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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DNMBP-CWF19L1 (FusionGDB2 ID:23683)

Fusion Gene Summary for DNMBP-CWF19L1

check button Fusion gene summary
Fusion gene informationFusion gene name: DNMBP-CWF19L1
Fusion gene ID: 23683
HgeneTgene
Gene symbol

DNMBP

CWF19L1

Gene ID

23268

55280

Gene namedynamin binding proteinCWF19 like cell cycle control factor 1
SynonymsARHGEF36|CTRCT48|TUBAC19L1|SCAR17|hDrn1
Cytomap

10q24.2

10q24.31

Type of geneprotein-codingprotein-coding
Descriptiondynamin-binding proteinscaffold protein TUBACWF19-like protein 1CWF19 like 1, cell cycle controlCWF19-like 1 cell cycle controlhuman Dbr1 associated ribonuclease 1
Modification date2020031320200313
UniProtAcc

Q6XZF7

Q69YN2

Ensembl transtripts involved in fusion geneENST00000324109, ENST00000342239, 
ENST00000540316, ENST00000543621, 
ENST00000472036, 		ENST00000370379, 
ENST00000478047, ENST00000354105, 
Fusion gene scores* DoF score9 X 9 X 5=4054 X 4 X 4=64
# samples 104
** MAII scorelog2(10/405*10)=-2.01792190799726
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/64*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DNMBP [Title/Abstract] AND CWF19L1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDNMBP(101639568)-CWF19L1(102020076), # samples:1
Anticipated loss of major functional domain due to fusion event.DNMBP-CWF19L1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across DNMBP (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CWF19L1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-A4J9-01ADNMBPchr10

101639568

-CWF19L1chr10

102020076

-


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Fusion Gene ORF analysis for DNMBP-CWF19L1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000324109ENST00000370379DNMBPchr10

101639568

-CWF19L1chr10

102020076

-
5CDS-intronENST00000324109ENST00000478047DNMBPchr10

101639568

-CWF19L1chr10

102020076

-
5CDS-intronENST00000342239ENST00000370379DNMBPchr10

101639568

-CWF19L1chr10

102020076

-
5CDS-intronENST00000342239ENST00000478047DNMBPchr10

101639568

-CWF19L1chr10

102020076

-
5CDS-intronENST00000540316ENST00000370379DNMBPchr10

101639568

-CWF19L1chr10

102020076

-
5CDS-intronENST00000540316ENST00000478047DNMBPchr10

101639568

-CWF19L1chr10

102020076

-
5CDS-intronENST00000543621ENST00000370379DNMBPchr10

101639568

-CWF19L1chr10

102020076

-
5CDS-intronENST00000543621ENST00000478047DNMBPchr10

101639568

-CWF19L1chr10

102020076

-
Frame-shiftENST00000540316ENST00000354105DNMBPchr10

101639568

-CWF19L1chr10

102020076

-
Frame-shiftENST00000543621ENST00000354105DNMBPchr10

101639568

-CWF19L1chr10

102020076

-
In-frameENST00000324109ENST00000354105DNMBPchr10

101639568

-CWF19L1chr10

102020076

-
In-frameENST00000342239ENST00000354105DNMBPchr10

101639568

-CWF19L1chr10

102020076

-
intron-3CDSENST00000472036ENST00000354105DNMBPchr10

101639568

-CWF19L1chr10

102020076

-
intron-intronENST00000472036ENST00000370379DNMBPchr10

101639568

-CWF19L1chr10

102020076

-
intron-intronENST00000472036ENST00000478047DNMBPchr10

101639568

-CWF19L1chr10

102020076

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000342239DNMBPchr10101639568-ENST00000354105CWF19L1chr10102020076-707147129247591555
ENST00000324109DNMBPchr10101639568-ENST00000354105CWF19L1chr10102020076-699946409246871531

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000342239ENST00000354105DNMBPchr10101639568-CWF19L1chr10102020076-0.0008842030.99911577
ENST00000324109ENST00000354105DNMBPchr10101639568-CWF19L1chr10102020076-0.000771180.99922884

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Fusion Genomic Features for DNMBP-CWF19L1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for DNMBP-CWF19L1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:101639568/chr10:102020076)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DNMBP

Q6XZF7

CWF19L1

Q69YN2

FUNCTION: Plays a critical role as a guanine nucleotide exchange factor (GEF) for CDC42 in several intracellular processes associated with the actin and microtubule cytoskeleton. Regulates the structure of apical junctions through F-actin organization in epithelial cells (PubMed:19767742, PubMed:17015620). Participates in the normal lumenogenesis of epithelial cell cysts by regulating spindle orientation (PubMed:20479467). Plays a role in ciliogenesis (By similarity). May play a role in membrane trafficking between the cell surface and the Golgi (By similarity). {ECO:0000250|UniProtKB:E2RP94, ECO:0000250|UniProtKB:Q6TXD4, ECO:0000269|PubMed:17015620, ECO:0000269|PubMed:19767742, ECO:0000269|PubMed:20479467}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDNMBPchr10:101639568chr10:102020076ENST00000324109-16171136_117315161578.0Coiled coilOntology_term=ECO:0000255
HgeneDNMBPchr10:101639568chr10:102020076ENST00000324109-1617693_75715161578.0Coiled coilOntology_term=ECO:0000255
HgeneDNMBPchr10:101639568chr10:102020076ENST00000543621-1314693_757762824.0Coiled coilOntology_term=ECO:0000255
HgeneDNMBPchr10:101639568chr10:102020076ENST00000324109-16171351_144915161578.0Compositional biasNote=Ser-rich
HgeneDNMBPchr10:101639568chr10:102020076ENST00000324109-1617610_64915161578.0Compositional biasNote=Pro-rich
HgeneDNMBPchr10:101639568chr10:102020076ENST00000543621-1314610_649762824.0Compositional biasNote=Pro-rich
HgeneDNMBPchr10:101639568chr10:102020076ENST00000324109-16171008_121715161578.0DomainBAR
HgeneDNMBPchr10:101639568chr10:102020076ENST00000324109-16171285_134815161578.0DomainSH3 5
HgeneDNMBPchr10:101639568chr10:102020076ENST00000324109-1617145_20415161578.0DomainSH3 3
HgeneDNMBPchr10:101639568chr10:102020076ENST00000324109-1617243_30215161578.0DomainSH3 4
HgeneDNMBPchr10:101639568chr10:102020076ENST00000324109-16172_6115161578.0DomainSH3 1
HgeneDNMBPchr10:101639568chr10:102020076ENST00000324109-161766_12615161578.0DomainSH3 2
HgeneDNMBPchr10:101639568chr10:102020076ENST00000324109-1617784_96715161578.0DomainDH
HgeneDNMBPchr10:101639568chr10:102020076ENST00000543621-1314145_204762824.0DomainSH3 3
HgeneDNMBPchr10:101639568chr10:102020076ENST00000543621-1314243_302762824.0DomainSH3 4
HgeneDNMBPchr10:101639568chr10:102020076ENST00000543621-13142_61762824.0DomainSH3 1
HgeneDNMBPchr10:101639568chr10:102020076ENST00000543621-131466_126762824.0DomainSH3 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDNMBPchr10:101639568chr10:102020076ENST00000543621-13141136_1173762824.0Coiled coilOntology_term=ECO:0000255
HgeneDNMBPchr10:101639568chr10:102020076ENST00000543621-13141351_1449762824.0Compositional biasNote=Ser-rich
HgeneDNMBPchr10:101639568chr10:102020076ENST00000324109-16171513_157615161578.0DomainSH3 6
HgeneDNMBPchr10:101639568chr10:102020076ENST00000543621-13141008_1217762824.0DomainBAR
HgeneDNMBPchr10:101639568chr10:102020076ENST00000543621-13141285_1348762824.0DomainSH3 5
HgeneDNMBPchr10:101639568chr10:102020076ENST00000543621-13141513_1576762824.0DomainSH3 6
HgeneDNMBPchr10:101639568chr10:102020076ENST00000543621-1314784_967762824.0DomainDH


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Fusion Gene Sequence for DNMBP-CWF19L1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>23683_23683_1_DNMBP-CWF19L1_DNMBP_chr10_101639568_ENST00000324109_CWF19L1_chr10_102020076_ENST00000354105_length(transcript)=6999nt_BP=4640nt
AGGGGCGGAGGTGACAGCGGGCTGGGGACTGGCGGCTGCAACTGCCTGCCGCGCCGAGGGACCGCCGGGCGGCGGAAAGCAGGTTATAAA
ACATGGAGGCTGGCTCAGTGGTTCGAGCCATTTTTGACTTCTGCCCTAGCGTATCAGAAGAACTGCCGCTCTTTGTGGGAGATATTATTG
AGGTGCTGGCAGTGGTGGATGAATTTTGGCTTCTAGGAAAGAAGGAGGATGTTACAGGACAATTCCCCAGCAGTTTTGTGGAAATTGTGA
CCATTCCCAGTCTAAAAGAGGGAGAGAGGCTGTTTGTGTGCATTTGTGAATTCACATCCCAAGAGTTGGATAATCTTCCCCTCCATCGAG
GTGACCTGGTGATTCTCGATGGCATTCCCACTGCAGGCTGGCTGCAGGGCCGAAGCTGCTGGGGCGCACGGGGCTTCTTCCCATCTTCAT
GTGTCCGCGAGCTCTGCCTCTCCTCACAGAGCCGGCAGTGGCACTCCCAGAGCGCCCTGTTTCAGATTCCGGAATATTCCATGGGACAAG
CCCGGGCCCTAATGGGGCTTTCTGCTCAGCTGGATGAAGAGCTGGACTTCAGGGAAGGGGATGTGATCACCATTATTGGAGTTCCTGAAC
CAGGCTGGTTTGAAGGGGAGTTAGAGGGCCGAAGAGGCATTTTTCCAGAAGGTTTTGTAGAGCTGTTGGGGCCCCTGAGGACTGTGGATG
AGTCAGTAAGTTCTGGAAATCAAGATGACTGCATTGTTAATGGTGAAGTAGATACCCCTGTAGGAGAAGAAGAGATAGGGCCGGATGAGG
ATGAGGAGGAGCCAGGGACCTATGGGGTCGCCCTGTACAGATTCCAAGCCCTGGAGCCAAATGAGCTGGATTTCGAGGTCGGGGATAAAA
TCCGAATTCTGGCGACCTTGGAAGATGGCTGGCTGGAAGGATCCCTGAAGGGCAGGACAGGCATCTTTCCTTACCGGTTTGTGAAATTAT
GTCCTGACACACGGGTGGAGGAAACCATGGCTCTGCCCCAGGAAGGCAGCCTTGCCAGGATCCCGGAAACTTCTTTGGATTGTTTGGAGA
ACACCTTAGGAGTAGAGGAACAAAGACATGAAACCAGTGACCATGAGGCCGAGGAGCCTGACTGCATTATTTCTGAAGCACCCACTTCTC
CCCTCGGTCATCTGACTTCAGAGTATGACACAGACAGAAACTCTTATCAGGACGAGGACACCGCAGGAGGGCCCCCGAGAAGCCCAGGCG
TGGAGTGGGAAATGCCTCTTGCCACAGACTCTCCCACATCTGACCCTACAGAAGTAGTCAATGGTATTTCCTCCCAACCTCAGGTCCCTT
TTCATCCCAACTTGCAGAAAAGCCAGTATTATTCTACAGTGGGAGGGAGCCACCCGCACTCAGAACAGTACCCCGACCTTCTTCCCCTAG
AAGCAAGGACTAGAGACTATGCCAGCCTACCTCCCAAAAGAATGTATTCCCAGCTAAAAACTCTTCAGAAGCCAGTGCTCCCTCTTTACA
GGGGCTCTTCTGTTTCAGCTTCAAGGGTAGTCAAACCCAGACAATCAAGTCCTCAGCTCCACAACCTAGCAAGTTATACTAAAAAGCACC
ACACGTCCAGTGTTTACTCCATCTCAGAGAGATTGGAGATGAAGCCTGGTCCGCAAGCCCAAGGGCTTGTTATGGAAGCAGCAACACATT
CACAGGGAGACGGCAGCACTGACCTGGACTCGAAGCTGACACAACAGCTGATCGAGTTTGAGAAGAGCTTGGCAGGGCCCGGCACAGAGC
CAGATAAAATTTTACGCCACTTTTCAATCATGGACTTTAACTCTGAGAAGGATATTGTCCGAGGTTCCTCAAAGTTAATCACCGAGCAGG
AGCTGCCGGAAAGGAGAAAGGCCCTAAGGCCACCGCCACCTCGTCCCTGTACTCCGGTATCCACTTCTCCCCATTTGCTGGTTGACCAGA
ACCTAAAACCTGCACCACCCTTGGTGGTGCGACCCTCTCGCCCAGCTCCCCTGCCTCCCTCAGCACAGCAGAGAACGAATGCGGTATCCC
CCAAGCTCCTATCTCGACACCGTCCTACCTGTGAGACCTTAGAAAAGGAGGGCCCTGGTCATATGGGAAGGAGTCTGGACCAGACCTCCC
CATGCCCCTTAGTGCTGGTGAGGATTGAGGAAATGGAGCGGGACTTGGATATGTACAGTAGAGCTCAAGAAGAGCTAAACCTCATGCTGG
AGGAGAAGCAGGATGAATCATCAAGAGCAGAGACCCTCGAGGATCTCAAGTTCTGTGAAAGTAACATTGAAAGTTTGAATATGGAACTCC
AGCAACTAAGAGAAATGACGCTCCTCTCCTCCCAGTCTTCATCACTGGTGGCCCCTTCTGGGTCTGTGTCTGCCGAAAATCCAGAGCAGA
GGATGCTGGAGAAGAGAGCCAAGGTCATAGAAGAACTTCTTCAGACAGAAAGAGACTACATTCGGGATCTGGAAATGTGTATTGAGCGGA
TCATGGTACCCATGCAGCAGGCACAGGTACCAAACATTGATTTTGAGGGACTTTTTGGAAATATGCAGATGGTGATTAAGGTCTCGAAGC
AATTATTGGCTGCTCTGGAAATCAGCGATGCTGTAGGACCTGTGTTTCTTGGTCACCGGGATGAGCTTGAGGGAACATACAAGATTTACT
GCCAGAATCATGATGAGGCCATTGCGCTGCTTGAAATCTACGAGAAGGATGAGAAGATCCAGAAGCATCTTCAGGACTCCTTGGCAGATC
TGAAGAGCCTATACAACGAATGGGGATGCACAAATTATATTAACCTGGGCTCCTTCCTCATCAAACCAGTACAGAGAGTAATGCGTTACC
CGCTGTTGCTAATGGAGTTGCTGAATTCCACCCCAGAATCCCACCCAGATAAAGTGCCTTTAACCAATGCAGTCCTTGCGGTCAAGGAAA
TCAACGTTAACATTAATGAATATAAACGGCGAAAGGACCTGGTCCTCAAGTACCGTAAGGGTGATGAAGATAGCCTTATGGAGAAAATTT
CCAAACTGAACATCCACTCCATCATCAAGAAATCCAACCGAGTTAGCAGTCACCTGAAGCATCTCACTGGCTTTGCTCCTCAGATAAAAG
ATGAAGTATTTGAAGAAACAGAAAAAAACTTCCGAATGCAAGAAAGATTGATTAAGTCTTTTATCCGAGACCTGTCTCTCTACCTCCAGC
ACATCCGGGAGTCCGCATGTGTGAAAGTGGTGGCTGCTGTGAGCATGTGGGATGTGTGCATGGAGAGAGGACACCGGGACCTGGAGCAGT
TTGAGAGGGTGCATCGCTACATCAGTGACCAGCTCTTCACAAACTTTAAGGAGAGGACAGAGCGGCTTGTCATCTCCCCCTTAAATCAGT
TACTGAGCATGTTTACAGGGCCCCATAAGCTGGTACAGAAACGCTTTGACAAGCTCCTGGACTTCTATAACTGTACAGAACGGGCAGAAA
AGCTAAAGGACAAGAAGACCCTGGAGGAGCTGCAGTCGGCCCGGAACAACTATGAGGCCCTGAATGCACAGCTGCTGGATGAGCTGCCCA
AGTTCCACCAGTACGCCCAGGGCCTCTTCACCAACTGTGTCCACGGCTATGCTGAAGCCCACTGTGACTTTGTGCACCAGGCTCTGGAGC
AATTAAAGCCACTGCTTTCGTTACTCAAAGTGGCTGGCAGAGAGGGAAACCTTATTGCCATCTTCCACGAAGAGCACAGCAGAGTTCTGC
AGCAACTCCAGGTTTTTACCTTCTTCCCGGAGTCTCTTCCAGCTACCAAGAAGCCATTTGAGAGGAAAACCATTGACCGCCAGTCTGCTC
GAAAGCCACTCCTGGGCCTGCCAAGTTACATGCTACAGTCAGAAGAACTCCGGGCCTCCCTCCTGGCCAGGTATCCCCCTGAAAAACTCT
TCCAGGCAGAACGGAACTTCAATGCTGCTCAAGACTTGGATGTCTCACTTTTGGAAGGTGACCTGGTGGGTGTGATTAAGAAAAAAGACC
CCATGGGCAGCCAGAACCGCTGGCTGATTGACAATGGAGTCACCAAAGGCTTCGTGTACAGCTCTTTCCTAAAGCCCTACAATCCTCGCC
GCAGCCACTCCGATGCCTCCGTGGGTAGCCACTCCTCCACAGAGTCTGAGCACGGCAGCTCCTCCCCCAGGTTCCCACGCCAGAACAGCG
GCAGCACCCTGACCTTCAACCCCAGCAGCATGGCTGTATCCTTTACCTCGGGGTCTTGCCAGAAGCAGCCTCAAGATGCATCTCCTCCGC
CAAAAGAATGTGACCAAGGAACTCTCAGTGCATCCCTAAATCCGAGTAATTCAGAGAGTAGTCCTTCCAGATGCCCTTCAGACCCAGACT
CCACCTCCCAGCCAAGGTCAGGGGACTCTGCAGATGTAGCTAGAGATGTAAAGCAACCCACTGCCACGCCGAGGAGCTACCGGAACTTCA
GGCATCCAGAAATAGTTGGCTACTCCGTACCAGGACGAAATGGGCAAAGTCAAGACCTCGTCAAAGGATGTGCAAGAACAGCCCAGGCTC
CGGAAGACAGAAGTACAGAGCCAGATGGCAGTGAGGCAGAAGGCAACCAGCTCCTATTCAGACATATGTGCTTGGTGCTAATAACCAGGA
AACAGTAAAATATTTCCAGGATGCTGATGGATGTGAATTAGCTGAAAACATTACTTATCTGGGTCGTAAAGGTATCTTCACTGGAAGCTC
GGGGCTGCAGATTGTGTACCTCAGTGGGACAGAATCCTTAAATGAGCCAGTACCAGGTTATAGTTTTAGTCCCAAGGATGTGTCTTCTCT
GAGAATGATGCTGTGTACAACCTCCCAGTTTAAGGGTGTTGATATCTTGCTCACATCCCCATGGCCCAAGTGTGTGGGGAACTTTGGGAA
TTCTTCTGGAGAAGTGGATACCAAAAAATGTGGTTCTGCTTTGGTTTCCAGTCTTGCCACGGGCTTGAAACCAAGATACCATTTTGCTGC
TTTGGAAAAGACCTATTATGAGAGGCTTCCATATCGAAACCATATCATTCTACAGGAAAATGCACAGCATGCCACCCGGTTTATAGCTCT
GGCAAATGTTGGAAATCCAGAAAAGAAAAAGTATCTTTACGCGTTCAGTATTGTTCCCATGAAGCTAATGGATGCAGCAGAACTGGTAAA
ACAGCCTCCGGATGTCACTGAAAACCCTTACAGAAAATCTGGGCAGGAAGCATCCATAGGAAAGCAAATTCTTGCCCCTGTGGAAGAATC
AGCCTGTCAGTTTTTCTTTGATTTAAATGAAAAGCAGGGAAGGAAGCGTTCATCCACAGGTAGAGATAGCAAATCTTCTCCTCATCCAAA
GCAGCCTCGCAAACCTCCTCAGCCTCCAGGACCCTGCTGGTTTTGCCTTGCTAGCCCTGAAGTGGAAAAACATTTGGTGGTCAACATCGG
CACACATTGCTACCTTGCCCTGGCCAAAGGAGGCTTATCTGATGACCATGTCCTCATCCTGCCTATTGGACACTACCAGTCAGTGGTGGA
GCTTTCAGCAGAGGTGGTAGAAGAGGTGGAGAAGTATAAGGCCACTCTGAGACGGTTCTTTAAGAGTCGAGGGAAATGGTGTGTTGTATT
TGAGAGAAATTATAAGAGCCATCACCTCCAGCTACAGGTCATTCCTGTCCCAATCAGCTGCTCTACTACTGATGACATTAAAGATGCCTT
CATTACCCAGGCACAGGAGCAGCAGATAGAGCTGTTGGAAATCCCAGAGCACTCTGACATCAAGCAGATTGCACAGCCAGGAGCAGCATA
TTTTTATGTTGAACTTGACACAGGAGAAAAGCTTTTCCACAGAATTAAAAAGAATTTTCCTTTGCAGTTTGGAAGGGAGGTCCTGGCCAG
TGAAGCCATCCTTAATGTTCCTGATAAGTCTGACTGGAGGCAGTGTCAGATCAGCAAGGAAGACGAGGAGACCCTGGCTCGCCGCTTCCG
GAAAGACTTTGAGCCCTATGACTTTACTCTGGATGACTAAAACAAAGGGAAGAACTTTTTATGAACTCCACAGGAAGTAGTAAAGCTTTT
TTTTTTTTTTAATTAAAAGAATTTTTTTTGAGACAAAGTCTCGCTCTGTCACCCAAGCAGGATTGCAGTGGCATAACTGTGGCTCACTGT
AGCCTCAACCTCCTGGGCTCTAGAGTTCCTCCCACCTCAGCCTCATGAGTAGCTGGGACCACAGGCGCATGCTACCATGCCTGGCAAACT
TTTTTGATTTTTTATAGAGACAGGAGGGTCTCCCTGTGTTGCCCAGGCTGGTCTGTAATGCCTAGGCTCAAGGGATCCTCTGCCTTGGCT
TCTTAACCTGCTGGGATTACAAGCATGAGACACCATTCCTGGCCTAGAAGCCTATTTTTAAAGAAACTACAATCTCCCATGGGGACTGTT
TCCCTGCCTCTTTTGTGCAGTCCCATGGAACTTGCCTACAGCAAGAGGCCTAAGATTGAATCTTTTTGGGGAAAAGTCATTCTAGGATGA
AAATCCTATGTTAAGGCCGGGCGCAGTGGCTCACGCCTGTAATCCCAGTACTTTGGGAAGCCGAGGCAGGTGGATCACCTGAGGTGAGGA
GTTTGAGACCAGCCTGGCCAACATGGTGAAACCCCGTCTTTACTAAAGCTACAAAAATTAGCTGGGCGTGGTGCCAGGCACTTGTAATCC
CAGCTACTCAGGAGGCTGAGGCAGGAGAATTGCTTGAGCCTGGGAGGTGGAGGTTGCAGTGAGCCAAGATCGCTCCATTGCACTCCAGCC
TGGGTGACAGTGAAACTCCATCTCAAAAATAAAAGAATAAAAGTATGTCTGTCATCCAGCTCCTATGTCTGTTATCCAGCTCCAAGTACA

>23683_23683_1_DNMBP-CWF19L1_DNMBP_chr10_101639568_ENST00000324109_CWF19L1_chr10_102020076_ENST00000354105_length(amino acids)=1531AA_BP=1516
MEAGSVVRAIFDFCPSVSEELPLFVGDIIEVLAVVDEFWLLGKKEDVTGQFPSSFVEIVTIPSLKEGERLFVCICEFTSQELDNLPLHRG
DLVILDGIPTAGWLQGRSCWGARGFFPSSCVRELCLSSQSRQWHSQSALFQIPEYSMGQARALMGLSAQLDEELDFREGDVITIIGVPEP
GWFEGELEGRRGIFPEGFVELLGPLRTVDESVSSGNQDDCIVNGEVDTPVGEEEIGPDEDEEEPGTYGVALYRFQALEPNELDFEVGDKI
RILATLEDGWLEGSLKGRTGIFPYRFVKLCPDTRVEETMALPQEGSLARIPETSLDCLENTLGVEEQRHETSDHEAEEPDCIISEAPTSP
LGHLTSEYDTDRNSYQDEDTAGGPPRSPGVEWEMPLATDSPTSDPTEVVNGISSQPQVPFHPNLQKSQYYSTVGGSHPHSEQYPDLLPLE
ARTRDYASLPPKRMYSQLKTLQKPVLPLYRGSSVSASRVVKPRQSSPQLHNLASYTKKHHTSSVYSISERLEMKPGPQAQGLVMEAATHS
QGDGSTDLDSKLTQQLIEFEKSLAGPGTEPDKILRHFSIMDFNSEKDIVRGSSKLITEQELPERRKALRPPPPRPCTPVSTSPHLLVDQN
LKPAPPLVVRPSRPAPLPPSAQQRTNAVSPKLLSRHRPTCETLEKEGPGHMGRSLDQTSPCPLVLVRIEEMERDLDMYSRAQEELNLMLE
EKQDESSRAETLEDLKFCESNIESLNMELQQLREMTLLSSQSSSLVAPSGSVSAENPEQRMLEKRAKVIEELLQTERDYIRDLEMCIERI
MVPMQQAQVPNIDFEGLFGNMQMVIKVSKQLLAALEISDAVGPVFLGHRDELEGTYKIYCQNHDEAIALLEIYEKDEKIQKHLQDSLADL
KSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELLNSTPESHPDKVPLTNAVLAVKEINVNINEYKRRKDLVLKYRKGDEDSLMEKIS
KLNIHSIIKKSNRVSSHLKHLTGFAPQIKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHIRESACVKVVAAVSMWDVCMERGHRDLEQF
ERVHRYISDQLFTNFKERTERLVISPLNQLLSMFTGPHKLVQKRFDKLLDFYNCTERAEKLKDKKTLEELQSARNNYEALNAQLLDELPK
FHQYAQGLFTNCVHGYAEAHCDFVHQALEQLKPLLSLLKVAGREGNLIAIFHEEHSRVLQQLQVFTFFPESLPATKKPFERKTIDRQSAR
KPLLGLPSYMLQSEELRASLLARYPPEKLFQAERNFNAAQDLDVSLLEGDLVGVIKKKDPMGSQNRWLIDNGVTKGFVYSSFLKPYNPRR
SHSDASVGSHSSTESEHGSSSPRFPRQNSGSTLTFNPSSMAVSFTSGSCQKQPQDASPPPKECDQGTLSASLNPSNSESSPSRCPSDPDS
TSQPRSGDSADVARDVKQPTATPRSYRNFRHPEIVGYSVPGRNGQSQDLVKGCARTAQAPEDRSTEPDGSEAEGNQLLFRHMCLVLITRK

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>23683_23683_2_DNMBP-CWF19L1_DNMBP_chr10_101639568_ENST00000342239_CWF19L1_chr10_102020076_ENST00000354105_length(transcript)=7071nt_BP=4712nt
AGGGGCGGAGGTGACAGCGGGCTGGGGACTGGCGGCTGCAACTGCCTGCCGCGCCGAGGGACCGCCGGGCGGCGGAAAGCAGGTTATAAA
ACATGGAGGCTGGCTCAGTGGTTCGAGCCATTTTTGACTTCTGCCCTAGCGTATCAGAAGAACTGCCGCTCTTTGTGGGAGATATTATTG
AGGTGCTGGCAGTGGTGGATGAATTTTGGCTTCTAGGAAAGAAGGAGGATGTTACAGGACAATTCCCCAGCAGTTTTGTGGAAATTGTGA
CCATTCCCAGTCTAAAAGAGGGAGAGAGGCTGTTTGTGTGCATTTGTGAATTCACATCCCAAGAGTTGGATAATCTTCCCCTCCATCGAG
GTGACCTGGTGATTCTCGATGGCATTCCCACTGCAGGCTGGCTGCAGGGCCGAAGCTGCTGGGGCGCACGGGGCTTCTTCCCATCTTCAT
GTGTCCGCGAGCTCTGCCTCTCCTCACAGAGCCGGCAGTGGCACTCCCAGAGCGCCCTGTTTCAGATTCCGGAATATTCCATGGGACAAG
CCCGGGCCCTAATGGGGCTTTCTGCTCAGCTGGATGAAGAGCTGGACTTCAGGGAAGGGGATGTGATCACCATTATTGGAGTTCCTGAAC
CAGGCTGGTTTGAAGGGGAGTTAGAGGGCCGAAGAGGCATTTTTCCAGAAGGTTTTGTAGAGCTGTTGGGGCCCCTGAGGACTGTGGATG
AGTCAGTAAGTTCTGGAAATCAAGATGACTGCATTGTTAATGGTGAAGTAGATACCCCTGTAGGAGAAGAAGAGATAGGGCCGGATGAGG
ATGAGGAGGAGCCAGGGACCTATGGGGTCGCCCTGTACAGATTCCAAGCCCTGGAGCCAAATGAGCTGGATTTCGAGGTCGGGGATAAAA
TCCGAATTCTGGCGACCTTGGAAGATGGCTGGCTGGAAGGATCCCTGAAGGGCAGGACAGGCATCTTTCCTTACCGGTTTGTGAAATTAT
GTCCTGACACACGGGTGGAGGAAACCATGGCTCTGCCCCAGGAAGGCAGCCTTGCCAGGATCCCGGAAACTTCTTTGGATTGTTTGGAGA
ACACCTTAGGAGTAGAGGAACAAAGACATGAAACCAGTGACCATGAGGCCGAGGAGCCTGACTGCATTATTTCTGAAGCACCCACTTCTC
CCCTCGGTCATCTGACTTCAGAGTATGACACAGACAGAAACTCTTATCAGGACGAGGACACCGCAGGAGGGCCCCCGAGAAGCCCAGGCG
TGGAGTGGGAAATGCCTCTTGCCACAGACTCTCCCACATCTGACCCTACAGAAGTAGTCAATGGTATTTCCTCCCAACCTCAGGTCCCTT
TTCATCCCAACTTGCAGAAAAGCCAGTATTATTCTACAGTGGGAGGGAGCCACCCGCACTCAGAACAGTACCCCGACCTTCTTCCCCTAG
AAGCAAGGACTAGAGACTATGCCAGCCTACCTCCCAAAAGAATGTATTCCCAGCTAAAAACTCTTCAGAAGCCAGTGCTCCCTCTTTACA
GGGGCTCTTCTGTTTCAGCTTCAAGGGTAGTCAAACCCAGACAATCAAGTCCTCAGCTCCACAACCTAGCAAGTTATACTAAAAAGCACC
ACACGTCCAGTGTTTACTCCATCTCAGAGAGATTGGAGATGAAGCCTGGTCCGCAAGCCCAAGGGCTTGTTATGGAAGCAGCAACACATT
CACAGGGAGACGGCAGCACTGACCTGGACTCGAAGCTGACACAACAGCTGATCGAGTTTGAGAAGAGCTTGGCAGGGCCCGGCACAGAGC
CAGATAAAATTTTACGCCACTTTTCAATCATGGACTTTAACTCTGAGAAGGATATTGTCCGAGGTTCCTCAAAGTTAATCACCGAGCAGG
AGCTGCCGGAAAGGAGAAAGGCCCTAAGGCCACCGCCACCTCGTCCCTGTACTCCGGTATCCACTTCTCCCCATTTGCTGGTTGACCAGA
ACCTAAAACCTGCACCACCCTTGGTGGTGCGACCCTCTCGCCCAGCTCCCCTGCCTCCCTCAGCACAGCAGAGAACGAATGCGGTATCCC
CCAAGCTCCTATCTCGACACCGTCCTACCTGTGAGACCTTAGAAAAGGAGGGCCCTGGTCATATGGGAAGGAGTCTGGACCAGACCTCCC
CATGCCCCTTAGTGCTGGTGAGGATTGAGGAAATGGAGCGGGACTTGGATATGTACAGTAGAGCTCAAGAAGAGCTAAACCTCATGCTGG
AGGAGAAGCAGGATGAATCATCAAGAGCAGAGACCCTCGAGGATCTCAAGTTCTGTGAAAGTAACATTGAAAGTTTGAATATGGAACTCC
AGCAACTAAGAGAAATGACGCTCCTCTCCTCCCAGTCTTCATCACTGGTGGCCCCTTCTGGGTCTGTGTCTGCCGAAAATCCAGAGCAGA
GGATGCTGGAGAAGAGAGCCAAGGTCATAGAAGAACTTCTTCAGACAGAAAGAGACTACATTCGGGATCTGGAAATGTGTATTGAGCGGA
TCATGGTACCCATGCAGCAGGCACAGGTACCAAACATTGATTTTGAGGGACTTTTTGGAAATATGCAGATGGTGATTAAGGTCTCGAAGC
AATTATTGGCTGCTCTGGAAATCAGCGATGCTGTAGGACCTGTGTTTCTTGGTCACCGGGATGAGCTTGAGGGAACATACAAGATTTACT
GCCAGAATCATGATGAGGCCATTGCGCTGCTTGAAATCTACGAGAAGGATGAGAAGATCCAGAAGCATCTTCAGGACTCCTTGGCAGATC
TGAAGAGCCTATACAACGAATGGGGATGCACAAATTATATTAACCTGGGCTCCTTCCTCATCAAACCAGTACAGAGAGTAATGCGTTACC
CGCTGTTGCTAATGGAGTTGCTGAATTCCACCCCAGAATCCCACCCAGATAAAGTGCCTTTAACCAATGCAGTCCTTGCGGTCAAGGAAA
TCAACGTTAACATTAATGAATATAAACGGCGAAAGGACCTGGGTAAGAACAGCATAATTGCTGAAAAGGAGTATGCCCATGCTGAGGAAA
GTGCTTTTCTGACTTACTCCCTAGTCCTCAAGTACCGTAAGGGTGATGAAGATAGCCTTATGGAGAAAATTTCCAAACTGAACATCCACT
CCATCATCAAGAAATCCAACCGAGTTAGCAGTCACCTGAAGCATCTCACTGGCTTTGCTCCTCAGATAAAAGATGAAGTATTTGAAGAAA
CAGAAAAAAACTTCCGAATGCAAGAAAGATTGATTAAGTCTTTTATCCGAGACCTGTCTCTCTACCTCCAGCACATCCGGGAGTCCGCAT
GTGTGAAAGTGGTGGCTGCTGTGAGCATGTGGGATGTGTGCATGGAGAGAGGACACCGGGACCTGGAGCAGTTTGAGAGGGTGCATCGCT
ACATCAGTGACCAGCTCTTCACAAACTTTAAGGAGAGGACAGAGCGGCTTGTCATCTCCCCCTTAAATCAGTTACTGAGCATGTTTACAG
GGCCCCATAAGCTGGTACAGAAACGCTTTGACAAGCTCCTGGACTTCTATAACTGTACAGAACGGGCAGAAAAGCTAAAGGACAAGAAGA
CCCTGGAGGAGCTGCAGTCGGCCCGGAACAACTATGAGGCCCTGAATGCACAGCTGCTGGATGAGCTGCCCAAGTTCCACCAGTACGCCC
AGGGCCTCTTCACCAACTGTGTCCACGGCTATGCTGAAGCCCACTGTGACTTTGTGCACCAGGCTCTGGAGCAATTAAAGCCACTGCTTT
CGTTACTCAAAGTGGCTGGCAGAGAGGGAAACCTTATTGCCATCTTCCACGAAGAGCACAGCAGAGTTCTGCAGCAACTCCAGGTTTTTA
CCTTCTTCCCGGAGTCTCTTCCAGCTACCAAGAAGCCATTTGAGAGGAAAACCATTGACCGCCAGTCTGCTCGAAAGCCACTCCTGGGCC
TGCCAAGTTACATGCTACAGTCAGAAGAACTCCGGGCCTCCCTCCTGGCCAGGTATCCCCCTGAAAAACTCTTCCAGGCAGAACGGAACT
TCAATGCTGCTCAAGACTTGGATGTCTCACTTTTGGAAGGTGACCTGGTGGGTGTGATTAAGAAAAAAGACCCCATGGGCAGCCAGAACC
GCTGGCTGATTGACAATGGAGTCACCAAAGGCTTCGTGTACAGCTCTTTCCTAAAGCCCTACAATCCTCGCCGCAGCCACTCCGATGCCT
CCGTGGGTAGCCACTCCTCCACAGAGTCTGAGCACGGCAGCTCCTCCCCCAGGTTCCCACGCCAGAACAGCGGCAGCACCCTGACCTTCA
ACCCCAGCAGCATGGCTGTATCCTTTACCTCGGGGTCTTGCCAGAAGCAGCCTCAAGATGCATCTCCTCCGCCAAAAGAATGTGACCAAG
GAACTCTCAGTGCATCCCTAAATCCGAGTAATTCAGAGAGTAGTCCTTCCAGATGCCCTTCAGACCCAGACTCCACCTCCCAGCCAAGGT
CAGGGGACTCTGCAGATGTAGCTAGAGATGTAAAGCAACCCACTGCCACGCCGAGGAGCTACCGGAACTTCAGGCATCCAGAAATAGTTG
GCTACTCCGTACCAGGACGAAATGGGCAAAGTCAAGACCTCGTCAAAGGATGTGCAAGAACAGCCCAGGCTCCGGAAGACAGAAGTACAG
AGCCAGATGGCAGTGAGGCAGAAGGCAACCAGCTCCTATTCAGACATATGTGCTTGGTGCTAATAACCAGGAAACAGTAAAATATTTCCA
GGATGCTGATGGATGTGAATTAGCTGAAAACATTACTTATCTGGGTCGTAAAGGTATCTTCACTGGAAGCTCGGGGCTGCAGATTGTGTA
CCTCAGTGGGACAGAATCCTTAAATGAGCCAGTACCAGGTTATAGTTTTAGTCCCAAGGATGTGTCTTCTCTGAGAATGATGCTGTGTAC
AACCTCCCAGTTTAAGGGTGTTGATATCTTGCTCACATCCCCATGGCCCAAGTGTGTGGGGAACTTTGGGAATTCTTCTGGAGAAGTGGA
TACCAAAAAATGTGGTTCTGCTTTGGTTTCCAGTCTTGCCACGGGCTTGAAACCAAGATACCATTTTGCTGCTTTGGAAAAGACCTATTA
TGAGAGGCTTCCATATCGAAACCATATCATTCTACAGGAAAATGCACAGCATGCCACCCGGTTTATAGCTCTGGCAAATGTTGGAAATCC
AGAAAAGAAAAAGTATCTTTACGCGTTCAGTATTGTTCCCATGAAGCTAATGGATGCAGCAGAACTGGTAAAACAGCCTCCGGATGTCAC
TGAAAACCCTTACAGAAAATCTGGGCAGGAAGCATCCATAGGAAAGCAAATTCTTGCCCCTGTGGAAGAATCAGCCTGTCAGTTTTTCTT
TGATTTAAATGAAAAGCAGGGAAGGAAGCGTTCATCCACAGGTAGAGATAGCAAATCTTCTCCTCATCCAAAGCAGCCTCGCAAACCTCC
TCAGCCTCCAGGACCCTGCTGGTTTTGCCTTGCTAGCCCTGAAGTGGAAAAACATTTGGTGGTCAACATCGGCACACATTGCTACCTTGC
CCTGGCCAAAGGAGGCTTATCTGATGACCATGTCCTCATCCTGCCTATTGGACACTACCAGTCAGTGGTGGAGCTTTCAGCAGAGGTGGT
AGAAGAGGTGGAGAAGTATAAGGCCACTCTGAGACGGTTCTTTAAGAGTCGAGGGAAATGGTGTGTTGTATTTGAGAGAAATTATAAGAG
CCATCACCTCCAGCTACAGGTCATTCCTGTCCCAATCAGCTGCTCTACTACTGATGACATTAAAGATGCCTTCATTACCCAGGCACAGGA
GCAGCAGATAGAGCTGTTGGAAATCCCAGAGCACTCTGACATCAAGCAGATTGCACAGCCAGGAGCAGCATATTTTTATGTTGAACTTGA
CACAGGAGAAAAGCTTTTCCACAGAATTAAAAAGAATTTTCCTTTGCAGTTTGGAAGGGAGGTCCTGGCCAGTGAAGCCATCCTTAATGT
TCCTGATAAGTCTGACTGGAGGCAGTGTCAGATCAGCAAGGAAGACGAGGAGACCCTGGCTCGCCGCTTCCGGAAAGACTTTGAGCCCTA
TGACTTTACTCTGGATGACTAAAACAAAGGGAAGAACTTTTTATGAACTCCACAGGAAGTAGTAAAGCTTTTTTTTTTTTTTAATTAAAA
GAATTTTTTTTGAGACAAAGTCTCGCTCTGTCACCCAAGCAGGATTGCAGTGGCATAACTGTGGCTCACTGTAGCCTCAACCTCCTGGGC
TCTAGAGTTCCTCCCACCTCAGCCTCATGAGTAGCTGGGACCACAGGCGCATGCTACCATGCCTGGCAAACTTTTTTGATTTTTTATAGA
GACAGGAGGGTCTCCCTGTGTTGCCCAGGCTGGTCTGTAATGCCTAGGCTCAAGGGATCCTCTGCCTTGGCTTCTTAACCTGCTGGGATT
ACAAGCATGAGACACCATTCCTGGCCTAGAAGCCTATTTTTAAAGAAACTACAATCTCCCATGGGGACTGTTTCCCTGCCTCTTTTGTGC
AGTCCCATGGAACTTGCCTACAGCAAGAGGCCTAAGATTGAATCTTTTTGGGGAAAAGTCATTCTAGGATGAAAATCCTATGTTAAGGCC
GGGCGCAGTGGCTCACGCCTGTAATCCCAGTACTTTGGGAAGCCGAGGCAGGTGGATCACCTGAGGTGAGGAGTTTGAGACCAGCCTGGC
CAACATGGTGAAACCCCGTCTTTACTAAAGCTACAAAAATTAGCTGGGCGTGGTGCCAGGCACTTGTAATCCCAGCTACTCAGGAGGCTG
AGGCAGGAGAATTGCTTGAGCCTGGGAGGTGGAGGTTGCAGTGAGCCAAGATCGCTCCATTGCACTCCAGCCTGGGTGACAGTGAAACTC
CATCTCAAAAATAAAAGAATAAAAGTATGTCTGTCATCCAGCTCCTATGTCTGTTATCCAGCTCCAAGTACAGCTTGTGTATATCAACAT

>23683_23683_2_DNMBP-CWF19L1_DNMBP_chr10_101639568_ENST00000342239_CWF19L1_chr10_102020076_ENST00000354105_length(amino acids)=1555AA_BP=1540
MEAGSVVRAIFDFCPSVSEELPLFVGDIIEVLAVVDEFWLLGKKEDVTGQFPSSFVEIVTIPSLKEGERLFVCICEFTSQELDNLPLHRG
DLVILDGIPTAGWLQGRSCWGARGFFPSSCVRELCLSSQSRQWHSQSALFQIPEYSMGQARALMGLSAQLDEELDFREGDVITIIGVPEP
GWFEGELEGRRGIFPEGFVELLGPLRTVDESVSSGNQDDCIVNGEVDTPVGEEEIGPDEDEEEPGTYGVALYRFQALEPNELDFEVGDKI
RILATLEDGWLEGSLKGRTGIFPYRFVKLCPDTRVEETMALPQEGSLARIPETSLDCLENTLGVEEQRHETSDHEAEEPDCIISEAPTSP
LGHLTSEYDTDRNSYQDEDTAGGPPRSPGVEWEMPLATDSPTSDPTEVVNGISSQPQVPFHPNLQKSQYYSTVGGSHPHSEQYPDLLPLE
ARTRDYASLPPKRMYSQLKTLQKPVLPLYRGSSVSASRVVKPRQSSPQLHNLASYTKKHHTSSVYSISERLEMKPGPQAQGLVMEAATHS
QGDGSTDLDSKLTQQLIEFEKSLAGPGTEPDKILRHFSIMDFNSEKDIVRGSSKLITEQELPERRKALRPPPPRPCTPVSTSPHLLVDQN
LKPAPPLVVRPSRPAPLPPSAQQRTNAVSPKLLSRHRPTCETLEKEGPGHMGRSLDQTSPCPLVLVRIEEMERDLDMYSRAQEELNLMLE
EKQDESSRAETLEDLKFCESNIESLNMELQQLREMTLLSSQSSSLVAPSGSVSAENPEQRMLEKRAKVIEELLQTERDYIRDLEMCIERI
MVPMQQAQVPNIDFEGLFGNMQMVIKVSKQLLAALEISDAVGPVFLGHRDELEGTYKIYCQNHDEAIALLEIYEKDEKIQKHLQDSLADL
KSLYNEWGCTNYINLGSFLIKPVQRVMRYPLLLMELLNSTPESHPDKVPLTNAVLAVKEINVNINEYKRRKDLGKNSIIAEKEYAHAEES
AFLTYSLVLKYRKGDEDSLMEKISKLNIHSIIKKSNRVSSHLKHLTGFAPQIKDEVFEETEKNFRMQERLIKSFIRDLSLYLQHIRESAC
VKVVAAVSMWDVCMERGHRDLEQFERVHRYISDQLFTNFKERTERLVISPLNQLLSMFTGPHKLVQKRFDKLLDFYNCTERAEKLKDKKT
LEELQSARNNYEALNAQLLDELPKFHQYAQGLFTNCVHGYAEAHCDFVHQALEQLKPLLSLLKVAGREGNLIAIFHEEHSRVLQQLQVFT
FFPESLPATKKPFERKTIDRQSARKPLLGLPSYMLQSEELRASLLARYPPEKLFQAERNFNAAQDLDVSLLEGDLVGVIKKKDPMGSQNR
WLIDNGVTKGFVYSSFLKPYNPRRSHSDASVGSHSSTESEHGSSSPRFPRQNSGSTLTFNPSSMAVSFTSGSCQKQPQDASPPPKECDQG
TLSASLNPSNSESSPSRCPSDPDSTSQPRSGDSADVARDVKQPTATPRSYRNFRHPEIVGYSVPGRNGQSQDLVKGCARTAQAPEDRSTE

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Fusion Gene PPI Analysis for DNMBP-CWF19L1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DNMBP-CWF19L1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DNMBP-CWF19L1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource