCT

>22902_22902_4_DIS3L2-EFHD1_DIS3L2_chr2_233028342_ENST00000325385_EFHD1_chr2_233527512_ENST00000409613_length(amino acids)=525AA_BP=1
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS
SEVLECLPQGLPWTIPPEEFSKRRDLRYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKSMIKEVDEDFDGKLSFREFLLIFHKAAAGELQ

--------------------------------------------------------------
>22902_22902_5_DIS3L2-EFHD1_DIS3L2_chr2_233028342_ENST00000409307_EFHD1_chr2_233527512_ENST00000264059_length(transcript)=2604nt_BP=1124nt
ATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCT
TCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCA
GAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGT
GATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCAT
TGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTC
CCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGC
ATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACA
AAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAG
AAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCC
TCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTG
TTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAG
CCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCA
TGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAG
CTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTC
AGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCT
GAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTCCAAGCCTTGTCATCGGCCAGTAAGTTTGAA
GCAGAGTTGAAAGCTGAGCAAGATGAGCGGAAGCGGGAGGAGGAGGAGAGGCGGCTCCGCCAGGCAGCCTTCCAGAAACTCAAGGCCAAC
TTCAATACATAGTCCTGCTGACCTTGCCCTCTGCCCACAGCTGTGCCTCACAGATGCCCCGAGAAGAGATGACTAGGCATCTTCATCACT
GCTGTCGGTCCCCTCCCTGAGCCAGCATCTCCATCCACCACCCCGTGCCAGCTCCCGTGCCAGCCTTCATTCCTCCCAGTGTCCAAGCCC
CTCCAGGAGGGTCCTGGGGTGGGCCAGATGCCTGCCCACCTCTGTCTCCTGCCTCTGCTCCTCTGCCCTTCTTATAGCCAGAACTTGTAT
CTTCTCAGCAACCTTCACTTTGTCCTTGTCCCTTTACCATTCCCCATCAAAGAGTAGTCTGCTATATCAATTTGTGTAGATATGTCTGTC
TTTTTGGGTCCTCAGAGAAAATGCCCATTTTCTCGGAGAATTCTCTGCACTCCTCTCTGCTTCACATTCAACTTCCCTGTTCTCATCTTT
GGTAGGATTCTGCCAGTTGCTTTTGCATCTTCTGTTCCTGGGTAATGGTGGGTCTTAATGGAGGCTGGGTGGACCACTGCCCGTCCACTC
TTCAACAGGAGGAACAGCATGCCACCATAGTAACACACATTAGAGAAAGGACAGAGGTCTGCTCCTTCCTGCCACCTTTCTCCTGGCCCC
TTAGCATTCCCCCAGTCCCTCCCTCTTCACCTTGCTCCGTCTATGTCTTCCCAGCTCAGCCTTTTCCCCACTCTTAAATACTGTACTACT
TCACTGTAAGAACGAAAGAATAGTTAGGATACCAATGAGTAAAAGGGTTCCTGTTCACTCTGACTCTGTGCAAATTGTATTACAGTAGAC
CGCTGACGTTCCCAAGTGACAGATCCAGGGCCTTTCAAACATCCCCAAAGTCATGGCCATACTCACCATTAGCCAGTTTCTAACATCTGT
TTCAGGGTATCCAGCTGTAGATGTTCTTATCCCCCATACTTGTGAGTTCTTGGGGTTGCTCACAAATACTAGGGGTTTTTGTTGTATTTT

>22902_22902_5_DIS3L2-EFHD1_DIS3L2_chr2_233028342_ENST00000409307_EFHD1_chr2_233527512_ENST00000264059_length(amino acids)=513AA_BP=0
MSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDG
DRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEAQFDGSDSEDGHG
ITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKNSELFRKYALFSP
SDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLP
WTIPPEEFSKRRDLRYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKSMIKEVDEDFDGKLSFREFLLIFHKAAAGELQEDSGLMALAKLS

--------------------------------------------------------------
>22902_22902_6_DIS3L2-EFHD1_DIS3L2_chr2_233028342_ENST00000409307_EFHD1_chr2_233527512_ENST00000409613_length(transcript)=2163nt_BP=1124nt
ATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCT
TCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCA
GAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGT
GATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCAT
TGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTC
CCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGC
ATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACA
AAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAG
AAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCC
TCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTG
TTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAG
CCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCA
TGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGGTATGACGCTGGGCGGGATGGCTTCATCGACCTGATGGAGCTGAAG
CTGATGATGGAGAAGCTGGGGGCCCCCCAGACCCACCTGGGCCTGAAGAGCATGATCAAGGAGGTGGATGAGGACTTCGATGGCAAGCTC
AGCTTCCGGGAGTTCCTGCTCATTTTCCACAAGGCCGCGGCAGGGGAGCTGCAGGAGGACAGTGGGCTGATGGCGCTGGCAAAGCTTTCT
GAGATCGATGTGGCCCTGGAGGGTGTCAAAGGTGCCAAGAACTTCTTTGAAGCCAAGGTCCAAGCCTTGTCATCGGCCAGTAAGTTTGAA
GCAGAGTTGAAAGCTGAGCAAGATGAGCGGAAGCGGGAGGAGGAGGAGAGGCGGCTCCGCCAGGCAGCCTTCCAGAAACTCAAGGCCAAC
TTCAATACATAGTCCTGCTGACCTTGCCCTCTGCCCACAGCTGTGCCTCACAGATGCCCCGAGAAGAGATGACTAGGCATCTTCATCACT
GCTGTCGGTCCCCTCCCTGAGCCAGCATCTCCATCCACCACCCCGTGCCAGCTCCCGTGCCAGCCTTCATTCCTCCCAGTGTCCAAGCCC
CTCCAGGAGGGTCCTGGGGTGGGCCAGATGCCTGCCCACCTCTGTCTCCTGCCTCTGCTCCTCTGCCCTTCTTATAGCCAGAACTTGTAT
CTTCTCAGCAACCTTCACTTTGTCCTTGTCCCTTTACCATTCCCCATCAAAGAGTAGTCTGCTATATCAATTTGTGTAGATATGTCTGTC
TTTTTGGGTCCTCAGAGAAAATGCCCATTTTCTCGGAGAATTCTCTGCACTCCTCTCTGCTTCACATTCAACTTCCCTGTTCTCATCTTT
GGTAGGATTCTGCCAGTTGCTTTTGCATCTTCTGTTCCTGGGTAATGGTGGGTCTTAATGGAGGCTGGGTGGACCACTGCCCGTCCACTC
TTCAACAGGAGGAACAGCATGCCACCATAGTAACACACATTAGAGAAAGGACAGAGGTCTGCTCCTTCCTGCCACCTTTCTCCTGGCCCC

>22902_22902_6_DIS3L2-EFHD1_DIS3L2_chr2_233028342_ENST00000409307_EFHD1_chr2_233527512_ENST00000409613_length(amino acids)=513AA_BP=0
MSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDG
DRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEAQFDGSDSEDGHG
ITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKNSELFRKYALFSP
SDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLP
WTIPPEEFSKRRDLRYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKSMIKEVDEDFDGKLSFREFLLIFHKAAAGELQEDSGLMALAKLS

--------------------------------------------------------------
>22902_22902_7_DIS3L2-EFHD1_DIS3L2_chr2_233075115_ENST00000273009_EFHD1_chr2_233546294_ENST00000409708_length(transcript)=3008nt_BP=1818nt
ATGCGGGGGTTGTCCATCTCTGTATCCCCAGTGCCAGCACTGCACCTCGCCCCAAGCAGTTGTCCAATAAATGAGCAGTGAGTAAATGAA
AGAATGAGCAAAGCCTTGTAACAGGAAAGGGGCCGGCGGCGTCTGCCGTGCAAGACCTGGCCCAGTGGAGCAGAGCCTGGAGGTTCAGGA
GCCGGGTCTGGAAGGCTCCTTCCGGTGGAAGAGGGGCCCGGAGCCAGCCGGCGCCTGGCACAAGGCGTCTCAGAGGCCGCCCACTGGGAG
CCAACCGTTGCAGCCAGTTGTCCCCGCGAGCGAGGCCGGAGAAGGCGCGGCGGCCCCTGGCCTGGCCATTTCGCCCTTGTCGCAGCTGAA
CCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCACCGTCGCTCTCTAGAACGCCGCG
CCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAAACGCGAATGACAACAGAGCTGC
TCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAGCCAATAATGAGCCATCCTGACT
ACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCTTCGCCAGGTGACAAAA
AGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCAGAAGGCTTGAAGAGAG
GAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGTGATCGAGACATTTTTA
TTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCATTGGAAGGTAGTTAAAC
CAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTCCCGCAACAGTCCCTGA
AAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGCATCACACAAAATGTGC
TGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACAAAAGATGAGACCACCT
GCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAGAAAAAACATTCTCGAG
CAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCCTCAGACCACCGAGTGC
CTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTGTTCATCTGCCGCATTG
TGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAGCCTGAAACAGAAGGAA
TACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCATGGACAATTCCACCAG
AGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGAGACCTCGATGATGCCCTCTCCT
GCAAGCCACTCGCTGACGGTCCAAGCCTTGTCATCGGCCAGTAAGTTTGAAGCAGAGTTGAAAGCTGAGCAAGATGAGCGGAAGCGGGAG
GAGGAGGAGAGGCGGCTCCGCCAGGCAGCCTTCCAGAAACTCAAGGCCAACTTCAATACATAGTCCTGCTGACCTTGCCCTCTGCCCACA
GCTGTGCCTCACAGATGCCCCGAGAAGAGATGACTAGGCATCTTCATCACTGCTGTCGGTCCCCTCCCTGAGCCAGCATCTCCATCCACC
ACCCCGTGCCAGCTCCCGTGCCAGCCTTCATTCCTCCCAGTGTCCAAGCCCCTCCAGGAGGGTCCTGGGGTGGGCCAGATGCCTGCCCAC
CTCTGTCTCCTGCCTCTGCTCCTCTGCCCTTCTTATAGCCAGAACTTGTATCTTCTCAGCAACCTTCACTTTGTCCTTGTCCCTTTACCA
TTCCCCATCAAAGAGTAGTCTGCTATATCAATTTGTGTAGATATGTCTGTCTTTTTGGGTCCTCAGAGAAAATGCCCATTTTCTCGGAGA
ATTCTCTGCACTCCTCTCTGCTTCACATTCAACTTCCCTGTTCTCATCTTTGGTAGGATTCTGCCAGTTGCTTTTGCATCTTCTGTTCCT
GGGTAATGGTGGGTCTTAATGGAGGCTGGGTGGACCACTGCCCGTCCACTCTTCAACAGGAGGAACAGCATGCCACCATAGTAACACACA
TTAGAGAAAGGACAGAGGTCTGCTCCTTCCTGCCACCTTTCTCCTGGCCCCTTAGCATTCCCCCAGTCCCTCCCTCTTCACCTTGCTCCG
TCTATGTCTTCCCAGCTCAGCCTTTTCCCCACTCTTAAATACTGTACTACTTCACTGTAAGAACGAAAGAATAGTTAGGATACCAATGAG
TAAAAGGGTTCCTGTTCACTCTGACTCTGTGCAAATTGTATTACAGTAGACCGCTGACGTTCCCAAGTGACAGATCCAGGGCCTTTCAAA
CATCCCCAAAGTCATGGCCATACTCACCATTAGCCAGTTTCTAACATCTGTTTCAGGGTATCCAGCTGTAGATGTTCTTATCCCCCATAC
TTGTGAGTTCTTGGGGTTGCTCACAAATACTAGGGGTTTTTGTTGTATTTTTAACAAATATATCCTAATGTCATATTTATTCTCTTTTGT

>22902_22902_7_DIS3L2-EFHD1_DIS3L2_chr2_233075115_ENST00000273009_EFHD1_chr2_233546294_ENST00000409708_length(amino acids)=421AA_BP=
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS

--------------------------------------------------------------
>22902_22902_8_DIS3L2-EFHD1_DIS3L2_chr2_233075115_ENST00000273009_EFHD1_chr2_233546295_ENST00000409708_length(transcript)=3008nt_BP=1818nt
ATGCGGGGGTTGTCCATCTCTGTATCCCCAGTGCCAGCACTGCACCTCGCCCCAAGCAGTTGTCCAATAAATGAGCAGTGAGTAAATGAA
AGAATGAGCAAAGCCTTGTAACAGGAAAGGGGCCGGCGGCGTCTGCCGTGCAAGACCTGGCCCAGTGGAGCAGAGCCTGGAGGTTCAGGA
GCCGGGTCTGGAAGGCTCCTTCCGGTGGAAGAGGGGCCCGGAGCCAGCCGGCGCCTGGCACAAGGCGTCTCAGAGGCCGCCCACTGGGAG
CCAACCGTTGCAGCCAGTTGTCCCCGCGAGCGAGGCCGGAGAAGGCGCGGCGGCCCCTGGCCTGGCCATTTCGCCCTTGTCGCAGCTGAA
CCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCACCGTCGCTCTCTAGAACGCCGCG
CCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAAACGCGAATGACAACAGAGCTGC
TCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAGCCAATAATGAGCCATCCTGACT
ACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCTTCGCCAGGTGACAAAA
AGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCAGAAGGCTTGAAGAGAG
GAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGTGATCGAGACATTTTTA
TTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCATTGGAAGGTAGTTAAAC
CAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTCCCGCAACAGTCCCTGA
AAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGCATCACACAAAATGTGC
TGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACAAAAGATGAGACCACCT
GCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAGAAAAAACATTCTCGAG
CAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCCTCAGACCACCGAGTGC
CTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTGTTCATCTGCCGCATTG
TGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAGCCTGAAACAGAAGGAA
TACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCATGGACAATTCCACCAG
AGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGAGACCTCGATGATGCCCTCTCCT
GCAAGCCACTCGCTGACGGTCCAAGCCTTGTCATCGGCCAGTAAGTTTGAAGCAGAGTTGAAAGCTGAGCAAGATGAGCGGAAGCGGGAG
GAGGAGGAGAGGCGGCTCCGCCAGGCAGCCTTCCAGAAACTCAAGGCCAACTTCAATACATAGTCCTGCTGACCTTGCCCTCTGCCCACA
GCTGTGCCTCACAGATGCCCCGAGAAGAGATGACTAGGCATCTTCATCACTGCTGTCGGTCCCCTCCCTGAGCCAGCATCTCCATCCACC
ACCCCGTGCCAGCTCCCGTGCCAGCCTTCATTCCTCCCAGTGTCCAAGCCCCTCCAGGAGGGTCCTGGGGTGGGCCAGATGCCTGCCCAC
CTCTGTCTCCTGCCTCTGCTCCTCTGCCCTTCTTATAGCCAGAACTTGTATCTTCTCAGCAACCTTCACTTTGTCCTTGTCCCTTTACCA
TTCCCCATCAAAGAGTAGTCTGCTATATCAATTTGTGTAGATATGTCTGTCTTTTTGGGTCCTCAGAGAAAATGCCCATTTTCTCGGAGA
ATTCTCTGCACTCCTCTCTGCTTCACATTCAACTTCCCTGTTCTCATCTTTGGTAGGATTCTGCCAGTTGCTTTTGCATCTTCTGTTCCT
GGGTAATGGTGGGTCTTAATGGAGGCTGGGTGGACCACTGCCCGTCCACTCTTCAACAGGAGGAACAGCATGCCACCATAGTAACACACA
TTAGAGAAAGGACAGAGGTCTGCTCCTTCCTGCCACCTTTCTCCTGGCCCCTTAGCATTCCCCCAGTCCCTCCCTCTTCACCTTGCTCCG
TCTATGTCTTCCCAGCTCAGCCTTTTCCCCACTCTTAAATACTGTACTACTTCACTGTAAGAACGAAAGAATAGTTAGGATACCAATGAG
TAAAAGGGTTCCTGTTCACTCTGACTCTGTGCAAATTGTATTACAGTAGACCGCTGACGTTCCCAAGTGACAGATCCAGGGCCTTTCAAA
CATCCCCAAAGTCATGGCCATACTCACCATTAGCCAGTTTCTAACATCTGTTTCAGGGTATCCAGCTGTAGATGTTCTTATCCCCCATAC
TTGTGAGTTCTTGGGGTTGCTCACAAATACTAGGGGTTTTTGTTGTATTTTTAACAAATATATCCTAATGTCATATTTATTCTCTTTTGT

>22902_22902_8_DIS3L2-EFHD1_DIS3L2_chr2_233075115_ENST00000273009_EFHD1_chr2_233546295_ENST00000409708_length(amino acids)=421AA_BP=
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS

--------------------------------------------------------------
>22902_22902_9_DIS3L2-EFHD1_DIS3L2_chr2_233075115_ENST00000325385_EFHD1_chr2_233546294_ENST00000409708_length(transcript)=2670nt_BP=1480nt
TTTCGCCCTTGTCGCAGCTGAACCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCAC
CGTCGCTCTCTAGAACGCCGCGCCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAA
ACGCGAATGACAACAGAGCTGCTCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAG
CCAATAATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATT
GGTGCTTCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGAT
GTTTCAGAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCG
GATGGTGATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAG
GAGCATTGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACAC
CATCTCCCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGA
CATGGCATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCG
GTTACAAAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATC
TTGGAGAAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTT
TCTCCCTCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAAC
ACACTGTTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAA
ATTGAGCCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGC
CTGCCATGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGA
GACCTCGATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGTCCAAGCCTTGTCATCGGCCAGTAAGTTTGAAGCAGAGTTGAAAGCTGA
GCAAGATGAGCGGAAGCGGGAGGAGGAGGAGAGGCGGCTCCGCCAGGCAGCCTTCCAGAAACTCAAGGCCAACTTCAATACATAGTCCTG
CTGACCTTGCCCTCTGCCCACAGCTGTGCCTCACAGATGCCCCGAGAAGAGATGACTAGGCATCTTCATCACTGCTGTCGGTCCCCTCCC
TGAGCCAGCATCTCCATCCACCACCCCGTGCCAGCTCCCGTGCCAGCCTTCATTCCTCCCAGTGTCCAAGCCCCTCCAGGAGGGTCCTGG
GGTGGGCCAGATGCCTGCCCACCTCTGTCTCCTGCCTCTGCTCCTCTGCCCTTCTTATAGCCAGAACTTGTATCTTCTCAGCAACCTTCA
CTTTGTCCTTGTCCCTTTACCATTCCCCATCAAAGAGTAGTCTGCTATATCAATTTGTGTAGATATGTCTGTCTTTTTGGGTCCTCAGAG
AAAATGCCCATTTTCTCGGAGAATTCTCTGCACTCCTCTCTGCTTCACATTCAACTTCCCTGTTCTCATCTTTGGTAGGATTCTGCCAGT
TGCTTTTGCATCTTCTGTTCCTGGGTAATGGTGGGTCTTAATGGAGGCTGGGTGGACCACTGCCCGTCCACTCTTCAACAGGAGGAACAG
CATGCCACCATAGTAACACACATTAGAGAAAGGACAGAGGTCTGCTCCTTCCTGCCACCTTTCTCCTGGCCCCTTAGCATTCCCCCAGTC
CCTCCCTCTTCACCTTGCTCCGTCTATGTCTTCCCAGCTCAGCCTTTTCCCCACTCTTAAATACTGTACTACTTCACTGTAAGAACGAAA
GAATAGTTAGGATACCAATGAGTAAAAGGGTTCCTGTTCACTCTGACTCTGTGCAAATTGTATTACAGTAGACCGCTGACGTTCCCAAGT
GACAGATCCAGGGCCTTTCAAACATCCCCAAAGTCATGGCCATACTCACCATTAGCCAGTTTCTAACATCTGTTTCAGGGTATCCAGCTG
TAGATGTTCTTATCCCCCATACTTGTGAGTTCTTGGGGTTGCTCACAAATACTAGGGGTTTTTGTTGTATTTTTAACAAATATATCCTAA

>22902_22902_9_DIS3L2-EFHD1_DIS3L2_chr2_233075115_ENST00000325385_EFHD1_chr2_233546294_ENST00000409708_length(amino acids)=421AA_BP=
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS

--------------------------------------------------------------
>22902_22902_10_DIS3L2-EFHD1_DIS3L2_chr2_233075115_ENST00000325385_EFHD1_chr2_233546295_ENST00000409708_length(transcript)=2670nt_BP=1480nt
TTTCGCCCTTGTCGCAGCTGAACCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCAC
CGTCGCTCTCTAGAACGCCGCGCCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAA
ACGCGAATGACAACAGAGCTGCTCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAG
CCAATAATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATT
GGTGCTTCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGAT
GTTTCAGAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCG
GATGGTGATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAG
GAGCATTGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACAC
CATCTCCCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGA
CATGGCATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCG
GTTACAAAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATC
TTGGAGAAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTT
TCTCCCTCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAAC
ACACTGTTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAA
ATTGAGCCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGC
CTGCCATGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGA
GACCTCGATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGTCCAAGCCTTGTCATCGGCCAGTAAGTTTGAAGCAGAGTTGAAAGCTGA
GCAAGATGAGCGGAAGCGGGAGGAGGAGGAGAGGCGGCTCCGCCAGGCAGCCTTCCAGAAACTCAAGGCCAACTTCAATACATAGTCCTG
CTGACCTTGCCCTCTGCCCACAGCTGTGCCTCACAGATGCCCCGAGAAGAGATGACTAGGCATCTTCATCACTGCTGTCGGTCCCCTCCC
TGAGCCAGCATCTCCATCCACCACCCCGTGCCAGCTCCCGTGCCAGCCTTCATTCCTCCCAGTGTCCAAGCCCCTCCAGGAGGGTCCTGG
GGTGGGCCAGATGCCTGCCCACCTCTGTCTCCTGCCTCTGCTCCTCTGCCCTTCTTATAGCCAGAACTTGTATCTTCTCAGCAACCTTCA
CTTTGTCCTTGTCCCTTTACCATTCCCCATCAAAGAGTAGTCTGCTATATCAATTTGTGTAGATATGTCTGTCTTTTTGGGTCCTCAGAG
AAAATGCCCATTTTCTCGGAGAATTCTCTGCACTCCTCTCTGCTTCACATTCAACTTCCCTGTTCTCATCTTTGGTAGGATTCTGCCAGT
TGCTTTTGCATCTTCTGTTCCTGGGTAATGGTGGGTCTTAATGGAGGCTGGGTGGACCACTGCCCGTCCACTCTTCAACAGGAGGAACAG
CATGCCACCATAGTAACACACATTAGAGAAAGGACAGAGGTCTGCTCCTTCCTGCCACCTTTCTCCTGGCCCCTTAGCATTCCCCCAGTC
CCTCCCTCTTCACCTTGCTCCGTCTATGTCTTCCCAGCTCAGCCTTTTCCCCACTCTTAAATACTGTACTACTTCACTGTAAGAACGAAA
GAATAGTTAGGATACCAATGAGTAAAAGGGTTCCTGTTCACTCTGACTCTGTGCAAATTGTATTACAGTAGACCGCTGACGTTCCCAAGT
GACAGATCCAGGGCCTTTCAAACATCCCCAAAGTCATGGCCATACTCACCATTAGCCAGTTTCTAACATCTGTTTCAGGGTATCCAGCTG
TAGATGTTCTTATCCCCCATACTTGTGAGTTCTTGGGGTTGCTCACAAATACTAGGGGTTTTTGTTGTATTTTTAACAAATATATCCTAA

>22902_22902_10_DIS3L2-EFHD1_DIS3L2_chr2_233075115_ENST00000325385_EFHD1_chr2_233546295_ENST00000409708_length(amino acids)=421AA_BP=
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS

--------------------------------------------------------------
>22902_22902_11_DIS3L2-EFHD1_DIS3L2_chr2_233075115_ENST00000409307_EFHD1_chr2_233546294_ENST00000409708_length(transcript)=2394nt_BP=1204nt
ATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCT
TCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCA
GAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGT
GATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCAT
TGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTC
CCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGC
ATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACA
AAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAG
AAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCC
TCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTG
TTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAG
CCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCA
TGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGAGACCTC
GATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGTCCAAGCCTTGTCATCGGCCAGTAAGTTTGAAGCAGAGTTGAAAGCTGAGCAAGA
TGAGCGGAAGCGGGAGGAGGAGGAGAGGCGGCTCCGCCAGGCAGCCTTCCAGAAACTCAAGGCCAACTTCAATACATAGTCCTGCTGACC
TTGCCCTCTGCCCACAGCTGTGCCTCACAGATGCCCCGAGAAGAGATGACTAGGCATCTTCATCACTGCTGTCGGTCCCCTCCCTGAGCC
AGCATCTCCATCCACCACCCCGTGCCAGCTCCCGTGCCAGCCTTCATTCCTCCCAGTGTCCAAGCCCCTCCAGGAGGGTCCTGGGGTGGG
CCAGATGCCTGCCCACCTCTGTCTCCTGCCTCTGCTCCTCTGCCCTTCTTATAGCCAGAACTTGTATCTTCTCAGCAACCTTCACTTTGT
CCTTGTCCCTTTACCATTCCCCATCAAAGAGTAGTCTGCTATATCAATTTGTGTAGATATGTCTGTCTTTTTGGGTCCTCAGAGAAAATG
CCCATTTTCTCGGAGAATTCTCTGCACTCCTCTCTGCTTCACATTCAACTTCCCTGTTCTCATCTTTGGTAGGATTCTGCCAGTTGCTTT
TGCATCTTCTGTTCCTGGGTAATGGTGGGTCTTAATGGAGGCTGGGTGGACCACTGCCCGTCCACTCTTCAACAGGAGGAACAGCATGCC
ACCATAGTAACACACATTAGAGAAAGGACAGAGGTCTGCTCCTTCCTGCCACCTTTCTCCTGGCCCCTTAGCATTCCCCCAGTCCCTCCC
TCTTCACCTTGCTCCGTCTATGTCTTCCCAGCTCAGCCTTTTCCCCACTCTTAAATACTGTACTACTTCACTGTAAGAACGAAAGAATAG
TTAGGATACCAATGAGTAAAAGGGTTCCTGTTCACTCTGACTCTGTGCAAATTGTATTACAGTAGACCGCTGACGTTCCCAAGTGACAGA
TCCAGGGCCTTTCAAACATCCCCAAAGTCATGGCCATACTCACCATTAGCCAGTTTCTAACATCTGTTTCAGGGTATCCAGCTGTAGATG
TTCTTATCCCCCATACTTGTGAGTTCTTGGGGTTGCTCACAAATACTAGGGGTTTTTGTTGTATTTTTAACAAATATATCCTAATGTCAT

>22902_22902_11_DIS3L2-EFHD1_DIS3L2_chr2_233075115_ENST00000409307_EFHD1_chr2_233546294_ENST00000409708_length(amino acids)=409AA_BP=
MSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDG
DRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEAQFDGSDSEDGHG
ITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKNSELFRKYALFSP
SDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLP

--------------------------------------------------------------
>22902_22902_12_DIS3L2-EFHD1_DIS3L2_chr2_233075115_ENST00000409307_EFHD1_chr2_233546295_ENST00000409708_length(transcript)=2394nt_BP=1204nt
ATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCT
TCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCA
GAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGT
GATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCAT
TGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTC
CCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGC
ATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACA
AAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAG
AAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCC
TCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTG
TTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAG
CCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCA
TGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGAGACCTC
GATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGTCCAAGCCTTGTCATCGGCCAGTAAGTTTGAAGCAGAGTTGAAAGCTGAGCAAGA
TGAGCGGAAGCGGGAGGAGGAGGAGAGGCGGCTCCGCCAGGCAGCCTTCCAGAAACTCAAGGCCAACTTCAATACATAGTCCTGCTGACC
TTGCCCTCTGCCCACAGCTGTGCCTCACAGATGCCCCGAGAAGAGATGACTAGGCATCTTCATCACTGCTGTCGGTCCCCTCCCTGAGCC
AGCATCTCCATCCACCACCCCGTGCCAGCTCCCGTGCCAGCCTTCATTCCTCCCAGTGTCCAAGCCCCTCCAGGAGGGTCCTGGGGTGGG
CCAGATGCCTGCCCACCTCTGTCTCCTGCCTCTGCTCCTCTGCCCTTCTTATAGCCAGAACTTGTATCTTCTCAGCAACCTTCACTTTGT
CCTTGTCCCTTTACCATTCCCCATCAAAGAGTAGTCTGCTATATCAATTTGTGTAGATATGTCTGTCTTTTTGGGTCCTCAGAGAAAATG
CCCATTTTCTCGGAGAATTCTCTGCACTCCTCTCTGCTTCACATTCAACTTCCCTGTTCTCATCTTTGGTAGGATTCTGCCAGTTGCTTT
TGCATCTTCTGTTCCTGGGTAATGGTGGGTCTTAATGGAGGCTGGGTGGACCACTGCCCGTCCACTCTTCAACAGGAGGAACAGCATGCC
ACCATAGTAACACACATTAGAGAAAGGACAGAGGTCTGCTCCTTCCTGCCACCTTTCTCCTGGCCCCTTAGCATTCCCCCAGTCCCTCCC
TCTTCACCTTGCTCCGTCTATGTCTTCCCAGCTCAGCCTTTTCCCCACTCTTAAATACTGTACTACTTCACTGTAAGAACGAAAGAATAG
TTAGGATACCAATGAGTAAAAGGGTTCCTGTTCACTCTGACTCTGTGCAAATTGTATTACAGTAGACCGCTGACGTTCCCAAGTGACAGA
TCCAGGGCCTTTCAAACATCCCCAAAGTCATGGCCATACTCACCATTAGCCAGTTTCTAACATCTGTTTCAGGGTATCCAGCTGTAGATG
TTCTTATCCCCCATACTTGTGAGTTCTTGGGGTTGCTCACAAATACTAGGGGTTTTTGTTGTATTTTTAACAAATATATCCTAATGTCAT

>22902_22902_12_DIS3L2-EFHD1_DIS3L2_chr2_233075115_ENST00000409307_EFHD1_chr2_233546295_ENST00000409708_length(amino acids)=409AA_BP=
MSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDG
DRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEAQFDGSDSEDGHG
ITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKNSELFRKYALFSP
SDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLP

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for DIS3L2-EFHD1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for DIS3L2-EFHD1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for DIS3L2-EFHD1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource