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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DPP8-TRPM1 (FusionGDB2 ID:24043)

Fusion Gene Summary for DPP8-TRPM1

check button Fusion gene summary
Fusion gene informationFusion gene name: DPP8-TRPM1
Fusion gene ID: 24043
HgeneTgene
Gene symbol

DPP8

TRPM1

Gene ID

54878

4308

Gene namedipeptidyl peptidase 8transient receptor potential cation channel subfamily M member 1
SynonymsDP8|DPRP-1|DPRP1|MST097|MSTP097|MSTP135|MSTP141CSNB1C|LTRPC1|MLSN1
Cytomap

15q22.31

15q13.3

Type of geneprotein-codingprotein-coding
Descriptiondipeptidyl peptidase 8DPP VIIIdipeptidyl peptidase IV-related protein 1dipeptidyl peptidase VIIIprolyl dipeptidase DPP8transient receptor potential cation channel subfamily M member 1long transient receptor potential channel 1melastatin-1transient receptor potential melastatin family
Modification date2020031320200313
UniProtAcc

Q6V1X1

.
Ensembl transtripts involved in fusion geneENST00000300141, ENST00000321118, 
ENST00000321147, ENST00000341861, 
ENST00000358939, ENST00000559233, 
ENST00000339244, ENST00000560048, 
ENST00000559179, ENST00000256552, 
ENST00000397795, ENST00000542188, 
Fusion gene scores* DoF score7 X 7 X 4=1965 X 4 X 4=80
# samples 86
** MAII scorelog2(8/196*10)=-1.29278174922785
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(6/80*10)=-0.415037499278844
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DPP8 [Title/Abstract] AND TRPM1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDPP8(65766547)-TRPM1(31327877), # samples:1
Anticipated loss of major functional domain due to fusion event.DPP8-TRPM1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
DPP8-TRPM1 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
DPP8-TRPM1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneTRPM1

GO:0060402

calcium ion transport into cytosol

23452348


check buttonFusion gene breakpoints across DPP8 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TRPM1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-FX-A3TO-01ADPP8chr15

65766547

-TRPM1chr15

31327877

-


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Fusion Gene ORF analysis for DPP8-TRPM1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000300141ENST00000559179DPP8chr15

65766547

-TRPM1chr15

31327877

-
5CDS-intronENST00000321118ENST00000559179DPP8chr15

65766547

-TRPM1chr15

31327877

-
5CDS-intronENST00000321147ENST00000559179DPP8chr15

65766547

-TRPM1chr15

31327877

-
5CDS-intronENST00000341861ENST00000559179DPP8chr15

65766547

-TRPM1chr15

31327877

-
5CDS-intronENST00000358939ENST00000559179DPP8chr15

65766547

-TRPM1chr15

31327877

-
5CDS-intronENST00000559233ENST00000559179DPP8chr15

65766547

-TRPM1chr15

31327877

-
Frame-shiftENST00000300141ENST00000256552DPP8chr15

65766547

-TRPM1chr15

31327877

-
Frame-shiftENST00000300141ENST00000397795DPP8chr15

65766547

-TRPM1chr15

31327877

-
Frame-shiftENST00000300141ENST00000542188DPP8chr15

65766547

-TRPM1chr15

31327877

-
Frame-shiftENST00000321118ENST00000256552DPP8chr15

65766547

-TRPM1chr15

31327877

-
Frame-shiftENST00000321118ENST00000397795DPP8chr15

65766547

-TRPM1chr15

31327877

-
Frame-shiftENST00000321118ENST00000542188DPP8chr15

65766547

-TRPM1chr15

31327877

-
Frame-shiftENST00000321147ENST00000256552DPP8chr15

65766547

-TRPM1chr15

31327877

-
Frame-shiftENST00000321147ENST00000397795DPP8chr15

65766547

-TRPM1chr15

31327877

-
Frame-shiftENST00000321147ENST00000542188DPP8chr15

65766547

-TRPM1chr15

31327877

-
Frame-shiftENST00000358939ENST00000256552DPP8chr15

65766547

-TRPM1chr15

31327877

-
Frame-shiftENST00000358939ENST00000397795DPP8chr15

65766547

-TRPM1chr15

31327877

-
Frame-shiftENST00000358939ENST00000542188DPP8chr15

65766547

-TRPM1chr15

31327877

-
In-frameENST00000341861ENST00000256552DPP8chr15

65766547

-TRPM1chr15

31327877

-
In-frameENST00000341861ENST00000397795DPP8chr15

65766547

-TRPM1chr15

31327877

-
In-frameENST00000341861ENST00000542188DPP8chr15

65766547

-TRPM1chr15

31327877

-
In-frameENST00000559233ENST00000256552DPP8chr15

65766547

-TRPM1chr15

31327877

-
In-frameENST00000559233ENST00000397795DPP8chr15

65766547

-TRPM1chr15

31327877

-
In-frameENST00000559233ENST00000542188DPP8chr15

65766547

-TRPM1chr15

31327877

-
intron-3CDSENST00000339244ENST00000256552DPP8chr15

65766547

-TRPM1chr15

31327877

-
intron-3CDSENST00000339244ENST00000397795DPP8chr15

65766547

-TRPM1chr15

31327877

-
intron-3CDSENST00000339244ENST00000542188DPP8chr15

65766547

-TRPM1chr15

31327877

-
intron-3CDSENST00000560048ENST00000256552DPP8chr15

65766547

-TRPM1chr15

31327877

-
intron-3CDSENST00000560048ENST00000397795DPP8chr15

65766547

-TRPM1chr15

31327877

-
intron-3CDSENST00000560048ENST00000542188DPP8chr15

65766547

-TRPM1chr15

31327877

-
intron-intronENST00000339244ENST00000559179DPP8chr15

65766547

-TRPM1chr15

31327877

-
intron-intronENST00000560048ENST00000559179DPP8chr15

65766547

-TRPM1chr15

31327877

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000341861DPP8chr1565766547-ENST00000397795TRPM1chr1531327877-62333165158154711296
ENST00000341861DPP8chr1565766547-ENST00000256552TRPM1chr1531327877-59603165158154711296
ENST00000341861DPP8chr1565766547-ENST00000542188TRPM1chr1531327877-59443165158154711296
ENST00000559233DPP8chr1565766547-ENST00000397795TRPM1chr1531327877-4764169611240021296
ENST00000559233DPP8chr1565766547-ENST00000256552TRPM1chr1531327877-4491169611240021296
ENST00000559233DPP8chr1565766547-ENST00000542188TRPM1chr1531327877-4475169611240021296

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000341861ENST00000397795DPP8chr1565766547-TRPM1chr1531327877-0.0032336690.9967663
ENST00000341861ENST00000256552DPP8chr1565766547-TRPM1chr1531327877-0.0037727620.99622726
ENST00000341861ENST00000542188DPP8chr1565766547-TRPM1chr1531327877-0.0038975390.99610245
ENST00000559233ENST00000397795DPP8chr1565766547-TRPM1chr1531327877-0.0010227640.9989773
ENST00000559233ENST00000256552DPP8chr1565766547-TRPM1chr1531327877-0.0015841620.9984158
ENST00000559233ENST00000542188DPP8chr1565766547-TRPM1chr1531327877-0.0017019720.998298

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Fusion Genomic Features for DPP8-TRPM1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for DPP8-TRPM1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr15:65766547/chr15:31327877)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DPP8

Q6V1X1

.
FUNCTION: Dipeptidyl peptidase that cleaves off N-terminal dipeptides from proteins having a Pro or Ala residue at position 2. {ECO:0000269|PubMed:11012666, ECO:0000269|PubMed:12534281, ECO:0000269|PubMed:12662155, ECO:0000269|PubMed:15039077, ECO:0000269|PubMed:15664838, ECO:0000269|PubMed:20536396, ECO:0000305|PubMed:29382749}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTRPM1chr15:65766547chr15:31327877ENST0000025655219281182_12408571626.0Coiled coilOntology_term=ECO:0000255
TgeneTRPM1chr15:65766547chr15:31327877ENST0000039779518271182_12408351604.0Coiled coilOntology_term=ECO:0000255
TgeneTRPM1chr15:65766547chr15:31327877ENST0000054218818271182_12408741643.0Coiled coilOntology_term=ECO:0000255
TgeneTRPM1chr15:65766547chr15:31327877ENST00000559179031182_12400137.0Coiled coilOntology_term=ECO:0000255
TgeneTRPM1chr15:65766547chr15:31327877ENST0000025655219281076_11058571626.0Topological domainExtracellular
TgeneTRPM1chr15:65766547chr15:31327877ENST0000025655219281127_16038571626.0Topological domainCytoplasmic
TgeneTRPM1chr15:65766547chr15:31327877ENST000002565521928919_9288571626.0Topological domainCytoplasmic
TgeneTRPM1chr15:65766547chr15:31327877ENST000002565521928950_9618571626.0Topological domainExtracellular
TgeneTRPM1chr15:65766547chr15:31327877ENST000002565521928983_10548571626.0Topological domainCytoplasmic
TgeneTRPM1chr15:65766547chr15:31327877ENST0000039779518271076_11058351604.0Topological domainExtracellular
TgeneTRPM1chr15:65766547chr15:31327877ENST0000039779518271127_16038351604.0Topological domainCytoplasmic
TgeneTRPM1chr15:65766547chr15:31327877ENST000003977951827852_8978351604.0Topological domainExtracellular
TgeneTRPM1chr15:65766547chr15:31327877ENST000003977951827919_9288351604.0Topological domainCytoplasmic
TgeneTRPM1chr15:65766547chr15:31327877ENST000003977951827950_9618351604.0Topological domainExtracellular
TgeneTRPM1chr15:65766547chr15:31327877ENST000003977951827983_10548351604.0Topological domainCytoplasmic
TgeneTRPM1chr15:65766547chr15:31327877ENST0000054218818271076_11058741643.0Topological domainExtracellular
TgeneTRPM1chr15:65766547chr15:31327877ENST0000054218818271127_16038741643.0Topological domainCytoplasmic
TgeneTRPM1chr15:65766547chr15:31327877ENST000005421881827919_9288741643.0Topological domainCytoplasmic
TgeneTRPM1chr15:65766547chr15:31327877ENST000005421881827950_9618741643.0Topological domainExtracellular
TgeneTRPM1chr15:65766547chr15:31327877ENST000005421881827983_10548741643.0Topological domainCytoplasmic
TgeneTRPM1chr15:65766547chr15:31327877ENST00000559179031076_11050137.0Topological domainExtracellular
TgeneTRPM1chr15:65766547chr15:31327877ENST00000559179031127_16030137.0Topological domainCytoplasmic
TgeneTRPM1chr15:65766547chr15:31327877ENST00000559179031_8300137.0Topological domainCytoplasmic
TgeneTRPM1chr15:65766547chr15:31327877ENST0000055917903852_8970137.0Topological domainExtracellular
TgeneTRPM1chr15:65766547chr15:31327877ENST0000055917903919_9280137.0Topological domainCytoplasmic
TgeneTRPM1chr15:65766547chr15:31327877ENST0000055917903950_9610137.0Topological domainExtracellular
TgeneTRPM1chr15:65766547chr15:31327877ENST0000055917903983_10540137.0Topological domainCytoplasmic
TgeneTRPM1chr15:65766547chr15:31327877ENST0000025655219281055_10758571626.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST0000025655219281106_11268571626.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST000002565521928898_9188571626.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST000002565521928929_9498571626.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST000002565521928962_9828571626.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST0000039779518271055_10758351604.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST0000039779518271106_11268351604.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST000003977951827898_9188351604.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST000003977951827929_9498351604.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST000003977951827962_9828351604.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST0000054218818271055_10758741643.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST0000054218818271106_11268741643.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST000005421881827898_9188741643.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST000005421881827929_9498741643.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST000005421881827962_9828741643.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST00000559179031055_10750137.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST00000559179031106_11260137.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST0000055917903831_8510137.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST0000055917903898_9180137.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST0000055917903929_9490137.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST0000055917903962_9820137.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneTRPM1chr15:65766547chr15:31327877ENST0000025655219281_8308571626.0Topological domainCytoplasmic
TgeneTRPM1chr15:65766547chr15:31327877ENST000002565521928852_8978571626.0Topological domainExtracellular
TgeneTRPM1chr15:65766547chr15:31327877ENST0000039779518271_8308351604.0Topological domainCytoplasmic
TgeneTRPM1chr15:65766547chr15:31327877ENST0000054218818271_8308741643.0Topological domainCytoplasmic
TgeneTRPM1chr15:65766547chr15:31327877ENST000005421881827852_8978741643.0Topological domainExtracellular
TgeneTRPM1chr15:65766547chr15:31327877ENST000002565521928831_8518571626.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST000003977951827831_8518351604.0TransmembraneHelical
TgeneTRPM1chr15:65766547chr15:31327877ENST000005421881827831_8518741643.0TransmembraneHelical


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Fusion Gene Sequence for DPP8-TRPM1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>24043_24043_1_DPP8-TRPM1_DPP8_chr15_65766547_ENST00000341861_TRPM1_chr15_31327877_ENST00000256552_length(transcript)=5960nt_BP=3165nt
AGATTCCGAGTCAACCACCGTTCACTGGGCGCCCCTTGAGCTCTGGGCGCTGGCCTCCTGGCTTCCACGTCCGTTATCTTAATTGAGTCT
CGCTGGGGTTGGGAGGCCGGGTATTGTCAGCGCTTACAGATGAGGAAACGGAAGCCCACAGAGGCGAAGGGATTTTCCTTAAGTCCGACT
TGGCAGATGGGCTTCGGCCTCAGATTTTCTGGTTTTTCAGCTGGTGGTCTTTTTTCTCTCCTGCCTCATGCTAGGTCGATTCCCTCCCTG
CTCACTGCCCTCTCCCATTCTGTTCCACCCACTCGCAGCAGGACACTTTCCTTTCCTGCCACACCTGTCTTCTCACACACTTTTCTTCTA
AGACTTGGCATTCCTCCCATCTCTCTTCTCAATATTCTCTGCTATGCCTCTCCTCTTGTTCCTCATTCATAGTTTTTCAAGGTCTTTGCC
CCCTCTGTGCTATTGAATCTCTCAACTAGGTGTGGACCCTAAAGAATGAGATAGCTAGGCTTCAGTGAGGCTTTAGGTGTTTAAGTGGAC
GGCTGTTTGGCCCTTGAGTTAAAAATTAAGGAATTTCACTTGAGTGGATCCAAACTCAAGAGTCCTAAAGCTATTTTCTGAGTCAACATG
CTCTATTTCTGAGTGAGGGGCTTAGTGCTATGAGGTGTCTTGACATCTTAGTCCATTGTTGCTGTGCTGGCATAACCTCGCTGTTTTTCC
TGCACTTGCCACTTAGCTTTTCCCACCCCATCCCTTCATCACCTACTTGGGCTATGGGAGCCCAAAATTAAAACTTATAGAGTAACAGAT
GTAATAGCAGACCTTCCTTTTTTTTTTTTTCCTAAGCCAGAATTTCAACAAGTTTAATGCTTCTTTTTCCAGAAAAGTTACCTATTTAAA
TTATTCTCAGAGTAATGCAGCAAGAAAATGGAATGCACTTAAGATGAATAGAAAATTGTTTATCTCGTGAAAAGTCTTAAGTTATTAAAT
TCAAGTTAATTCCCTTTCTGCAAAAATGGCCTGTAACTCTTACTGGCTATCCTCCTGAGTTAATTCTATCTCCATCCAGCTTGATATGAC
ATTATTATGTAAAAGAGGAACAGGAATAGGCACATAAAAATAAATTTTATTAATCATATGCCGTTTTTGATGATTTGCAATAGTCACTGA
GTAACTTCACATCTGTATGCCTTTTGTAACTTTTTAAAGCCTTTCCATGGTTTTCCTTTGTCTGGACACCAAAGTTTGCTATGTTAGGAT
ATTCTTTTGACTATATTGGGCTACACATCTCTGAAATAAAATAATTCTTGAATTCTGATAACATAAAACGCAGATACAAAATAATGTAGG
CATTATATATTGCCCCAAAAAGTGATATTTTGGTATCAGTTTTAACTACTATTTTGGGGCTTCTCTTTTTGGCCACATATGGTCCATCTT
AATGATCAAAGTCTTATCTTATTTCATTATCCTGGTGAGCAGGCTTTGATGGTGAGGAAAGGAAAGATTCCTGTGAGAAGAGCAGGATGA
GCAGAGGGATTCTATGCTTGAAGTCGAGTCACTTGAAAAAGATCTCTTTGAATGTGGAAGAGATCTGAGCAGATGAAAATAAAATCAGGA
AAATGCAACATGGCAGCAGCAATGGAAACAGAACAGCTGGGTGTTGAGATATTTGAAACTGCGGACTGTGAGGAGAATATTGAATCACAG
GATCGGCCTAAATTGGAGCCTTTTTATGTTGAGCGGTATTCCTGGAGTCAGCTTAAAAAGCTGCTTGCCGATACCAGAAAATATCATGGC
TACATGATGGCTAAGGCACCACATGATTTCATGTTTGTGAAGAGGAATGATCCAGATGGACCTCATTCAGACAGAATCTATTACCTTGCC
ATGTCTGGTGAGAACAGAGAAAATACACTGTTTTATTCTGAAATTCCCAAAACTATCAATAGAGCAGCAGTCTTAATGCTCTCTTGGAAG
CCTCTTTTGGATCTTTTTCAGGCAACACTGGACTATGGAATGTATTCTCGAGAAGAAGAACTATTAAGAGAAAGAAAACGCATTGGAACA
GTCGGAATTGCTTCTTACGATTATCACCAAGGAAGTGGAACATTTCTGTTTCAAGCCGGTAGTGGAATTTATCACGTAAAAGATGGAGGG
CCACAAGGATTTACGCAACAACCTTTAAGGCCCAATCTAGTGGAAACTAGTTGTCCCAACATACGGATGGATCCAAAATTATGCCCTGCT
GATCCAGACTGGATTGCTTTTATACATAGCAACGATATTTGGATATCTAACATCGTAACCAGAGAAGAAAGGAGACTCACTTATGTGCAC
AATGAGCTAGCCAACATGGAAGAAGATGCCAGATCAGCTGGAGTCGCTACCTTTGTTCTCCAAGAAGAATTTGATAGATATTCTGGCTAT
TGGTGGTGTCCAAAAGCTGAAACAACTCCCAGTGGTGGTAAAATTCTTAGAATTCTATATGAAGAAAATGATGAATCTGAGGTGGAAATT
ATTCATGTTACATCCCCTATGTTGGAAACAAGGAGGGCAGATTCATTCCGTTATCCTAAAACAGGTACAGCAAATCCTAAAGTCACTTTT
AAGATGTCAGAAATAATGATTGATGCTGAAGGAAGGATCATAGATGTCATAGATAAGGAACTAATTCAACCTTTTGAGATTCTATTTGAA
GGAGTTGAATATATTGCCAGAGCTGGATGGACTCCTGAGGGAAAATATGCTTGGTCCATCCTACTAGATCGCTCCCAGACTCGCCTACAG
ATAGTGTTGATCTCACCTGAATTATTTATCCCAGTAGAAGATGATGTTATGGAAAGGCAGAGACTCATTGAGTCAGTGCCTGATTCTGTG
ACGCCACTAATTATCTATGAAGAAACAACAGACATCTGGATAAATATCCATGACATCTTTCATGTTTTTCCCCAAAGTCACGAAGAGGAA
ATTGAGTTTATTTTTGCCTCTGAATGCAAAACAGGTTTCCGTCATTTATACAAAATTACATCTATTTTAAAGGAAAGCAAATATAAACGA
TCCAGTGGTGGGCTGCCTGCTCCAAGTGATTTCAAGTGTCCTATCAAAGAGGAGATAGCAATTACCAGTGGTGAATGGGAAGTTCTTGGC
CGGCATGGATCTAATATATCATACTTGGGCTACCTGCTGCTGTTTAACTACGTCATCCTGGTGCGGATGGATGGCTGGCCGTCCCTCCAG
GAGTGGATCGTCATCTCCTACATCGTGAGCCTGGCGTTAGAGAAGATACGAGAGATCCTCATGTCAGAACCAGGCAAACTCAGCCAGAAA
ATCAAAGTTTGGCTTCAGGAGTACTGGAACATCACAGATCTCGTGGCCATTTCCACATTCATGATTGGAGCAATTCTTCGCCTACAGAAC
CAGCCCTACATGGGCTATGGCCGGGTGATCTACTGTGTGGATATCATCTTCTGGTACATCCGTGTCCTGGACATCTTTGGTGTCAACAAG
TATCTGGGGCCATACGTGATGATGATTGGAAAGATGATGATCGACATGCTGTACTTTGTGGTCATCATGCTGGTCGTGCTCATGAGTTTC
GGAGTAGCCCGTCAAGCCATTCTGCATCCAGAGGAGAAGCCCTCTTGGAAACTGGCCCGAAACATCTTCTACATGCCCTACTGGATGATC
TATGGAGAGGTGTTTGCAGACCAGATAGACCTCTACGCCATGGAAATTAATCCTCCTTGTGGTGAGAACCTATATGATGAGGAGGGCAAG
CGGCTTCCTCCCTGTATCCCCGGCGCCTGGCTCACTCCAGCACTCATGGCGTGCTATCTACTGGTCGCCAACATCCTGCTGGTGAACCTG
CTGATTGCTGTGTTCAACAATACCTTCTTTGAAGTAAAATCAATATCCAACCAGGTGTGGAAGTTCCAGCGATATCAGCTGATTATGACA
TTTCATGACAGGCCAGTCCTGCCCCCACCGATGATCATTTTAAGCCACATCTACATCATCATTATGCGTCTCAGCGGCCGCTGCAGGAAA
AAGAGAGAAGGGGACCAAGAGGAACGGGATCGTGGATTGAAGCTCTTCCTTAGCGACGAGGAGCTAAAGAGGCTGCATGAGTTCGAGGAG
CAGTGCGTGCAGGAGCACTTCCGGGAGAAGGAGGATGAGCAGCAGTCGTCCAGCGACGAGCGCATCCGGGTCACTTCTGAAAGAGTTGAA
AATATGTCAATGAGGTTGGAAGAAATCAATGAAAGAGAAACTTTTATGAAAACTTCCCTGCAGACTGTTGACCTTCGACTTGCTCAGCTA
GAAGAATTATCTAACAGAATGGTGAATGCTCTTGAAAATCTTGCGGGAATCGACAGGTCTGACCTGATCCAGGCACGGTCCCGGGCTTCT
TCTGAATGTGAGGCAACGTATCTTCTCCGGCAAAGCAGCATCAATAGCGCTGATGGCTACAGCTTGTATCGATATCATTTTAACGGAGAA
GAGTTATTATTTGAGGATACATCTCTCTCCACGTCACCAGGGACAGGAGTCAGGAAAAAAACCTGTTCCTTCCGTATAAAGGAAGAGAAG
GACGTGAAAACGCACCTAGTCCCAGAATGTCAGAACAGTCTTCACCTTTCACTGGGCACAAGCACATCAGCAACCCCAGATGGCAGTCAC
CTTGCAGTAGATGACTTAAAGAACGCTGAAGAGTCAAAATTAGGTCCAGATATTGGGATTTCAAAGGAAGATGATGAAAGACAGACAGAC
TCTAAAAAAGAAGAAACTATTTCCCCAAGTTTAAATAAAACAGATGTGATACATGGACAGGACAAATCAGATGTTCAAAACACTCAGCTA
ACAGTGGAAACGACAAATATAGAAGGCACTATTTCCTATCCCCTGGAAGAAACCAAAATTACACGCTATTTCCCCGATGAAACGATCAAT
GCTTGTAAAACAATGAAGTCCAGAAGCTTCGTCTATTCCCGGGGAAGAAAGCTGGTCGGTGGGGTTAACCAGGATGTAGAGTACAGTTCA
ATCACGGACCAGCAATTGACGACGGAATGGCAATGCCAAGTTCAAAAGATCACGCGCTCTCATAGCACAGATATTCCTTACATTGTGTCG
GAAGCTGCAGTGCAAGCTGAGCATAAAGAGCAGTTTGCAGATATGCAAGATGAACACCATGTCGCTGAAGCAATTCCTCGAATCCCTCGC
TTGTCCCTAACCATTACTGACAGAAATGGGATGGAAAACTTACTGTCTGTGAAGCCAGATCAAACTTTGGGATTCCCATCTCTCAGGTCA
AAAAGTTTACATGGACATCCTAGGAATGTGAAATCCATTCAGGGAAAGTTAGACAGATCTGGACATGCCAGTAGTGTAAGCAGCTTAGTA
ATTGTGTCTGGAATGACAGCAGAAGAAAAAAAGGTTAAGAAAGAGAAAGCTTCCACAGAAACTGAATGCTAGTCTGTTTTGTTTCTTTAA
TTTTTTTTTTTAACAGTCAGAACCACTAATGGGTGTCATCTTGGCCATCTAAACATCATCAATTTCTAAAAACATTTTCCTTAAAAAATT
TTGGAAATTCAGACTTGATTTACAATTTAATGCACTAAAAGTAGTATTTTGTTAGCATATGTTAGTAGGCTTAGTTTTTTCAGTTGCAGT
AGTATCAAATGAAAGTGATGATACTGTAACGAAGATAAATTGGCTAATCAGTATACAAGATTATACAATCTCTTTATTACTGAGGGCCAC
CAAATAGCCTAGGAAGTGCCCTCGAGCACTGAAGTCACCATTAGGTCACTTAAGAAGTAAGCAACTAGCTGGGCACAGTGGCTCATGCCT
GTAATCCTAGCACTTTGGGAGGCCAAGGCAGAAAGATAGCTTGAGTCCAGGAGTTTGAGACCAGCCTGGGCAACATAGTGATACCCCATC

>24043_24043_1_DPP8-TRPM1_DPP8_chr15_65766547_ENST00000341861_TRPM1_chr15_31327877_ENST00000256552_length(amino acids)=1296AA_BP=528
MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRND
PDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLF
QAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVAT
FVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVI
DKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIH
DIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNISYLGYLLLFNY
VILVRMDGWPSLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAISTFMIGAILRLQNQPYMGYGRVIYCVDIIF
WYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQIDLYAMEIN
PPCGENLYDEEGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPMIILSHI
YIIIMRLSGRCRKKREGDQEERDRGLKLFLSDEELKRLHEFEEQCVQEHFREKEDEQQSSSDERIRVTSERVENMSMRLEEINERETFMK
TSLQTVDLRLAQLEELSNRMVNALENLAGIDRSDLIQARSRASSECEATYLLRQSSINSADGYSLYRYHFNGEELLFEDTSLSTSPGTGV
RKKTCSFRIKEEKDVKTHLVPECQNSLHLSLGTSTSATPDGSHLAVDDLKNAEESKLGPDIGISKEDDERQTDSKKEETISPSLNKTDVI
HGQDKSDVQNTQLTVETTNIEGTISYPLEETKITRYFPDETINACKTMKSRSFVYSRGRKLVGGVNQDVEYSSITDQQLTTEWQCQVQKI
TRSHSTDIPYIVSEAAVQAEHKEQFADMQDEHHVAEAIPRIPRLSLTITDRNGMENLLSVKPDQTLGFPSLRSKSLHGHPRNVKSIQGKL

--------------------------------------------------------------
>24043_24043_2_DPP8-TRPM1_DPP8_chr15_65766547_ENST00000341861_TRPM1_chr15_31327877_ENST00000397795_length(transcript)=6233nt_BP=3165nt
AGATTCCGAGTCAACCACCGTTCACTGGGCGCCCCTTGAGCTCTGGGCGCTGGCCTCCTGGCTTCCACGTCCGTTATCTTAATTGAGTCT
CGCTGGGGTTGGGAGGCCGGGTATTGTCAGCGCTTACAGATGAGGAAACGGAAGCCCACAGAGGCGAAGGGATTTTCCTTAAGTCCGACT
TGGCAGATGGGCTTCGGCCTCAGATTTTCTGGTTTTTCAGCTGGTGGTCTTTTTTCTCTCCTGCCTCATGCTAGGTCGATTCCCTCCCTG
CTCACTGCCCTCTCCCATTCTGTTCCACCCACTCGCAGCAGGACACTTTCCTTTCCTGCCACACCTGTCTTCTCACACACTTTTCTTCTA
AGACTTGGCATTCCTCCCATCTCTCTTCTCAATATTCTCTGCTATGCCTCTCCTCTTGTTCCTCATTCATAGTTTTTCAAGGTCTTTGCC
CCCTCTGTGCTATTGAATCTCTCAACTAGGTGTGGACCCTAAAGAATGAGATAGCTAGGCTTCAGTGAGGCTTTAGGTGTTTAAGTGGAC
GGCTGTTTGGCCCTTGAGTTAAAAATTAAGGAATTTCACTTGAGTGGATCCAAACTCAAGAGTCCTAAAGCTATTTTCTGAGTCAACATG
CTCTATTTCTGAGTGAGGGGCTTAGTGCTATGAGGTGTCTTGACATCTTAGTCCATTGTTGCTGTGCTGGCATAACCTCGCTGTTTTTCC
TGCACTTGCCACTTAGCTTTTCCCACCCCATCCCTTCATCACCTACTTGGGCTATGGGAGCCCAAAATTAAAACTTATAGAGTAACAGAT
GTAATAGCAGACCTTCCTTTTTTTTTTTTTCCTAAGCCAGAATTTCAACAAGTTTAATGCTTCTTTTTCCAGAAAAGTTACCTATTTAAA
TTATTCTCAGAGTAATGCAGCAAGAAAATGGAATGCACTTAAGATGAATAGAAAATTGTTTATCTCGTGAAAAGTCTTAAGTTATTAAAT
TCAAGTTAATTCCCTTTCTGCAAAAATGGCCTGTAACTCTTACTGGCTATCCTCCTGAGTTAATTCTATCTCCATCCAGCTTGATATGAC
ATTATTATGTAAAAGAGGAACAGGAATAGGCACATAAAAATAAATTTTATTAATCATATGCCGTTTTTGATGATTTGCAATAGTCACTGA
GTAACTTCACATCTGTATGCCTTTTGTAACTTTTTAAAGCCTTTCCATGGTTTTCCTTTGTCTGGACACCAAAGTTTGCTATGTTAGGAT
ATTCTTTTGACTATATTGGGCTACACATCTCTGAAATAAAATAATTCTTGAATTCTGATAACATAAAACGCAGATACAAAATAATGTAGG
CATTATATATTGCCCCAAAAAGTGATATTTTGGTATCAGTTTTAACTACTATTTTGGGGCTTCTCTTTTTGGCCACATATGGTCCATCTT
AATGATCAAAGTCTTATCTTATTTCATTATCCTGGTGAGCAGGCTTTGATGGTGAGGAAAGGAAAGATTCCTGTGAGAAGAGCAGGATGA
GCAGAGGGATTCTATGCTTGAAGTCGAGTCACTTGAAAAAGATCTCTTTGAATGTGGAAGAGATCTGAGCAGATGAAAATAAAATCAGGA
AAATGCAACATGGCAGCAGCAATGGAAACAGAACAGCTGGGTGTTGAGATATTTGAAACTGCGGACTGTGAGGAGAATATTGAATCACAG
GATCGGCCTAAATTGGAGCCTTTTTATGTTGAGCGGTATTCCTGGAGTCAGCTTAAAAAGCTGCTTGCCGATACCAGAAAATATCATGGC
TACATGATGGCTAAGGCACCACATGATTTCATGTTTGTGAAGAGGAATGATCCAGATGGACCTCATTCAGACAGAATCTATTACCTTGCC
ATGTCTGGTGAGAACAGAGAAAATACACTGTTTTATTCTGAAATTCCCAAAACTATCAATAGAGCAGCAGTCTTAATGCTCTCTTGGAAG
CCTCTTTTGGATCTTTTTCAGGCAACACTGGACTATGGAATGTATTCTCGAGAAGAAGAACTATTAAGAGAAAGAAAACGCATTGGAACA
GTCGGAATTGCTTCTTACGATTATCACCAAGGAAGTGGAACATTTCTGTTTCAAGCCGGTAGTGGAATTTATCACGTAAAAGATGGAGGG
CCACAAGGATTTACGCAACAACCTTTAAGGCCCAATCTAGTGGAAACTAGTTGTCCCAACATACGGATGGATCCAAAATTATGCCCTGCT
GATCCAGACTGGATTGCTTTTATACATAGCAACGATATTTGGATATCTAACATCGTAACCAGAGAAGAAAGGAGACTCACTTATGTGCAC
AATGAGCTAGCCAACATGGAAGAAGATGCCAGATCAGCTGGAGTCGCTACCTTTGTTCTCCAAGAAGAATTTGATAGATATTCTGGCTAT
TGGTGGTGTCCAAAAGCTGAAACAACTCCCAGTGGTGGTAAAATTCTTAGAATTCTATATGAAGAAAATGATGAATCTGAGGTGGAAATT
ATTCATGTTACATCCCCTATGTTGGAAACAAGGAGGGCAGATTCATTCCGTTATCCTAAAACAGGTACAGCAAATCCTAAAGTCACTTTT
AAGATGTCAGAAATAATGATTGATGCTGAAGGAAGGATCATAGATGTCATAGATAAGGAACTAATTCAACCTTTTGAGATTCTATTTGAA
GGAGTTGAATATATTGCCAGAGCTGGATGGACTCCTGAGGGAAAATATGCTTGGTCCATCCTACTAGATCGCTCCCAGACTCGCCTACAG
ATAGTGTTGATCTCACCTGAATTATTTATCCCAGTAGAAGATGATGTTATGGAAAGGCAGAGACTCATTGAGTCAGTGCCTGATTCTGTG
ACGCCACTAATTATCTATGAAGAAACAACAGACATCTGGATAAATATCCATGACATCTTTCATGTTTTTCCCCAAAGTCACGAAGAGGAA
ATTGAGTTTATTTTTGCCTCTGAATGCAAAACAGGTTTCCGTCATTTATACAAAATTACATCTATTTTAAAGGAAAGCAAATATAAACGA
TCCAGTGGTGGGCTGCCTGCTCCAAGTGATTTCAAGTGTCCTATCAAAGAGGAGATAGCAATTACCAGTGGTGAATGGGAAGTTCTTGGC
CGGCATGGATCTAATATATCATACTTGGGCTACCTGCTGCTGTTTAACTACGTCATCCTGGTGCGGATGGATGGCTGGCCGTCCCTCCAG
GAGTGGATCGTCATCTCCTACATCGTGAGCCTGGCGTTAGAGAAGATACGAGAGATCCTCATGTCAGAACCAGGCAAACTCAGCCAGAAA
ATCAAAGTTTGGCTTCAGGAGTACTGGAACATCACAGATCTCGTGGCCATTTCCACATTCATGATTGGAGCAATTCTTCGCCTACAGAAC
CAGCCCTACATGGGCTATGGCCGGGTGATCTACTGTGTGGATATCATCTTCTGGTACATCCGTGTCCTGGACATCTTTGGTGTCAACAAG
TATCTGGGGCCATACGTGATGATGATTGGAAAGATGATGATCGACATGCTGTACTTTGTGGTCATCATGCTGGTCGTGCTCATGAGTTTC
GGAGTAGCCCGTCAAGCCATTCTGCATCCAGAGGAGAAGCCCTCTTGGAAACTGGCCCGAAACATCTTCTACATGCCCTACTGGATGATC
TATGGAGAGGTGTTTGCAGACCAGATAGACCTCTACGCCATGGAAATTAATCCTCCTTGTGGTGAGAACCTATATGATGAGGAGGGCAAG
CGGCTTCCTCCCTGTATCCCCGGCGCCTGGCTCACTCCAGCACTCATGGCGTGCTATCTACTGGTCGCCAACATCCTGCTGGTGAACCTG
CTGATTGCTGTGTTCAACAATACCTTCTTTGAAGTAAAATCAATATCCAACCAGGTGTGGAAGTTCCAGCGATATCAGCTGATTATGACA
TTTCATGACAGGCCAGTCCTGCCCCCACCGATGATCATTTTAAGCCACATCTACATCATCATTATGCGTCTCAGCGGCCGCTGCAGGAAA
AAGAGAGAAGGGGACCAAGAGGAACGGGATCGTGGATTGAAGCTCTTCCTTAGCGACGAGGAGCTAAAGAGGCTGCATGAGTTCGAGGAG
CAGTGCGTGCAGGAGCACTTCCGGGAGAAGGAGGATGAGCAGCAGTCGTCCAGCGACGAGCGCATCCGGGTCACTTCTGAAAGAGTTGAA
AATATGTCAATGAGGTTGGAAGAAATCAATGAAAGAGAAACTTTTATGAAAACTTCCCTGCAGACTGTTGACCTTCGACTTGCTCAGCTA
GAAGAATTATCTAACAGAATGGTGAATGCTCTTGAAAATCTTGCGGGAATCGACAGGTCTGACCTGATCCAGGCACGGTCCCGGGCTTCT
TCTGAATGTGAGGCAACGTATCTTCTCCGGCAAAGCAGCATCAATAGCGCTGATGGCTACAGCTTGTATCGATATCATTTTAACGGAGAA
GAGTTATTATTTGAGGATACATCTCTCTCCACGTCACCAGGGACAGGAGTCAGGAAAAAAACCTGTTCCTTCCGTATAAAGGAAGAGAAG
GACGTGAAAACGCACCTAGTCCCAGAATGTCAGAACAGTCTTCACCTTTCACTGGGCACAAGCACATCAGCAACCCCAGATGGCAGTCAC
CTTGCAGTAGATGACTTAAAGAACGCTGAAGAGTCAAAATTAGGTCCAGATATTGGGATTTCAAAGGAAGATGATGAAAGACAGACAGAC
TCTAAAAAAGAAGAAACTATTTCCCCAAGTTTAAATAAAACAGATGTGATACATGGACAGGACAAATCAGATGTTCAAAACACTCAGCTA
ACAGTGGAAACGACAAATATAGAAGGCACTATTTCCTATCCCCTGGAAGAAACCAAAATTACACGCTATTTCCCCGATGAAACGATCAAT
GCTTGTAAAACAATGAAGTCCAGAAGCTTCGTCTATTCCCGGGGAAGAAAGCTGGTCGGTGGGGTTAACCAGGATGTAGAGTACAGTTCA
ATCACGGACCAGCAATTGACGACGGAATGGCAATGCCAAGTTCAAAAGATCACGCGCTCTCATAGCACAGATATTCCTTACATTGTGTCG
GAAGCTGCAGTGCAAGCTGAGCATAAAGAGCAGTTTGCAGATATGCAAGATGAACACCATGTCGCTGAAGCAATTCCTCGAATCCCTCGC
TTGTCCCTAACCATTACTGACAGAAATGGGATGGAAAACTTACTGTCTGTGAAGCCAGATCAAACTTTGGGATTCCCATCTCTCAGGTCA
AAAAGTTTACATGGACATCCTAGGAATGTGAAATCCATTCAGGGAAAGTTAGACAGATCTGGACATGCCAGTAGTGTAAGCAGCTTAGTA
ATTGTGTCTGGAATGACAGCAGAAGAAAAAAAGGTTAAGAAAGAGAAAGCTTCCACAGAAACTGAATGCTAGTCTGTTTTGTTTCTTTAA
TTTTTTTTTTTAACAGTCAGAACCACTAATGGGTGTCATCTTGGCCATCTAAACATCATCAATTTCTAAAAACATTTTCCTTAAAAAATT
TTGGAAATTCAGACTTGATTTACAATTTAATGCACTAAAAGTAGTATTTTGTTAGCATATGTTAGTAGGCTTAGTTTTTTCAGTTGCAGT
AGTATCAAATGAAAGTGATGATACTGTAACGAAGATAAATTGGCTAATCAGTATACAAGATTATACAATCTCTTTATTACTGAGGGCCAC
CAAATAGCCTAGGAAGTGCCCTCGAGCACTGAAGTCACCATTAGGTCACTTAAGAAGTAAGCAACTAGCTGGGCACAGTGGCTCATGCCT
GTAATCCTAGCACTTTGGGAGGCCAAGGCAGAAAGATAGCTTGAGTCCAGGAGTTTGAGACCAGCCTGGGCAACATAGTGATACCCCATC
TCTTAAAAAAAAAAAAAAAAGTAAGCAACTGTGTAAGAAAGAGAAACTAAAGAGAAAGCAAACATGAAAAAAGGGAGGGGTGGAAAGAAG
AAAAATAAAATTGTGAGGCACAATAAGTGGGAAGGAGCCACAAATATGTTTTTATGGGGTCTTTGTTTTCTGTTTTAATGTTTTATTTTA
AACTACACAATGGGAAAAAAAGTACACAATTATATCAAACATCATACTCTAATAATTTAGGGTGACCTAGAGTTTTGTTAATGTGCAAAA

>24043_24043_2_DPP8-TRPM1_DPP8_chr15_65766547_ENST00000341861_TRPM1_chr15_31327877_ENST00000397795_length(amino acids)=1296AA_BP=528
MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRND
PDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLF
QAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVAT
FVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVI
DKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIH
DIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNISYLGYLLLFNY
VILVRMDGWPSLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAISTFMIGAILRLQNQPYMGYGRVIYCVDIIF
WYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQIDLYAMEIN
PPCGENLYDEEGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPMIILSHI
YIIIMRLSGRCRKKREGDQEERDRGLKLFLSDEELKRLHEFEEQCVQEHFREKEDEQQSSSDERIRVTSERVENMSMRLEEINERETFMK
TSLQTVDLRLAQLEELSNRMVNALENLAGIDRSDLIQARSRASSECEATYLLRQSSINSADGYSLYRYHFNGEELLFEDTSLSTSPGTGV
RKKTCSFRIKEEKDVKTHLVPECQNSLHLSLGTSTSATPDGSHLAVDDLKNAEESKLGPDIGISKEDDERQTDSKKEETISPSLNKTDVI
HGQDKSDVQNTQLTVETTNIEGTISYPLEETKITRYFPDETINACKTMKSRSFVYSRGRKLVGGVNQDVEYSSITDQQLTTEWQCQVQKI
TRSHSTDIPYIVSEAAVQAEHKEQFADMQDEHHVAEAIPRIPRLSLTITDRNGMENLLSVKPDQTLGFPSLRSKSLHGHPRNVKSIQGKL

--------------------------------------------------------------
>24043_24043_3_DPP8-TRPM1_DPP8_chr15_65766547_ENST00000341861_TRPM1_chr15_31327877_ENST00000542188_length(transcript)=5944nt_BP=3165nt
AGATTCCGAGTCAACCACCGTTCACTGGGCGCCCCTTGAGCTCTGGGCGCTGGCCTCCTGGCTTCCACGTCCGTTATCTTAATTGAGTCT
CGCTGGGGTTGGGAGGCCGGGTATTGTCAGCGCTTACAGATGAGGAAACGGAAGCCCACAGAGGCGAAGGGATTTTCCTTAAGTCCGACT
TGGCAGATGGGCTTCGGCCTCAGATTTTCTGGTTTTTCAGCTGGTGGTCTTTTTTCTCTCCTGCCTCATGCTAGGTCGATTCCCTCCCTG
CTCACTGCCCTCTCCCATTCTGTTCCACCCACTCGCAGCAGGACACTTTCCTTTCCTGCCACACCTGTCTTCTCACACACTTTTCTTCTA
AGACTTGGCATTCCTCCCATCTCTCTTCTCAATATTCTCTGCTATGCCTCTCCTCTTGTTCCTCATTCATAGTTTTTCAAGGTCTTTGCC
CCCTCTGTGCTATTGAATCTCTCAACTAGGTGTGGACCCTAAAGAATGAGATAGCTAGGCTTCAGTGAGGCTTTAGGTGTTTAAGTGGAC
GGCTGTTTGGCCCTTGAGTTAAAAATTAAGGAATTTCACTTGAGTGGATCCAAACTCAAGAGTCCTAAAGCTATTTTCTGAGTCAACATG
CTCTATTTCTGAGTGAGGGGCTTAGTGCTATGAGGTGTCTTGACATCTTAGTCCATTGTTGCTGTGCTGGCATAACCTCGCTGTTTTTCC
TGCACTTGCCACTTAGCTTTTCCCACCCCATCCCTTCATCACCTACTTGGGCTATGGGAGCCCAAAATTAAAACTTATAGAGTAACAGAT
GTAATAGCAGACCTTCCTTTTTTTTTTTTTCCTAAGCCAGAATTTCAACAAGTTTAATGCTTCTTTTTCCAGAAAAGTTACCTATTTAAA
TTATTCTCAGAGTAATGCAGCAAGAAAATGGAATGCACTTAAGATGAATAGAAAATTGTTTATCTCGTGAAAAGTCTTAAGTTATTAAAT
TCAAGTTAATTCCCTTTCTGCAAAAATGGCCTGTAACTCTTACTGGCTATCCTCCTGAGTTAATTCTATCTCCATCCAGCTTGATATGAC
ATTATTATGTAAAAGAGGAACAGGAATAGGCACATAAAAATAAATTTTATTAATCATATGCCGTTTTTGATGATTTGCAATAGTCACTGA
GTAACTTCACATCTGTATGCCTTTTGTAACTTTTTAAAGCCTTTCCATGGTTTTCCTTTGTCTGGACACCAAAGTTTGCTATGTTAGGAT
ATTCTTTTGACTATATTGGGCTACACATCTCTGAAATAAAATAATTCTTGAATTCTGATAACATAAAACGCAGATACAAAATAATGTAGG
CATTATATATTGCCCCAAAAAGTGATATTTTGGTATCAGTTTTAACTACTATTTTGGGGCTTCTCTTTTTGGCCACATATGGTCCATCTT
AATGATCAAAGTCTTATCTTATTTCATTATCCTGGTGAGCAGGCTTTGATGGTGAGGAAAGGAAAGATTCCTGTGAGAAGAGCAGGATGA
GCAGAGGGATTCTATGCTTGAAGTCGAGTCACTTGAAAAAGATCTCTTTGAATGTGGAAGAGATCTGAGCAGATGAAAATAAAATCAGGA
AAATGCAACATGGCAGCAGCAATGGAAACAGAACAGCTGGGTGTTGAGATATTTGAAACTGCGGACTGTGAGGAGAATATTGAATCACAG
GATCGGCCTAAATTGGAGCCTTTTTATGTTGAGCGGTATTCCTGGAGTCAGCTTAAAAAGCTGCTTGCCGATACCAGAAAATATCATGGC
TACATGATGGCTAAGGCACCACATGATTTCATGTTTGTGAAGAGGAATGATCCAGATGGACCTCATTCAGACAGAATCTATTACCTTGCC
ATGTCTGGTGAGAACAGAGAAAATACACTGTTTTATTCTGAAATTCCCAAAACTATCAATAGAGCAGCAGTCTTAATGCTCTCTTGGAAG
CCTCTTTTGGATCTTTTTCAGGCAACACTGGACTATGGAATGTATTCTCGAGAAGAAGAACTATTAAGAGAAAGAAAACGCATTGGAACA
GTCGGAATTGCTTCTTACGATTATCACCAAGGAAGTGGAACATTTCTGTTTCAAGCCGGTAGTGGAATTTATCACGTAAAAGATGGAGGG
CCACAAGGATTTACGCAACAACCTTTAAGGCCCAATCTAGTGGAAACTAGTTGTCCCAACATACGGATGGATCCAAAATTATGCCCTGCT
GATCCAGACTGGATTGCTTTTATACATAGCAACGATATTTGGATATCTAACATCGTAACCAGAGAAGAAAGGAGACTCACTTATGTGCAC
AATGAGCTAGCCAACATGGAAGAAGATGCCAGATCAGCTGGAGTCGCTACCTTTGTTCTCCAAGAAGAATTTGATAGATATTCTGGCTAT
TGGTGGTGTCCAAAAGCTGAAACAACTCCCAGTGGTGGTAAAATTCTTAGAATTCTATATGAAGAAAATGATGAATCTGAGGTGGAAATT
ATTCATGTTACATCCCCTATGTTGGAAACAAGGAGGGCAGATTCATTCCGTTATCCTAAAACAGGTACAGCAAATCCTAAAGTCACTTTT
AAGATGTCAGAAATAATGATTGATGCTGAAGGAAGGATCATAGATGTCATAGATAAGGAACTAATTCAACCTTTTGAGATTCTATTTGAA
GGAGTTGAATATATTGCCAGAGCTGGATGGACTCCTGAGGGAAAATATGCTTGGTCCATCCTACTAGATCGCTCCCAGACTCGCCTACAG
ATAGTGTTGATCTCACCTGAATTATTTATCCCAGTAGAAGATGATGTTATGGAAAGGCAGAGACTCATTGAGTCAGTGCCTGATTCTGTG
ACGCCACTAATTATCTATGAAGAAACAACAGACATCTGGATAAATATCCATGACATCTTTCATGTTTTTCCCCAAAGTCACGAAGAGGAA
ATTGAGTTTATTTTTGCCTCTGAATGCAAAACAGGTTTCCGTCATTTATACAAAATTACATCTATTTTAAAGGAAAGCAAATATAAACGA
TCCAGTGGTGGGCTGCCTGCTCCAAGTGATTTCAAGTGTCCTATCAAAGAGGAGATAGCAATTACCAGTGGTGAATGGGAAGTTCTTGGC
CGGCATGGATCTAATATATCATACTTGGGCTACCTGCTGCTGTTTAACTACGTCATCCTGGTGCGGATGGATGGCTGGCCGTCCCTCCAG
GAGTGGATCGTCATCTCCTACATCGTGAGCCTGGCGTTAGAGAAGATACGAGAGATCCTCATGTCAGAACCAGGCAAACTCAGCCAGAAA
ATCAAAGTTTGGCTTCAGGAGTACTGGAACATCACAGATCTCGTGGCCATTTCCACATTCATGATTGGAGCAATTCTTCGCCTACAGAAC
CAGCCCTACATGGGCTATGGCCGGGTGATCTACTGTGTGGATATCATCTTCTGGTACATCCGTGTCCTGGACATCTTTGGTGTCAACAAG
TATCTGGGGCCATACGTGATGATGATTGGAAAGATGATGATCGACATGCTGTACTTTGTGGTCATCATGCTGGTCGTGCTCATGAGTTTC
GGAGTAGCCCGTCAAGCCATTCTGCATCCAGAGGAGAAGCCCTCTTGGAAACTGGCCCGAAACATCTTCTACATGCCCTACTGGATGATC
TATGGAGAGGTGTTTGCAGACCAGATAGACCTCTACGCCATGGAAATTAATCCTCCTTGTGGTGAGAACCTATATGATGAGGAGGGCAAG
CGGCTTCCTCCCTGTATCCCCGGCGCCTGGCTCACTCCAGCACTCATGGCGTGCTATCTACTGGTCGCCAACATCCTGCTGGTGAACCTG
CTGATTGCTGTGTTCAACAATACCTTCTTTGAAGTAAAATCAATATCCAACCAGGTGTGGAAGTTCCAGCGATATCAGCTGATTATGACA
TTTCATGACAGGCCAGTCCTGCCCCCACCGATGATCATTTTAAGCCACATCTACATCATCATTATGCGTCTCAGCGGCCGCTGCAGGAAA
AAGAGAGAAGGGGACCAAGAGGAACGGGATCGTGGATTGAAGCTCTTCCTTAGCGACGAGGAGCTAAAGAGGCTGCATGAGTTCGAGGAG
CAGTGCGTGCAGGAGCACTTCCGGGAGAAGGAGGATGAGCAGCAGTCGTCCAGCGACGAGCGCATCCGGGTCACTTCTGAAAGAGTTGAA
AATATGTCAATGAGGTTGGAAGAAATCAATGAAAGAGAAACTTTTATGAAAACTTCCCTGCAGACTGTTGACCTTCGACTTGCTCAGCTA
GAAGAATTATCTAACAGAATGGTGAATGCTCTTGAAAATCTTGCGGGAATCGACAGGTCTGACCTGATCCAGGCACGGTCCCGGGCTTCT
TCTGAATGTGAGGCAACGTATCTTCTCCGGCAAAGCAGCATCAATAGCGCTGATGGCTACAGCTTGTATCGATATCATTTTAACGGAGAA
GAGTTATTATTTGAGGATACATCTCTCTCCACGTCACCAGGGACAGGAGTCAGGAAAAAAACCTGTTCCTTCCGTATAAAGGAAGAGAAG
GACGTGAAAACGCACCTAGTCCCAGAATGTCAGAACAGTCTTCACCTTTCACTGGGCACAAGCACATCAGCAACCCCAGATGGCAGTCAC
CTTGCAGTAGATGACTTAAAGAACGCTGAAGAGTCAAAATTAGGTCCAGATATTGGGATTTCAAAGGAAGATGATGAAAGACAGACAGAC
TCTAAAAAAGAAGAAACTATTTCCCCAAGTTTAAATAAAACAGATGTGATACATGGACAGGACAAATCAGATGTTCAAAACACTCAGCTA
ACAGTGGAAACGACAAATATAGAAGGCACTATTTCCTATCCCCTGGAAGAAACCAAAATTACACGCTATTTCCCCGATGAAACGATCAAT
GCTTGTAAAACAATGAAGTCCAGAAGCTTCGTCTATTCCCGGGGAAGAAAGCTGGTCGGTGGGGTTAACCAGGATGTAGAGTACAGTTCA
ATCACGGACCAGCAATTGACGACGGAATGGCAATGCCAAGTTCAAAAGATCACGCGCTCTCATAGCACAGATATTCCTTACATTGTGTCG
GAAGCTGCAGTGCAAGCTGAGCATAAAGAGCAGTTTGCAGATATGCAAGATGAACACCATGTCGCTGAAGCAATTCCTCGAATCCCTCGC
TTGTCCCTAACCATTACTGACAGAAATGGGATGGAAAACTTACTGTCTGTGAAGCCAGATCAAACTTTGGGATTCCCATCTCTCAGGTCA
AAAAGTTTACATGGACATCCTAGGAATGTGAAATCCATTCAGGGAAAGTTAGACAGATCTGGACATGCCAGTAGTGTAAGCAGCTTAGTA
ATTGTGTCTGGAATGACAGCAGAAGAAAAAAAGGTTAAGAAAGAGAAAGCTTCCACAGAAACTGAATGCTAGTCTGTTTTGTTTCTTTAA
TTTTTTTTTTTAACAGTCAGAACCACTAATGGGTGTCATCTTGGCCATCTAAACATCATCAATTTCTAAAAACATTTTCCTTAAAAAATT
TTGGAAATTCAGACTTGATTTACAATTTAATGCACTAAAAGTAGTATTTTGTTAGCATATGTTAGTAGGCTTAGTTTTTTCAGTTGCAGT
AGTATCAAATGAAAGTGATGATACTGTAACGAAGATAAATTGGCTAATCAGTATACAAGATTATACAATCTCTTTATTACTGAGGGCCAC
CAAATAGCCTAGGAAGTGCCCTCGAGCACTGAAGTCACCATTAGGTCACTTAAGAAGTAAGCAACTAGCTGGGCACAGTGGCTCATGCCT
GTAATCCTAGCACTTTGGGAGGCCAAGGCAGAAAGATAGCTTGAGTCCAGGAGTTTGAGACCAGCCTGGGCAACATAGTGATACCCCATC

>24043_24043_3_DPP8-TRPM1_DPP8_chr15_65766547_ENST00000341861_TRPM1_chr15_31327877_ENST00000542188_length(amino acids)=1296AA_BP=528
MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRND
PDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLF
QAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVAT
FVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVI
DKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIH
DIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNISYLGYLLLFNY
VILVRMDGWPSLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAISTFMIGAILRLQNQPYMGYGRVIYCVDIIF
WYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQIDLYAMEIN
PPCGENLYDEEGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPMIILSHI
YIIIMRLSGRCRKKREGDQEERDRGLKLFLSDEELKRLHEFEEQCVQEHFREKEDEQQSSSDERIRVTSERVENMSMRLEEINERETFMK
TSLQTVDLRLAQLEELSNRMVNALENLAGIDRSDLIQARSRASSECEATYLLRQSSINSADGYSLYRYHFNGEELLFEDTSLSTSPGTGV
RKKTCSFRIKEEKDVKTHLVPECQNSLHLSLGTSTSATPDGSHLAVDDLKNAEESKLGPDIGISKEDDERQTDSKKEETISPSLNKTDVI
HGQDKSDVQNTQLTVETTNIEGTISYPLEETKITRYFPDETINACKTMKSRSFVYSRGRKLVGGVNQDVEYSSITDQQLTTEWQCQVQKI
TRSHSTDIPYIVSEAAVQAEHKEQFADMQDEHHVAEAIPRIPRLSLTITDRNGMENLLSVKPDQTLGFPSLRSKSLHGHPRNVKSIQGKL

--------------------------------------------------------------
>24043_24043_4_DPP8-TRPM1_DPP8_chr15_65766547_ENST00000559233_TRPM1_chr15_31327877_ENST00000256552_length(transcript)=4491nt_BP=1696nt
TCCTGGTGAGCAGGCTTTGATGGTGAGGAAAGGAAAGATTCCTGTGAGAAGAGCAGGATGAGCAGAGGGATTCTATGCTTGAAGTCGAGT
CACTTGAAAAAGATCTCTTTGAATGTGGAAGAGATCTGAGCAGATGAAAATAAAATCAGGAAAATGCAACATGGCAGCAGCAATGGAAAC
AGAACAGCTGGGTGTTGAGATATTTGAAACTGCGGACTGTGAGGAGAATATTGAATCACAGGATCGGCCTAAATTGGAGCCTTTTTATGT
TGAGCGGTATTCCTGGAGTCAGCTTAAAAAGCTGCTTGCCGATACCAGAAAATATCATGGCTACATGATGGCTAAGGCACCACATGATTT
CATGTTTGTGAAGAGGAATGATCCAGATGGACCTCATTCAGACAGAATCTATTACCTTGCCATGTCTGGTGAGAACAGAGAAAATACACT
GTTTTATTCTGAAATTCCCAAAACTATCAATAGAGCAGCAGTCTTAATGCTCTCTTGGAAGCCTCTTTTGGATCTTTTTCAGGCAACACT
GGACTATGGAATGTATTCTCGAGAAGAAGAACTATTAAGAGAAAGAAAACGCATTGGAACAGTCGGAATTGCTTCTTACGATTATCACCA
AGGAAGTGGAACATTTCTGTTTCAAGCCGGTAGTGGAATTTATCACGTAAAAGATGGAGGGCCACAAGGATTTACGCAACAACCTTTAAG
GCCCAATCTAGTGGAAACTAGTTGTCCCAACATACGGATGGATCCAAAATTATGCCCTGCTGATCCAGACTGGATTGCTTTTATACATAG
CAACGATATTTGGATATCTAACATCGTAACCAGAGAAGAAAGGAGACTCACTTATGTGCACAATGAGCTAGCCAACATGGAAGAAGATGC
CAGATCAGCTGGAGTCGCTACCTTTGTTCTCCAAGAAGAATTTGATAGATATTCTGGCTATTGGTGGTGTCCAAAAGCTGAAACAACTCC
CAGTGGTGGTAAAATTCTTAGAATTCTATATGAAGAAAATGATGAATCTGAGGTGGAAATTATTCATGTTACATCCCCTATGTTGGAAAC
AAGGAGGGCAGATTCATTCCGTTATCCTAAAACAGGTACAGCAAATCCTAAAGTCACTTTTAAGATGTCAGAAATAATGATTGATGCTGA
AGGAAGGATCATAGATGTCATAGATAAGGAACTAATTCAACCTTTTGAGATTCTATTTGAAGGAGTTGAATATATTGCCAGAGCTGGATG
GACTCCTGAGGGAAAATATGCTTGGTCCATCCTACTAGATCGCTCCCAGACTCGCCTACAGATAGTGTTGATCTCACCTGAATTATTTAT
CCCAGTAGAAGATGATGTTATGGAAAGGCAGAGACTCATTGAGTCAGTGCCTGATTCTGTGACGCCACTAATTATCTATGAAGAAACAAC
AGACATCTGGATAAATATCCATGACATCTTTCATGTTTTTCCCCAAAGTCACGAAGAGGAAATTGAGTTTATTTTTGCCTCTGAATGCAA
AACAGGTTTCCGTCATTTATACAAAATTACATCTATTTTAAAGGAAAGCAAATATAAACGATCCAGTGGTGGGCTGCCTGCTCCAAGTGA
TTTCAAGTGTCCTATCAAAGAGGAGATAGCAATTACCAGTGGTGAATGGGAAGTTCTTGGCCGGCATGGATCTAATATATCATACTTGGG
CTACCTGCTGCTGTTTAACTACGTCATCCTGGTGCGGATGGATGGCTGGCCGTCCCTCCAGGAGTGGATCGTCATCTCCTACATCGTGAG
CCTGGCGTTAGAGAAGATACGAGAGATCCTCATGTCAGAACCAGGCAAACTCAGCCAGAAAATCAAAGTTTGGCTTCAGGAGTACTGGAA
CATCACAGATCTCGTGGCCATTTCCACATTCATGATTGGAGCAATTCTTCGCCTACAGAACCAGCCCTACATGGGCTATGGCCGGGTGAT
CTACTGTGTGGATATCATCTTCTGGTACATCCGTGTCCTGGACATCTTTGGTGTCAACAAGTATCTGGGGCCATACGTGATGATGATTGG
AAAGATGATGATCGACATGCTGTACTTTGTGGTCATCATGCTGGTCGTGCTCATGAGTTTCGGAGTAGCCCGTCAAGCCATTCTGCATCC
AGAGGAGAAGCCCTCTTGGAAACTGGCCCGAAACATCTTCTACATGCCCTACTGGATGATCTATGGAGAGGTGTTTGCAGACCAGATAGA
CCTCTACGCCATGGAAATTAATCCTCCTTGTGGTGAGAACCTATATGATGAGGAGGGCAAGCGGCTTCCTCCCTGTATCCCCGGCGCCTG
GCTCACTCCAGCACTCATGGCGTGCTATCTACTGGTCGCCAACATCCTGCTGGTGAACCTGCTGATTGCTGTGTTCAACAATACCTTCTT
TGAAGTAAAATCAATATCCAACCAGGTGTGGAAGTTCCAGCGATATCAGCTGATTATGACATTTCATGACAGGCCAGTCCTGCCCCCACC
GATGATCATTTTAAGCCACATCTACATCATCATTATGCGTCTCAGCGGCCGCTGCAGGAAAAAGAGAGAAGGGGACCAAGAGGAACGGGA
TCGTGGATTGAAGCTCTTCCTTAGCGACGAGGAGCTAAAGAGGCTGCATGAGTTCGAGGAGCAGTGCGTGCAGGAGCACTTCCGGGAGAA
GGAGGATGAGCAGCAGTCGTCCAGCGACGAGCGCATCCGGGTCACTTCTGAAAGAGTTGAAAATATGTCAATGAGGTTGGAAGAAATCAA
TGAAAGAGAAACTTTTATGAAAACTTCCCTGCAGACTGTTGACCTTCGACTTGCTCAGCTAGAAGAATTATCTAACAGAATGGTGAATGC
TCTTGAAAATCTTGCGGGAATCGACAGGTCTGACCTGATCCAGGCACGGTCCCGGGCTTCTTCTGAATGTGAGGCAACGTATCTTCTCCG
GCAAAGCAGCATCAATAGCGCTGATGGCTACAGCTTGTATCGATATCATTTTAACGGAGAAGAGTTATTATTTGAGGATACATCTCTCTC
CACGTCACCAGGGACAGGAGTCAGGAAAAAAACCTGTTCCTTCCGTATAAAGGAAGAGAAGGACGTGAAAACGCACCTAGTCCCAGAATG
TCAGAACAGTCTTCACCTTTCACTGGGCACAAGCACATCAGCAACCCCAGATGGCAGTCACCTTGCAGTAGATGACTTAAAGAACGCTGA
AGAGTCAAAATTAGGTCCAGATATTGGGATTTCAAAGGAAGATGATGAAAGACAGACAGACTCTAAAAAAGAAGAAACTATTTCCCCAAG
TTTAAATAAAACAGATGTGATACATGGACAGGACAAATCAGATGTTCAAAACACTCAGCTAACAGTGGAAACGACAAATATAGAAGGCAC
TATTTCCTATCCCCTGGAAGAAACCAAAATTACACGCTATTTCCCCGATGAAACGATCAATGCTTGTAAAACAATGAAGTCCAGAAGCTT
CGTCTATTCCCGGGGAAGAAAGCTGGTCGGTGGGGTTAACCAGGATGTAGAGTACAGTTCAATCACGGACCAGCAATTGACGACGGAATG
GCAATGCCAAGTTCAAAAGATCACGCGCTCTCATAGCACAGATATTCCTTACATTGTGTCGGAAGCTGCAGTGCAAGCTGAGCATAAAGA
GCAGTTTGCAGATATGCAAGATGAACACCATGTCGCTGAAGCAATTCCTCGAATCCCTCGCTTGTCCCTAACCATTACTGACAGAAATGG
GATGGAAAACTTACTGTCTGTGAAGCCAGATCAAACTTTGGGATTCCCATCTCTCAGGTCAAAAAGTTTACATGGACATCCTAGGAATGT
GAAATCCATTCAGGGAAAGTTAGACAGATCTGGACATGCCAGTAGTGTAAGCAGCTTAGTAATTGTGTCTGGAATGACAGCAGAAGAAAA
AAAGGTTAAGAAAGAGAAAGCTTCCACAGAAACTGAATGCTAGTCTGTTTTGTTTCTTTAATTTTTTTTTTTAACAGTCAGAACCACTAA
TGGGTGTCATCTTGGCCATCTAAACATCATCAATTTCTAAAAACATTTTCCTTAAAAAATTTTGGAAATTCAGACTTGATTTACAATTTA
ATGCACTAAAAGTAGTATTTTGTTAGCATATGTTAGTAGGCTTAGTTTTTTCAGTTGCAGTAGTATCAAATGAAAGTGATGATACTGTAA
CGAAGATAAATTGGCTAATCAGTATACAAGATTATACAATCTCTTTATTACTGAGGGCCACCAAATAGCCTAGGAAGTGCCCTCGAGCAC
TGAAGTCACCATTAGGTCACTTAAGAAGTAAGCAACTAGCTGGGCACAGTGGCTCATGCCTGTAATCCTAGCACTTTGGGAGGCCAAGGC

>24043_24043_4_DPP8-TRPM1_DPP8_chr15_65766547_ENST00000559233_TRPM1_chr15_31327877_ENST00000256552_length(amino acids)=1296AA_BP=528
MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRND
PDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLF
QAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVAT
FVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVI
DKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIH
DIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNISYLGYLLLFNY
VILVRMDGWPSLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAISTFMIGAILRLQNQPYMGYGRVIYCVDIIF
WYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQIDLYAMEIN
PPCGENLYDEEGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPMIILSHI
YIIIMRLSGRCRKKREGDQEERDRGLKLFLSDEELKRLHEFEEQCVQEHFREKEDEQQSSSDERIRVTSERVENMSMRLEEINERETFMK
TSLQTVDLRLAQLEELSNRMVNALENLAGIDRSDLIQARSRASSECEATYLLRQSSINSADGYSLYRYHFNGEELLFEDTSLSTSPGTGV
RKKTCSFRIKEEKDVKTHLVPECQNSLHLSLGTSTSATPDGSHLAVDDLKNAEESKLGPDIGISKEDDERQTDSKKEETISPSLNKTDVI
HGQDKSDVQNTQLTVETTNIEGTISYPLEETKITRYFPDETINACKTMKSRSFVYSRGRKLVGGVNQDVEYSSITDQQLTTEWQCQVQKI
TRSHSTDIPYIVSEAAVQAEHKEQFADMQDEHHVAEAIPRIPRLSLTITDRNGMENLLSVKPDQTLGFPSLRSKSLHGHPRNVKSIQGKL

--------------------------------------------------------------
>24043_24043_5_DPP8-TRPM1_DPP8_chr15_65766547_ENST00000559233_TRPM1_chr15_31327877_ENST00000397795_length(transcript)=4764nt_BP=1696nt
TCCTGGTGAGCAGGCTTTGATGGTGAGGAAAGGAAAGATTCCTGTGAGAAGAGCAGGATGAGCAGAGGGATTCTATGCTTGAAGTCGAGT
CACTTGAAAAAGATCTCTTTGAATGTGGAAGAGATCTGAGCAGATGAAAATAAAATCAGGAAAATGCAACATGGCAGCAGCAATGGAAAC
AGAACAGCTGGGTGTTGAGATATTTGAAACTGCGGACTGTGAGGAGAATATTGAATCACAGGATCGGCCTAAATTGGAGCCTTTTTATGT
TGAGCGGTATTCCTGGAGTCAGCTTAAAAAGCTGCTTGCCGATACCAGAAAATATCATGGCTACATGATGGCTAAGGCACCACATGATTT
CATGTTTGTGAAGAGGAATGATCCAGATGGACCTCATTCAGACAGAATCTATTACCTTGCCATGTCTGGTGAGAACAGAGAAAATACACT
GTTTTATTCTGAAATTCCCAAAACTATCAATAGAGCAGCAGTCTTAATGCTCTCTTGGAAGCCTCTTTTGGATCTTTTTCAGGCAACACT
GGACTATGGAATGTATTCTCGAGAAGAAGAACTATTAAGAGAAAGAAAACGCATTGGAACAGTCGGAATTGCTTCTTACGATTATCACCA
AGGAAGTGGAACATTTCTGTTTCAAGCCGGTAGTGGAATTTATCACGTAAAAGATGGAGGGCCACAAGGATTTACGCAACAACCTTTAAG
GCCCAATCTAGTGGAAACTAGTTGTCCCAACATACGGATGGATCCAAAATTATGCCCTGCTGATCCAGACTGGATTGCTTTTATACATAG
CAACGATATTTGGATATCTAACATCGTAACCAGAGAAGAAAGGAGACTCACTTATGTGCACAATGAGCTAGCCAACATGGAAGAAGATGC
CAGATCAGCTGGAGTCGCTACCTTTGTTCTCCAAGAAGAATTTGATAGATATTCTGGCTATTGGTGGTGTCCAAAAGCTGAAACAACTCC
CAGTGGTGGTAAAATTCTTAGAATTCTATATGAAGAAAATGATGAATCTGAGGTGGAAATTATTCATGTTACATCCCCTATGTTGGAAAC
AAGGAGGGCAGATTCATTCCGTTATCCTAAAACAGGTACAGCAAATCCTAAAGTCACTTTTAAGATGTCAGAAATAATGATTGATGCTGA
AGGAAGGATCATAGATGTCATAGATAAGGAACTAATTCAACCTTTTGAGATTCTATTTGAAGGAGTTGAATATATTGCCAGAGCTGGATG
GACTCCTGAGGGAAAATATGCTTGGTCCATCCTACTAGATCGCTCCCAGACTCGCCTACAGATAGTGTTGATCTCACCTGAATTATTTAT
CCCAGTAGAAGATGATGTTATGGAAAGGCAGAGACTCATTGAGTCAGTGCCTGATTCTGTGACGCCACTAATTATCTATGAAGAAACAAC
AGACATCTGGATAAATATCCATGACATCTTTCATGTTTTTCCCCAAAGTCACGAAGAGGAAATTGAGTTTATTTTTGCCTCTGAATGCAA
AACAGGTTTCCGTCATTTATACAAAATTACATCTATTTTAAAGGAAAGCAAATATAAACGATCCAGTGGTGGGCTGCCTGCTCCAAGTGA
TTTCAAGTGTCCTATCAAAGAGGAGATAGCAATTACCAGTGGTGAATGGGAAGTTCTTGGCCGGCATGGATCTAATATATCATACTTGGG
CTACCTGCTGCTGTTTAACTACGTCATCCTGGTGCGGATGGATGGCTGGCCGTCCCTCCAGGAGTGGATCGTCATCTCCTACATCGTGAG
CCTGGCGTTAGAGAAGATACGAGAGATCCTCATGTCAGAACCAGGCAAACTCAGCCAGAAAATCAAAGTTTGGCTTCAGGAGTACTGGAA
CATCACAGATCTCGTGGCCATTTCCACATTCATGATTGGAGCAATTCTTCGCCTACAGAACCAGCCCTACATGGGCTATGGCCGGGTGAT
CTACTGTGTGGATATCATCTTCTGGTACATCCGTGTCCTGGACATCTTTGGTGTCAACAAGTATCTGGGGCCATACGTGATGATGATTGG
AAAGATGATGATCGACATGCTGTACTTTGTGGTCATCATGCTGGTCGTGCTCATGAGTTTCGGAGTAGCCCGTCAAGCCATTCTGCATCC
AGAGGAGAAGCCCTCTTGGAAACTGGCCCGAAACATCTTCTACATGCCCTACTGGATGATCTATGGAGAGGTGTTTGCAGACCAGATAGA
CCTCTACGCCATGGAAATTAATCCTCCTTGTGGTGAGAACCTATATGATGAGGAGGGCAAGCGGCTTCCTCCCTGTATCCCCGGCGCCTG
GCTCACTCCAGCACTCATGGCGTGCTATCTACTGGTCGCCAACATCCTGCTGGTGAACCTGCTGATTGCTGTGTTCAACAATACCTTCTT
TGAAGTAAAATCAATATCCAACCAGGTGTGGAAGTTCCAGCGATATCAGCTGATTATGACATTTCATGACAGGCCAGTCCTGCCCCCACC
GATGATCATTTTAAGCCACATCTACATCATCATTATGCGTCTCAGCGGCCGCTGCAGGAAAAAGAGAGAAGGGGACCAAGAGGAACGGGA
TCGTGGATTGAAGCTCTTCCTTAGCGACGAGGAGCTAAAGAGGCTGCATGAGTTCGAGGAGCAGTGCGTGCAGGAGCACTTCCGGGAGAA
GGAGGATGAGCAGCAGTCGTCCAGCGACGAGCGCATCCGGGTCACTTCTGAAAGAGTTGAAAATATGTCAATGAGGTTGGAAGAAATCAA
TGAAAGAGAAACTTTTATGAAAACTTCCCTGCAGACTGTTGACCTTCGACTTGCTCAGCTAGAAGAATTATCTAACAGAATGGTGAATGC
TCTTGAAAATCTTGCGGGAATCGACAGGTCTGACCTGATCCAGGCACGGTCCCGGGCTTCTTCTGAATGTGAGGCAACGTATCTTCTCCG
GCAAAGCAGCATCAATAGCGCTGATGGCTACAGCTTGTATCGATATCATTTTAACGGAGAAGAGTTATTATTTGAGGATACATCTCTCTC
CACGTCACCAGGGACAGGAGTCAGGAAAAAAACCTGTTCCTTCCGTATAAAGGAAGAGAAGGACGTGAAAACGCACCTAGTCCCAGAATG
TCAGAACAGTCTTCACCTTTCACTGGGCACAAGCACATCAGCAACCCCAGATGGCAGTCACCTTGCAGTAGATGACTTAAAGAACGCTGA
AGAGTCAAAATTAGGTCCAGATATTGGGATTTCAAAGGAAGATGATGAAAGACAGACAGACTCTAAAAAAGAAGAAACTATTTCCCCAAG
TTTAAATAAAACAGATGTGATACATGGACAGGACAAATCAGATGTTCAAAACACTCAGCTAACAGTGGAAACGACAAATATAGAAGGCAC
TATTTCCTATCCCCTGGAAGAAACCAAAATTACACGCTATTTCCCCGATGAAACGATCAATGCTTGTAAAACAATGAAGTCCAGAAGCTT
CGTCTATTCCCGGGGAAGAAAGCTGGTCGGTGGGGTTAACCAGGATGTAGAGTACAGTTCAATCACGGACCAGCAATTGACGACGGAATG
GCAATGCCAAGTTCAAAAGATCACGCGCTCTCATAGCACAGATATTCCTTACATTGTGTCGGAAGCTGCAGTGCAAGCTGAGCATAAAGA
GCAGTTTGCAGATATGCAAGATGAACACCATGTCGCTGAAGCAATTCCTCGAATCCCTCGCTTGTCCCTAACCATTACTGACAGAAATGG
GATGGAAAACTTACTGTCTGTGAAGCCAGATCAAACTTTGGGATTCCCATCTCTCAGGTCAAAAAGTTTACATGGACATCCTAGGAATGT
GAAATCCATTCAGGGAAAGTTAGACAGATCTGGACATGCCAGTAGTGTAAGCAGCTTAGTAATTGTGTCTGGAATGACAGCAGAAGAAAA
AAAGGTTAAGAAAGAGAAAGCTTCCACAGAAACTGAATGCTAGTCTGTTTTGTTTCTTTAATTTTTTTTTTTAACAGTCAGAACCACTAA
TGGGTGTCATCTTGGCCATCTAAACATCATCAATTTCTAAAAACATTTTCCTTAAAAAATTTTGGAAATTCAGACTTGATTTACAATTTA
ATGCACTAAAAGTAGTATTTTGTTAGCATATGTTAGTAGGCTTAGTTTTTTCAGTTGCAGTAGTATCAAATGAAAGTGATGATACTGTAA
CGAAGATAAATTGGCTAATCAGTATACAAGATTATACAATCTCTTTATTACTGAGGGCCACCAAATAGCCTAGGAAGTGCCCTCGAGCAC
TGAAGTCACCATTAGGTCACTTAAGAAGTAAGCAACTAGCTGGGCACAGTGGCTCATGCCTGTAATCCTAGCACTTTGGGAGGCCAAGGC
AGAAAGATAGCTTGAGTCCAGGAGTTTGAGACCAGCCTGGGCAACATAGTGATACCCCATCTCTTAAAAAAAAAAAAAAAAGTAAGCAAC
TGTGTAAGAAAGAGAAACTAAAGAGAAAGCAAACATGAAAAAAGGGAGGGGTGGAAAGAAGAAAAATAAAATTGTGAGGCACAATAAGTG
GGAAGGAGCCACAAATATGTTTTTATGGGGTCTTTGTTTTCTGTTTTAATGTTTTATTTTAAACTACACAATGGGAAAAAAAGTACACAA

>24043_24043_5_DPP8-TRPM1_DPP8_chr15_65766547_ENST00000559233_TRPM1_chr15_31327877_ENST00000397795_length(amino acids)=1296AA_BP=528
MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRND
PDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLF
QAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVAT
FVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVI
DKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIH
DIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNISYLGYLLLFNY
VILVRMDGWPSLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAISTFMIGAILRLQNQPYMGYGRVIYCVDIIF
WYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQIDLYAMEIN
PPCGENLYDEEGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPMIILSHI
YIIIMRLSGRCRKKREGDQEERDRGLKLFLSDEELKRLHEFEEQCVQEHFREKEDEQQSSSDERIRVTSERVENMSMRLEEINERETFMK
TSLQTVDLRLAQLEELSNRMVNALENLAGIDRSDLIQARSRASSECEATYLLRQSSINSADGYSLYRYHFNGEELLFEDTSLSTSPGTGV
RKKTCSFRIKEEKDVKTHLVPECQNSLHLSLGTSTSATPDGSHLAVDDLKNAEESKLGPDIGISKEDDERQTDSKKEETISPSLNKTDVI
HGQDKSDVQNTQLTVETTNIEGTISYPLEETKITRYFPDETINACKTMKSRSFVYSRGRKLVGGVNQDVEYSSITDQQLTTEWQCQVQKI
TRSHSTDIPYIVSEAAVQAEHKEQFADMQDEHHVAEAIPRIPRLSLTITDRNGMENLLSVKPDQTLGFPSLRSKSLHGHPRNVKSIQGKL

--------------------------------------------------------------
>24043_24043_6_DPP8-TRPM1_DPP8_chr15_65766547_ENST00000559233_TRPM1_chr15_31327877_ENST00000542188_length(transcript)=4475nt_BP=1696nt
TCCTGGTGAGCAGGCTTTGATGGTGAGGAAAGGAAAGATTCCTGTGAGAAGAGCAGGATGAGCAGAGGGATTCTATGCTTGAAGTCGAGT
CACTTGAAAAAGATCTCTTTGAATGTGGAAGAGATCTGAGCAGATGAAAATAAAATCAGGAAAATGCAACATGGCAGCAGCAATGGAAAC
AGAACAGCTGGGTGTTGAGATATTTGAAACTGCGGACTGTGAGGAGAATATTGAATCACAGGATCGGCCTAAATTGGAGCCTTTTTATGT
TGAGCGGTATTCCTGGAGTCAGCTTAAAAAGCTGCTTGCCGATACCAGAAAATATCATGGCTACATGATGGCTAAGGCACCACATGATTT
CATGTTTGTGAAGAGGAATGATCCAGATGGACCTCATTCAGACAGAATCTATTACCTTGCCATGTCTGGTGAGAACAGAGAAAATACACT
GTTTTATTCTGAAATTCCCAAAACTATCAATAGAGCAGCAGTCTTAATGCTCTCTTGGAAGCCTCTTTTGGATCTTTTTCAGGCAACACT
GGACTATGGAATGTATTCTCGAGAAGAAGAACTATTAAGAGAAAGAAAACGCATTGGAACAGTCGGAATTGCTTCTTACGATTATCACCA
AGGAAGTGGAACATTTCTGTTTCAAGCCGGTAGTGGAATTTATCACGTAAAAGATGGAGGGCCACAAGGATTTACGCAACAACCTTTAAG
GCCCAATCTAGTGGAAACTAGTTGTCCCAACATACGGATGGATCCAAAATTATGCCCTGCTGATCCAGACTGGATTGCTTTTATACATAG
CAACGATATTTGGATATCTAACATCGTAACCAGAGAAGAAAGGAGACTCACTTATGTGCACAATGAGCTAGCCAACATGGAAGAAGATGC
CAGATCAGCTGGAGTCGCTACCTTTGTTCTCCAAGAAGAATTTGATAGATATTCTGGCTATTGGTGGTGTCCAAAAGCTGAAACAACTCC
CAGTGGTGGTAAAATTCTTAGAATTCTATATGAAGAAAATGATGAATCTGAGGTGGAAATTATTCATGTTACATCCCCTATGTTGGAAAC
AAGGAGGGCAGATTCATTCCGTTATCCTAAAACAGGTACAGCAAATCCTAAAGTCACTTTTAAGATGTCAGAAATAATGATTGATGCTGA
AGGAAGGATCATAGATGTCATAGATAAGGAACTAATTCAACCTTTTGAGATTCTATTTGAAGGAGTTGAATATATTGCCAGAGCTGGATG
GACTCCTGAGGGAAAATATGCTTGGTCCATCCTACTAGATCGCTCCCAGACTCGCCTACAGATAGTGTTGATCTCACCTGAATTATTTAT
CCCAGTAGAAGATGATGTTATGGAAAGGCAGAGACTCATTGAGTCAGTGCCTGATTCTGTGACGCCACTAATTATCTATGAAGAAACAAC
AGACATCTGGATAAATATCCATGACATCTTTCATGTTTTTCCCCAAAGTCACGAAGAGGAAATTGAGTTTATTTTTGCCTCTGAATGCAA
AACAGGTTTCCGTCATTTATACAAAATTACATCTATTTTAAAGGAAAGCAAATATAAACGATCCAGTGGTGGGCTGCCTGCTCCAAGTGA
TTTCAAGTGTCCTATCAAAGAGGAGATAGCAATTACCAGTGGTGAATGGGAAGTTCTTGGCCGGCATGGATCTAATATATCATACTTGGG
CTACCTGCTGCTGTTTAACTACGTCATCCTGGTGCGGATGGATGGCTGGCCGTCCCTCCAGGAGTGGATCGTCATCTCCTACATCGTGAG
CCTGGCGTTAGAGAAGATACGAGAGATCCTCATGTCAGAACCAGGCAAACTCAGCCAGAAAATCAAAGTTTGGCTTCAGGAGTACTGGAA
CATCACAGATCTCGTGGCCATTTCCACATTCATGATTGGAGCAATTCTTCGCCTACAGAACCAGCCCTACATGGGCTATGGCCGGGTGAT
CTACTGTGTGGATATCATCTTCTGGTACATCCGTGTCCTGGACATCTTTGGTGTCAACAAGTATCTGGGGCCATACGTGATGATGATTGG
AAAGATGATGATCGACATGCTGTACTTTGTGGTCATCATGCTGGTCGTGCTCATGAGTTTCGGAGTAGCCCGTCAAGCCATTCTGCATCC
AGAGGAGAAGCCCTCTTGGAAACTGGCCCGAAACATCTTCTACATGCCCTACTGGATGATCTATGGAGAGGTGTTTGCAGACCAGATAGA
CCTCTACGCCATGGAAATTAATCCTCCTTGTGGTGAGAACCTATATGATGAGGAGGGCAAGCGGCTTCCTCCCTGTATCCCCGGCGCCTG
GCTCACTCCAGCACTCATGGCGTGCTATCTACTGGTCGCCAACATCCTGCTGGTGAACCTGCTGATTGCTGTGTTCAACAATACCTTCTT
TGAAGTAAAATCAATATCCAACCAGGTGTGGAAGTTCCAGCGATATCAGCTGATTATGACATTTCATGACAGGCCAGTCCTGCCCCCACC
GATGATCATTTTAAGCCACATCTACATCATCATTATGCGTCTCAGCGGCCGCTGCAGGAAAAAGAGAGAAGGGGACCAAGAGGAACGGGA
TCGTGGATTGAAGCTCTTCCTTAGCGACGAGGAGCTAAAGAGGCTGCATGAGTTCGAGGAGCAGTGCGTGCAGGAGCACTTCCGGGAGAA
GGAGGATGAGCAGCAGTCGTCCAGCGACGAGCGCATCCGGGTCACTTCTGAAAGAGTTGAAAATATGTCAATGAGGTTGGAAGAAATCAA
TGAAAGAGAAACTTTTATGAAAACTTCCCTGCAGACTGTTGACCTTCGACTTGCTCAGCTAGAAGAATTATCTAACAGAATGGTGAATGC
TCTTGAAAATCTTGCGGGAATCGACAGGTCTGACCTGATCCAGGCACGGTCCCGGGCTTCTTCTGAATGTGAGGCAACGTATCTTCTCCG
GCAAAGCAGCATCAATAGCGCTGATGGCTACAGCTTGTATCGATATCATTTTAACGGAGAAGAGTTATTATTTGAGGATACATCTCTCTC
CACGTCACCAGGGACAGGAGTCAGGAAAAAAACCTGTTCCTTCCGTATAAAGGAAGAGAAGGACGTGAAAACGCACCTAGTCCCAGAATG
TCAGAACAGTCTTCACCTTTCACTGGGCACAAGCACATCAGCAACCCCAGATGGCAGTCACCTTGCAGTAGATGACTTAAAGAACGCTGA
AGAGTCAAAATTAGGTCCAGATATTGGGATTTCAAAGGAAGATGATGAAAGACAGACAGACTCTAAAAAAGAAGAAACTATTTCCCCAAG
TTTAAATAAAACAGATGTGATACATGGACAGGACAAATCAGATGTTCAAAACACTCAGCTAACAGTGGAAACGACAAATATAGAAGGCAC
TATTTCCTATCCCCTGGAAGAAACCAAAATTACACGCTATTTCCCCGATGAAACGATCAATGCTTGTAAAACAATGAAGTCCAGAAGCTT
CGTCTATTCCCGGGGAAGAAAGCTGGTCGGTGGGGTTAACCAGGATGTAGAGTACAGTTCAATCACGGACCAGCAATTGACGACGGAATG
GCAATGCCAAGTTCAAAAGATCACGCGCTCTCATAGCACAGATATTCCTTACATTGTGTCGGAAGCTGCAGTGCAAGCTGAGCATAAAGA
GCAGTTTGCAGATATGCAAGATGAACACCATGTCGCTGAAGCAATTCCTCGAATCCCTCGCTTGTCCCTAACCATTACTGACAGAAATGG
GATGGAAAACTTACTGTCTGTGAAGCCAGATCAAACTTTGGGATTCCCATCTCTCAGGTCAAAAAGTTTACATGGACATCCTAGGAATGT
GAAATCCATTCAGGGAAAGTTAGACAGATCTGGACATGCCAGTAGTGTAAGCAGCTTAGTAATTGTGTCTGGAATGACAGCAGAAGAAAA
AAAGGTTAAGAAAGAGAAAGCTTCCACAGAAACTGAATGCTAGTCTGTTTTGTTTCTTTAATTTTTTTTTTTAACAGTCAGAACCACTAA
TGGGTGTCATCTTGGCCATCTAAACATCATCAATTTCTAAAAACATTTTCCTTAAAAAATTTTGGAAATTCAGACTTGATTTACAATTTA
ATGCACTAAAAGTAGTATTTTGTTAGCATATGTTAGTAGGCTTAGTTTTTTCAGTTGCAGTAGTATCAAATGAAAGTGATGATACTGTAA
CGAAGATAAATTGGCTAATCAGTATACAAGATTATACAATCTCTTTATTACTGAGGGCCACCAAATAGCCTAGGAAGTGCCCTCGAGCAC
TGAAGTCACCATTAGGTCACTTAAGAAGTAAGCAACTAGCTGGGCACAGTGGCTCATGCCTGTAATCCTAGCACTTTGGGAGGCCAAGGC

>24043_24043_6_DPP8-TRPM1_DPP8_chr15_65766547_ENST00000559233_TRPM1_chr15_31327877_ENST00000542188_length(amino acids)=1296AA_BP=528
MWKRSEQMKIKSGKCNMAAAMETEQLGVEIFETADCEENIESQDRPKLEPFYVERYSWSQLKKLLADTRKYHGYMMAKAPHDFMFVKRND
PDGPHSDRIYYLAMSGENRENTLFYSEIPKTINRAAVLMLSWKPLLDLFQATLDYGMYSREEELLRERKRIGTVGIASYDYHQGSGTFLF
QAGSGIYHVKDGGPQGFTQQPLRPNLVETSCPNIRMDPKLCPADPDWIAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVAT
FVLQEEFDRYSGYWWCPKAETTPSGGKILRILYEENDESEVEIIHVTSPMLETRRADSFRYPKTGTANPKVTFKMSEIMIDAEGRIIDVI
DKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQIVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIH
DIFHVFPQSHEEEIEFIFASECKTGFRHLYKITSILKESKYKRSSGGLPAPSDFKCPIKEEIAITSGEWEVLGRHGSNISYLGYLLLFNY
VILVRMDGWPSLQEWIVISYIVSLALEKIREILMSEPGKLSQKIKVWLQEYWNITDLVAISTFMIGAILRLQNQPYMGYGRVIYCVDIIF
WYIRVLDIFGVNKYLGPYVMMIGKMMIDMLYFVVIMLVVLMSFGVARQAILHPEEKPSWKLARNIFYMPYWMIYGEVFADQIDLYAMEIN
PPCGENLYDEEGKRLPPCIPGAWLTPALMACYLLVANILLVNLLIAVFNNTFFEVKSISNQVWKFQRYQLIMTFHDRPVLPPPMIILSHI
YIIIMRLSGRCRKKREGDQEERDRGLKLFLSDEELKRLHEFEEQCVQEHFREKEDEQQSSSDERIRVTSERVENMSMRLEEINERETFMK
TSLQTVDLRLAQLEELSNRMVNALENLAGIDRSDLIQARSRASSECEATYLLRQSSINSADGYSLYRYHFNGEELLFEDTSLSTSPGTGV
RKKTCSFRIKEEKDVKTHLVPECQNSLHLSLGTSTSATPDGSHLAVDDLKNAEESKLGPDIGISKEDDERQTDSKKEETISPSLNKTDVI
HGQDKSDVQNTQLTVETTNIEGTISYPLEETKITRYFPDETINACKTMKSRSFVYSRGRKLVGGVNQDVEYSSITDQQLTTEWQCQVQKI
TRSHSTDIPYIVSEAAVQAEHKEQFADMQDEHHVAEAIPRIPRLSLTITDRNGMENLLSVKPDQTLGFPSLRSKSLHGHPRNVKSIQGKL

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Fusion Gene PPI Analysis for DPP8-TRPM1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DPP8-TRPM1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DPP8-TRPM1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource