FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:DLK1-CCT5 (FusionGDB2 ID:23190)

Fusion Gene Summary for DLK1-CCT5

check button Fusion gene summary
Fusion gene informationFusion gene name: DLK1-CCT5
Fusion gene ID: 23190
HgeneTgene
Gene symbol

DLK1

CCT5

Gene ID

8788

22948

Gene namedelta like non-canonical Notch ligand 1chaperonin containing TCP1 subunit 5
SynonymsDLK|DLK-1|Delta1|FA1|PREF1|Pref-1|ZOG|pG2CCT-epsilon|CCTE|HEL-S-69|PNAS-102|TCP-1-epsilon
Cytomap

14q32.2

5p15.2

Type of geneprotein-codingprotein-coding
Descriptionprotein delta homolog 1delta-like 1 homologfetal antigen 1preadipocyte factor 1secredeltinT-complex protein 1 subunit epsilonchaperonin containing TCP1, subunit 5 (epsilon)epididymis secretory protein Li 69
Modification date2020032920200313
UniProtAcc

P80370

P48643

Ensembl transtripts involved in fusion geneENST00000341267, ENST00000331224, 
ENST00000556051, 		ENST00000280326, 
ENST00000503026, ENST00000506600, 
ENST00000515390, ENST00000515676, 
Fusion gene scores* DoF score8 X 7 X 4=22458 X 14 X 17=13804
# samples 961
** MAII scorelog2(9/224*10)=-1.31550182572793
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(61/13804*10)=-4.50013332598527
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DLK1 [Title/Abstract] AND CCT5 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDLK1(101201464)-CCT5(10250033), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneDLK1

GO:0045746

negative regulation of Notch signaling pathway

25093684


check buttonFusion gene breakpoints across DLK1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CCT5 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4UCSTCGA-NG-A4VU-01ADLK1chr14

101201464

-CCT5chr5

10250033

+


Top

Fusion Gene ORF analysis for DLK1-CCT5

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000341267ENST00000280326DLK1chr14

101201464

-CCT5chr5

10250033

+
3UTR-intronENST00000341267ENST00000503026DLK1chr14

101201464

-CCT5chr5

10250033

+
3UTR-intronENST00000341267ENST00000506600DLK1chr14

101201464

-CCT5chr5

10250033

+
3UTR-intronENST00000341267ENST00000515390DLK1chr14

101201464

-CCT5chr5

10250033

+
3UTR-intronENST00000341267ENST00000515676DLK1chr14

101201464

-CCT5chr5

10250033

+
5CDS-intronENST00000331224ENST00000503026DLK1chr14

101201464

-CCT5chr5

10250033

+
5CDS-intronENST00000331224ENST00000506600DLK1chr14

101201464

-CCT5chr5

10250033

+
5CDS-intronENST00000331224ENST00000515390DLK1chr14

101201464

-CCT5chr5

10250033

+
5CDS-intronENST00000331224ENST00000515676DLK1chr14

101201464

-CCT5chr5

10250033

+
In-frameENST00000331224ENST00000280326DLK1chr14

101201464

-CCT5chr5

10250033

+
intron-3CDSENST00000556051ENST00000280326DLK1chr14

101201464

-CCT5chr5

10250033

+
intron-intronENST00000556051ENST00000503026DLK1chr14

101201464

-CCT5chr5

10250033

+
intron-intronENST00000556051ENST00000506600DLK1chr14

101201464

-CCT5chr5

10250033

+
intron-intronENST00000556051ENST00000515390DLK1chr14

101201464

-CCT5chr5

10250033

+
intron-intronENST00000556051ENST00000515676DLK1chr14

101201464

-CCT5chr5

10250033

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000331224DLK1chr14101201464-ENST00000280326CCT5chr510250033+4999132417143369551

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000331224ENST00000280326DLK1chr14101201464-CCT5chr510250033+0.0013972030.9986028

Top

Fusion Genomic Features for DLK1-CCT5


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for DLK1-CCT5


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:101201464/chr5:10250033)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DLK1

P80370

CCT5

P48643

FUNCTION: May have a role in neuroendocrine differentiation.FUNCTION: Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis (PubMed:25467444). The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance (PubMed:25467444). As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia (PubMed:20080638). The TRiC complex plays a role in the folding of actin and tubulin (Probable). {ECO:0000269|PubMed:20080638, ECO:0000269|PubMed:25467444, ECO:0000305}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDLK1chr14:101201464chr5:10250033ENST00000331224-66127_168388311.0DomainEGF-like 4
HgeneDLK1chr14:101201464chr5:10250033ENST00000331224-66170_206388311.0DomainEGF-like 5
HgeneDLK1chr14:101201464chr5:10250033ENST00000331224-66208_245388311.0DomainEGF-like 6
HgeneDLK1chr14:101201464chr5:10250033ENST00000331224-6624_55388311.0DomainEGF-like 1
HgeneDLK1chr14:101201464chr5:10250033ENST00000331224-6653_86388311.0DomainEGF-like 2
HgeneDLK1chr14:101201464chr5:10250033ENST00000331224-6688_125388311.0DomainEGF-like 3
HgeneDLK1chr14:101201464chr5:10250033ENST00000331224-6624_303388311.0Topological domainExtracellular
HgeneDLK1chr14:101201464chr5:10250033ENST00000331224-66328_383388311.0Topological domainCytoplasmic
HgeneDLK1chr14:101201464chr5:10250033ENST00000331224-66304_327388311.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDLK1chr14:101201464chr5:10250033ENST00000341267-15127_1680384.0DomainEGF-like 4
HgeneDLK1chr14:101201464chr5:10250033ENST00000341267-15170_2060384.0DomainEGF-like 5
HgeneDLK1chr14:101201464chr5:10250033ENST00000341267-15208_2450384.0DomainEGF-like 6
HgeneDLK1chr14:101201464chr5:10250033ENST00000341267-1524_550384.0DomainEGF-like 1
HgeneDLK1chr14:101201464chr5:10250033ENST00000341267-1553_860384.0DomainEGF-like 2
HgeneDLK1chr14:101201464chr5:10250033ENST00000341267-1588_1250384.0DomainEGF-like 3
HgeneDLK1chr14:101201464chr5:10250033ENST00000341267-1524_3030384.0Topological domainExtracellular
HgeneDLK1chr14:101201464chr5:10250033ENST00000341267-15328_3830384.0Topological domainCytoplasmic
HgeneDLK1chr14:101201464chr5:10250033ENST00000341267-15304_3270384.0TransmembraneHelical


Top

Fusion Gene Sequence for DLK1-CCT5


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>23190_23190_1_DLK1-CCT5_DLK1_chr14_101201464_ENST00000331224_CCT5_chr5_10250033_ENST00000280326_length(transcript)=4999nt_BP=1324nt
GGCGGTGGAGAGCGCAGCGCGCAGCCCGGTGCAGCCCTGGCTTTCCCCTCGCTGCGCGCCCGCGCCCCCTTTCGCGTCCGCAACCAGAAG
CCCAGTGCGGCGCCAGGAGCCGGACCCGCGCCCGCACCGCTCCCGGGACCGCGACCCCGGCCGCCCAGAGATGACCGCGACCGAAGCCCT
CCTGCGCGTCCTCTTGCTCCTGCTGGCTTTCGGCCACAGCACCTATGGGGCTGAATGCTTCCCGGCCTGCAACCCCCAAAATGGATTCTG
CGAGGATGACAATGTTTGCAGGTGCCAGCCTGGCTGGCAGGGTCCCCTTTGTGACCAGTGCGTGACCTCTCCCGGCTGCCTTCACGGACT
CTGTGGAGAACCCGGGCAGTGCATTTGCACCGACGGCTGGGACGGGGAGCTCTGTGATAGAGATGTTCGGGCCTGCTCCTCGGCCCCCTG
TGCCAACAACAGGACCTGCGTGAGCCTGGACGATGGCCTCTATGAATGCTCCTGTGCCCCCGGGTACTCGGGAAAGGACTGCCAGAAAAA
GGACGGGCCCTGTGTGATCAACGGCTCCCCCTGCCAGCACGGAGGCACCTGCGTGGATGATGAGGGCCGGGCCTCCCATGCCTCCTGCCT
GTGCCCCCCTGGCTTCTCAGGCAATTTCTGCGAGATCGTGGCCAACAGCTGCACCCCCAACCCATGCGAGAACGACGGCGTCTGCACTGA
CATTGGGGGCGACTTCCGCTGCCGGTGCCCAGCCGGCTTCATCGACAAGACCTGCAGCCGCCCGGTGACCAACTGCGCCAGCAGCCCGTG
CCAGAACGGGGGCACCTGCCTGCAGCACACCCAGGGCCAGGCCATCTGCTTCACCATCCTGGGCGTGCTCACCAGCCTGGTGGTGCTGGG
CACTGTGGGTATCGTCTTCCTCAACAAGTGCGAGACCTGGGTGTCCAACCTGCGCTACAACCACATGCTGCGGAAGAAGAAGAACCTGCT
GCTTCAGTACAACAGCGGGGAGGACCTGGCCGTCAACATCATCTTCCCCGAGAAGATCGACATGACCACCTTCAGCAAGGAGGCCGGCGA
CGAGGAGATCTAAGCAGCGTTCCCACAGCCCCCTCTAGATTCTTGGAGTTCCGCAGAGCTTACTATACGCGGTCTGTCCTAATCTTTGTG
GTGTTCGCTATCTCTTGTGTCAAATCTGGTGAACGCTACGCTTACATATATTGTCTTTGTGCTGCTGTGTGACAAACGCAATGCAAAAAC
AATCCTCTTTCTCTCTCTTAATGCATGATACAGAATAATAATAAGAATTTCATCTTTAAATGAGAAAAAAAAAAAAAACCGGAAATGGGT
CCTACCATCTTCTCGGAGCCGGAGTGCGAAGAAATAAAGAAATAGTGCTTTAAGTCAATGAATTCCTCCTTGGGACCCACTATCGAGAAA
CTATCAGTGGTAACGTTTTAAAAAATGACAAATTCAATCTGCTCTTGACTTGTGTGTCCTAAGATTTCCACTAAGTGTCTTCAAACCTCC
CCCTCCCCGGCTTCCTGGATAATAGAAGTTCCCGAAGGCCGCCGATTCCAGAAGATACTGTCTGGCGTGAAATTAGTCTCAGTAGAAACA
TAAGTCCCGCGCGTCTTGTGCTGCGCGTGCGCAAGCTTTTGGGCCCTCCCGAGAAAGGGAAGTGCATTCTCGCTTCCGTAGCGGTCTCCG
CCGGTTGGGGGGAAGTAATTCCGGTTGTTGCACCATGGCGTCCATGGGGACCCTCGCCTTCGATGAATATGGGCGCCCTTTCCTCATCAT
CAAGGATCAGGACCGCAAGTCCCGTCTTATGGGACTTGAGGCCCTCAAGTCTCATATAATGGCAGCAAAGGCTGTAGCAAATACAATGAG
AACATCACTTGGACCAAATGGGCTTGATAAGATGATGGTGGATAAGGATGGAGATGTGACTGTAACTAATGATGGGGCCACCATCTTAAG
CATGATGGATGTTGATCATCAGATTGCCAAGCTGATGGTGGAACTGTCCAAGTCTCAGGATGATGAAATTGGAGATGGAACCACAGGAGT
GGTTGTCCTGGCTGGTGCCTTGTTAGAAGAAGCGGAGCAATTGCTAGACCGAGGCATTCACCCAATCAGAATAGCCGATGGCTATGAGCA
GGCTGCTCGTGTTGCTATTGAACACCTGGACAAGATCAGCGATAGCGTCCTTGTTGACATAAAGGACACCGAACCCCTGATTCAGACAGC
AAAAACCACGCTGGGCTCCAAAGTGGTCAACAGTTGTCACCGACAGATGGCTGAGATTGCTGTGAATGCCGTCCTCACTGTAGCAGATAT
GGAGCGGAGAGACGTTGACTTTGAGCTTATCAAAGTAGAAGGCAAAGTGGGCGGCAGGCTGGAGGACACTAAACTGATTAAGGGCGTGAT
TGTGGACAAGGATTTCAGTCACCCACAGATGCCAAAAAAAGTGGAAGATGCGAAGATTGCAATTCTCACATGTCCATTTGAACCACCCAA
ACCAAAAACAAAGCATAAGCTGGATGTGACCTCTGTCGAAGATTATAAAGCCCTTCAGAAATACGAAAAGGAGAAATTTGAAGAGATGAT
TCAACAAATTAAAGAGACTGGTGCTAACCTAGCAATTTGTCAGTGGGGCTTTGATGATGAAGCAAATCACTTACTTCTTCAGAACAACTT
GCCTGCGGTTCGCTGGGTAGGAGGACCTGAAATTGAGCTGATTGCCATCGCAACAGGAGGGCGGATCGTCCCCAGGTTCTCAGAGCTCAC
AGCCGAGAAGCTGGGCTTTGCTGGTCTTGTACAGGAGATCTCATTTGGGACAACTAAGGATAAAATGCTGGTCATCGAGCAGTGTAAGAA
CTCCAGAGCTGTAACCATTTTTATTAGAGGAGGAAATAAGATGATCATTGAGGAGGCGAAACGATCCCTTCACGATGCTTTGTGTGTCAT
CCGGAACCTCATCCGCGATAATCGTGTGGTGTATGGAGGAGGGGCTGCTGAGATATCCTGTGCCCTGGCAGTTAGCCAAGAGGCGGATAA
GTGCCCCACCTTAGAACAGTATGCCATGAGAGCGTTTGCCGACGCACTGGAGGTCATCCCCATGGCCCTCTCTGAAAACAGTGGCATGAA
TCCCATCCAGACTATGACCGAAGTCCGAGCCAGACAGGTGAAGGAGATGAACCCTGCTCTTGGCATCGACTGTTTGCACAAGGGGACAAA
TGATATGAAGCAACAGCATGTCATAGAAACCTTGATTGGCAAAAAGCAACAGATATCTCTTGCAACACAAATGGTTAGAATGATTTTGAA
GATTGATGACATTCGTAAGCCTGGAGAATCTGAAGAATGAAGACATTGAGAAAACTATGTAGCAAGATCCACTTCTGTGATTAAGTAAAT
GGATGTCTCGTGATGCATCTACAGTTATTTATTGTTACATCCTTTTCCAGACACTGTAGATGCTATAATAAAAATAGCTGTTTGGTAACC
ATAGTTTCACTTGTTCAAAGCTGTGTAATCGTGGGGGTACCATCTCAACTGCTTTTGTATTCATTGTATTAAAAGAATCTGTTTAAACAA
CCTTTATCTTCTCTTCGGGTTTAAGAAACGTTTATTGTAACAGTAATTAAATGCTGCCTTAATTGAAGGGGTTTGGGTGGATTTTTTTTT
CTCAAAATAAGCTGTAGGGACTATTTTAACAGCTTAAACAGGAGCTCTCAAGATGCACTTTCATATTGAGAGGAATATGGGCTTGATCCT
CTTCCTATCTAAATGGGTGGGCCATTTGATTGTAGAGGGTCCACCACAGAATTATGGGATGCCTTAAGTGCTGTTACTAGGTTGCTCACA
GCCTAACCTGGCGTGTTGTTTAGGGCTGATGGAGACCCATGTGAGCCTTTGCTTTCCTCTGGCCCCGGCCCCACCCTGAACACAGCTCAT
ACACAGAATCAGGACCAGCATGTGCAGAGCTGGCCACCAGCACAGGCTTAGGGCAGTTCAGAACCCACTTGTTTCCCTATCAGAGGGACA
CAGTGAAGTGGAGGTTAAAGTAAATTACAGGAAATAAGGGAGAAATCTTGCAGTTACCATGTTCAGATAGAGTGACTGAAATTAATTGTA
CTTACTAAAGTATTAACTAGCTAACAGTGATGGGCCAAGACGCTCCGAGAACTCTACCGGGATTGTCTGTTCTGACAACCCAGTGAGGCA
GATACACTTTCTTACTGCTCACATCTTACAGGTGAGTACTCATAATTGGCCAGCATCTCACCACCAGCAAGTAGTAGGGCCAGGTCAATC
CCAGGCAGTCTGACCCCAGAGTGGCCCAGCTCATCCCCTACTCTGTTATTTGCTTGTTAATGATTCTCTAGATTTTCTAAAATAATGTTT
CTTAGCATTGTGATGATAAAGCTCATGATGAACTTTATCACTAGTTATGCCACCTTAACTAGTCAGATTTCCTAGAATTAGGAAATGGTG
ACTCTTGTCTAAATTTGGTTAAGTGATGAATTTGGGTTACCGTCTCATGTGAACCTGGAGATTCACCAGTCTTAACTTTTGGGTCATTGT
GTTTTCTCTACATTCATGCATTGGATGTTTTGCTAAATAACTCCTGTGGATTTAGGAATGTGTGCTAATAGCAATCTTCCTAATTTTCAT
GTTTATATGGAACTATGCAGTTGAGTATTGAAAGCTTTAAACTGAGTTTATTTACAAGGACTGAGTCTAGCCTACAGAGAACATACAGCA
GCCTTCTTTGGACCACAGTCTTATCCGAGGGGTCTGTGGTTGTATCAGAAGAGCCACTAAACCAATCCCCCTTTCCAAAATTGAACCTCA
CAGACGTTCCTGTTTTTTGTGATTGAGAAACTGGTCAATGAACAGGAAGACTTAGAGATGTTTCACAAGCCTTTGATTTTTGTTTCATTT

>23190_23190_1_DLK1-CCT5_DLK1_chr14_101201464_ENST00000331224_CCT5_chr5_10250033_ENST00000280326_length(amino acids)=551AA_BP=
MGGSNSGCCTMASMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMVDKDGDVTVTNDGATILSM
MDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQLLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAK
TTLGSKVVNSCHRQMAEIAVNAVLTVADMERRDVDFELIKVEGKVGGRLEDTKLIKGVIVDKDFSHPQMPKKVEDAKIAILTCPFEPPKP
KTKHKLDVTSVEDYKALQKYEKEKFEEMIQQIKETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSELTA
EKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALCVIRNLIRDNRVVYGGGAAEISCALAVSQEADKC
PTLEQYAMRAFADALEVIPMALSENSGMNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQHVIETLIGKKQQISLATQMVRMILKI

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for DLK1-CCT5


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for DLK1-CCT5


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for DLK1-CCT5


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource