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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DMXL2-GCOM1 (FusionGDB2 ID:23283)

Fusion Gene Summary for DMXL2-GCOM1

check button Fusion gene summary
Fusion gene informationFusion gene name: DMXL2-GCOM1
Fusion gene ID: 23283
HgeneTgene
Gene symbol

DMXL2

GCOM1

Gene ID

23312

100820829

Gene nameDmx like 2myocardial zonula adherens protein
SynonymsDFNA71|EIEE81|PEPNS|RC3GCOM1|Gup|MYOZAP
Cytomap

15q21.2

15q21.3

Type of geneprotein-codingprotein-coding
DescriptiondmX-like protein 2rabconnectin-3myocardial zonula adherens proteinGRINL1A complex locus upstreamGRINL1A upstream proteinmyocardial intercalated disc proteinmyocardium-enriched ZO1-associated proteinmyocardium-enriched zonula adherens proteinmyocardium-enriched zonula occludens-1-a
Modification date2020031320200313
UniProtAcc

Q8TDJ6

.
Ensembl transtripts involved in fusion geneENST00000251076, ENST00000449909, 
ENST00000543779, ENST00000560421, 
ENST00000380561, ENST00000380568, 
ENST00000484300, ENST00000572390, 
ENST00000587652, ENST00000380560, 
ENST00000380569, ENST00000396180, 
ENST00000574161, 
Fusion gene scores* DoF score10 X 8 X 6=4804 X 4 X 2=32
# samples 94
** MAII scorelog2(9/480*10)=-2.41503749927884
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/32*10)=0.321928094887362
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: DMXL2 [Title/Abstract] AND GCOM1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDMXL2(51914656)-GCOM1(57953648), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across DMXL2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across GCOM1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-28-2513-01ADMXL2chr15

51914656

-GCOM1chr15

57953648

+


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Fusion Gene ORF analysis for DMXL2-GCOM1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000251076ENST00000380561DMXL2chr15

51914656

-GCOM1chr15

57953648

+
5CDS-intronENST00000251076ENST00000380568DMXL2chr15

51914656

-GCOM1chr15

57953648

+
5CDS-intronENST00000251076ENST00000484300DMXL2chr15

51914656

-GCOM1chr15

57953648

+
5CDS-intronENST00000251076ENST00000572390DMXL2chr15

51914656

-GCOM1chr15

57953648

+
5CDS-intronENST00000251076ENST00000587652DMXL2chr15

51914656

-GCOM1chr15

57953648

+
5CDS-intronENST00000449909ENST00000380561DMXL2chr15

51914656

-GCOM1chr15

57953648

+
5CDS-intronENST00000449909ENST00000380568DMXL2chr15

51914656

-GCOM1chr15

57953648

+
5CDS-intronENST00000449909ENST00000484300DMXL2chr15

51914656

-GCOM1chr15

57953648

+
5CDS-intronENST00000449909ENST00000572390DMXL2chr15

51914656

-GCOM1chr15

57953648

+
5CDS-intronENST00000449909ENST00000587652DMXL2chr15

51914656

-GCOM1chr15

57953648

+
5CDS-intronENST00000543779ENST00000380561DMXL2chr15

51914656

-GCOM1chr15

57953648

+
5CDS-intronENST00000543779ENST00000380568DMXL2chr15

51914656

-GCOM1chr15

57953648

+
5CDS-intronENST00000543779ENST00000484300DMXL2chr15

51914656

-GCOM1chr15

57953648

+
5CDS-intronENST00000543779ENST00000572390DMXL2chr15

51914656

-GCOM1chr15

57953648

+
5CDS-intronENST00000543779ENST00000587652DMXL2chr15

51914656

-GCOM1chr15

57953648

+
In-frameENST00000251076ENST00000380560DMXL2chr15

51914656

-GCOM1chr15

57953648

+
In-frameENST00000251076ENST00000380569DMXL2chr15

51914656

-GCOM1chr15

57953648

+
In-frameENST00000251076ENST00000396180DMXL2chr15

51914656

-GCOM1chr15

57953648

+
In-frameENST00000251076ENST00000574161DMXL2chr15

51914656

-GCOM1chr15

57953648

+
In-frameENST00000449909ENST00000380560DMXL2chr15

51914656

-GCOM1chr15

57953648

+
In-frameENST00000449909ENST00000380569DMXL2chr15

51914656

-GCOM1chr15

57953648

+
In-frameENST00000449909ENST00000396180DMXL2chr15

51914656

-GCOM1chr15

57953648

+
In-frameENST00000449909ENST00000574161DMXL2chr15

51914656

-GCOM1chr15

57953648

+
In-frameENST00000543779ENST00000380560DMXL2chr15

51914656

-GCOM1chr15

57953648

+
In-frameENST00000543779ENST00000380569DMXL2chr15

51914656

-GCOM1chr15

57953648

+
In-frameENST00000543779ENST00000396180DMXL2chr15

51914656

-GCOM1chr15

57953648

+
In-frameENST00000543779ENST00000574161DMXL2chr15

51914656

-GCOM1chr15

57953648

+
intron-3CDSENST00000560421ENST00000380560DMXL2chr15

51914656

-GCOM1chr15

57953648

+
intron-3CDSENST00000560421ENST00000380569DMXL2chr15

51914656

-GCOM1chr15

57953648

+
intron-3CDSENST00000560421ENST00000396180DMXL2chr15

51914656

-GCOM1chr15

57953648

+
intron-3CDSENST00000560421ENST00000574161DMXL2chr15

51914656

-GCOM1chr15

57953648

+
intron-intronENST00000560421ENST00000380561DMXL2chr15

51914656

-GCOM1chr15

57953648

+
intron-intronENST00000560421ENST00000380568DMXL2chr15

51914656

-GCOM1chr15

57953648

+
intron-intronENST00000560421ENST00000484300DMXL2chr15

51914656

-GCOM1chr15

57953648

+
intron-intronENST00000560421ENST00000572390DMXL2chr15

51914656

-GCOM1chr15

57953648

+
intron-intronENST00000560421ENST00000587652DMXL2chr15

51914656

-GCOM1chr15

57953648

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000251076DMXL2chr1551914656-ENST00000380569GCOM1chr1557953648+975375288908206
ENST00000251076DMXL2chr1551914656-ENST00000396180GCOM1chr1557953648+657375288656122
ENST00000251076DMXL2chr1551914656-ENST00000380560GCOM1chr1557953648+657375288656122
ENST00000251076DMXL2chr1551914656-ENST00000574161GCOM1chr1557953648+15213751250861129
ENST00000543779DMXL2chr1551914656-ENST00000380569GCOM1chr1557953648+77717790710206
ENST00000543779DMXL2chr1551914656-ENST00000396180GCOM1chr1557953648+45917790458122
ENST00000543779DMXL2chr1551914656-ENST00000380560GCOM1chr1557953648+45917790458122
ENST00000543779DMXL2chr1551914656-ENST00000574161GCOM1chr1557953648+13231771052663129
ENST00000449909DMXL2chr1551914656-ENST00000380569GCOM1chr1557953648+77717790710206
ENST00000449909DMXL2chr1551914656-ENST00000396180GCOM1chr1557953648+45917790458122
ENST00000449909DMXL2chr1551914656-ENST00000380560GCOM1chr1557953648+45917790458122
ENST00000449909DMXL2chr1551914656-ENST00000574161GCOM1chr1557953648+13231771052663129

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000251076ENST00000380569DMXL2chr1551914656-GCOM1chr1557953648+0.0049067540.9950932
ENST00000251076ENST00000396180DMXL2chr1551914656-GCOM1chr1557953648+0.0284636060.97153646
ENST00000251076ENST00000380560DMXL2chr1551914656-GCOM1chr1557953648+0.0284636060.97153646
ENST00000251076ENST00000574161DMXL2chr1551914656-GCOM1chr1557953648+0.0219016170.9780984
ENST00000543779ENST00000380569DMXL2chr1551914656-GCOM1chr1557953648+0.0046537540.99534625
ENST00000543779ENST00000396180DMXL2chr1551914656-GCOM1chr1557953648+0.025515250.9744847
ENST00000543779ENST00000380560DMXL2chr1551914656-GCOM1chr1557953648+0.025515250.9744847
ENST00000543779ENST00000574161DMXL2chr1551914656-GCOM1chr1557953648+0.017072510.9829275
ENST00000449909ENST00000380569DMXL2chr1551914656-GCOM1chr1557953648+0.0046537540.99534625
ENST00000449909ENST00000396180DMXL2chr1551914656-GCOM1chr1557953648+0.025515250.9744847
ENST00000449909ENST00000380560DMXL2chr1551914656-GCOM1chr1557953648+0.025515250.9744847
ENST00000449909ENST00000574161DMXL2chr1551914656-GCOM1chr1557953648+0.017072510.9829275

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Fusion Genomic Features for DMXL2-GCOM1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DMXL2chr1551914655-GCOM1chr1557953647+3.08E-081
DMXL2chr1551914655-GCOM1chr1557953647+3.08E-081

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for DMXL2-GCOM1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:51914656/chr15:57953648)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DMXL2

Q8TDJ6

.
FUNCTION: May serve as a scaffold protein for MADD and RAB3GA on synaptic vesicles (PubMed:11809763). Plays a role in the brain as a key controller of neuronal and endocrine homeostatic processes (By similarity). {ECO:0000250|UniProtKB:Q8BPN8, ECO:0000269|PubMed:11809763}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDMXL2chr15:51914656chr15:57953648ENST00000251076-1432122_2153293037.0Coiled coilOntology_term=ECO:0000255
HgeneDMXL2chr15:51914656chr15:57953648ENST00000449909-1412122_2153292401.0Coiled coilOntology_term=ECO:0000255
HgeneDMXL2chr15:51914656chr15:57953648ENST00000543779-1432122_2153293038.0Coiled coilOntology_term=ECO:0000255
HgeneDMXL2chr15:51914656chr15:57953648ENST00000251076-1431000_1037293037.0RepeatNote=WD 8
HgeneDMXL2chr15:51914656chr15:57953648ENST00000251076-143108_145293037.0RepeatNote=WD 1
HgeneDMXL2chr15:51914656chr15:57953648ENST00000251076-1431163_1204293037.0RepeatNote=WD 9
HgeneDMXL2chr15:51914656chr15:57953648ENST00000251076-1431244_1281293037.0RepeatNote=WD 10
HgeneDMXL2chr15:51914656chr15:57953648ENST00000251076-143167_207293037.0RepeatNote=WD 2
HgeneDMXL2chr15:51914656chr15:57953648ENST00000251076-143230_278293037.0RepeatNote=WD 3
HgeneDMXL2chr15:51914656chr15:57953648ENST00000251076-1432761_2800293037.0RepeatNote=WD 11
HgeneDMXL2chr15:51914656chr15:57953648ENST00000251076-1432804_2843293037.0RepeatNote=WD 12
HgeneDMXL2chr15:51914656chr15:57953648ENST00000251076-1432850_2892293037.0RepeatNote=WD 13
HgeneDMXL2chr15:51914656chr15:57953648ENST00000251076-1432898_2937293037.0RepeatNote=WD 14
HgeneDMXL2chr15:51914656chr15:57953648ENST00000251076-1432940_2979293037.0RepeatNote=WD 15
HgeneDMXL2chr15:51914656chr15:57953648ENST00000251076-1432992_3030293037.0RepeatNote=WD 16
HgeneDMXL2chr15:51914656chr15:57953648ENST00000251076-143492_532293037.0RepeatNote=WD 4
HgeneDMXL2chr15:51914656chr15:57953648ENST00000251076-143595_634293037.0RepeatNote=WD 5
HgeneDMXL2chr15:51914656chr15:57953648ENST00000251076-143751_803293037.0RepeatNote=WD 6
HgeneDMXL2chr15:51914656chr15:57953648ENST00000251076-143878_920293037.0RepeatNote=WD 7
HgeneDMXL2chr15:51914656chr15:57953648ENST00000449909-1411000_1037292401.0RepeatNote=WD 8
HgeneDMXL2chr15:51914656chr15:57953648ENST00000449909-141108_145292401.0RepeatNote=WD 1
HgeneDMXL2chr15:51914656chr15:57953648ENST00000449909-1411163_1204292401.0RepeatNote=WD 9
HgeneDMXL2chr15:51914656chr15:57953648ENST00000449909-1411244_1281292401.0RepeatNote=WD 10
HgeneDMXL2chr15:51914656chr15:57953648ENST00000449909-141167_207292401.0RepeatNote=WD 2
HgeneDMXL2chr15:51914656chr15:57953648ENST00000449909-141230_278292401.0RepeatNote=WD 3
HgeneDMXL2chr15:51914656chr15:57953648ENST00000449909-1412761_2800292401.0RepeatNote=WD 11
HgeneDMXL2chr15:51914656chr15:57953648ENST00000449909-1412804_2843292401.0RepeatNote=WD 12
HgeneDMXL2chr15:51914656chr15:57953648ENST00000449909-1412850_2892292401.0RepeatNote=WD 13
HgeneDMXL2chr15:51914656chr15:57953648ENST00000449909-1412898_2937292401.0RepeatNote=WD 14
HgeneDMXL2chr15:51914656chr15:57953648ENST00000449909-1412940_2979292401.0RepeatNote=WD 15
HgeneDMXL2chr15:51914656chr15:57953648ENST00000449909-1412992_3030292401.0RepeatNote=WD 16
HgeneDMXL2chr15:51914656chr15:57953648ENST00000449909-141492_532292401.0RepeatNote=WD 4
HgeneDMXL2chr15:51914656chr15:57953648ENST00000449909-141595_634292401.0RepeatNote=WD 5
HgeneDMXL2chr15:51914656chr15:57953648ENST00000449909-141751_803292401.0RepeatNote=WD 6
HgeneDMXL2chr15:51914656chr15:57953648ENST00000449909-141878_920292401.0RepeatNote=WD 7
HgeneDMXL2chr15:51914656chr15:57953648ENST00000543779-1431000_1037293038.0RepeatNote=WD 8
HgeneDMXL2chr15:51914656chr15:57953648ENST00000543779-143108_145293038.0RepeatNote=WD 1
HgeneDMXL2chr15:51914656chr15:57953648ENST00000543779-1431163_1204293038.0RepeatNote=WD 9
HgeneDMXL2chr15:51914656chr15:57953648ENST00000543779-1431244_1281293038.0RepeatNote=WD 10
HgeneDMXL2chr15:51914656chr15:57953648ENST00000543779-143167_207293038.0RepeatNote=WD 2
HgeneDMXL2chr15:51914656chr15:57953648ENST00000543779-143230_278293038.0RepeatNote=WD 3
HgeneDMXL2chr15:51914656chr15:57953648ENST00000543779-1432761_2800293038.0RepeatNote=WD 11
HgeneDMXL2chr15:51914656chr15:57953648ENST00000543779-1432804_2843293038.0RepeatNote=WD 12
HgeneDMXL2chr15:51914656chr15:57953648ENST00000543779-1432850_2892293038.0RepeatNote=WD 13
HgeneDMXL2chr15:51914656chr15:57953648ENST00000543779-1432898_2937293038.0RepeatNote=WD 14
HgeneDMXL2chr15:51914656chr15:57953648ENST00000543779-1432940_2979293038.0RepeatNote=WD 15
HgeneDMXL2chr15:51914656chr15:57953648ENST00000543779-1432992_3030293038.0RepeatNote=WD 16
HgeneDMXL2chr15:51914656chr15:57953648ENST00000543779-143492_532293038.0RepeatNote=WD 4
HgeneDMXL2chr15:51914656chr15:57953648ENST00000543779-143595_634293038.0RepeatNote=WD 5
HgeneDMXL2chr15:51914656chr15:57953648ENST00000543779-143751_803293038.0RepeatNote=WD 6
HgeneDMXL2chr15:51914656chr15:57953648ENST00000543779-143878_920293038.0RepeatNote=WD 7


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Fusion Gene Sequence for DMXL2-GCOM1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>23283_23283_1_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000251076_GCOM1_chr15_57953648_ENST00000380560_length(transcript)=657nt_BP=375nt
ACAAGCACCCTTGCCCTCCCGCATTTGTGCGCCGGTGCAGCAGGCAGTGGGAACATCCGGGCATTTCCGCAGCTGAGCGGCGACCCGGGC
GGCGGCGGCGGTCGAGGAGCTCCCATGGCAGGGACGAGGCGGAGGGAAGGCGAAAGGGGGGCGAGGAGTTAAGCCAGAGCCTCCGCGGGG
CGGGTTTCCGAGGGAGGCACAGAGGGAAACGGCTCTCGCAGCCCGAGGAGGGTCAGGCGCGGAGCTTGTCGCACCTCCCGCGCATTCTGT
CCAGCCCGGGCTCCGGAGATGCATCTGCATCAGGTCCTCACCGGAGCTGTCAACCCTGGAGACAACTGCTACTCCGTGGGCAGCGTCGGG
GATGTCCCCTTCACGATTGAATCATTAAAGAAAAAGTTGCAACAGAAACAGCTCTTAATACTGCAGCTTTTAGAAAAGATATCTTTCTTA
GAAGGAGAGAATAATGAACTACAAAGCAGGTTGGACTATTTAACAGAAACCCAGGCCAAGACTGAAGTGGAAACCAGAGAGATAGGAGTG
GGCTGTGATCTTCTACCCAGCCAAACAGGCAGGACTCGTGAAATTGTGATGCCTTCTAGGAACTACACCCCATACACAAGAGTCCTGGAG

>23283_23283_1_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000251076_GCOM1_chr15_57953648_ENST00000380560_length(amino acids)=122AA_BP=27
MHLHQVLTGAVNPGDNCYSVGSVGDVPFTIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQAKTEVETREIGVGCDLLP

--------------------------------------------------------------
>23283_23283_2_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000251076_GCOM1_chr15_57953648_ENST00000380569_length(transcript)=975nt_BP=375nt
ACAAGCACCCTTGCCCTCCCGCATTTGTGCGCCGGTGCAGCAGGCAGTGGGAACATCCGGGCATTTCCGCAGCTGAGCGGCGACCCGGGC
GGCGGCGGCGGTCGAGGAGCTCCCATGGCAGGGACGAGGCGGAGGGAAGGCGAAAGGGGGGCGAGGAGTTAAGCCAGAGCCTCCGCGGGG
CGGGTTTCCGAGGGAGGCACAGAGGGAAACGGCTCTCGCAGCCCGAGGAGGGTCAGGCGCGGAGCTTGTCGCACCTCCCGCGCATTCTGT
CCAGCCCGGGCTCCGGAGATGCATCTGCATCAGGTCCTCACCGGAGCTGTCAACCCTGGAGACAACTGCTACTCCGTGGGCAGCGTCGGG
GATGTCCCCTTCACGATTGAATCATTAAAGAAAAAGTTGCAACAGAAACAGCTCTTAATACTGCAGCTTTTAGAAAAGATATCTTTCTTA
GAAGGAGAGAATAATGAACTACAAAGCAGGTTGGACTATTTAACAGAAACCCAGGCCAAGACTGAAGTGGAAACCAGAGAGATAGGAGTG
GGCTGTGATCTTCTACCCAGGTTACCTTTTCGACAAAATGATTCATCTAGTCATTGCCAGAAGAGTGGGTCTCCTATTTCCTCAGAAGAG
CGGCGGCGCAGGGATAAGCAGCATCTTGATGACATCACAGCAGCTCGGCTTCTACCACTTCACCATATGCCCACGCAGCTGCTCTCCATA
GAAGAATCCTTGGCACTTCAGAAACAGCAGAAACAGAATTATGAGGAGATGCAAGCAAAGCTCGCAGCGCAAAAATTAGCTGAAAGACTG
AATATTAAAATGCGGAGTTATAATCCAGAAGGGGAGTCTTCAGGGAGATACCGAGAAGTAAGGGATGAAGATGACGATTGGTCCTCTGAT

>23283_23283_2_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000251076_GCOM1_chr15_57953648_ENST00000380569_length(amino acids)=206AA_BP=27
MHLHQVLTGAVNPGDNCYSVGSVGDVPFTIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQAKTEVETREIGVGCDLLP
RLPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAERLNIKMRS

--------------------------------------------------------------
>23283_23283_3_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000251076_GCOM1_chr15_57953648_ENST00000396180_length(transcript)=657nt_BP=375nt
ACAAGCACCCTTGCCCTCCCGCATTTGTGCGCCGGTGCAGCAGGCAGTGGGAACATCCGGGCATTTCCGCAGCTGAGCGGCGACCCGGGC
GGCGGCGGCGGTCGAGGAGCTCCCATGGCAGGGACGAGGCGGAGGGAAGGCGAAAGGGGGGCGAGGAGTTAAGCCAGAGCCTCCGCGGGG
CGGGTTTCCGAGGGAGGCACAGAGGGAAACGGCTCTCGCAGCCCGAGGAGGGTCAGGCGCGGAGCTTGTCGCACCTCCCGCGCATTCTGT
CCAGCCCGGGCTCCGGAGATGCATCTGCATCAGGTCCTCACCGGAGCTGTCAACCCTGGAGACAACTGCTACTCCGTGGGCAGCGTCGGG
GATGTCCCCTTCACGATTGAATCATTAAAGAAAAAGTTGCAACAGAAACAGCTCTTAATACTGCAGCTTTTAGAAAAGATATCTTTCTTA
GAAGGAGAGAATAATGAACTACAAAGCAGGTTGGACTATTTAACAGAAACCCAGGCCAAGACTGAAGTGGAAACCAGAGAGATAGGAGTG
GGCTGTGATCTTCTACCCAGCCAAACAGGCAGGACTCGTGAAATTGTGATGCCTTCTAGGAACTACACCCCATACACAAGAGTCCTGGAG

>23283_23283_3_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000251076_GCOM1_chr15_57953648_ENST00000396180_length(amino acids)=122AA_BP=27
MHLHQVLTGAVNPGDNCYSVGSVGDVPFTIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQAKTEVETREIGVGCDLLP

--------------------------------------------------------------
>23283_23283_4_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000251076_GCOM1_chr15_57953648_ENST00000574161_length(transcript)=1521nt_BP=375nt
ACAAGCACCCTTGCCCTCCCGCATTTGTGCGCCGGTGCAGCAGGCAGTGGGAACATCCGGGCATTTCCGCAGCTGAGCGGCGACCCGGGC
GGCGGCGGCGGTCGAGGAGCTCCCATGGCAGGGACGAGGCGGAGGGAAGGCGAAAGGGGGGCGAGGAGTTAAGCCAGAGCCTCCGCGGGG
CGGGTTTCCGAGGGAGGCACAGAGGGAAACGGCTCTCGCAGCCCGAGGAGGGTCAGGCGCGGAGCTTGTCGCACCTCCCGCGCATTCTGT
CCAGCCCGGGCTCCGGAGATGCATCTGCATCAGGTCCTCACCGGAGCTGTCAACCCTGGAGACAACTGCTACTCCGTGGGCAGCGTCGGG
GATGTCCCCTTCACGATTGAATCATTAAAGAAAAAGTTGCAACAGAAACAGCTCTTAATACTGCAGCTTTTAGAAAAGATATCTTTCTTA
GAAGGAGAGAATAATGAACTACAAAGCAGGTTGGACTATTTAACAGAAACCCAGGCCAAGACTGAAGTGGAAACCAGAGAGATAGGAGTG
GGCTGTGATCTTCTACCCAGCCAAACAGGCAGGACTCGTGAAATTGTGATGCCTTCTAGGAACTACACCCCATACACAAGAGTCCTGGAG
TTAACCATGAAGAAAACTCTGACTTAGGCACTCAGAGGCATACACTTTTTACAGATGGACAAAAGCTCTGGAACCCTGTGGCTTCAAATC
CTTTGGGAAGGGTGACTGTTGTTTCCCCTACACACAGTGTAAGCCGGAATGGGAATCGCTGAGGCTCTGATCCACTTCTAAGACAGGAAG
GAAAGTGAAGGCAGAGTGAGCAGGTAAGAGAGGGATATACAAGGTCACATTTCAGACACCCACTCGGCATACCCTGCCGTACTGCATCAT
CATTTGTTTTCTTTGTAGACACTGAAATCCTATCAGGAGGATTCCTTCACAATGTATTTTATTTGCTAGACTTTGGTTGGGAGGGAAAAG
GACATTAATTTGAAGTTTCATGTTATTCATGCCAGGATTGTTTGATAGAGCATGAAGGTTTTGTTTACCCATAAAAGTATTAGAGGCAGC
GTTTCTCTGATACAGAGAGGCCTGTCCACAAGAAGCATGGGCACCCAGCCAAACTTGAACCTGGAAGGGAGGGTTCCCGGCCTGCAGGTG
CTCTTTCCTCTTGGTCCCAAGCATCTGTGCAGGGTCGTGGGAGCCACACTGAGAGACTTGTGTGGGCCAGACAAGCTTCATTCTGATGCG
CTAGTCCCTTGGTTTAATTTGTGCCTTATGCTTTCATTGGACCAGCTGAAATCACTGTATTTATTCAACTAGTGATTTTTTTTTCTTTCT
CACTTTAACTTAAAGAGAATTTTATATGTCTTGGAAATTTAATAATTTAGTGTTCTCAGTATCAATTGGTGTTTTTGTTAAACGAATGAA

>23283_23283_4_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000251076_GCOM1_chr15_57953648_ENST00000574161_length(amino acids)=129AA_BP=
MKLVWPTQVSQCGSHDPAQMLGTKRKEHLQAGNPPFQVQVWLGAHASCGQASLYQRNAASNTFMGKQNLHALSNNPGMNNMKLQINVLFP

--------------------------------------------------------------
>23283_23283_5_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000449909_GCOM1_chr15_57953648_ENST00000380560_length(transcript)=459nt_BP=177nt
ACAGAGGGAAACGGCTCTCGCAGCCCGAGGAGGGTCAGGCGCGGAGCTTGTCGCACCTCCCGCGCATTCTGTCCAGCCCGGGCTCCGGAG
ATGCATCTGCATCAGGTCCTCACCGGAGCTGTCAACCCTGGAGACAACTGCTACTCCGTGGGCAGCGTCGGGGATGTCCCCTTCACGATT
GAATCATTAAAGAAAAAGTTGCAACAGAAACAGCTCTTAATACTGCAGCTTTTAGAAAAGATATCTTTCTTAGAAGGAGAGAATAATGAA
CTACAAAGCAGGTTGGACTATTTAACAGAAACCCAGGCCAAGACTGAAGTGGAAACCAGAGAGATAGGAGTGGGCTGTGATCTTCTACCC
AGCCAAACAGGCAGGACTCGTGAAATTGTGATGCCTTCTAGGAACTACACCCCATACACAAGAGTCCTGGAGTTAACCATGAAGAAAACT

>23283_23283_5_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000449909_GCOM1_chr15_57953648_ENST00000380560_length(amino acids)=122AA_BP=27
MHLHQVLTGAVNPGDNCYSVGSVGDVPFTIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQAKTEVETREIGVGCDLLP

--------------------------------------------------------------
>23283_23283_6_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000449909_GCOM1_chr15_57953648_ENST00000380569_length(transcript)=777nt_BP=177nt
ACAGAGGGAAACGGCTCTCGCAGCCCGAGGAGGGTCAGGCGCGGAGCTTGTCGCACCTCCCGCGCATTCTGTCCAGCCCGGGCTCCGGAG
ATGCATCTGCATCAGGTCCTCACCGGAGCTGTCAACCCTGGAGACAACTGCTACTCCGTGGGCAGCGTCGGGGATGTCCCCTTCACGATT
GAATCATTAAAGAAAAAGTTGCAACAGAAACAGCTCTTAATACTGCAGCTTTTAGAAAAGATATCTTTCTTAGAAGGAGAGAATAATGAA
CTACAAAGCAGGTTGGACTATTTAACAGAAACCCAGGCCAAGACTGAAGTGGAAACCAGAGAGATAGGAGTGGGCTGTGATCTTCTACCC
AGGTTACCTTTTCGACAAAATGATTCATCTAGTCATTGCCAGAAGAGTGGGTCTCCTATTTCCTCAGAAGAGCGGCGGCGCAGGGATAAG
CAGCATCTTGATGACATCACAGCAGCTCGGCTTCTACCACTTCACCATATGCCCACGCAGCTGCTCTCCATAGAAGAATCCTTGGCACTT
CAGAAACAGCAGAAACAGAATTATGAGGAGATGCAAGCAAAGCTCGCAGCGCAAAAATTAGCTGAAAGACTGAATATTAAAATGCGGAGT
TATAATCCAGAAGGGGAGTCTTCAGGGAGATACCGAGAAGTAAGGGATGAAGATGACGATTGGTCCTCTGATGAATTCTGAAGATAATCT

>23283_23283_6_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000449909_GCOM1_chr15_57953648_ENST00000380569_length(amino acids)=206AA_BP=27
MHLHQVLTGAVNPGDNCYSVGSVGDVPFTIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQAKTEVETREIGVGCDLLP
RLPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAERLNIKMRS

--------------------------------------------------------------
>23283_23283_7_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000449909_GCOM1_chr15_57953648_ENST00000396180_length(transcript)=459nt_BP=177nt
ACAGAGGGAAACGGCTCTCGCAGCCCGAGGAGGGTCAGGCGCGGAGCTTGTCGCACCTCCCGCGCATTCTGTCCAGCCCGGGCTCCGGAG
ATGCATCTGCATCAGGTCCTCACCGGAGCTGTCAACCCTGGAGACAACTGCTACTCCGTGGGCAGCGTCGGGGATGTCCCCTTCACGATT
GAATCATTAAAGAAAAAGTTGCAACAGAAACAGCTCTTAATACTGCAGCTTTTAGAAAAGATATCTTTCTTAGAAGGAGAGAATAATGAA
CTACAAAGCAGGTTGGACTATTTAACAGAAACCCAGGCCAAGACTGAAGTGGAAACCAGAGAGATAGGAGTGGGCTGTGATCTTCTACCC
AGCCAAACAGGCAGGACTCGTGAAATTGTGATGCCTTCTAGGAACTACACCCCATACACAAGAGTCCTGGAGTTAACCATGAAGAAAACT

>23283_23283_7_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000449909_GCOM1_chr15_57953648_ENST00000396180_length(amino acids)=122AA_BP=27
MHLHQVLTGAVNPGDNCYSVGSVGDVPFTIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQAKTEVETREIGVGCDLLP

--------------------------------------------------------------
>23283_23283_8_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000449909_GCOM1_chr15_57953648_ENST00000574161_length(transcript)=1323nt_BP=177nt
ACAGAGGGAAACGGCTCTCGCAGCCCGAGGAGGGTCAGGCGCGGAGCTTGTCGCACCTCCCGCGCATTCTGTCCAGCCCGGGCTCCGGAG
ATGCATCTGCATCAGGTCCTCACCGGAGCTGTCAACCCTGGAGACAACTGCTACTCCGTGGGCAGCGTCGGGGATGTCCCCTTCACGATT
GAATCATTAAAGAAAAAGTTGCAACAGAAACAGCTCTTAATACTGCAGCTTTTAGAAAAGATATCTTTCTTAGAAGGAGAGAATAATGAA
CTACAAAGCAGGTTGGACTATTTAACAGAAACCCAGGCCAAGACTGAAGTGGAAACCAGAGAGATAGGAGTGGGCTGTGATCTTCTACCC
AGCCAAACAGGCAGGACTCGTGAAATTGTGATGCCTTCTAGGAACTACACCCCATACACAAGAGTCCTGGAGTTAACCATGAAGAAAACT
CTGACTTAGGCACTCAGAGGCATACACTTTTTACAGATGGACAAAAGCTCTGGAACCCTGTGGCTTCAAATCCTTTGGGAAGGGTGACTG
TTGTTTCCCCTACACACAGTGTAAGCCGGAATGGGAATCGCTGAGGCTCTGATCCACTTCTAAGACAGGAAGGAAAGTGAAGGCAGAGTG
AGCAGGTAAGAGAGGGATATACAAGGTCACATTTCAGACACCCACTCGGCATACCCTGCCGTACTGCATCATCATTTGTTTTCTTTGTAG
ACACTGAAATCCTATCAGGAGGATTCCTTCACAATGTATTTTATTTGCTAGACTTTGGTTGGGAGGGAAAAGGACATTAATTTGAAGTTT
CATGTTATTCATGCCAGGATTGTTTGATAGAGCATGAAGGTTTTGTTTACCCATAAAAGTATTAGAGGCAGCGTTTCTCTGATACAGAGA
GGCCTGTCCACAAGAAGCATGGGCACCCAGCCAAACTTGAACCTGGAAGGGAGGGTTCCCGGCCTGCAGGTGCTCTTTCCTCTTGGTCCC
AAGCATCTGTGCAGGGTCGTGGGAGCCACACTGAGAGACTTGTGTGGGCCAGACAAGCTTCATTCTGATGCGCTAGTCCCTTGGTTTAAT
TTGTGCCTTATGCTTTCATTGGACCAGCTGAAATCACTGTATTTATTCAACTAGTGATTTTTTTTTCTTTCTCACTTTAACTTAAAGAGA
ATTTTATATGTCTTGGAAATTTAATAATTTAGTGTTCTCAGTATCAATTGGTGTTTTTGTTAAACGAATGAATCATCTGTTCATGCATGC

>23283_23283_8_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000449909_GCOM1_chr15_57953648_ENST00000574161_length(amino acids)=129AA_BP=
MKLVWPTQVSQCGSHDPAQMLGTKRKEHLQAGNPPFQVQVWLGAHASCGQASLYQRNAASNTFMGKQNLHALSNNPGMNNMKLQINVLFP

--------------------------------------------------------------
>23283_23283_9_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000543779_GCOM1_chr15_57953648_ENST00000380560_length(transcript)=459nt_BP=177nt
ACAGAGGGAAACGGCTCTCGCAGCCCGAGGAGGGTCAGGCGCGGAGCTTGTCGCACCTCCCGCGCATTCTGTCCAGCCCGGGCTCCGGAG
ATGCATCTGCATCAGGTCCTCACCGGAGCTGTCAACCCTGGAGACAACTGCTACTCCGTGGGCAGCGTCGGGGATGTCCCCTTCACGATT
GAATCATTAAAGAAAAAGTTGCAACAGAAACAGCTCTTAATACTGCAGCTTTTAGAAAAGATATCTTTCTTAGAAGGAGAGAATAATGAA
CTACAAAGCAGGTTGGACTATTTAACAGAAACCCAGGCCAAGACTGAAGTGGAAACCAGAGAGATAGGAGTGGGCTGTGATCTTCTACCC
AGCCAAACAGGCAGGACTCGTGAAATTGTGATGCCTTCTAGGAACTACACCCCATACACAAGAGTCCTGGAGTTAACCATGAAGAAAACT

>23283_23283_9_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000543779_GCOM1_chr15_57953648_ENST00000380560_length(amino acids)=122AA_BP=27
MHLHQVLTGAVNPGDNCYSVGSVGDVPFTIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQAKTEVETREIGVGCDLLP

--------------------------------------------------------------
>23283_23283_10_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000543779_GCOM1_chr15_57953648_ENST00000380569_length(transcript)=777nt_BP=177nt
ACAGAGGGAAACGGCTCTCGCAGCCCGAGGAGGGTCAGGCGCGGAGCTTGTCGCACCTCCCGCGCATTCTGTCCAGCCCGGGCTCCGGAG
ATGCATCTGCATCAGGTCCTCACCGGAGCTGTCAACCCTGGAGACAACTGCTACTCCGTGGGCAGCGTCGGGGATGTCCCCTTCACGATT
GAATCATTAAAGAAAAAGTTGCAACAGAAACAGCTCTTAATACTGCAGCTTTTAGAAAAGATATCTTTCTTAGAAGGAGAGAATAATGAA
CTACAAAGCAGGTTGGACTATTTAACAGAAACCCAGGCCAAGACTGAAGTGGAAACCAGAGAGATAGGAGTGGGCTGTGATCTTCTACCC
AGGTTACCTTTTCGACAAAATGATTCATCTAGTCATTGCCAGAAGAGTGGGTCTCCTATTTCCTCAGAAGAGCGGCGGCGCAGGGATAAG
CAGCATCTTGATGACATCACAGCAGCTCGGCTTCTACCACTTCACCATATGCCCACGCAGCTGCTCTCCATAGAAGAATCCTTGGCACTT
CAGAAACAGCAGAAACAGAATTATGAGGAGATGCAAGCAAAGCTCGCAGCGCAAAAATTAGCTGAAAGACTGAATATTAAAATGCGGAGT
TATAATCCAGAAGGGGAGTCTTCAGGGAGATACCGAGAAGTAAGGGATGAAGATGACGATTGGTCCTCTGATGAATTCTGAAGATAATCT

>23283_23283_10_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000543779_GCOM1_chr15_57953648_ENST00000380569_length(amino acids)=206AA_BP=27
MHLHQVLTGAVNPGDNCYSVGSVGDVPFTIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQAKTEVETREIGVGCDLLP
RLPFRQNDSSSHCQKSGSPISSEERRRRDKQHLDDITAARLLPLHHMPTQLLSIEESLALQKQQKQNYEEMQAKLAAQKLAERLNIKMRS

--------------------------------------------------------------
>23283_23283_11_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000543779_GCOM1_chr15_57953648_ENST00000396180_length(transcript)=459nt_BP=177nt
ACAGAGGGAAACGGCTCTCGCAGCCCGAGGAGGGTCAGGCGCGGAGCTTGTCGCACCTCCCGCGCATTCTGTCCAGCCCGGGCTCCGGAG
ATGCATCTGCATCAGGTCCTCACCGGAGCTGTCAACCCTGGAGACAACTGCTACTCCGTGGGCAGCGTCGGGGATGTCCCCTTCACGATT
GAATCATTAAAGAAAAAGTTGCAACAGAAACAGCTCTTAATACTGCAGCTTTTAGAAAAGATATCTTTCTTAGAAGGAGAGAATAATGAA
CTACAAAGCAGGTTGGACTATTTAACAGAAACCCAGGCCAAGACTGAAGTGGAAACCAGAGAGATAGGAGTGGGCTGTGATCTTCTACCC
AGCCAAACAGGCAGGACTCGTGAAATTGTGATGCCTTCTAGGAACTACACCCCATACACAAGAGTCCTGGAGTTAACCATGAAGAAAACT

>23283_23283_11_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000543779_GCOM1_chr15_57953648_ENST00000396180_length(amino acids)=122AA_BP=27
MHLHQVLTGAVNPGDNCYSVGSVGDVPFTIESLKKKLQQKQLLILQLLEKISFLEGENNELQSRLDYLTETQAKTEVETREIGVGCDLLP

--------------------------------------------------------------
>23283_23283_12_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000543779_GCOM1_chr15_57953648_ENST00000574161_length(transcript)=1323nt_BP=177nt
ACAGAGGGAAACGGCTCTCGCAGCCCGAGGAGGGTCAGGCGCGGAGCTTGTCGCACCTCCCGCGCATTCTGTCCAGCCCGGGCTCCGGAG
ATGCATCTGCATCAGGTCCTCACCGGAGCTGTCAACCCTGGAGACAACTGCTACTCCGTGGGCAGCGTCGGGGATGTCCCCTTCACGATT
GAATCATTAAAGAAAAAGTTGCAACAGAAACAGCTCTTAATACTGCAGCTTTTAGAAAAGATATCTTTCTTAGAAGGAGAGAATAATGAA
CTACAAAGCAGGTTGGACTATTTAACAGAAACCCAGGCCAAGACTGAAGTGGAAACCAGAGAGATAGGAGTGGGCTGTGATCTTCTACCC
AGCCAAACAGGCAGGACTCGTGAAATTGTGATGCCTTCTAGGAACTACACCCCATACACAAGAGTCCTGGAGTTAACCATGAAGAAAACT
CTGACTTAGGCACTCAGAGGCATACACTTTTTACAGATGGACAAAAGCTCTGGAACCCTGTGGCTTCAAATCCTTTGGGAAGGGTGACTG
TTGTTTCCCCTACACACAGTGTAAGCCGGAATGGGAATCGCTGAGGCTCTGATCCACTTCTAAGACAGGAAGGAAAGTGAAGGCAGAGTG
AGCAGGTAAGAGAGGGATATACAAGGTCACATTTCAGACACCCACTCGGCATACCCTGCCGTACTGCATCATCATTTGTTTTCTTTGTAG
ACACTGAAATCCTATCAGGAGGATTCCTTCACAATGTATTTTATTTGCTAGACTTTGGTTGGGAGGGAAAAGGACATTAATTTGAAGTTT
CATGTTATTCATGCCAGGATTGTTTGATAGAGCATGAAGGTTTTGTTTACCCATAAAAGTATTAGAGGCAGCGTTTCTCTGATACAGAGA
GGCCTGTCCACAAGAAGCATGGGCACCCAGCCAAACTTGAACCTGGAAGGGAGGGTTCCCGGCCTGCAGGTGCTCTTTCCTCTTGGTCCC
AAGCATCTGTGCAGGGTCGTGGGAGCCACACTGAGAGACTTGTGTGGGCCAGACAAGCTTCATTCTGATGCGCTAGTCCCTTGGTTTAAT
TTGTGCCTTATGCTTTCATTGGACCAGCTGAAATCACTGTATTTATTCAACTAGTGATTTTTTTTTCTTTCTCACTTTAACTTAAAGAGA
ATTTTATATGTCTTGGAAATTTAATAATTTAGTGTTCTCAGTATCAATTGGTGTTTTTGTTAAACGAATGAATCATCTGTTCATGCATGC

>23283_23283_12_DMXL2-GCOM1_DMXL2_chr15_51914656_ENST00000543779_GCOM1_chr15_57953648_ENST00000574161_length(amino acids)=129AA_BP=
MKLVWPTQVSQCGSHDPAQMLGTKRKEHLQAGNPPFQVQVWLGAHASCGQASLYQRNAASNTFMGKQNLHALSNNPGMNNMKLQINVLFP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for DMXL2-GCOM1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DMXL2-GCOM1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DMXL2-GCOM1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource