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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DIS3L2-NBAS (FusionGDB2 ID:22908)

Fusion Gene Summary for DIS3L2-NBAS

check button Fusion gene summary
Fusion gene informationFusion gene name: DIS3L2-NBAS
Fusion gene ID: 22908
HgeneTgene
Gene symbol

DIS3L2

NBAS

Gene ID

129563

51594

Gene nameDIS3 like 3'-5' exoribonuclease 2NBAS subunit of NRZ tethering complex
SynonymsFAM6A|PRLMNS|hDIS3L2ILFS2|NAG|SOPH
Cytomap

2q37.1

2p24.3

Type of geneprotein-codingprotein-coding
DescriptionDIS3-like exonuclease 2DIS3 mitotic control homolog-like 2family with sequence similarity 6, member Aneuroblastoma-amplified sequenceNAG/BC035112 fusionNAG/FAM49A fusionneuroblastoma amplified sequenceneuroblastoma-amplified gene protein
Modification date2020031320200313
UniProtAcc

Q8IYB7

A2RRP1

Ensembl transtripts involved in fusion geneENST00000325385, ENST00000409307, 
ENST00000273009, ENST00000360410, 
ENST00000409401, ENST00000470087, 
ENST00000281513, ENST00000441750, 
Fusion gene scores* DoF score27 X 9 X 12=291615 X 15 X 6=1350
# samples 2515
** MAII scorelog2(25/2916*10)=-3.54399071966485
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/1350*10)=-3.16992500144231
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DIS3L2 [Title/Abstract] AND NBAS [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDIS3L2(233164829)-NBAS(15523441), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneDIS3L2

GO:0010587

miRNA catabolic process

24141620


check buttonFusion gene breakpoints across DIS3L2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NBAS (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-06-0156-01ADIS3L2chr2

233164829

+NBASchr2

15523441

-


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Fusion Gene ORF analysis for DIS3L2-NBAS

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000325385ENST00000281513DIS3L2chr2

233164829

+NBASchr2

15523441

-
In-frameENST00000325385ENST00000441750DIS3L2chr2

233164829

+NBASchr2

15523441

-
In-frameENST00000409307ENST00000281513DIS3L2chr2

233164829

+NBASchr2

15523441

-
In-frameENST00000409307ENST00000441750DIS3L2chr2

233164829

+NBASchr2

15523441

-
intron-3CDSENST00000273009ENST00000281513DIS3L2chr2

233164829

+NBASchr2

15523441

-
intron-3CDSENST00000273009ENST00000441750DIS3L2chr2

233164829

+NBASchr2

15523441

-
intron-3CDSENST00000360410ENST00000281513DIS3L2chr2

233164829

+NBASchr2

15523441

-
intron-3CDSENST00000360410ENST00000441750DIS3L2chr2

233164829

+NBASchr2

15523441

-
intron-3CDSENST00000409401ENST00000281513DIS3L2chr2

233164829

+NBASchr2

15523441

-
intron-3CDSENST00000409401ENST00000441750DIS3L2chr2

233164829

+NBASchr2

15523441

-
intron-3CDSENST00000470087ENST00000281513DIS3L2chr2

233164829

+NBASchr2

15523441

-
intron-3CDSENST00000470087ENST00000441750DIS3L2chr2

233164829

+NBASchr2

15523441

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000325385DIS3L2chr2233164829+ENST00000441750NBASchr215523441-6014201524058731877
ENST00000325385DIS3L2chr2233164829+ENST00000281513NBASchr215523441-6013201524058731877
ENST00000409307DIS3L2chr2233164829+ENST00000441750NBASchr215523441-57381739055971865
ENST00000409307DIS3L2chr2233164829+ENST00000281513NBASchr215523441-57371739055971865

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000325385ENST00000441750DIS3L2chr2233164829+NBASchr215523441-0.0026938560.9973061
ENST00000325385ENST00000281513DIS3L2chr2233164829+NBASchr215523441-0.0026816180.9973183
ENST00000409307ENST00000441750DIS3L2chr2233164829+NBASchr215523441-0.0018142430.9981857
ENST00000409307ENST00000281513DIS3L2chr2233164829+NBASchr215523441-0.0018073710.9981926

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Fusion Genomic Features for DIS3L2-NBAS


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for DIS3L2-NBAS


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:233164829/chr2:15523441)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DIS3L2

Q8IYB7

NBAS

A2RRP1

FUNCTION: 3'-5'-exoribonuclease that specifically recognizes RNAs polyuridylated at their 3' end and mediates their degradation. Component of an exosome-independent RNA degradation pathway that mediates degradation of both mRNAs and miRNAs that have been polyuridylated by a terminal uridylyltransferase, such as ZCCHC11/TUT4. Mediates degradation of cytoplasmic mRNAs that have been deadenylated and subsequently uridylated at their 3'. Mediates degradation of uridylated pre-let-7 miRNAs, contributing to the maintenance of embryonic stem (ES) cells. Essential for correct mitosis, and negatively regulates cell proliferation. {ECO:0000255|HAMAP-Rule:MF_03045, ECO:0000269|PubMed:23756462, ECO:0000269|PubMed:24141620}.FUNCTION: Involved in Golgi-to-endoplasmic reticulum (ER) retrograde transport; the function is proposed to depend on its association in the NRZ complex which is believed to play a role in SNARE assembly at the ER (PubMed:19369418). {ECO:0000269|PubMed:19369418, ECO:0000305}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneNBASchr2:233164829chr2:15523441ENST0000028151327521421_142510852372.0Compositional biasNote=Poly-Thr
TgeneNBASchr2:233164829chr2:15523441ENST0000028151327522242_224710852372.0Compositional biasNote=Poly-Leu
TgeneNBASchr2:233164829chr2:15523441ENST0000044175025501421_14259652252.0Compositional biasNote=Poly-Thr
TgeneNBASchr2:233164829chr2:15523441ENST0000044175025502242_22479652252.0Compositional biasNote=Poly-Leu

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneNBASchr2:233164829chr2:15523441ENST000002815132752130_16910852372.0RepeatNote=WD 1
TgeneNBASchr2:233164829chr2:15523441ENST000002815132752316_35510852372.0RepeatNote=WD 2
TgeneNBASchr2:233164829chr2:15523441ENST000004417502550130_1699652252.0RepeatNote=WD 1
TgeneNBASchr2:233164829chr2:15523441ENST000004417502550316_3559652252.0RepeatNote=WD 2


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Fusion Gene Sequence for DIS3L2-NBAS


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>22908_22908_1_DIS3L2-NBAS_DIS3L2_chr2_233164829_ENST00000325385_NBAS_chr2_15523441_ENST00000281513_length(transcript)=6013nt_BP=2015nt
TTTCGCCCTTGTCGCAGCTGAACCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCAC
CGTCGCTCTCTAGAACGCCGCGCCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAA
ACGCGAATGACAACAGAGCTGCTCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAG
CCAATAATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATT
GGTGCTTCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGAT
GTTTCAGAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCG
GATGGTGATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAG
GAGCATTGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACAC
CATCTCCCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGA
CATGGCATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCG
GTTACAAAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATC
TTGGAGAAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTT
TCTCCCTCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAAC
ACACTGTTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAA
ATTGAGCCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGC
CTGCCATGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGA
GACCTCGATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCG
GAGGGATCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTG
TGTGAGGAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGAT
GAATGGTTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATC
CCTGCGAAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAG
TTACGCCAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTAAAGCTTGCTTTCACTCTGGACCACGAGACCGGATTGCCTCAA
GGATGTCATATCTATGAGTACCGCGAGAGCAACAAGCAGCCTCCTGTCAGTGAGTCTCATTGGAGAACGTTGCTGCAAGACATGTTAACT
ATGCAGCAGAATGTATACACATGTCTAGATTCTGATGCCTGCTATGAGATATTTACAGAAAGCCTTCTGTGCTCTAGTCGCCTTGAAAAC
ATCCACCTGGCTGGACAGATGATGCACTGCAGTGCTTGTTCAGAAAATCCTCCAGCTGGTATAGCCCATAAAGGGAAACCCCACTACAGG
GTCAGCTACGAAAAGAGTATTGACTTGGTTTTGGCTGCCAGCAGAGAGTACTTCAATTCTTCTACCAACCTCACTGATAGCTGCATGGAT
CTAGCCAGGTGCTGCTTACAACTGATAACAGACAGACCCCCTGCCATTCAAGAGGAGCTAGATCTTATCCAAGCCGTTGGATGTCTTGAA
GAATTTGGGGTAAAGATCCTGCCTTTGCAAGTGCGATTGTGCCCTGATCGGATCAGTCTCATCAAGGAGTGTATTTCCCAGTCCCCCACA
TGCTATAAACAATCCACCAAGCTTCTGGGCCTTGCTGAGCTGCTGAGGGTTGCAGGTGAGAACCCAGAAGAAAGGCGGGGACAGGTTCTA
ATCCTTTTAGTGGAGCAGGCACTTCGCTTCCATGACTACAAAGCAGCCAGTATGCATTGTCAGGAGCTGATGGCCACAGGTTATCCTAAA
AGTTGGGATGTTTGTAGCCAGTTAGGACAATCAGAAGGTTACCAGGACTTGGCCACTCGTCAAGAGCTCATGGCTTTTGCTTTGACACAT
TGCCCTCCTAGCAGCATTGAACTTCTTTTGGCAGCTAGCAGCTCTCTGCAGACAGAAATTCTTTATCAAAGAGTGAATTTCCAGATCCAT
CATGAAGGAGGGGAAAATATCAGTGCTTCACCATTAACTAGTAAAGCAGTACAAGAGGATGAAGTAGGTGTTCCAGGTAGCAATTCAGCT
GACCTATTGCGCTGGACCACTGCTACCACCATGAAAGTCCTTTCCAACACCACAACCACCACCAAAGCGGTGCTGCAGGCCGTCAGTGAT
GGGCAGTGGTGGAAGAAGTCTTTAACTTACCTTCGACCCCTTCAGGGGCAAAAATGTGGTGGTGCATATCAAATCGGAACTACAGCCAAT
GAAGATCTAGAGAAACAAGGGTGTCATCCTTTTTATGAATCTGTCATCTCAAATCCTTTTGTCGCTGAGTCTGAAGGGACCTATGACACC
TATCAGCATGTTCCAGTGGAAAGCTTTGCAGAAGTATTGCTGAGAACTGGAAAATTGGCAGAGGCTAAAAATAAAGGAGAAGTATTTCCA
ACAACTGAAGTTCTCTTGCAACTAGCAAGTGAAGCCTTGCCAAATGACATGACCTTGGCTCTTGCTTACCTTCTTGCCTTACCACAAGTG
TTAGATGCTAACCGGTGCTTTGAAAAGCAGTCCCCCTCTGCATTATCTCTCCAGCTGGCAGCGTATTACTATAGCCTCCAGATCTATGCC
CGATTGGCCCCATGTTTCAGGGACAAGTGCCATCCTCTTTACAGGGCTGATCCCAAAGAACTAATCAAGATGGTCACCAGGCATGTGACT
CGACATGAGCACGAAGCCTGGCCTGAAGACCTTATTTCACTGACCAAGCAGTTACACTGCTACAATGAACGTCTCCTGGATTTCACTCAG
GCGCAGATCCTTCAGGGCCTTCGGAAGGGTGTGGACGTGCAGCGGTTTACTGCAGATGACCAGTATAAAAGGGAAACTATCCTTGGTCTG
GCAGAAACTCTAGAGGAAAGCGTCTACAGCATTGCTATTTCTCTGGCACAACGTTACAGTGTCTCCCGCTGGGAAGTTTTTATGACCCAT
TTGGAGTTCCTCTTCACGGACAGTGGTTTGTCCACACTAGAAATTGAAAATAGAGCCCAAGACCTTCATCTCTTTGAGACTTTGAAGACT
GATCCAGAAGCCTTTCACCAGCACATGGTCAAGTATATTTACCCTACTATTGGTGGCTTTGATCACGAAAGGCTGCAGTATTATTTCACT
CTTCTGGAAAACTGTGGCTGTGCAGATTTGGGGAACTGTGCCATTAAACCAGAAACCCACATTCGACTGCTGAAGAAGTTTAAGGTTGTT
GCATCAGGTCTTAATTACAAAAAGCTGACAGATGAAAACATGAGTCCTCTTGAAGCATTGGAGCCAGTTCTTTCAAGTCAAAATATCTTG
TCTATTTCCAAACTTGTTCCCAAAATCCCTGAAAAGGATGGACAGATGCTTTCCCCAAGCTCTCTGTACACCATCTGGTTACAGAAGTTG
TTCTGGACTGGAGACCCTCATCTCATTAAACAAGTCCCAGGCTCTTCACCGGAGTGGCTTCATGCCTATGATGTCTGCATGAAGTACTTT
GATCGTCTCCACCCAGGTGACCTCATCACTGTGGTAGATGCAGTTACATTTTCTCCAAAAGCTGTGACCAAGCTGTCTGTGGAAGCCCGT
AAAGAGATGACTAGAAAGGCTATTAAGACAGTCAAACATTTTATTGAGAAGCCAAGGAAAAGAAACTCAGAAGACGAAGCTCAAGAAGCT
AAGGATTCTAAAGTTACCTATGCAGATACTTTGAATCATCTGGAGAAATCACTTGCCCACCTGGAAACCCTGAGCCACAGCTTCATCCTT
TCTCTGAAGAATAGTGAGCAGGAAACACTGCAAAAATACAGTCACCTCTATGATCTGTCCCGATCAGAAAAAGAGAAACTTCATGATGAA
GCTGTGGCTATTTGTTTAGATGGTCAGCCTCTAGCAATGATTCAGCAGCTGCTAGAGGTGGCAGTTGGCCCTCTTGACATCTCACCCAAG
GATATAGTGCAGAGTGCAATCATGAAAATAATTTCTGCATTGAGTGGTGGCAGTGCTGACCTTGGTGGGCCAAGGGACCCACTGAAGGTC
CTGGAAGGTGTTGTTGCAGCAGTCCACGCCAGTGTGGACAAGGGTGAGGAGCTGGTTTCACCTGAGGACCTGCTGGAGTGGCTGCGGCCT
TTCTGTGCTGATGACGCCTGGCCGGTGCGGCCCCGCATTCACGTGCTGCAGATTTTGGGGCAATCATTTCACCTGACTGAGGAGGACAGC
AAGCTCCTCGTGTTCTTTAGAACTGAAGCCATTCTCAAAGCCTCCTGGCCCCAGAGACAGGTAGACATAGCTGACATTGAGAATGAAGAG
AACCGCTACTGTCTATTCATGGAACTCCTGGAATCTAGTCACCACGAGGCTGAATTTCAGCACTTGGTTTTACTTTTGCAAGCTTGGCCA
CCTATGAAAAGTGAATATGTCATAACCAATAATCCATGGGTGAGACTAGCTACAGTGATGCTAACCAGATGTACGATGGAGAACAAGGAA
GGATTGGGGAATGAAGTTTTGAAAATGTGTCGCTCTTTGTATAACACCAAGCAGATGCTGCCTGCAGAGGGTGTGAAGGAGCTGTGTCTG
CTGCTGCTTAACCAGTCCCTCCTGCTTCCATCTCTGAAACTTCTCCTCGAGAGCCGAGATGAGCATCTGCACGAGATGGCACTGGAGCAA
ATCACGGCAGTCACTACGGTGAATGATTCCAATTGTGACCAAGAACTTCTTTCCCTGCTCCTGGATGCCAAGCTGCTGGTGAAGTGTGTC
TCCACTCCCTTCTATCCACGTATTGTTGACCACCTCTTGGCTAGCCTCCAGCAAGGGCGCTGGGATGCAGAGGAGCTGGGCAGACACCTG
CGGGAGGCCGGCCATGAAGCCGAAGCCGGGTCTCTCCTTCTGGCCGTGAGGGGGACTCACCAGGCCTTCAGAACCTTCAGTACAGCCCTC
CGCGCAGCACAGCACTGGGTGTGAGGGCCACCTGTGGCCCTGCTCCTTAGCAGAAAAAGCATCTGGAGTTGAATGCTGTTCCCAGAAGCA

>22908_22908_1_DIS3L2-NBAS_DIS3L2_chr2_233164829_ENST00000325385_NBAS_chr2_15523441_ENST00000281513_length(amino acids)=1877AA_BP=592
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS
SEVLECLPQGLPWTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQ
KVVPMLPRLLCEELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQA
VLNLHGIAKQLRQQRFVDGALRLDQLKLAFTLDHETGLPQGCHIYEYRESNKQPPVSESHWRTLLQDMLTMQQNVYTCLDSDACYEIFTE
SLLCSSRLENIHLAGQMMHCSACSENPPAGIAHKGKPHYRVSYEKSIDLVLAASREYFNSSTNLTDSCMDLARCCLQLITDRPPAIQEEL
DLIQAVGCLEEFGVKILPLQVRLCPDRISLIKECISQSPTCYKQSTKLLGLAELLRVAGENPEERRGQVLILLVEQALRFHDYKAASMHC
QELMATGYPKSWDVCSQLGQSEGYQDLATRQELMAFALTHCPPSSIELLLAASSSLQTEILYQRVNFQIHHEGGENISASPLTSKAVQED
EVGVPGSNSADLLRWTTATTMKVLSNTTTTTKAVLQAVSDGQWWKKSLTYLRPLQGQKCGGAYQIGTTANEDLEKQGCHPFYESVISNPF
VAESEGTYDTYQHVPVESFAEVLLRTGKLAEAKNKGEVFPTTEVLLQLASEALPNDMTLALAYLLALPQVLDANRCFEKQSPSALSLQLA
AYYYSLQIYARLAPCFRDKCHPLYRADPKELIKMVTRHVTRHEHEAWPEDLISLTKQLHCYNERLLDFTQAQILQGLRKGVDVQRFTADD
QYKRETILGLAETLEESVYSIAISLAQRYSVSRWEVFMTHLEFLFTDSGLSTLEIENRAQDLHLFETLKTDPEAFHQHMVKYIYPTIGGF
DHERLQYYFTLLENCGCADLGNCAIKPETHIRLLKKFKVVASGLNYKKLTDENMSPLEALEPVLSSQNILSISKLVPKIPEKDGQMLSPS
SLYTIWLQKLFWTGDPHLIKQVPGSSPEWLHAYDVCMKYFDRLHPGDLITVVDAVTFSPKAVTKLSVEARKEMTRKAIKTVKHFIEKPRK
RNSEDEAQEAKDSKVTYADTLNHLEKSLAHLETLSHSFILSLKNSEQETLQKYSHLYDLSRSEKEKLHDEAVAICLDGQPLAMIQQLLEV
AVGPLDISPKDIVQSAIMKIISALSGGSADLGGPRDPLKVLEGVVAAVHASVDKGEELVSPEDLLEWLRPFCADDAWPVRPRIHVLQILG
QSFHLTEEDSKLLVFFRTEAILKASWPQRQVDIADIENEENRYCLFMELLESSHHEAEFQHLVLLLQAWPPMKSEYVITNNPWVRLATVM
LTRCTMENKEGLGNEVLKMCRSLYNTKQMLPAEGVKELCLLLLNQSLLLPSLKLLLESRDEHLHEMALEQITAVTTVNDSNCDQELLSLL

--------------------------------------------------------------
>22908_22908_2_DIS3L2-NBAS_DIS3L2_chr2_233164829_ENST00000325385_NBAS_chr2_15523441_ENST00000441750_length(transcript)=6014nt_BP=2015nt
TTTCGCCCTTGTCGCAGCTGAACCGCCGACTACGAGCTCCTGCACCGCGCACACACCCCGCGCGCTTCGCTCTCGGCCTCGCCCGGCCAC
CGTCGCTCTCTAGAACGCCGCGCCCGTGACCCGGAAGAGCATTCTCCTTAGCAACTGCGGGACTGCGGCGGCGCCGGCCTCCGGGGAGAA
ACGCGAATGACAACAGAGCTGCTCAAGGCGGGAACTCTGAGCTAAGCAGTGGAGGTTTCTCTGGATCTGGAGAGAAGAGTGACCTTGGAG
CCAATAATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATT
GGTGCTTCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGAT
GTTTCAGAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCG
GATGGTGATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAG
GAGCATTGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACAC
CATCTCCCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGA
CATGGCATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCG
GTTACAAAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATC
TTGGAGAAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTT
TCTCCCTCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAAC
ACACTGTTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAA
ATTGAGCCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGC
CTGCCATGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGA
GACCTCGATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCG
GAGGGATCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTG
TGTGAGGAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGAT
GAATGGTTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATC
CCTGCGAAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAG
TTACGCCAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTAAAGCTTGCTTTCACTCTGGACCACGAGACCGGATTGCCTCAA
GGATGTCATATCTATGAGTACCGCGAGAGCAACAAGCAGCCTCCTGTCAGTGAGTCTCATTGGAGAACGTTGCTGCAAGACATGTTAACT
ATGCAGCAGAATGTATACACATGTCTAGATTCTGATGCCTGCTATGAGATATTTACAGAAAGCCTTCTGTGCTCTAGTCGCCTTGAAAAC
ATCCACCTGGCTGGACAGATGATGCACTGCAGTGCTTGTTCAGAAAATCCTCCAGCTGGTATAGCCCATAAAGGGAAACCCCACTACAGG
GTCAGCTACGAAAAGAGTATTGACTTGGTTTTGGCTGCCAGCAGAGAGTACTTCAATTCTTCTACCAACCTCACTGATAGCTGCATGGAT
CTAGCCAGGTGCTGCTTACAACTGATAACAGACAGACCCCCTGCCATTCAAGAGGAGCTAGATCTTATCCAAGCCGTTGGATGTCTTGAA
GAATTTGGGGTAAAGATCCTGCCTTTGCAAGTGCGATTGTGCCCTGATCGGATCAGTCTCATCAAGGAGTGTATTTCCCAGTCCCCCACA
TGCTATAAACAATCCACCAAGCTTCTGGGCCTTGCTGAGCTGCTGAGGGTTGCAGGTGAGAACCCAGAAGAAAGGCGGGGACAGGTTCTA
ATCCTTTTAGTGGAGCAGGCACTTCGCTTCCATGACTACAAAGCAGCCAGTATGCATTGTCAGGAGCTGATGGCCACAGGTTATCCTAAA
AGTTGGGATGTTTGTAGCCAGTTAGGACAATCAGAAGGTTACCAGGACTTGGCCACTCGTCAAGAGCTCATGGCTTTTGCTTTGACACAT
TGCCCTCCTAGCAGCATTGAACTTCTTTTGGCAGCTAGCAGCTCTCTGCAGACAGAAATTCTTTATCAAAGAGTGAATTTCCAGATCCAT
CATGAAGGAGGGGAAAATATCAGTGCTTCACCATTAACTAGTAAAGCAGTACAAGAGGATGAAGTAGGTGTTCCAGGTAGCAATTCAGCT
GACCTATTGCGCTGGACCACTGCTACCACCATGAAAGTCCTTTCCAACACCACAACCACCACCAAAGCGGTGCTGCAGGCCGTCAGTGAT
GGGCAGTGGTGGAAGAAGTCTTTAACTTACCTTCGACCCCTTCAGGGGCAAAAATGTGGTGGTGCATATCAAATCGGAACTACAGCCAAT
GAAGATCTAGAGAAACAAGGGTGTCATCCTTTTTATGAATCTGTCATCTCAAATCCTTTTGTCGCTGAGTCTGAAGGGACCTATGACACC
TATCAGCATGTTCCAGTGGAAAGCTTTGCAGAAGTATTGCTGAGAACTGGAAAATTGGCAGAGGCTAAAAATAAAGGAGAAGTATTTCCA
ACAACTGAAGTTCTCTTGCAACTAGCAAGTGAAGCCTTGCCAAATGACATGACCTTGGCTCTTGCTTACCTTCTTGCCTTACCACAAGTG
TTAGATGCTAACCGGTGCTTTGAAAAGCAGTCCCCCTCTGCATTATCTCTCCAGCTGGCAGCGTATTACTATAGCCTCCAGATCTATGCC
CGATTGGCCCCATGTTTCAGGGACAAGTGCCATCCTCTTTACAGGGCTGATCCCAAAGAACTAATCAAGATGGTCACCAGGCATGTGACT
CGACATGAGCACGAAGCCTGGCCTGAAGACCTTATTTCACTGACCAAGCAGTTACACTGCTACAATGAACGTCTCCTGGATTTCACTCAG
GCGCAGATCCTTCAGGGCCTTCGGAAGGGTGTGGACGTGCAGCGGTTTACTGCAGATGACCAGTATAAAAGGGAAACTATCCTTGGTCTG
GCAGAAACTCTAGAGGAAAGCGTCTACAGCATTGCTATTTCTCTGGCACAACGTTACAGTGTCTCCCGCTGGGAAGTTTTTATGACCCAT
TTGGAGTTCCTCTTCACGGACAGTGGTTTGTCCACACTAGAAATTGAAAATAGAGCCCAAGACCTTCATCTCTTTGAGACTTTGAAGACT
GATCCAGAAGCCTTTCACCAGCACATGGTCAAGTATATTTACCCTACTATTGGTGGCTTTGATCACGAAAGGCTGCAGTATTATTTCACT
CTTCTGGAAAACTGTGGCTGTGCAGATTTGGGGAACTGTGCCATTAAACCAGAAACCCACATTCGACTGCTGAAGAAGTTTAAGGTTGTT
GCATCAGGTCTTAATTACAAAAAGCTGACAGATGAAAACATGAGTCCTCTTGAAGCATTGGAGCCAGTTCTTTCAAGTCAAAATATCTTG
TCTATTTCCAAACTTGTTCCCAAAATCCCTGAAAAGGATGGACAGATGCTTTCCCCAAGCTCTCTGTACACCATCTGGTTACAGAAGTTG
TTCTGGACTGGAGACCCTCATCTCATTAAACAAGTCCCAGGCTCTTCACCGGAGTGGCTTCATGCCTATGATGTCTGCATGAAGTACTTT
GATCGTCTCCACCCAGGTGACCTCATCACTGTGGTAGATGCAGTTACATTTTCTCCAAAAGCTGTGACCAAGCTGTCTGTGGAAGCCCGT
AAAGAGATGACTAGAAAGGCTATTAAGACAGTCAAACATTTTATTGAGAAGCCAAGGAAAAGAAACTCAGAAGACGAAGCTCAAGAAGCT
AAGGATTCTAAAGTTACCTATGCAGATACTTTGAATCATCTGGAGAAATCACTTGCCCACCTGGAAACCCTGAGCCACAGCTTCATCCTT
TCTCTGAAGAATAGTGAGCAGGAAACACTGCAAAAATACAGTCACCTCTATGATCTGTCCCGATCAGAAAAAGAGAAACTTCATGATGAA
GCTGTGGCTATTTGTTTAGATGGTCAGCCTCTAGCAATGATTCAGCAGCTGCTAGAGGTGGCAGTTGGCCCTCTTGACATCTCACCCAAG
GATATAGTGCAGAGTGCAATCATGAAAATAATTTCTGCATTGAGTGGTGGCAGTGCTGACCTTGGTGGGCCAAGGGACCCACTGAAGGTC
CTGGAAGGTGTTGTTGCAGCAGTCCACGCCAGTGTGGACAAGGGTGAGGAGCTGGTTTCACCTGAGGACCTGCTGGAGTGGCTGCGGCCT
TTCTGTGCTGATGACGCCTGGCCGGTGCGGCCCCGCATTCACGTGCTGCAGATTTTGGGGCAATCATTTCACCTGACTGAGGAGGACAGC
AAGCTCCTCGTGTTCTTTAGAACTGAAGCCATTCTCAAAGCCTCCTGGCCCCAGAGACAGGTAGACATAGCTGACATTGAGAATGAAGAG
AACCGCTACTGTCTATTCATGGAACTCCTGGAATCTAGTCACCACGAGGCTGAATTTCAGCACTTGGTTTTACTTTTGCAAGCTTGGCCA
CCTATGAAAAGTGAATATGTCATAACCAATAATCCATGGGTGAGACTAGCTACAGTGATGCTAACCAGATGTACGATGGAGAACAAGGAA
GGATTGGGGAATGAAGTTTTGAAAATGTGTCGCTCTTTGTATAACACCAAGCAGATGCTGCCTGCAGAGGGTGTGAAGGAGCTGTGTCTG
CTGCTGCTTAACCAGTCCCTCCTGCTTCCATCTCTGAAACTTCTCCTCGAGAGCCGAGATGAGCATCTGCACGAGATGGCACTGGAGCAA
ATCACGGCAGTCACTACGGTGAATGATTCCAATTGTGACCAAGAACTTCTTTCCCTGCTCCTGGATGCCAAGCTGCTGGTGAAGTGTGTC
TCCACTCCCTTCTATCCACGTATTGTTGACCACCTCTTGGCTAGCCTCCAGCAAGGGCGCTGGGATGCAGAGGAGCTGGGCAGACACCTG
CGGGAGGCCGGCCATGAAGCCGAAGCCGGGTCTCTCCTTCTGGCCGTGAGGGGGACTCACCAGGCCTTCAGAACCTTCAGTACAGCCCTC
CGCGCAGCACAGCACTGGGTGTGAGGGCCACCTGTGGCCCTGCTCCTTAGCAGAAAAAGCATCTGGAGTTGAATGCTGTTCCCAGAAGCA

>22908_22908_2_DIS3L2-NBAS_DIS3L2_chr2_233164829_ENST00000325385_NBAS_chr2_15523441_ENST00000441750_length(amino acids)=1877AA_BP=592
MDLERRVTLEPIMSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPK
KFHEAFIPSPDGDRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEA
QFDGSDSEDGHGITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKN
SELFRKYALFSPSDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFS
SEVLECLPQGLPWTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQ
KVVPMLPRLLCEELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQA
VLNLHGIAKQLRQQRFVDGALRLDQLKLAFTLDHETGLPQGCHIYEYRESNKQPPVSESHWRTLLQDMLTMQQNVYTCLDSDACYEIFTE
SLLCSSRLENIHLAGQMMHCSACSENPPAGIAHKGKPHYRVSYEKSIDLVLAASREYFNSSTNLTDSCMDLARCCLQLITDRPPAIQEEL
DLIQAVGCLEEFGVKILPLQVRLCPDRISLIKECISQSPTCYKQSTKLLGLAELLRVAGENPEERRGQVLILLVEQALRFHDYKAASMHC
QELMATGYPKSWDVCSQLGQSEGYQDLATRQELMAFALTHCPPSSIELLLAASSSLQTEILYQRVNFQIHHEGGENISASPLTSKAVQED
EVGVPGSNSADLLRWTTATTMKVLSNTTTTTKAVLQAVSDGQWWKKSLTYLRPLQGQKCGGAYQIGTTANEDLEKQGCHPFYESVISNPF
VAESEGTYDTYQHVPVESFAEVLLRTGKLAEAKNKGEVFPTTEVLLQLASEALPNDMTLALAYLLALPQVLDANRCFEKQSPSALSLQLA
AYYYSLQIYARLAPCFRDKCHPLYRADPKELIKMVTRHVTRHEHEAWPEDLISLTKQLHCYNERLLDFTQAQILQGLRKGVDVQRFTADD
QYKRETILGLAETLEESVYSIAISLAQRYSVSRWEVFMTHLEFLFTDSGLSTLEIENRAQDLHLFETLKTDPEAFHQHMVKYIYPTIGGF
DHERLQYYFTLLENCGCADLGNCAIKPETHIRLLKKFKVVASGLNYKKLTDENMSPLEALEPVLSSQNILSISKLVPKIPEKDGQMLSPS
SLYTIWLQKLFWTGDPHLIKQVPGSSPEWLHAYDVCMKYFDRLHPGDLITVVDAVTFSPKAVTKLSVEARKEMTRKAIKTVKHFIEKPRK
RNSEDEAQEAKDSKVTYADTLNHLEKSLAHLETLSHSFILSLKNSEQETLQKYSHLYDLSRSEKEKLHDEAVAICLDGQPLAMIQQLLEV
AVGPLDISPKDIVQSAIMKIISALSGGSADLGGPRDPLKVLEGVVAAVHASVDKGEELVSPEDLLEWLRPFCADDAWPVRPRIHVLQILG
QSFHLTEEDSKLLVFFRTEAILKASWPQRQVDIADIENEENRYCLFMELLESSHHEAEFQHLVLLLQAWPPMKSEYVITNNPWVRLATVM
LTRCTMENKEGLGNEVLKMCRSLYNTKQMLPAEGVKELCLLLLNQSLLLPSLKLLLESRDEHLHEMALEQITAVTTVNDSNCDQELLSLL

--------------------------------------------------------------
>22908_22908_3_DIS3L2-NBAS_DIS3L2_chr2_233164829_ENST00000409307_NBAS_chr2_15523441_ENST00000281513_length(transcript)=5737nt_BP=1739nt
ATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCT
TCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCA
GAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGT
GATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCAT
TGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTC
CCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGC
ATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACA
AAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAG
AAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCC
TCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTG
TTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAG
CCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCA
TGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGAGACCTC
GATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCGGAGGGA
TCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTGTGTGAG
GAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGATGAATGG
TTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATCCCTGCG
AAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAGTTACGC
CAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTAAAGCTTGCTTTCACTCTGGACCACGAGACCGGATTGCCTCAAGGATGT
CATATCTATGAGTACCGCGAGAGCAACAAGCAGCCTCCTGTCAGTGAGTCTCATTGGAGAACGTTGCTGCAAGACATGTTAACTATGCAG
CAGAATGTATACACATGTCTAGATTCTGATGCCTGCTATGAGATATTTACAGAAAGCCTTCTGTGCTCTAGTCGCCTTGAAAACATCCAC
CTGGCTGGACAGATGATGCACTGCAGTGCTTGTTCAGAAAATCCTCCAGCTGGTATAGCCCATAAAGGGAAACCCCACTACAGGGTCAGC
TACGAAAAGAGTATTGACTTGGTTTTGGCTGCCAGCAGAGAGTACTTCAATTCTTCTACCAACCTCACTGATAGCTGCATGGATCTAGCC
AGGTGCTGCTTACAACTGATAACAGACAGACCCCCTGCCATTCAAGAGGAGCTAGATCTTATCCAAGCCGTTGGATGTCTTGAAGAATTT
GGGGTAAAGATCCTGCCTTTGCAAGTGCGATTGTGCCCTGATCGGATCAGTCTCATCAAGGAGTGTATTTCCCAGTCCCCCACATGCTAT
AAACAATCCACCAAGCTTCTGGGCCTTGCTGAGCTGCTGAGGGTTGCAGGTGAGAACCCAGAAGAAAGGCGGGGACAGGTTCTAATCCTT
TTAGTGGAGCAGGCACTTCGCTTCCATGACTACAAAGCAGCCAGTATGCATTGTCAGGAGCTGATGGCCACAGGTTATCCTAAAAGTTGG
GATGTTTGTAGCCAGTTAGGACAATCAGAAGGTTACCAGGACTTGGCCACTCGTCAAGAGCTCATGGCTTTTGCTTTGACACATTGCCCT
CCTAGCAGCATTGAACTTCTTTTGGCAGCTAGCAGCTCTCTGCAGACAGAAATTCTTTATCAAAGAGTGAATTTCCAGATCCATCATGAA
GGAGGGGAAAATATCAGTGCTTCACCATTAACTAGTAAAGCAGTACAAGAGGATGAAGTAGGTGTTCCAGGTAGCAATTCAGCTGACCTA
TTGCGCTGGACCACTGCTACCACCATGAAAGTCCTTTCCAACACCACAACCACCACCAAAGCGGTGCTGCAGGCCGTCAGTGATGGGCAG
TGGTGGAAGAAGTCTTTAACTTACCTTCGACCCCTTCAGGGGCAAAAATGTGGTGGTGCATATCAAATCGGAACTACAGCCAATGAAGAT
CTAGAGAAACAAGGGTGTCATCCTTTTTATGAATCTGTCATCTCAAATCCTTTTGTCGCTGAGTCTGAAGGGACCTATGACACCTATCAG
CATGTTCCAGTGGAAAGCTTTGCAGAAGTATTGCTGAGAACTGGAAAATTGGCAGAGGCTAAAAATAAAGGAGAAGTATTTCCAACAACT
GAAGTTCTCTTGCAACTAGCAAGTGAAGCCTTGCCAAATGACATGACCTTGGCTCTTGCTTACCTTCTTGCCTTACCACAAGTGTTAGAT
GCTAACCGGTGCTTTGAAAAGCAGTCCCCCTCTGCATTATCTCTCCAGCTGGCAGCGTATTACTATAGCCTCCAGATCTATGCCCGATTG
GCCCCATGTTTCAGGGACAAGTGCCATCCTCTTTACAGGGCTGATCCCAAAGAACTAATCAAGATGGTCACCAGGCATGTGACTCGACAT
GAGCACGAAGCCTGGCCTGAAGACCTTATTTCACTGACCAAGCAGTTACACTGCTACAATGAACGTCTCCTGGATTTCACTCAGGCGCAG
ATCCTTCAGGGCCTTCGGAAGGGTGTGGACGTGCAGCGGTTTACTGCAGATGACCAGTATAAAAGGGAAACTATCCTTGGTCTGGCAGAA
ACTCTAGAGGAAAGCGTCTACAGCATTGCTATTTCTCTGGCACAACGTTACAGTGTCTCCCGCTGGGAAGTTTTTATGACCCATTTGGAG
TTCCTCTTCACGGACAGTGGTTTGTCCACACTAGAAATTGAAAATAGAGCCCAAGACCTTCATCTCTTTGAGACTTTGAAGACTGATCCA
GAAGCCTTTCACCAGCACATGGTCAAGTATATTTACCCTACTATTGGTGGCTTTGATCACGAAAGGCTGCAGTATTATTTCACTCTTCTG
GAAAACTGTGGCTGTGCAGATTTGGGGAACTGTGCCATTAAACCAGAAACCCACATTCGACTGCTGAAGAAGTTTAAGGTTGTTGCATCA
GGTCTTAATTACAAAAAGCTGACAGATGAAAACATGAGTCCTCTTGAAGCATTGGAGCCAGTTCTTTCAAGTCAAAATATCTTGTCTATT
TCCAAACTTGTTCCCAAAATCCCTGAAAAGGATGGACAGATGCTTTCCCCAAGCTCTCTGTACACCATCTGGTTACAGAAGTTGTTCTGG
ACTGGAGACCCTCATCTCATTAAACAAGTCCCAGGCTCTTCACCGGAGTGGCTTCATGCCTATGATGTCTGCATGAAGTACTTTGATCGT
CTCCACCCAGGTGACCTCATCACTGTGGTAGATGCAGTTACATTTTCTCCAAAAGCTGTGACCAAGCTGTCTGTGGAAGCCCGTAAAGAG
ATGACTAGAAAGGCTATTAAGACAGTCAAACATTTTATTGAGAAGCCAAGGAAAAGAAACTCAGAAGACGAAGCTCAAGAAGCTAAGGAT
TCTAAAGTTACCTATGCAGATACTTTGAATCATCTGGAGAAATCACTTGCCCACCTGGAAACCCTGAGCCACAGCTTCATCCTTTCTCTG
AAGAATAGTGAGCAGGAAACACTGCAAAAATACAGTCACCTCTATGATCTGTCCCGATCAGAAAAAGAGAAACTTCATGATGAAGCTGTG
GCTATTTGTTTAGATGGTCAGCCTCTAGCAATGATTCAGCAGCTGCTAGAGGTGGCAGTTGGCCCTCTTGACATCTCACCCAAGGATATA
GTGCAGAGTGCAATCATGAAAATAATTTCTGCATTGAGTGGTGGCAGTGCTGACCTTGGTGGGCCAAGGGACCCACTGAAGGTCCTGGAA
GGTGTTGTTGCAGCAGTCCACGCCAGTGTGGACAAGGGTGAGGAGCTGGTTTCACCTGAGGACCTGCTGGAGTGGCTGCGGCCTTTCTGT
GCTGATGACGCCTGGCCGGTGCGGCCCCGCATTCACGTGCTGCAGATTTTGGGGCAATCATTTCACCTGACTGAGGAGGACAGCAAGCTC
CTCGTGTTCTTTAGAACTGAAGCCATTCTCAAAGCCTCCTGGCCCCAGAGACAGGTAGACATAGCTGACATTGAGAATGAAGAGAACCGC
TACTGTCTATTCATGGAACTCCTGGAATCTAGTCACCACGAGGCTGAATTTCAGCACTTGGTTTTACTTTTGCAAGCTTGGCCACCTATG
AAAAGTGAATATGTCATAACCAATAATCCATGGGTGAGACTAGCTACAGTGATGCTAACCAGATGTACGATGGAGAACAAGGAAGGATTG
GGGAATGAAGTTTTGAAAATGTGTCGCTCTTTGTATAACACCAAGCAGATGCTGCCTGCAGAGGGTGTGAAGGAGCTGTGTCTGCTGCTG
CTTAACCAGTCCCTCCTGCTTCCATCTCTGAAACTTCTCCTCGAGAGCCGAGATGAGCATCTGCACGAGATGGCACTGGAGCAAATCACG
GCAGTCACTACGGTGAATGATTCCAATTGTGACCAAGAACTTCTTTCCCTGCTCCTGGATGCCAAGCTGCTGGTGAAGTGTGTCTCCACT
CCCTTCTATCCACGTATTGTTGACCACCTCTTGGCTAGCCTCCAGCAAGGGCGCTGGGATGCAGAGGAGCTGGGCAGACACCTGCGGGAG
GCCGGCCATGAAGCCGAAGCCGGGTCTCTCCTTCTGGCCGTGAGGGGGACTCACCAGGCCTTCAGAACCTTCAGTACAGCCCTCCGCGCA
GCACAGCACTGGGTGTGAGGGCCACCTGTGGCCCTGCTCCTTAGCAGAAAAAGCATCTGGAGTTGAATGCTGTTCCCAGAAGCAACATGT

>22908_22908_3_DIS3L2-NBAS_DIS3L2_chr2_233164829_ENST00000409307_NBAS_chr2_15523441_ENST00000281513_length(amino acids)=1865AA_BP=580
MSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDG
DRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEAQFDGSDSEDGHG
ITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKNSELFRKYALFSP
SDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLP
WTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQKVVPMLPRLLCE
ELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAKQLR
QQRFVDGALRLDQLKLAFTLDHETGLPQGCHIYEYRESNKQPPVSESHWRTLLQDMLTMQQNVYTCLDSDACYEIFTESLLCSSRLENIH
LAGQMMHCSACSENPPAGIAHKGKPHYRVSYEKSIDLVLAASREYFNSSTNLTDSCMDLARCCLQLITDRPPAIQEELDLIQAVGCLEEF
GVKILPLQVRLCPDRISLIKECISQSPTCYKQSTKLLGLAELLRVAGENPEERRGQVLILLVEQALRFHDYKAASMHCQELMATGYPKSW
DVCSQLGQSEGYQDLATRQELMAFALTHCPPSSIELLLAASSSLQTEILYQRVNFQIHHEGGENISASPLTSKAVQEDEVGVPGSNSADL
LRWTTATTMKVLSNTTTTTKAVLQAVSDGQWWKKSLTYLRPLQGQKCGGAYQIGTTANEDLEKQGCHPFYESVISNPFVAESEGTYDTYQ
HVPVESFAEVLLRTGKLAEAKNKGEVFPTTEVLLQLASEALPNDMTLALAYLLALPQVLDANRCFEKQSPSALSLQLAAYYYSLQIYARL
APCFRDKCHPLYRADPKELIKMVTRHVTRHEHEAWPEDLISLTKQLHCYNERLLDFTQAQILQGLRKGVDVQRFTADDQYKRETILGLAE
TLEESVYSIAISLAQRYSVSRWEVFMTHLEFLFTDSGLSTLEIENRAQDLHLFETLKTDPEAFHQHMVKYIYPTIGGFDHERLQYYFTLL
ENCGCADLGNCAIKPETHIRLLKKFKVVASGLNYKKLTDENMSPLEALEPVLSSQNILSISKLVPKIPEKDGQMLSPSSLYTIWLQKLFW
TGDPHLIKQVPGSSPEWLHAYDVCMKYFDRLHPGDLITVVDAVTFSPKAVTKLSVEARKEMTRKAIKTVKHFIEKPRKRNSEDEAQEAKD
SKVTYADTLNHLEKSLAHLETLSHSFILSLKNSEQETLQKYSHLYDLSRSEKEKLHDEAVAICLDGQPLAMIQQLLEVAVGPLDISPKDI
VQSAIMKIISALSGGSADLGGPRDPLKVLEGVVAAVHASVDKGEELVSPEDLLEWLRPFCADDAWPVRPRIHVLQILGQSFHLTEEDSKL
LVFFRTEAILKASWPQRQVDIADIENEENRYCLFMELLESSHHEAEFQHLVLLLQAWPPMKSEYVITNNPWVRLATVMLTRCTMENKEGL
GNEVLKMCRSLYNTKQMLPAEGVKELCLLLLNQSLLLPSLKLLLESRDEHLHEMALEQITAVTTVNDSNCDQELLSLLLDAKLLVKCVST

--------------------------------------------------------------
>22908_22908_4_DIS3L2-NBAS_DIS3L2_chr2_233164829_ENST00000409307_NBAS_chr2_15523441_ENST00000441750_length(transcript)=5738nt_BP=1739nt
ATGAGCCATCCTGACTACAGAATGAACCTCCGGCCCCTGGGGACCCCCAGAGGTGTGTCTGCTGTGGCTGGTCCACATGACATTGGTGCT
TCGCCAGGTGACAAAAAGTCAAAGAACAGGTCCACACGAGGGAAGAAAAAGAGCATATTTGAAACTTACATGTCCAAGGAGGATGTTTCA
GAAGGCTTGAAGAGAGGAACACTCATCCAGGGTGTATTGAGAATTAATCCAAAGAAGTTTCATGAAGCCTTCATTCCTTCCCCGGATGGT
GATCGAGACATTTTTATTGATGGGGTTGTTGCTCGTAATAGAGCCTTAAATGGGGATCTGGTGGTCGTGAAACTGCTTCCCGAGGAGCAT
TGGAAGGTAGTTAAACCAGAGAGCAATGACAAAGAAACAGAAGCTGCGTATGAATCAGATATCCCCGAGGAGCTCTGTGGACACCATCTC
CCGCAACAGTCCCTGAAAAGCTATAATGACAGTCCTGATGTCATTGTAGAGGCTCAGTTTGATGGCAGCGACTCAGAAGATGGACATGGC
ATCACACAAAATGTGCTGGTTGATGGTGTTAAGAAACTCTCAGTTTGTGTTTCTGAGAAAGGAAGAGAGGATGGTGATGCACCGGTTACA
AAAGATGAGACCACCTGCATTTCACAAGACACAAGAGCTTTATCGGAGAAATCCCTGCAAAGATCAGCAAAGGTGGTTTACATCTTGGAG
AAAAAACATTCTCGAGCAGCAACCGGCTTCCTCAAACTCTTGGCTGATAAGAACAGCGAACTGTTTAGGAAATACGCCCTGTTTTCTCCC
TCAGACCACCGAGTGCCTAGAATTTATGTGCCTCTCAAGGACTGTCCCCAGGACTTTGTGGCACGGCCTAAAGATTATGCCAACACACTG
TTCATCTGCCGCATTGTGGACTGGAAGGAGGACTGCAATTTTGCCCTGGGGCAGCTGGCTAAGAGTCTTGGGCAGGCTGGTGAAATTGAG
CCTGAAACAGAAGGAATACTAACAGAGTATGGCGTGGATTTCTCTGATTTCTCTTCAGAAGTTCTAGAATGTCTTCCTCAAGGCCTGCCA
TGGACAATTCCACCAGAGGAGTTCAGCAAGAGAAGGGATTTAAGAAAAGACTGTATCTTCACCATTGACCCATCAACCGCCCGAGACCTC
GATGATGCCCTCTCCTGCAAGCCACTCGCTGACGGCAACTTCAAAGTGGGAGTTCACATTGCTGACGTGAGTTACTTTGTTCCGGAGGGA
TCTGATCTGGATAAAGTGGCTGCCGAGAGGGCTACAAGCGTCTACTTGGTTCAAAAGGTGGTCCCCATGCTTCCCAGGCTGCTGTGTGAG
GAGCTGTGCAGCCTCAACCCCATGTCCGACAAGCTGACCTTCTCTGTGATCTGGACACTGACTCCAGAGGGCAAGATCCTTGATGAATGG
TTTGGCCGGACCATCATCCGCTCCTGCACCAAACTTAGCTACGAGCATGCACAGAGCATGATTGAAAGCCCAACTGAGAAAATCCCTGCG
AAAGAGCTGCCCCCCATTTCCCCAGAGCATAGCAGCGAGGAGGTACACCAGGCCGTCTTGAATCTCCACGGAATTGCCAAGCAGTTACGC
CAGCAGCGCTTTGTGGACGGCGCACTTCGTTTGGATCAGCTAAAGCTTGCTTTCACTCTGGACCACGAGACCGGATTGCCTCAAGGATGT
CATATCTATGAGTACCGCGAGAGCAACAAGCAGCCTCCTGTCAGTGAGTCTCATTGGAGAACGTTGCTGCAAGACATGTTAACTATGCAG
CAGAATGTATACACATGTCTAGATTCTGATGCCTGCTATGAGATATTTACAGAAAGCCTTCTGTGCTCTAGTCGCCTTGAAAACATCCAC
CTGGCTGGACAGATGATGCACTGCAGTGCTTGTTCAGAAAATCCTCCAGCTGGTATAGCCCATAAAGGGAAACCCCACTACAGGGTCAGC
TACGAAAAGAGTATTGACTTGGTTTTGGCTGCCAGCAGAGAGTACTTCAATTCTTCTACCAACCTCACTGATAGCTGCATGGATCTAGCC
AGGTGCTGCTTACAACTGATAACAGACAGACCCCCTGCCATTCAAGAGGAGCTAGATCTTATCCAAGCCGTTGGATGTCTTGAAGAATTT
GGGGTAAAGATCCTGCCTTTGCAAGTGCGATTGTGCCCTGATCGGATCAGTCTCATCAAGGAGTGTATTTCCCAGTCCCCCACATGCTAT
AAACAATCCACCAAGCTTCTGGGCCTTGCTGAGCTGCTGAGGGTTGCAGGTGAGAACCCAGAAGAAAGGCGGGGACAGGTTCTAATCCTT
TTAGTGGAGCAGGCACTTCGCTTCCATGACTACAAAGCAGCCAGTATGCATTGTCAGGAGCTGATGGCCACAGGTTATCCTAAAAGTTGG
GATGTTTGTAGCCAGTTAGGACAATCAGAAGGTTACCAGGACTTGGCCACTCGTCAAGAGCTCATGGCTTTTGCTTTGACACATTGCCCT
CCTAGCAGCATTGAACTTCTTTTGGCAGCTAGCAGCTCTCTGCAGACAGAAATTCTTTATCAAAGAGTGAATTTCCAGATCCATCATGAA
GGAGGGGAAAATATCAGTGCTTCACCATTAACTAGTAAAGCAGTACAAGAGGATGAAGTAGGTGTTCCAGGTAGCAATTCAGCTGACCTA
TTGCGCTGGACCACTGCTACCACCATGAAAGTCCTTTCCAACACCACAACCACCACCAAAGCGGTGCTGCAGGCCGTCAGTGATGGGCAG
TGGTGGAAGAAGTCTTTAACTTACCTTCGACCCCTTCAGGGGCAAAAATGTGGTGGTGCATATCAAATCGGAACTACAGCCAATGAAGAT
CTAGAGAAACAAGGGTGTCATCCTTTTTATGAATCTGTCATCTCAAATCCTTTTGTCGCTGAGTCTGAAGGGACCTATGACACCTATCAG
CATGTTCCAGTGGAAAGCTTTGCAGAAGTATTGCTGAGAACTGGAAAATTGGCAGAGGCTAAAAATAAAGGAGAAGTATTTCCAACAACT
GAAGTTCTCTTGCAACTAGCAAGTGAAGCCTTGCCAAATGACATGACCTTGGCTCTTGCTTACCTTCTTGCCTTACCACAAGTGTTAGAT
GCTAACCGGTGCTTTGAAAAGCAGTCCCCCTCTGCATTATCTCTCCAGCTGGCAGCGTATTACTATAGCCTCCAGATCTATGCCCGATTG
GCCCCATGTTTCAGGGACAAGTGCCATCCTCTTTACAGGGCTGATCCCAAAGAACTAATCAAGATGGTCACCAGGCATGTGACTCGACAT
GAGCACGAAGCCTGGCCTGAAGACCTTATTTCACTGACCAAGCAGTTACACTGCTACAATGAACGTCTCCTGGATTTCACTCAGGCGCAG
ATCCTTCAGGGCCTTCGGAAGGGTGTGGACGTGCAGCGGTTTACTGCAGATGACCAGTATAAAAGGGAAACTATCCTTGGTCTGGCAGAA
ACTCTAGAGGAAAGCGTCTACAGCATTGCTATTTCTCTGGCACAACGTTACAGTGTCTCCCGCTGGGAAGTTTTTATGACCCATTTGGAG
TTCCTCTTCACGGACAGTGGTTTGTCCACACTAGAAATTGAAAATAGAGCCCAAGACCTTCATCTCTTTGAGACTTTGAAGACTGATCCA
GAAGCCTTTCACCAGCACATGGTCAAGTATATTTACCCTACTATTGGTGGCTTTGATCACGAAAGGCTGCAGTATTATTTCACTCTTCTG
GAAAACTGTGGCTGTGCAGATTTGGGGAACTGTGCCATTAAACCAGAAACCCACATTCGACTGCTGAAGAAGTTTAAGGTTGTTGCATCA
GGTCTTAATTACAAAAAGCTGACAGATGAAAACATGAGTCCTCTTGAAGCATTGGAGCCAGTTCTTTCAAGTCAAAATATCTTGTCTATT
TCCAAACTTGTTCCCAAAATCCCTGAAAAGGATGGACAGATGCTTTCCCCAAGCTCTCTGTACACCATCTGGTTACAGAAGTTGTTCTGG
ACTGGAGACCCTCATCTCATTAAACAAGTCCCAGGCTCTTCACCGGAGTGGCTTCATGCCTATGATGTCTGCATGAAGTACTTTGATCGT
CTCCACCCAGGTGACCTCATCACTGTGGTAGATGCAGTTACATTTTCTCCAAAAGCTGTGACCAAGCTGTCTGTGGAAGCCCGTAAAGAG
ATGACTAGAAAGGCTATTAAGACAGTCAAACATTTTATTGAGAAGCCAAGGAAAAGAAACTCAGAAGACGAAGCTCAAGAAGCTAAGGAT
TCTAAAGTTACCTATGCAGATACTTTGAATCATCTGGAGAAATCACTTGCCCACCTGGAAACCCTGAGCCACAGCTTCATCCTTTCTCTG
AAGAATAGTGAGCAGGAAACACTGCAAAAATACAGTCACCTCTATGATCTGTCCCGATCAGAAAAAGAGAAACTTCATGATGAAGCTGTG
GCTATTTGTTTAGATGGTCAGCCTCTAGCAATGATTCAGCAGCTGCTAGAGGTGGCAGTTGGCCCTCTTGACATCTCACCCAAGGATATA
GTGCAGAGTGCAATCATGAAAATAATTTCTGCATTGAGTGGTGGCAGTGCTGACCTTGGTGGGCCAAGGGACCCACTGAAGGTCCTGGAA
GGTGTTGTTGCAGCAGTCCACGCCAGTGTGGACAAGGGTGAGGAGCTGGTTTCACCTGAGGACCTGCTGGAGTGGCTGCGGCCTTTCTGT
GCTGATGACGCCTGGCCGGTGCGGCCCCGCATTCACGTGCTGCAGATTTTGGGGCAATCATTTCACCTGACTGAGGAGGACAGCAAGCTC
CTCGTGTTCTTTAGAACTGAAGCCATTCTCAAAGCCTCCTGGCCCCAGAGACAGGTAGACATAGCTGACATTGAGAATGAAGAGAACCGC
TACTGTCTATTCATGGAACTCCTGGAATCTAGTCACCACGAGGCTGAATTTCAGCACTTGGTTTTACTTTTGCAAGCTTGGCCACCTATG
AAAAGTGAATATGTCATAACCAATAATCCATGGGTGAGACTAGCTACAGTGATGCTAACCAGATGTACGATGGAGAACAAGGAAGGATTG
GGGAATGAAGTTTTGAAAATGTGTCGCTCTTTGTATAACACCAAGCAGATGCTGCCTGCAGAGGGTGTGAAGGAGCTGTGTCTGCTGCTG
CTTAACCAGTCCCTCCTGCTTCCATCTCTGAAACTTCTCCTCGAGAGCCGAGATGAGCATCTGCACGAGATGGCACTGGAGCAAATCACG
GCAGTCACTACGGTGAATGATTCCAATTGTGACCAAGAACTTCTTTCCCTGCTCCTGGATGCCAAGCTGCTGGTGAAGTGTGTCTCCACT
CCCTTCTATCCACGTATTGTTGACCACCTCTTGGCTAGCCTCCAGCAAGGGCGCTGGGATGCAGAGGAGCTGGGCAGACACCTGCGGGAG
GCCGGCCATGAAGCCGAAGCCGGGTCTCTCCTTCTGGCCGTGAGGGGGACTCACCAGGCCTTCAGAACCTTCAGTACAGCCCTCCGCGCA
GCACAGCACTGGGTGTGAGGGCCACCTGTGGCCCTGCTCCTTAGCAGAAAAAGCATCTGGAGTTGAATGCTGTTCCCAGAAGCAACATGT

>22908_22908_4_DIS3L2-NBAS_DIS3L2_chr2_233164829_ENST00000409307_NBAS_chr2_15523441_ENST00000441750_length(amino acids)=1865AA_BP=580
MSHPDYRMNLRPLGTPRGVSAVAGPHDIGASPGDKKSKNRSTRGKKKSIFETYMSKEDVSEGLKRGTLIQGVLRINPKKFHEAFIPSPDG
DRDIFIDGVVARNRALNGDLVVVKLLPEEHWKVVKPESNDKETEAAYESDIPEELCGHHLPQQSLKSYNDSPDVIVEAQFDGSDSEDGHG
ITQNVLVDGVKKLSVCVSEKGREDGDAPVTKDETTCISQDTRALSEKSLQRSAKVVYILEKKHSRAATGFLKLLADKNSELFRKYALFSP
SDHRVPRIYVPLKDCPQDFVARPKDYANTLFICRIVDWKEDCNFALGQLAKSLGQAGEIEPETEGILTEYGVDFSDFSSEVLECLPQGLP
WTIPPEEFSKRRDLRKDCIFTIDPSTARDLDDALSCKPLADGNFKVGVHIADVSYFVPEGSDLDKVAAERATSVYLVQKVVPMLPRLLCE
ELCSLNPMSDKLTFSVIWTLTPEGKILDEWFGRTIIRSCTKLSYEHAQSMIESPTEKIPAKELPPISPEHSSEEVHQAVLNLHGIAKQLR
QQRFVDGALRLDQLKLAFTLDHETGLPQGCHIYEYRESNKQPPVSESHWRTLLQDMLTMQQNVYTCLDSDACYEIFTESLLCSSRLENIH
LAGQMMHCSACSENPPAGIAHKGKPHYRVSYEKSIDLVLAASREYFNSSTNLTDSCMDLARCCLQLITDRPPAIQEELDLIQAVGCLEEF
GVKILPLQVRLCPDRISLIKECISQSPTCYKQSTKLLGLAELLRVAGENPEERRGQVLILLVEQALRFHDYKAASMHCQELMATGYPKSW
DVCSQLGQSEGYQDLATRQELMAFALTHCPPSSIELLLAASSSLQTEILYQRVNFQIHHEGGENISASPLTSKAVQEDEVGVPGSNSADL
LRWTTATTMKVLSNTTTTTKAVLQAVSDGQWWKKSLTYLRPLQGQKCGGAYQIGTTANEDLEKQGCHPFYESVISNPFVAESEGTYDTYQ
HVPVESFAEVLLRTGKLAEAKNKGEVFPTTEVLLQLASEALPNDMTLALAYLLALPQVLDANRCFEKQSPSALSLQLAAYYYSLQIYARL
APCFRDKCHPLYRADPKELIKMVTRHVTRHEHEAWPEDLISLTKQLHCYNERLLDFTQAQILQGLRKGVDVQRFTADDQYKRETILGLAE
TLEESVYSIAISLAQRYSVSRWEVFMTHLEFLFTDSGLSTLEIENRAQDLHLFETLKTDPEAFHQHMVKYIYPTIGGFDHERLQYYFTLL
ENCGCADLGNCAIKPETHIRLLKKFKVVASGLNYKKLTDENMSPLEALEPVLSSQNILSISKLVPKIPEKDGQMLSPSSLYTIWLQKLFW
TGDPHLIKQVPGSSPEWLHAYDVCMKYFDRLHPGDLITVVDAVTFSPKAVTKLSVEARKEMTRKAIKTVKHFIEKPRKRNSEDEAQEAKD
SKVTYADTLNHLEKSLAHLETLSHSFILSLKNSEQETLQKYSHLYDLSRSEKEKLHDEAVAICLDGQPLAMIQQLLEVAVGPLDISPKDI
VQSAIMKIISALSGGSADLGGPRDPLKVLEGVVAAVHASVDKGEELVSPEDLLEWLRPFCADDAWPVRPRIHVLQILGQSFHLTEEDSKL
LVFFRTEAILKASWPQRQVDIADIENEENRYCLFMELLESSHHEAEFQHLVLLLQAWPPMKSEYVITNNPWVRLATVMLTRCTMENKEGL
GNEVLKMCRSLYNTKQMLPAEGVKELCLLLLNQSLLLPSLKLLLESRDEHLHEMALEQITAVTTVNDSNCDQELLSLLLDAKLLVKCVST

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Fusion Gene PPI Analysis for DIS3L2-NBAS


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneNBASchr2:233164829chr2:15523441ENST0000044175025501036_2371965.66666666666662252.0ZW10 and RINT1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneNBASchr2:233164829chr2:15523441ENST0000028151327521_10351085.66666666666672372.0USE1L
TgeneNBASchr2:233164829chr2:15523441ENST0000044175025501_1035965.66666666666662252.0USE1L
TgeneNBASchr2:233164829chr2:15523441ENST0000028151327521036_23711085.66666666666672372.0ZW10 and RINT1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DIS3L2-NBAS


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DIS3L2-NBAS


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource