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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:DMKN-NUMBL (FusionGDB2 ID:23252) |
Fusion Gene Summary for DMKN-NUMBL |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: DMKN-NUMBL | Fusion gene ID: 23252 | Hgene | Tgene | Gene symbol | DMKN | NUMBL | Gene ID | 93099 | 9253 |
| Gene name | dermokine | NUMB like endocytic adaptor protein | |
| Synonyms | UNQ729|ZD52F10 | CAG3A|CTG3a|NBL|NUMB-R|NUMBLIKE|NUMBR|TNRC23 | |
| Cytomap | 19q13.12 | 19q13.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | dermokineepidermis-specific secreted protein SK30/SK89 | numb-like proteinnumb homolog-likenumb-related protein | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | Q6E0U4 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000339686, ENST00000392206, ENST00000402589, ENST00000414866, ENST00000418261, ENST00000419602, ENST00000424570, ENST00000429837, ENST00000436012, ENST00000440396, ENST00000443640, ENST00000447113, ENST00000451297, ENST00000458071, ENST00000467637, ENST00000480502, ENST00000488892, ENST00000602781, ENST00000461300, ENST00000462126, ENST00000472252, ENST00000474928, ENST00000492341, ENST00000408915, | ENST00000599594, ENST00000540131, ENST00000598779, ENST00000252891, | |
| Fusion gene scores | * DoF score | 2 X 2 X 2=8 | 8 X 7 X 5=280 |
| # samples | 2 | 8 | |
| ** MAII score | log2(2/8*10)=1.32192809488736 | log2(8/280*10)=-1.8073549220576 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: DMKN [Title/Abstract] AND NUMBL [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | DMKN(36001086)-NUMBL(41192900), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | NUMBL | GO:0019221 | cytokine-mediated signaling pathway | 18299187 |
| Tgene | NUMBL | GO:0019538 | protein metabolic process | 20079715 |
| Fusion gene breakpoints across DMKN (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across NUMBL (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | LUAD | TCGA-55-7995-01A | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
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Fusion Gene ORF analysis for DMKN-NUMBL |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000339686 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-5UTR | ENST00000392206 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-5UTR | ENST00000402589 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-5UTR | ENST00000414866 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-5UTR | ENST00000418261 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-5UTR | ENST00000419602 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-5UTR | ENST00000424570 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-5UTR | ENST00000429837 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-5UTR | ENST00000436012 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-5UTR | ENST00000440396 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-5UTR | ENST00000443640 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-5UTR | ENST00000447113 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-5UTR | ENST00000451297 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-5UTR | ENST00000458071 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-5UTR | ENST00000467637 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-5UTR | ENST00000480502 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-5UTR | ENST00000488892 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-5UTR | ENST00000602781 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000339686 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000339686 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000392206 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000392206 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000402589 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000402589 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000414866 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000414866 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000418261 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000418261 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000419602 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000419602 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000424570 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000424570 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000429837 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000429837 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000436012 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000436012 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000440396 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000440396 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000443640 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000443640 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000447113 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000447113 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000451297 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000451297 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000458071 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000458071 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000467637 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000467637 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000480502 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000480502 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000488892 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000488892 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000602781 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5CDS-intron | ENST00000602781 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-3CDS | ENST00000461300 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-3CDS | ENST00000462126 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-3CDS | ENST00000472252 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-3CDS | ENST00000474928 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-3CDS | ENST00000492341 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-5UTR | ENST00000461300 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-5UTR | ENST00000462126 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-5UTR | ENST00000472252 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-5UTR | ENST00000474928 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-5UTR | ENST00000492341 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-intron | ENST00000461300 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-intron | ENST00000461300 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-intron | ENST00000462126 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-intron | ENST00000462126 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-intron | ENST00000472252 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-intron | ENST00000472252 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-intron | ENST00000474928 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-intron | ENST00000474928 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-intron | ENST00000492341 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| 5UTR-intron | ENST00000492341 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| In-frame | ENST00000339686 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| In-frame | ENST00000392206 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| In-frame | ENST00000402589 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| In-frame | ENST00000414866 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| In-frame | ENST00000418261 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| In-frame | ENST00000419602 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| In-frame | ENST00000424570 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| In-frame | ENST00000429837 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| In-frame | ENST00000436012 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| In-frame | ENST00000440396 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| In-frame | ENST00000443640 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| In-frame | ENST00000447113 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| In-frame | ENST00000451297 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| In-frame | ENST00000458071 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| In-frame | ENST00000467637 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| In-frame | ENST00000480502 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| In-frame | ENST00000488892 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| In-frame | ENST00000602781 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| intron-3CDS | ENST00000408915 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| intron-5UTR | ENST00000408915 | ENST00000599594 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| intron-intron | ENST00000408915 | ENST00000540131 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| intron-intron | ENST00000408915 | ENST00000598779 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000402589 | DMKN | chr19 | 36001086 | - | ENST00000252891 | NUMBL | chr19 | 41192900 | - | 2713 | 130 | 4 | 1935 | 643 |
| ENST00000339686 | DMKN | chr19 | 36001086 | - | ENST00000252891 | NUMBL | chr19 | 41192900 | - | 3747 | 1164 | 18 | 2969 | 983 |
| ENST00000436012 | DMKN | chr19 | 36001086 | - | ENST00000252891 | NUMBL | chr19 | 41192900 | - | 2721 | 138 | 0 | 1943 | 647 |
| ENST00000414866 | DMKN | chr19 | 36001086 | - | ENST00000252891 | NUMBL | chr19 | 41192900 | - | 2752 | 169 | 1 | 1974 | 657 |
| ENST00000480502 | DMKN | chr19 | 36001086 | - | ENST00000252891 | NUMBL | chr19 | 41192900 | - | 2741 | 158 | 20 | 1963 | 647 |
| ENST00000467637 | DMKN | chr19 | 36001086 | - | ENST00000252891 | NUMBL | chr19 | 41192900 | - | 2728 | 145 | 7 | 1950 | 647 |
| ENST00000429837 | DMKN | chr19 | 36001086 | - | ENST00000252891 | NUMBL | chr19 | 41192900 | - | 3393 | 810 | 6 | 2615 | 869 |
| ENST00000419602 | DMKN | chr19 | 36001086 | - | ENST00000252891 | NUMBL | chr19 | 41192900 | - | 3394 | 811 | 7 | 2616 | 869 |
| ENST00000443640 | DMKN | chr19 | 36001086 | - | ENST00000252891 | NUMBL | chr19 | 41192900 | - | 2721 | 138 | 0 | 1943 | 647 |
| ENST00000602781 | DMKN | chr19 | 36001086 | - | ENST00000252891 | NUMBL | chr19 | 41192900 | - | 2710 | 127 | 1 | 1932 | 643 |
| ENST00000488892 | DMKN | chr19 | 36001086 | - | ENST00000252891 | NUMBL | chr19 | 41192900 | - | 2757 | 174 | 6 | 1979 | 657 |
| ENST00000447113 | DMKN | chr19 | 36001086 | - | ENST00000252891 | NUMBL | chr19 | 41192900 | - | 3753 | 1170 | 24 | 2975 | 983 |
| ENST00000392206 | DMKN | chr19 | 36001086 | - | ENST00000252891 | NUMBL | chr19 | 41192900 | - | 2752 | 169 | 1 | 1974 | 657 |
| ENST00000440396 | DMKN | chr19 | 36001086 | - | ENST00000252891 | NUMBL | chr19 | 41192900 | - | 3753 | 1170 | 24 | 2975 | 983 |
| ENST00000458071 | DMKN | chr19 | 36001086 | - | ENST00000252891 | NUMBL | chr19 | 41192900 | - | 2717 | 134 | 8 | 1939 | 643 |
| ENST00000418261 | DMKN | chr19 | 36001086 | - | ENST00000252891 | NUMBL | chr19 | 41192900 | - | 3576 | 993 | 6 | 2798 | 930 |
| ENST00000424570 | DMKN | chr19 | 36001086 | - | ENST00000252891 | NUMBL | chr19 | 41192900 | - | 3576 | 993 | 6 | 2798 | 930 |
| ENST00000451297 | DMKN | chr19 | 36001086 | - | ENST00000252891 | NUMBL | chr19 | 41192900 | - | 3570 | 987 | 0 | 2792 | 930 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000402589 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - | 0.06949878 | 0.9305012 |
| ENST00000339686 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - | 0.011832167 | 0.9881678 |
| ENST00000436012 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - | 0.06862074 | 0.93137926 |
| ENST00000414866 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - | 0.067479745 | 0.9325203 |
| ENST00000480502 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - | 0.066841185 | 0.9331588 |
| ENST00000467637 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - | 0.068017036 | 0.93198293 |
| ENST00000429837 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - | 0.013558948 | 0.9864411 |
| ENST00000419602 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - | 0.013563138 | 0.9864369 |
| ENST00000443640 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - | 0.06862074 | 0.93137926 |
| ENST00000602781 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - | 0.06985176 | 0.93014824 |
| ENST00000488892 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - | 0.06787168 | 0.93212837 |
| ENST00000447113 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - | 0.011688222 | 0.9883118 |
| ENST00000392206 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - | 0.067479745 | 0.9325203 |
| ENST00000440396 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - | 0.011688222 | 0.9883118 |
| ENST00000458071 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - | 0.06887106 | 0.931129 |
| ENST00000418261 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - | 0.013218381 | 0.98678166 |
| ENST00000424570 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - | 0.013218381 | 0.98678166 |
| ENST00000451297 | ENST00000252891 | DMKN | chr19 | 36001086 | - | NUMBL | chr19 | 41192900 | - | 0.013046818 | 0.98695326 |
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Fusion Genomic Features for DMKN-NUMBL |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for DMKN-NUMBL |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:36001086/chr19:41192900) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| DMKN | . |
| FUNCTION: May act as a soluble regulator of keratinocyte differentiation. {ECO:0000305}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | NUMBL | chr19:36001086 | chr19:41192900 | ENST00000252891 | 0 | 10 | 427_446 | 8 | 610.0 | Compositional bias | Note=Poly-Gln | |
| Tgene | NUMBL | chr19:36001086 | chr19:41192900 | ENST00000540131 | 0 | 9 | 427_446 | 0 | 569.0 | Compositional bias | Note=Poly-Gln | |
| Tgene | NUMBL | chr19:36001086 | chr19:41192900 | ENST00000598779 | 0 | 9 | 427_446 | 0 | 569.0 | Compositional bias | Note=Poly-Gln | |
| Tgene | NUMBL | chr19:36001086 | chr19:41192900 | ENST00000252891 | 0 | 10 | 74_223 | 8 | 610.0 | Domain | PID | |
| Tgene | NUMBL | chr19:36001086 | chr19:41192900 | ENST00000540131 | 0 | 9 | 74_223 | 0 | 569.0 | Domain | PID | |
| Tgene | NUMBL | chr19:36001086 | chr19:41192900 | ENST00000598779 | 0 | 9 | 74_223 | 0 | 569.0 | Domain | PID |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | DMKN | chr19:36001086 | chr19:41192900 | ENST00000339686 | - | 6 | 16 | 17_344 | 329 | 331.3333333333333 | Compositional bias | Note=Gly-rich |
| Hgene | DMKN | chr19:36001086 | chr19:41192900 | ENST00000408915 | - | 1 | 6 | 17_344 | 0 | 167.66666666666666 | Compositional bias | Note=Gly-rich |
| Hgene | DMKN | chr19:36001086 | chr19:41192900 | ENST00000414866 | - | 2 | 12 | 17_344 | 42 | 234.33333333333334 | Compositional bias | Note=Gly-rich |
| Hgene | DMKN | chr19:36001086 | chr19:41192900 | ENST00000418261 | - | 6 | 10 | 17_344 | 329 | 387.0 | Compositional bias | Note=Gly-rich |
| Hgene | DMKN | chr19:36001086 | chr19:41192900 | ENST00000419602 | - | 5 | 18 | 17_344 | 268 | 301.0 | Compositional bias | Note=Gly-rich |
| Hgene | DMKN | chr19:36001086 | chr19:41192900 | ENST00000424570 | - | 6 | 11 | 17_344 | 329 | 399.0 | Compositional bias | Note=Gly-rich |
| Hgene | DMKN | chr19:36001086 | chr19:41192900 | ENST00000429837 | - | 5 | 17 | 17_344 | 268 | 285.3333333333333 | Compositional bias | Note=Gly-rich |
| Hgene | DMKN | chr19:36001086 | chr19:41192900 | ENST00000447113 | - | 6 | 13 | 17_344 | 329 | 437.0 | Compositional bias | Note=Gly-rich |
| Hgene | DMKN | chr19:36001086 | chr19:41192900 | ENST00000451297 | - | 6 | 9 | 17_344 | 329 | 370.0 | Compositional bias | Note=Gly-rich |
| Hgene | DMKN | chr19:36001086 | chr19:41192900 | ENST00000472252 | - | 2 | 12 | 17_344 | 0 | 113.33333333333333 | Compositional bias | Note=Gly-rich |
| Hgene | DMKN | chr19:36001086 | chr19:41192900 | ENST00000492341 | - | 1 | 9 | 17_344 | 0 | 124.0 | Compositional bias | Note=Gly-rich |
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Fusion Gene Sequence for DMKN-NUMBL |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >23252_23252_1_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000339686_NUMBL_chr19_41192900_ENST00000252891_length(transcript)=3747nt_BP=1164nt TCTGAGAAGCCCAGGCAGTTGAGGACAGGAGAGAGAAGGCTGCAGACCCAGAGGGAGGGAGGACAGGGAGTCGGAAGGAGGAGGACAGAG GAGGGCACAGAGACGCAGAGCAAGGGCGGCAAGGAGGAGACCCTGGTGGGAGGAAGACACTCTGGAGAGAGAGGGGGCTGGGCAGAGATG AAGTTCCAGGGGCCCCTGGCCTGCCTCCTGCTGGCCCTCTGCCTGGGCAGTGGGGAGGCTGGCCCCCTGCAGAGCGGAGAGGAAAGCACT GGGACAAATATTGGGGAGGCCCTTGGACATGGCCTGGGAGACGCCCTGAGCGAAGGGGTGGGAAAGGCCATTGGCAAAGAGGCCGGAGGG GCAGCTGGCTCTAAAGTCAGTGAGGCCCTTGGCCAAGGGACCAGAGAAGCAGTTGGCACTGGAGTCAGGCAGGTTCCAGGCTTTGGCGTA GCAGATGCTTTGGGCAACAGGGTCGGGGAAGCAGCCCATGCTCTGGGAAACACTGGGCACGAGATTGGCAGACAGGCAGAAGATGTCATT CGACACGGAGCAGATGCTGTCCGCGGCTCCTGGCAGGGGGTGCCTGGCCACAATGGTGCTTGGGAAACTTCTGGAGGCCATGGCATCTTT GGCTCTCAAGGTGGCCTTGGAGGCCAGGGCCAGGGCAATCCTGGAGGTCTGGGGACTCCGTGGGTCCACGGATACCCCGGAAACTCAGCA GGCAGCTTTGGAATGAATCCTCAGGGAGCTCCCTGGGGTCAAGGAGGCAATGGAGGGCCACCAAACTTTGGGACCAACACTCAGGGAGCT GTGGCCCAGCCTGGCTATGGTTCAGTGAGAGCCAGCAACCAGAATGAAGGGTGCACGAATCCCCCACCATCTGGCTCAGGTGGAGGCTCC AGCAACTCTGGGGGAGGCAGCGGCTCACAGTCGGGCAGCAGTGGCAGTGGCAGCAATGGTGACAACAACAATGGCAGCAGCAGTGGTGGC AGCAGCAGTGGCAGCAGCAGTGGCGGCAGCAGTGGCGGCAGCAGTGGTGGCAGCAGTGGCAACAGTGGTGGCAGCAGAGGTGACAGCGGC AGTGAGTCCTCCTGGGGATCCAGCACCGGCTCCTCCTCCGGCAACCACGGTGGGAGCGGCGGAGGAAATGGACATAAACCCGGGGGCGGA CCCCGGAGGCCTGAGCGGCACCTGCCCCCAGCCCCCTGTGGGGCCCCGGGGCCCCCAGAAACCTGCAGGACGGAGCCAGACGGGGCGGGC ACCATGAACAAGTTACGGCAGAGCCTGCGGCGGAGGAAGCCAGCCTACGTGCCCGAGGCGTCGCGCCCGCACCAGTGGCAGGCAGACGAG GACGCGGTGCGGAAGGGCACGTGCAGCTTCCCGGTCAGGTACCTGGGTCACGTGGAGGTAGAGGAGTCCCGGGGAATGCACGTGTGTGAA GATGCGGTGAAGAAGCTGAAGGCGATGGGCCGAAAGTCCGTGAAGTCTGTCCTGTGGGTGTCAGCCGATGGGCTCCGAGTGGTGGACGAC AAAACCAAGGATCTTCTGGTCGACCAGACCATCGAAAAGGTCTCCTTTTGTGCTCCTGACCGCAACCTGGACAAGGCTTTCTCCTATATC TGTCGTGACGGGACTACCCGCCGCTGGATCTGCCACTGTTTTCTGGCACTGAAGGACTCCGGCGAGAGGCTGAGCCACGCTGTGGGCTGT GCTTTTGCCGCCTGCCTGGAGCGAAAACAGCGACGGGAGAAGGAATGTGGGGTCACGGCCGCCTTCGATGCCAGCCGCACCAGCTTCGCC CGCGAGGGCTCCTTCCGCCTGTCTGGGGGTGGGCGGCCTGCTGAGCGAGAGGCCCCGGACAAGAAGAAAGCAGAGGCAGCAGCTGCCCCC ACTGTGGCTCCTGGCCCTGCCCAGCCTGGGCACGTGTCCCCGACACCAGCCACCACATCCCCTGGTGAGAAGGGTGAGGCAGGCACCCCT GTGGCTGCAGGCACCACTGCGGCCGCCATCCCCCGGCGCCATGCACCCCTGGAGCAGCTGGTTCGCCAGGGCTCCTTCCGTGGGTTCCCA GCACTCAGCCAGAAGAACTCGCCTTTCAAACGGCAGCTGAGCCTACGGCTGAATGAGCTGCCATCCACGCTGCAGCGCCGCACTGACTTC CAGGTGAAGGGCACAGTGCCTGAGATGGAGCCTCCTGGTGCCGGCGACAGTGACAGCATCAACGCTCTGTGCACACAGATCAGTTCATCT TTTGCCAGTGCTGGAGCGCCAGCACCAGGGCCACCACCTGCCACAACAGGGACTTCTGCCTGGGGTGAGCCCTCCGTGCCCCCTGCAGCT GCCTTCCAGCCTGGGCACAAGCGGACACCTTCAGAGGCTGAGCGATGGCTGGAGGAGGTGTCACAGGTGGCCAAGGCCCAGCAGCAGCAG CAGCAGCAACAGCAACAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAAGCAGCCTCAGTGGCCCCAGTGCCCACCATGCCTCCTGCCCTG CAGCCTTTCCCCGCCCCCGTGGGGCCCTTTGACGCTGCACCTGCCCAAGTGGCCGTGTTCCTGCCACCCCCACACATGCAGCCCCCTTTT GTGCCCGCCTACCCGGGCTTGGGCTACCCACCGATGCCCCGGGTGCCCGTGGTGGGCATCACACCCTCACAGATGGTGGCAAACGCCTTC TGCTCAGCCGCCCAGCTCCAGCCTCAGCCTGCCACTCTGCTTGGGAAAGCTGGGGCCTTCCCGCCCCCTGCCATACCCAGTGCCCCTGGG AGCCAGGCCCGCCCTCGCCCCAATGGGGCCCCCTGGCCCCCTGAGCCAGCGCCTGCCCCAGCTCCAGAGTTGGACCCCTTTGAGGCCCAG TGGGCGGCATTAGAAGGCAAAGCCACTGTAGAGAAACCCTCCAACCCCTTTTCTGGCGACCTGCAAAAGACATTCGAGATTGAACTGTAG CCCGAGCCGCCCCACCCACTCCATCATCTCCAGGTGCCCCACGCCTGGGGGTGGAGGCACAACCTCTCCCCTAACCCTGCTCCCTGGGGC TGCGCCCCTCAACACCCTCTCAACACCCCCCTCCCTCAACCACCCCGACAACCACTACAGAACCAACATTGTGACGCCCAGGTTGCAACA GGATGGAATTCAGGGACGGACCCAGCCTGGCTAAGGGAACCATTTCACTGCCGGACTTAGGCTGGCAATGCCCCCTTCCCCAACCCCAGA CACAGGGGTTGGCCACAATCCCACTGAATGCCCTTGGTTCACACTCCATTTCCCAGTTTCTGTTGACCCCCACCTTCCAGTGTTGGACAG GATGGAGGGGGGACACTTGCTTAGGGGCTCTCCTGGGCCCCACACCAGTGCCCACCCCAAATCTGGTCGTCTCCTCCCCCCATGCACAGC ACAAGCTAAGGGCTGCCCTCTGCCCACACGCTGCGTTCACTGCCAATGCTGTACTCACCTCCATCACCCTCCAACTTTGGGGCCCATGTC TTCCTTGGGCCAAGGTCTCATGGGGGCTAGGGCCAAGTTGGGGGCCCAGGAGGCGGGGAGGGAGGAGGAGGAGAAGATGCGCAGTTACCT CATGTCGGTGCCCGCTGGGGAGGGGTCCGGGAAGAAGGGGAAGGGGTGCCTGGCGGGTACTTTTCTATCTTTTATTTCCAGATTTTTTTT >23252_23252_1_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000339686_NUMBL_chr19_41192900_ENST00000252891_length(amino acids)=983AA_BP=382 MRTGERRLQTQREGGQGVGRRRTEEGTETQSKGGKEETLVGGRHSGERGGWAEMKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGE ALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGVADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADA VRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGY GSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG SSTGSSSGNHGGSGGGNGHKPGGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKG TCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTT RRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAPDKKKAEAAAAPTVAPGP AQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTV PEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQ QQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQL -------------------------------------------------------------- >23252_23252_2_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000392206_NUMBL_chr19_41192900_ENST00000252891_length(transcript)=2752nt_BP=169nt ATTGCGTAGTTCCGAATACCCTCGGCCACACCTGGCCTTCTCCATGCTCGGAATAACTTCCTGCAGCGACCAACAGGCTAAAGAGGGGGA AGGTCTGGAGGGATCCAGCACCGGCTCCTCCTCCGGCAACCACGGTGGGAGCGGCGGAGGAAATGGACATAAACCCGGGGGCGGACCCCG GAGGCCTGAGCGGCACCTGCCCCCAGCCCCCTGTGGGGCCCCGGGGCCCCCAGAAACCTGCAGGACGGAGCCAGACGGGGCGGGCACCAT GAACAAGTTACGGCAGAGCCTGCGGCGGAGGAAGCCAGCCTACGTGCCCGAGGCGTCGCGCCCGCACCAGTGGCAGGCAGACGAGGACGC GGTGCGGAAGGGCACGTGCAGCTTCCCGGTCAGGTACCTGGGTCACGTGGAGGTAGAGGAGTCCCGGGGAATGCACGTGTGTGAAGATGC GGTGAAGAAGCTGAAGGCGATGGGCCGAAAGTCCGTGAAGTCTGTCCTGTGGGTGTCAGCCGATGGGCTCCGAGTGGTGGACGACAAAAC CAAGGATCTTCTGGTCGACCAGACCATCGAAAAGGTCTCCTTTTGTGCTCCTGACCGCAACCTGGACAAGGCTTTCTCCTATATCTGTCG TGACGGGACTACCCGCCGCTGGATCTGCCACTGTTTTCTGGCACTGAAGGACTCCGGCGAGAGGCTGAGCCACGCTGTGGGCTGTGCTTT TGCCGCCTGCCTGGAGCGAAAACAGCGACGGGAGAAGGAATGTGGGGTCACGGCCGCCTTCGATGCCAGCCGCACCAGCTTCGCCCGCGA GGGCTCCTTCCGCCTGTCTGGGGGTGGGCGGCCTGCTGAGCGAGAGGCCCCGGACAAGAAGAAAGCAGAGGCAGCAGCTGCCCCCACTGT GGCTCCTGGCCCTGCCCAGCCTGGGCACGTGTCCCCGACACCAGCCACCACATCCCCTGGTGAGAAGGGTGAGGCAGGCACCCCTGTGGC TGCAGGCACCACTGCGGCCGCCATCCCCCGGCGCCATGCACCCCTGGAGCAGCTGGTTCGCCAGGGCTCCTTCCGTGGGTTCCCAGCACT CAGCCAGAAGAACTCGCCTTTCAAACGGCAGCTGAGCCTACGGCTGAATGAGCTGCCATCCACGCTGCAGCGCCGCACTGACTTCCAGGT GAAGGGCACAGTGCCTGAGATGGAGCCTCCTGGTGCCGGCGACAGTGACAGCATCAACGCTCTGTGCACACAGATCAGTTCATCTTTTGC CAGTGCTGGAGCGCCAGCACCAGGGCCACCACCTGCCACAACAGGGACTTCTGCCTGGGGTGAGCCCTCCGTGCCCCCTGCAGCTGCCTT CCAGCCTGGGCACAAGCGGACACCTTCAGAGGCTGAGCGATGGCTGGAGGAGGTGTCACAGGTGGCCAAGGCCCAGCAGCAGCAGCAGCA GCAACAGCAACAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAAGCAGCCTCAGTGGCCCCAGTGCCCACCATGCCTCCTGCCCTGCAGCC TTTCCCCGCCCCCGTGGGGCCCTTTGACGCTGCACCTGCCCAAGTGGCCGTGTTCCTGCCACCCCCACACATGCAGCCCCCTTTTGTGCC CGCCTACCCGGGCTTGGGCTACCCACCGATGCCCCGGGTGCCCGTGGTGGGCATCACACCCTCACAGATGGTGGCAAACGCCTTCTGCTC AGCCGCCCAGCTCCAGCCTCAGCCTGCCACTCTGCTTGGGAAAGCTGGGGCCTTCCCGCCCCCTGCCATACCCAGTGCCCCTGGGAGCCA GGCCCGCCCTCGCCCCAATGGGGCCCCCTGGCCCCCTGAGCCAGCGCCTGCCCCAGCTCCAGAGTTGGACCCCTTTGAGGCCCAGTGGGC GGCATTAGAAGGCAAAGCCACTGTAGAGAAACCCTCCAACCCCTTTTCTGGCGACCTGCAAAAGACATTCGAGATTGAACTGTAGCCCGA GCCGCCCCACCCACTCCATCATCTCCAGGTGCCCCACGCCTGGGGGTGGAGGCACAACCTCTCCCCTAACCCTGCTCCCTGGGGCTGCGC CCCTCAACACCCTCTCAACACCCCCCTCCCTCAACCACCCCGACAACCACTACAGAACCAACATTGTGACGCCCAGGTTGCAACAGGATG GAATTCAGGGACGGACCCAGCCTGGCTAAGGGAACCATTTCACTGCCGGACTTAGGCTGGCAATGCCCCCTTCCCCAACCCCAGACACAG GGGTTGGCCACAATCCCACTGAATGCCCTTGGTTCACACTCCATTTCCCAGTTTCTGTTGACCCCCACCTTCCAGTGTTGGACAGGATGG AGGGGGGACACTTGCTTAGGGGCTCTCCTGGGCCCCACACCAGTGCCCACCCCAAATCTGGTCGTCTCCTCCCCCCATGCACAGCACAAG CTAAGGGCTGCCCTCTGCCCACACGCTGCGTTCACTGCCAATGCTGTACTCACCTCCATCACCCTCCAACTTTGGGGCCCATGTCTTCCT TGGGCCAAGGTCTCATGGGGGCTAGGGCCAAGTTGGGGGCCCAGGAGGCGGGGAGGGAGGAGGAGGAGAAGATGCGCAGTTACCTCATGT CGGTGCCCGCTGGGGAGGGGTCCGGGAAGAAGGGGAAGGGGTGCCTGGCGGGTACTTTTCTATCTTTTATTTCCAGATTTTTTTTGTATC >23252_23252_2_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000392206_NUMBL_chr19_41192900_ENST00000252891_length(amino acids)=657AA_BP=56 LRSSEYPRPHLAFSMLGITSCSDQQAKEGEGLEGSSTGSSSGNHGGSGGGNGHKPGGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTM NKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDKT KDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFARE GSFRLSGGGRPAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPAL SQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAF QPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVP AYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWA -------------------------------------------------------------- >23252_23252_3_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000402589_NUMBL_chr19_41192900_ENST00000252891_length(transcript)=2713nt_BP=130nt CTCCATGCTCGGAATAACTTCCTGCAGCGACCAACAGGCTAAAGAGGGGGAAGGTCTGGAGGGATCCAGCACCGGCTCCTCCTCCGGCAA CCACGGTGGGAGCGGCGGAGGAAATGGACATAAACCCGGGGGCGGACCCCGGAGGCCTGAGCGGCACCTGCCCCCAGCCCCCTGTGGGGC CCCGGGGCCCCCAGAAACCTGCAGGACGGAGCCAGACGGGGCGGGCACCATGAACAAGTTACGGCAGAGCCTGCGGCGGAGGAAGCCAGC CTACGTGCCCGAGGCGTCGCGCCCGCACCAGTGGCAGGCAGACGAGGACGCGGTGCGGAAGGGCACGTGCAGCTTCCCGGTCAGGTACCT GGGTCACGTGGAGGTAGAGGAGTCCCGGGGAATGCACGTGTGTGAAGATGCGGTGAAGAAGCTGAAGGCGATGGGCCGAAAGTCCGTGAA GTCTGTCCTGTGGGTGTCAGCCGATGGGCTCCGAGTGGTGGACGACAAAACCAAGGATCTTCTGGTCGACCAGACCATCGAAAAGGTCTC CTTTTGTGCTCCTGACCGCAACCTGGACAAGGCTTTCTCCTATATCTGTCGTGACGGGACTACCCGCCGCTGGATCTGCCACTGTTTTCT GGCACTGAAGGACTCCGGCGAGAGGCTGAGCCACGCTGTGGGCTGTGCTTTTGCCGCCTGCCTGGAGCGAAAACAGCGACGGGAGAAGGA ATGTGGGGTCACGGCCGCCTTCGATGCCAGCCGCACCAGCTTCGCCCGCGAGGGCTCCTTCCGCCTGTCTGGGGGTGGGCGGCCTGCTGA GCGAGAGGCCCCGGACAAGAAGAAAGCAGAGGCAGCAGCTGCCCCCACTGTGGCTCCTGGCCCTGCCCAGCCTGGGCACGTGTCCCCGAC ACCAGCCACCACATCCCCTGGTGAGAAGGGTGAGGCAGGCACCCCTGTGGCTGCAGGCACCACTGCGGCCGCCATCCCCCGGCGCCATGC ACCCCTGGAGCAGCTGGTTCGCCAGGGCTCCTTCCGTGGGTTCCCAGCACTCAGCCAGAAGAACTCGCCTTTCAAACGGCAGCTGAGCCT ACGGCTGAATGAGCTGCCATCCACGCTGCAGCGCCGCACTGACTTCCAGGTGAAGGGCACAGTGCCTGAGATGGAGCCTCCTGGTGCCGG CGACAGTGACAGCATCAACGCTCTGTGCACACAGATCAGTTCATCTTTTGCCAGTGCTGGAGCGCCAGCACCAGGGCCACCACCTGCCAC AACAGGGACTTCTGCCTGGGGTGAGCCCTCCGTGCCCCCTGCAGCTGCCTTCCAGCCTGGGCACAAGCGGACACCTTCAGAGGCTGAGCG ATGGCTGGAGGAGGTGTCACAGGTGGCCAAGGCCCAGCAGCAGCAGCAGCAGCAACAGCAACAGCAGCAGCAGCAGCAGCAGCAACAGCA GCAAGCAGCCTCAGTGGCCCCAGTGCCCACCATGCCTCCTGCCCTGCAGCCTTTCCCCGCCCCCGTGGGGCCCTTTGACGCTGCACCTGC CCAAGTGGCCGTGTTCCTGCCACCCCCACACATGCAGCCCCCTTTTGTGCCCGCCTACCCGGGCTTGGGCTACCCACCGATGCCCCGGGT GCCCGTGGTGGGCATCACACCCTCACAGATGGTGGCAAACGCCTTCTGCTCAGCCGCCCAGCTCCAGCCTCAGCCTGCCACTCTGCTTGG GAAAGCTGGGGCCTTCCCGCCCCCTGCCATACCCAGTGCCCCTGGGAGCCAGGCCCGCCCTCGCCCCAATGGGGCCCCCTGGCCCCCTGA GCCAGCGCCTGCCCCAGCTCCAGAGTTGGACCCCTTTGAGGCCCAGTGGGCGGCATTAGAAGGCAAAGCCACTGTAGAGAAACCCTCCAA CCCCTTTTCTGGCGACCTGCAAAAGACATTCGAGATTGAACTGTAGCCCGAGCCGCCCCACCCACTCCATCATCTCCAGGTGCCCCACGC CTGGGGGTGGAGGCACAACCTCTCCCCTAACCCTGCTCCCTGGGGCTGCGCCCCTCAACACCCTCTCAACACCCCCCTCCCTCAACCACC CCGACAACCACTACAGAACCAACATTGTGACGCCCAGGTTGCAACAGGATGGAATTCAGGGACGGACCCAGCCTGGCTAAGGGAACCATT TCACTGCCGGACTTAGGCTGGCAATGCCCCCTTCCCCAACCCCAGACACAGGGGTTGGCCACAATCCCACTGAATGCCCTTGGTTCACAC TCCATTTCCCAGTTTCTGTTGACCCCCACCTTCCAGTGTTGGACAGGATGGAGGGGGGACACTTGCTTAGGGGCTCTCCTGGGCCCCACA CCAGTGCCCACCCCAAATCTGGTCGTCTCCTCCCCCCATGCACAGCACAAGCTAAGGGCTGCCCTCTGCCCACACGCTGCGTTCACTGCC AATGCTGTACTCACCTCCATCACCCTCCAACTTTGGGGCCCATGTCTTCCTTGGGCCAAGGTCTCATGGGGGCTAGGGCCAAGTTGGGGG CCCAGGAGGCGGGGAGGGAGGAGGAGGAGAAGATGCGCAGTTACCTCATGTCGGTGCCCGCTGGGGAGGGGTCCGGGAAGAAGGGGAAGG GGTGCCTGGCGGGTACTTTTCTATCTTTTATTTCCAGATTTTTTTTGTATCTAAACTTGAAGATTTGTATTATACAAGGACAGCCAATAA >23252_23252_3_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000402589_NUMBL_chr19_41192900_ENST00000252891_length(amino acids)=643AA_BP=42 MLGITSCSDQQAKEGEGLEGSSTGSSSGNHGGSGGGNGHKPGGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRRKPAY VPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSF CAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAER EAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLR LNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERW LEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVP VVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATVEKPSNP -------------------------------------------------------------- >23252_23252_4_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000414866_NUMBL_chr19_41192900_ENST00000252891_length(transcript)=2752nt_BP=169nt ATTGCGTAGTTCCGAATACCCTCGGCCACACCTGGCCTTCTCCATGCTCGGAATAACTTCCTGCAGCGACCAACAGGCTAAAGAGGGGGA AGGTCTGGAGGGATCCAGCACCGGCTCCTCCTCCGGCAACCACGGTGGGAGCGGCGGAGGAAATGGACATAAACCCGGGGGCGGACCCCG GAGGCCTGAGCGGCACCTGCCCCCAGCCCCCTGTGGGGCCCCGGGGCCCCCAGAAACCTGCAGGACGGAGCCAGACGGGGCGGGCACCAT GAACAAGTTACGGCAGAGCCTGCGGCGGAGGAAGCCAGCCTACGTGCCCGAGGCGTCGCGCCCGCACCAGTGGCAGGCAGACGAGGACGC GGTGCGGAAGGGCACGTGCAGCTTCCCGGTCAGGTACCTGGGTCACGTGGAGGTAGAGGAGTCCCGGGGAATGCACGTGTGTGAAGATGC GGTGAAGAAGCTGAAGGCGATGGGCCGAAAGTCCGTGAAGTCTGTCCTGTGGGTGTCAGCCGATGGGCTCCGAGTGGTGGACGACAAAAC CAAGGATCTTCTGGTCGACCAGACCATCGAAAAGGTCTCCTTTTGTGCTCCTGACCGCAACCTGGACAAGGCTTTCTCCTATATCTGTCG TGACGGGACTACCCGCCGCTGGATCTGCCACTGTTTTCTGGCACTGAAGGACTCCGGCGAGAGGCTGAGCCACGCTGTGGGCTGTGCTTT TGCCGCCTGCCTGGAGCGAAAACAGCGACGGGAGAAGGAATGTGGGGTCACGGCCGCCTTCGATGCCAGCCGCACCAGCTTCGCCCGCGA GGGCTCCTTCCGCCTGTCTGGGGGTGGGCGGCCTGCTGAGCGAGAGGCCCCGGACAAGAAGAAAGCAGAGGCAGCAGCTGCCCCCACTGT GGCTCCTGGCCCTGCCCAGCCTGGGCACGTGTCCCCGACACCAGCCACCACATCCCCTGGTGAGAAGGGTGAGGCAGGCACCCCTGTGGC TGCAGGCACCACTGCGGCCGCCATCCCCCGGCGCCATGCACCCCTGGAGCAGCTGGTTCGCCAGGGCTCCTTCCGTGGGTTCCCAGCACT CAGCCAGAAGAACTCGCCTTTCAAACGGCAGCTGAGCCTACGGCTGAATGAGCTGCCATCCACGCTGCAGCGCCGCACTGACTTCCAGGT GAAGGGCACAGTGCCTGAGATGGAGCCTCCTGGTGCCGGCGACAGTGACAGCATCAACGCTCTGTGCACACAGATCAGTTCATCTTTTGC CAGTGCTGGAGCGCCAGCACCAGGGCCACCACCTGCCACAACAGGGACTTCTGCCTGGGGTGAGCCCTCCGTGCCCCCTGCAGCTGCCTT CCAGCCTGGGCACAAGCGGACACCTTCAGAGGCTGAGCGATGGCTGGAGGAGGTGTCACAGGTGGCCAAGGCCCAGCAGCAGCAGCAGCA GCAACAGCAACAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAAGCAGCCTCAGTGGCCCCAGTGCCCACCATGCCTCCTGCCCTGCAGCC TTTCCCCGCCCCCGTGGGGCCCTTTGACGCTGCACCTGCCCAAGTGGCCGTGTTCCTGCCACCCCCACACATGCAGCCCCCTTTTGTGCC CGCCTACCCGGGCTTGGGCTACCCACCGATGCCCCGGGTGCCCGTGGTGGGCATCACACCCTCACAGATGGTGGCAAACGCCTTCTGCTC AGCCGCCCAGCTCCAGCCTCAGCCTGCCACTCTGCTTGGGAAAGCTGGGGCCTTCCCGCCCCCTGCCATACCCAGTGCCCCTGGGAGCCA GGCCCGCCCTCGCCCCAATGGGGCCCCCTGGCCCCCTGAGCCAGCGCCTGCCCCAGCTCCAGAGTTGGACCCCTTTGAGGCCCAGTGGGC GGCATTAGAAGGCAAAGCCACTGTAGAGAAACCCTCCAACCCCTTTTCTGGCGACCTGCAAAAGACATTCGAGATTGAACTGTAGCCCGA GCCGCCCCACCCACTCCATCATCTCCAGGTGCCCCACGCCTGGGGGTGGAGGCACAACCTCTCCCCTAACCCTGCTCCCTGGGGCTGCGC CCCTCAACACCCTCTCAACACCCCCCTCCCTCAACCACCCCGACAACCACTACAGAACCAACATTGTGACGCCCAGGTTGCAACAGGATG GAATTCAGGGACGGACCCAGCCTGGCTAAGGGAACCATTTCACTGCCGGACTTAGGCTGGCAATGCCCCCTTCCCCAACCCCAGACACAG GGGTTGGCCACAATCCCACTGAATGCCCTTGGTTCACACTCCATTTCCCAGTTTCTGTTGACCCCCACCTTCCAGTGTTGGACAGGATGG AGGGGGGACACTTGCTTAGGGGCTCTCCTGGGCCCCACACCAGTGCCCACCCCAAATCTGGTCGTCTCCTCCCCCCATGCACAGCACAAG CTAAGGGCTGCCCTCTGCCCACACGCTGCGTTCACTGCCAATGCTGTACTCACCTCCATCACCCTCCAACTTTGGGGCCCATGTCTTCCT TGGGCCAAGGTCTCATGGGGGCTAGGGCCAAGTTGGGGGCCCAGGAGGCGGGGAGGGAGGAGGAGGAGAAGATGCGCAGTTACCTCATGT CGGTGCCCGCTGGGGAGGGGTCCGGGAAGAAGGGGAAGGGGTGCCTGGCGGGTACTTTTCTATCTTTTATTTCCAGATTTTTTTTGTATC >23252_23252_4_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000414866_NUMBL_chr19_41192900_ENST00000252891_length(amino acids)=657AA_BP=56 LRSSEYPRPHLAFSMLGITSCSDQQAKEGEGLEGSSTGSSSGNHGGSGGGNGHKPGGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTM NKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDKT KDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFARE GSFRLSGGGRPAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPAL SQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAF QPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVP AYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWA -------------------------------------------------------------- >23252_23252_5_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000418261_NUMBL_chr19_41192900_ENST00000252891_length(transcript)=3576nt_BP=993nt GCAGAGATGAAGTTCCAGGGGCCCCTGGCCTGCCTCCTGCTGGCCCTCTGCCTGGGCAGTGGGGAGGCTGGCCCCCTGCAGAGCGGAGAG GAAAGCACTGGGACAAATATTGGGGAGGCCCTTGGACATGGCCTGGGAGACGCCCTGAGCGAAGGGGTGGGAAAGGCCATTGGCAAAGAG GCCGGAGGGGCAGCTGGCTCTAAAGTCAGTGAGGCCCTTGGCCAAGGGACCAGAGAAGCAGTTGGCACTGGAGTCAGGCAGGTTCCAGGC TTTGGCGTAGCAGATGCTTTGGGCAACAGGGTCGGGGAAGCAGCCCATGCTCTGGGAAACACTGGGCACGAGATTGGCAGACAGGCAGAA GATGTCATTCGACACGGAGCAGATGCTGTCCGCGGCTCCTGGCAGGGGGTGCCTGGCCACAATGGTGCTTGGGAAACTTCTGGAGGCCAT GGCATCTTTGGCTCTCAAGGTGGCCTTGGAGGCCAGGGCCAGGGCAATCCTGGAGGTCTGGGGACTCCGTGGGTCCACGGATACCCCGGA AACTCAGCAGGCAGCTTTGGAATGAATCCTCAGGGAGCTCCCTGGGGTCAAGGAGGCAATGGAGGGCCACCAAACTTTGGGACCAACACT CAGGGAGCTGTGGCCCAGCCTGGCTATGGTTCAGTGAGAGCCAGCAACCAGAATGAAGGGTGCACGAATCCCCCACCATCTGGCTCAGGT GGAGGCTCCAGCAACTCTGGGGGAGGCAGCGGCTCACAGTCGGGCAGCAGTGGCAGTGGCAGCAATGGTGACAACAACAATGGCAGCAGC AGTGGTGGCAGCAGCAGTGGCAGCAGCAGTGGCGGCAGCAGTGGCGGCAGCAGTGGTGGCAGCAGTGGCAACAGTGGTGGCAGCAGAGGT GACAGCGGCAGTGAGTCCTCCTGGGGATCCAGCACCGGCTCCTCCTCCGGCAACCACGGTGGGAGCGGCGGAGGAAATGGACATAAACCC GGGGGCGGACCCCGGAGGCCTGAGCGGCACCTGCCCCCAGCCCCCTGTGGGGCCCCGGGGCCCCCAGAAACCTGCAGGACGGAGCCAGAC GGGGCGGGCACCATGAACAAGTTACGGCAGAGCCTGCGGCGGAGGAAGCCAGCCTACGTGCCCGAGGCGTCGCGCCCGCACCAGTGGCAG GCAGACGAGGACGCGGTGCGGAAGGGCACGTGCAGCTTCCCGGTCAGGTACCTGGGTCACGTGGAGGTAGAGGAGTCCCGGGGAATGCAC GTGTGTGAAGATGCGGTGAAGAAGCTGAAGGCGATGGGCCGAAAGTCCGTGAAGTCTGTCCTGTGGGTGTCAGCCGATGGGCTCCGAGTG GTGGACGACAAAACCAAGGATCTTCTGGTCGACCAGACCATCGAAAAGGTCTCCTTTTGTGCTCCTGACCGCAACCTGGACAAGGCTTTC TCCTATATCTGTCGTGACGGGACTACCCGCCGCTGGATCTGCCACTGTTTTCTGGCACTGAAGGACTCCGGCGAGAGGCTGAGCCACGCT GTGGGCTGTGCTTTTGCCGCCTGCCTGGAGCGAAAACAGCGACGGGAGAAGGAATGTGGGGTCACGGCCGCCTTCGATGCCAGCCGCACC AGCTTCGCCCGCGAGGGCTCCTTCCGCCTGTCTGGGGGTGGGCGGCCTGCTGAGCGAGAGGCCCCGGACAAGAAGAAAGCAGAGGCAGCA GCTGCCCCCACTGTGGCTCCTGGCCCTGCCCAGCCTGGGCACGTGTCCCCGACACCAGCCACCACATCCCCTGGTGAGAAGGGTGAGGCA GGCACCCCTGTGGCTGCAGGCACCACTGCGGCCGCCATCCCCCGGCGCCATGCACCCCTGGAGCAGCTGGTTCGCCAGGGCTCCTTCCGT GGGTTCCCAGCACTCAGCCAGAAGAACTCGCCTTTCAAACGGCAGCTGAGCCTACGGCTGAATGAGCTGCCATCCACGCTGCAGCGCCGC ACTGACTTCCAGGTGAAGGGCACAGTGCCTGAGATGGAGCCTCCTGGTGCCGGCGACAGTGACAGCATCAACGCTCTGTGCACACAGATC AGTTCATCTTTTGCCAGTGCTGGAGCGCCAGCACCAGGGCCACCACCTGCCACAACAGGGACTTCTGCCTGGGGTGAGCCCTCCGTGCCC CCTGCAGCTGCCTTCCAGCCTGGGCACAAGCGGACACCTTCAGAGGCTGAGCGATGGCTGGAGGAGGTGTCACAGGTGGCCAAGGCCCAG CAGCAGCAGCAGCAGCAACAGCAACAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAAGCAGCCTCAGTGGCCCCAGTGCCCACCATGCCT CCTGCCCTGCAGCCTTTCCCCGCCCCCGTGGGGCCCTTTGACGCTGCACCTGCCCAAGTGGCCGTGTTCCTGCCACCCCCACACATGCAG CCCCCTTTTGTGCCCGCCTACCCGGGCTTGGGCTACCCACCGATGCCCCGGGTGCCCGTGGTGGGCATCACACCCTCACAGATGGTGGCA AACGCCTTCTGCTCAGCCGCCCAGCTCCAGCCTCAGCCTGCCACTCTGCTTGGGAAAGCTGGGGCCTTCCCGCCCCCTGCCATACCCAGT GCCCCTGGGAGCCAGGCCCGCCCTCGCCCCAATGGGGCCCCCTGGCCCCCTGAGCCAGCGCCTGCCCCAGCTCCAGAGTTGGACCCCTTT GAGGCCCAGTGGGCGGCATTAGAAGGCAAAGCCACTGTAGAGAAACCCTCCAACCCCTTTTCTGGCGACCTGCAAAAGACATTCGAGATT GAACTGTAGCCCGAGCCGCCCCACCCACTCCATCATCTCCAGGTGCCCCACGCCTGGGGGTGGAGGCACAACCTCTCCCCTAACCCTGCT CCCTGGGGCTGCGCCCCTCAACACCCTCTCAACACCCCCCTCCCTCAACCACCCCGACAACCACTACAGAACCAACATTGTGACGCCCAG GTTGCAACAGGATGGAATTCAGGGACGGACCCAGCCTGGCTAAGGGAACCATTTCACTGCCGGACTTAGGCTGGCAATGCCCCCTTCCCC AACCCCAGACACAGGGGTTGGCCACAATCCCACTGAATGCCCTTGGTTCACACTCCATTTCCCAGTTTCTGTTGACCCCCACCTTCCAGT GTTGGACAGGATGGAGGGGGGACACTTGCTTAGGGGCTCTCCTGGGCCCCACACCAGTGCCCACCCCAAATCTGGTCGTCTCCTCCCCCC ATGCACAGCACAAGCTAAGGGCTGCCCTCTGCCCACACGCTGCGTTCACTGCCAATGCTGTACTCACCTCCATCACCCTCCAACTTTGGG GCCCATGTCTTCCTTGGGCCAAGGTCTCATGGGGGCTAGGGCCAAGTTGGGGGCCCAGGAGGCGGGGAGGGAGGAGGAGGAGAAGATGCG CAGTTACCTCATGTCGGTGCCCGCTGGGGAGGGGTCCGGGAAGAAGGGGAAGGGGTGCCTGGCGGGTACTTTTCTATCTTTTATTTCCAG >23252_23252_5_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000418261_NUMBL_chr19_41192900_ENST00000252891_length(amino acids)=930AA_BP=329 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFG VADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG GSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGGGPRRPERHLPPAPCGAPGPPETCRTEPDGA GTMNKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVD DKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSF AREGSFRLSGGGRPAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGF PALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPA AAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPP FVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEA -------------------------------------------------------------- >23252_23252_6_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000419602_NUMBL_chr19_41192900_ENST00000252891_length(transcript)=3394nt_BP=811nt GGCAGAGATGAAGTTCCAGGGGCCCCTGGCCTGCCTCCTGCTGGCCCTCTGCCTGGGCAGTGGGGAGGCTGGCCCCCTGCAGAGCGGAGA GGAAAGCACTGGGACAAATATTGGGGAGGCCCTTGGACATGGCCTGGGAGACGCCCTGAGCGAAGGGGTGGGAAAGGCCATTGGCAAAGA GGCCGGAGGGGCAGCTGGCTCTAAAGTCAGTGAGGCCCTTGGCCAAGGGACCAGAGAAGCAGTTGGCACTGGAGTCAGGCAGGTTCCAGG CTTTGGCGTAGCAGATGCTTTGGGCAACAGGGTCGGGGAAGCAGCCCATGCTCTGGGAAACACTGGGCACGAGATTGGCAGACAGGCAGA AGATGTCATTCGACACGGAGCAGATGCTGTCCGCGGCTCCTGGCAGGGGGTGCCTGGCCACAATGGTGCTTGGGAAACTTCTGGAGGCCA TGGCATCTTTGGCTCTCAAGGTGGCCTTGGAGGCCAGGGCCAGGGCAATCCTGGAGGTCTGGGGACTCCGTGGGTCCACGGATACCCCGG AAACTCAGCAGGCAGCTTTGGAATGAATCCTCAGGGAGCTCCCTGGGGTCAAGGAGGCAATGGAGGGCCACCAAACTTTGGGACCAACAC TCAGGGAGCTGTGGCCCAGCCTGGCTATGGTTCAGTGAGAGCCAGCAACCAGAATGAAGGGTGCACGAATCCCCCACCATCTGGCTCAGG TGGAGGCTCCAGCAACTCTGGGGGATCCAGCACCGGCTCCTCCTCCGGCAACCACGGTGGGAGCGGCGGAGGAAATGGACATAAACCCGG GGGCGGACCCCGGAGGCCTGAGCGGCACCTGCCCCCAGCCCCCTGTGGGGCCCCGGGGCCCCCAGAAACCTGCAGGACGGAGCCAGACGG GGCGGGCACCATGAACAAGTTACGGCAGAGCCTGCGGCGGAGGAAGCCAGCCTACGTGCCCGAGGCGTCGCGCCCGCACCAGTGGCAGGC AGACGAGGACGCGGTGCGGAAGGGCACGTGCAGCTTCCCGGTCAGGTACCTGGGTCACGTGGAGGTAGAGGAGTCCCGGGGAATGCACGT GTGTGAAGATGCGGTGAAGAAGCTGAAGGCGATGGGCCGAAAGTCCGTGAAGTCTGTCCTGTGGGTGTCAGCCGATGGGCTCCGAGTGGT GGACGACAAAACCAAGGATCTTCTGGTCGACCAGACCATCGAAAAGGTCTCCTTTTGTGCTCCTGACCGCAACCTGGACAAGGCTTTCTC CTATATCTGTCGTGACGGGACTACCCGCCGCTGGATCTGCCACTGTTTTCTGGCACTGAAGGACTCCGGCGAGAGGCTGAGCCACGCTGT GGGCTGTGCTTTTGCCGCCTGCCTGGAGCGAAAACAGCGACGGGAGAAGGAATGTGGGGTCACGGCCGCCTTCGATGCCAGCCGCACCAG CTTCGCCCGCGAGGGCTCCTTCCGCCTGTCTGGGGGTGGGCGGCCTGCTGAGCGAGAGGCCCCGGACAAGAAGAAAGCAGAGGCAGCAGC TGCCCCCACTGTGGCTCCTGGCCCTGCCCAGCCTGGGCACGTGTCCCCGACACCAGCCACCACATCCCCTGGTGAGAAGGGTGAGGCAGG CACCCCTGTGGCTGCAGGCACCACTGCGGCCGCCATCCCCCGGCGCCATGCACCCCTGGAGCAGCTGGTTCGCCAGGGCTCCTTCCGTGG GTTCCCAGCACTCAGCCAGAAGAACTCGCCTTTCAAACGGCAGCTGAGCCTACGGCTGAATGAGCTGCCATCCACGCTGCAGCGCCGCAC TGACTTCCAGGTGAAGGGCACAGTGCCTGAGATGGAGCCTCCTGGTGCCGGCGACAGTGACAGCATCAACGCTCTGTGCACACAGATCAG TTCATCTTTTGCCAGTGCTGGAGCGCCAGCACCAGGGCCACCACCTGCCACAACAGGGACTTCTGCCTGGGGTGAGCCCTCCGTGCCCCC TGCAGCTGCCTTCCAGCCTGGGCACAAGCGGACACCTTCAGAGGCTGAGCGATGGCTGGAGGAGGTGTCACAGGTGGCCAAGGCCCAGCA GCAGCAGCAGCAGCAACAGCAACAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAAGCAGCCTCAGTGGCCCCAGTGCCCACCATGCCTCC TGCCCTGCAGCCTTTCCCCGCCCCCGTGGGGCCCTTTGACGCTGCACCTGCCCAAGTGGCCGTGTTCCTGCCACCCCCACACATGCAGCC CCCTTTTGTGCCCGCCTACCCGGGCTTGGGCTACCCACCGATGCCCCGGGTGCCCGTGGTGGGCATCACACCCTCACAGATGGTGGCAAA CGCCTTCTGCTCAGCCGCCCAGCTCCAGCCTCAGCCTGCCACTCTGCTTGGGAAAGCTGGGGCCTTCCCGCCCCCTGCCATACCCAGTGC CCCTGGGAGCCAGGCCCGCCCTCGCCCCAATGGGGCCCCCTGGCCCCCTGAGCCAGCGCCTGCCCCAGCTCCAGAGTTGGACCCCTTTGA GGCCCAGTGGGCGGCATTAGAAGGCAAAGCCACTGTAGAGAAACCCTCCAACCCCTTTTCTGGCGACCTGCAAAAGACATTCGAGATTGA ACTGTAGCCCGAGCCGCCCCACCCACTCCATCATCTCCAGGTGCCCCACGCCTGGGGGTGGAGGCACAACCTCTCCCCTAACCCTGCTCC CTGGGGCTGCGCCCCTCAACACCCTCTCAACACCCCCCTCCCTCAACCACCCCGACAACCACTACAGAACCAACATTGTGACGCCCAGGT TGCAACAGGATGGAATTCAGGGACGGACCCAGCCTGGCTAAGGGAACCATTTCACTGCCGGACTTAGGCTGGCAATGCCCCCTTCCCCAA CCCCAGACACAGGGGTTGGCCACAATCCCACTGAATGCCCTTGGTTCACACTCCATTTCCCAGTTTCTGTTGACCCCCACCTTCCAGTGT TGGACAGGATGGAGGGGGGACACTTGCTTAGGGGCTCTCCTGGGCCCCACACCAGTGCCCACCCCAAATCTGGTCGTCTCCTCCCCCCAT GCACAGCACAAGCTAAGGGCTGCCCTCTGCCCACACGCTGCGTTCACTGCCAATGCTGTACTCACCTCCATCACCCTCCAACTTTGGGGC CCATGTCTTCCTTGGGCCAAGGTCTCATGGGGGCTAGGGCCAAGTTGGGGGCCCAGGAGGCGGGGAGGGAGGAGGAGGAGAAGATGCGCA GTTACCTCATGTCGGTGCCCGCTGGGGAGGGGTCCGGGAAGAAGGGGAAGGGGTGCCTGGCGGGTACTTTTCTATCTTTTATTTCCAGAT >23252_23252_6_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000419602_NUMBL_chr19_41192900_ENST00000252891_length(amino acids)=869AA_BP=268 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFG VADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGSSTGSSSGNHGGSGGGNGHKPGGG PRRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCE DAVKKLKAMGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGC AFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTP VAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSS FASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPAL QPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPG -------------------------------------------------------------- >23252_23252_7_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000424570_NUMBL_chr19_41192900_ENST00000252891_length(transcript)=3576nt_BP=993nt GCAGAGATGAAGTTCCAGGGGCCCCTGGCCTGCCTCCTGCTGGCCCTCTGCCTGGGCAGTGGGGAGGCTGGCCCCCTGCAGAGCGGAGAG GAAAGCACTGGGACAAATATTGGGGAGGCCCTTGGACATGGCCTGGGAGACGCCCTGAGCGAAGGGGTGGGAAAGGCCATTGGCAAAGAG GCCGGAGGGGCAGCTGGCTCTAAAGTCAGTGAGGCCCTTGGCCAAGGGACCAGAGAAGCAGTTGGCACTGGAGTCAGGCAGGTTCCAGGC TTTGGCGTAGCAGATGCTTTGGGCAACAGGGTCGGGGAAGCAGCCCATGCTCTGGGAAACACTGGGCACGAGATTGGCAGACAGGCAGAA GATGTCATTCGACACGGAGCAGATGCTGTCCGCGGCTCCTGGCAGGGGGTGCCTGGCCACAATGGTGCTTGGGAAACTTCTGGAGGCCAT GGCATCTTTGGCTCTCAAGGTGGCCTTGGAGGCCAGGGCCAGGGCAATCCTGGAGGTCTGGGGACTCCGTGGGTCCACGGATACCCCGGA AACTCAGCAGGCAGCTTTGGAATGAATCCTCAGGGAGCTCCCTGGGGTCAAGGAGGCAATGGAGGGCCACCAAACTTTGGGACCAACACT CAGGGAGCTGTGGCCCAGCCTGGCTATGGTTCAGTGAGAGCCAGCAACCAGAATGAAGGGTGCACGAATCCCCCACCATCTGGCTCAGGT GGAGGCTCCAGCAACTCTGGGGGAGGCAGCGGCTCACAGTCGGGCAGCAGTGGCAGTGGCAGCAATGGTGACAACAACAATGGCAGCAGC AGTGGTGGCAGCAGCAGTGGCAGCAGCAGTGGCGGCAGCAGTGGCGGCAGCAGTGGTGGCAGCAGTGGCAACAGTGGTGGCAGCAGAGGT GACAGCGGCAGTGAGTCCTCCTGGGGATCCAGCACCGGCTCCTCCTCCGGCAACCACGGTGGGAGCGGCGGAGGAAATGGACATAAACCC GGGGGCGGACCCCGGAGGCCTGAGCGGCACCTGCCCCCAGCCCCCTGTGGGGCCCCGGGGCCCCCAGAAACCTGCAGGACGGAGCCAGAC GGGGCGGGCACCATGAACAAGTTACGGCAGAGCCTGCGGCGGAGGAAGCCAGCCTACGTGCCCGAGGCGTCGCGCCCGCACCAGTGGCAG GCAGACGAGGACGCGGTGCGGAAGGGCACGTGCAGCTTCCCGGTCAGGTACCTGGGTCACGTGGAGGTAGAGGAGTCCCGGGGAATGCAC GTGTGTGAAGATGCGGTGAAGAAGCTGAAGGCGATGGGCCGAAAGTCCGTGAAGTCTGTCCTGTGGGTGTCAGCCGATGGGCTCCGAGTG GTGGACGACAAAACCAAGGATCTTCTGGTCGACCAGACCATCGAAAAGGTCTCCTTTTGTGCTCCTGACCGCAACCTGGACAAGGCTTTC TCCTATATCTGTCGTGACGGGACTACCCGCCGCTGGATCTGCCACTGTTTTCTGGCACTGAAGGACTCCGGCGAGAGGCTGAGCCACGCT GTGGGCTGTGCTTTTGCCGCCTGCCTGGAGCGAAAACAGCGACGGGAGAAGGAATGTGGGGTCACGGCCGCCTTCGATGCCAGCCGCACC AGCTTCGCCCGCGAGGGCTCCTTCCGCCTGTCTGGGGGTGGGCGGCCTGCTGAGCGAGAGGCCCCGGACAAGAAGAAAGCAGAGGCAGCA GCTGCCCCCACTGTGGCTCCTGGCCCTGCCCAGCCTGGGCACGTGTCCCCGACACCAGCCACCACATCCCCTGGTGAGAAGGGTGAGGCA GGCACCCCTGTGGCTGCAGGCACCACTGCGGCCGCCATCCCCCGGCGCCATGCACCCCTGGAGCAGCTGGTTCGCCAGGGCTCCTTCCGT GGGTTCCCAGCACTCAGCCAGAAGAACTCGCCTTTCAAACGGCAGCTGAGCCTACGGCTGAATGAGCTGCCATCCACGCTGCAGCGCCGC ACTGACTTCCAGGTGAAGGGCACAGTGCCTGAGATGGAGCCTCCTGGTGCCGGCGACAGTGACAGCATCAACGCTCTGTGCACACAGATC AGTTCATCTTTTGCCAGTGCTGGAGCGCCAGCACCAGGGCCACCACCTGCCACAACAGGGACTTCTGCCTGGGGTGAGCCCTCCGTGCCC CCTGCAGCTGCCTTCCAGCCTGGGCACAAGCGGACACCTTCAGAGGCTGAGCGATGGCTGGAGGAGGTGTCACAGGTGGCCAAGGCCCAG CAGCAGCAGCAGCAGCAACAGCAACAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAAGCAGCCTCAGTGGCCCCAGTGCCCACCATGCCT CCTGCCCTGCAGCCTTTCCCCGCCCCCGTGGGGCCCTTTGACGCTGCACCTGCCCAAGTGGCCGTGTTCCTGCCACCCCCACACATGCAG CCCCCTTTTGTGCCCGCCTACCCGGGCTTGGGCTACCCACCGATGCCCCGGGTGCCCGTGGTGGGCATCACACCCTCACAGATGGTGGCA AACGCCTTCTGCTCAGCCGCCCAGCTCCAGCCTCAGCCTGCCACTCTGCTTGGGAAAGCTGGGGCCTTCCCGCCCCCTGCCATACCCAGT GCCCCTGGGAGCCAGGCCCGCCCTCGCCCCAATGGGGCCCCCTGGCCCCCTGAGCCAGCGCCTGCCCCAGCTCCAGAGTTGGACCCCTTT GAGGCCCAGTGGGCGGCATTAGAAGGCAAAGCCACTGTAGAGAAACCCTCCAACCCCTTTTCTGGCGACCTGCAAAAGACATTCGAGATT GAACTGTAGCCCGAGCCGCCCCACCCACTCCATCATCTCCAGGTGCCCCACGCCTGGGGGTGGAGGCACAACCTCTCCCCTAACCCTGCT CCCTGGGGCTGCGCCCCTCAACACCCTCTCAACACCCCCCTCCCTCAACCACCCCGACAACCACTACAGAACCAACATTGTGACGCCCAG GTTGCAACAGGATGGAATTCAGGGACGGACCCAGCCTGGCTAAGGGAACCATTTCACTGCCGGACTTAGGCTGGCAATGCCCCCTTCCCC AACCCCAGACACAGGGGTTGGCCACAATCCCACTGAATGCCCTTGGTTCACACTCCATTTCCCAGTTTCTGTTGACCCCCACCTTCCAGT GTTGGACAGGATGGAGGGGGGACACTTGCTTAGGGGCTCTCCTGGGCCCCACACCAGTGCCCACCCCAAATCTGGTCGTCTCCTCCCCCC ATGCACAGCACAAGCTAAGGGCTGCCCTCTGCCCACACGCTGCGTTCACTGCCAATGCTGTACTCACCTCCATCACCCTCCAACTTTGGG GCCCATGTCTTCCTTGGGCCAAGGTCTCATGGGGGCTAGGGCCAAGTTGGGGGCCCAGGAGGCGGGGAGGGAGGAGGAGGAGAAGATGCG CAGTTACCTCATGTCGGTGCCCGCTGGGGAGGGGTCCGGGAAGAAGGGGAAGGGGTGCCTGGCGGGTACTTTTCTATCTTTTATTTCCAG >23252_23252_7_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000424570_NUMBL_chr19_41192900_ENST00000252891_length(amino acids)=930AA_BP=329 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFG VADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG GSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGGGPRRPERHLPPAPCGAPGPPETCRTEPDGA GTMNKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVD DKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSF AREGSFRLSGGGRPAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGF PALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPA AAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPP FVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEA -------------------------------------------------------------- >23252_23252_8_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000429837_NUMBL_chr19_41192900_ENST00000252891_length(transcript)=3393nt_BP=810nt GCAGAGATGAAGTTCCAGGGGCCCCTGGCCTGCCTCCTGCTGGCCCTCTGCCTGGGCAGTGGGGAGGCTGGCCCCCTGCAGAGCGGAGAG GAAAGCACTGGGACAAATATTGGGGAGGCCCTTGGACATGGCCTGGGAGACGCCCTGAGCGAAGGGGTGGGAAAGGCCATTGGCAAAGAG GCCGGAGGGGCAGCTGGCTCTAAAGTCAGTGAGGCCCTTGGCCAAGGGACCAGAGAAGCAGTTGGCACTGGAGTCAGGCAGGTTCCAGGC TTTGGCGTAGCAGATGCTTTGGGCAACAGGGTCGGGGAAGCAGCCCATGCTCTGGGAAACACTGGGCACGAGATTGGCAGACAGGCAGAA GATGTCATTCGACACGGAGCAGATGCTGTCCGCGGCTCCTGGCAGGGGGTGCCTGGCCACAATGGTGCTTGGGAAACTTCTGGAGGCCAT GGCATCTTTGGCTCTCAAGGTGGCCTTGGAGGCCAGGGCCAGGGCAATCCTGGAGGTCTGGGGACTCCGTGGGTCCACGGATACCCCGGA AACTCAGCAGGCAGCTTTGGAATGAATCCTCAGGGAGCTCCCTGGGGTCAAGGAGGCAATGGAGGGCCACCAAACTTTGGGACCAACACT CAGGGAGCTGTGGCCCAGCCTGGCTATGGTTCAGTGAGAGCCAGCAACCAGAATGAAGGGTGCACGAATCCCCCACCATCTGGCTCAGGT GGAGGCTCCAGCAACTCTGGGGGATCCAGCACCGGCTCCTCCTCCGGCAACCACGGTGGGAGCGGCGGAGGAAATGGACATAAACCCGGG GGCGGACCCCGGAGGCCTGAGCGGCACCTGCCCCCAGCCCCCTGTGGGGCCCCGGGGCCCCCAGAAACCTGCAGGACGGAGCCAGACGGG GCGGGCACCATGAACAAGTTACGGCAGAGCCTGCGGCGGAGGAAGCCAGCCTACGTGCCCGAGGCGTCGCGCCCGCACCAGTGGCAGGCA GACGAGGACGCGGTGCGGAAGGGCACGTGCAGCTTCCCGGTCAGGTACCTGGGTCACGTGGAGGTAGAGGAGTCCCGGGGAATGCACGTG TGTGAAGATGCGGTGAAGAAGCTGAAGGCGATGGGCCGAAAGTCCGTGAAGTCTGTCCTGTGGGTGTCAGCCGATGGGCTCCGAGTGGTG GACGACAAAACCAAGGATCTTCTGGTCGACCAGACCATCGAAAAGGTCTCCTTTTGTGCTCCTGACCGCAACCTGGACAAGGCTTTCTCC TATATCTGTCGTGACGGGACTACCCGCCGCTGGATCTGCCACTGTTTTCTGGCACTGAAGGACTCCGGCGAGAGGCTGAGCCACGCTGTG GGCTGTGCTTTTGCCGCCTGCCTGGAGCGAAAACAGCGACGGGAGAAGGAATGTGGGGTCACGGCCGCCTTCGATGCCAGCCGCACCAGC TTCGCCCGCGAGGGCTCCTTCCGCCTGTCTGGGGGTGGGCGGCCTGCTGAGCGAGAGGCCCCGGACAAGAAGAAAGCAGAGGCAGCAGCT GCCCCCACTGTGGCTCCTGGCCCTGCCCAGCCTGGGCACGTGTCCCCGACACCAGCCACCACATCCCCTGGTGAGAAGGGTGAGGCAGGC ACCCCTGTGGCTGCAGGCACCACTGCGGCCGCCATCCCCCGGCGCCATGCACCCCTGGAGCAGCTGGTTCGCCAGGGCTCCTTCCGTGGG TTCCCAGCACTCAGCCAGAAGAACTCGCCTTTCAAACGGCAGCTGAGCCTACGGCTGAATGAGCTGCCATCCACGCTGCAGCGCCGCACT GACTTCCAGGTGAAGGGCACAGTGCCTGAGATGGAGCCTCCTGGTGCCGGCGACAGTGACAGCATCAACGCTCTGTGCACACAGATCAGT TCATCTTTTGCCAGTGCTGGAGCGCCAGCACCAGGGCCACCACCTGCCACAACAGGGACTTCTGCCTGGGGTGAGCCCTCCGTGCCCCCT GCAGCTGCCTTCCAGCCTGGGCACAAGCGGACACCTTCAGAGGCTGAGCGATGGCTGGAGGAGGTGTCACAGGTGGCCAAGGCCCAGCAG CAGCAGCAGCAGCAACAGCAACAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAAGCAGCCTCAGTGGCCCCAGTGCCCACCATGCCTCCT GCCCTGCAGCCTTTCCCCGCCCCCGTGGGGCCCTTTGACGCTGCACCTGCCCAAGTGGCCGTGTTCCTGCCACCCCCACACATGCAGCCC CCTTTTGTGCCCGCCTACCCGGGCTTGGGCTACCCACCGATGCCCCGGGTGCCCGTGGTGGGCATCACACCCTCACAGATGGTGGCAAAC GCCTTCTGCTCAGCCGCCCAGCTCCAGCCTCAGCCTGCCACTCTGCTTGGGAAAGCTGGGGCCTTCCCGCCCCCTGCCATACCCAGTGCC CCTGGGAGCCAGGCCCGCCCTCGCCCCAATGGGGCCCCCTGGCCCCCTGAGCCAGCGCCTGCCCCAGCTCCAGAGTTGGACCCCTTTGAG GCCCAGTGGGCGGCATTAGAAGGCAAAGCCACTGTAGAGAAACCCTCCAACCCCTTTTCTGGCGACCTGCAAAAGACATTCGAGATTGAA CTGTAGCCCGAGCCGCCCCACCCACTCCATCATCTCCAGGTGCCCCACGCCTGGGGGTGGAGGCACAACCTCTCCCCTAACCCTGCTCCC TGGGGCTGCGCCCCTCAACACCCTCTCAACACCCCCCTCCCTCAACCACCCCGACAACCACTACAGAACCAACATTGTGACGCCCAGGTT GCAACAGGATGGAATTCAGGGACGGACCCAGCCTGGCTAAGGGAACCATTTCACTGCCGGACTTAGGCTGGCAATGCCCCCTTCCCCAAC CCCAGACACAGGGGTTGGCCACAATCCCACTGAATGCCCTTGGTTCACACTCCATTTCCCAGTTTCTGTTGACCCCCACCTTCCAGTGTT GGACAGGATGGAGGGGGGACACTTGCTTAGGGGCTCTCCTGGGCCCCACACCAGTGCCCACCCCAAATCTGGTCGTCTCCTCCCCCCATG CACAGCACAAGCTAAGGGCTGCCCTCTGCCCACACGCTGCGTTCACTGCCAATGCTGTACTCACCTCCATCACCCTCCAACTTTGGGGCC CATGTCTTCCTTGGGCCAAGGTCTCATGGGGGCTAGGGCCAAGTTGGGGGCCCAGGAGGCGGGGAGGGAGGAGGAGGAGAAGATGCGCAG TTACCTCATGTCGGTGCCCGCTGGGGAGGGGTCCGGGAAGAAGGGGAAGGGGTGCCTGGCGGGTACTTTTCTATCTTTTATTTCCAGATT >23252_23252_8_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000429837_NUMBL_chr19_41192900_ENST00000252891_length(amino acids)=869AA_BP=268 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFG VADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGSSTGSSSGNHGGSGGGNGHKPGGG PRRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCE DAVKKLKAMGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGC AFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTP VAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSS FASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPAL QPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPG -------------------------------------------------------------- >23252_23252_9_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000436012_NUMBL_chr19_41192900_ENST00000252891_length(transcript)=2721nt_BP=138nt CTGGCCTTCTCCATGCTCGGAATAACTTCCTGCAGCGACCAACAGGCTAAAGAGGGGGAAGGTCTGGAGGGATCCAGCACCGGCTCCTCC TCCGGCAACCACGGTGGGAGCGGCGGAGGAAATGGACATAAACCCGGGGGCGGACCCCGGAGGCCTGAGCGGCACCTGCCCCCAGCCCCC TGTGGGGCCCCGGGGCCCCCAGAAACCTGCAGGACGGAGCCAGACGGGGCGGGCACCATGAACAAGTTACGGCAGAGCCTGCGGCGGAGG AAGCCAGCCTACGTGCCCGAGGCGTCGCGCCCGCACCAGTGGCAGGCAGACGAGGACGCGGTGCGGAAGGGCACGTGCAGCTTCCCGGTC AGGTACCTGGGTCACGTGGAGGTAGAGGAGTCCCGGGGAATGCACGTGTGTGAAGATGCGGTGAAGAAGCTGAAGGCGATGGGCCGAAAG TCCGTGAAGTCTGTCCTGTGGGTGTCAGCCGATGGGCTCCGAGTGGTGGACGACAAAACCAAGGATCTTCTGGTCGACCAGACCATCGAA AAGGTCTCCTTTTGTGCTCCTGACCGCAACCTGGACAAGGCTTTCTCCTATATCTGTCGTGACGGGACTACCCGCCGCTGGATCTGCCAC TGTTTTCTGGCACTGAAGGACTCCGGCGAGAGGCTGAGCCACGCTGTGGGCTGTGCTTTTGCCGCCTGCCTGGAGCGAAAACAGCGACGG GAGAAGGAATGTGGGGTCACGGCCGCCTTCGATGCCAGCCGCACCAGCTTCGCCCGCGAGGGCTCCTTCCGCCTGTCTGGGGGTGGGCGG CCTGCTGAGCGAGAGGCCCCGGACAAGAAGAAAGCAGAGGCAGCAGCTGCCCCCACTGTGGCTCCTGGCCCTGCCCAGCCTGGGCACGTG TCCCCGACACCAGCCACCACATCCCCTGGTGAGAAGGGTGAGGCAGGCACCCCTGTGGCTGCAGGCACCACTGCGGCCGCCATCCCCCGG CGCCATGCACCCCTGGAGCAGCTGGTTCGCCAGGGCTCCTTCCGTGGGTTCCCAGCACTCAGCCAGAAGAACTCGCCTTTCAAACGGCAG CTGAGCCTACGGCTGAATGAGCTGCCATCCACGCTGCAGCGCCGCACTGACTTCCAGGTGAAGGGCACAGTGCCTGAGATGGAGCCTCCT GGTGCCGGCGACAGTGACAGCATCAACGCTCTGTGCACACAGATCAGTTCATCTTTTGCCAGTGCTGGAGCGCCAGCACCAGGGCCACCA CCTGCCACAACAGGGACTTCTGCCTGGGGTGAGCCCTCCGTGCCCCCTGCAGCTGCCTTCCAGCCTGGGCACAAGCGGACACCTTCAGAG GCTGAGCGATGGCTGGAGGAGGTGTCACAGGTGGCCAAGGCCCAGCAGCAGCAGCAGCAGCAACAGCAACAGCAGCAGCAGCAGCAGCAG CAACAGCAGCAAGCAGCCTCAGTGGCCCCAGTGCCCACCATGCCTCCTGCCCTGCAGCCTTTCCCCGCCCCCGTGGGGCCCTTTGACGCT GCACCTGCCCAAGTGGCCGTGTTCCTGCCACCCCCACACATGCAGCCCCCTTTTGTGCCCGCCTACCCGGGCTTGGGCTACCCACCGATG CCCCGGGTGCCCGTGGTGGGCATCACACCCTCACAGATGGTGGCAAACGCCTTCTGCTCAGCCGCCCAGCTCCAGCCTCAGCCTGCCACT CTGCTTGGGAAAGCTGGGGCCTTCCCGCCCCCTGCCATACCCAGTGCCCCTGGGAGCCAGGCCCGCCCTCGCCCCAATGGGGCCCCCTGG CCCCCTGAGCCAGCGCCTGCCCCAGCTCCAGAGTTGGACCCCTTTGAGGCCCAGTGGGCGGCATTAGAAGGCAAAGCCACTGTAGAGAAA CCCTCCAACCCCTTTTCTGGCGACCTGCAAAAGACATTCGAGATTGAACTGTAGCCCGAGCCGCCCCACCCACTCCATCATCTCCAGGTG CCCCACGCCTGGGGGTGGAGGCACAACCTCTCCCCTAACCCTGCTCCCTGGGGCTGCGCCCCTCAACACCCTCTCAACACCCCCCTCCCT CAACCACCCCGACAACCACTACAGAACCAACATTGTGACGCCCAGGTTGCAACAGGATGGAATTCAGGGACGGACCCAGCCTGGCTAAGG GAACCATTTCACTGCCGGACTTAGGCTGGCAATGCCCCCTTCCCCAACCCCAGACACAGGGGTTGGCCACAATCCCACTGAATGCCCTTG GTTCACACTCCATTTCCCAGTTTCTGTTGACCCCCACCTTCCAGTGTTGGACAGGATGGAGGGGGGACACTTGCTTAGGGGCTCTCCTGG GCCCCACACCAGTGCCCACCCCAAATCTGGTCGTCTCCTCCCCCCATGCACAGCACAAGCTAAGGGCTGCCCTCTGCCCACACGCTGCGT TCACTGCCAATGCTGTACTCACCTCCATCACCCTCCAACTTTGGGGCCCATGTCTTCCTTGGGCCAAGGTCTCATGGGGGCTAGGGCCAA GTTGGGGGCCCAGGAGGCGGGGAGGGAGGAGGAGGAGAAGATGCGCAGTTACCTCATGTCGGTGCCCGCTGGGGAGGGGTCCGGGAAGAA GGGGAAGGGGTGCCTGGCGGGTACTTTTCTATCTTTTATTTCCAGATTTTTTTTGTATCTAAACTTGAAGATTTGTATTATACAAGGACA >23252_23252_9_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000436012_NUMBL_chr19_41192900_ENST00000252891_length(amino acids)=647AA_BP=46 LAFSMLGITSCSDQQAKEGEGLEGSSTGSSSGNHGGSGGGNGHKPGGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRR KPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIE KVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGR PAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQ LSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSE AERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPM PRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATVEK -------------------------------------------------------------- >23252_23252_10_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000440396_NUMBL_chr19_41192900_ENST00000252891_length(transcript)=3753nt_BP=1170nt GTGGACTCTGAGAAGCCCAGGCAGTTGAGGACAGGAGAGAGAAGGCTGCAGACCCAGAGGGAGGGAGGACAGGGAGTCGGAAGGAGGAGG ACAGAGGAGGGCACAGAGACGCAGAGCAAGGGCGGCAAGGAGGAGACCCTGGTGGGAGGAAGACACTCTGGAGAGAGAGGGGGCTGGGCA GAGATGAAGTTCCAGGGGCCCCTGGCCTGCCTCCTGCTGGCCCTCTGCCTGGGCAGTGGGGAGGCTGGCCCCCTGCAGAGCGGAGAGGAA AGCACTGGGACAAATATTGGGGAGGCCCTTGGACATGGCCTGGGAGACGCCCTGAGCGAAGGGGTGGGAAAGGCCATTGGCAAAGAGGCC GGAGGGGCAGCTGGCTCTAAAGTCAGTGAGGCCCTTGGCCAAGGGACCAGAGAAGCAGTTGGCACTGGAGTCAGGCAGGTTCCAGGCTTT GGCGTAGCAGATGCTTTGGGCAACAGGGTCGGGGAAGCAGCCCATGCTCTGGGAAACACTGGGCACGAGATTGGCAGACAGGCAGAAGAT GTCATTCGACACGGAGCAGATGCTGTCCGCGGCTCCTGGCAGGGGGTGCCTGGCCACAATGGTGCTTGGGAAACTTCTGGAGGCCATGGC ATCTTTGGCTCTCAAGGTGGCCTTGGAGGCCAGGGCCAGGGCAATCCTGGAGGTCTGGGGACTCCGTGGGTCCACGGATACCCCGGAAAC TCAGCAGGCAGCTTTGGAATGAATCCTCAGGGAGCTCCCTGGGGTCAAGGAGGCAATGGAGGGCCACCAAACTTTGGGACCAACACTCAG GGAGCTGTGGCCCAGCCTGGCTATGGTTCAGTGAGAGCCAGCAACCAGAATGAAGGGTGCACGAATCCCCCACCATCTGGCTCAGGTGGA GGCTCCAGCAACTCTGGGGGAGGCAGCGGCTCACAGTCGGGCAGCAGTGGCAGTGGCAGCAATGGTGACAACAACAATGGCAGCAGCAGT GGTGGCAGCAGCAGTGGCAGCAGCAGTGGCGGCAGCAGTGGCGGCAGCAGTGGTGGCAGCAGTGGCAACAGTGGTGGCAGCAGAGGTGAC AGCGGCAGTGAGTCCTCCTGGGGATCCAGCACCGGCTCCTCCTCCGGCAACCACGGTGGGAGCGGCGGAGGAAATGGACATAAACCCGGG GGCGGACCCCGGAGGCCTGAGCGGCACCTGCCCCCAGCCCCCTGTGGGGCCCCGGGGCCCCCAGAAACCTGCAGGACGGAGCCAGACGGG GCGGGCACCATGAACAAGTTACGGCAGAGCCTGCGGCGGAGGAAGCCAGCCTACGTGCCCGAGGCGTCGCGCCCGCACCAGTGGCAGGCA GACGAGGACGCGGTGCGGAAGGGCACGTGCAGCTTCCCGGTCAGGTACCTGGGTCACGTGGAGGTAGAGGAGTCCCGGGGAATGCACGTG TGTGAAGATGCGGTGAAGAAGCTGAAGGCGATGGGCCGAAAGTCCGTGAAGTCTGTCCTGTGGGTGTCAGCCGATGGGCTCCGAGTGGTG GACGACAAAACCAAGGATCTTCTGGTCGACCAGACCATCGAAAAGGTCTCCTTTTGTGCTCCTGACCGCAACCTGGACAAGGCTTTCTCC TATATCTGTCGTGACGGGACTACCCGCCGCTGGATCTGCCACTGTTTTCTGGCACTGAAGGACTCCGGCGAGAGGCTGAGCCACGCTGTG GGCTGTGCTTTTGCCGCCTGCCTGGAGCGAAAACAGCGACGGGAGAAGGAATGTGGGGTCACGGCCGCCTTCGATGCCAGCCGCACCAGC TTCGCCCGCGAGGGCTCCTTCCGCCTGTCTGGGGGTGGGCGGCCTGCTGAGCGAGAGGCCCCGGACAAGAAGAAAGCAGAGGCAGCAGCT GCCCCCACTGTGGCTCCTGGCCCTGCCCAGCCTGGGCACGTGTCCCCGACACCAGCCACCACATCCCCTGGTGAGAAGGGTGAGGCAGGC ACCCCTGTGGCTGCAGGCACCACTGCGGCCGCCATCCCCCGGCGCCATGCACCCCTGGAGCAGCTGGTTCGCCAGGGCTCCTTCCGTGGG TTCCCAGCACTCAGCCAGAAGAACTCGCCTTTCAAACGGCAGCTGAGCCTACGGCTGAATGAGCTGCCATCCACGCTGCAGCGCCGCACT GACTTCCAGGTGAAGGGCACAGTGCCTGAGATGGAGCCTCCTGGTGCCGGCGACAGTGACAGCATCAACGCTCTGTGCACACAGATCAGT TCATCTTTTGCCAGTGCTGGAGCGCCAGCACCAGGGCCACCACCTGCCACAACAGGGACTTCTGCCTGGGGTGAGCCCTCCGTGCCCCCT GCAGCTGCCTTCCAGCCTGGGCACAAGCGGACACCTTCAGAGGCTGAGCGATGGCTGGAGGAGGTGTCACAGGTGGCCAAGGCCCAGCAG CAGCAGCAGCAGCAACAGCAACAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAAGCAGCCTCAGTGGCCCCAGTGCCCACCATGCCTCCT GCCCTGCAGCCTTTCCCCGCCCCCGTGGGGCCCTTTGACGCTGCACCTGCCCAAGTGGCCGTGTTCCTGCCACCCCCACACATGCAGCCC CCTTTTGTGCCCGCCTACCCGGGCTTGGGCTACCCACCGATGCCCCGGGTGCCCGTGGTGGGCATCACACCCTCACAGATGGTGGCAAAC GCCTTCTGCTCAGCCGCCCAGCTCCAGCCTCAGCCTGCCACTCTGCTTGGGAAAGCTGGGGCCTTCCCGCCCCCTGCCATACCCAGTGCC CCTGGGAGCCAGGCCCGCCCTCGCCCCAATGGGGCCCCCTGGCCCCCTGAGCCAGCGCCTGCCCCAGCTCCAGAGTTGGACCCCTTTGAG GCCCAGTGGGCGGCATTAGAAGGCAAAGCCACTGTAGAGAAACCCTCCAACCCCTTTTCTGGCGACCTGCAAAAGACATTCGAGATTGAA CTGTAGCCCGAGCCGCCCCACCCACTCCATCATCTCCAGGTGCCCCACGCCTGGGGGTGGAGGCACAACCTCTCCCCTAACCCTGCTCCC TGGGGCTGCGCCCCTCAACACCCTCTCAACACCCCCCTCCCTCAACCACCCCGACAACCACTACAGAACCAACATTGTGACGCCCAGGTT GCAACAGGATGGAATTCAGGGACGGACCCAGCCTGGCTAAGGGAACCATTTCACTGCCGGACTTAGGCTGGCAATGCCCCCTTCCCCAAC CCCAGACACAGGGGTTGGCCACAATCCCACTGAATGCCCTTGGTTCACACTCCATTTCCCAGTTTCTGTTGACCCCCACCTTCCAGTGTT GGACAGGATGGAGGGGGGACACTTGCTTAGGGGCTCTCCTGGGCCCCACACCAGTGCCCACCCCAAATCTGGTCGTCTCCTCCCCCCATG CACAGCACAAGCTAAGGGCTGCCCTCTGCCCACACGCTGCGTTCACTGCCAATGCTGTACTCACCTCCATCACCCTCCAACTTTGGGGCC CATGTCTTCCTTGGGCCAAGGTCTCATGGGGGCTAGGGCCAAGTTGGGGGCCCAGGAGGCGGGGAGGGAGGAGGAGGAGAAGATGCGCAG TTACCTCATGTCGGTGCCCGCTGGGGAGGGGTCCGGGAAGAAGGGGAAGGGGTGCCTGGCGGGTACTTTTCTATCTTTTATTTCCAGATT >23252_23252_10_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000440396_NUMBL_chr19_41192900_ENST00000252891_length(amino acids)=983AA_BP=382 MRTGERRLQTQREGGQGVGRRRTEEGTETQSKGGKEETLVGGRHSGERGGWAEMKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGE ALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGVADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADA VRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGY GSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG SSTGSSSGNHGGSGGGNGHKPGGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKG TCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTT RRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAPDKKKAEAAAAPTVAPGP AQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTV PEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQ QQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQL -------------------------------------------------------------- >23252_23252_11_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000443640_NUMBL_chr19_41192900_ENST00000252891_length(transcript)=2721nt_BP=138nt CTGGCCTTCTCCATGCTCGGAATAACTTCCTGCAGCGACCAACAGGCTAAAGAGGGGGAAGGTCTGGAGGGATCCAGCACCGGCTCCTCC TCCGGCAACCACGGTGGGAGCGGCGGAGGAAATGGACATAAACCCGGGGGCGGACCCCGGAGGCCTGAGCGGCACCTGCCCCCAGCCCCC TGTGGGGCCCCGGGGCCCCCAGAAACCTGCAGGACGGAGCCAGACGGGGCGGGCACCATGAACAAGTTACGGCAGAGCCTGCGGCGGAGG AAGCCAGCCTACGTGCCCGAGGCGTCGCGCCCGCACCAGTGGCAGGCAGACGAGGACGCGGTGCGGAAGGGCACGTGCAGCTTCCCGGTC AGGTACCTGGGTCACGTGGAGGTAGAGGAGTCCCGGGGAATGCACGTGTGTGAAGATGCGGTGAAGAAGCTGAAGGCGATGGGCCGAAAG TCCGTGAAGTCTGTCCTGTGGGTGTCAGCCGATGGGCTCCGAGTGGTGGACGACAAAACCAAGGATCTTCTGGTCGACCAGACCATCGAA AAGGTCTCCTTTTGTGCTCCTGACCGCAACCTGGACAAGGCTTTCTCCTATATCTGTCGTGACGGGACTACCCGCCGCTGGATCTGCCAC TGTTTTCTGGCACTGAAGGACTCCGGCGAGAGGCTGAGCCACGCTGTGGGCTGTGCTTTTGCCGCCTGCCTGGAGCGAAAACAGCGACGG GAGAAGGAATGTGGGGTCACGGCCGCCTTCGATGCCAGCCGCACCAGCTTCGCCCGCGAGGGCTCCTTCCGCCTGTCTGGGGGTGGGCGG CCTGCTGAGCGAGAGGCCCCGGACAAGAAGAAAGCAGAGGCAGCAGCTGCCCCCACTGTGGCTCCTGGCCCTGCCCAGCCTGGGCACGTG TCCCCGACACCAGCCACCACATCCCCTGGTGAGAAGGGTGAGGCAGGCACCCCTGTGGCTGCAGGCACCACTGCGGCCGCCATCCCCCGG CGCCATGCACCCCTGGAGCAGCTGGTTCGCCAGGGCTCCTTCCGTGGGTTCCCAGCACTCAGCCAGAAGAACTCGCCTTTCAAACGGCAG CTGAGCCTACGGCTGAATGAGCTGCCATCCACGCTGCAGCGCCGCACTGACTTCCAGGTGAAGGGCACAGTGCCTGAGATGGAGCCTCCT GGTGCCGGCGACAGTGACAGCATCAACGCTCTGTGCACACAGATCAGTTCATCTTTTGCCAGTGCTGGAGCGCCAGCACCAGGGCCACCA CCTGCCACAACAGGGACTTCTGCCTGGGGTGAGCCCTCCGTGCCCCCTGCAGCTGCCTTCCAGCCTGGGCACAAGCGGACACCTTCAGAG GCTGAGCGATGGCTGGAGGAGGTGTCACAGGTGGCCAAGGCCCAGCAGCAGCAGCAGCAGCAACAGCAACAGCAGCAGCAGCAGCAGCAG CAACAGCAGCAAGCAGCCTCAGTGGCCCCAGTGCCCACCATGCCTCCTGCCCTGCAGCCTTTCCCCGCCCCCGTGGGGCCCTTTGACGCT GCACCTGCCCAAGTGGCCGTGTTCCTGCCACCCCCACACATGCAGCCCCCTTTTGTGCCCGCCTACCCGGGCTTGGGCTACCCACCGATG CCCCGGGTGCCCGTGGTGGGCATCACACCCTCACAGATGGTGGCAAACGCCTTCTGCTCAGCCGCCCAGCTCCAGCCTCAGCCTGCCACT CTGCTTGGGAAAGCTGGGGCCTTCCCGCCCCCTGCCATACCCAGTGCCCCTGGGAGCCAGGCCCGCCCTCGCCCCAATGGGGCCCCCTGG CCCCCTGAGCCAGCGCCTGCCCCAGCTCCAGAGTTGGACCCCTTTGAGGCCCAGTGGGCGGCATTAGAAGGCAAAGCCACTGTAGAGAAA CCCTCCAACCCCTTTTCTGGCGACCTGCAAAAGACATTCGAGATTGAACTGTAGCCCGAGCCGCCCCACCCACTCCATCATCTCCAGGTG CCCCACGCCTGGGGGTGGAGGCACAACCTCTCCCCTAACCCTGCTCCCTGGGGCTGCGCCCCTCAACACCCTCTCAACACCCCCCTCCCT CAACCACCCCGACAACCACTACAGAACCAACATTGTGACGCCCAGGTTGCAACAGGATGGAATTCAGGGACGGACCCAGCCTGGCTAAGG GAACCATTTCACTGCCGGACTTAGGCTGGCAATGCCCCCTTCCCCAACCCCAGACACAGGGGTTGGCCACAATCCCACTGAATGCCCTTG GTTCACACTCCATTTCCCAGTTTCTGTTGACCCCCACCTTCCAGTGTTGGACAGGATGGAGGGGGGACACTTGCTTAGGGGCTCTCCTGG GCCCCACACCAGTGCCCACCCCAAATCTGGTCGTCTCCTCCCCCCATGCACAGCACAAGCTAAGGGCTGCCCTCTGCCCACACGCTGCGT TCACTGCCAATGCTGTACTCACCTCCATCACCCTCCAACTTTGGGGCCCATGTCTTCCTTGGGCCAAGGTCTCATGGGGGCTAGGGCCAA GTTGGGGGCCCAGGAGGCGGGGAGGGAGGAGGAGGAGAAGATGCGCAGTTACCTCATGTCGGTGCCCGCTGGGGAGGGGTCCGGGAAGAA GGGGAAGGGGTGCCTGGCGGGTACTTTTCTATCTTTTATTTCCAGATTTTTTTTGTATCTAAACTTGAAGATTTGTATTATACAAGGACA >23252_23252_11_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000443640_NUMBL_chr19_41192900_ENST00000252891_length(amino acids)=647AA_BP=46 LAFSMLGITSCSDQQAKEGEGLEGSSTGSSSGNHGGSGGGNGHKPGGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRR KPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIE KVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGR PAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQ LSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSE AERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPM PRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATVEK -------------------------------------------------------------- >23252_23252_12_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000447113_NUMBL_chr19_41192900_ENST00000252891_length(transcript)=3753nt_BP=1170nt GTGGACTCTGAGAAGCCCAGGCAGTTGAGGACAGGAGAGAGAAGGCTGCAGACCCAGAGGGAGGGAGGACAGGGAGTCGGAAGGAGGAGG ACAGAGGAGGGCACAGAGACGCAGAGCAAGGGCGGCAAGGAGGAGACCCTGGTGGGAGGAAGACACTCTGGAGAGAGAGGGGGCTGGGCA GAGATGAAGTTCCAGGGGCCCCTGGCCTGCCTCCTGCTGGCCCTCTGCCTGGGCAGTGGGGAGGCTGGCCCCCTGCAGAGCGGAGAGGAA AGCACTGGGACAAATATTGGGGAGGCCCTTGGACATGGCCTGGGAGACGCCCTGAGCGAAGGGGTGGGAAAGGCCATTGGCAAAGAGGCC GGAGGGGCAGCTGGCTCTAAAGTCAGTGAGGCCCTTGGCCAAGGGACCAGAGAAGCAGTTGGCACTGGAGTCAGGCAGGTTCCAGGCTTT GGCGTAGCAGATGCTTTGGGCAACAGGGTCGGGGAAGCAGCCCATGCTCTGGGAAACACTGGGCACGAGATTGGCAGACAGGCAGAAGAT GTCATTCGACACGGAGCAGATGCTGTCCGCGGCTCCTGGCAGGGGGTGCCTGGCCACAATGGTGCTTGGGAAACTTCTGGAGGCCATGGC ATCTTTGGCTCTCAAGGTGGCCTTGGAGGCCAGGGCCAGGGCAATCCTGGAGGTCTGGGGACTCCGTGGGTCCACGGATACCCCGGAAAC TCAGCAGGCAGCTTTGGAATGAATCCTCAGGGAGCTCCCTGGGGTCAAGGAGGCAATGGAGGGCCACCAAACTTTGGGACCAACACTCAG GGAGCTGTGGCCCAGCCTGGCTATGGTTCAGTGAGAGCCAGCAACCAGAATGAAGGGTGCACGAATCCCCCACCATCTGGCTCAGGTGGA GGCTCCAGCAACTCTGGGGGAGGCAGCGGCTCACAGTCGGGCAGCAGTGGCAGTGGCAGCAATGGTGACAACAACAATGGCAGCAGCAGT GGTGGCAGCAGCAGTGGCAGCAGCAGTGGCGGCAGCAGTGGCGGCAGCAGTGGTGGCAGCAGTGGCAACAGTGGTGGCAGCAGAGGTGAC AGCGGCAGTGAGTCCTCCTGGGGATCCAGCACCGGCTCCTCCTCCGGCAACCACGGTGGGAGCGGCGGAGGAAATGGACATAAACCCGGG GGCGGACCCCGGAGGCCTGAGCGGCACCTGCCCCCAGCCCCCTGTGGGGCCCCGGGGCCCCCAGAAACCTGCAGGACGGAGCCAGACGGG GCGGGCACCATGAACAAGTTACGGCAGAGCCTGCGGCGGAGGAAGCCAGCCTACGTGCCCGAGGCGTCGCGCCCGCACCAGTGGCAGGCA GACGAGGACGCGGTGCGGAAGGGCACGTGCAGCTTCCCGGTCAGGTACCTGGGTCACGTGGAGGTAGAGGAGTCCCGGGGAATGCACGTG TGTGAAGATGCGGTGAAGAAGCTGAAGGCGATGGGCCGAAAGTCCGTGAAGTCTGTCCTGTGGGTGTCAGCCGATGGGCTCCGAGTGGTG GACGACAAAACCAAGGATCTTCTGGTCGACCAGACCATCGAAAAGGTCTCCTTTTGTGCTCCTGACCGCAACCTGGACAAGGCTTTCTCC TATATCTGTCGTGACGGGACTACCCGCCGCTGGATCTGCCACTGTTTTCTGGCACTGAAGGACTCCGGCGAGAGGCTGAGCCACGCTGTG GGCTGTGCTTTTGCCGCCTGCCTGGAGCGAAAACAGCGACGGGAGAAGGAATGTGGGGTCACGGCCGCCTTCGATGCCAGCCGCACCAGC TTCGCCCGCGAGGGCTCCTTCCGCCTGTCTGGGGGTGGGCGGCCTGCTGAGCGAGAGGCCCCGGACAAGAAGAAAGCAGAGGCAGCAGCT GCCCCCACTGTGGCTCCTGGCCCTGCCCAGCCTGGGCACGTGTCCCCGACACCAGCCACCACATCCCCTGGTGAGAAGGGTGAGGCAGGC ACCCCTGTGGCTGCAGGCACCACTGCGGCCGCCATCCCCCGGCGCCATGCACCCCTGGAGCAGCTGGTTCGCCAGGGCTCCTTCCGTGGG TTCCCAGCACTCAGCCAGAAGAACTCGCCTTTCAAACGGCAGCTGAGCCTACGGCTGAATGAGCTGCCATCCACGCTGCAGCGCCGCACT GACTTCCAGGTGAAGGGCACAGTGCCTGAGATGGAGCCTCCTGGTGCCGGCGACAGTGACAGCATCAACGCTCTGTGCACACAGATCAGT TCATCTTTTGCCAGTGCTGGAGCGCCAGCACCAGGGCCACCACCTGCCACAACAGGGACTTCTGCCTGGGGTGAGCCCTCCGTGCCCCCT GCAGCTGCCTTCCAGCCTGGGCACAAGCGGACACCTTCAGAGGCTGAGCGATGGCTGGAGGAGGTGTCACAGGTGGCCAAGGCCCAGCAG CAGCAGCAGCAGCAACAGCAACAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAAGCAGCCTCAGTGGCCCCAGTGCCCACCATGCCTCCT GCCCTGCAGCCTTTCCCCGCCCCCGTGGGGCCCTTTGACGCTGCACCTGCCCAAGTGGCCGTGTTCCTGCCACCCCCACACATGCAGCCC CCTTTTGTGCCCGCCTACCCGGGCTTGGGCTACCCACCGATGCCCCGGGTGCCCGTGGTGGGCATCACACCCTCACAGATGGTGGCAAAC GCCTTCTGCTCAGCCGCCCAGCTCCAGCCTCAGCCTGCCACTCTGCTTGGGAAAGCTGGGGCCTTCCCGCCCCCTGCCATACCCAGTGCC CCTGGGAGCCAGGCCCGCCCTCGCCCCAATGGGGCCCCCTGGCCCCCTGAGCCAGCGCCTGCCCCAGCTCCAGAGTTGGACCCCTTTGAG GCCCAGTGGGCGGCATTAGAAGGCAAAGCCACTGTAGAGAAACCCTCCAACCCCTTTTCTGGCGACCTGCAAAAGACATTCGAGATTGAA CTGTAGCCCGAGCCGCCCCACCCACTCCATCATCTCCAGGTGCCCCACGCCTGGGGGTGGAGGCACAACCTCTCCCCTAACCCTGCTCCC TGGGGCTGCGCCCCTCAACACCCTCTCAACACCCCCCTCCCTCAACCACCCCGACAACCACTACAGAACCAACATTGTGACGCCCAGGTT GCAACAGGATGGAATTCAGGGACGGACCCAGCCTGGCTAAGGGAACCATTTCACTGCCGGACTTAGGCTGGCAATGCCCCCTTCCCCAAC CCCAGACACAGGGGTTGGCCACAATCCCACTGAATGCCCTTGGTTCACACTCCATTTCCCAGTTTCTGTTGACCCCCACCTTCCAGTGTT GGACAGGATGGAGGGGGGACACTTGCTTAGGGGCTCTCCTGGGCCCCACACCAGTGCCCACCCCAAATCTGGTCGTCTCCTCCCCCCATG CACAGCACAAGCTAAGGGCTGCCCTCTGCCCACACGCTGCGTTCACTGCCAATGCTGTACTCACCTCCATCACCCTCCAACTTTGGGGCC CATGTCTTCCTTGGGCCAAGGTCTCATGGGGGCTAGGGCCAAGTTGGGGGCCCAGGAGGCGGGGAGGGAGGAGGAGGAGAAGATGCGCAG TTACCTCATGTCGGTGCCCGCTGGGGAGGGGTCCGGGAAGAAGGGGAAGGGGTGCCTGGCGGGTACTTTTCTATCTTTTATTTCCAGATT >23252_23252_12_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000447113_NUMBL_chr19_41192900_ENST00000252891_length(amino acids)=983AA_BP=382 MRTGERRLQTQREGGQGVGRRRTEEGTETQSKGGKEETLVGGRHSGERGGWAEMKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGE ALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFGVADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADA VRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGY GSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG SSTGSSSGNHGGSGGGNGHKPGGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKG TCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTT RRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAPDKKKAEAAAAPTVAPGP AQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTV PEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQ QQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQL -------------------------------------------------------------- >23252_23252_13_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000451297_NUMBL_chr19_41192900_ENST00000252891_length(transcript)=3570nt_BP=987nt ATGAAGTTCCAGGGGCCCCTGGCCTGCCTCCTGCTGGCCCTCTGCCTGGGCAGTGGGGAGGCTGGCCCCCTGCAGAGCGGAGAGGAAAGC ACTGGGACAAATATTGGGGAGGCCCTTGGACATGGCCTGGGAGACGCCCTGAGCGAAGGGGTGGGAAAGGCCATTGGCAAAGAGGCCGGA GGGGCAGCTGGCTCTAAAGTCAGTGAGGCCCTTGGCCAAGGGACCAGAGAAGCAGTTGGCACTGGAGTCAGGCAGGTTCCAGGCTTTGGC GTAGCAGATGCTTTGGGCAACAGGGTCGGGGAAGCAGCCCATGCTCTGGGAAACACTGGGCACGAGATTGGCAGACAGGCAGAAGATGTC ATTCGACACGGAGCAGATGCTGTCCGCGGCTCCTGGCAGGGGGTGCCTGGCCACAATGGTGCTTGGGAAACTTCTGGAGGCCATGGCATC TTTGGCTCTCAAGGTGGCCTTGGAGGCCAGGGCCAGGGCAATCCTGGAGGTCTGGGGACTCCGTGGGTCCACGGATACCCCGGAAACTCA GCAGGCAGCTTTGGAATGAATCCTCAGGGAGCTCCCTGGGGTCAAGGAGGCAATGGAGGGCCACCAAACTTTGGGACCAACACTCAGGGA GCTGTGGCCCAGCCTGGCTATGGTTCAGTGAGAGCCAGCAACCAGAATGAAGGGTGCACGAATCCCCCACCATCTGGCTCAGGTGGAGGC TCCAGCAACTCTGGGGGAGGCAGCGGCTCACAGTCGGGCAGCAGTGGCAGTGGCAGCAATGGTGACAACAACAATGGCAGCAGCAGTGGT GGCAGCAGCAGTGGCAGCAGCAGTGGCGGCAGCAGTGGCGGCAGCAGTGGTGGCAGCAGTGGCAACAGTGGTGGCAGCAGAGGTGACAGC GGCAGTGAGTCCTCCTGGGGATCCAGCACCGGCTCCTCCTCCGGCAACCACGGTGGGAGCGGCGGAGGAAATGGACATAAACCCGGGGGC GGACCCCGGAGGCCTGAGCGGCACCTGCCCCCAGCCCCCTGTGGGGCCCCGGGGCCCCCAGAAACCTGCAGGACGGAGCCAGACGGGGCG GGCACCATGAACAAGTTACGGCAGAGCCTGCGGCGGAGGAAGCCAGCCTACGTGCCCGAGGCGTCGCGCCCGCACCAGTGGCAGGCAGAC GAGGACGCGGTGCGGAAGGGCACGTGCAGCTTCCCGGTCAGGTACCTGGGTCACGTGGAGGTAGAGGAGTCCCGGGGAATGCACGTGTGT GAAGATGCGGTGAAGAAGCTGAAGGCGATGGGCCGAAAGTCCGTGAAGTCTGTCCTGTGGGTGTCAGCCGATGGGCTCCGAGTGGTGGAC GACAAAACCAAGGATCTTCTGGTCGACCAGACCATCGAAAAGGTCTCCTTTTGTGCTCCTGACCGCAACCTGGACAAGGCTTTCTCCTAT ATCTGTCGTGACGGGACTACCCGCCGCTGGATCTGCCACTGTTTTCTGGCACTGAAGGACTCCGGCGAGAGGCTGAGCCACGCTGTGGGC TGTGCTTTTGCCGCCTGCCTGGAGCGAAAACAGCGACGGGAGAAGGAATGTGGGGTCACGGCCGCCTTCGATGCCAGCCGCACCAGCTTC GCCCGCGAGGGCTCCTTCCGCCTGTCTGGGGGTGGGCGGCCTGCTGAGCGAGAGGCCCCGGACAAGAAGAAAGCAGAGGCAGCAGCTGCC CCCACTGTGGCTCCTGGCCCTGCCCAGCCTGGGCACGTGTCCCCGACACCAGCCACCACATCCCCTGGTGAGAAGGGTGAGGCAGGCACC CCTGTGGCTGCAGGCACCACTGCGGCCGCCATCCCCCGGCGCCATGCACCCCTGGAGCAGCTGGTTCGCCAGGGCTCCTTCCGTGGGTTC CCAGCACTCAGCCAGAAGAACTCGCCTTTCAAACGGCAGCTGAGCCTACGGCTGAATGAGCTGCCATCCACGCTGCAGCGCCGCACTGAC TTCCAGGTGAAGGGCACAGTGCCTGAGATGGAGCCTCCTGGTGCCGGCGACAGTGACAGCATCAACGCTCTGTGCACACAGATCAGTTCA TCTTTTGCCAGTGCTGGAGCGCCAGCACCAGGGCCACCACCTGCCACAACAGGGACTTCTGCCTGGGGTGAGCCCTCCGTGCCCCCTGCA GCTGCCTTCCAGCCTGGGCACAAGCGGACACCTTCAGAGGCTGAGCGATGGCTGGAGGAGGTGTCACAGGTGGCCAAGGCCCAGCAGCAG CAGCAGCAGCAACAGCAACAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAAGCAGCCTCAGTGGCCCCAGTGCCCACCATGCCTCCTGCC CTGCAGCCTTTCCCCGCCCCCGTGGGGCCCTTTGACGCTGCACCTGCCCAAGTGGCCGTGTTCCTGCCACCCCCACACATGCAGCCCCCT TTTGTGCCCGCCTACCCGGGCTTGGGCTACCCACCGATGCCCCGGGTGCCCGTGGTGGGCATCACACCCTCACAGATGGTGGCAAACGCC TTCTGCTCAGCCGCCCAGCTCCAGCCTCAGCCTGCCACTCTGCTTGGGAAAGCTGGGGCCTTCCCGCCCCCTGCCATACCCAGTGCCCCT GGGAGCCAGGCCCGCCCTCGCCCCAATGGGGCCCCCTGGCCCCCTGAGCCAGCGCCTGCCCCAGCTCCAGAGTTGGACCCCTTTGAGGCC CAGTGGGCGGCATTAGAAGGCAAAGCCACTGTAGAGAAACCCTCCAACCCCTTTTCTGGCGACCTGCAAAAGACATTCGAGATTGAACTG TAGCCCGAGCCGCCCCACCCACTCCATCATCTCCAGGTGCCCCACGCCTGGGGGTGGAGGCACAACCTCTCCCCTAACCCTGCTCCCTGG GGCTGCGCCCCTCAACACCCTCTCAACACCCCCCTCCCTCAACCACCCCGACAACCACTACAGAACCAACATTGTGACGCCCAGGTTGCA ACAGGATGGAATTCAGGGACGGACCCAGCCTGGCTAAGGGAACCATTTCACTGCCGGACTTAGGCTGGCAATGCCCCCTTCCCCAACCCC AGACACAGGGGTTGGCCACAATCCCACTGAATGCCCTTGGTTCACACTCCATTTCCCAGTTTCTGTTGACCCCCACCTTCCAGTGTTGGA CAGGATGGAGGGGGGACACTTGCTTAGGGGCTCTCCTGGGCCCCACACCAGTGCCCACCCCAAATCTGGTCGTCTCCTCCCCCCATGCAC AGCACAAGCTAAGGGCTGCCCTCTGCCCACACGCTGCGTTCACTGCCAATGCTGTACTCACCTCCATCACCCTCCAACTTTGGGGCCCAT GTCTTCCTTGGGCCAAGGTCTCATGGGGGCTAGGGCCAAGTTGGGGGCCCAGGAGGCGGGGAGGGAGGAGGAGGAGAAGATGCGCAGTTA CCTCATGTCGGTGCCCGCTGGGGAGGGGTCCGGGAAGAAGGGGAAGGGGTGCCTGGCGGGTACTTTTCTATCTTTTATTTCCAGATTTTT >23252_23252_13_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000451297_NUMBL_chr19_41192900_ENST00000252891_length(amino acids)=930AA_BP=329 MKFQGPLACLLLALCLGSGEAGPLQSGEESTGTNIGEALGHGLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGTGVRQVPGFG VADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNS AGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG GSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGGGPRRPERHLPPAPCGAPGPPETCRTEPDGA GTMNKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVD DKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSF AREGSFRLSGGGRPAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGF PALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPA AAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPP FVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEA -------------------------------------------------------------- >23252_23252_14_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000458071_NUMBL_chr19_41192900_ENST00000252891_length(transcript)=2717nt_BP=134nt CCTTCTCCATGCTCGGAATAACTTCCTGCAGCGACCAACAGGCTAAAGAGGGGGAAGGTCTGGAGGGATCCAGCACCGGCTCCTCCTCCG GCAACCACGGTGGGAGCGGCGGAGGAAATGGACATAAACCCGGGGGCGGACCCCGGAGGCCTGAGCGGCACCTGCCCCCAGCCCCCTGTG GGGCCCCGGGGCCCCCAGAAACCTGCAGGACGGAGCCAGACGGGGCGGGCACCATGAACAAGTTACGGCAGAGCCTGCGGCGGAGGAAGC CAGCCTACGTGCCCGAGGCGTCGCGCCCGCACCAGTGGCAGGCAGACGAGGACGCGGTGCGGAAGGGCACGTGCAGCTTCCCGGTCAGGT ACCTGGGTCACGTGGAGGTAGAGGAGTCCCGGGGAATGCACGTGTGTGAAGATGCGGTGAAGAAGCTGAAGGCGATGGGCCGAAAGTCCG TGAAGTCTGTCCTGTGGGTGTCAGCCGATGGGCTCCGAGTGGTGGACGACAAAACCAAGGATCTTCTGGTCGACCAGACCATCGAAAAGG TCTCCTTTTGTGCTCCTGACCGCAACCTGGACAAGGCTTTCTCCTATATCTGTCGTGACGGGACTACCCGCCGCTGGATCTGCCACTGTT TTCTGGCACTGAAGGACTCCGGCGAGAGGCTGAGCCACGCTGTGGGCTGTGCTTTTGCCGCCTGCCTGGAGCGAAAACAGCGACGGGAGA AGGAATGTGGGGTCACGGCCGCCTTCGATGCCAGCCGCACCAGCTTCGCCCGCGAGGGCTCCTTCCGCCTGTCTGGGGGTGGGCGGCCTG CTGAGCGAGAGGCCCCGGACAAGAAGAAAGCAGAGGCAGCAGCTGCCCCCACTGTGGCTCCTGGCCCTGCCCAGCCTGGGCACGTGTCCC CGACACCAGCCACCACATCCCCTGGTGAGAAGGGTGAGGCAGGCACCCCTGTGGCTGCAGGCACCACTGCGGCCGCCATCCCCCGGCGCC ATGCACCCCTGGAGCAGCTGGTTCGCCAGGGCTCCTTCCGTGGGTTCCCAGCACTCAGCCAGAAGAACTCGCCTTTCAAACGGCAGCTGA GCCTACGGCTGAATGAGCTGCCATCCACGCTGCAGCGCCGCACTGACTTCCAGGTGAAGGGCACAGTGCCTGAGATGGAGCCTCCTGGTG CCGGCGACAGTGACAGCATCAACGCTCTGTGCACACAGATCAGTTCATCTTTTGCCAGTGCTGGAGCGCCAGCACCAGGGCCACCACCTG CCACAACAGGGACTTCTGCCTGGGGTGAGCCCTCCGTGCCCCCTGCAGCTGCCTTCCAGCCTGGGCACAAGCGGACACCTTCAGAGGCTG AGCGATGGCTGGAGGAGGTGTCACAGGTGGCCAAGGCCCAGCAGCAGCAGCAGCAGCAACAGCAACAGCAGCAGCAGCAGCAGCAGCAAC AGCAGCAAGCAGCCTCAGTGGCCCCAGTGCCCACCATGCCTCCTGCCCTGCAGCCTTTCCCCGCCCCCGTGGGGCCCTTTGACGCTGCAC CTGCCCAAGTGGCCGTGTTCCTGCCACCCCCACACATGCAGCCCCCTTTTGTGCCCGCCTACCCGGGCTTGGGCTACCCACCGATGCCCC GGGTGCCCGTGGTGGGCATCACACCCTCACAGATGGTGGCAAACGCCTTCTGCTCAGCCGCCCAGCTCCAGCCTCAGCCTGCCACTCTGC TTGGGAAAGCTGGGGCCTTCCCGCCCCCTGCCATACCCAGTGCCCCTGGGAGCCAGGCCCGCCCTCGCCCCAATGGGGCCCCCTGGCCCC CTGAGCCAGCGCCTGCCCCAGCTCCAGAGTTGGACCCCTTTGAGGCCCAGTGGGCGGCATTAGAAGGCAAAGCCACTGTAGAGAAACCCT CCAACCCCTTTTCTGGCGACCTGCAAAAGACATTCGAGATTGAACTGTAGCCCGAGCCGCCCCACCCACTCCATCATCTCCAGGTGCCCC ACGCCTGGGGGTGGAGGCACAACCTCTCCCCTAACCCTGCTCCCTGGGGCTGCGCCCCTCAACACCCTCTCAACACCCCCCTCCCTCAAC CACCCCGACAACCACTACAGAACCAACATTGTGACGCCCAGGTTGCAACAGGATGGAATTCAGGGACGGACCCAGCCTGGCTAAGGGAAC CATTTCACTGCCGGACTTAGGCTGGCAATGCCCCCTTCCCCAACCCCAGACACAGGGGTTGGCCACAATCCCACTGAATGCCCTTGGTTC ACACTCCATTTCCCAGTTTCTGTTGACCCCCACCTTCCAGTGTTGGACAGGATGGAGGGGGGACACTTGCTTAGGGGCTCTCCTGGGCCC CACACCAGTGCCCACCCCAAATCTGGTCGTCTCCTCCCCCCATGCACAGCACAAGCTAAGGGCTGCCCTCTGCCCACACGCTGCGTTCAC TGCCAATGCTGTACTCACCTCCATCACCCTCCAACTTTGGGGCCCATGTCTTCCTTGGGCCAAGGTCTCATGGGGGCTAGGGCCAAGTTG GGGGCCCAGGAGGCGGGGAGGGAGGAGGAGGAGAAGATGCGCAGTTACCTCATGTCGGTGCCCGCTGGGGAGGGGTCCGGGAAGAAGGGG AAGGGGTGCCTGGCGGGTACTTTTCTATCTTTTATTTCCAGATTTTTTTTGTATCTAAACTTGAAGATTTGTATTATACAAGGACAGCCA >23252_23252_14_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000458071_NUMBL_chr19_41192900_ENST00000252891_length(amino acids)=643AA_BP=42 MLGITSCSDQQAKEGEGLEGSSTGSSSGNHGGSGGGNGHKPGGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRRKPAY VPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSF CAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAER EAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLR LNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERW LEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVP VVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATVEKPSNP -------------------------------------------------------------- >23252_23252_15_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000467637_NUMBL_chr19_41192900_ENST00000252891_length(transcript)=2728nt_BP=145nt GCCACACCTGGCCTTCTCCATGCTCGGAATAACTTCCTGCAGCGACCAACAGGCTAAAGAGGGGGAAGGTCTGGAGGGATCCAGCACCGG CTCCTCCTCCGGCAACCACGGTGGGAGCGGCGGAGGAAATGGACATAAACCCGGGGGCGGACCCCGGAGGCCTGAGCGGCACCTGCCCCC AGCCCCCTGTGGGGCCCCGGGGCCCCCAGAAACCTGCAGGACGGAGCCAGACGGGGCGGGCACCATGAACAAGTTACGGCAGAGCCTGCG GCGGAGGAAGCCAGCCTACGTGCCCGAGGCGTCGCGCCCGCACCAGTGGCAGGCAGACGAGGACGCGGTGCGGAAGGGCACGTGCAGCTT CCCGGTCAGGTACCTGGGTCACGTGGAGGTAGAGGAGTCCCGGGGAATGCACGTGTGTGAAGATGCGGTGAAGAAGCTGAAGGCGATGGG CCGAAAGTCCGTGAAGTCTGTCCTGTGGGTGTCAGCCGATGGGCTCCGAGTGGTGGACGACAAAACCAAGGATCTTCTGGTCGACCAGAC CATCGAAAAGGTCTCCTTTTGTGCTCCTGACCGCAACCTGGACAAGGCTTTCTCCTATATCTGTCGTGACGGGACTACCCGCCGCTGGAT CTGCCACTGTTTTCTGGCACTGAAGGACTCCGGCGAGAGGCTGAGCCACGCTGTGGGCTGTGCTTTTGCCGCCTGCCTGGAGCGAAAACA GCGACGGGAGAAGGAATGTGGGGTCACGGCCGCCTTCGATGCCAGCCGCACCAGCTTCGCCCGCGAGGGCTCCTTCCGCCTGTCTGGGGG TGGGCGGCCTGCTGAGCGAGAGGCCCCGGACAAGAAGAAAGCAGAGGCAGCAGCTGCCCCCACTGTGGCTCCTGGCCCTGCCCAGCCTGG GCACGTGTCCCCGACACCAGCCACCACATCCCCTGGTGAGAAGGGTGAGGCAGGCACCCCTGTGGCTGCAGGCACCACTGCGGCCGCCAT CCCCCGGCGCCATGCACCCCTGGAGCAGCTGGTTCGCCAGGGCTCCTTCCGTGGGTTCCCAGCACTCAGCCAGAAGAACTCGCCTTTCAA ACGGCAGCTGAGCCTACGGCTGAATGAGCTGCCATCCACGCTGCAGCGCCGCACTGACTTCCAGGTGAAGGGCACAGTGCCTGAGATGGA GCCTCCTGGTGCCGGCGACAGTGACAGCATCAACGCTCTGTGCACACAGATCAGTTCATCTTTTGCCAGTGCTGGAGCGCCAGCACCAGG GCCACCACCTGCCACAACAGGGACTTCTGCCTGGGGTGAGCCCTCCGTGCCCCCTGCAGCTGCCTTCCAGCCTGGGCACAAGCGGACACC TTCAGAGGCTGAGCGATGGCTGGAGGAGGTGTCACAGGTGGCCAAGGCCCAGCAGCAGCAGCAGCAGCAACAGCAACAGCAGCAGCAGCA GCAGCAGCAACAGCAGCAAGCAGCCTCAGTGGCCCCAGTGCCCACCATGCCTCCTGCCCTGCAGCCTTTCCCCGCCCCCGTGGGGCCCTT TGACGCTGCACCTGCCCAAGTGGCCGTGTTCCTGCCACCCCCACACATGCAGCCCCCTTTTGTGCCCGCCTACCCGGGCTTGGGCTACCC ACCGATGCCCCGGGTGCCCGTGGTGGGCATCACACCCTCACAGATGGTGGCAAACGCCTTCTGCTCAGCCGCCCAGCTCCAGCCTCAGCC TGCCACTCTGCTTGGGAAAGCTGGGGCCTTCCCGCCCCCTGCCATACCCAGTGCCCCTGGGAGCCAGGCCCGCCCTCGCCCCAATGGGGC CCCCTGGCCCCCTGAGCCAGCGCCTGCCCCAGCTCCAGAGTTGGACCCCTTTGAGGCCCAGTGGGCGGCATTAGAAGGCAAAGCCACTGT AGAGAAACCCTCCAACCCCTTTTCTGGCGACCTGCAAAAGACATTCGAGATTGAACTGTAGCCCGAGCCGCCCCACCCACTCCATCATCT CCAGGTGCCCCACGCCTGGGGGTGGAGGCACAACCTCTCCCCTAACCCTGCTCCCTGGGGCTGCGCCCCTCAACACCCTCTCAACACCCC CCTCCCTCAACCACCCCGACAACCACTACAGAACCAACATTGTGACGCCCAGGTTGCAACAGGATGGAATTCAGGGACGGACCCAGCCTG GCTAAGGGAACCATTTCACTGCCGGACTTAGGCTGGCAATGCCCCCTTCCCCAACCCCAGACACAGGGGTTGGCCACAATCCCACTGAAT GCCCTTGGTTCACACTCCATTTCCCAGTTTCTGTTGACCCCCACCTTCCAGTGTTGGACAGGATGGAGGGGGGACACTTGCTTAGGGGCT CTCCTGGGCCCCACACCAGTGCCCACCCCAAATCTGGTCGTCTCCTCCCCCCATGCACAGCACAAGCTAAGGGCTGCCCTCTGCCCACAC GCTGCGTTCACTGCCAATGCTGTACTCACCTCCATCACCCTCCAACTTTGGGGCCCATGTCTTCCTTGGGCCAAGGTCTCATGGGGGCTA GGGCCAAGTTGGGGGCCCAGGAGGCGGGGAGGGAGGAGGAGGAGAAGATGCGCAGTTACCTCATGTCGGTGCCCGCTGGGGAGGGGTCCG GGAAGAAGGGGAAGGGGTGCCTGGCGGGTACTTTTCTATCTTTTATTTCCAGATTTTTTTTGTATCTAAACTTGAAGATTTGTATTATAC >23252_23252_15_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000467637_NUMBL_chr19_41192900_ENST00000252891_length(amino acids)=647AA_BP=46 MAFSMLGITSCSDQQAKEGEGLEGSSTGSSSGNHGGSGGGNGHKPGGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRR KPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIE KVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGR PAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQ LSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSE AERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPM PRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATVEK -------------------------------------------------------------- >23252_23252_16_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000480502_NUMBL_chr19_41192900_ENST00000252891_length(transcript)=2741nt_BP=158nt CCGAATACCCTCGGCCACACCTGGCCTTCTCCATGCTCGGAATAACTTCCTGCAGCGACCAACAGGCTAAAGAGGGGGAAGGTCTGGAGG GATCCAGCACCGGCTCCTCCTCCGGCAACCACGGTGGGAGCGGCGGAGGAAATGGACATAAACCCGGGGGCGGACCCCGGAGGCCTGAGC GGCACCTGCCCCCAGCCCCCTGTGGGGCCCCGGGGCCCCCAGAAACCTGCAGGACGGAGCCAGACGGGGCGGGCACCATGAACAAGTTAC GGCAGAGCCTGCGGCGGAGGAAGCCAGCCTACGTGCCCGAGGCGTCGCGCCCGCACCAGTGGCAGGCAGACGAGGACGCGGTGCGGAAGG GCACGTGCAGCTTCCCGGTCAGGTACCTGGGTCACGTGGAGGTAGAGGAGTCCCGGGGAATGCACGTGTGTGAAGATGCGGTGAAGAAGC TGAAGGCGATGGGCCGAAAGTCCGTGAAGTCTGTCCTGTGGGTGTCAGCCGATGGGCTCCGAGTGGTGGACGACAAAACCAAGGATCTTC TGGTCGACCAGACCATCGAAAAGGTCTCCTTTTGTGCTCCTGACCGCAACCTGGACAAGGCTTTCTCCTATATCTGTCGTGACGGGACTA CCCGCCGCTGGATCTGCCACTGTTTTCTGGCACTGAAGGACTCCGGCGAGAGGCTGAGCCACGCTGTGGGCTGTGCTTTTGCCGCCTGCC TGGAGCGAAAACAGCGACGGGAGAAGGAATGTGGGGTCACGGCCGCCTTCGATGCCAGCCGCACCAGCTTCGCCCGCGAGGGCTCCTTCC GCCTGTCTGGGGGTGGGCGGCCTGCTGAGCGAGAGGCCCCGGACAAGAAGAAAGCAGAGGCAGCAGCTGCCCCCACTGTGGCTCCTGGCC CTGCCCAGCCTGGGCACGTGTCCCCGACACCAGCCACCACATCCCCTGGTGAGAAGGGTGAGGCAGGCACCCCTGTGGCTGCAGGCACCA CTGCGGCCGCCATCCCCCGGCGCCATGCACCCCTGGAGCAGCTGGTTCGCCAGGGCTCCTTCCGTGGGTTCCCAGCACTCAGCCAGAAGA ACTCGCCTTTCAAACGGCAGCTGAGCCTACGGCTGAATGAGCTGCCATCCACGCTGCAGCGCCGCACTGACTTCCAGGTGAAGGGCACAG TGCCTGAGATGGAGCCTCCTGGTGCCGGCGACAGTGACAGCATCAACGCTCTGTGCACACAGATCAGTTCATCTTTTGCCAGTGCTGGAG CGCCAGCACCAGGGCCACCACCTGCCACAACAGGGACTTCTGCCTGGGGTGAGCCCTCCGTGCCCCCTGCAGCTGCCTTCCAGCCTGGGC ACAAGCGGACACCTTCAGAGGCTGAGCGATGGCTGGAGGAGGTGTCACAGGTGGCCAAGGCCCAGCAGCAGCAGCAGCAGCAACAGCAAC AGCAGCAGCAGCAGCAGCAGCAACAGCAGCAAGCAGCCTCAGTGGCCCCAGTGCCCACCATGCCTCCTGCCCTGCAGCCTTTCCCCGCCC CCGTGGGGCCCTTTGACGCTGCACCTGCCCAAGTGGCCGTGTTCCTGCCACCCCCACACATGCAGCCCCCTTTTGTGCCCGCCTACCCGG GCTTGGGCTACCCACCGATGCCCCGGGTGCCCGTGGTGGGCATCACACCCTCACAGATGGTGGCAAACGCCTTCTGCTCAGCCGCCCAGC TCCAGCCTCAGCCTGCCACTCTGCTTGGGAAAGCTGGGGCCTTCCCGCCCCCTGCCATACCCAGTGCCCCTGGGAGCCAGGCCCGCCCTC GCCCCAATGGGGCCCCCTGGCCCCCTGAGCCAGCGCCTGCCCCAGCTCCAGAGTTGGACCCCTTTGAGGCCCAGTGGGCGGCATTAGAAG GCAAAGCCACTGTAGAGAAACCCTCCAACCCCTTTTCTGGCGACCTGCAAAAGACATTCGAGATTGAACTGTAGCCCGAGCCGCCCCACC CACTCCATCATCTCCAGGTGCCCCACGCCTGGGGGTGGAGGCACAACCTCTCCCCTAACCCTGCTCCCTGGGGCTGCGCCCCTCAACACC CTCTCAACACCCCCCTCCCTCAACCACCCCGACAACCACTACAGAACCAACATTGTGACGCCCAGGTTGCAACAGGATGGAATTCAGGGA CGGACCCAGCCTGGCTAAGGGAACCATTTCACTGCCGGACTTAGGCTGGCAATGCCCCCTTCCCCAACCCCAGACACAGGGGTTGGCCAC AATCCCACTGAATGCCCTTGGTTCACACTCCATTTCCCAGTTTCTGTTGACCCCCACCTTCCAGTGTTGGACAGGATGGAGGGGGGACAC TTGCTTAGGGGCTCTCCTGGGCCCCACACCAGTGCCCACCCCAAATCTGGTCGTCTCCTCCCCCCATGCACAGCACAAGCTAAGGGCTGC CCTCTGCCCACACGCTGCGTTCACTGCCAATGCTGTACTCACCTCCATCACCCTCCAACTTTGGGGCCCATGTCTTCCTTGGGCCAAGGT CTCATGGGGGCTAGGGCCAAGTTGGGGGCCCAGGAGGCGGGGAGGGAGGAGGAGGAGAAGATGCGCAGTTACCTCATGTCGGTGCCCGCT GGGGAGGGGTCCGGGAAGAAGGGGAAGGGGTGCCTGGCGGGTACTTTTCTATCTTTTATTTCCAGATTTTTTTTGTATCTAAACTTGAAG >23252_23252_16_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000480502_NUMBL_chr19_41192900_ENST00000252891_length(amino acids)=647AA_BP=46 MAFSMLGITSCSDQQAKEGEGLEGSSTGSSSGNHGGSGGGNGHKPGGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRR KPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIE KVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGR PAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQ LSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSE AERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPM PRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATVEK -------------------------------------------------------------- >23252_23252_17_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000488892_NUMBL_chr19_41192900_ENST00000252891_length(transcript)=2757nt_BP=174nt AAATCATTGCGTAGTTCCGAATACCCTCGGCCACACCTGGCCTTCTCCATGCTCGGAATAACTTCCTGCAGCGACCAACAGGCTAAAGAG GGGGAAGGTCTGGAGGGATCCAGCACCGGCTCCTCCTCCGGCAACCACGGTGGGAGCGGCGGAGGAAATGGACATAAACCCGGGGGCGGA CCCCGGAGGCCTGAGCGGCACCTGCCCCCAGCCCCCTGTGGGGCCCCGGGGCCCCCAGAAACCTGCAGGACGGAGCCAGACGGGGCGGGC ACCATGAACAAGTTACGGCAGAGCCTGCGGCGGAGGAAGCCAGCCTACGTGCCCGAGGCGTCGCGCCCGCACCAGTGGCAGGCAGACGAG GACGCGGTGCGGAAGGGCACGTGCAGCTTCCCGGTCAGGTACCTGGGTCACGTGGAGGTAGAGGAGTCCCGGGGAATGCACGTGTGTGAA GATGCGGTGAAGAAGCTGAAGGCGATGGGCCGAAAGTCCGTGAAGTCTGTCCTGTGGGTGTCAGCCGATGGGCTCCGAGTGGTGGACGAC AAAACCAAGGATCTTCTGGTCGACCAGACCATCGAAAAGGTCTCCTTTTGTGCTCCTGACCGCAACCTGGACAAGGCTTTCTCCTATATC TGTCGTGACGGGACTACCCGCCGCTGGATCTGCCACTGTTTTCTGGCACTGAAGGACTCCGGCGAGAGGCTGAGCCACGCTGTGGGCTGT GCTTTTGCCGCCTGCCTGGAGCGAAAACAGCGACGGGAGAAGGAATGTGGGGTCACGGCCGCCTTCGATGCCAGCCGCACCAGCTTCGCC CGCGAGGGCTCCTTCCGCCTGTCTGGGGGTGGGCGGCCTGCTGAGCGAGAGGCCCCGGACAAGAAGAAAGCAGAGGCAGCAGCTGCCCCC ACTGTGGCTCCTGGCCCTGCCCAGCCTGGGCACGTGTCCCCGACACCAGCCACCACATCCCCTGGTGAGAAGGGTGAGGCAGGCACCCCT GTGGCTGCAGGCACCACTGCGGCCGCCATCCCCCGGCGCCATGCACCCCTGGAGCAGCTGGTTCGCCAGGGCTCCTTCCGTGGGTTCCCA GCACTCAGCCAGAAGAACTCGCCTTTCAAACGGCAGCTGAGCCTACGGCTGAATGAGCTGCCATCCACGCTGCAGCGCCGCACTGACTTC CAGGTGAAGGGCACAGTGCCTGAGATGGAGCCTCCTGGTGCCGGCGACAGTGACAGCATCAACGCTCTGTGCACACAGATCAGTTCATCT TTTGCCAGTGCTGGAGCGCCAGCACCAGGGCCACCACCTGCCACAACAGGGACTTCTGCCTGGGGTGAGCCCTCCGTGCCCCCTGCAGCT GCCTTCCAGCCTGGGCACAAGCGGACACCTTCAGAGGCTGAGCGATGGCTGGAGGAGGTGTCACAGGTGGCCAAGGCCCAGCAGCAGCAG CAGCAGCAACAGCAACAGCAGCAGCAGCAGCAGCAGCAACAGCAGCAAGCAGCCTCAGTGGCCCCAGTGCCCACCATGCCTCCTGCCCTG CAGCCTTTCCCCGCCCCCGTGGGGCCCTTTGACGCTGCACCTGCCCAAGTGGCCGTGTTCCTGCCACCCCCACACATGCAGCCCCCTTTT GTGCCCGCCTACCCGGGCTTGGGCTACCCACCGATGCCCCGGGTGCCCGTGGTGGGCATCACACCCTCACAGATGGTGGCAAACGCCTTC TGCTCAGCCGCCCAGCTCCAGCCTCAGCCTGCCACTCTGCTTGGGAAAGCTGGGGCCTTCCCGCCCCCTGCCATACCCAGTGCCCCTGGG AGCCAGGCCCGCCCTCGCCCCAATGGGGCCCCCTGGCCCCCTGAGCCAGCGCCTGCCCCAGCTCCAGAGTTGGACCCCTTTGAGGCCCAG TGGGCGGCATTAGAAGGCAAAGCCACTGTAGAGAAACCCTCCAACCCCTTTTCTGGCGACCTGCAAAAGACATTCGAGATTGAACTGTAG CCCGAGCCGCCCCACCCACTCCATCATCTCCAGGTGCCCCACGCCTGGGGGTGGAGGCACAACCTCTCCCCTAACCCTGCTCCCTGGGGC TGCGCCCCTCAACACCCTCTCAACACCCCCCTCCCTCAACCACCCCGACAACCACTACAGAACCAACATTGTGACGCCCAGGTTGCAACA GGATGGAATTCAGGGACGGACCCAGCCTGGCTAAGGGAACCATTTCACTGCCGGACTTAGGCTGGCAATGCCCCCTTCCCCAACCCCAGA CACAGGGGTTGGCCACAATCCCACTGAATGCCCTTGGTTCACACTCCATTTCCCAGTTTCTGTTGACCCCCACCTTCCAGTGTTGGACAG GATGGAGGGGGGACACTTGCTTAGGGGCTCTCCTGGGCCCCACACCAGTGCCCACCCCAAATCTGGTCGTCTCCTCCCCCCATGCACAGC ACAAGCTAAGGGCTGCCCTCTGCCCACACGCTGCGTTCACTGCCAATGCTGTACTCACCTCCATCACCCTCCAACTTTGGGGCCCATGTC TTCCTTGGGCCAAGGTCTCATGGGGGCTAGGGCCAAGTTGGGGGCCCAGGAGGCGGGGAGGGAGGAGGAGGAGAAGATGCGCAGTTACCT CATGTCGGTGCCCGCTGGGGAGGGGTCCGGGAAGAAGGGGAAGGGGTGCCTGGCGGGTACTTTTCTATCTTTTATTTCCAGATTTTTTTT >23252_23252_17_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000488892_NUMBL_chr19_41192900_ENST00000252891_length(amino acids)=657AA_BP=56 MRSSEYPRPHLAFSMLGITSCSDQQAKEGEGLEGSSTGSSSGNHGGSGGGNGHKPGGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTM NKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDKT KDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFARE GSFRLSGGGRPAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPAL SQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAF QPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVP AYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWA -------------------------------------------------------------- >23252_23252_18_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000602781_NUMBL_chr19_41192900_ENST00000252891_length(transcript)=2710nt_BP=127nt CATGCTCGGAATAACTTCCTGCAGCGACCAACAGGCTAAAGAGGGGGAAGGTCTGGAGGGATCCAGCACCGGCTCCTCCTCCGGCAACCA CGGTGGGAGCGGCGGAGGAAATGGACATAAACCCGGGGGCGGACCCCGGAGGCCTGAGCGGCACCTGCCCCCAGCCCCCTGTGGGGCCCC GGGGCCCCCAGAAACCTGCAGGACGGAGCCAGACGGGGCGGGCACCATGAACAAGTTACGGCAGAGCCTGCGGCGGAGGAAGCCAGCCTA CGTGCCCGAGGCGTCGCGCCCGCACCAGTGGCAGGCAGACGAGGACGCGGTGCGGAAGGGCACGTGCAGCTTCCCGGTCAGGTACCTGGG TCACGTGGAGGTAGAGGAGTCCCGGGGAATGCACGTGTGTGAAGATGCGGTGAAGAAGCTGAAGGCGATGGGCCGAAAGTCCGTGAAGTC TGTCCTGTGGGTGTCAGCCGATGGGCTCCGAGTGGTGGACGACAAAACCAAGGATCTTCTGGTCGACCAGACCATCGAAAAGGTCTCCTT TTGTGCTCCTGACCGCAACCTGGACAAGGCTTTCTCCTATATCTGTCGTGACGGGACTACCCGCCGCTGGATCTGCCACTGTTTTCTGGC ACTGAAGGACTCCGGCGAGAGGCTGAGCCACGCTGTGGGCTGTGCTTTTGCCGCCTGCCTGGAGCGAAAACAGCGACGGGAGAAGGAATG TGGGGTCACGGCCGCCTTCGATGCCAGCCGCACCAGCTTCGCCCGCGAGGGCTCCTTCCGCCTGTCTGGGGGTGGGCGGCCTGCTGAGCG AGAGGCCCCGGACAAGAAGAAAGCAGAGGCAGCAGCTGCCCCCACTGTGGCTCCTGGCCCTGCCCAGCCTGGGCACGTGTCCCCGACACC AGCCACCACATCCCCTGGTGAGAAGGGTGAGGCAGGCACCCCTGTGGCTGCAGGCACCACTGCGGCCGCCATCCCCCGGCGCCATGCACC CCTGGAGCAGCTGGTTCGCCAGGGCTCCTTCCGTGGGTTCCCAGCACTCAGCCAGAAGAACTCGCCTTTCAAACGGCAGCTGAGCCTACG GCTGAATGAGCTGCCATCCACGCTGCAGCGCCGCACTGACTTCCAGGTGAAGGGCACAGTGCCTGAGATGGAGCCTCCTGGTGCCGGCGA CAGTGACAGCATCAACGCTCTGTGCACACAGATCAGTTCATCTTTTGCCAGTGCTGGAGCGCCAGCACCAGGGCCACCACCTGCCACAAC AGGGACTTCTGCCTGGGGTGAGCCCTCCGTGCCCCCTGCAGCTGCCTTCCAGCCTGGGCACAAGCGGACACCTTCAGAGGCTGAGCGATG GCTGGAGGAGGTGTCACAGGTGGCCAAGGCCCAGCAGCAGCAGCAGCAGCAACAGCAACAGCAGCAGCAGCAGCAGCAGCAACAGCAGCA AGCAGCCTCAGTGGCCCCAGTGCCCACCATGCCTCCTGCCCTGCAGCCTTTCCCCGCCCCCGTGGGGCCCTTTGACGCTGCACCTGCCCA AGTGGCCGTGTTCCTGCCACCCCCACACATGCAGCCCCCTTTTGTGCCCGCCTACCCGGGCTTGGGCTACCCACCGATGCCCCGGGTGCC CGTGGTGGGCATCACACCCTCACAGATGGTGGCAAACGCCTTCTGCTCAGCCGCCCAGCTCCAGCCTCAGCCTGCCACTCTGCTTGGGAA AGCTGGGGCCTTCCCGCCCCCTGCCATACCCAGTGCCCCTGGGAGCCAGGCCCGCCCTCGCCCCAATGGGGCCCCCTGGCCCCCTGAGCC AGCGCCTGCCCCAGCTCCAGAGTTGGACCCCTTTGAGGCCCAGTGGGCGGCATTAGAAGGCAAAGCCACTGTAGAGAAACCCTCCAACCC CTTTTCTGGCGACCTGCAAAAGACATTCGAGATTGAACTGTAGCCCGAGCCGCCCCACCCACTCCATCATCTCCAGGTGCCCCACGCCTG GGGGTGGAGGCACAACCTCTCCCCTAACCCTGCTCCCTGGGGCTGCGCCCCTCAACACCCTCTCAACACCCCCCTCCCTCAACCACCCCG ACAACCACTACAGAACCAACATTGTGACGCCCAGGTTGCAACAGGATGGAATTCAGGGACGGACCCAGCCTGGCTAAGGGAACCATTTCA CTGCCGGACTTAGGCTGGCAATGCCCCCTTCCCCAACCCCAGACACAGGGGTTGGCCACAATCCCACTGAATGCCCTTGGTTCACACTCC ATTTCCCAGTTTCTGTTGACCCCCACCTTCCAGTGTTGGACAGGATGGAGGGGGGACACTTGCTTAGGGGCTCTCCTGGGCCCCACACCA GTGCCCACCCCAAATCTGGTCGTCTCCTCCCCCCATGCACAGCACAAGCTAAGGGCTGCCCTCTGCCCACACGCTGCGTTCACTGCCAAT GCTGTACTCACCTCCATCACCCTCCAACTTTGGGGCCCATGTCTTCCTTGGGCCAAGGTCTCATGGGGGCTAGGGCCAAGTTGGGGGCCC AGGAGGCGGGGAGGGAGGAGGAGGAGAAGATGCGCAGTTACCTCATGTCGGTGCCCGCTGGGGAGGGGTCCGGGAAGAAGGGGAAGGGGT GCCTGGCGGGTACTTTTCTATCTTTTATTTCCAGATTTTTTTTGTATCTAAACTTGAAGATTTGTATTATACAAGGACAGCCAATAAAGG >23252_23252_18_DMKN-NUMBL_DMKN_chr19_36001086_ENST00000602781_NUMBL_chr19_41192900_ENST00000252891_length(amino acids)=643AA_BP=42 MLGITSCSDQQAKEGEGLEGSSTGSSSGNHGGSGGGNGHKPGGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRRKPAY VPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSF CAPDRNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAER EAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLR LNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERW LEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVP VVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATVEKPSNP -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for DMKN-NUMBL |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for DMKN-NUMBL |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for DMKN-NUMBL |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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