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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:DNAJC3-CLDN10 (FusionGDB2 ID:23537) |
Fusion Gene Summary for DNAJC3-CLDN10 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: DNAJC3-CLDN10 | Fusion gene ID: 23537 | Hgene | Tgene | Gene symbol | DNAJC3 | CLDN10 | Gene ID | 5611 | 9071 |
| Gene name | DnaJ heat shock protein family (Hsp40) member C3 | claudin 10 | |
| Synonyms | ACPHD|ERdj6|HP58|P58|P58IPK|PRKRI|p58(IPK) | CPETRL3|HELIX|OSP-L|OSPL | |
| Cytomap | 13q32.1 | 13q32.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | dnaJ homolog subfamily C member 3DnaJ (Hsp40) homolog, subfamily C, member 3ER-resident protein ERdj6endoplasmic reticulum DNA J domain-containing protein 6interferon-induced, double-stranded RNA-activated protein kinase inhibitorprotein kinase inhib | claudin-10OSP-like proteinoligodendrocyte-specific protein-like | |
| Modification date | 20200329 | 20200329 | |
| UniProtAcc | Q13217 | P78369 | |
| Ensembl transtripts involved in fusion gene | ENST00000376795, ENST00000602402, | ENST00000376855, ENST00000299339, ENST00000376873, | |
| Fusion gene scores | * DoF score | 15 X 14 X 8=1680 | 6 X 4 X 5=120 |
| # samples | 18 | 7 | |
| ** MAII score | log2(18/1680*10)=-3.22239242133645 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/120*10)=-0.777607578663552 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: DNAJC3 [Title/Abstract] AND CLDN10 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | DNAJC3(96329591)-CLDN10(96212386), # samples:4 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across DNAJC3 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across CLDN10 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | GBM | TCGA-14-0787-01A | DNAJC3 | chr13 | 96416207 | + | CLDN10 | chr13 | 96212386 | + |
| ChimerDB4 | LUAD | TCGA-44-4112-01A | DNAJC3 | chr13 | 96329591 | - | CLDN10 | chr13 | 96212386 | + |
| ChimerDB4 | LUAD | TCGA-44-4112-01A | DNAJC3 | chr13 | 96329591 | + | CLDN10 | chr13 | 96212386 | + |
| ChimerDB4 | STAD | TCGA-BR-8289-01A | DNAJC3 | chr13 | 96329591 | - | CLDN10 | chr13 | 96212386 | + |
| ChimerDB4 | STAD | TCGA-BR-8289-01A | DNAJC3 | chr13 | 96329591 | + | CLDN10 | chr13 | 96212386 | + |
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Fusion Gene ORF analysis for DNAJC3-CLDN10 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000376795 | ENST00000376855 | DNAJC3 | chr13 | 96416207 | + | CLDN10 | chr13 | 96212386 | + |
| 5CDS-intron | ENST00000376795 | ENST00000376855 | DNAJC3 | chr13 | 96329591 | + | CLDN10 | chr13 | 96212386 | + |
| 5CDS-intron | ENST00000602402 | ENST00000376855 | DNAJC3 | chr13 | 96416207 | + | CLDN10 | chr13 | 96212386 | + |
| 5CDS-intron | ENST00000602402 | ENST00000376855 | DNAJC3 | chr13 | 96329591 | + | CLDN10 | chr13 | 96212386 | + |
| In-frame | ENST00000376795 | ENST00000299339 | DNAJC3 | chr13 | 96416207 | + | CLDN10 | chr13 | 96212386 | + |
| In-frame | ENST00000376795 | ENST00000299339 | DNAJC3 | chr13 | 96329591 | + | CLDN10 | chr13 | 96212386 | + |
| In-frame | ENST00000376795 | ENST00000376873 | DNAJC3 | chr13 | 96416207 | + | CLDN10 | chr13 | 96212386 | + |
| In-frame | ENST00000376795 | ENST00000376873 | DNAJC3 | chr13 | 96329591 | + | CLDN10 | chr13 | 96212386 | + |
| In-frame | ENST00000602402 | ENST00000299339 | DNAJC3 | chr13 | 96416207 | + | CLDN10 | chr13 | 96212386 | + |
| In-frame | ENST00000602402 | ENST00000299339 | DNAJC3 | chr13 | 96329591 | + | CLDN10 | chr13 | 96212386 | + |
| In-frame | ENST00000602402 | ENST00000376873 | DNAJC3 | chr13 | 96416207 | + | CLDN10 | chr13 | 96212386 | + |
| In-frame | ENST00000602402 | ENST00000376873 | DNAJC3 | chr13 | 96329591 | + | CLDN10 | chr13 | 96212386 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000602402 | DNAJC3 | chr13 | 96416207 | + | ENST00000376873 | CLDN10 | chr13 | 96212386 | + | 3404 | 1192 | 45 | 1658 | 537 |
| ENST00000602402 | DNAJC3 | chr13 | 96416207 | + | ENST00000299339 | CLDN10 | chr13 | 96212386 | + | 1892 | 1192 | 45 | 1658 | 537 |
| ENST00000376795 | DNAJC3 | chr13 | 96416207 | + | ENST00000376873 | CLDN10 | chr13 | 96212386 | + | 3232 | 1020 | 26 | 1486 | 486 |
| ENST00000376795 | DNAJC3 | chr13 | 96416207 | + | ENST00000299339 | CLDN10 | chr13 | 96212386 | + | 1720 | 1020 | 26 | 1486 | 486 |
| ENST00000602402 | DNAJC3 | chr13 | 96329591 | + | ENST00000376873 | CLDN10 | chr13 | 96212386 | + | 2411 | 199 | 45 | 665 | 206 |
| ENST00000602402 | DNAJC3 | chr13 | 96329591 | + | ENST00000299339 | CLDN10 | chr13 | 96212386 | + | 899 | 199 | 45 | 665 | 206 |
| ENST00000376795 | DNAJC3 | chr13 | 96329591 | + | ENST00000376873 | CLDN10 | chr13 | 96212386 | + | 2392 | 180 | 26 | 646 | 206 |
| ENST00000376795 | DNAJC3 | chr13 | 96329591 | + | ENST00000299339 | CLDN10 | chr13 | 96212386 | + | 880 | 180 | 26 | 646 | 206 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000602402 | ENST00000376873 | DNAJC3 | chr13 | 96416207 | + | CLDN10 | chr13 | 96212386 | + | 0.000418372 | 0.99958163 |
| ENST00000602402 | ENST00000299339 | DNAJC3 | chr13 | 96416207 | + | CLDN10 | chr13 | 96212386 | + | 0.00063764 | 0.9993624 |
| ENST00000376795 | ENST00000376873 | DNAJC3 | chr13 | 96416207 | + | CLDN10 | chr13 | 96212386 | + | 0.00051304 | 0.9994869 |
| ENST00000376795 | ENST00000299339 | DNAJC3 | chr13 | 96416207 | + | CLDN10 | chr13 | 96212386 | + | 0.000729558 | 0.9992705 |
| ENST00000602402 | ENST00000376873 | DNAJC3 | chr13 | 96329591 | + | CLDN10 | chr13 | 96212386 | + | 0.000662855 | 0.99933714 |
| ENST00000602402 | ENST00000299339 | DNAJC3 | chr13 | 96329591 | + | CLDN10 | chr13 | 96212386 | + | 0.000948947 | 0.99905103 |
| ENST00000376795 | ENST00000376873 | DNAJC3 | chr13 | 96329591 | + | CLDN10 | chr13 | 96212386 | + | 0.000594771 | 0.99940526 |
| ENST00000376795 | ENST00000299339 | DNAJC3 | chr13 | 96329591 | + | CLDN10 | chr13 | 96212386 | + | 0.000821099 | 0.9991788 |
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Fusion Genomic Features for DNAJC3-CLDN10 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| DNAJC3 | chr13 | 96329591 | + | CLDN10 | chr13 | 96212385 | + | 3.83E-07 | 0.99999964 |
| DNAJC3 | chr13 | 96416207 | + | CLDN10 | chr13 | 96212385 | + | 1.49E-07 | 0.9999999 |
| DNAJC3 | chr13 | 96329591 | + | CLDN10 | chr13 | 96212385 | + | 3.83E-07 | 0.99999964 |
| DNAJC3 | chr13 | 96416207 | + | CLDN10 | chr13 | 96212385 | + | 1.49E-07 | 0.9999999 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for DNAJC3-CLDN10 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:96329591/chr13:96212386) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| DNAJC3 | CLDN10 |
| FUNCTION: Involved in the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Acts as a negative regulator of the EIF2AK4/GCN2 kinase activity by preventing the phosphorylation of eIF-2-alpha at 'Ser-52' and hence attenuating general protein synthesis under ER stress, hypothermic and amino acid starving stress conditions (By similarity). Co-chaperone of HSPA8/HSC70, it stimulates its ATPase activity. May inhibit both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2 to catalyze phosphorylation of the EIF2A. May inhibit EIF2AK3/PERK activity. {ECO:0000250|UniProtKB:Q27968, ECO:0000250|UniProtKB:Q91YW3, ECO:0000269|PubMed:12601012, ECO:0000269|PubMed:8576172, ECO:0000269|PubMed:9447982, ECO:0000269|PubMed:9920933}. | FUNCTION: Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Involved in the regulation of paracellular epithelia permeability to ions in multiple organs. It acts as a paracellular ion channel probably forming permselective pores; isoform 1 appears to create pores preferentially permeable to cations and isoform 2 for anions. In sweat glands and in the thick ascending limb (TAL) of Henle's loop in kidney, it controls paracellular sodium permeability which is essential for proper sweat production and renal function (PubMed:19383724, PubMed:28771254, PubMed:28686597). {ECO:0000269|PubMed:19383724, ECO:0000269|PubMed:28686597, ECO:0000269|PubMed:28771254}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | DNAJC3 | chr13:96416207 | chr13:96212386 | ENST00000602402 | + | 9 | 12 | 105_138 | 358 | 505.0 | Repeat | Note=TPR 3 |
| Hgene | DNAJC3 | chr13:96416207 | chr13:96212386 | ENST00000602402 | + | 9 | 12 | 154_187 | 358 | 505.0 | Repeat | Note=TPR 4 |
| Hgene | DNAJC3 | chr13:96416207 | chr13:96212386 | ENST00000602402 | + | 9 | 12 | 189_221 | 358 | 505.0 | Repeat | Note=TPR 5 |
| Hgene | DNAJC3 | chr13:96416207 | chr13:96212386 | ENST00000602402 | + | 9 | 12 | 222_255 | 358 | 505.0 | Repeat | Note=TPR 6 |
| Hgene | DNAJC3 | chr13:96416207 | chr13:96212386 | ENST00000602402 | + | 9 | 12 | 268_301 | 358 | 505.0 | Repeat | Note=TPR 7 |
| Hgene | DNAJC3 | chr13:96416207 | chr13:96212386 | ENST00000602402 | + | 9 | 12 | 306_339 | 358 | 505.0 | Repeat | Note=TPR 8 |
| Hgene | DNAJC3 | chr13:96416207 | chr13:96212386 | ENST00000602402 | + | 9 | 12 | 37_70 | 358 | 505.0 | Repeat | Note=TPR 1 |
| Hgene | DNAJC3 | chr13:96416207 | chr13:96212386 | ENST00000602402 | + | 9 | 12 | 72_104 | 358 | 505.0 | Repeat | Note=TPR 2 |
| Tgene | CLDN10 | chr13:96329591 | chr13:96212386 | ENST00000299339 | 0 | 5 | 102_115 | 73 | 229.0 | Topological domain | Cytoplasmic | |
| Tgene | CLDN10 | chr13:96329591 | chr13:96212386 | ENST00000299339 | 0 | 5 | 137_160 | 73 | 229.0 | Topological domain | Extracellular | |
| Tgene | CLDN10 | chr13:96329591 | chr13:96212386 | ENST00000299339 | 0 | 5 | 182_228 | 73 | 229.0 | Topological domain | Cytoplasmic | |
| Tgene | CLDN10 | chr13:96329591 | chr13:96212386 | ENST00000376873 | 0 | 5 | 102_115 | 71 | 227.0 | Topological domain | Cytoplasmic | |
| Tgene | CLDN10 | chr13:96329591 | chr13:96212386 | ENST00000376873 | 0 | 5 | 137_160 | 71 | 227.0 | Topological domain | Extracellular | |
| Tgene | CLDN10 | chr13:96329591 | chr13:96212386 | ENST00000376873 | 0 | 5 | 182_228 | 71 | 227.0 | Topological domain | Cytoplasmic | |
| Tgene | CLDN10 | chr13:96416207 | chr13:96212386 | ENST00000299339 | 0 | 5 | 102_115 | 73 | 229.0 | Topological domain | Cytoplasmic | |
| Tgene | CLDN10 | chr13:96416207 | chr13:96212386 | ENST00000299339 | 0 | 5 | 137_160 | 73 | 229.0 | Topological domain | Extracellular | |
| Tgene | CLDN10 | chr13:96416207 | chr13:96212386 | ENST00000299339 | 0 | 5 | 182_228 | 73 | 229.0 | Topological domain | Cytoplasmic | |
| Tgene | CLDN10 | chr13:96416207 | chr13:96212386 | ENST00000376873 | 0 | 5 | 102_115 | 71 | 227.0 | Topological domain | Cytoplasmic | |
| Tgene | CLDN10 | chr13:96416207 | chr13:96212386 | ENST00000376873 | 0 | 5 | 137_160 | 71 | 227.0 | Topological domain | Extracellular | |
| Tgene | CLDN10 | chr13:96416207 | chr13:96212386 | ENST00000376873 | 0 | 5 | 182_228 | 71 | 227.0 | Topological domain | Cytoplasmic | |
| Tgene | CLDN10 | chr13:96329591 | chr13:96212386 | ENST00000299339 | 0 | 5 | 116_136 | 73 | 229.0 | Transmembrane | Helical | |
| Tgene | CLDN10 | chr13:96329591 | chr13:96212386 | ENST00000299339 | 0 | 5 | 161_181 | 73 | 229.0 | Transmembrane | Helical | |
| Tgene | CLDN10 | chr13:96329591 | chr13:96212386 | ENST00000299339 | 0 | 5 | 81_101 | 73 | 229.0 | Transmembrane | Helical | |
| Tgene | CLDN10 | chr13:96329591 | chr13:96212386 | ENST00000376873 | 0 | 5 | 116_136 | 71 | 227.0 | Transmembrane | Helical | |
| Tgene | CLDN10 | chr13:96329591 | chr13:96212386 | ENST00000376873 | 0 | 5 | 161_181 | 71 | 227.0 | Transmembrane | Helical | |
| Tgene | CLDN10 | chr13:96329591 | chr13:96212386 | ENST00000376873 | 0 | 5 | 81_101 | 71 | 227.0 | Transmembrane | Helical | |
| Tgene | CLDN10 | chr13:96416207 | chr13:96212386 | ENST00000299339 | 0 | 5 | 116_136 | 73 | 229.0 | Transmembrane | Helical | |
| Tgene | CLDN10 | chr13:96416207 | chr13:96212386 | ENST00000299339 | 0 | 5 | 161_181 | 73 | 229.0 | Transmembrane | Helical | |
| Tgene | CLDN10 | chr13:96416207 | chr13:96212386 | ENST00000299339 | 0 | 5 | 81_101 | 73 | 229.0 | Transmembrane | Helical | |
| Tgene | CLDN10 | chr13:96416207 | chr13:96212386 | ENST00000376873 | 0 | 5 | 116_136 | 71 | 227.0 | Transmembrane | Helical | |
| Tgene | CLDN10 | chr13:96416207 | chr13:96212386 | ENST00000376873 | 0 | 5 | 161_181 | 71 | 227.0 | Transmembrane | Helical | |
| Tgene | CLDN10 | chr13:96416207 | chr13:96212386 | ENST00000376873 | 0 | 5 | 81_101 | 71 | 227.0 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | DNAJC3 | chr13:96329591 | chr13:96212386 | ENST00000602402 | + | 1 | 12 | 394_462 | 27 | 505.0 | Domain | J |
| Hgene | DNAJC3 | chr13:96416207 | chr13:96212386 | ENST00000602402 | + | 9 | 12 | 394_462 | 358 | 505.0 | Domain | J |
| Hgene | DNAJC3 | chr13:96329591 | chr13:96212386 | ENST00000602402 | + | 1 | 12 | 375_393 | 27 | 505.0 | Region | Note=Flexible linker |
| Hgene | DNAJC3 | chr13:96416207 | chr13:96212386 | ENST00000602402 | + | 9 | 12 | 375_393 | 358 | 505.0 | Region | Note=Flexible linker |
| Hgene | DNAJC3 | chr13:96329591 | chr13:96212386 | ENST00000602402 | + | 1 | 12 | 105_138 | 27 | 505.0 | Repeat | Note=TPR 3 |
| Hgene | DNAJC3 | chr13:96329591 | chr13:96212386 | ENST00000602402 | + | 1 | 12 | 154_187 | 27 | 505.0 | Repeat | Note=TPR 4 |
| Hgene | DNAJC3 | chr13:96329591 | chr13:96212386 | ENST00000602402 | + | 1 | 12 | 189_221 | 27 | 505.0 | Repeat | Note=TPR 5 |
| Hgene | DNAJC3 | chr13:96329591 | chr13:96212386 | ENST00000602402 | + | 1 | 12 | 222_255 | 27 | 505.0 | Repeat | Note=TPR 6 |
| Hgene | DNAJC3 | chr13:96329591 | chr13:96212386 | ENST00000602402 | + | 1 | 12 | 268_301 | 27 | 505.0 | Repeat | Note=TPR 7 |
| Hgene | DNAJC3 | chr13:96329591 | chr13:96212386 | ENST00000602402 | + | 1 | 12 | 306_339 | 27 | 505.0 | Repeat | Note=TPR 8 |
| Hgene | DNAJC3 | chr13:96329591 | chr13:96212386 | ENST00000602402 | + | 1 | 12 | 340_373 | 27 | 505.0 | Repeat | Note=TPR 9 |
| Hgene | DNAJC3 | chr13:96329591 | chr13:96212386 | ENST00000602402 | + | 1 | 12 | 37_70 | 27 | 505.0 | Repeat | Note=TPR 1 |
| Hgene | DNAJC3 | chr13:96329591 | chr13:96212386 | ENST00000602402 | + | 1 | 12 | 72_104 | 27 | 505.0 | Repeat | Note=TPR 2 |
| Hgene | DNAJC3 | chr13:96416207 | chr13:96212386 | ENST00000602402 | + | 9 | 12 | 340_373 | 358 | 505.0 | Repeat | Note=TPR 9 |
| Tgene | CLDN10 | chr13:96329591 | chr13:96212386 | ENST00000299339 | 0 | 5 | 22_80 | 73 | 229.0 | Topological domain | Extracellular | |
| Tgene | CLDN10 | chr13:96329591 | chr13:96212386 | ENST00000376873 | 0 | 5 | 22_80 | 71 | 227.0 | Topological domain | Extracellular | |
| Tgene | CLDN10 | chr13:96416207 | chr13:96212386 | ENST00000299339 | 0 | 5 | 22_80 | 73 | 229.0 | Topological domain | Extracellular | |
| Tgene | CLDN10 | chr13:96416207 | chr13:96212386 | ENST00000376873 | 0 | 5 | 22_80 | 71 | 227.0 | Topological domain | Extracellular | |
| Tgene | CLDN10 | chr13:96329591 | chr13:96212386 | ENST00000299339 | 0 | 5 | 1_21 | 73 | 229.0 | Transmembrane | Helical | |
| Tgene | CLDN10 | chr13:96329591 | chr13:96212386 | ENST00000376873 | 0 | 5 | 1_21 | 71 | 227.0 | Transmembrane | Helical | |
| Tgene | CLDN10 | chr13:96416207 | chr13:96212386 | ENST00000299339 | 0 | 5 | 1_21 | 73 | 229.0 | Transmembrane | Helical | |
| Tgene | CLDN10 | chr13:96416207 | chr13:96212386 | ENST00000376873 | 0 | 5 | 1_21 | 71 | 227.0 | Transmembrane | Helical |
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Fusion Gene Sequence for DNAJC3-CLDN10 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >23537_23537_1_DNAJC3-CLDN10_DNAJC3_chr13_96329591_ENST00000376795_CLDN10_chr13_96212386_ENST00000299339_length(transcript)=880nt_BP=180nt CGAGAGCCGACGGCGGGCGGGCGCAGCTGCTGCCGGAGCGCCGGCGCGTGCTGGTGGGCCACACACCTTTCCTCCTCTTCACTCGCGAGC CCTCGGACATGGTGGCCCCCGGCTCCGTGACCAGCCGGCTGGGCTCGGTATTCCCCTTCCTGCTAGTCCTGGTGGATCTGCAGTACGAAG GTTATATACAGGCATGTAGAGGACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCGCTCTTTGGAATGAAGTGTA CCAAAGTCGGAGGCTCCGATAAAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTG GATGTTCCCTATATGCAAACAAAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAGTATGAATTAGGAGCCGCTCTGTTTA TTGGATGGGCAGGAGCCTCACTGTGCATAATTGGTGGTGTCATATTTTGCTTTTCAATATCTGACAACAACAAAACACCCAGATACACAT ACAACGGGGCCACATCTGTCATGTCTTCTCGGACAAAGTATCATGGTGGAGAAGATTTTAAAACAACAAACCCTTCAAAACAGTTTGATA AAAATGCTTATGTCTAAAAGAGCTCGCTGGCAAGCTGCCTCTTGAGTTTGTTATAAAAGCGAACTGTTCACAAAATGATCCCATCAAGGC CCTCCCATAATTAACACTCAAAACTATTTTTAAAATATGCATTTGAAGCATCTGTTGATTGTATGGATGTAAGTGTTCTTACATAGTTAG >23537_23537_1_DNAJC3-CLDN10_DNAJC3_chr13_96329591_ENST00000376795_CLDN10_chr13_96212386_ENST00000299339_length(amino acids)=206AA_BP=25 MLPERRRVLVGHTPFLLFTREPSDMVAPGSVTSRLGSVFPFLLVLVDLQYEGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKA KAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRYTYNGATSVMS -------------------------------------------------------------- >23537_23537_2_DNAJC3-CLDN10_DNAJC3_chr13_96329591_ENST00000376795_CLDN10_chr13_96212386_ENST00000376873_length(transcript)=2392nt_BP=180nt CGAGAGCCGACGGCGGGCGGGCGCAGCTGCTGCCGGAGCGCCGGCGCGTGCTGGTGGGCCACACACCTTTCCTCCTCTTCACTCGCGAGC CCTCGGACATGGTGGCCCCCGGCTCCGTGACCAGCCGGCTGGGCTCGGTATTCCCCTTCCTGCTAGTCCTGGTGGATCTGCAGTACGAAG GTTATATACAGGCATGTAGAGGACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCGCTCTTTGGAATGAAGTGTA CCAAAGTCGGAGGCTCCGATAAAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCAGGGCTGTGCTCAATGACTG GATGTTCCCTATATGCAAACAAAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAGTATGAATTAGGAGCCGCTCTGTTTA TTGGATGGGCAGGAGCCTCACTGTGCATAATTGGTGGTGTCATATTTTGCTTTTCAATATCTGACAACAACAAAACACCCAGATACACAT ACAACGGGGCCACATCTGTCATGTCTTCTCGGACAAAGTATCATGGTGGAGAAGATTTTAAAACAACAAACCCTTCAAAACAGTTTGATA AAAATGCTTATGTCTAAAAGAGCTCGCTGGCAAGCTGCCTCTTGAGTTTGTTATAAAAGCGAACTGTTCACAAAATGATCCCATCAAGGC CCTCCCATAATTAACACTCAAAACTATTTTTAAAATATGCATTTGAAGCATCTGTTGATTGTATGGATGTAAGTGTTCTTACATAGTTAG TTATATACTAATCATTTTCTGTTGTGGCTTTCTATAAAAAATAAACAGTTTATTTACAGGATTTGTAAAATGTTTTCTACATTTATATAG AACATGAAAAGCATTTAGTACCAAAGGTTCAAGAAGTATTCGTACTCTAGCCTTTTTAATCATTCATAGATAGAAGTCTTTGTACCCACT CCTTATGTTTCTTTTCATTCATAAACAGGTGTATAAGGAACAATGTCTTATAAACAGCATGGGGGCAATCTGAGAATATTCCTCAAAAGG TGTCCAGGTTAAATAGACATGTTACTGGCTGCACACAGGCAAATTCTAGTTTGTTTTTTTTAAGTATTCTACAACATTTATTTAAAAAGG TAAATCTTTTTGTTGAAGCAGCAAGTTATCTGGTAGAACTTAACTTCTACAGGATCAGAGAGGATCTTGCTCATTCATGGCCATATCCAC ATGCCCATGGCCACTCAGTAGATTGTTGAAAAAGCAAAGCCACACCATTCTCTTTGATGTATGCAGAGAGTTACGTAGCAGGGGATGTTC TCTGATTTATTCCACTGGCACCATTAGTGAATATTTAGTTGTTTTCATAAACGATGCTGTGATGAAGACTCATGTACATATTTAGCAAAT TTTGGTTTCTTACATGTGCCTGTCATGACTGTAATTCATTATGACTGCTCCAGGAAGGGCTAATGGGGCCAATATATTATTGCCTGTCAT GTGGCACATCCATGTTAAGGGGCTGAGGCGTCCCTGGCACGGAATGCAGAGCCCTGAGCTAGGGCATCAGCAGAAGCTGAGATAGAGATA TTGGTCATGGTTGACTGAGGAGCCAATTAAAACCTGTTTATGCCTAGTGTTCCATTATTGGAACACTAAGCATGTGGGAGTTATTTATAT CCTACTGCTCAAGGTCATCGCCAAGGTGTGATTGGAAAAATTCAAAAAATTGCAACCTCAGGCATAAATGGGTTAAGGACATCCCAAGCC CAAGTGGTACGTGCCTCACTCAGAACTGACGGGCCGAGTTCTATCTAGGTGTGTCTTCCAGAACCTGTTTACGGCTAACTGGATAACTGA GAGACTTGTCATTTCTAAAGACATTTAAGTTGCTCCAGGGATTTCTGAAAAAAGACACAGGCTTCTTCCTAGAGCCAGCCCTATATAACA TGCCCACAAGGGCAACAGTTATCACAGTTCATACACACCTTTCATGTCCTGTCTCACTCACTCCTCACAGCCATCCTAGGAGATACATAT TGTTTTCATCCTGCATTTACAGAAAAAGAAATGAAAACAGAGAGCTTAAATAATTTGCCACAGTAATGTCGAAACTAGGCCTTTGAACCA AGGCAGTCTAGGGTAAAATATAGTTTCAAAGTATGAATAAGAATTGGTATTTGTGTTATCTTTGAGTAAGAAACTGTCCGATATGAATCA CAACGTGGGTGAATGTAGTATTTTCCTGAAGTGTGAAAGACTTAAAAAAAAGAATCACATTGTTCAGAGGTGCTCAATGGAAAGAAAAGG >23537_23537_2_DNAJC3-CLDN10_DNAJC3_chr13_96329591_ENST00000376795_CLDN10_chr13_96212386_ENST00000376873_length(amino acids)=206AA_BP=25 MLPERRRVLVGHTPFLLFTREPSDMVAPGSVTSRLGSVFPFLLVLVDLQYEGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKA KAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRYTYNGATSVMS -------------------------------------------------------------- >23537_23537_3_DNAJC3-CLDN10_DNAJC3_chr13_96329591_ENST00000602402_CLDN10_chr13_96212386_ENST00000299339_length(transcript)=899nt_BP=199nt AGAGCCACTGAGGCCTGAGCGAGAGCCGACGGCGGGCGGGCGCAGCTGCTGCCGGAGCGCCGGCGCGTGCTGGTGGGCCACACACCTTTC CTCCTCTTCACTCGCGAGCCCTCGGACATGGTGGCCCCCGGCTCCGTGACCAGCCGGCTGGGCTCGGTATTCCCCTTCCTGCTAGTCCTG GTGGATCTGCAGTACGAAGGTTATATACAGGCATGTAGAGGACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCG CTCTTTGGAATGAAGTGTACCAAAGTCGGAGGCTCCGATAAAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCA GGGCTGTGCTCAATGACTGGATGTTCCCTATATGCAAACAAAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAGTATGAA TTAGGAGCCGCTCTGTTTATTGGATGGGCAGGAGCCTCACTGTGCATAATTGGTGGTGTCATATTTTGCTTTTCAATATCTGACAACAAC AAAACACCCAGATACACATACAACGGGGCCACATCTGTCATGTCTTCTCGGACAAAGTATCATGGTGGAGAAGATTTTAAAACAACAAAC CCTTCAAAACAGTTTGATAAAAATGCTTATGTCTAAAAGAGCTCGCTGGCAAGCTGCCTCTTGAGTTTGTTATAAAAGCGAACTGTTCAC AAAATGATCCCATCAAGGCCCTCCCATAATTAACACTCAAAACTATTTTTAAAATATGCATTTGAAGCATCTGTTGATTGTATGGATGTA >23537_23537_3_DNAJC3-CLDN10_DNAJC3_chr13_96329591_ENST00000602402_CLDN10_chr13_96212386_ENST00000299339_length(amino acids)=206AA_BP=25 MLPERRRVLVGHTPFLLFTREPSDMVAPGSVTSRLGSVFPFLLVLVDLQYEGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKA KAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRYTYNGATSVMS -------------------------------------------------------------- >23537_23537_4_DNAJC3-CLDN10_DNAJC3_chr13_96329591_ENST00000602402_CLDN10_chr13_96212386_ENST00000376873_length(transcript)=2411nt_BP=199nt AGAGCCACTGAGGCCTGAGCGAGAGCCGACGGCGGGCGGGCGCAGCTGCTGCCGGAGCGCCGGCGCGTGCTGGTGGGCCACACACCTTTC CTCCTCTTCACTCGCGAGCCCTCGGACATGGTGGCCCCCGGCTCCGTGACCAGCCGGCTGGGCTCGGTATTCCCCTTCCTGCTAGTCCTG GTGGATCTGCAGTACGAAGGTTATATACAGGCATGTAGAGGACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTTGCG CTCTTTGGAATGAAGTGTACCAAAGTCGGAGGCTCCGATAAAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTGTCA GGGCTGTGCTCAATGACTGGATGTTCCCTATATGCAAACAAAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAGTATGAA TTAGGAGCCGCTCTGTTTATTGGATGGGCAGGAGCCTCACTGTGCATAATTGGTGGTGTCATATTTTGCTTTTCAATATCTGACAACAAC AAAACACCCAGATACACATACAACGGGGCCACATCTGTCATGTCTTCTCGGACAAAGTATCATGGTGGAGAAGATTTTAAAACAACAAAC CCTTCAAAACAGTTTGATAAAAATGCTTATGTCTAAAAGAGCTCGCTGGCAAGCTGCCTCTTGAGTTTGTTATAAAAGCGAACTGTTCAC AAAATGATCCCATCAAGGCCCTCCCATAATTAACACTCAAAACTATTTTTAAAATATGCATTTGAAGCATCTGTTGATTGTATGGATGTA AGTGTTCTTACATAGTTAGTTATATACTAATCATTTTCTGTTGTGGCTTTCTATAAAAAATAAACAGTTTATTTACAGGATTTGTAAAAT GTTTTCTACATTTATATAGAACATGAAAAGCATTTAGTACCAAAGGTTCAAGAAGTATTCGTACTCTAGCCTTTTTAATCATTCATAGAT AGAAGTCTTTGTACCCACTCCTTATGTTTCTTTTCATTCATAAACAGGTGTATAAGGAACAATGTCTTATAAACAGCATGGGGGCAATCT GAGAATATTCCTCAAAAGGTGTCCAGGTTAAATAGACATGTTACTGGCTGCACACAGGCAAATTCTAGTTTGTTTTTTTTAAGTATTCTA CAACATTTATTTAAAAAGGTAAATCTTTTTGTTGAAGCAGCAAGTTATCTGGTAGAACTTAACTTCTACAGGATCAGAGAGGATCTTGCT CATTCATGGCCATATCCACATGCCCATGGCCACTCAGTAGATTGTTGAAAAAGCAAAGCCACACCATTCTCTTTGATGTATGCAGAGAGT TACGTAGCAGGGGATGTTCTCTGATTTATTCCACTGGCACCATTAGTGAATATTTAGTTGTTTTCATAAACGATGCTGTGATGAAGACTC ATGTACATATTTAGCAAATTTTGGTTTCTTACATGTGCCTGTCATGACTGTAATTCATTATGACTGCTCCAGGAAGGGCTAATGGGGCCA ATATATTATTGCCTGTCATGTGGCACATCCATGTTAAGGGGCTGAGGCGTCCCTGGCACGGAATGCAGAGCCCTGAGCTAGGGCATCAGC AGAAGCTGAGATAGAGATATTGGTCATGGTTGACTGAGGAGCCAATTAAAACCTGTTTATGCCTAGTGTTCCATTATTGGAACACTAAGC ATGTGGGAGTTATTTATATCCTACTGCTCAAGGTCATCGCCAAGGTGTGATTGGAAAAATTCAAAAAATTGCAACCTCAGGCATAAATGG GTTAAGGACATCCCAAGCCCAAGTGGTACGTGCCTCACTCAGAACTGACGGGCCGAGTTCTATCTAGGTGTGTCTTCCAGAACCTGTTTA CGGCTAACTGGATAACTGAGAGACTTGTCATTTCTAAAGACATTTAAGTTGCTCCAGGGATTTCTGAAAAAAGACACAGGCTTCTTCCTA GAGCCAGCCCTATATAACATGCCCACAAGGGCAACAGTTATCACAGTTCATACACACCTTTCATGTCCTGTCTCACTCACTCCTCACAGC CATCCTAGGAGATACATATTGTTTTCATCCTGCATTTACAGAAAAAGAAATGAAAACAGAGAGCTTAAATAATTTGCCACAGTAATGTCG AAACTAGGCCTTTGAACCAAGGCAGTCTAGGGTAAAATATAGTTTCAAAGTATGAATAAGAATTGGTATTTGTGTTATCTTTGAGTAAGA AACTGTCCGATATGAATCACAACGTGGGTGAATGTAGTATTTTCCTGAAGTGTGAAAGACTTAAAAAAAAGAATCACATTGTTCAGAGGT >23537_23537_4_DNAJC3-CLDN10_DNAJC3_chr13_96329591_ENST00000602402_CLDN10_chr13_96212386_ENST00000376873_length(amino acids)=206AA_BP=25 MLPERRRVLVGHTPFLLFTREPSDMVAPGSVTSRLGSVFPFLLVLVDLQYEGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKA KAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRYTYNGATSVMS -------------------------------------------------------------- >23537_23537_5_DNAJC3-CLDN10_DNAJC3_chr13_96416207_ENST00000376795_CLDN10_chr13_96212386_ENST00000299339_length(transcript)=1720nt_BP=1020nt CGAGAGCCGACGGCGGGCGGGCGCAGCTGCTGCCGGAGCGCCGGCGCGTGCTGGTGGGCCACACACCTTTCCTCCTCTTCACTCGCGAGC CCTCGGACATGGTGGCCCCCGGCTCCGTGACCAGCCGGCTGGGCTCGGTATTCCCCTTCCTGCTAGTCCTGGTGGATCTGCAGTACGAAG GTGCTGAATGTGGAGTAAATGCAGATGTTGAGAAACATCTTGAATTGGGCAAGAAATTACTTGCAGCTGGACAGCTAGCTGATGCTTTAT CTCAGTTTCATGCTGCCGTAGATGGTGACCCTGATAACTATATTGCTTATTATCGGAGGGCTACTGTCTTTTTAGCTATGGGCAAATCAA AAGCTGCACTTCCTGATTTAACTAAAGTGATTCAATTGAAGATGGACTTCACTGCAGCAAGATTACAGAGAGGTCACTTATTACTCAAAC AAGGAAAACTTGATGAAGCAGAAGATGATTTTAAAAAAGTGGTTTGTGTTTGGGATGCAGAACTACGGGAACTTCGAGCTGAATGTTTTA TAAAAGAAGGAGAACCTAGGAAAGCTATAAGTGACTTAAAAGCTGCGTCAAAGTTGAAGAATGATAATACTGAAGCGTTTTATAAAATAA GCACACTGTACTACCAACTAGGAGACCACGAACTGTCCCTCAGTGAAGTTCGGGAATGTCTTAAACTTGACCAGGATCATAAAAGGTGTT TTGCACACTATAAACAAGTAAAGAAACTTAATAAGCTGATTGAGTCAGCTGAAGAGCTCATCAGAGATGGCAGATACACAGATGCTACCA GCAAATATGAATCTGTCATGAAAACAGAGCCAAGCATTGCTGAATATACAGTTCGTTCAAAGGAGAGGATTTGCCACTGCTTTTCTAAGG ACGAGAAGCCTGTTGAAGCTATTAGGGTTTGTTCTGAAGTTTTACAGATGGAACCTGACAATGTGAATGCCCTGAAAGATCGAGCAGAGG CCTATTTGATAGAGGAAATGTATGATGAAGGTTATATACAGGCATGTAGAGGACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTT CCATATTTGCGCTCTTTGGAATGAAGTGTACCAAAGTCGGAGGCTCCGATAAAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTAT TCATACTGTCAGGGCTGTGCTCAATGACTGGATGTTCCCTATATGCAAACAAAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGC AAAAGTATGAATTAGGAGCCGCTCTGTTTATTGGATGGGCAGGAGCCTCACTGTGCATAATTGGTGGTGTCATATTTTGCTTTTCAATAT CTGACAACAACAAAACACCCAGATACACATACAACGGGGCCACATCTGTCATGTCTTCTCGGACAAAGTATCATGGTGGAGAAGATTTTA AAACAACAAACCCTTCAAAACAGTTTGATAAAAATGCTTATGTCTAAAAGAGCTCGCTGGCAAGCTGCCTCTTGAGTTTGTTATAAAAGC GAACTGTTCACAAAATGATCCCATCAAGGCCCTCCCATAATTAACACTCAAAACTATTTTTAAAATATGCATTTGAAGCATCTGTTGATT GTATGGATGTAAGTGTTCTTACATAGTTAGTTATATACTAATCATTTTCTGTTGTGGCTTTCTATAAAAAATAAACAGTTTATTTACAGG >23537_23537_5_DNAJC3-CLDN10_DNAJC3_chr13_96416207_ENST00000376795_CLDN10_chr13_96212386_ENST00000299339_length(amino acids)=486AA_BP=25 MLPERRRVLVGHTPFLLFTREPSDMVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDG DPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVVCVWDAELRELRAECFIKEGEPRKA ISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKT EPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEGYIQACRGLMIAAVSLGFFGSIFALFGMK CTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRY -------------------------------------------------------------- >23537_23537_6_DNAJC3-CLDN10_DNAJC3_chr13_96416207_ENST00000376795_CLDN10_chr13_96212386_ENST00000376873_length(transcript)=3232nt_BP=1020nt CGAGAGCCGACGGCGGGCGGGCGCAGCTGCTGCCGGAGCGCCGGCGCGTGCTGGTGGGCCACACACCTTTCCTCCTCTTCACTCGCGAGC CCTCGGACATGGTGGCCCCCGGCTCCGTGACCAGCCGGCTGGGCTCGGTATTCCCCTTCCTGCTAGTCCTGGTGGATCTGCAGTACGAAG GTGCTGAATGTGGAGTAAATGCAGATGTTGAGAAACATCTTGAATTGGGCAAGAAATTACTTGCAGCTGGACAGCTAGCTGATGCTTTAT CTCAGTTTCATGCTGCCGTAGATGGTGACCCTGATAACTATATTGCTTATTATCGGAGGGCTACTGTCTTTTTAGCTATGGGCAAATCAA AAGCTGCACTTCCTGATTTAACTAAAGTGATTCAATTGAAGATGGACTTCACTGCAGCAAGATTACAGAGAGGTCACTTATTACTCAAAC AAGGAAAACTTGATGAAGCAGAAGATGATTTTAAAAAAGTGGTTTGTGTTTGGGATGCAGAACTACGGGAACTTCGAGCTGAATGTTTTA TAAAAGAAGGAGAACCTAGGAAAGCTATAAGTGACTTAAAAGCTGCGTCAAAGTTGAAGAATGATAATACTGAAGCGTTTTATAAAATAA GCACACTGTACTACCAACTAGGAGACCACGAACTGTCCCTCAGTGAAGTTCGGGAATGTCTTAAACTTGACCAGGATCATAAAAGGTGTT TTGCACACTATAAACAAGTAAAGAAACTTAATAAGCTGATTGAGTCAGCTGAAGAGCTCATCAGAGATGGCAGATACACAGATGCTACCA GCAAATATGAATCTGTCATGAAAACAGAGCCAAGCATTGCTGAATATACAGTTCGTTCAAAGGAGAGGATTTGCCACTGCTTTTCTAAGG ACGAGAAGCCTGTTGAAGCTATTAGGGTTTGTTCTGAAGTTTTACAGATGGAACCTGACAATGTGAATGCCCTGAAAGATCGAGCAGAGG CCTATTTGATAGAGGAAATGTATGATGAAGGTTATATACAGGCATGTAGAGGACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTT CCATATTTGCGCTCTTTGGAATGAAGTGTACCAAAGTCGGAGGCTCCGATAAAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTAT TCATACTGTCAGGGCTGTGCTCAATGACTGGATGTTCCCTATATGCAAACAAAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGC AAAAGTATGAATTAGGAGCCGCTCTGTTTATTGGATGGGCAGGAGCCTCACTGTGCATAATTGGTGGTGTCATATTTTGCTTTTCAATAT CTGACAACAACAAAACACCCAGATACACATACAACGGGGCCACATCTGTCATGTCTTCTCGGACAAAGTATCATGGTGGAGAAGATTTTA AAACAACAAACCCTTCAAAACAGTTTGATAAAAATGCTTATGTCTAAAAGAGCTCGCTGGCAAGCTGCCTCTTGAGTTTGTTATAAAAGC GAACTGTTCACAAAATGATCCCATCAAGGCCCTCCCATAATTAACACTCAAAACTATTTTTAAAATATGCATTTGAAGCATCTGTTGATT GTATGGATGTAAGTGTTCTTACATAGTTAGTTATATACTAATCATTTTCTGTTGTGGCTTTCTATAAAAAATAAACAGTTTATTTACAGG ATTTGTAAAATGTTTTCTACATTTATATAGAACATGAAAAGCATTTAGTACCAAAGGTTCAAGAAGTATTCGTACTCTAGCCTTTTTAAT CATTCATAGATAGAAGTCTTTGTACCCACTCCTTATGTTTCTTTTCATTCATAAACAGGTGTATAAGGAACAATGTCTTATAAACAGCAT GGGGGCAATCTGAGAATATTCCTCAAAAGGTGTCCAGGTTAAATAGACATGTTACTGGCTGCACACAGGCAAATTCTAGTTTGTTTTTTT TAAGTATTCTACAACATTTATTTAAAAAGGTAAATCTTTTTGTTGAAGCAGCAAGTTATCTGGTAGAACTTAACTTCTACAGGATCAGAG AGGATCTTGCTCATTCATGGCCATATCCACATGCCCATGGCCACTCAGTAGATTGTTGAAAAAGCAAAGCCACACCATTCTCTTTGATGT ATGCAGAGAGTTACGTAGCAGGGGATGTTCTCTGATTTATTCCACTGGCACCATTAGTGAATATTTAGTTGTTTTCATAAACGATGCTGT GATGAAGACTCATGTACATATTTAGCAAATTTTGGTTTCTTACATGTGCCTGTCATGACTGTAATTCATTATGACTGCTCCAGGAAGGGC TAATGGGGCCAATATATTATTGCCTGTCATGTGGCACATCCATGTTAAGGGGCTGAGGCGTCCCTGGCACGGAATGCAGAGCCCTGAGCT AGGGCATCAGCAGAAGCTGAGATAGAGATATTGGTCATGGTTGACTGAGGAGCCAATTAAAACCTGTTTATGCCTAGTGTTCCATTATTG GAACACTAAGCATGTGGGAGTTATTTATATCCTACTGCTCAAGGTCATCGCCAAGGTGTGATTGGAAAAATTCAAAAAATTGCAACCTCA GGCATAAATGGGTTAAGGACATCCCAAGCCCAAGTGGTACGTGCCTCACTCAGAACTGACGGGCCGAGTTCTATCTAGGTGTGTCTTCCA GAACCTGTTTACGGCTAACTGGATAACTGAGAGACTTGTCATTTCTAAAGACATTTAAGTTGCTCCAGGGATTTCTGAAAAAAGACACAG GCTTCTTCCTAGAGCCAGCCCTATATAACATGCCCACAAGGGCAACAGTTATCACAGTTCATACACACCTTTCATGTCCTGTCTCACTCA CTCCTCACAGCCATCCTAGGAGATACATATTGTTTTCATCCTGCATTTACAGAAAAAGAAATGAAAACAGAGAGCTTAAATAATTTGCCA CAGTAATGTCGAAACTAGGCCTTTGAACCAAGGCAGTCTAGGGTAAAATATAGTTTCAAAGTATGAATAAGAATTGGTATTTGTGTTATC TTTGAGTAAGAAACTGTCCGATATGAATCACAACGTGGGTGAATGTAGTATTTTCCTGAAGTGTGAAAGACTTAAAAAAAAGAATCACAT >23537_23537_6_DNAJC3-CLDN10_DNAJC3_chr13_96416207_ENST00000376795_CLDN10_chr13_96212386_ENST00000376873_length(amino acids)=486AA_BP=25 MLPERRRVLVGHTPFLLFTREPSDMVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDG DPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVVCVWDAELRELRAECFIKEGEPRKA ISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKT EPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEGYIQACRGLMIAAVSLGFFGSIFALFGMK CTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANKITTEFFDPLFVEQKYELGAALFIGWAGASLCIIGGVIFCFSISDNNKTPRY -------------------------------------------------------------- >23537_23537_7_DNAJC3-CLDN10_DNAJC3_chr13_96416207_ENST00000602402_CLDN10_chr13_96212386_ENST00000299339_length(transcript)=1892nt_BP=1192nt AGAGCCACTGAGGCCTGAGCGAGAGCCGACGGCGGGCGGGCGCAGCTGCTGCCGGAGCGCCGGCGCGTGCTGGTGGGCCACACACCTTTC CTCCTCTTCACTCGCGAGCCCTCGGACATGGTGGCCCCCGGCTCCGTGACCAGCCGGCTGGGCTCGGTATTCCCCTTCCTGCTAGTCCTG GTGGATCTGCAGTACGAAGGTGCTGAATGTGGAGTAAATGCAGATGTTGAGAAACATCTTGAATTGGGCAAGAAATTACTTGCAGCTGGA CAGCTAGCTGATGCTTTATCTCAGTTTCATGCTGCCGTAGATGGTGACCCTGATAACTATATTGCTTATTATCGGAGGGCTACTGTCTTT TTAGCTATGGGCAAATCAAAAGCTGCACTTCCTGATTTAACTAAAGTGATTCAATTGAAGATGGACTTCACTGCAGCAAGATTACAGAGA GGTCACTTATTACTCAAACAAGGAAAACTTGATGAAGCAGAAGATGATTTTAAAAAAGTGCTCAAATCTAATCCAAGTGAAAATGAAGAA AAGGAAGCACAGTCTCAACTTATAAAATCTGATGAAATGCAGCGTTTGCGTTCACAAGCACTTAACGCTTTTGGAAGTGGAGATTATACT GCTGCTATAGCCTTCCTTGATAAGATTTTAGAGGTTTGTGTTTGGGATGCAGAACTACGGGAACTTCGAGCTGAATGTTTTATAAAAGAA GGAGAACCTAGGAAAGCTATAAGTGACTTAAAAGCTGCGTCAAAGTTGAAGAATGATAATACTGAAGCGTTTTATAAAATAAGCACACTG TACTACCAACTAGGAGACCACGAACTGTCCCTCAGTGAAGTTCGGGAATGTCTTAAACTTGACCAGGATCATAAAAGGTGTTTTGCACAC TATAAACAAGTAAAGAAACTTAATAAGCTGATTGAGTCAGCTGAAGAGCTCATCAGAGATGGCAGATACACAGATGCTACCAGCAAATAT GAATCTGTCATGAAAACAGAGCCAAGCATTGCTGAATATACAGTTCGTTCAAAGGAGAGGATTTGCCACTGCTTTTCTAAGGACGAGAAG CCTGTTGAAGCTATTAGGGTTTGTTCTGAAGTTTTACAGATGGAACCTGACAATGTGAATGCCCTGAAAGATCGAGCAGAGGCCTATTTG ATAGAGGAAATGTATGATGAAGGTTATATACAGGCATGTAGAGGACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTT GCGCTCTTTGGAATGAAGTGTACCAAAGTCGGAGGCTCCGATAAAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTG TCAGGGCTGTGCTCAATGACTGGATGTTCCCTATATGCAAACAAAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAGTAT GAATTAGGAGCCGCTCTGTTTATTGGATGGGCAGGAGCCTCACTGTGCATAATTGGTGGTGTCATATTTTGCTTTTCAATATCTGACAAC AACAAAACACCCAGATACACATACAACGGGGCCACATCTGTCATGTCTTCTCGGACAAAGTATCATGGTGGAGAAGATTTTAAAACAACA AACCCTTCAAAACAGTTTGATAAAAATGCTTATGTCTAAAAGAGCTCGCTGGCAAGCTGCCTCTTGAGTTTGTTATAAAAGCGAACTGTT CACAAAATGATCCCATCAAGGCCCTCCCATAATTAACACTCAAAACTATTTTTAAAATATGCATTTGAAGCATCTGTTGATTGTATGGAT GTAAGTGTTCTTACATAGTTAGTTATATACTAATCATTTTCTGTTGTGGCTTTCTATAAAAAATAAACAGTTTATTTACAGGATTTGTAA >23537_23537_7_DNAJC3-CLDN10_DNAJC3_chr13_96416207_ENST00000602402_CLDN10_chr13_96212386_ENST00000299339_length(amino acids)=537AA_BP=25 MLPERRRVLVGHTPFLLFTREPSDMVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDG DPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQR LRSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVR ECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQME PDNVNALKDRAEAYLIEEMYDEGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANK -------------------------------------------------------------- >23537_23537_8_DNAJC3-CLDN10_DNAJC3_chr13_96416207_ENST00000602402_CLDN10_chr13_96212386_ENST00000376873_length(transcript)=3404nt_BP=1192nt AGAGCCACTGAGGCCTGAGCGAGAGCCGACGGCGGGCGGGCGCAGCTGCTGCCGGAGCGCCGGCGCGTGCTGGTGGGCCACACACCTTTC CTCCTCTTCACTCGCGAGCCCTCGGACATGGTGGCCCCCGGCTCCGTGACCAGCCGGCTGGGCTCGGTATTCCCCTTCCTGCTAGTCCTG GTGGATCTGCAGTACGAAGGTGCTGAATGTGGAGTAAATGCAGATGTTGAGAAACATCTTGAATTGGGCAAGAAATTACTTGCAGCTGGA CAGCTAGCTGATGCTTTATCTCAGTTTCATGCTGCCGTAGATGGTGACCCTGATAACTATATTGCTTATTATCGGAGGGCTACTGTCTTT TTAGCTATGGGCAAATCAAAAGCTGCACTTCCTGATTTAACTAAAGTGATTCAATTGAAGATGGACTTCACTGCAGCAAGATTACAGAGA GGTCACTTATTACTCAAACAAGGAAAACTTGATGAAGCAGAAGATGATTTTAAAAAAGTGCTCAAATCTAATCCAAGTGAAAATGAAGAA AAGGAAGCACAGTCTCAACTTATAAAATCTGATGAAATGCAGCGTTTGCGTTCACAAGCACTTAACGCTTTTGGAAGTGGAGATTATACT GCTGCTATAGCCTTCCTTGATAAGATTTTAGAGGTTTGTGTTTGGGATGCAGAACTACGGGAACTTCGAGCTGAATGTTTTATAAAAGAA GGAGAACCTAGGAAAGCTATAAGTGACTTAAAAGCTGCGTCAAAGTTGAAGAATGATAATACTGAAGCGTTTTATAAAATAAGCACACTG TACTACCAACTAGGAGACCACGAACTGTCCCTCAGTGAAGTTCGGGAATGTCTTAAACTTGACCAGGATCATAAAAGGTGTTTTGCACAC TATAAACAAGTAAAGAAACTTAATAAGCTGATTGAGTCAGCTGAAGAGCTCATCAGAGATGGCAGATACACAGATGCTACCAGCAAATAT GAATCTGTCATGAAAACAGAGCCAAGCATTGCTGAATATACAGTTCGTTCAAAGGAGAGGATTTGCCACTGCTTTTCTAAGGACGAGAAG CCTGTTGAAGCTATTAGGGTTTGTTCTGAAGTTTTACAGATGGAACCTGACAATGTGAATGCCCTGAAAGATCGAGCAGAGGCCTATTTG ATAGAGGAAATGTATGATGAAGGTTATATACAGGCATGTAGAGGACTTATGATCGCTGCTGTCAGCCTGGGCTTCTTTGGTTCCATATTT GCGCTCTTTGGAATGAAGTGTACCAAAGTCGGAGGCTCCGATAAAGCCAAAGCTAAAATTGCTTGTTTGGCTGGGATTGTATTCATACTG TCAGGGCTGTGCTCAATGACTGGATGTTCCCTATATGCAAACAAAATCACAACGGAATTCTTTGATCCTCTCTTTGTTGAGCAAAAGTAT GAATTAGGAGCCGCTCTGTTTATTGGATGGGCAGGAGCCTCACTGTGCATAATTGGTGGTGTCATATTTTGCTTTTCAATATCTGACAAC AACAAAACACCCAGATACACATACAACGGGGCCACATCTGTCATGTCTTCTCGGACAAAGTATCATGGTGGAGAAGATTTTAAAACAACA AACCCTTCAAAACAGTTTGATAAAAATGCTTATGTCTAAAAGAGCTCGCTGGCAAGCTGCCTCTTGAGTTTGTTATAAAAGCGAACTGTT CACAAAATGATCCCATCAAGGCCCTCCCATAATTAACACTCAAAACTATTTTTAAAATATGCATTTGAAGCATCTGTTGATTGTATGGAT GTAAGTGTTCTTACATAGTTAGTTATATACTAATCATTTTCTGTTGTGGCTTTCTATAAAAAATAAACAGTTTATTTACAGGATTTGTAA AATGTTTTCTACATTTATATAGAACATGAAAAGCATTTAGTACCAAAGGTTCAAGAAGTATTCGTACTCTAGCCTTTTTAATCATTCATA GATAGAAGTCTTTGTACCCACTCCTTATGTTTCTTTTCATTCATAAACAGGTGTATAAGGAACAATGTCTTATAAACAGCATGGGGGCAA TCTGAGAATATTCCTCAAAAGGTGTCCAGGTTAAATAGACATGTTACTGGCTGCACACAGGCAAATTCTAGTTTGTTTTTTTTAAGTATT CTACAACATTTATTTAAAAAGGTAAATCTTTTTGTTGAAGCAGCAAGTTATCTGGTAGAACTTAACTTCTACAGGATCAGAGAGGATCTT GCTCATTCATGGCCATATCCACATGCCCATGGCCACTCAGTAGATTGTTGAAAAAGCAAAGCCACACCATTCTCTTTGATGTATGCAGAG AGTTACGTAGCAGGGGATGTTCTCTGATTTATTCCACTGGCACCATTAGTGAATATTTAGTTGTTTTCATAAACGATGCTGTGATGAAGA CTCATGTACATATTTAGCAAATTTTGGTTTCTTACATGTGCCTGTCATGACTGTAATTCATTATGACTGCTCCAGGAAGGGCTAATGGGG CCAATATATTATTGCCTGTCATGTGGCACATCCATGTTAAGGGGCTGAGGCGTCCCTGGCACGGAATGCAGAGCCCTGAGCTAGGGCATC AGCAGAAGCTGAGATAGAGATATTGGTCATGGTTGACTGAGGAGCCAATTAAAACCTGTTTATGCCTAGTGTTCCATTATTGGAACACTA AGCATGTGGGAGTTATTTATATCCTACTGCTCAAGGTCATCGCCAAGGTGTGATTGGAAAAATTCAAAAAATTGCAACCTCAGGCATAAA TGGGTTAAGGACATCCCAAGCCCAAGTGGTACGTGCCTCACTCAGAACTGACGGGCCGAGTTCTATCTAGGTGTGTCTTCCAGAACCTGT TTACGGCTAACTGGATAACTGAGAGACTTGTCATTTCTAAAGACATTTAAGTTGCTCCAGGGATTTCTGAAAAAAGACACAGGCTTCTTC CTAGAGCCAGCCCTATATAACATGCCCACAAGGGCAACAGTTATCACAGTTCATACACACCTTTCATGTCCTGTCTCACTCACTCCTCAC AGCCATCCTAGGAGATACATATTGTTTTCATCCTGCATTTACAGAAAAAGAAATGAAAACAGAGAGCTTAAATAATTTGCCACAGTAATG TCGAAACTAGGCCTTTGAACCAAGGCAGTCTAGGGTAAAATATAGTTTCAAAGTATGAATAAGAATTGGTATTTGTGTTATCTTTGAGTA AGAAACTGTCCGATATGAATCACAACGTGGGTGAATGTAGTATTTTCCTGAAGTGTGAAAGACTTAAAAAAAAGAATCACATTGTTCAGA >23537_23537_8_DNAJC3-CLDN10_DNAJC3_chr13_96416207_ENST00000602402_CLDN10_chr13_96212386_ENST00000376873_length(amino acids)=537AA_BP=25 MLPERRRVLVGHTPFLLFTREPSDMVAPGSVTSRLGSVFPFLLVLVDLQYEGAECGVNADVEKHLELGKKLLAAGQLADALSQFHAAVDG DPDNYIAYYRRATVFLAMGKSKAALPDLTKVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQR LRSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVR ECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQME PDNVNALKDRAEAYLIEEMYDEGYIQACRGLMIAAVSLGFFGSIFALFGMKCTKVGGSDKAKAKIACLAGIVFILSGLCSMTGCSLYANK -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for DNAJC3-CLDN10 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for DNAJC3-CLDN10 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for DNAJC3-CLDN10 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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