FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:DMD-TMEM117 (FusionGDB2 ID:23243)

Fusion Gene Summary for DMD-TMEM117

check button Fusion gene summary
Fusion gene informationFusion gene name: DMD-TMEM117
Fusion gene ID: 23243
HgeneTgene
Gene symbol

DMD

TMEM117

Gene ID

1756

84216

Gene namedystrophintransmembrane protein 117
SynonymsBMD|CMD3B|DXS142|DXS164|DXS206|DXS230|DXS239|DXS268|DXS269|DXS270|DXS272|MRX85-
Cytomap

Xp21.2-p21.1

12q12

Type of geneprotein-codingprotein-coding
Descriptiondystrophintransmembrane protein 117
Modification date2020032920200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000357033, ENST00000378677, 
ENST00000288447, ENST00000343523, 
ENST00000359836, ENST00000361471, 
ENST00000378680, ENST00000378702, 
ENST00000378707, ENST00000378723, 
ENST00000445312, ENST00000474231, 
ENST00000541735, 		ENST00000546978, 
ENST00000266534, ENST00000536799, 
ENST00000551577, 
Fusion gene scores* DoF score32 X 35 X 5=560011 X 10 X 5=550
# samples 3611
** MAII scorelog2(36/5600*10)=-3.95935801550265
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/550*10)=-2.32192809488736
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DMD [Title/Abstract] AND TMEM117 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDMD(32536125)-TMEM117(44605073), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneDMD

GO:0043043

peptide biosynthetic process

16000376


check buttonFusion gene breakpoints across DMD (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TMEM117 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A240-01ADMDchrX

32536125

-TMEM117chr12

44605073

+


Top

Fusion Gene ORF analysis for DMD-TMEM117

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000357033ENST00000546978DMDchrX

32536125

-TMEM117chr12

44605073

+
5CDS-intronENST00000378677ENST00000546978DMDchrX

32536125

-TMEM117chr12

44605073

+
In-frameENST00000357033ENST00000266534DMDchrX

32536125

-TMEM117chr12

44605073

+
In-frameENST00000357033ENST00000536799DMDchrX

32536125

-TMEM117chr12

44605073

+
In-frameENST00000357033ENST00000551577DMDchrX

32536125

-TMEM117chr12

44605073

+
In-frameENST00000378677ENST00000266534DMDchrX

32536125

-TMEM117chr12

44605073

+
In-frameENST00000378677ENST00000536799DMDchrX

32536125

-TMEM117chr12

44605073

+
In-frameENST00000378677ENST00000551577DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000288447ENST00000266534DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000288447ENST00000536799DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000288447ENST00000551577DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000343523ENST00000266534DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000343523ENST00000536799DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000343523ENST00000551577DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000359836ENST00000266534DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000359836ENST00000536799DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000359836ENST00000551577DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000361471ENST00000266534DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000361471ENST00000536799DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000361471ENST00000551577DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000378680ENST00000266534DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000378680ENST00000536799DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000378680ENST00000551577DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000378702ENST00000266534DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000378702ENST00000536799DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000378702ENST00000551577DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000378707ENST00000266534DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000378707ENST00000536799DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000378707ENST00000551577DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000378723ENST00000266534DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000378723ENST00000536799DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000378723ENST00000551577DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000445312ENST00000266534DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000445312ENST00000536799DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000445312ENST00000551577DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000474231ENST00000266534DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000474231ENST00000536799DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000474231ENST00000551577DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000541735ENST00000266534DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000541735ENST00000536799DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-3CDSENST00000541735ENST00000551577DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-intronENST00000288447ENST00000546978DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-intronENST00000343523ENST00000546978DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-intronENST00000359836ENST00000546978DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-intronENST00000361471ENST00000546978DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-intronENST00000378680ENST00000546978DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-intronENST00000378702ENST00000546978DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-intronENST00000378707ENST00000546978DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-intronENST00000378723ENST00000546978DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-intronENST00000445312ENST00000546978DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-intronENST00000474231ENST00000546978DMDchrX

32536125

-TMEM117chr12

44605073

+
intron-intronENST00000541735ENST00000546978DMDchrX

32536125

-TMEM117chr12

44605073

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000378677DMDchrX32536125-ENST00000551577TMEM117chr1244605073+446624751952771858
ENST00000378677DMDchrX32536125-ENST00000266534TMEM117chr1244605073+4596247519535091104
ENST00000378677DMDchrX32536125-ENST00000536799TMEM117chr1244605073+3510247519535091104
ENST00000357033DMDchrX32536125-ENST00000551577TMEM117chr1244605073+449024992072795862
ENST00000357033DMDchrX32536125-ENST00000266534TMEM117chr1244605073+4620249920735331108
ENST00000357033DMDchrX32536125-ENST00000536799TMEM117chr1244605073+3534249920735331108

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000378677ENST00000551577DMDchrX32536125-TMEM117chr1244605073+0.0007291330.99927086
ENST00000378677ENST00000266534DMDchrX32536125-TMEM117chr1244605073+0.0003916060.99960846
ENST00000378677ENST00000536799DMDchrX32536125-TMEM117chr1244605073+0.0005815310.9994185
ENST00000357033ENST00000551577DMDchrX32536125-TMEM117chr1244605073+0.0007103530.99928963
ENST00000357033ENST00000266534DMDchrX32536125-TMEM117chr1244605073+0.0003967740.9996032
ENST00000357033ENST00000536799DMDchrX32536125-TMEM117chr1244605073+0.0006132430.9993868

Top

Fusion Genomic Features for DMD-TMEM117


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DMDchrX32536124-TMEM117chr1244605072+1.03E-070.9999999
DMDchrX32536124-TMEM117chr1244605072+1.03E-070.9999999

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for DMD-TMEM117


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chrX:32536125/chr12:44605073)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTMEM117chrX:32536125chr12:44605073ENST0000026653438176_198170515.0Topological domainCytoplasmic
TgeneTMEM117chrX:32536125chr12:44605073ENST0000026653438220_239170515.0Topological domainExtracellular
TgeneTMEM117chrX:32536125chr12:44605073ENST0000026653438261_295170515.0Topological domainCytoplasmic
TgeneTMEM117chrX:32536125chr12:44605073ENST0000026653438317_394170515.0Topological domainExtracellular
TgeneTMEM117chrX:32536125chr12:44605073ENST0000026653438416_514170515.0Topological domainCytoplasmic
TgeneTMEM117chrX:32536125chr12:44605073ENST0000026653438199_219170515.0TransmembraneHelical
TgeneTMEM117chrX:32536125chr12:44605073ENST0000026653438240_260170515.0TransmembraneHelical
TgeneTMEM117chrX:32536125chr12:44605073ENST0000026653438296_316170515.0TransmembraneHelical
TgeneTMEM117chrX:32536125chr12:44605073ENST0000026653438395_415170515.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-116134_2400623.0DomainCalponin-homology (CH) 2
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-11615_1190623.0DomainCalponin-homology (CH) 1
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1163055_30880623.0DomainWW
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-113134_2400526.0DomainCalponin-homology (CH) 2
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-11315_1190526.0DomainCalponin-homology (CH) 1
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1133055_30880526.0DomainWW
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-118134_2400618.0DomainCalponin-homology (CH) 2
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-11815_1190618.0DomainCalponin-homology (CH) 1
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1183055_30880618.0DomainWW
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-117134_2400636.0DomainCalponin-homology (CH) 2
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-11715_1190636.0DomainCalponin-homology (CH) 1
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1173055_30880636.0DomainWW
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1161_2400623.0RegionNote=Actin-binding
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1163466_35180623.0RegionNote=Binds to SNTB1
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-11663_720623.0RegionANK2- and ANK-3 binding
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1131_2400526.0RegionNote=Actin-binding
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1133466_35180526.0RegionNote=Binds to SNTB1
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-11363_720526.0RegionANK2- and ANK-3 binding
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1181_2400618.0RegionNote=Actin-binding
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1183466_35180618.0RegionNote=Binds to SNTB1
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-11863_720618.0RegionANK2- and ANK-3 binding
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1171_2400636.0RegionNote=Actin-binding
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1173466_35180636.0RegionNote=Binds to SNTB1
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-11763_720636.0RegionANK2- and ANK-3 binding
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1161048_11540623.0RepeatNote=Spectrin 7
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1161157_12630623.0RepeatNote=Spectrin 8
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1161266_13670623.0RepeatNote=Spectrin 9
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1161368_14630623.0RepeatNote=Spectrin 10
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1161468_15680623.0RepeatNote=Spectrin 11
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1161571_16760623.0RepeatNote=Spectrin 12
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1161679_17780623.0RepeatNote=Spectrin 13
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1161779_18740623.0RepeatNote=Spectrin 14
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1161877_19790623.0RepeatNote=Spectrin 15
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1161992_21010623.0RepeatNote=Spectrin 16
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1162104_22080623.0RepeatNote=Spectrin 17
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1162211_23180623.0RepeatNote=Spectrin 18
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1162319_24230623.0RepeatNote=Spectrin 19
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1162475_25770623.0RepeatNote=Spectrin 20
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1162580_26860623.0RepeatNote=Spectrin 21
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1162689_28020623.0RepeatNote=Spectrin 22
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1162808_29300623.0RepeatNote=Spectrin 23
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1162935_30400623.0RepeatNote=Spectrin 24
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-116339_4470623.0RepeatNote=Spectrin 1
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-116448_5560623.0RepeatNote=Spectrin 2
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-116559_6670623.0RepeatNote=Spectrin 3
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-116719_8280623.0RepeatNote=Spectrin 4
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-116830_9340623.0RepeatNote=Spectrin 5
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-116943_10450623.0RepeatNote=Spectrin 6
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1131048_11540526.0RepeatNote=Spectrin 7
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1131157_12630526.0RepeatNote=Spectrin 8
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1131266_13670526.0RepeatNote=Spectrin 9
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1131368_14630526.0RepeatNote=Spectrin 10
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1131468_15680526.0RepeatNote=Spectrin 11
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1131571_16760526.0RepeatNote=Spectrin 12
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1131679_17780526.0RepeatNote=Spectrin 13
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1131779_18740526.0RepeatNote=Spectrin 14
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1131877_19790526.0RepeatNote=Spectrin 15
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1131992_21010526.0RepeatNote=Spectrin 16
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1132104_22080526.0RepeatNote=Spectrin 17
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1132211_23180526.0RepeatNote=Spectrin 18
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1132319_24230526.0RepeatNote=Spectrin 19
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1132475_25770526.0RepeatNote=Spectrin 20
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1132580_26860526.0RepeatNote=Spectrin 21
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1132689_28020526.0RepeatNote=Spectrin 22
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1132808_29300526.0RepeatNote=Spectrin 23
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1132935_30400526.0RepeatNote=Spectrin 24
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-113339_4470526.0RepeatNote=Spectrin 1
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-113448_5560526.0RepeatNote=Spectrin 2
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-113559_6670526.0RepeatNote=Spectrin 3
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-113719_8280526.0RepeatNote=Spectrin 4
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-113830_9340526.0RepeatNote=Spectrin 5
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-113943_10450526.0RepeatNote=Spectrin 6
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1181048_11540618.0RepeatNote=Spectrin 7
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1181157_12630618.0RepeatNote=Spectrin 8
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1181266_13670618.0RepeatNote=Spectrin 9
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1181368_14630618.0RepeatNote=Spectrin 10
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1181468_15680618.0RepeatNote=Spectrin 11
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1181571_16760618.0RepeatNote=Spectrin 12
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1181679_17780618.0RepeatNote=Spectrin 13
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1181779_18740618.0RepeatNote=Spectrin 14
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1181877_19790618.0RepeatNote=Spectrin 15
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1181992_21010618.0RepeatNote=Spectrin 16
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1182104_22080618.0RepeatNote=Spectrin 17
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1182211_23180618.0RepeatNote=Spectrin 18
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1182319_24230618.0RepeatNote=Spectrin 19
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1182475_25770618.0RepeatNote=Spectrin 20
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1182580_26860618.0RepeatNote=Spectrin 21
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1182689_28020618.0RepeatNote=Spectrin 22
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1182808_29300618.0RepeatNote=Spectrin 23
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1182935_30400618.0RepeatNote=Spectrin 24
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-118339_4470618.0RepeatNote=Spectrin 1
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-118448_5560618.0RepeatNote=Spectrin 2
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-118559_6670618.0RepeatNote=Spectrin 3
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-118719_8280618.0RepeatNote=Spectrin 4
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-118830_9340618.0RepeatNote=Spectrin 5
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-118943_10450618.0RepeatNote=Spectrin 6
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1171048_11540636.0RepeatNote=Spectrin 7
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1171157_12630636.0RepeatNote=Spectrin 8
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1171266_13670636.0RepeatNote=Spectrin 9
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1171368_14630636.0RepeatNote=Spectrin 10
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1171468_15680636.0RepeatNote=Spectrin 11
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1171571_16760636.0RepeatNote=Spectrin 12
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1171679_17780636.0RepeatNote=Spectrin 13
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1171779_18740636.0RepeatNote=Spectrin 14
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1171877_19790636.0RepeatNote=Spectrin 15
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1171992_21010636.0RepeatNote=Spectrin 16
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1172104_22080636.0RepeatNote=Spectrin 17
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1172211_23180636.0RepeatNote=Spectrin 18
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1172319_24230636.0RepeatNote=Spectrin 19
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1172475_25770636.0RepeatNote=Spectrin 20
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1172580_26860636.0RepeatNote=Spectrin 21
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1172689_28020636.0RepeatNote=Spectrin 22
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1172808_29300636.0RepeatNote=Spectrin 23
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1172935_30400636.0RepeatNote=Spectrin 24
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-117339_4470636.0RepeatNote=Spectrin 1
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-117448_5560636.0RepeatNote=Spectrin 2
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-117559_6670636.0RepeatNote=Spectrin 3
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-117719_8280636.0RepeatNote=Spectrin 4
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-117830_9340636.0RepeatNote=Spectrin 5
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-117943_10450636.0RepeatNote=Spectrin 6
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1163307_33540623.0Zinc fingerZZ-type
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1133307_33540526.0Zinc fingerZZ-type
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1183307_33540618.0Zinc fingerZZ-type
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1173307_33540636.0Zinc fingerZZ-type
TgeneTMEM117chrX:32536125chr12:44605073ENST0000026653438132_154170515.0Topological domainExtracellular
TgeneTMEM117chrX:32536125chr12:44605073ENST00000266534381_15170515.0Topological domainCytoplasmic
TgeneTMEM117chrX:32536125chr12:44605073ENST000002665343837_65170515.0Topological domainExtracellular
TgeneTMEM117chrX:32536125chr12:44605073ENST000002665343887_110170515.0Topological domainCytoplasmic
TgeneTMEM117chrX:32536125chr12:44605073ENST0000026653438111_131170515.0TransmembraneHelical
TgeneTMEM117chrX:32536125chr12:44605073ENST0000026653438155_175170515.0TransmembraneHelical
TgeneTMEM117chrX:32536125chr12:44605073ENST000002665343816_36170515.0TransmembraneHelical
TgeneTMEM117chrX:32536125chr12:44605073ENST000002665343866_86170515.0TransmembraneHelical


Top

Fusion Gene Sequence for DMD-TMEM117


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>23243_23243_1_DMD-TMEM117_DMD_chrX_32536125_ENST00000357033_TMEM117_chr12_44605073_ENST00000266534_length(transcript)=4620nt_BP=2499nt
GGGATCACTCACTTTCCCCCTACAGGACTCAGATCTGGGAGGCAATTACCTTCGGAGAAAAACGAATAGGAAAAACTGAAGTGTTACTTT
TTTTAAAGCTGCTGAAGTTTGTTGGTTTCTCATTGTTTTTAAGCCTACTGGAGCAATAAAGTTTGAAGAACTTTTACCAGGTTTTTTTTA
TCGCTGCCTTGATATACACTTTTCAAAATGCTTTGGTGGGAAGAAGTAGAGGACTGTTATGAAAGAGAAGATGTTCAAAAGAAAACATTC
ACAAAATGGGTAAATGCACAATTTTCTAAGTTTGGGAAGCAGCATATTGAGAACCTCTTCAGTGACCTACAGGATGGGAGGCGCCTCCTA
GACCTCCTCGAAGGCCTGACAGGGCAAAAACTGCCAAAAGAAAAAGGATCCACAAGAGTTCATGCCCTGAACAATGTCAACAAGGCACTG
CGGGTTTTGCAGAACAATAATGTTGATTTAGTGAATATTGGAAGTACTGACATCGTAGATGGAAATCATAAACTGACTCTTGGTTTGATT
TGGAATATAATCCTCCACTGGCAGGTCAAAAATGTAATGAAAAATATCATGGCTGGATTGCAACAAACCAACAGTGAAAAGATTCTCCTG
AGCTGGGTCCGACAATCAACTCGTAATTATCCACAGGTTAATGTAATCAACTTCACCACCAGCTGGTCTGATGGCCTGGCTTTGAATGCT
CTCATCCATAGTCATAGGCCAGACCTATTTGACTGGAATAGTGTGGTTTGCCAGCAGTCAGCCACACAACGACTGGAACATGCATTCAAC
ATCGCCAGATATCAATTAGGCATAGAGAAACTACTCGATCCTGAAGATGTTGATACCACCTATCCAGATAAGAAGTCCATCTTAATGTAC
ATCACATCACTCTTCCAAGTTTTGCCTCAACAAGTGAGCATTGAAGCCATCCAGGAAGTGGAAATGTTGCCAAGGCCACCTAAAGTGACT
AAAGAAGAACATTTTCAGTTACATCATCAAATGCACTATTCTCAACAGATCACGGTCAGTCTAGCACAGGGATATGAGAGAACTTCTTCC
CCTAAGCCTCGATTCAAGAGCTATGCCTACACACAGGCTGCTTATGTCACCACCTCTGACCCTACACGGAGCCCATTTCCTTCACAGCAT
TTGGAAGCTCCTGAAGACAAGTCATTTGGCAGTTCATTGATGGAGAGTGAAGTAAACCTGGACCGTTATCAAACAGCTTTAGAAGAAGTA
TTATCGTGGCTTCTTTCTGCTGAGGACACATTGCAAGCACAAGGAGAGATTTCTAATGATGTGGAAGTGGTGAAAGACCAGTTTCATACT
CATGAGGGGTACATGATGGATTTGACAGCCCATCAGGGCCGGGTTGGTAATATTCTACAATTGGGAAGTAAGCTGATTGGAACAGGAAAA
TTATCAGAAGATGAAGAAACTGAAGTACAAGAGCAGATGAATCTCCTAAATTCAAGATGGGAATGCCTCAGGGTAGCTAGCATGGAAAAA
CAAAGCAATTTACATAGAGTTTTAATGGATCTCCAGAATCAGAAACTGAAAGAGTTGAATGACTGGCTAACAAAAACAGAAGAAAGAACA
AGGAAAATGGAGGAAGAGCCTCTTGGACCTGATCTTGAAGACCTAAAACGCCAAGTACAACAACATAAGGTGCTTCAAGAAGATCTAGAA
CAAGAACAAGTCAGGGTCAATTCTCTCACTCACATGGTGGTGGTAGTTGATGAATCTAGTGGAGATCACGCAACTGCTGCTTTGGAAGAA
CAACTTAAGGTATTGGGAGATCGATGGGCAAACATCTGTAGATGGACAGAAGACCGCTGGGTTCTTTTACAAGACATCCTTCTCAAATGG
CAACGTCTTACTGAAGAACAGTGCCTTTTTAGTGCATGGCTTTCAGAAAAAGAAGATGCAGTGAACAAGATTCACACAACTGGCTTTAAA
GATCAAAATGAAATGTTATCAAGTCTTCAAAAACTGGCCGTTTTAAAAGCGGATCTAGAAAAGAAAAAGCAATCCATGGGCAAACTGTAT
TCACTCAAACAAGATCTTCTTTCAACACTGAAGAATAAGTCAGTGACCCAGAAGACGGAAGCATGGCTGGATAACTTTGCCCGGTGTTGG
GATAATTTAGTCCAAAAACTTGAAAAGAGTACAGCACAGATTTCACAGGCTGTCACCACCACTCAGCCATCACTAACACAGACAACTGTA
ATGGAAACAGTAACTACGGTGACCACAAGGGAACAGATCCTGGTAAAGCATGCTCAAGAGGAACTTCCACCACCACCTCCCCAAAAGAAG
AGGCAGATTACTGTGGATTCTGAAATTAGGAAAAGGTTGGATGTTGATATAACTGAACTTCACAGCTGGATTACTCGCTCAGAAGCTGTG
TTGCAGAGTCCTGAATTTGCAATCTTTCGGAAGGAAGGCAACTTCTCAGACTTAAAAGAAAAAGTCAATGTCACTGATATGATGCTTCAG
GACAAACCCTATCCTGACTGGGGAAAATCAGCAAGAGCTTTCTGGAAGAAAGGAAATGTTAGGATCACTTTATTCTGGACAGTTCTTTTT
ACTCTGACGTCTGTGGTTGTACTTGTGATTACAACGGACTGGATCAGCTGGGACAAGCTGAATCGGGGATTTTTGCCCAGTGATGAAGTT
TCCAGAGCATTCCTTGCTTCTTTTATCTTGGTCTTTGACCTTCTTATTGTGATGCAGGACTGGGAATTCCCACATTTCATGGGAGATGTT
GATGTAAATCTCCCTGGTTTGCACACCCCTCACATGCAGTTCAAGATTCCTTTCTTCCAGAAAATCTTCAAGGAGGAATATCGTATTCAC
ATAACAGGCAAATGGTTTAACTATGGAATTATCTTCCTCGTCTTGATTTTGGATCTTAATATGTGGAAGAACCAAATATTTTATAAACCT
CATGAATATGGGCAATATATCGGCCCGGGGCAGAAGATATATACAGTGAAAGACTCAGAAAGTTTAAAAGATTTGAACAGAACCAAGCTA
TCCTGGGAATGGAGGTCCAATCACACTAACCCTCGGACTAATAAAACATATGTTGAGGGAGACATGTTCTTACACAGCAGGTTCATAGGA
GCCAGTCTTGATGTCAAGTGTCTGGCCTTTGTTCCAAGCCTGATAGCCTTTGTGTGGTTTGGATTCTTTATTTGGTTCTTTGGACGATTT
TTGAAAAATGAGCCACGCATGGAGAATCAAGACAAAACTTACACTCGCATGAAAAGAAAATCTCCATCAGAACATAGCAAAGACATGGGA
ATCACTCGAGAAAACACCCAGGCTTCAGTAGAAGACCCCTTGAATGACCCTTCTTTGGTTTGCATCAGGTCTGACTTCAATGAGATCGTC
TACAAGTCTTCCCACCTAACCTCGGAAAACTTGAGCTCACAGTTGAACGAATCTACTAGTGCAACAGAAGCTGATCAAGACCCAACGACT
TCTAAAAGTACACCTACGAACTAGACTCGGAGATAGACTTGGAGATAACACAAAAAGCAACCTTGAGTGTAACTTTAAAAATTTAGTCTT
TCCTTTTGTATATGTAAGGTTTACGTAGTGTTAGGTAAAAATATGAACAATGCCACAACGGTGCTCAACATGCTTTTTCTAGGATTCATT
GTTTTCTATTTGTATTATAATACACGTGCCTACTGTATACTCAACAGTCCTCTAGAGATTGCTTTTCACAATTGCACAAGCTATTACTGA
CTTTACAGCATAGTGGAAGATTAGCTGATGACCCATGTATCTGATGTTCAACCATAGTGGTGCCTTGAGACATTAAACTGTTTTTAACTG
TACCAGAAATGAAGTGTGGAACAGTTACCTAACCTATTTCACATGGGCGTTTTGTATACAACTATTTTGATCTACACTTGATGTCTGAGC
AGAAAACAGAAATAGCTAAATGTGACTCAGGAAGTATCTCTTGGTTTCTTATTCAGCAGCAGAGTTGGTGACTTTGACAACTGGACTGCA
GAGAAACATGGTGATCACCTTTTAATTTTTATTGGCTGTCTGCCAAATATAAATACAGATGCAAAATTCAGTAATAGGAGATCCATAACC
CAACATGGGTCACTACTCGTGAAATGTGACTTTCTCCCACCAGTAATTGAAATGAGGTGATGATACCTAATTATGTTTTCCTAATTAAAG
ATAAATTGCTACTTGATTAAAAATCCTGCCCTTCACCTTTGGGAACAAAGGTTAAGAGACACAGTTGGGCGAACTCTCAAATTTATTGGC
ATTTACACAAAGTCCCAGACAACCAAGGAACTGAAGTTTTCATCATATGAGAGCAGCACATCCCACCATTTACAATATTCGTATATCTTT
CTGCAAATATGGCTCTGGATAGTGAAAATTGAAAAACATATGCCAACCCTGAGCAAGGGAACTCCTCAAAAAATCATGCAGCGGAACCTT
GTCAGGTAGAGAAGCCGTGCATGAAAGAATTTGTTTAATGTCTTGTTTTGCGTATGTGTTTTTTGTTTTTGTTTTTTAAGAACTAAATAT

>23243_23243_1_DMD-TMEM117_DMD_chrX_32536125_ENST00000357033_TMEM117_chr12_44605073_ENST00000266534_length(amino acids)=1108AA_BP=764
MLWWEEVEDCYEREDVQKKTFTKWVNAQFSKFGKQHIENLFSDLQDGRRLLDLLEGLTGQKLPKEKGSTRVHALNNVNKALRVLQNNNVD
LVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNVMKNIMAGLQQTNSEKILLSWVRQSTRNYPQVNVINFTTSWSDGLALNALIHSHRPDL
FDWNSVVCQQSATQRLEHAFNIARYQLGIEKLLDPEDVDTTYPDKKSILMYITSLFQVLPQQVSIEAIQEVEMLPRPPKVTKEEHFQLHH
QMHYSQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHLEAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAED
TLQAQGEISNDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIGTGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLM
DLQNQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRW
ANICRWTEDRWVLLQDILLKWQRLTEEQCLFSAWLSEKEDAVNKIHTTGFKDQNEMLSSLQKLAVLKADLEKKKQSMGKLYSLKQDLLST
LKNKSVTQKTEAWLDNFARCWDNLVQKLEKSTAQISQAVTTTQPSLTQTTVMETVTTVTTREQILVKHAQEELPPPPPQKKRQITVDSEI
RKRLDVDITELHSWITRSEAVLQSPEFAIFRKEGNFSDLKEKVNVTDMMLQDKPYPDWGKSARAFWKKGNVRITLFWTVLFTLTSVVVLV
ITTDWISWDKLNRGFLPSDEVSRAFLASFILVFDLLIVMQDWEFPHFMGDVDVNLPGLHTPHMQFKIPFFQKIFKEEYRIHITGKWFNYG
IIFLVLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWEWRSNHTNPRTNKTYVEGDMFLHSRFIGASLDVKCLA
FVPSLIAFVWFGFFIWFFGRFLKNEPRMENQDKTYTRMKRKSPSEHSKDMGITRENTQASVEDPLNDPSLVCIRSDFNEIVYKSSHLTSE

--------------------------------------------------------------
>23243_23243_2_DMD-TMEM117_DMD_chrX_32536125_ENST00000357033_TMEM117_chr12_44605073_ENST00000536799_length(transcript)=3534nt_BP=2499nt
GGGATCACTCACTTTCCCCCTACAGGACTCAGATCTGGGAGGCAATTACCTTCGGAGAAAAACGAATAGGAAAAACTGAAGTGTTACTTT
TTTTAAAGCTGCTGAAGTTTGTTGGTTTCTCATTGTTTTTAAGCCTACTGGAGCAATAAAGTTTGAAGAACTTTTACCAGGTTTTTTTTA
TCGCTGCCTTGATATACACTTTTCAAAATGCTTTGGTGGGAAGAAGTAGAGGACTGTTATGAAAGAGAAGATGTTCAAAAGAAAACATTC
ACAAAATGGGTAAATGCACAATTTTCTAAGTTTGGGAAGCAGCATATTGAGAACCTCTTCAGTGACCTACAGGATGGGAGGCGCCTCCTA
GACCTCCTCGAAGGCCTGACAGGGCAAAAACTGCCAAAAGAAAAAGGATCCACAAGAGTTCATGCCCTGAACAATGTCAACAAGGCACTG
CGGGTTTTGCAGAACAATAATGTTGATTTAGTGAATATTGGAAGTACTGACATCGTAGATGGAAATCATAAACTGACTCTTGGTTTGATT
TGGAATATAATCCTCCACTGGCAGGTCAAAAATGTAATGAAAAATATCATGGCTGGATTGCAACAAACCAACAGTGAAAAGATTCTCCTG
AGCTGGGTCCGACAATCAACTCGTAATTATCCACAGGTTAATGTAATCAACTTCACCACCAGCTGGTCTGATGGCCTGGCTTTGAATGCT
CTCATCCATAGTCATAGGCCAGACCTATTTGACTGGAATAGTGTGGTTTGCCAGCAGTCAGCCACACAACGACTGGAACATGCATTCAAC
ATCGCCAGATATCAATTAGGCATAGAGAAACTACTCGATCCTGAAGATGTTGATACCACCTATCCAGATAAGAAGTCCATCTTAATGTAC
ATCACATCACTCTTCCAAGTTTTGCCTCAACAAGTGAGCATTGAAGCCATCCAGGAAGTGGAAATGTTGCCAAGGCCACCTAAAGTGACT
AAAGAAGAACATTTTCAGTTACATCATCAAATGCACTATTCTCAACAGATCACGGTCAGTCTAGCACAGGGATATGAGAGAACTTCTTCC
CCTAAGCCTCGATTCAAGAGCTATGCCTACACACAGGCTGCTTATGTCACCACCTCTGACCCTACACGGAGCCCATTTCCTTCACAGCAT
TTGGAAGCTCCTGAAGACAAGTCATTTGGCAGTTCATTGATGGAGAGTGAAGTAAACCTGGACCGTTATCAAACAGCTTTAGAAGAAGTA
TTATCGTGGCTTCTTTCTGCTGAGGACACATTGCAAGCACAAGGAGAGATTTCTAATGATGTGGAAGTGGTGAAAGACCAGTTTCATACT
CATGAGGGGTACATGATGGATTTGACAGCCCATCAGGGCCGGGTTGGTAATATTCTACAATTGGGAAGTAAGCTGATTGGAACAGGAAAA
TTATCAGAAGATGAAGAAACTGAAGTACAAGAGCAGATGAATCTCCTAAATTCAAGATGGGAATGCCTCAGGGTAGCTAGCATGGAAAAA
CAAAGCAATTTACATAGAGTTTTAATGGATCTCCAGAATCAGAAACTGAAAGAGTTGAATGACTGGCTAACAAAAACAGAAGAAAGAACA
AGGAAAATGGAGGAAGAGCCTCTTGGACCTGATCTTGAAGACCTAAAACGCCAAGTACAACAACATAAGGTGCTTCAAGAAGATCTAGAA
CAAGAACAAGTCAGGGTCAATTCTCTCACTCACATGGTGGTGGTAGTTGATGAATCTAGTGGAGATCACGCAACTGCTGCTTTGGAAGAA
CAACTTAAGGTATTGGGAGATCGATGGGCAAACATCTGTAGATGGACAGAAGACCGCTGGGTTCTTTTACAAGACATCCTTCTCAAATGG
CAACGTCTTACTGAAGAACAGTGCCTTTTTAGTGCATGGCTTTCAGAAAAAGAAGATGCAGTGAACAAGATTCACACAACTGGCTTTAAA
GATCAAAATGAAATGTTATCAAGTCTTCAAAAACTGGCCGTTTTAAAAGCGGATCTAGAAAAGAAAAAGCAATCCATGGGCAAACTGTAT
TCACTCAAACAAGATCTTCTTTCAACACTGAAGAATAAGTCAGTGACCCAGAAGACGGAAGCATGGCTGGATAACTTTGCCCGGTGTTGG
GATAATTTAGTCCAAAAACTTGAAAAGAGTACAGCACAGATTTCACAGGCTGTCACCACCACTCAGCCATCACTAACACAGACAACTGTA
ATGGAAACAGTAACTACGGTGACCACAAGGGAACAGATCCTGGTAAAGCATGCTCAAGAGGAACTTCCACCACCACCTCCCCAAAAGAAG
AGGCAGATTACTGTGGATTCTGAAATTAGGAAAAGGTTGGATGTTGATATAACTGAACTTCACAGCTGGATTACTCGCTCAGAAGCTGTG
TTGCAGAGTCCTGAATTTGCAATCTTTCGGAAGGAAGGCAACTTCTCAGACTTAAAAGAAAAAGTCAATGTCACTGATATGATGCTTCAG
GACAAACCCTATCCTGACTGGGGAAAATCAGCAAGAGCTTTCTGGAAGAAAGGAAATGTTAGGATCACTTTATTCTGGACAGTTCTTTTT
ACTCTGACGTCTGTGGTTGTACTTGTGATTACAACGGACTGGATCAGCTGGGACAAGCTGAATCGGGGATTTTTGCCCAGTGATGAAGTT
TCCAGAGCATTCCTTGCTTCTTTTATCTTGGTCTTTGACCTTCTTATTGTGATGCAGGACTGGGAATTCCCACATTTCATGGGAGATGTT
GATGTAAATCTCCCTGGTTTGCACACCCCTCACATGCAGTTCAAGATTCCTTTCTTCCAGAAAATCTTCAAGGAGGAATATCGTATTCAC
ATAACAGGCAAATGGTTTAACTATGGAATTATCTTCCTCGTCTTGATTTTGGATCTTAATATGTGGAAGAACCAAATATTTTATAAACCT
CATGAATATGGGCAATATATCGGCCCGGGGCAGAAGATATATACAGTGAAAGACTCAGAAAGTTTAAAAGATTTGAACAGAACCAAGCTA
TCCTGGGAATGGAGGTCCAATCACACTAACCCTCGGACTAATAAAACATATGTTGAGGGAGACATGTTCTTACACAGCAGGTTCATAGGA
GCCAGTCTTGATGTCAAGTGTCTGGCCTTTGTTCCAAGCCTGATAGCCTTTGTGTGGTTTGGATTCTTTATTTGGTTCTTTGGACGATTT
TTGAAAAATGAGCCACGCATGGAGAATCAAGACAAAACTTACACTCGCATGAAAAGAAAATCTCCATCAGAACATAGCAAAGACATGGGA
ATCACTCGAGAAAACACCCAGGCTTCAGTAGAAGACCCCTTGAATGACCCTTCTTTGGTTTGCATCAGGTCTGACTTCAATGAGATCGTC
TACAAGTCTTCCCACCTAACCTCGGAAAACTTGAGCTCACAGTTGAACGAATCTACTAGTGCAACAGAAGCTGATCAAGACCCAACGACT

>23243_23243_2_DMD-TMEM117_DMD_chrX_32536125_ENST00000357033_TMEM117_chr12_44605073_ENST00000536799_length(amino acids)=1108AA_BP=764
MLWWEEVEDCYEREDVQKKTFTKWVNAQFSKFGKQHIENLFSDLQDGRRLLDLLEGLTGQKLPKEKGSTRVHALNNVNKALRVLQNNNVD
LVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNVMKNIMAGLQQTNSEKILLSWVRQSTRNYPQVNVINFTTSWSDGLALNALIHSHRPDL
FDWNSVVCQQSATQRLEHAFNIARYQLGIEKLLDPEDVDTTYPDKKSILMYITSLFQVLPQQVSIEAIQEVEMLPRPPKVTKEEHFQLHH
QMHYSQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHLEAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAED
TLQAQGEISNDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIGTGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLM
DLQNQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRW
ANICRWTEDRWVLLQDILLKWQRLTEEQCLFSAWLSEKEDAVNKIHTTGFKDQNEMLSSLQKLAVLKADLEKKKQSMGKLYSLKQDLLST
LKNKSVTQKTEAWLDNFARCWDNLVQKLEKSTAQISQAVTTTQPSLTQTTVMETVTTVTTREQILVKHAQEELPPPPPQKKRQITVDSEI
RKRLDVDITELHSWITRSEAVLQSPEFAIFRKEGNFSDLKEKVNVTDMMLQDKPYPDWGKSARAFWKKGNVRITLFWTVLFTLTSVVVLV
ITTDWISWDKLNRGFLPSDEVSRAFLASFILVFDLLIVMQDWEFPHFMGDVDVNLPGLHTPHMQFKIPFFQKIFKEEYRIHITGKWFNYG
IIFLVLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWEWRSNHTNPRTNKTYVEGDMFLHSRFIGASLDVKCLA
FVPSLIAFVWFGFFIWFFGRFLKNEPRMENQDKTYTRMKRKSPSEHSKDMGITRENTQASVEDPLNDPSLVCIRSDFNEIVYKSSHLTSE

--------------------------------------------------------------
>23243_23243_3_DMD-TMEM117_DMD_chrX_32536125_ENST00000357033_TMEM117_chr12_44605073_ENST00000551577_length(transcript)=4490nt_BP=2499nt
GGGATCACTCACTTTCCCCCTACAGGACTCAGATCTGGGAGGCAATTACCTTCGGAGAAAAACGAATAGGAAAAACTGAAGTGTTACTTT
TTTTAAAGCTGCTGAAGTTTGTTGGTTTCTCATTGTTTTTAAGCCTACTGGAGCAATAAAGTTTGAAGAACTTTTACCAGGTTTTTTTTA
TCGCTGCCTTGATATACACTTTTCAAAATGCTTTGGTGGGAAGAAGTAGAGGACTGTTATGAAAGAGAAGATGTTCAAAAGAAAACATTC
ACAAAATGGGTAAATGCACAATTTTCTAAGTTTGGGAAGCAGCATATTGAGAACCTCTTCAGTGACCTACAGGATGGGAGGCGCCTCCTA
GACCTCCTCGAAGGCCTGACAGGGCAAAAACTGCCAAAAGAAAAAGGATCCACAAGAGTTCATGCCCTGAACAATGTCAACAAGGCACTG
CGGGTTTTGCAGAACAATAATGTTGATTTAGTGAATATTGGAAGTACTGACATCGTAGATGGAAATCATAAACTGACTCTTGGTTTGATT
TGGAATATAATCCTCCACTGGCAGGTCAAAAATGTAATGAAAAATATCATGGCTGGATTGCAACAAACCAACAGTGAAAAGATTCTCCTG
AGCTGGGTCCGACAATCAACTCGTAATTATCCACAGGTTAATGTAATCAACTTCACCACCAGCTGGTCTGATGGCCTGGCTTTGAATGCT
CTCATCCATAGTCATAGGCCAGACCTATTTGACTGGAATAGTGTGGTTTGCCAGCAGTCAGCCACACAACGACTGGAACATGCATTCAAC
ATCGCCAGATATCAATTAGGCATAGAGAAACTACTCGATCCTGAAGATGTTGATACCACCTATCCAGATAAGAAGTCCATCTTAATGTAC
ATCACATCACTCTTCCAAGTTTTGCCTCAACAAGTGAGCATTGAAGCCATCCAGGAAGTGGAAATGTTGCCAAGGCCACCTAAAGTGACT
AAAGAAGAACATTTTCAGTTACATCATCAAATGCACTATTCTCAACAGATCACGGTCAGTCTAGCACAGGGATATGAGAGAACTTCTTCC
CCTAAGCCTCGATTCAAGAGCTATGCCTACACACAGGCTGCTTATGTCACCACCTCTGACCCTACACGGAGCCCATTTCCTTCACAGCAT
TTGGAAGCTCCTGAAGACAAGTCATTTGGCAGTTCATTGATGGAGAGTGAAGTAAACCTGGACCGTTATCAAACAGCTTTAGAAGAAGTA
TTATCGTGGCTTCTTTCTGCTGAGGACACATTGCAAGCACAAGGAGAGATTTCTAATGATGTGGAAGTGGTGAAAGACCAGTTTCATACT
CATGAGGGGTACATGATGGATTTGACAGCCCATCAGGGCCGGGTTGGTAATATTCTACAATTGGGAAGTAAGCTGATTGGAACAGGAAAA
TTATCAGAAGATGAAGAAACTGAAGTACAAGAGCAGATGAATCTCCTAAATTCAAGATGGGAATGCCTCAGGGTAGCTAGCATGGAAAAA
CAAAGCAATTTACATAGAGTTTTAATGGATCTCCAGAATCAGAAACTGAAAGAGTTGAATGACTGGCTAACAAAAACAGAAGAAAGAACA
AGGAAAATGGAGGAAGAGCCTCTTGGACCTGATCTTGAAGACCTAAAACGCCAAGTACAACAACATAAGGTGCTTCAAGAAGATCTAGAA
CAAGAACAAGTCAGGGTCAATTCTCTCACTCACATGGTGGTGGTAGTTGATGAATCTAGTGGAGATCACGCAACTGCTGCTTTGGAAGAA
CAACTTAAGGTATTGGGAGATCGATGGGCAAACATCTGTAGATGGACAGAAGACCGCTGGGTTCTTTTACAAGACATCCTTCTCAAATGG
CAACGTCTTACTGAAGAACAGTGCCTTTTTAGTGCATGGCTTTCAGAAAAAGAAGATGCAGTGAACAAGATTCACACAACTGGCTTTAAA
GATCAAAATGAAATGTTATCAAGTCTTCAAAAACTGGCCGTTTTAAAAGCGGATCTAGAAAAGAAAAAGCAATCCATGGGCAAACTGTAT
TCACTCAAACAAGATCTTCTTTCAACACTGAAGAATAAGTCAGTGACCCAGAAGACGGAAGCATGGCTGGATAACTTTGCCCGGTGTTGG
GATAATTTAGTCCAAAAACTTGAAAAGAGTACAGCACAGATTTCACAGGCTGTCACCACCACTCAGCCATCACTAACACAGACAACTGTA
ATGGAAACAGTAACTACGGTGACCACAAGGGAACAGATCCTGGTAAAGCATGCTCAAGAGGAACTTCCACCACCACCTCCCCAAAAGAAG
AGGCAGATTACTGTGGATTCTGAAATTAGGAAAAGGTTGGATGTTGATATAACTGAACTTCACAGCTGGATTACTCGCTCAGAAGCTGTG
TTGCAGAGTCCTGAATTTGCAATCTTTCGGAAGGAAGGCAACTTCTCAGACTTAAAAGAAAAAGTCAATGTCACTGATATGATGCTTCAG
GACAAACCCTATCCTGACTGGGGAAAATCAGCAAGAGCTTTCTGGAAGAAAGGAAATGTTAGGATCACTTTATTCTGGACAGTTCTTTTT
ACTCTGACGTCTGTGGTTGTACTTGTGATTACAACGGACTGGATCAGCTGGGACAAGCTGAATCGGGGATTTTTGCCCAGTGATGAAGTT
TCCAGAGCATTCCTTGCTTCTTTTATCTTGGTCTTTGACCTTCTTATTGTGATGCAGGCAAATGGTTTAACTATGGAATTATCTTCCTCG
TCTTGATTTTGGATCTTAATATGTGGAAGAACCAAATATTTTATAAACCTCATGAATATGGGCAATATATCGGCCCGGGGCAGAAGATAT
ATACAGTGAAAGACTCAGAAAGTTTAAAAGATTTGAACAGAACCAAGCTATCCTGGGAATGGAGGTCCAATCACACTAACCCTCGGACTA
ATAAAACATATGTTGAGGGAGACATGTTCTTACACAGCAGGTTCATAGGAGCCAGTCTTGATGTCAAGTGTCTGGCCTTTGTTCCAAGCC
TGATAGCCTTTGTGTGGTTTGGATTCTTTATTTGGTTCTTTGGACGATTTTTGAAAAATGAGCCACGCATGGAGAATCAAGACAAAACTT
ACACTCGCATGAAAAGAAAATCTCCATCAGAACATAGCAAAGACATGGGAATCACTCGAGAAAACACCCAGGCTTCAGTAGAAGACCCCT
TGAATGACCCTTCTTTGGTTTGCATCAGGTCTGACTTCAATGAGATCGTCTACAAGTCTTCCCACCTAACCTCGGAAAACTTGAGCTCAC
AGTTGAACGAATCTACTAGTGCAACAGAAGCTGATCAAGACCCAACGACTTCTAAAAGTACACCTACGAACTAGACTCGGAGATAGACTT
GGAGATAACACAAAAAGCAACCTTGAGTGTAACTTTAAAAATTTAGTCTTTCCTTTTGTATATGTAAGGTTTACGTAGTGTTAGGTAAAA
ATATGAACAATGCCACAACGGTGCTCAACATGCTTTTTCTAGGATTCATTGTTTTCTATTTGTATTATAATACACGTGCCTACTGTATAC
TCAACAGTCCTCTAGAGATTGCTTTTCACAATTGCACAAGCTATTACTGACTTTACAGCATAGTGGAAGATTAGCTGATGACCCATGTAT
CTGATGTTCAACCATAGTGGTGCCTTGAGACATTAAACTGTTTTTAACTGTACCAGAAATGAAGTGTGGAACAGTTACCTAACCTATTTC
ACATGGGCGTTTTGTATACAACTATTTTGATCTACACTTGATGTCTGAGCAGAAAACAGAAATAGCTAAATGTGACTCAGGAAGTATCTC
TTGGTTTCTTATTCAGCAGCAGAGTTGGTGACTTTGACAACTGGACTGCAGAGAAACATGGTGATCACCTTTTAATTTTTATTGGCTGTC
TGCCAAATATAAATACAGATGCAAAATTCAGTAATAGGAGATCCATAACCCAACATGGGTCACTACTCGTGAAATGTGACTTTCTCCCAC
CAGTAATTGAAATGAGGTGATGATACCTAATTATGTTTTCCTAATTAAAGATAAATTGCTACTTGATTAAAAATCCTGCCCTTCACCTTT
GGGAACAAAGGTTAAGAGACACAGTTGGGCGAACTCTCAAATTTATTGGCATTTACACAAAGTCCCAGACAACCAAGGAACTGAAGTTTT
CATCATATGAGAGCAGCACATCCCACCATTTACAATATTCGTATATCTTTCTGCAAATATGGCTCTGGATAGTGAAAATTGAAAAACATA
TGCCAACCCTGAGCAAGGGAACTCCTCAAAAAATCATGCAGCGGAACCTTGTCAGGTAGAGAAGCCGTGCATGAAAGAATTTGTTTAATG

>23243_23243_3_DMD-TMEM117_DMD_chrX_32536125_ENST00000357033_TMEM117_chr12_44605073_ENST00000551577_length(amino acids)=862AA_BP=764
MLWWEEVEDCYEREDVQKKTFTKWVNAQFSKFGKQHIENLFSDLQDGRRLLDLLEGLTGQKLPKEKGSTRVHALNNVNKALRVLQNNNVD
LVNIGSTDIVDGNHKLTLGLIWNIILHWQVKNVMKNIMAGLQQTNSEKILLSWVRQSTRNYPQVNVINFTTSWSDGLALNALIHSHRPDL
FDWNSVVCQQSATQRLEHAFNIARYQLGIEKLLDPEDVDTTYPDKKSILMYITSLFQVLPQQVSIEAIQEVEMLPRPPKVTKEEHFQLHH
QMHYSQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHLEAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAED
TLQAQGEISNDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIGTGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLM
DLQNQKLKELNDWLTKTEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRW
ANICRWTEDRWVLLQDILLKWQRLTEEQCLFSAWLSEKEDAVNKIHTTGFKDQNEMLSSLQKLAVLKADLEKKKQSMGKLYSLKQDLLST
LKNKSVTQKTEAWLDNFARCWDNLVQKLEKSTAQISQAVTTTQPSLTQTTVMETVTTVTTREQILVKHAQEELPPPPPQKKRQITVDSEI
RKRLDVDITELHSWITRSEAVLQSPEFAIFRKEGNFSDLKEKVNVTDMMLQDKPYPDWGKSARAFWKKGNVRITLFWTVLFTLTSVVVLV

--------------------------------------------------------------
>23243_23243_4_DMD-TMEM117_DMD_chrX_32536125_ENST00000378677_TMEM117_chr12_44605073_ENST00000266534_length(transcript)=4596nt_BP=2475nt
GTGCAAAAAGATTGTGTGTTTGTCTGCTTTTGTGAGGCTGGTCAGAGATTCTGTGCCTGCTTTATCTGTGCTTGGCTATGACTCTACCTC
CAGGTTTACCATACCCCATAGAATGTGTAAGAGAAAAGTACCAACAGGGAAATCAGCAAAAAGCTTTCCTATGAAGGTGTGTAGCCAGCC
TCCGCAGAATTTGAAATGTCTGAGGTCTCATCTGATGAAAGAGAAGATGTTCAAAAGAAAACATTCACAAAATGGGTAAATGCACAATTT
TCTAAGTTTGGGAAGCAGCATATTGAGAACCTCTTCAGTGACCTACAGGATGGGAGGCGCCTCCTAGACCTCCTCGAAGGCCTGACAGGG
CAAAAACTGCCAAAAGAAAAAGGATCCACAAGAGTTCATGCCCTGAACAATGTCAACAAGGCACTGCGGGTTTTGCAGAACAATAATGTT
GATTTAGTGAATATTGGAAGTACTGACATCGTAGATGGAAATCATAAACTGACTCTTGGTTTGATTTGGAATATAATCCTCCACTGGCAG
GTCAAAAATGTAATGAAAAATATCATGGCTGGATTGCAACAAACCAACAGTGAAAAGATTCTCCTGAGCTGGGTCCGACAATCAACTCGT
AATTATCCACAGGTTAATGTAATCAACTTCACCACCAGCTGGTCTGATGGCCTGGCTTTGAATGCTCTCATCCATAGTCATAGGCCAGAC
CTATTTGACTGGAATAGTGTGGTTTGCCAGCAGTCAGCCACACAACGACTGGAACATGCATTCAACATCGCCAGATATCAATTAGGCATA
GAGAAACTACTCGATCCTGAAGATGTTGATACCACCTATCCAGATAAGAAGTCCATCTTAATGTACATCACATCACTCTTCCAAGTTTTG
CCTCAACAAGTGAGCATTGAAGCCATCCAGGAAGTGGAAATGTTGCCAAGGCCACCTAAAGTGACTAAAGAAGAACATTTTCAGTTACAT
CATCAAATGCACTATTCTCAACAGATCACGGTCAGTCTAGCACAGGGATATGAGAGAACTTCTTCCCCTAAGCCTCGATTCAAGAGCTAT
GCCTACACACAGGCTGCTTATGTCACCACCTCTGACCCTACACGGAGCCCATTTCCTTCACAGCATTTGGAAGCTCCTGAAGACAAGTCA
TTTGGCAGTTCATTGATGGAGAGTGAAGTAAACCTGGACCGTTATCAAACAGCTTTAGAAGAAGTATTATCGTGGCTTCTTTCTGCTGAG
GACACATTGCAAGCACAAGGAGAGATTTCTAATGATGTGGAAGTGGTGAAAGACCAGTTTCATACTCATGAGGGGTACATGATGGATTTG
ACAGCCCATCAGGGCCGGGTTGGTAATATTCTACAATTGGGAAGTAAGCTGATTGGAACAGGAAAATTATCAGAAGATGAAGAAACTGAA
GTACAAGAGCAGATGAATCTCCTAAATTCAAGATGGGAATGCCTCAGGGTAGCTAGCATGGAAAAACAAAGCAATTTACATAGAGTTTTA
ATGGATCTCCAGAATCAGAAACTGAAAGAGTTGAATGACTGGCTAACAAAAACAGAAGAAAGAACAAGGAAAATGGAGGAAGAGCCTCTT
GGACCTGATCTTGAAGACCTAAAACGCCAAGTACAACAACATAAGGTGCTTCAAGAAGATCTAGAACAAGAACAAGTCAGGGTCAATTCT
CTCACTCACATGGTGGTGGTAGTTGATGAATCTAGTGGAGATCACGCAACTGCTGCTTTGGAAGAACAACTTAAGGTATTGGGAGATCGA
TGGGCAAACATCTGTAGATGGACAGAAGACCGCTGGGTTCTTTTACAAGACATCCTTCTCAAATGGCAACGTCTTACTGAAGAACAGTGC
CTTTTTAGTGCATGGCTTTCAGAAAAAGAAGATGCAGTGAACAAGATTCACACAACTGGCTTTAAAGATCAAAATGAAATGTTATCAAGT
CTTCAAAAACTGGCCGTTTTAAAAGCGGATCTAGAAAAGAAAAAGCAATCCATGGGCAAACTGTATTCACTCAAACAAGATCTTCTTTCA
ACACTGAAGAATAAGTCAGTGACCCAGAAGACGGAAGCATGGCTGGATAACTTTGCCCGGTGTTGGGATAATTTAGTCCAAAAACTTGAA
AAGAGTACAGCACAGATTTCACAGGCTGTCACCACCACTCAGCCATCACTAACACAGACAACTGTAATGGAAACAGTAACTACGGTGACC
ACAAGGGAACAGATCCTGGTAAAGCATGCTCAAGAGGAACTTCCACCACCACCTCCCCAAAAGAAGAGGCAGATTACTGTGGATTCTGAA
ATTAGGAAAAGGTTGGATGTTGATATAACTGAACTTCACAGCTGGATTACTCGCTCAGAAGCTGTGTTGCAGAGTCCTGAATTTGCAATC
TTTCGGAAGGAAGGCAACTTCTCAGACTTAAAAGAAAAAGTCAATGTCACTGATATGATGCTTCAGGACAAACCCTATCCTGACTGGGGA
AAATCAGCAAGAGCTTTCTGGAAGAAAGGAAATGTTAGGATCACTTTATTCTGGACAGTTCTTTTTACTCTGACGTCTGTGGTTGTACTT
GTGATTACAACGGACTGGATCAGCTGGGACAAGCTGAATCGGGGATTTTTGCCCAGTGATGAAGTTTCCAGAGCATTCCTTGCTTCTTTT
ATCTTGGTCTTTGACCTTCTTATTGTGATGCAGGACTGGGAATTCCCACATTTCATGGGAGATGTTGATGTAAATCTCCCTGGTTTGCAC
ACCCCTCACATGCAGTTCAAGATTCCTTTCTTCCAGAAAATCTTCAAGGAGGAATATCGTATTCACATAACAGGCAAATGGTTTAACTAT
GGAATTATCTTCCTCGTCTTGATTTTGGATCTTAATATGTGGAAGAACCAAATATTTTATAAACCTCATGAATATGGGCAATATATCGGC
CCGGGGCAGAAGATATATACAGTGAAAGACTCAGAAAGTTTAAAAGATTTGAACAGAACCAAGCTATCCTGGGAATGGAGGTCCAATCAC
ACTAACCCTCGGACTAATAAAACATATGTTGAGGGAGACATGTTCTTACACAGCAGGTTCATAGGAGCCAGTCTTGATGTCAAGTGTCTG
GCCTTTGTTCCAAGCCTGATAGCCTTTGTGTGGTTTGGATTCTTTATTTGGTTCTTTGGACGATTTTTGAAAAATGAGCCACGCATGGAG
AATCAAGACAAAACTTACACTCGCATGAAAAGAAAATCTCCATCAGAACATAGCAAAGACATGGGAATCACTCGAGAAAACACCCAGGCT
TCAGTAGAAGACCCCTTGAATGACCCTTCTTTGGTTTGCATCAGGTCTGACTTCAATGAGATCGTCTACAAGTCTTCCCACCTAACCTCG
GAAAACTTGAGCTCACAGTTGAACGAATCTACTAGTGCAACAGAAGCTGATCAAGACCCAACGACTTCTAAAAGTACACCTACGAACTAG
ACTCGGAGATAGACTTGGAGATAACACAAAAAGCAACCTTGAGTGTAACTTTAAAAATTTAGTCTTTCCTTTTGTATATGTAAGGTTTAC
GTAGTGTTAGGTAAAAATATGAACAATGCCACAACGGTGCTCAACATGCTTTTTCTAGGATTCATTGTTTTCTATTTGTATTATAATACA
CGTGCCTACTGTATACTCAACAGTCCTCTAGAGATTGCTTTTCACAATTGCACAAGCTATTACTGACTTTACAGCATAGTGGAAGATTAG
CTGATGACCCATGTATCTGATGTTCAACCATAGTGGTGCCTTGAGACATTAAACTGTTTTTAACTGTACCAGAAATGAAGTGTGGAACAG
TTACCTAACCTATTTCACATGGGCGTTTTGTATACAACTATTTTGATCTACACTTGATGTCTGAGCAGAAAACAGAAATAGCTAAATGTG
ACTCAGGAAGTATCTCTTGGTTTCTTATTCAGCAGCAGAGTTGGTGACTTTGACAACTGGACTGCAGAGAAACATGGTGATCACCTTTTA
ATTTTTATTGGCTGTCTGCCAAATATAAATACAGATGCAAAATTCAGTAATAGGAGATCCATAACCCAACATGGGTCACTACTCGTGAAA
TGTGACTTTCTCCCACCAGTAATTGAAATGAGGTGATGATACCTAATTATGTTTTCCTAATTAAAGATAAATTGCTACTTGATTAAAAAT
CCTGCCCTTCACCTTTGGGAACAAAGGTTAAGAGACACAGTTGGGCGAACTCTCAAATTTATTGGCATTTACACAAAGTCCCAGACAACC
AAGGAACTGAAGTTTTCATCATATGAGAGCAGCACATCCCACCATTTACAATATTCGTATATCTTTCTGCAAATATGGCTCTGGATAGTG
AAAATTGAAAAACATATGCCAACCCTGAGCAAGGGAACTCCTCAAAAAATCATGCAGCGGAACCTTGTCAGGTAGAGAAGCCGTGCATGA
AAGAATTTGTTTAATGTCTTGTTTTGCGTATGTGTTTTTTGTTTTTGTTTTTTAAGAACTAAATATTGCACATTAATAAATAAGAATTAT

>23243_23243_4_DMD-TMEM117_DMD_chrX_32536125_ENST00000378677_TMEM117_chr12_44605073_ENST00000266534_length(amino acids)=1104AA_BP=760
MSEVSSDEREDVQKKTFTKWVNAQFSKFGKQHIENLFSDLQDGRRLLDLLEGLTGQKLPKEKGSTRVHALNNVNKALRVLQNNNVDLVNI
GSTDIVDGNHKLTLGLIWNIILHWQVKNVMKNIMAGLQQTNSEKILLSWVRQSTRNYPQVNVINFTTSWSDGLALNALIHSHRPDLFDWN
SVVCQQSATQRLEHAFNIARYQLGIEKLLDPEDVDTTYPDKKSILMYITSLFQVLPQQVSIEAIQEVEMLPRPPKVTKEEHFQLHHQMHY
SQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHLEAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAEDTLQA
QGEISNDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIGTGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQN
QKLKELNDWLTKTEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANIC
RWTEDRWVLLQDILLKWQRLTEEQCLFSAWLSEKEDAVNKIHTTGFKDQNEMLSSLQKLAVLKADLEKKKQSMGKLYSLKQDLLSTLKNK
SVTQKTEAWLDNFARCWDNLVQKLEKSTAQISQAVTTTQPSLTQTTVMETVTTVTTREQILVKHAQEELPPPPPQKKRQITVDSEIRKRL
DVDITELHSWITRSEAVLQSPEFAIFRKEGNFSDLKEKVNVTDMMLQDKPYPDWGKSARAFWKKGNVRITLFWTVLFTLTSVVVLVITTD
WISWDKLNRGFLPSDEVSRAFLASFILVFDLLIVMQDWEFPHFMGDVDVNLPGLHTPHMQFKIPFFQKIFKEEYRIHITGKWFNYGIIFL
VLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWEWRSNHTNPRTNKTYVEGDMFLHSRFIGASLDVKCLAFVPS
LIAFVWFGFFIWFFGRFLKNEPRMENQDKTYTRMKRKSPSEHSKDMGITRENTQASVEDPLNDPSLVCIRSDFNEIVYKSSHLTSENLSS

--------------------------------------------------------------
>23243_23243_5_DMD-TMEM117_DMD_chrX_32536125_ENST00000378677_TMEM117_chr12_44605073_ENST00000536799_length(transcript)=3510nt_BP=2475nt
GTGCAAAAAGATTGTGTGTTTGTCTGCTTTTGTGAGGCTGGTCAGAGATTCTGTGCCTGCTTTATCTGTGCTTGGCTATGACTCTACCTC
CAGGTTTACCATACCCCATAGAATGTGTAAGAGAAAAGTACCAACAGGGAAATCAGCAAAAAGCTTTCCTATGAAGGTGTGTAGCCAGCC
TCCGCAGAATTTGAAATGTCTGAGGTCTCATCTGATGAAAGAGAAGATGTTCAAAAGAAAACATTCACAAAATGGGTAAATGCACAATTT
TCTAAGTTTGGGAAGCAGCATATTGAGAACCTCTTCAGTGACCTACAGGATGGGAGGCGCCTCCTAGACCTCCTCGAAGGCCTGACAGGG
CAAAAACTGCCAAAAGAAAAAGGATCCACAAGAGTTCATGCCCTGAACAATGTCAACAAGGCACTGCGGGTTTTGCAGAACAATAATGTT
GATTTAGTGAATATTGGAAGTACTGACATCGTAGATGGAAATCATAAACTGACTCTTGGTTTGATTTGGAATATAATCCTCCACTGGCAG
GTCAAAAATGTAATGAAAAATATCATGGCTGGATTGCAACAAACCAACAGTGAAAAGATTCTCCTGAGCTGGGTCCGACAATCAACTCGT
AATTATCCACAGGTTAATGTAATCAACTTCACCACCAGCTGGTCTGATGGCCTGGCTTTGAATGCTCTCATCCATAGTCATAGGCCAGAC
CTATTTGACTGGAATAGTGTGGTTTGCCAGCAGTCAGCCACACAACGACTGGAACATGCATTCAACATCGCCAGATATCAATTAGGCATA
GAGAAACTACTCGATCCTGAAGATGTTGATACCACCTATCCAGATAAGAAGTCCATCTTAATGTACATCACATCACTCTTCCAAGTTTTG
CCTCAACAAGTGAGCATTGAAGCCATCCAGGAAGTGGAAATGTTGCCAAGGCCACCTAAAGTGACTAAAGAAGAACATTTTCAGTTACAT
CATCAAATGCACTATTCTCAACAGATCACGGTCAGTCTAGCACAGGGATATGAGAGAACTTCTTCCCCTAAGCCTCGATTCAAGAGCTAT
GCCTACACACAGGCTGCTTATGTCACCACCTCTGACCCTACACGGAGCCCATTTCCTTCACAGCATTTGGAAGCTCCTGAAGACAAGTCA
TTTGGCAGTTCATTGATGGAGAGTGAAGTAAACCTGGACCGTTATCAAACAGCTTTAGAAGAAGTATTATCGTGGCTTCTTTCTGCTGAG
GACACATTGCAAGCACAAGGAGAGATTTCTAATGATGTGGAAGTGGTGAAAGACCAGTTTCATACTCATGAGGGGTACATGATGGATTTG
ACAGCCCATCAGGGCCGGGTTGGTAATATTCTACAATTGGGAAGTAAGCTGATTGGAACAGGAAAATTATCAGAAGATGAAGAAACTGAA
GTACAAGAGCAGATGAATCTCCTAAATTCAAGATGGGAATGCCTCAGGGTAGCTAGCATGGAAAAACAAAGCAATTTACATAGAGTTTTA
ATGGATCTCCAGAATCAGAAACTGAAAGAGTTGAATGACTGGCTAACAAAAACAGAAGAAAGAACAAGGAAAATGGAGGAAGAGCCTCTT
GGACCTGATCTTGAAGACCTAAAACGCCAAGTACAACAACATAAGGTGCTTCAAGAAGATCTAGAACAAGAACAAGTCAGGGTCAATTCT
CTCACTCACATGGTGGTGGTAGTTGATGAATCTAGTGGAGATCACGCAACTGCTGCTTTGGAAGAACAACTTAAGGTATTGGGAGATCGA
TGGGCAAACATCTGTAGATGGACAGAAGACCGCTGGGTTCTTTTACAAGACATCCTTCTCAAATGGCAACGTCTTACTGAAGAACAGTGC
CTTTTTAGTGCATGGCTTTCAGAAAAAGAAGATGCAGTGAACAAGATTCACACAACTGGCTTTAAAGATCAAAATGAAATGTTATCAAGT
CTTCAAAAACTGGCCGTTTTAAAAGCGGATCTAGAAAAGAAAAAGCAATCCATGGGCAAACTGTATTCACTCAAACAAGATCTTCTTTCA
ACACTGAAGAATAAGTCAGTGACCCAGAAGACGGAAGCATGGCTGGATAACTTTGCCCGGTGTTGGGATAATTTAGTCCAAAAACTTGAA
AAGAGTACAGCACAGATTTCACAGGCTGTCACCACCACTCAGCCATCACTAACACAGACAACTGTAATGGAAACAGTAACTACGGTGACC
ACAAGGGAACAGATCCTGGTAAAGCATGCTCAAGAGGAACTTCCACCACCACCTCCCCAAAAGAAGAGGCAGATTACTGTGGATTCTGAA
ATTAGGAAAAGGTTGGATGTTGATATAACTGAACTTCACAGCTGGATTACTCGCTCAGAAGCTGTGTTGCAGAGTCCTGAATTTGCAATC
TTTCGGAAGGAAGGCAACTTCTCAGACTTAAAAGAAAAAGTCAATGTCACTGATATGATGCTTCAGGACAAACCCTATCCTGACTGGGGA
AAATCAGCAAGAGCTTTCTGGAAGAAAGGAAATGTTAGGATCACTTTATTCTGGACAGTTCTTTTTACTCTGACGTCTGTGGTTGTACTT
GTGATTACAACGGACTGGATCAGCTGGGACAAGCTGAATCGGGGATTTTTGCCCAGTGATGAAGTTTCCAGAGCATTCCTTGCTTCTTTT
ATCTTGGTCTTTGACCTTCTTATTGTGATGCAGGACTGGGAATTCCCACATTTCATGGGAGATGTTGATGTAAATCTCCCTGGTTTGCAC
ACCCCTCACATGCAGTTCAAGATTCCTTTCTTCCAGAAAATCTTCAAGGAGGAATATCGTATTCACATAACAGGCAAATGGTTTAACTAT
GGAATTATCTTCCTCGTCTTGATTTTGGATCTTAATATGTGGAAGAACCAAATATTTTATAAACCTCATGAATATGGGCAATATATCGGC
CCGGGGCAGAAGATATATACAGTGAAAGACTCAGAAAGTTTAAAAGATTTGAACAGAACCAAGCTATCCTGGGAATGGAGGTCCAATCAC
ACTAACCCTCGGACTAATAAAACATATGTTGAGGGAGACATGTTCTTACACAGCAGGTTCATAGGAGCCAGTCTTGATGTCAAGTGTCTG
GCCTTTGTTCCAAGCCTGATAGCCTTTGTGTGGTTTGGATTCTTTATTTGGTTCTTTGGACGATTTTTGAAAAATGAGCCACGCATGGAG
AATCAAGACAAAACTTACACTCGCATGAAAAGAAAATCTCCATCAGAACATAGCAAAGACATGGGAATCACTCGAGAAAACACCCAGGCT
TCAGTAGAAGACCCCTTGAATGACCCTTCTTTGGTTTGCATCAGGTCTGACTTCAATGAGATCGTCTACAAGTCTTCCCACCTAACCTCG
GAAAACTTGAGCTCACAGTTGAACGAATCTACTAGTGCAACAGAAGCTGATCAAGACCCAACGACTTCTAAAAGTACACCTACGAACTAG

>23243_23243_5_DMD-TMEM117_DMD_chrX_32536125_ENST00000378677_TMEM117_chr12_44605073_ENST00000536799_length(amino acids)=1104AA_BP=760
MSEVSSDEREDVQKKTFTKWVNAQFSKFGKQHIENLFSDLQDGRRLLDLLEGLTGQKLPKEKGSTRVHALNNVNKALRVLQNNNVDLVNI
GSTDIVDGNHKLTLGLIWNIILHWQVKNVMKNIMAGLQQTNSEKILLSWVRQSTRNYPQVNVINFTTSWSDGLALNALIHSHRPDLFDWN
SVVCQQSATQRLEHAFNIARYQLGIEKLLDPEDVDTTYPDKKSILMYITSLFQVLPQQVSIEAIQEVEMLPRPPKVTKEEHFQLHHQMHY
SQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHLEAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAEDTLQA
QGEISNDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIGTGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQN
QKLKELNDWLTKTEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANIC
RWTEDRWVLLQDILLKWQRLTEEQCLFSAWLSEKEDAVNKIHTTGFKDQNEMLSSLQKLAVLKADLEKKKQSMGKLYSLKQDLLSTLKNK
SVTQKTEAWLDNFARCWDNLVQKLEKSTAQISQAVTTTQPSLTQTTVMETVTTVTTREQILVKHAQEELPPPPPQKKRQITVDSEIRKRL
DVDITELHSWITRSEAVLQSPEFAIFRKEGNFSDLKEKVNVTDMMLQDKPYPDWGKSARAFWKKGNVRITLFWTVLFTLTSVVVLVITTD
WISWDKLNRGFLPSDEVSRAFLASFILVFDLLIVMQDWEFPHFMGDVDVNLPGLHTPHMQFKIPFFQKIFKEEYRIHITGKWFNYGIIFL
VLILDLNMWKNQIFYKPHEYGQYIGPGQKIYTVKDSESLKDLNRTKLSWEWRSNHTNPRTNKTYVEGDMFLHSRFIGASLDVKCLAFVPS
LIAFVWFGFFIWFFGRFLKNEPRMENQDKTYTRMKRKSPSEHSKDMGITRENTQASVEDPLNDPSLVCIRSDFNEIVYKSSHLTSENLSS

--------------------------------------------------------------
>23243_23243_6_DMD-TMEM117_DMD_chrX_32536125_ENST00000378677_TMEM117_chr12_44605073_ENST00000551577_length(transcript)=4466nt_BP=2475nt
GTGCAAAAAGATTGTGTGTTTGTCTGCTTTTGTGAGGCTGGTCAGAGATTCTGTGCCTGCTTTATCTGTGCTTGGCTATGACTCTACCTC
CAGGTTTACCATACCCCATAGAATGTGTAAGAGAAAAGTACCAACAGGGAAATCAGCAAAAAGCTTTCCTATGAAGGTGTGTAGCCAGCC
TCCGCAGAATTTGAAATGTCTGAGGTCTCATCTGATGAAAGAGAAGATGTTCAAAAGAAAACATTCACAAAATGGGTAAATGCACAATTT
TCTAAGTTTGGGAAGCAGCATATTGAGAACCTCTTCAGTGACCTACAGGATGGGAGGCGCCTCCTAGACCTCCTCGAAGGCCTGACAGGG
CAAAAACTGCCAAAAGAAAAAGGATCCACAAGAGTTCATGCCCTGAACAATGTCAACAAGGCACTGCGGGTTTTGCAGAACAATAATGTT
GATTTAGTGAATATTGGAAGTACTGACATCGTAGATGGAAATCATAAACTGACTCTTGGTTTGATTTGGAATATAATCCTCCACTGGCAG
GTCAAAAATGTAATGAAAAATATCATGGCTGGATTGCAACAAACCAACAGTGAAAAGATTCTCCTGAGCTGGGTCCGACAATCAACTCGT
AATTATCCACAGGTTAATGTAATCAACTTCACCACCAGCTGGTCTGATGGCCTGGCTTTGAATGCTCTCATCCATAGTCATAGGCCAGAC
CTATTTGACTGGAATAGTGTGGTTTGCCAGCAGTCAGCCACACAACGACTGGAACATGCATTCAACATCGCCAGATATCAATTAGGCATA
GAGAAACTACTCGATCCTGAAGATGTTGATACCACCTATCCAGATAAGAAGTCCATCTTAATGTACATCACATCACTCTTCCAAGTTTTG
CCTCAACAAGTGAGCATTGAAGCCATCCAGGAAGTGGAAATGTTGCCAAGGCCACCTAAAGTGACTAAAGAAGAACATTTTCAGTTACAT
CATCAAATGCACTATTCTCAACAGATCACGGTCAGTCTAGCACAGGGATATGAGAGAACTTCTTCCCCTAAGCCTCGATTCAAGAGCTAT
GCCTACACACAGGCTGCTTATGTCACCACCTCTGACCCTACACGGAGCCCATTTCCTTCACAGCATTTGGAAGCTCCTGAAGACAAGTCA
TTTGGCAGTTCATTGATGGAGAGTGAAGTAAACCTGGACCGTTATCAAACAGCTTTAGAAGAAGTATTATCGTGGCTTCTTTCTGCTGAG
GACACATTGCAAGCACAAGGAGAGATTTCTAATGATGTGGAAGTGGTGAAAGACCAGTTTCATACTCATGAGGGGTACATGATGGATTTG
ACAGCCCATCAGGGCCGGGTTGGTAATATTCTACAATTGGGAAGTAAGCTGATTGGAACAGGAAAATTATCAGAAGATGAAGAAACTGAA
GTACAAGAGCAGATGAATCTCCTAAATTCAAGATGGGAATGCCTCAGGGTAGCTAGCATGGAAAAACAAAGCAATTTACATAGAGTTTTA
ATGGATCTCCAGAATCAGAAACTGAAAGAGTTGAATGACTGGCTAACAAAAACAGAAGAAAGAACAAGGAAAATGGAGGAAGAGCCTCTT
GGACCTGATCTTGAAGACCTAAAACGCCAAGTACAACAACATAAGGTGCTTCAAGAAGATCTAGAACAAGAACAAGTCAGGGTCAATTCT
CTCACTCACATGGTGGTGGTAGTTGATGAATCTAGTGGAGATCACGCAACTGCTGCTTTGGAAGAACAACTTAAGGTATTGGGAGATCGA
TGGGCAAACATCTGTAGATGGACAGAAGACCGCTGGGTTCTTTTACAAGACATCCTTCTCAAATGGCAACGTCTTACTGAAGAACAGTGC
CTTTTTAGTGCATGGCTTTCAGAAAAAGAAGATGCAGTGAACAAGATTCACACAACTGGCTTTAAAGATCAAAATGAAATGTTATCAAGT
CTTCAAAAACTGGCCGTTTTAAAAGCGGATCTAGAAAAGAAAAAGCAATCCATGGGCAAACTGTATTCACTCAAACAAGATCTTCTTTCA
ACACTGAAGAATAAGTCAGTGACCCAGAAGACGGAAGCATGGCTGGATAACTTTGCCCGGTGTTGGGATAATTTAGTCCAAAAACTTGAA
AAGAGTACAGCACAGATTTCACAGGCTGTCACCACCACTCAGCCATCACTAACACAGACAACTGTAATGGAAACAGTAACTACGGTGACC
ACAAGGGAACAGATCCTGGTAAAGCATGCTCAAGAGGAACTTCCACCACCACCTCCCCAAAAGAAGAGGCAGATTACTGTGGATTCTGAA
ATTAGGAAAAGGTTGGATGTTGATATAACTGAACTTCACAGCTGGATTACTCGCTCAGAAGCTGTGTTGCAGAGTCCTGAATTTGCAATC
TTTCGGAAGGAAGGCAACTTCTCAGACTTAAAAGAAAAAGTCAATGTCACTGATATGATGCTTCAGGACAAACCCTATCCTGACTGGGGA
AAATCAGCAAGAGCTTTCTGGAAGAAAGGAAATGTTAGGATCACTTTATTCTGGACAGTTCTTTTTACTCTGACGTCTGTGGTTGTACTT
GTGATTACAACGGACTGGATCAGCTGGGACAAGCTGAATCGGGGATTTTTGCCCAGTGATGAAGTTTCCAGAGCATTCCTTGCTTCTTTT
ATCTTGGTCTTTGACCTTCTTATTGTGATGCAGGCAAATGGTTTAACTATGGAATTATCTTCCTCGTCTTGATTTTGGATCTTAATATGT
GGAAGAACCAAATATTTTATAAACCTCATGAATATGGGCAATATATCGGCCCGGGGCAGAAGATATATACAGTGAAAGACTCAGAAAGTT
TAAAAGATTTGAACAGAACCAAGCTATCCTGGGAATGGAGGTCCAATCACACTAACCCTCGGACTAATAAAACATATGTTGAGGGAGACA
TGTTCTTACACAGCAGGTTCATAGGAGCCAGTCTTGATGTCAAGTGTCTGGCCTTTGTTCCAAGCCTGATAGCCTTTGTGTGGTTTGGAT
TCTTTATTTGGTTCTTTGGACGATTTTTGAAAAATGAGCCACGCATGGAGAATCAAGACAAAACTTACACTCGCATGAAAAGAAAATCTC
CATCAGAACATAGCAAAGACATGGGAATCACTCGAGAAAACACCCAGGCTTCAGTAGAAGACCCCTTGAATGACCCTTCTTTGGTTTGCA
TCAGGTCTGACTTCAATGAGATCGTCTACAAGTCTTCCCACCTAACCTCGGAAAACTTGAGCTCACAGTTGAACGAATCTACTAGTGCAA
CAGAAGCTGATCAAGACCCAACGACTTCTAAAAGTACACCTACGAACTAGACTCGGAGATAGACTTGGAGATAACACAAAAAGCAACCTT
GAGTGTAACTTTAAAAATTTAGTCTTTCCTTTTGTATATGTAAGGTTTACGTAGTGTTAGGTAAAAATATGAACAATGCCACAACGGTGC
TCAACATGCTTTTTCTAGGATTCATTGTTTTCTATTTGTATTATAATACACGTGCCTACTGTATACTCAACAGTCCTCTAGAGATTGCTT
TTCACAATTGCACAAGCTATTACTGACTTTACAGCATAGTGGAAGATTAGCTGATGACCCATGTATCTGATGTTCAACCATAGTGGTGCC
TTGAGACATTAAACTGTTTTTAACTGTACCAGAAATGAAGTGTGGAACAGTTACCTAACCTATTTCACATGGGCGTTTTGTATACAACTA
TTTTGATCTACACTTGATGTCTGAGCAGAAAACAGAAATAGCTAAATGTGACTCAGGAAGTATCTCTTGGTTTCTTATTCAGCAGCAGAG
TTGGTGACTTTGACAACTGGACTGCAGAGAAACATGGTGATCACCTTTTAATTTTTATTGGCTGTCTGCCAAATATAAATACAGATGCAA
AATTCAGTAATAGGAGATCCATAACCCAACATGGGTCACTACTCGTGAAATGTGACTTTCTCCCACCAGTAATTGAAATGAGGTGATGAT
ACCTAATTATGTTTTCCTAATTAAAGATAAATTGCTACTTGATTAAAAATCCTGCCCTTCACCTTTGGGAACAAAGGTTAAGAGACACAG
TTGGGCGAACTCTCAAATTTATTGGCATTTACACAAAGTCCCAGACAACCAAGGAACTGAAGTTTTCATCATATGAGAGCAGCACATCCC
ACCATTTACAATATTCGTATATCTTTCTGCAAATATGGCTCTGGATAGTGAAAATTGAAAAACATATGCCAACCCTGAGCAAGGGAACTC
CTCAAAAAATCATGCAGCGGAACCTTGTCAGGTAGAGAAGCCGTGCATGAAAGAATTTGTTTAATGTCTTGTTTTGCGTATGTGTTTTTT

>23243_23243_6_DMD-TMEM117_DMD_chrX_32536125_ENST00000378677_TMEM117_chr12_44605073_ENST00000551577_length(amino acids)=858AA_BP=760
MSEVSSDEREDVQKKTFTKWVNAQFSKFGKQHIENLFSDLQDGRRLLDLLEGLTGQKLPKEKGSTRVHALNNVNKALRVLQNNNVDLVNI
GSTDIVDGNHKLTLGLIWNIILHWQVKNVMKNIMAGLQQTNSEKILLSWVRQSTRNYPQVNVINFTTSWSDGLALNALIHSHRPDLFDWN
SVVCQQSATQRLEHAFNIARYQLGIEKLLDPEDVDTTYPDKKSILMYITSLFQVLPQQVSIEAIQEVEMLPRPPKVTKEEHFQLHHQMHY
SQQITVSLAQGYERTSSPKPRFKSYAYTQAAYVTTSDPTRSPFPSQHLEAPEDKSFGSSLMESEVNLDRYQTALEEVLSWLLSAEDTLQA
QGEISNDVEVVKDQFHTHEGYMMDLTAHQGRVGNILQLGSKLIGTGKLSEDEETEVQEQMNLLNSRWECLRVASMEKQSNLHRVLMDLQN
QKLKELNDWLTKTEERTRKMEEEPLGPDLEDLKRQVQQHKVLQEDLEQEQVRVNSLTHMVVVVDESSGDHATAALEEQLKVLGDRWANIC
RWTEDRWVLLQDILLKWQRLTEEQCLFSAWLSEKEDAVNKIHTTGFKDQNEMLSSLQKLAVLKADLEKKKQSMGKLYSLKQDLLSTLKNK
SVTQKTEAWLDNFARCWDNLVQKLEKSTAQISQAVTTTQPSLTQTTVMETVTTVTTREQILVKHAQEELPPPPPQKKRQITVDSEIRKRL
DVDITELHSWITRSEAVLQSPEFAIFRKEGNFSDLKEKVNVTDMMLQDKPYPDWGKSARAFWKKGNVRITLFWTVLFTLTSVVVLVITTD

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for DMD-TMEM117


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1161415_19130623.0SYNM
HgeneDMDchrX:32536125chr12:44605073ENST00000361471-1163058_34080623.0SYNM
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1131415_19130526.0SYNM
HgeneDMDchrX:32536125chr12:44605073ENST00000378680-1133058_34080526.0SYNM
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1181415_19130618.0SYNM
HgeneDMDchrX:32536125chr12:44605073ENST00000378702-1183058_34080618.0SYNM
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1171415_19130636.0SYNM
HgeneDMDchrX:32536125chr12:44605073ENST00000378723-1173058_34080636.0SYNM


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for DMD-TMEM117


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for DMD-TMEM117


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource