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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DTNBP1-PITPNC1 (FusionGDB2 ID:24383)

Fusion Gene Summary for DTNBP1-PITPNC1

check button Fusion gene summary
Fusion gene informationFusion gene name: DTNBP1-PITPNC1
Fusion gene ID: 24383
HgeneTgene
Gene symbol

DTNBP1

PITPNC1

Gene ID

84062

26207

Gene namedystrobrevin binding protein 1phosphatidylinositol transfer protein cytoplasmic 1
SynonymsBLOC1S8|DBND|HPS7|My031|SDYM-RDGB-beta|MRDGBbeta|RDGB-BETA|RDGBB|RDGBB1
Cytomap

6p22.3

17q24.2

Type of geneprotein-codingprotein-coding
DescriptiondysbindinBLOC-1 subunit 8Hermansky-Pudlak syndrome 7 proteinbiogenesis of lysosomal organelles complex-1, subunit 8biogenesis of lysosome-related organelles complex 1 subunit 8dysbindin-1cytoplasmic phosphatidylinositol transfer protein 1M-rdgB betamammalian rdgB homolog betaretinal degeneration B beta 1retinal degeneration B homolog beta
Modification date2020031320200313
UniProtAcc

Q96EV8

.
Ensembl transtripts involved in fusion geneENST00000338950, ENST00000344537, 
ENST00000355917, ENST00000462989, 
ENST00000299954, ENST00000335257, 
ENST00000580974, ENST00000581322, 
Fusion gene scores* DoF score6 X 4 X 4=9631 X 22 X 12=8184
# samples 652
** MAII scorelog2(6/96*10)=-0.678071905112638
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(52/8184*10)=-3.97622261671687
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: DTNBP1 [Title/Abstract] AND PITPNC1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointDTNBP1(15663045)-PITPNC1(65665624), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneDTNBP1

GO:0031175

neuron projection development

16980328

TgenePITPNC1

GO:0015914

phospholipid transport

22822086


check buttonFusion gene breakpoints across DTNBP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PITPNC1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4TGCTTCGA-2G-AALW-01ADTNBP1chr6

15663045

-PITPNC1chr17

65665624

+
ChimerDB4TGCTTCGA-2G-AALWDTNBP1chr6

15663045

-PITPNC1chr17

65665624

+


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Fusion Gene ORF analysis for DTNBP1-PITPNC1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000338950ENST00000299954DTNBP1chr6

15663045

-PITPNC1chr17

65665624

+
In-frameENST00000338950ENST00000335257DTNBP1chr6

15663045

-PITPNC1chr17

65665624

+
In-frameENST00000338950ENST00000580974DTNBP1chr6

15663045

-PITPNC1chr17

65665624

+
In-frameENST00000338950ENST00000581322DTNBP1chr6

15663045

-PITPNC1chr17

65665624

+
In-frameENST00000344537ENST00000299954DTNBP1chr6

15663045

-PITPNC1chr17

65665624

+
In-frameENST00000344537ENST00000335257DTNBP1chr6

15663045

-PITPNC1chr17

65665624

+
In-frameENST00000344537ENST00000580974DTNBP1chr6

15663045

-PITPNC1chr17

65665624

+
In-frameENST00000344537ENST00000581322DTNBP1chr6

15663045

-PITPNC1chr17

65665624

+
In-frameENST00000355917ENST00000299954DTNBP1chr6

15663045

-PITPNC1chr17

65665624

+
In-frameENST00000355917ENST00000335257DTNBP1chr6

15663045

-PITPNC1chr17

65665624

+
In-frameENST00000355917ENST00000580974DTNBP1chr6

15663045

-PITPNC1chr17

65665624

+
In-frameENST00000355917ENST00000581322DTNBP1chr6

15663045

-PITPNC1chr17

65665624

+
intron-3CDSENST00000462989ENST00000299954DTNBP1chr6

15663045

-PITPNC1chr17

65665624

+
intron-3CDSENST00000462989ENST00000335257DTNBP1chr6

15663045

-PITPNC1chr17

65665624

+
intron-3CDSENST00000462989ENST00000580974DTNBP1chr6

15663045

-PITPNC1chr17

65665624

+
intron-3CDSENST00000462989ENST00000581322DTNBP1chr6

15663045

-PITPNC1chr17

65665624

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000344537DTNBP1chr615663045-ENST00000580974PITPNC1chr1765665624+5253229651247134
ENST00000344537DTNBP1chr615663045-ENST00000299954PITPNC1chr1765665624+1526229651247134
ENST00000344537DTNBP1chr615663045-ENST00000335257PITPNC1chr1765665624+1407229271765164
ENST00000344537DTNBP1chr615663045-ENST00000581322PITPNC1chr1765665624+891229271765164
ENST00000355917DTNBP1chr615663045-ENST00000580974PITPNC1chr1765665624+5251227649245134
ENST00000355917DTNBP1chr615663045-ENST00000299954PITPNC1chr1765665624+1524227649245134
ENST00000355917DTNBP1chr615663045-ENST00000335257PITPNC1chr1765665624+1405227269763164
ENST00000355917DTNBP1chr615663045-ENST00000581322PITPNC1chr1765665624+889227269763164
ENST00000338950DTNBP1chr615663045-ENST00000580974PITPNC1chr1765665624+5186162503817104
ENST00000338950DTNBP1chr615663045-ENST00000299954PITPNC1chr1765665624+1459162584180134
ENST00000338950DTNBP1chr615663045-ENST00000335257PITPNC1chr1765665624+1340162204698164
ENST00000338950DTNBP1chr615663045-ENST00000581322PITPNC1chr1765665624+824162204698164

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000344537ENST00000580974DTNBP1chr615663045-PITPNC1chr1765665624+0.074819870.9251801
ENST00000344537ENST00000299954DTNBP1chr615663045-PITPNC1chr1765665624+0.0489053540.9510946
ENST00000344537ENST00000335257DTNBP1chr615663045-PITPNC1chr1765665624+0.0138153590.98618466
ENST00000344537ENST00000581322DTNBP1chr615663045-PITPNC1chr1765665624+0.0146176610.9853823
ENST00000355917ENST00000580974DTNBP1chr615663045-PITPNC1chr1765665624+0.0749387150.9250612
ENST00000355917ENST00000299954DTNBP1chr615663045-PITPNC1chr1765665624+0.047496320.9525036
ENST00000355917ENST00000335257DTNBP1chr615663045-PITPNC1chr1765665624+0.0134461890.98655385
ENST00000355917ENST00000581322DTNBP1chr615663045-PITPNC1chr1765665624+0.0156527250.9843472
ENST00000338950ENST00000580974DTNBP1chr615663045-PITPNC1chr1765665624+0.076537170.9234628
ENST00000338950ENST00000299954DTNBP1chr615663045-PITPNC1chr1765665624+0.0447103530.9552897
ENST00000338950ENST00000335257DTNBP1chr615663045-PITPNC1chr1765665624+0.0106131730.9893868
ENST00000338950ENST00000581322DTNBP1chr615663045-PITPNC1chr1765665624+0.0202881430.97971183

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Fusion Genomic Features for DTNBP1-PITPNC1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DTNBP1chr615663044-PITPNC1chr1765665623+1.99E-060.999998
DTNBP1chr615663044-PITPNC1chr1765665623+1.99E-060.999998
DTNBP1chr615663044-PITPNC1chr1765665623+1.99E-060.999998
DTNBP1chr615663044-PITPNC1chr1765665623+1.99E-060.999998

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for DTNBP1-PITPNC1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:15663045/chr17:65665624)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DTNBP1

Q96EV8

.
FUNCTION: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Associates with the BLOC-2 complex to facilitate the transport of TYRP1 independent of AP-3 function. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. Plays a role in the regulation of cell surface exposure of DRD2. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation. Appears to promote neuronal transmission and viability through regulating the expression of SNAP25 and SYN1, modulating PI3-kinase-Akt signaling and influencing glutamatergic release. Regulates the expression of SYN1 through binding to its promoter. Modulates prefrontal cortical activity via the dopamine/D2 pathway. {ECO:0000269|PubMed:15345706, ECO:0000269|PubMed:16837549, ECO:0000269|PubMed:17182842, ECO:0000269|PubMed:17989303, ECO:0000269|PubMed:19094965, ECO:0000269|PubMed:20180862, ECO:0000269|PubMed:20921223}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDTNBP1chr6:15663045chr17:65665624ENST00000338950-1988_18118304.0Coiled coilOntology_term=ECO:0000255
HgeneDTNBP1chr6:15663045chr17:65665624ENST00000344537-11088_18118352.0Coiled coilOntology_term=ECO:0000255
HgeneDTNBP1chr6:15663045chr17:65665624ENST00000338950-19173_33118304.0RegionNote=Dysbindin
HgeneDTNBP1chr6:15663045chr17:65665624ENST00000344537-110173_33118352.0RegionNote=Dysbindin


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Fusion Gene Sequence for DTNBP1-PITPNC1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>24383_24383_1_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000338950_PITPNC1_chr17_65665624_ENST00000299954_length(transcript)=1459nt_BP=162nt
GTGCGGGGCGCGCGGTGACAGCGCGGGGTTGGCGGCGTGGGACCCAGGGGGCGACAGAGGCAGCAGCAGCCCGAGGCCTGAGGAGAGGAG
ACCGGCGGCGGCGGCAATGCTGGAGACCCTTCGCGAGCGGCTGCTGAGCGTGCAGCAGGATTTCACCTCCGGGATCCTAAGCACTTCAAG
TCAGAGAAGACAGGACGGGGACAGTTGAGGGAAGGCTGGAGAGATAGTCATCAGCCTATCATGTGCTCCTACAAGCTGGTGACTGTGAAG
TTTGAGGTCTGGGGGCTTCAGACCAGAGTGGAACAATTTGTACACAAGGTGGTCCGAGACATTCTGCTGATTGGACATAGACAGGCTTTT
GCATGGGTTGATGAGTGGTATGATATGACAATGGATGATGTTCGGGAATACGAGAAAAACATGCATGAACAAACCAACATAAAAGTTTGC
AATCAGCATTCCTCCCCTGTGGATGACATAGAGAGTCATGCCCAAACAAGTACATGACAATGGATGAAGTCCGAGAATTTGAACGAGCCA
CTCAGGAAGCCACCAACAAGAAAATCGGCATTTTCCCACCTGCAATTTCTATCTCCAGCATCCCCCTGCTGCCTTCTTCCGTCCGCAGTG
CGCCTTCTAGTGCTCCATCCACCCCTCTCTCCACAGACGCACCCGAATTTCTGTCCGTTCCCAAAGATCGGCCCCGGAAAAAGTCTGCCC
CAGAAACTCTCACACTTCCAGACCCTGAGAAAAAAGCCACCCTGAATTTACCCGGCATGCACTCTTCAGATAAGCCATGTCGGCCCAAAT
CTGAGTAACTTTATATAAATATCTCATGGGGTTTTATATTTTCATTTGTTGTTGTTGTTTTTTTTTAAGAATCTTCTGATAGAGAAAAAG
ACTGCTTTGTCACTCAAACATGTTCCTTCGACCTTTCAGTGTGCATGTGACTCAGTAACTTCACATAGAATATGATTCCCTAAGTATGCT
ACACAGCATCATATTAGATGTAAGATGTAAGACTTGCAAAGGACAGAAGGAATCTTCTGTAACCACATAGCTGTATGCCAGAGAGGAAGC
CTTGTTATTGGGCATTTGATGAGGTTTGGCATGGACTTCAAGGATAAATGAATGAAAACTTTGCACCACTTTTGTTACAAGGTACGGTAG
AAAATAGTGAAGTCAGTTTCCTCTCATCAAATCTAAAATTCTCCAAAATACTCTCAGGCATAACATACTTAGCTGTTAAATTTTGAACTG
CTAATTACTAATACTTGAATACCAATAGTTACTGAGATTCCTATTTTGTGGTTAGTCTGACTCAGGATTTGGAGCCTAATTAACTCTAAA
CTTTTGAAAATTTTAATCATCAAGCTATAGAGGCTCCAAGTGCAATTAATAATAACTCATTTATACCTTCCACAGAATTTAATAAAGATT

>24383_24383_1_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000338950_PITPNC1_chr17_65665624_ENST00000299954_length(amino acids)=134AA_BP=
MQVGKCRFSCWWLPEWLVQILGLHPLSCTCLGMTLYVIHRGGMLIANFYVGLFMHVFLVFPNIIHCHIIPLINPCKSLSMSNQQNVSDHL

--------------------------------------------------------------
>24383_24383_2_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000338950_PITPNC1_chr17_65665624_ENST00000335257_length(transcript)=1340nt_BP=162nt
GTGCGGGGCGCGCGGTGACAGCGCGGGGTTGGCGGCGTGGGACCCAGGGGGCGACAGAGGCAGCAGCAGCCCGAGGCCTGAGGAGAGGAG
ACCGGCGGCGGCGGCAATGCTGGAGACCCTTCGCGAGCGGCTGCTGAGCGTGCAGCAGGATTTCACCTCCGGGATCCTAAGCACTTCAAG
TCAGAGAAGACAGGACGGGGACAGTTGAGGGAAGGCTGGAGAGATAGTCATCAGCCTATCATGTGCTCCTACAAGCTGGTGACTGTGAAG
TTTGAGGTCTGGGGGCTTCAGACCAGAGTGGAACAATTTGTACACAAGGTGGTCCGAGACATTCTGCTGATTGGACATAGACAGGCTTTT
GCATGGGTTGATGAGTGGTATGACATGACAATGGATGAAGTCCGAGAATTTGAACGAGCCACTCAGGAAGCCACCAACAAGAAAATCGGC
ATTTTCCCACCTGCAATTTCTATCTCCAGCATCCCCCTGCTGCCTTCTTCCGTCCGCAGTGCGCCTTCTAGTGCTCCATCCACCCCTCTC
TCCACAGACGCACCCGAATTTCTGTCCGTTCCCAAAGATCGGCCCCGGAAAAAGTCTGCCCCAGAAACTCTCACACTTCCAGACCCTGAG
AAAAAAGCCACCCTGAATTTACCCGGCATGCACTCTTCAGATAAGCCATGTCGGCCCAAATCTGAGTAACTTTATATAAATATCTCATGG
GGTTTTATATTTTCATTTGTTGTTGTTGTTTTTTTTTAAGAATCTTCTGATAGAGAAAAAGACTGCTTTGTCACTCAAACATGTTCCTTC
GACCTTTCAGTGTGCATGTGACTCAGTAACTTCACATAGAATATGATTCCCTAAGTATGCTACACAGCATCATATTAGATGTAAGATGTA
AGACTTGCAAAGGACAGAAGGAATCTTCTGTAACCACATAGCTGTATGCCAGAGAGGAAGCCTTGTTATTGGGCATTTGATGAGGTTTGG
CATGGACTTCAAGGATAAATGAATGAAAACTTTGCACCACTTTTGTTACAAGGTACGGTAGAAAATAGTGAAGTCAGTTTCCTCTCATCA
AATCTAAAATTCTCCAAAATACTCTCAGGCATAACATACTTAGCTGTTAAATTTTGAACTGCTAATTACTAATACTTGAATACCAATAGT
TACTGAGATTCCTATTTTGTGGTTAGTCTGACTCAGGATTTGGAGCCTAATTAACTCTAAACTTTTGAAAATTTTAATCATCAAGCTATA

>24383_24383_2_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000338950_PITPNC1_chr17_65665624_ENST00000335257_length(amino acids)=164AA_BP=
MREGWRDSHQPIMCSYKLVTVKFEVWGLQTRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDEVREFERATQEATNKKIGIFPPAISI

--------------------------------------------------------------
>24383_24383_3_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000338950_PITPNC1_chr17_65665624_ENST00000580974_length(transcript)=5186nt_BP=162nt
GTGCGGGGCGCGCGGTGACAGCGCGGGGTTGGCGGCGTGGGACCCAGGGGGCGACAGAGGCAGCAGCAGCCCGAGGCCTGAGGAGAGGAG
ACCGGCGGCGGCGGCAATGCTGGAGACCCTTCGCGAGCGGCTGCTGAGCGTGCAGCAGGATTTCACCTCCGGGATCCTAAGCACTTCAAG
TCAGAGAAGACAGGACGGGGACAGTTGAGGGAAGGCTGGAGAGATAGTCATCAGCCTATCATGTGCTCCTACAAGCTGGTGACTGTGAAG
TTTGAGGTCTGGGGGCTTCAGACCAGAGTGGAACAATTTGTACACAAGGTGGTCCGAGACATTCTGCTGATTGGACATAGACAGGCTTTT
GCATGGGTTGATGAGTGGTATGATATGACAATGGATGATGTTCGGGAATACGAGAAAAACATGCATGAACAAACCAACATAAAAGTTTGC
AATCAGCATTCCTCCCCTGTGGATGACATAGAGAGTCATGCCCAAACAAGTACATGACAATGGATGAAGTCCGAGAATTTGAACGAGCCA
CTCAGGAAGCCACCAACAAGAAAATCGGCATTTTCCCACCTGCAATTTCTATCTCCAGCATCCCCCTGCTGCCTTCTTCCGTCCGCAGTG
CGCCTTCTAGTGCTCCATCCACCCCTCTCTCCACAGACGCACCCGAATTTCTGTCCGTTCCCAAAGATCGGCCCCGGAAAAAGTCTGCCC
CAGAAACTCTCACACTTCCAGACCCTGAGAAAAAAGCCACCCTGAATTTACCCGGCATGCACTCTTCAGATAAGCCATGTCGGCCCAAAT
CTGAGTAACTTTATATAAATATCTCATGGGGTTTTATATTTTCATTTGTTGTTGTTGTTTTTTTTTAAGAATCTTCTGATAGAGAAAAAG
ACTGCTTTGTCACTCAAACATGTTCCTTCGACCTTTCAGTGTGCATGTGACTCAGTAACTTCACATAGAATATGATTCCCTAAGTATGCT
ACACAGCATCATATTAGATGTAAGATGTAAGACTTGCAAAGGACAGAAGGAATCTTCTGTAACCACATAGCTGTATGCCAGAGAGGAAGC
CTTGTTATTGGGCATTTGATGAGGTTTGGCATGGACTTCAAGGATAAATGAATGAAAACTTTGCACCACTTTTGTTACAAGGTACGGTAG
AAAATAGTGAAGTCAGTTTCCTCTCATCAAATCTAAAATTCTCCAAAATACTCTCAGGCATAACATACTTAGCTGTTAAATTTTGAACTG
CTAATTACTAATACTTGAATACCAATAGTTACTGAGATTCCTATTTTGTGGTTAGTCTGACTCAGGATTTGGAGCCTAATTAACTCTAAA
CTTTTGAAAATTTTAATCATCAAGCTATAGAGGCTCCAAGTGCAATTAATAATAACTCATTTATACCTTCCACAGAATTTAATAAAGATT
CTACTTGTTTCTGTCTTTTAATAACTTTCCCCTTTTGTGCCCTTGTGGCCTCAGAAATCCTTAAGAATTGCATGGATGAATGTGACCATA
ACTGATTTTGGAATGGTTCAGTTTAGGAACCAAGAGGCCCAGGTGAGGCAACATCTTTTTTCTCTACAGGTACCAACAAACCTTGACTTG
TCAGCTTCCATCATCAATTAAGATTCTCAGAATTTGCAATTAATTGAATAGAATTCATTTACTATCTGCCCACTCAAAGAAGTACAAGGG
TAGAGTAAGCTAACTGGGCTTTAACATGGTCAGAATGTCTGGTGCATGAACTATAAAAAAGAGAACTGTCTCCCATCCCCTTCCTTGTTT
TACTCTTAGTAACATCCAGAATTCCCTGGAACAGATTGCCTACCACCAGACCTTAGAAAAGACTGTCATTCTCTTGCTCCTTACTTGAAA
TACAAATATTGGGAATGTCACAGACATCAAGCAACTACTGTCAAGTGGGAGGAGAGAATGAGCAGAATTGCTGACTCCTATTTGTAGAGT
GAAAAGGAGGAGTGATAATAGATGCCCTTCTGTCTAGCTTTCCTTTCTTCAACTAGTGGTAATGCAAGATTAGAATCAAGGTTGACAGGA
GGCAAGGTCACTCACTGAAGTGACAGAAAGACAATTCTCCTTTGCTCCAAAGAGAGAAATCTGTCACCTTTGCACCTCACTGCCTTTAAA
CACAGACGGGAGGGCAGGCCAAATCTCAGCATTGACTTTTGTCCTCCAAGAGAGGAAGAGAAGAAGTAATTGGGCAACTTGGAGGCCCAC
GCCCCAGCTAGCCTTCCTGATCGTAACCTCCAACCTCAGGAAAGGGACCTTCCCAAAACACAGATCCCAAAGGAAACAAAATAGACCAAG
GAGCATAATCTGCTTCTCTCACACAGCCTCTCTGCCAGTGGACCCTGCCTGCTTCCCTCTCAGTGCTCAGCACTCTGTGTAGTGTCTTTC
AGGTTGATACACTCTCCCAAGGTGCAGGCGCTGGCCCCATGAGCCCAGCACCAAAGTTTTCTAAGTCATAGGTCAGACTGTCAAGATCAT
TTCTTTATCTATAGGTTGATATTTAGCTTAAAAAAAAAGAATAAACCTAGAACTCAAAGGAAACCTGTTGCAAATAGCTTAGATCAACAG
TGTATCTCTTCCCTAAGAATGATAGTATCTTAGTAAGACACCTTCTATGCATGGTATGGAAGCATGATTTTTGCTTGTGGGAAAACCTAA
TATTTTATCAGACCCCTCGGACTTCTCAATCCCTCCCTCTCCACACAGTAGTACTTAATGAAAATGTTTTGCTTTAGAGAGCAAAATGCT
ACTTTCAGAAGACACTGAAATAGTATATGTATTTGCTTACCATTTGCAAGCTAAAATCAAGGTGGGATGGGGTCATTATTTTCACATAGA
ATGTATTTATTTTGTGCAGGCTGTTAAACACATCTGGCACCTAGTTTTTCCATTAAGAGCATTGCTATTTTCCCTTTTTATAAAGTAGCT
TCTGCTGTCAAGGTTAACAATTCTATATGCTTTAGGAAGCTAAGTTCTAATTTCCTTTTGTGAGTTTCATTTCTTTTATAACCAGTATGT
TACCACAGACATCAGTTGCAAAGCTACGATGATAGTGTGATTCTTAGCCGAAAAAAAAGCGTGTGCTCTTAAAGTATGTTCAGTTTTTCT
GTCTACATATGCTTTGTGTGAGTTAAAAAGGGGGTGGGTGGTGTAAATATTCCTTTAGCTGCTTTGCATATTTAACCCAGTCATCAAAAG
GCATAAATGACTTCAATATTTTATATATCTTGGTTTTCAAGTATCATTTCACATTCTCTATACATGACTTTGTTATTGTGGAATACAAGC
CTGCAATGGATGTATATATACAGAACATTAATAATTCTTAGAAGGATGGAAGCCAAATGGCTGCATGATGGAAATTAGAAGAAAAAAAAA
GCAGAAACTTGAATTTGCTAAGCATGTTTGGGGGGAAATAGAATCCTTAACTCAGTGCCTCTGTCTGCGATATGGAAACCTTCAACTTTG
TTCACCAAAATTGTATTATACCTGTGTATATATATATATATATATATATATAAATATAAATATAGTATAGTGAATCAGACACCATCAGTT
TTAAGTCTCTGGTAGCCAAACTTAAATAAATAATCCATAGAATATCACATACGTTCACTCCATCTTCATCTCTGAAGTTAGTGGAGACCA
TCAAAATGACTGTACATTTCATAACTCTGGGAAGATTTCAAATGTGAAGTGCCCCTGTGCATTTTCTTGGCCATAGCACGGCATTCTTGC
TTTAGCTGTGCTTTCCTGGGATGAGAAGATCTTGGTGTATTTAACACATAAGCTTTGTTAGAAATCACCTCTGAAGATCATTTCATTTTC
TCACTTTGGGTTGTTGCAAGACAAAGCAAAGGAAAAGGAACACAATGAAGGAGGCCGTGACATTTTTAGTTGCCACCGTTGTAACTCAAA
CAATATGGGTTTGTTGGTGAACTGATTTATCAAGGCTTCTGTTACGGTTTTGCATCTGTGTGTGAGGAAAATTTTAATTTATTTGGAAGT
ATTTATTAGCCATGTTGTTGGTCCTGAAAATAAATCTCTAAGTAGCACAGTTGTGGGTATATTATGCAGACACTTACCACAATACCTGCA
AAAGTAACTGTGGTTTTCTTTCAAGACACTGTAATAAACAGTGAACTAAGAGAATAGATTCTGATACATCTCGATAAATCATTCTCTGCA
AAAGTTTCAGGGCTAATGTATTTATGTGTATTTTTAAATTCTACTTTCTTTGGCATCTCTTCATGGCTCAGCGACAACAAAGTAATAGGT
CATTGGCTGGCTTACGTCGATAGGAATTTTACTCTTAAGAAGGGCCAGTGTATAGCTGACTCTACATATAATGTGTAATCAGATAATCCA
ATAGAGAGGAATTGTCCAAATAGTTTTAGTACCTTTCTGATCATCTGACTCAGTAGGCTAGGAGACAATCTGTCATCTGAGCCATAGTTC
TTGAGATTTAAAAAGTCTGTCCAGTGACTGCAATCTGATTATGAATAAACTATTTTAACTATTCATTCTTGCTGAAACTGAAGTGTACAC
AATAGCACACTGTTGGCATGCTGAGGCAAAACATTGGGTTCTTTTGTGTTCTACCTTCAAAACAATCTGTTTGCATTTGAAATATAAGTG
TTTAAGCTTTTTAGGAGTTAGTGTAATAAGAGAATGTGAATATGTTGGGAAATTTTCAGATGCCATTAATAATTGTAATTTTGTTGTTAA
ATTAACAAGGACTTTAGGATAAGCCTCTTGATGTTTTTTGCTTTAAATTGAAAGCATGTCTGTCAAATTGCAAGTCTCCCTTCAGTTTCT
ATATATCACCCAGGAGAGGGTCTCTGAGTTGGTGTTGTACCTGTACCACTCACATGTAGCTCAAGTGTAATTTGTAGTGTTTACATTCAA
GCTGGGATCTTGATTGGTTAAATTAATCCACATACCACTGCCACTGCTGAAGGACCAGGTGTTGGAATACACAGCATTACAGACTATAAG
CAAAGCAAACAAAAGTTGATCCTTACATATGCCATCCTTCTGTGTCATTTTGTGGCTGTTCTGTGTTTTTCTTCCTAGTTATTTATTATT

>24383_24383_3_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000338950_PITPNC1_chr17_65665624_ENST00000580974_length(amino acids)=104AA_BP=
MTMDEVREFERATQEATNKKIGIFPPAISISSIPLLPSSVRSAPSSAPSTPLSTDAPEFLSVPKDRPRKKSAPETLTLPDPEKKATLNLP

--------------------------------------------------------------
>24383_24383_4_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000338950_PITPNC1_chr17_65665624_ENST00000581322_length(transcript)=824nt_BP=162nt
GTGCGGGGCGCGCGGTGACAGCGCGGGGTTGGCGGCGTGGGACCCAGGGGGCGACAGAGGCAGCAGCAGCCCGAGGCCTGAGGAGAGGAG
ACCGGCGGCGGCGGCAATGCTGGAGACCCTTCGCGAGCGGCTGCTGAGCGTGCAGCAGGATTTCACCTCCGGGATCCTAAGCACTTCAAG
TCAGAGAAGACAGGACGGGGACAGTTGAGGGAAGGCTGGAGAGATAGTCATCAGCCTATCATGTGCTCCTACAAGCTGGTGACTGTGAAG
TTTGAGGTCTGGGGGCTTCAGACCAGAGTGGAACAATTTGTACACAAGGTGGTCCGAGACATTCTGCTGATTGGACATAGACAGGCTTTT
GCATGGGTTGATGAGTGGTATGACATGACAATGGATGAAGTCCGAGAATTTGAACGAGCCACTCAGGAAGCCACCAACAAGAAAATCGGC
ATTTTCCCACCTGCAATTTCTATCTCCAGCATCCCCCTGCTGCCTTCTTCCGTCCGCAGTGCGCCTTCTAGTGCTCCATCCACCCCTCTC
TCCACAGACGCACCCGAATTTCTGTCCGTTCCCAAAGATCGGCCCCGGAAAAAGTCTGCCCCAGAAACTCTCACACTTCCAGACCCTGAG
AAAAAAGCCACCCTGAATTTACCCGGCATGCACTCTTCAGATAAGCCATGTCGGCCCAAATCTGAGTAACTTTATATAAATATCTCATGG
GGTTTTATATTTTCATTTGTTGTTGTTGTTTTTTTTTAAGAATCTTCTGATAGAGAAAAAGACTGCTTTGTCACTCAAACATGTTCCTTC

>24383_24383_4_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000338950_PITPNC1_chr17_65665624_ENST00000581322_length(amino acids)=164AA_BP=
MREGWRDSHQPIMCSYKLVTVKFEVWGLQTRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDEVREFERATQEATNKKIGIFPPAISI

--------------------------------------------------------------
>24383_24383_5_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000344537_PITPNC1_chr17_65665624_ENST00000299954_length(transcript)=1526nt_BP=229nt
ACGCGGAAGGGGCTGGGGTTGCGGCGCGGCGGCGAGGACCAGACCGGGGGCGGGGCCGGTAGTGGGAGTGCGGGGCGCGCGGTGACAGCG
CGGGGTTGGCGGCGTGGGACCCAGGGGGCGACAGAGGCAGCAGCAGCCCGAGGCCTGAGGAGAGGAGACCGGCGGCGGCGGCAATGCTGG
AGACCCTTCGCGAGCGGCTGCTGAGCGTGCAGCAGGATTTCACCTCCGGGATCCTAAGCACTTCAAGTCAGAGAAGACAGGACGGGGACA
GTTGAGGGAAGGCTGGAGAGATAGTCATCAGCCTATCATGTGCTCCTACAAGCTGGTGACTGTGAAGTTTGAGGTCTGGGGGCTTCAGAC
CAGAGTGGAACAATTTGTACACAAGGTGGTCCGAGACATTCTGCTGATTGGACATAGACAGGCTTTTGCATGGGTTGATGAGTGGTATGA
TATGACAATGGATGATGTTCGGGAATACGAGAAAAACATGCATGAACAAACCAACATAAAAGTTTGCAATCAGCATTCCTCCCCTGTGGA
TGACATAGAGAGTCATGCCCAAACAAGTACATGACAATGGATGAAGTCCGAGAATTTGAACGAGCCACTCAGGAAGCCACCAACAAGAAA
ATCGGCATTTTCCCACCTGCAATTTCTATCTCCAGCATCCCCCTGCTGCCTTCTTCCGTCCGCAGTGCGCCTTCTAGTGCTCCATCCACC
CCTCTCTCCACAGACGCACCCGAATTTCTGTCCGTTCCCAAAGATCGGCCCCGGAAAAAGTCTGCCCCAGAAACTCTCACACTTCCAGAC
CCTGAGAAAAAAGCCACCCTGAATTTACCCGGCATGCACTCTTCAGATAAGCCATGTCGGCCCAAATCTGAGTAACTTTATATAAATATC
TCATGGGGTTTTATATTTTCATTTGTTGTTGTTGTTTTTTTTTAAGAATCTTCTGATAGAGAAAAAGACTGCTTTGTCACTCAAACATGT
TCCTTCGACCTTTCAGTGTGCATGTGACTCAGTAACTTCACATAGAATATGATTCCCTAAGTATGCTACACAGCATCATATTAGATGTAA
GATGTAAGACTTGCAAAGGACAGAAGGAATCTTCTGTAACCACATAGCTGTATGCCAGAGAGGAAGCCTTGTTATTGGGCATTTGATGAG
GTTTGGCATGGACTTCAAGGATAAATGAATGAAAACTTTGCACCACTTTTGTTACAAGGTACGGTAGAAAATAGTGAAGTCAGTTTCCTC
TCATCAAATCTAAAATTCTCCAAAATACTCTCAGGCATAACATACTTAGCTGTTAAATTTTGAACTGCTAATTACTAATACTTGAATACC
AATAGTTACTGAGATTCCTATTTTGTGGTTAGTCTGACTCAGGATTTGGAGCCTAATTAACTCTAAACTTTTGAAAATTTTAATCATCAA

>24383_24383_5_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000344537_PITPNC1_chr17_65665624_ENST00000299954_length(amino acids)=134AA_BP=
MQVGKCRFSCWWLPEWLVQILGLHPLSCTCLGMTLYVIHRGGMLIANFYVGLFMHVFLVFPNIIHCHIIPLINPCKSLSMSNQQNVSDHL

--------------------------------------------------------------
>24383_24383_6_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000344537_PITPNC1_chr17_65665624_ENST00000335257_length(transcript)=1407nt_BP=229nt
ACGCGGAAGGGGCTGGGGTTGCGGCGCGGCGGCGAGGACCAGACCGGGGGCGGGGCCGGTAGTGGGAGTGCGGGGCGCGCGGTGACAGCG
CGGGGTTGGCGGCGTGGGACCCAGGGGGCGACAGAGGCAGCAGCAGCCCGAGGCCTGAGGAGAGGAGACCGGCGGCGGCGGCAATGCTGG
AGACCCTTCGCGAGCGGCTGCTGAGCGTGCAGCAGGATTTCACCTCCGGGATCCTAAGCACTTCAAGTCAGAGAAGACAGGACGGGGACA
GTTGAGGGAAGGCTGGAGAGATAGTCATCAGCCTATCATGTGCTCCTACAAGCTGGTGACTGTGAAGTTTGAGGTCTGGGGGCTTCAGAC
CAGAGTGGAACAATTTGTACACAAGGTGGTCCGAGACATTCTGCTGATTGGACATAGACAGGCTTTTGCATGGGTTGATGAGTGGTATGA
CATGACAATGGATGAAGTCCGAGAATTTGAACGAGCCACTCAGGAAGCCACCAACAAGAAAATCGGCATTTTCCCACCTGCAATTTCTAT
CTCCAGCATCCCCCTGCTGCCTTCTTCCGTCCGCAGTGCGCCTTCTAGTGCTCCATCCACCCCTCTCTCCACAGACGCACCCGAATTTCT
GTCCGTTCCCAAAGATCGGCCCCGGAAAAAGTCTGCCCCAGAAACTCTCACACTTCCAGACCCTGAGAAAAAAGCCACCCTGAATTTACC
CGGCATGCACTCTTCAGATAAGCCATGTCGGCCCAAATCTGAGTAACTTTATATAAATATCTCATGGGGTTTTATATTTTCATTTGTTGT
TGTTGTTTTTTTTTAAGAATCTTCTGATAGAGAAAAAGACTGCTTTGTCACTCAAACATGTTCCTTCGACCTTTCAGTGTGCATGTGACT
CAGTAACTTCACATAGAATATGATTCCCTAAGTATGCTACACAGCATCATATTAGATGTAAGATGTAAGACTTGCAAAGGACAGAAGGAA
TCTTCTGTAACCACATAGCTGTATGCCAGAGAGGAAGCCTTGTTATTGGGCATTTGATGAGGTTTGGCATGGACTTCAAGGATAAATGAA
TGAAAACTTTGCACCACTTTTGTTACAAGGTACGGTAGAAAATAGTGAAGTCAGTTTCCTCTCATCAAATCTAAAATTCTCCAAAATACT
CTCAGGCATAACATACTTAGCTGTTAAATTTTGAACTGCTAATTACTAATACTTGAATACCAATAGTTACTGAGATTCCTATTTTGTGGT
TAGTCTGACTCAGGATTTGGAGCCTAATTAACTCTAAACTTTTGAAAATTTTAATCATCAAGCTATAGAGGCTCCAAGTGCAATTAATAA

>24383_24383_6_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000344537_PITPNC1_chr17_65665624_ENST00000335257_length(amino acids)=164AA_BP=
MREGWRDSHQPIMCSYKLVTVKFEVWGLQTRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDEVREFERATQEATNKKIGIFPPAISI

--------------------------------------------------------------
>24383_24383_7_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000344537_PITPNC1_chr17_65665624_ENST00000580974_length(transcript)=5253nt_BP=229nt
ACGCGGAAGGGGCTGGGGTTGCGGCGCGGCGGCGAGGACCAGACCGGGGGCGGGGCCGGTAGTGGGAGTGCGGGGCGCGCGGTGACAGCG
CGGGGTTGGCGGCGTGGGACCCAGGGGGCGACAGAGGCAGCAGCAGCCCGAGGCCTGAGGAGAGGAGACCGGCGGCGGCGGCAATGCTGG
AGACCCTTCGCGAGCGGCTGCTGAGCGTGCAGCAGGATTTCACCTCCGGGATCCTAAGCACTTCAAGTCAGAGAAGACAGGACGGGGACA
GTTGAGGGAAGGCTGGAGAGATAGTCATCAGCCTATCATGTGCTCCTACAAGCTGGTGACTGTGAAGTTTGAGGTCTGGGGGCTTCAGAC
CAGAGTGGAACAATTTGTACACAAGGTGGTCCGAGACATTCTGCTGATTGGACATAGACAGGCTTTTGCATGGGTTGATGAGTGGTATGA
TATGACAATGGATGATGTTCGGGAATACGAGAAAAACATGCATGAACAAACCAACATAAAAGTTTGCAATCAGCATTCCTCCCCTGTGGA
TGACATAGAGAGTCATGCCCAAACAAGTACATGACAATGGATGAAGTCCGAGAATTTGAACGAGCCACTCAGGAAGCCACCAACAAGAAA
ATCGGCATTTTCCCACCTGCAATTTCTATCTCCAGCATCCCCCTGCTGCCTTCTTCCGTCCGCAGTGCGCCTTCTAGTGCTCCATCCACC
CCTCTCTCCACAGACGCACCCGAATTTCTGTCCGTTCCCAAAGATCGGCCCCGGAAAAAGTCTGCCCCAGAAACTCTCACACTTCCAGAC
CCTGAGAAAAAAGCCACCCTGAATTTACCCGGCATGCACTCTTCAGATAAGCCATGTCGGCCCAAATCTGAGTAACTTTATATAAATATC
TCATGGGGTTTTATATTTTCATTTGTTGTTGTTGTTTTTTTTTAAGAATCTTCTGATAGAGAAAAAGACTGCTTTGTCACTCAAACATGT
TCCTTCGACCTTTCAGTGTGCATGTGACTCAGTAACTTCACATAGAATATGATTCCCTAAGTATGCTACACAGCATCATATTAGATGTAA
GATGTAAGACTTGCAAAGGACAGAAGGAATCTTCTGTAACCACATAGCTGTATGCCAGAGAGGAAGCCTTGTTATTGGGCATTTGATGAG
GTTTGGCATGGACTTCAAGGATAAATGAATGAAAACTTTGCACCACTTTTGTTACAAGGTACGGTAGAAAATAGTGAAGTCAGTTTCCTC
TCATCAAATCTAAAATTCTCCAAAATACTCTCAGGCATAACATACTTAGCTGTTAAATTTTGAACTGCTAATTACTAATACTTGAATACC
AATAGTTACTGAGATTCCTATTTTGTGGTTAGTCTGACTCAGGATTTGGAGCCTAATTAACTCTAAACTTTTGAAAATTTTAATCATCAA
GCTATAGAGGCTCCAAGTGCAATTAATAATAACTCATTTATACCTTCCACAGAATTTAATAAAGATTCTACTTGTTTCTGTCTTTTAATA
ACTTTCCCCTTTTGTGCCCTTGTGGCCTCAGAAATCCTTAAGAATTGCATGGATGAATGTGACCATAACTGATTTTGGAATGGTTCAGTT
TAGGAACCAAGAGGCCCAGGTGAGGCAACATCTTTTTTCTCTACAGGTACCAACAAACCTTGACTTGTCAGCTTCCATCATCAATTAAGA
TTCTCAGAATTTGCAATTAATTGAATAGAATTCATTTACTATCTGCCCACTCAAAGAAGTACAAGGGTAGAGTAAGCTAACTGGGCTTTA
ACATGGTCAGAATGTCTGGTGCATGAACTATAAAAAAGAGAACTGTCTCCCATCCCCTTCCTTGTTTTACTCTTAGTAACATCCAGAATT
CCCTGGAACAGATTGCCTACCACCAGACCTTAGAAAAGACTGTCATTCTCTTGCTCCTTACTTGAAATACAAATATTGGGAATGTCACAG
ACATCAAGCAACTACTGTCAAGTGGGAGGAGAGAATGAGCAGAATTGCTGACTCCTATTTGTAGAGTGAAAAGGAGGAGTGATAATAGAT
GCCCTTCTGTCTAGCTTTCCTTTCTTCAACTAGTGGTAATGCAAGATTAGAATCAAGGTTGACAGGAGGCAAGGTCACTCACTGAAGTGA
CAGAAAGACAATTCTCCTTTGCTCCAAAGAGAGAAATCTGTCACCTTTGCACCTCACTGCCTTTAAACACAGACGGGAGGGCAGGCCAAA
TCTCAGCATTGACTTTTGTCCTCCAAGAGAGGAAGAGAAGAAGTAATTGGGCAACTTGGAGGCCCACGCCCCAGCTAGCCTTCCTGATCG
TAACCTCCAACCTCAGGAAAGGGACCTTCCCAAAACACAGATCCCAAAGGAAACAAAATAGACCAAGGAGCATAATCTGCTTCTCTCACA
CAGCCTCTCTGCCAGTGGACCCTGCCTGCTTCCCTCTCAGTGCTCAGCACTCTGTGTAGTGTCTTTCAGGTTGATACACTCTCCCAAGGT
GCAGGCGCTGGCCCCATGAGCCCAGCACCAAAGTTTTCTAAGTCATAGGTCAGACTGTCAAGATCATTTCTTTATCTATAGGTTGATATT
TAGCTTAAAAAAAAAGAATAAACCTAGAACTCAAAGGAAACCTGTTGCAAATAGCTTAGATCAACAGTGTATCTCTTCCCTAAGAATGAT
AGTATCTTAGTAAGACACCTTCTATGCATGGTATGGAAGCATGATTTTTGCTTGTGGGAAAACCTAATATTTTATCAGACCCCTCGGACT
TCTCAATCCCTCCCTCTCCACACAGTAGTACTTAATGAAAATGTTTTGCTTTAGAGAGCAAAATGCTACTTTCAGAAGACACTGAAATAG
TATATGTATTTGCTTACCATTTGCAAGCTAAAATCAAGGTGGGATGGGGTCATTATTTTCACATAGAATGTATTTATTTTGTGCAGGCTG
TTAAACACATCTGGCACCTAGTTTTTCCATTAAGAGCATTGCTATTTTCCCTTTTTATAAAGTAGCTTCTGCTGTCAAGGTTAACAATTC
TATATGCTTTAGGAAGCTAAGTTCTAATTTCCTTTTGTGAGTTTCATTTCTTTTATAACCAGTATGTTACCACAGACATCAGTTGCAAAG
CTACGATGATAGTGTGATTCTTAGCCGAAAAAAAAGCGTGTGCTCTTAAAGTATGTTCAGTTTTTCTGTCTACATATGCTTTGTGTGAGT
TAAAAAGGGGGTGGGTGGTGTAAATATTCCTTTAGCTGCTTTGCATATTTAACCCAGTCATCAAAAGGCATAAATGACTTCAATATTTTA
TATATCTTGGTTTTCAAGTATCATTTCACATTCTCTATACATGACTTTGTTATTGTGGAATACAAGCCTGCAATGGATGTATATATACAG
AACATTAATAATTCTTAGAAGGATGGAAGCCAAATGGCTGCATGATGGAAATTAGAAGAAAAAAAAAGCAGAAACTTGAATTTGCTAAGC
ATGTTTGGGGGGAAATAGAATCCTTAACTCAGTGCCTCTGTCTGCGATATGGAAACCTTCAACTTTGTTCACCAAAATTGTATTATACCT
GTGTATATATATATATATATATATATATAAATATAAATATAGTATAGTGAATCAGACACCATCAGTTTTAAGTCTCTGGTAGCCAAACTT
AAATAAATAATCCATAGAATATCACATACGTTCACTCCATCTTCATCTCTGAAGTTAGTGGAGACCATCAAAATGACTGTACATTTCATA
ACTCTGGGAAGATTTCAAATGTGAAGTGCCCCTGTGCATTTTCTTGGCCATAGCACGGCATTCTTGCTTTAGCTGTGCTTTCCTGGGATG
AGAAGATCTTGGTGTATTTAACACATAAGCTTTGTTAGAAATCACCTCTGAAGATCATTTCATTTTCTCACTTTGGGTTGTTGCAAGACA
AAGCAAAGGAAAAGGAACACAATGAAGGAGGCCGTGACATTTTTAGTTGCCACCGTTGTAACTCAAACAATATGGGTTTGTTGGTGAACT
GATTTATCAAGGCTTCTGTTACGGTTTTGCATCTGTGTGTGAGGAAAATTTTAATTTATTTGGAAGTATTTATTAGCCATGTTGTTGGTC
CTGAAAATAAATCTCTAAGTAGCACAGTTGTGGGTATATTATGCAGACACTTACCACAATACCTGCAAAAGTAACTGTGGTTTTCTTTCA
AGACACTGTAATAAACAGTGAACTAAGAGAATAGATTCTGATACATCTCGATAAATCATTCTCTGCAAAAGTTTCAGGGCTAATGTATTT
ATGTGTATTTTTAAATTCTACTTTCTTTGGCATCTCTTCATGGCTCAGCGACAACAAAGTAATAGGTCATTGGCTGGCTTACGTCGATAG
GAATTTTACTCTTAAGAAGGGCCAGTGTATAGCTGACTCTACATATAATGTGTAATCAGATAATCCAATAGAGAGGAATTGTCCAAATAG
TTTTAGTACCTTTCTGATCATCTGACTCAGTAGGCTAGGAGACAATCTGTCATCTGAGCCATAGTTCTTGAGATTTAAAAAGTCTGTCCA
GTGACTGCAATCTGATTATGAATAAACTATTTTAACTATTCATTCTTGCTGAAACTGAAGTGTACACAATAGCACACTGTTGGCATGCTG
AGGCAAAACATTGGGTTCTTTTGTGTTCTACCTTCAAAACAATCTGTTTGCATTTGAAATATAAGTGTTTAAGCTTTTTAGGAGTTAGTG
TAATAAGAGAATGTGAATATGTTGGGAAATTTTCAGATGCCATTAATAATTGTAATTTTGTTGTTAAATTAACAAGGACTTTAGGATAAG
CCTCTTGATGTTTTTTGCTTTAAATTGAAAGCATGTCTGTCAAATTGCAAGTCTCCCTTCAGTTTCTATATATCACCCAGGAGAGGGTCT
CTGAGTTGGTGTTGTACCTGTACCACTCACATGTAGCTCAAGTGTAATTTGTAGTGTTTACATTCAAGCTGGGATCTTGATTGGTTAAAT
TAATCCACATACCACTGCCACTGCTGAAGGACCAGGTGTTGGAATACACAGCATTACAGACTATAAGCAAAGCAAACAAAAGTTGATCCT
TACATATGCCATCCTTCTGTGTCATTTTGTGGCTGTTCTGTGTTTTTCTTCCTAGTTATTTATTATTGTTAATAACTTACTTTTTCTTAC

>24383_24383_7_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000344537_PITPNC1_chr17_65665624_ENST00000580974_length(amino acids)=134AA_BP=
MQVGKCRFSCWWLPEWLVQILGLHPLSCTCLGMTLYVIHRGGMLIANFYVGLFMHVFLVFPNIIHCHIIPLINPCKSLSMSNQQNVSDHL

--------------------------------------------------------------
>24383_24383_8_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000344537_PITPNC1_chr17_65665624_ENST00000581322_length(transcript)=891nt_BP=229nt
ACGCGGAAGGGGCTGGGGTTGCGGCGCGGCGGCGAGGACCAGACCGGGGGCGGGGCCGGTAGTGGGAGTGCGGGGCGCGCGGTGACAGCG
CGGGGTTGGCGGCGTGGGACCCAGGGGGCGACAGAGGCAGCAGCAGCCCGAGGCCTGAGGAGAGGAGACCGGCGGCGGCGGCAATGCTGG
AGACCCTTCGCGAGCGGCTGCTGAGCGTGCAGCAGGATTTCACCTCCGGGATCCTAAGCACTTCAAGTCAGAGAAGACAGGACGGGGACA
GTTGAGGGAAGGCTGGAGAGATAGTCATCAGCCTATCATGTGCTCCTACAAGCTGGTGACTGTGAAGTTTGAGGTCTGGGGGCTTCAGAC
CAGAGTGGAACAATTTGTACACAAGGTGGTCCGAGACATTCTGCTGATTGGACATAGACAGGCTTTTGCATGGGTTGATGAGTGGTATGA
CATGACAATGGATGAAGTCCGAGAATTTGAACGAGCCACTCAGGAAGCCACCAACAAGAAAATCGGCATTTTCCCACCTGCAATTTCTAT
CTCCAGCATCCCCCTGCTGCCTTCTTCCGTCCGCAGTGCGCCTTCTAGTGCTCCATCCACCCCTCTCTCCACAGACGCACCCGAATTTCT
GTCCGTTCCCAAAGATCGGCCCCGGAAAAAGTCTGCCCCAGAAACTCTCACACTTCCAGACCCTGAGAAAAAAGCCACCCTGAATTTACC
CGGCATGCACTCTTCAGATAAGCCATGTCGGCCCAAATCTGAGTAACTTTATATAAATATCTCATGGGGTTTTATATTTTCATTTGTTGT

>24383_24383_8_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000344537_PITPNC1_chr17_65665624_ENST00000581322_length(amino acids)=164AA_BP=
MREGWRDSHQPIMCSYKLVTVKFEVWGLQTRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDEVREFERATQEATNKKIGIFPPAISI

--------------------------------------------------------------
>24383_24383_9_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000355917_PITPNC1_chr17_65665624_ENST00000299954_length(transcript)=1524nt_BP=227nt
GCGGAAGGGGCTGGGGTTGCGGCGCGGCGGCGAGGACCAGACCGGGGGCGGGGCCGGTAGTGGGAGTGCGGGGCGCGCGGTGACAGCGCG
GGGTTGGCGGCGTGGGACCCAGGGGGCGACAGAGGCAGCAGCAGCCCGAGGCCTGAGGAGAGGAGACCGGCGGCGGCGGCAATGCTGGAG
ACCCTTCGCGAGCGGCTGCTGAGCGTGCAGCAGGATTTCACCTCCGGGATCCTAAGCACTTCAAGTCAGAGAAGACAGGACGGGGACAGT
TGAGGGAAGGCTGGAGAGATAGTCATCAGCCTATCATGTGCTCCTACAAGCTGGTGACTGTGAAGTTTGAGGTCTGGGGGCTTCAGACCA
GAGTGGAACAATTTGTACACAAGGTGGTCCGAGACATTCTGCTGATTGGACATAGACAGGCTTTTGCATGGGTTGATGAGTGGTATGATA
TGACAATGGATGATGTTCGGGAATACGAGAAAAACATGCATGAACAAACCAACATAAAAGTTTGCAATCAGCATTCCTCCCCTGTGGATG
ACATAGAGAGTCATGCCCAAACAAGTACATGACAATGGATGAAGTCCGAGAATTTGAACGAGCCACTCAGGAAGCCACCAACAAGAAAAT
CGGCATTTTCCCACCTGCAATTTCTATCTCCAGCATCCCCCTGCTGCCTTCTTCCGTCCGCAGTGCGCCTTCTAGTGCTCCATCCACCCC
TCTCTCCACAGACGCACCCGAATTTCTGTCCGTTCCCAAAGATCGGCCCCGGAAAAAGTCTGCCCCAGAAACTCTCACACTTCCAGACCC
TGAGAAAAAAGCCACCCTGAATTTACCCGGCATGCACTCTTCAGATAAGCCATGTCGGCCCAAATCTGAGTAACTTTATATAAATATCTC
ATGGGGTTTTATATTTTCATTTGTTGTTGTTGTTTTTTTTTAAGAATCTTCTGATAGAGAAAAAGACTGCTTTGTCACTCAAACATGTTC
CTTCGACCTTTCAGTGTGCATGTGACTCAGTAACTTCACATAGAATATGATTCCCTAAGTATGCTACACAGCATCATATTAGATGTAAGA
TGTAAGACTTGCAAAGGACAGAAGGAATCTTCTGTAACCACATAGCTGTATGCCAGAGAGGAAGCCTTGTTATTGGGCATTTGATGAGGT
TTGGCATGGACTTCAAGGATAAATGAATGAAAACTTTGCACCACTTTTGTTACAAGGTACGGTAGAAAATAGTGAAGTCAGTTTCCTCTC
ATCAAATCTAAAATTCTCCAAAATACTCTCAGGCATAACATACTTAGCTGTTAAATTTTGAACTGCTAATTACTAATACTTGAATACCAA
TAGTTACTGAGATTCCTATTTTGTGGTTAGTCTGACTCAGGATTTGGAGCCTAATTAACTCTAAACTTTTGAAAATTTTAATCATCAAGC

>24383_24383_9_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000355917_PITPNC1_chr17_65665624_ENST00000299954_length(amino acids)=134AA_BP=
MQVGKCRFSCWWLPEWLVQILGLHPLSCTCLGMTLYVIHRGGMLIANFYVGLFMHVFLVFPNIIHCHIIPLINPCKSLSMSNQQNVSDHL

--------------------------------------------------------------
>24383_24383_10_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000355917_PITPNC1_chr17_65665624_ENST00000335257_length(transcript)=1405nt_BP=227nt
GCGGAAGGGGCTGGGGTTGCGGCGCGGCGGCGAGGACCAGACCGGGGGCGGGGCCGGTAGTGGGAGTGCGGGGCGCGCGGTGACAGCGCG
GGGTTGGCGGCGTGGGACCCAGGGGGCGACAGAGGCAGCAGCAGCCCGAGGCCTGAGGAGAGGAGACCGGCGGCGGCGGCAATGCTGGAG
ACCCTTCGCGAGCGGCTGCTGAGCGTGCAGCAGGATTTCACCTCCGGGATCCTAAGCACTTCAAGTCAGAGAAGACAGGACGGGGACAGT
TGAGGGAAGGCTGGAGAGATAGTCATCAGCCTATCATGTGCTCCTACAAGCTGGTGACTGTGAAGTTTGAGGTCTGGGGGCTTCAGACCA
GAGTGGAACAATTTGTACACAAGGTGGTCCGAGACATTCTGCTGATTGGACATAGACAGGCTTTTGCATGGGTTGATGAGTGGTATGACA
TGACAATGGATGAAGTCCGAGAATTTGAACGAGCCACTCAGGAAGCCACCAACAAGAAAATCGGCATTTTCCCACCTGCAATTTCTATCT
CCAGCATCCCCCTGCTGCCTTCTTCCGTCCGCAGTGCGCCTTCTAGTGCTCCATCCACCCCTCTCTCCACAGACGCACCCGAATTTCTGT
CCGTTCCCAAAGATCGGCCCCGGAAAAAGTCTGCCCCAGAAACTCTCACACTTCCAGACCCTGAGAAAAAAGCCACCCTGAATTTACCCG
GCATGCACTCTTCAGATAAGCCATGTCGGCCCAAATCTGAGTAACTTTATATAAATATCTCATGGGGTTTTATATTTTCATTTGTTGTTG
TTGTTTTTTTTTAAGAATCTTCTGATAGAGAAAAAGACTGCTTTGTCACTCAAACATGTTCCTTCGACCTTTCAGTGTGCATGTGACTCA
GTAACTTCACATAGAATATGATTCCCTAAGTATGCTACACAGCATCATATTAGATGTAAGATGTAAGACTTGCAAAGGACAGAAGGAATC
TTCTGTAACCACATAGCTGTATGCCAGAGAGGAAGCCTTGTTATTGGGCATTTGATGAGGTTTGGCATGGACTTCAAGGATAAATGAATG
AAAACTTTGCACCACTTTTGTTACAAGGTACGGTAGAAAATAGTGAAGTCAGTTTCCTCTCATCAAATCTAAAATTCTCCAAAATACTCT
CAGGCATAACATACTTAGCTGTTAAATTTTGAACTGCTAATTACTAATACTTGAATACCAATAGTTACTGAGATTCCTATTTTGTGGTTA
GTCTGACTCAGGATTTGGAGCCTAATTAACTCTAAACTTTTGAAAATTTTAATCATCAAGCTATAGAGGCTCCAAGTGCAATTAATAATA

>24383_24383_10_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000355917_PITPNC1_chr17_65665624_ENST00000335257_length(amino acids)=164AA_BP=
MREGWRDSHQPIMCSYKLVTVKFEVWGLQTRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDEVREFERATQEATNKKIGIFPPAISI

--------------------------------------------------------------
>24383_24383_11_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000355917_PITPNC1_chr17_65665624_ENST00000580974_length(transcript)=5251nt_BP=227nt
GCGGAAGGGGCTGGGGTTGCGGCGCGGCGGCGAGGACCAGACCGGGGGCGGGGCCGGTAGTGGGAGTGCGGGGCGCGCGGTGACAGCGCG
GGGTTGGCGGCGTGGGACCCAGGGGGCGACAGAGGCAGCAGCAGCCCGAGGCCTGAGGAGAGGAGACCGGCGGCGGCGGCAATGCTGGAG
ACCCTTCGCGAGCGGCTGCTGAGCGTGCAGCAGGATTTCACCTCCGGGATCCTAAGCACTTCAAGTCAGAGAAGACAGGACGGGGACAGT
TGAGGGAAGGCTGGAGAGATAGTCATCAGCCTATCATGTGCTCCTACAAGCTGGTGACTGTGAAGTTTGAGGTCTGGGGGCTTCAGACCA
GAGTGGAACAATTTGTACACAAGGTGGTCCGAGACATTCTGCTGATTGGACATAGACAGGCTTTTGCATGGGTTGATGAGTGGTATGATA
TGACAATGGATGATGTTCGGGAATACGAGAAAAACATGCATGAACAAACCAACATAAAAGTTTGCAATCAGCATTCCTCCCCTGTGGATG
ACATAGAGAGTCATGCCCAAACAAGTACATGACAATGGATGAAGTCCGAGAATTTGAACGAGCCACTCAGGAAGCCACCAACAAGAAAAT
CGGCATTTTCCCACCTGCAATTTCTATCTCCAGCATCCCCCTGCTGCCTTCTTCCGTCCGCAGTGCGCCTTCTAGTGCTCCATCCACCCC
TCTCTCCACAGACGCACCCGAATTTCTGTCCGTTCCCAAAGATCGGCCCCGGAAAAAGTCTGCCCCAGAAACTCTCACACTTCCAGACCC
TGAGAAAAAAGCCACCCTGAATTTACCCGGCATGCACTCTTCAGATAAGCCATGTCGGCCCAAATCTGAGTAACTTTATATAAATATCTC
ATGGGGTTTTATATTTTCATTTGTTGTTGTTGTTTTTTTTTAAGAATCTTCTGATAGAGAAAAAGACTGCTTTGTCACTCAAACATGTTC
CTTCGACCTTTCAGTGTGCATGTGACTCAGTAACTTCACATAGAATATGATTCCCTAAGTATGCTACACAGCATCATATTAGATGTAAGA
TGTAAGACTTGCAAAGGACAGAAGGAATCTTCTGTAACCACATAGCTGTATGCCAGAGAGGAAGCCTTGTTATTGGGCATTTGATGAGGT
TTGGCATGGACTTCAAGGATAAATGAATGAAAACTTTGCACCACTTTTGTTACAAGGTACGGTAGAAAATAGTGAAGTCAGTTTCCTCTC
ATCAAATCTAAAATTCTCCAAAATACTCTCAGGCATAACATACTTAGCTGTTAAATTTTGAACTGCTAATTACTAATACTTGAATACCAA
TAGTTACTGAGATTCCTATTTTGTGGTTAGTCTGACTCAGGATTTGGAGCCTAATTAACTCTAAACTTTTGAAAATTTTAATCATCAAGC
TATAGAGGCTCCAAGTGCAATTAATAATAACTCATTTATACCTTCCACAGAATTTAATAAAGATTCTACTTGTTTCTGTCTTTTAATAAC
TTTCCCCTTTTGTGCCCTTGTGGCCTCAGAAATCCTTAAGAATTGCATGGATGAATGTGACCATAACTGATTTTGGAATGGTTCAGTTTA
GGAACCAAGAGGCCCAGGTGAGGCAACATCTTTTTTCTCTACAGGTACCAACAAACCTTGACTTGTCAGCTTCCATCATCAATTAAGATT
CTCAGAATTTGCAATTAATTGAATAGAATTCATTTACTATCTGCCCACTCAAAGAAGTACAAGGGTAGAGTAAGCTAACTGGGCTTTAAC
ATGGTCAGAATGTCTGGTGCATGAACTATAAAAAAGAGAACTGTCTCCCATCCCCTTCCTTGTTTTACTCTTAGTAACATCCAGAATTCC
CTGGAACAGATTGCCTACCACCAGACCTTAGAAAAGACTGTCATTCTCTTGCTCCTTACTTGAAATACAAATATTGGGAATGTCACAGAC
ATCAAGCAACTACTGTCAAGTGGGAGGAGAGAATGAGCAGAATTGCTGACTCCTATTTGTAGAGTGAAAAGGAGGAGTGATAATAGATGC
CCTTCTGTCTAGCTTTCCTTTCTTCAACTAGTGGTAATGCAAGATTAGAATCAAGGTTGACAGGAGGCAAGGTCACTCACTGAAGTGACA
GAAAGACAATTCTCCTTTGCTCCAAAGAGAGAAATCTGTCACCTTTGCACCTCACTGCCTTTAAACACAGACGGGAGGGCAGGCCAAATC
TCAGCATTGACTTTTGTCCTCCAAGAGAGGAAGAGAAGAAGTAATTGGGCAACTTGGAGGCCCACGCCCCAGCTAGCCTTCCTGATCGTA
ACCTCCAACCTCAGGAAAGGGACCTTCCCAAAACACAGATCCCAAAGGAAACAAAATAGACCAAGGAGCATAATCTGCTTCTCTCACACA
GCCTCTCTGCCAGTGGACCCTGCCTGCTTCCCTCTCAGTGCTCAGCACTCTGTGTAGTGTCTTTCAGGTTGATACACTCTCCCAAGGTGC
AGGCGCTGGCCCCATGAGCCCAGCACCAAAGTTTTCTAAGTCATAGGTCAGACTGTCAAGATCATTTCTTTATCTATAGGTTGATATTTA
GCTTAAAAAAAAAGAATAAACCTAGAACTCAAAGGAAACCTGTTGCAAATAGCTTAGATCAACAGTGTATCTCTTCCCTAAGAATGATAG
TATCTTAGTAAGACACCTTCTATGCATGGTATGGAAGCATGATTTTTGCTTGTGGGAAAACCTAATATTTTATCAGACCCCTCGGACTTC
TCAATCCCTCCCTCTCCACACAGTAGTACTTAATGAAAATGTTTTGCTTTAGAGAGCAAAATGCTACTTTCAGAAGACACTGAAATAGTA
TATGTATTTGCTTACCATTTGCAAGCTAAAATCAAGGTGGGATGGGGTCATTATTTTCACATAGAATGTATTTATTTTGTGCAGGCTGTT
AAACACATCTGGCACCTAGTTTTTCCATTAAGAGCATTGCTATTTTCCCTTTTTATAAAGTAGCTTCTGCTGTCAAGGTTAACAATTCTA
TATGCTTTAGGAAGCTAAGTTCTAATTTCCTTTTGTGAGTTTCATTTCTTTTATAACCAGTATGTTACCACAGACATCAGTTGCAAAGCT
ACGATGATAGTGTGATTCTTAGCCGAAAAAAAAGCGTGTGCTCTTAAAGTATGTTCAGTTTTTCTGTCTACATATGCTTTGTGTGAGTTA
AAAAGGGGGTGGGTGGTGTAAATATTCCTTTAGCTGCTTTGCATATTTAACCCAGTCATCAAAAGGCATAAATGACTTCAATATTTTATA
TATCTTGGTTTTCAAGTATCATTTCACATTCTCTATACATGACTTTGTTATTGTGGAATACAAGCCTGCAATGGATGTATATATACAGAA
CATTAATAATTCTTAGAAGGATGGAAGCCAAATGGCTGCATGATGGAAATTAGAAGAAAAAAAAAGCAGAAACTTGAATTTGCTAAGCAT
GTTTGGGGGGAAATAGAATCCTTAACTCAGTGCCTCTGTCTGCGATATGGAAACCTTCAACTTTGTTCACCAAAATTGTATTATACCTGT
GTATATATATATATATATATATATATAAATATAAATATAGTATAGTGAATCAGACACCATCAGTTTTAAGTCTCTGGTAGCCAAACTTAA
ATAAATAATCCATAGAATATCACATACGTTCACTCCATCTTCATCTCTGAAGTTAGTGGAGACCATCAAAATGACTGTACATTTCATAAC
TCTGGGAAGATTTCAAATGTGAAGTGCCCCTGTGCATTTTCTTGGCCATAGCACGGCATTCTTGCTTTAGCTGTGCTTTCCTGGGATGAG
AAGATCTTGGTGTATTTAACACATAAGCTTTGTTAGAAATCACCTCTGAAGATCATTTCATTTTCTCACTTTGGGTTGTTGCAAGACAAA
GCAAAGGAAAAGGAACACAATGAAGGAGGCCGTGACATTTTTAGTTGCCACCGTTGTAACTCAAACAATATGGGTTTGTTGGTGAACTGA
TTTATCAAGGCTTCTGTTACGGTTTTGCATCTGTGTGTGAGGAAAATTTTAATTTATTTGGAAGTATTTATTAGCCATGTTGTTGGTCCT
GAAAATAAATCTCTAAGTAGCACAGTTGTGGGTATATTATGCAGACACTTACCACAATACCTGCAAAAGTAACTGTGGTTTTCTTTCAAG
ACACTGTAATAAACAGTGAACTAAGAGAATAGATTCTGATACATCTCGATAAATCATTCTCTGCAAAAGTTTCAGGGCTAATGTATTTAT
GTGTATTTTTAAATTCTACTTTCTTTGGCATCTCTTCATGGCTCAGCGACAACAAAGTAATAGGTCATTGGCTGGCTTACGTCGATAGGA
ATTTTACTCTTAAGAAGGGCCAGTGTATAGCTGACTCTACATATAATGTGTAATCAGATAATCCAATAGAGAGGAATTGTCCAAATAGTT
TTAGTACCTTTCTGATCATCTGACTCAGTAGGCTAGGAGACAATCTGTCATCTGAGCCATAGTTCTTGAGATTTAAAAAGTCTGTCCAGT
GACTGCAATCTGATTATGAATAAACTATTTTAACTATTCATTCTTGCTGAAACTGAAGTGTACACAATAGCACACTGTTGGCATGCTGAG
GCAAAACATTGGGTTCTTTTGTGTTCTACCTTCAAAACAATCTGTTTGCATTTGAAATATAAGTGTTTAAGCTTTTTAGGAGTTAGTGTA
ATAAGAGAATGTGAATATGTTGGGAAATTTTCAGATGCCATTAATAATTGTAATTTTGTTGTTAAATTAACAAGGACTTTAGGATAAGCC
TCTTGATGTTTTTTGCTTTAAATTGAAAGCATGTCTGTCAAATTGCAAGTCTCCCTTCAGTTTCTATATATCACCCAGGAGAGGGTCTCT
GAGTTGGTGTTGTACCTGTACCACTCACATGTAGCTCAAGTGTAATTTGTAGTGTTTACATTCAAGCTGGGATCTTGATTGGTTAAATTA
ATCCACATACCACTGCCACTGCTGAAGGACCAGGTGTTGGAATACACAGCATTACAGACTATAAGCAAAGCAAACAAAAGTTGATCCTTA
CATATGCCATCCTTCTGTGTCATTTTGTGGCTGTTCTGTGTTTTTCTTCCTAGTTATTTATTATTGTTAATAACTTACTTTTTCTTACAT

>24383_24383_11_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000355917_PITPNC1_chr17_65665624_ENST00000580974_length(amino acids)=134AA_BP=
MQVGKCRFSCWWLPEWLVQILGLHPLSCTCLGMTLYVIHRGGMLIANFYVGLFMHVFLVFPNIIHCHIIPLINPCKSLSMSNQQNVSDHL

--------------------------------------------------------------
>24383_24383_12_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000355917_PITPNC1_chr17_65665624_ENST00000581322_length(transcript)=889nt_BP=227nt
GCGGAAGGGGCTGGGGTTGCGGCGCGGCGGCGAGGACCAGACCGGGGGCGGGGCCGGTAGTGGGAGTGCGGGGCGCGCGGTGACAGCGCG
GGGTTGGCGGCGTGGGACCCAGGGGGCGACAGAGGCAGCAGCAGCCCGAGGCCTGAGGAGAGGAGACCGGCGGCGGCGGCAATGCTGGAG
ACCCTTCGCGAGCGGCTGCTGAGCGTGCAGCAGGATTTCACCTCCGGGATCCTAAGCACTTCAAGTCAGAGAAGACAGGACGGGGACAGT
TGAGGGAAGGCTGGAGAGATAGTCATCAGCCTATCATGTGCTCCTACAAGCTGGTGACTGTGAAGTTTGAGGTCTGGGGGCTTCAGACCA
GAGTGGAACAATTTGTACACAAGGTGGTCCGAGACATTCTGCTGATTGGACATAGACAGGCTTTTGCATGGGTTGATGAGTGGTATGACA
TGACAATGGATGAAGTCCGAGAATTTGAACGAGCCACTCAGGAAGCCACCAACAAGAAAATCGGCATTTTCCCACCTGCAATTTCTATCT
CCAGCATCCCCCTGCTGCCTTCTTCCGTCCGCAGTGCGCCTTCTAGTGCTCCATCCACCCCTCTCTCCACAGACGCACCCGAATTTCTGT
CCGTTCCCAAAGATCGGCCCCGGAAAAAGTCTGCCCCAGAAACTCTCACACTTCCAGACCCTGAGAAAAAAGCCACCCTGAATTTACCCG
GCATGCACTCTTCAGATAAGCCATGTCGGCCCAAATCTGAGTAACTTTATATAAATATCTCATGGGGTTTTATATTTTCATTTGTTGTTG

>24383_24383_12_DTNBP1-PITPNC1_DTNBP1_chr6_15663045_ENST00000355917_PITPNC1_chr17_65665624_ENST00000581322_length(amino acids)=164AA_BP=
MREGWRDSHQPIMCSYKLVTVKFEVWGLQTRVEQFVHKVVRDILLIGHRQAFAWVDEWYDMTMDEVREFERATQEATNKKIGIFPPAISI

--------------------------------------------------------------

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Fusion Gene PPI Analysis for DTNBP1-PITPNC1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DTNBP1-PITPNC1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DTNBP1-PITPNC1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource