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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:DYNC1I1-ASB4 (FusionGDB2 ID:24610)

Fusion Gene Summary for DYNC1I1-ASB4

check button Fusion gene summary
Fusion gene informationFusion gene name: DYNC1I1-ASB4
Fusion gene ID: 24610
HgeneTgene
Gene symbol

DYNC1I1

ASB4

Gene ID

1780

51666

Gene namedynein cytoplasmic 1 intermediate chain 1ankyrin repeat and SOCS box containing 4
SynonymsDNCI1|DNCIC1ASB-4
Cytomap

7q21.3

7q21.3

Type of geneprotein-codingprotein-coding
Descriptioncytoplasmic dynein 1 intermediate chain 1DH IC-1cytoplasmic dynein intermediate chain 1dynein intermediate chain 1, cytosolicdynein, cytoplasmic, intermediate polypeptide 1ankyrin repeat and SOCS box protein 4
Modification date2020031320200313
UniProtAcc

O14576

Q9Y574

Ensembl transtripts involved in fusion geneENST00000324972, ENST00000359388, 
ENST00000437599, ENST00000447467, 
ENST00000457059, ENST00000537881, 
ENST00000413338, ENST00000497626, 
ENST00000257621, ENST00000428113, 
ENST00000325885, 
Fusion gene scores* DoF score6 X 5 X 6=1803 X 3 X 3=27
# samples 73
** MAII scorelog2(7/180*10)=-1.36257007938471
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: DYNC1I1 [Title/Abstract] AND ASB4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointASB4(95165862)-DYNC1I1(95434033), # samples:3
DYNC1I1(95499310)-ASB4(95125070), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across DYNC1I1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ASB4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4ACCTCGA-OR-A5J1-01ADYNC1I1chr7

95499310

-ASB4chr7

95125070

+
ChimerDB4ACCTCGA-OR-A5J1-01ADYNC1I1chr7

95499310

+ASB4chr7

95125070

+


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Fusion Gene ORF analysis for DYNC1I1-ASB4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000324972ENST00000257621DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
5CDS-3UTRENST00000324972ENST00000428113DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
5CDS-3UTRENST00000359388ENST00000257621DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
5CDS-3UTRENST00000359388ENST00000428113DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
5CDS-3UTRENST00000437599ENST00000257621DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
5CDS-3UTRENST00000437599ENST00000428113DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
5CDS-3UTRENST00000447467ENST00000257621DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
5CDS-3UTRENST00000447467ENST00000428113DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
5CDS-3UTRENST00000457059ENST00000257621DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
5CDS-3UTRENST00000457059ENST00000428113DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
5CDS-3UTRENST00000537881ENST00000257621DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
5CDS-3UTRENST00000537881ENST00000428113DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
In-frameENST00000324972ENST00000325885DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
In-frameENST00000359388ENST00000325885DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
In-frameENST00000437599ENST00000325885DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
In-frameENST00000447467ENST00000325885DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
In-frameENST00000457059ENST00000325885DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
In-frameENST00000537881ENST00000325885DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
intron-3CDSENST00000413338ENST00000325885DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
intron-3CDSENST00000497626ENST00000325885DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
intron-3UTRENST00000413338ENST00000257621DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
intron-3UTRENST00000413338ENST00000428113DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
intron-3UTRENST00000497626ENST00000257621DYNC1I1chr7

95499310

+ASB4chr7

95125070

+
intron-3UTRENST00000497626ENST00000428113DYNC1I1chr7

95499310

+ASB4chr7

95125070

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000447467DYNC1I1chr795499310+ENST00000325885ASB4chr795125070+42867191541812552
ENST00000324972DYNC1I1chr795499310+ENST00000325885ASB4chr795125070+43017341181827569
ENST00000537881DYNC1I1chr795499310+ENST00000325885ASB4chr795125070+41866191141712532
ENST00000437599DYNC1I1chr795499310+ENST00000325885ASB4chr795125070+42346671111760549
ENST00000359388DYNC1I1chr795499310+ENST00000325885ASB4chr795125070+41826151101708532
ENST00000457059DYNC1I1chr795499310+ENST00000325885ASB4chr795125070+4157590731683536

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000447467ENST00000325885DYNC1I1chr795499310+ASB4chr795125070+0.0006559390.99934405
ENST00000324972ENST00000325885DYNC1I1chr795499310+ASB4chr795125070+0.0005107010.9994893
ENST00000537881ENST00000325885DYNC1I1chr795499310+ASB4chr795125070+0.0004850650.99951494
ENST00000437599ENST00000325885DYNC1I1chr795499310+ASB4chr795125070+0.0004426440.9995573
ENST00000359388ENST00000325885DYNC1I1chr795499310+ASB4chr795125070+0.0004807740.9995192
ENST00000457059ENST00000325885DYNC1I1chr795499310+ASB4chr795125070+0.0007548310.99924517

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Fusion Genomic Features for DYNC1I1-ASB4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
DYNC1I1chr795499310+ASB4chr795125069+0.0566536230.94334644
DYNC1I1chr795499310+ASB4chr795125069+0.0566536230.94334644

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for DYNC1I1-ASB4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:95165862/chr7:95434033)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
DYNC1I1

O14576

ASB4

Q9Y574

FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCTN1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kinetochores.FUNCTION: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes differentiation and maturation of the vascular lineage by an oxygen-dependent mechanism (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneASB4chr7:95499310chr7:95125070ENST0000032588505371_42362427.0DomainSOCS box
TgeneASB4chr7:95499310chr7:95125070ENST0000042811303371_42362350.0DomainSOCS box
TgeneASB4chr7:95499310chr7:95125070ENST0000032588505106_13562427.0RepeatNote=ANK 2
TgeneASB4chr7:95499310chr7:95125070ENST0000032588505139_16862427.0RepeatNote=ANK 3
TgeneASB4chr7:95499310chr7:95125070ENST0000032588505174_20362427.0RepeatNote=ANK 4
TgeneASB4chr7:95499310chr7:95125070ENST0000032588505207_24762427.0RepeatNote=ANK 5
TgeneASB4chr7:95499310chr7:95125070ENST0000032588505251_28062427.0RepeatNote=ANK 6
TgeneASB4chr7:95499310chr7:95125070ENST000003258850574_10362427.0RepeatNote=ANK 1
TgeneASB4chr7:95499310chr7:95125070ENST0000042811303106_13562350.0RepeatNote=ANK 2
TgeneASB4chr7:95499310chr7:95125070ENST0000042811303139_16862350.0RepeatNote=ANK 3
TgeneASB4chr7:95499310chr7:95125070ENST0000042811303174_20362350.0RepeatNote=ANK 4
TgeneASB4chr7:95499310chr7:95125070ENST0000042811303207_24762350.0RepeatNote=ANK 5
TgeneASB4chr7:95499310chr7:95125070ENST0000042811303251_28062350.0RepeatNote=ANK 6
TgeneASB4chr7:95499310chr7:95125070ENST000004281130374_10362350.0RepeatNote=ANK 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000324972+617285_334180646.0RepeatNote=WD 1
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000324972+617338_378180646.0RepeatNote=WD 2
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000324972+617387_428180646.0RepeatNote=WD 3
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000324972+617437_477180646.0RepeatNote=WD 4
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000324972+617482_527180646.0RepeatNote=WD 5
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000324972+617530_570180646.0RepeatNote=WD 6
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000324972+617576_615180646.0RepeatNote=WD 7
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000359388+516285_334143609.0RepeatNote=WD 1
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000359388+516338_378143609.0RepeatNote=WD 2
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000359388+516387_428143609.0RepeatNote=WD 3
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000359388+516437_477143609.0RepeatNote=WD 4
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000359388+516482_527143609.0RepeatNote=WD 5
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000359388+516530_570143609.0RepeatNote=WD 6
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000359388+516576_615143609.0RepeatNote=WD 7
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000447467+617285_334163629.0RepeatNote=WD 1
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000447467+617338_378163629.0RepeatNote=WD 2
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000447467+617387_428163629.0RepeatNote=WD 3
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000447467+617437_477163629.0RepeatNote=WD 4
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000447467+617482_527163629.0RepeatNote=WD 5
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000447467+617530_570163629.0RepeatNote=WD 6
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000447467+617576_615163629.0RepeatNote=WD 7
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000457059+617285_334163629.0RepeatNote=WD 1
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000457059+617338_378163629.0RepeatNote=WD 2
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000457059+617387_428163629.0RepeatNote=WD 3
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000457059+617437_477163629.0RepeatNote=WD 4
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000457059+617482_527163629.0RepeatNote=WD 5
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000457059+617530_570163629.0RepeatNote=WD 6
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000457059+617576_615163629.0RepeatNote=WD 7


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Fusion Gene Sequence for DYNC1I1-ASB4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>24610_24610_1_DYNC1I1-ASB4_DYNC1I1_chr7_95499310_ENST00000324972_ASB4_chr7_95125070_ENST00000325885_length(transcript)=4301nt_BP=734nt
CTGGGAGAGAGGAAGTGATCGCTCCCGGAGGAGCGCGAGCCGAGCGGCCGGCGCAGCGTGAGACAGCACATCCTGCCCGCGCCGGCCCCG
CCACCTTCGGGAGCCGCCTGCACCAACGCTGCCGCCGCCCAGGAGCCGCCGCCGGCTCGGGGAGCCCAGTTCCGCCGCTGCCGAGCGCGT
CCAGGAAACCAACATGTCTGACAAAAGTGACTTAAAAGCTGAGCTAGAGCGCAAAAAGCAGCGCTTAGCACAGATAAGAGAAGAGAAGAA
ACGGAAGGAAGAGGAGAGGAAAAAGAAAGAGGCTGATATGCAGCAGAAGAAAGAACCCGTTCAGGACGACTCTGATCTGGATCGCAAACG
ACGAGAGACAGAGGCTTTGCTGCAAAGCATTGGTATCTCACCGGAGCCGCCTCTAGTGCAGCCGCTGCATTTTTTAACATGGGATACCTG
TTATTTTCATTATTTAGTCCCAACCCCTATGTCTCCCTCCTCGAAATCAGTGAGCACTCCCAGTGAAGCTGGAAGCCAAGACTCAGGCGA
TCTGGGGCCATTAACAAGGACCCTGCAGTGGGACACAGACCCCTCAGTGCTCCAGCTGCAGTCAGACTCAGAACTTGGAAGAAGACTGCA
TAAACTGGGCGTGTCAAAGGTCACCCAAGTGGATTTCCTGCCAAGGGAAGTAGTGTCCTACTCAAAGGAGACCCAGACTCCTCTTGCCAC
GCATCAGTCTGAAGGTTACTGGTTGCCTAGCTATAAATTGAAGTCTTCCTGGGCCACAGGCCTCCATCTCTCTGTCTTGTTTGGCCATGT
GGAATGTCTTCTGGTGCTACTGGACCACAATGCTACAATCAACTGTAGACCCAATGGGAAAACCCCTCTTCACGTGGCTTGTGAAATGGC
CAATGTGGATTGTGTTAAGATCCTCTGTGATCGTGGGGCAAAGCTCAATTGCTACTCCTTAAGTGGACACACAGCTTTGCACTTTTGTAC
AACTCCAAGTTCCATTCTCTGTGCCAAGCAATTGGTTTGGAGAGGGGCGAATGTGAACATGAAGACCAACAACCAAGATGAGGAGACGCC
CTTGCACACGGCTGCCCACTTCGGCCTTTCGGAGCTGGTGGCCTTCTACGTGGAACACGGGGCCATAGTGGACAGCGTGAATGCCCACAT
GGAGACCCCCCTGGCCATCGCCGCCTACTGGGCCCTCCGCTTTAAGGAGCAGGAGTACAGCACGGAGCACCACCTGGTCTGCCGCATGCT
GCTTGACTACAAAGCCGAAGTCAATGCCCGAGATGACGACTTTAAATCTCCCCTCCACAAGGCAGCCTGGAACTGTGACCACGTGCTCAT
GCACATGATGCTGGAAGCTGGCGCCGAAGCCAATCTCATGGATATCAACGGCTGTGCTGCCATCCAGTACGTGCTGAAGGTCACCTCCGT
GCGCCCTGCTGCCCAGCCTGAGATCTGCTACCAGCTCCTGTTGAACCATGGGGCTGCCCGAATATACCCTCCACAGTTCCATAAGGTGAT
ACAGGCCTGCCATTCTTGTCCTAAAGCAATTGAAGTTGTAGTCAATGCCTATGAACACATCAGATGGAACACAAAGTGGAGAAGAGCTAT
CCCCGATGATGACTTGGAGAAATACTGGGATTTTTACCACTCTCTCTTTACTGTGTGCTGTAACTCTCCAAGGACTCTCATGCACTTATC
GAGATGTGCCATTAGAAGAACATTACACAACAGATGCCATAGAGCAATTCCTTTGCTTTCCCTCCCATTGTCATTGAAAAAGTACTTGCT
TTTAGAGCCAGAGGGAATTATTTATTAAGCCTTATGAGACAGCAGTTCCCAATCCTAGGTATTTAAGTGGACTTGCTGGGTAGACACAGT
TTGCCTAAATAAAATGGTACTTGGGTTGATTATAACACTTCAGGGATTTCAAAACACTTTACAAACACTGCCATTAATCCTAGAATATCA
TGGTATGGGGAAATAAAGAAGAAGTAAAGTTAAGGAATTTTCAAAGACAAGGATGTATTCAGAATGTACTGATAGAACAGTAATAACTAA
TATGTATAGTGTTCTTACTAAGTACCTGAAATATTTTTGTAAAACTTCTTATATCTTATCTCATCTGAAATGGGACCCAGGTTTTCTTCC
AACCAATATAATTCTGTGCCTTATCAGTAATATGTTTACATTCTCATTCAAATGGCCATATAGCAGGCTTTGCAATTGGCCTCTTAAACT
TGGTGTTTTCCCCCATTACCCCTTAGCAGTAATTACTGTCACTAGTTTTGCAAACTCCTACTCCCCAAACCAAGCTACTCAAGTTTATTT
CAGTGATGAAGGCATATGAGCATAGTCAAAACAAGGAGATCTTGGAGTCAAATTAGAAATGAGAAAGAAACATCAGTCCAGTTAATAGTC
AAGAATGGACATTTGAACCAGACATCACTGAGCCAGAGACTGGAGATGCAAAGATGAGTCCCATGTGACTCCTGCCTTCCAGGATCTCAC
CATTTAGCAGAGGATCCAGACATACACACAGCTAACTGCAATATAAAGTGATGGGGCAAGAGTACAGGTGCAGACTCACTTTTAATGCTT
ATCTTTCAAAGTTGTGTTTCTGACATGAAGTGTGATTTTTCTTTTAAGCATGAAGTTAAAGAGTGAAGGGGTTATGTAAAGTAGAGGGAT
CTCCTGCTCTTGTTAGGGTATTTTTAAGGTTTTTTCTAGATAGTGTGTCTTTTTGGTATGGTTTCTTGGTTAGTATTAATACTTTCCCAG
ACTCCTTGAGAAAAATATTGCACACTCAATGGCTCCAGTGCATGTGACAAGGAAGCATAGGAAAATGGGGGAAAGAAAGTGTGTGAGGGG
ACCTAGTTGATTACTTCGGTCTTTTTATGTAGCAGACTGACATTTCATAGCATTGTAGCTAAGAGATAAGGAGCACTTTGCTAGTGACAG
TGGGCTACGAAAAGTAAATAGAGAGACTTTTTGAAAATGGTAAAAGTTTGAGAAACTTGGGAAGATTAGTGTGTTAATCAGGCTTGCTAG
TTAGTGGATTGCAGAAAGAAAAATGTAGGTGATTAAGCTCTGGGCCTTGTGGTTTATGAGGTCAATTTTGCTTCACTTTTTTTTTTGTTC
TTGCTATAATCACTTTTAGATAAGCTCATTGCTCTTAGCATCATTTTTTAGAGGTTAAAGCAGAAGTAAATTGCAAACAAATCTGTCAGT
TGTGAGCAGATTTCTTTTATGTGTGTGGTTCTCCATCATATTTAACTTTGGATGCTGGAGTGTTGAATAGAGATGATGTCAGATATTCCA
ATAGGCTATCATTTAATGTTAACTGGCAATCACCTAACTGGTTAATCTCAGTTGAGACTGTGCTTCTGAACTGGGATTGTCTTACTCCCA
GGGCTGTGTAAGAAAAGTCATAGGTGGATACAATAATCTCTTTTAAGTATCAGTTTTACTCAGATATTTTGGTGGAGATATTTTGTACTA
AAACAAGATCTATATCATGGAATAGAATGCTGAATTTGTATGAATTATTCACATAAAGCTTGATCTTTCAAAAAATAGTTTGCTTGCAGC
AAGTGGTATTAGAACACATCCTAAAACAGAATGAAATGATGTCTTTTGCAGCAACTTGGATGGAGCTGGAGGCCATTATTCTAAGTGAAG
TAACTCAGGAATGGAAAGTGAAATACCATATGTTCTCACTTATAAGTGGGAGCTAAGCAATGAGGATGCAAAGACATCCAGAGTGATATA
ATGGACTATGGGGACTTGCAAGGGGAAGCTTGAGAGTGGGGTGAGGGATAAAAGACTACATATTGGGTACAGTGTACACTGCTCCAGTGA
TGGGTGCACTAAAATCTCAAAATTCACCACTAAAGAATGTATCCATGTAACCAAAAACCACCTGTACCCCCAAAACTATTGAAATCTTAA
AATAGTAATAATTAACAAAGTAAAACAAGATCACACCCTGGAACAATTGGAGGATTGCTTGCTGCCCTGCATCTTAAGGCGTATTCTAGC
AGCAAAGCTTGTGATGCACTGACTTGGGGCAAGTAAAACTGATGCTGAGGACAAAGGGAGAAGATGTTCCTCGCCCAGGGAAATGAAAAC
TTTTCTTATTCACCTTGCTTGTGCTTAAACACTTATGTTCATCTAGTGTAGAATACATGGCTACTTGTTTGTAATTTTTTTATTGGTGGA

>24610_24610_1_DYNC1I1-ASB4_DYNC1I1_chr7_95499310_ENST00000324972_ASB4_chr7_95125070_ENST00000325885_length(amino acids)=569AA_BP=205
MPPPRSRRRLGEPSSAAAERVQETNMSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQS
IGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQ
VDFLPREVVSYSKETQTPLATHQSEGYWLPSYKLKSSWATGLHLSVLFGHVECLLVLLDHNATINCRPNGKTPLHVACEMANVDCVKILC
DRGAKLNCYSLSGHTALHFCTTPSSILCAKQLVWRGANVNMKTNNQDEETPLHTAAHFGLSELVAFYVEHGAIVDSVNAHMETPLAIAAY
WALRFKEQEYSTEHHLVCRMLLDYKAEVNARDDDFKSPLHKAAWNCDHVLMHMMLEAGAEANLMDINGCAAIQYVLKVTSVRPAAQPEIC
YQLLLNHGAARIYPPQFHKVIQACHSCPKAIEVVVNAYEHIRWNTKWRRAIPDDDLEKYWDFYHSLFTVCCNSPRTLMHLSRCAIRRTLH

--------------------------------------------------------------
>24610_24610_2_DYNC1I1-ASB4_DYNC1I1_chr7_95499310_ENST00000359388_ASB4_chr7_95125070_ENST00000325885_length(transcript)=4182nt_BP=615nt
GAGGAAGTGATCGCTCCCGGAGGAGCGCGAGCCGAGCGGCCGGCGCAGCGTGAGACAGCACATCCTGCCCGCGCCGGCCCCGCCACCTTC
GGGAGCCGCCTGCACCAACGCTGCCGCCGCCCAGGAGCCGCCGCCGGCTCGGGGAGCCCAGTTCCGCCGCTGCCGAGCGCGTCCAGGAAA
CCAACATGTCTGACAAAAGTGACTTAAAAGCTGAGCTAGAGCGCAAAAAGCAGCGCTTAGCACAGATAAGAGAAGAGAAGAAACGGAAGG
AAGAGGAGAGGAAAAAGAAAGAGGCTGATATGCAGCAGAAGAAAGAACCCGTTCAGGACGACTCTGATCTGGATCGCAAACGACGAGAGA
CAGAGGCTTTGCTGCAAAGCATTGGTATCTCACCGGAGCCGCCTCTAGTCCCAACCCCTATGTCTCCCTCCTCGAAATCAGTGAGCACTC
CCAGTGAAGCTGGAAGCCAAGACTCAGGCGATCTGGGGCCATTAACAAGAAGAAGACTGCATAAACTGGGCGTGTCAAAGGTCACCCAAG
TGGATTTCCTGCCAAGGGAAGTAGTGTCCTACTCAAAGGAGACCCAGACTCCTCTTGCCACGCATCAGTCTGAAGGTTACTGGTTGCCTA
GCTATAAATTGAAGTCTTCCTGGGCCACAGGCCTCCATCTCTCTGTCTTGTTTGGCCATGTGGAATGTCTTCTGGTGCTACTGGACCACA
ATGCTACAATCAACTGTAGACCCAATGGGAAAACCCCTCTTCACGTGGCTTGTGAAATGGCCAATGTGGATTGTGTTAAGATCCTCTGTG
ATCGTGGGGCAAAGCTCAATTGCTACTCCTTAAGTGGACACACAGCTTTGCACTTTTGTACAACTCCAAGTTCCATTCTCTGTGCCAAGC
AATTGGTTTGGAGAGGGGCGAATGTGAACATGAAGACCAACAACCAAGATGAGGAGACGCCCTTGCACACGGCTGCCCACTTCGGCCTTT
CGGAGCTGGTGGCCTTCTACGTGGAACACGGGGCCATAGTGGACAGCGTGAATGCCCACATGGAGACCCCCCTGGCCATCGCCGCCTACT
GGGCCCTCCGCTTTAAGGAGCAGGAGTACAGCACGGAGCACCACCTGGTCTGCCGCATGCTGCTTGACTACAAAGCCGAAGTCAATGCCC
GAGATGACGACTTTAAATCTCCCCTCCACAAGGCAGCCTGGAACTGTGACCACGTGCTCATGCACATGATGCTGGAAGCTGGCGCCGAAG
CCAATCTCATGGATATCAACGGCTGTGCTGCCATCCAGTACGTGCTGAAGGTCACCTCCGTGCGCCCTGCTGCCCAGCCTGAGATCTGCT
ACCAGCTCCTGTTGAACCATGGGGCTGCCCGAATATACCCTCCACAGTTCCATAAGGTGATACAGGCCTGCCATTCTTGTCCTAAAGCAA
TTGAAGTTGTAGTCAATGCCTATGAACACATCAGATGGAACACAAAGTGGAGAAGAGCTATCCCCGATGATGACTTGGAGAAATACTGGG
ATTTTTACCACTCTCTCTTTACTGTGTGCTGTAACTCTCCAAGGACTCTCATGCACTTATCGAGATGTGCCATTAGAAGAACATTACACA
ACAGATGCCATAGAGCAATTCCTTTGCTTTCCCTCCCATTGTCATTGAAAAAGTACTTGCTTTTAGAGCCAGAGGGAATTATTTATTAAG
CCTTATGAGACAGCAGTTCCCAATCCTAGGTATTTAAGTGGACTTGCTGGGTAGACACAGTTTGCCTAAATAAAATGGTACTTGGGTTGA
TTATAACACTTCAGGGATTTCAAAACACTTTACAAACACTGCCATTAATCCTAGAATATCATGGTATGGGGAAATAAAGAAGAAGTAAAG
TTAAGGAATTTTCAAAGACAAGGATGTATTCAGAATGTACTGATAGAACAGTAATAACTAATATGTATAGTGTTCTTACTAAGTACCTGA
AATATTTTTGTAAAACTTCTTATATCTTATCTCATCTGAAATGGGACCCAGGTTTTCTTCCAACCAATATAATTCTGTGCCTTATCAGTA
ATATGTTTACATTCTCATTCAAATGGCCATATAGCAGGCTTTGCAATTGGCCTCTTAAACTTGGTGTTTTCCCCCATTACCCCTTAGCAG
TAATTACTGTCACTAGTTTTGCAAACTCCTACTCCCCAAACCAAGCTACTCAAGTTTATTTCAGTGATGAAGGCATATGAGCATAGTCAA
AACAAGGAGATCTTGGAGTCAAATTAGAAATGAGAAAGAAACATCAGTCCAGTTAATAGTCAAGAATGGACATTTGAACCAGACATCACT
GAGCCAGAGACTGGAGATGCAAAGATGAGTCCCATGTGACTCCTGCCTTCCAGGATCTCACCATTTAGCAGAGGATCCAGACATACACAC
AGCTAACTGCAATATAAAGTGATGGGGCAAGAGTACAGGTGCAGACTCACTTTTAATGCTTATCTTTCAAAGTTGTGTTTCTGACATGAA
GTGTGATTTTTCTTTTAAGCATGAAGTTAAAGAGTGAAGGGGTTATGTAAAGTAGAGGGATCTCCTGCTCTTGTTAGGGTATTTTTAAGG
TTTTTTCTAGATAGTGTGTCTTTTTGGTATGGTTTCTTGGTTAGTATTAATACTTTCCCAGACTCCTTGAGAAAAATATTGCACACTCAA
TGGCTCCAGTGCATGTGACAAGGAAGCATAGGAAAATGGGGGAAAGAAAGTGTGTGAGGGGACCTAGTTGATTACTTCGGTCTTTTTATG
TAGCAGACTGACATTTCATAGCATTGTAGCTAAGAGATAAGGAGCACTTTGCTAGTGACAGTGGGCTACGAAAAGTAAATAGAGAGACTT
TTTGAAAATGGTAAAAGTTTGAGAAACTTGGGAAGATTAGTGTGTTAATCAGGCTTGCTAGTTAGTGGATTGCAGAAAGAAAAATGTAGG
TGATTAAGCTCTGGGCCTTGTGGTTTATGAGGTCAATTTTGCTTCACTTTTTTTTTTGTTCTTGCTATAATCACTTTTAGATAAGCTCAT
TGCTCTTAGCATCATTTTTTAGAGGTTAAAGCAGAAGTAAATTGCAAACAAATCTGTCAGTTGTGAGCAGATTTCTTTTATGTGTGTGGT
TCTCCATCATATTTAACTTTGGATGCTGGAGTGTTGAATAGAGATGATGTCAGATATTCCAATAGGCTATCATTTAATGTTAACTGGCAA
TCACCTAACTGGTTAATCTCAGTTGAGACTGTGCTTCTGAACTGGGATTGTCTTACTCCCAGGGCTGTGTAAGAAAAGTCATAGGTGGAT
ACAATAATCTCTTTTAAGTATCAGTTTTACTCAGATATTTTGGTGGAGATATTTTGTACTAAAACAAGATCTATATCATGGAATAGAATG
CTGAATTTGTATGAATTATTCACATAAAGCTTGATCTTTCAAAAAATAGTTTGCTTGCAGCAAGTGGTATTAGAACACATCCTAAAACAG
AATGAAATGATGTCTTTTGCAGCAACTTGGATGGAGCTGGAGGCCATTATTCTAAGTGAAGTAACTCAGGAATGGAAAGTGAAATACCAT
ATGTTCTCACTTATAAGTGGGAGCTAAGCAATGAGGATGCAAAGACATCCAGAGTGATATAATGGACTATGGGGACTTGCAAGGGGAAGC
TTGAGAGTGGGGTGAGGGATAAAAGACTACATATTGGGTACAGTGTACACTGCTCCAGTGATGGGTGCACTAAAATCTCAAAATTCACCA
CTAAAGAATGTATCCATGTAACCAAAAACCACCTGTACCCCCAAAACTATTGAAATCTTAAAATAGTAATAATTAACAAAGTAAAACAAG
ATCACACCCTGGAACAATTGGAGGATTGCTTGCTGCCCTGCATCTTAAGGCGTATTCTAGCAGCAAAGCTTGTGATGCACTGACTTGGGG
CAAGTAAAACTGATGCTGAGGACAAAGGGAGAAGATGTTCCTCGCCCAGGGAAATGAAAACTTTTCTTATTCACCTTGCTTGTGCTTAAA
CACTTATGTTCATCTAGTGTAGAATACATGGCTACTTGTTTGTAATTTTTTTATTGGTGGAATTAAAGTAATTTTTCCTTATCTTTGAAC

>24610_24610_2_DYNC1I1-ASB4_DYNC1I1_chr7_95499310_ENST00000359388_ASB4_chr7_95125070_ENST00000325885_length(amino acids)=532AA_BP=168
MPPPRSRRRLGEPSSAAAERVQETNMSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQS
IGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEGYWLPSYKLKSS
WATGLHLSVLFGHVECLLVLLDHNATINCRPNGKTPLHVACEMANVDCVKILCDRGAKLNCYSLSGHTALHFCTTPSSILCAKQLVWRGA
NVNMKTNNQDEETPLHTAAHFGLSELVAFYVEHGAIVDSVNAHMETPLAIAAYWALRFKEQEYSTEHHLVCRMLLDYKAEVNARDDDFKS
PLHKAAWNCDHVLMHMMLEAGAEANLMDINGCAAIQYVLKVTSVRPAAQPEICYQLLLNHGAARIYPPQFHKVIQACHSCPKAIEVVVNA

--------------------------------------------------------------
>24610_24610_3_DYNC1I1-ASB4_DYNC1I1_chr7_95499310_ENST00000437599_ASB4_chr7_95125070_ENST00000325885_length(transcript)=4234nt_BP=667nt
AGAGGAAGTGATCGCTCCCGGAGGAGCGCGAGCCGAGCGGCCGGCGCAGCGTGAGACAGCACATCCTGCCCGCGCCGGCCCCGCCACCTT
CGGGAGCCGCCTGCACCAACGCTGCCGCCGCCCAGGAGCCGCCGCCGGCTCGGGGAGCCCAGTTCCGCCGCTGCCGAGCGCGTCCAGGAA
ACCAACATGTCTGACAAAAGTGACTTAAAAGCTGAGCTAGAGCGCAAAAAGCAGCGCTTAGCACAGATAAGAGAAGAGAAGAAACGGAAG
GAAGAGGAGAGGAAAAAGAAAGAGGCTGATATGCAGCAGAAGAAAGAACCCGTTCAGGACGACTCTGATCTGGATCGCAAACGACGAGAG
ACAGAGGCTTTGCTGCAAAGCATTGGTATCTCACCGGAGCCGCCTCTAGTGCAGCCGCTGCATTTTTTAACATGGGATACCTGTTATTTT
CATTATTTAGTCCCAACCCCTATGTCTCCCTCCTCGAAATCAGTGAGCACTCCCAGTGAAGCTGGAAGCCAAGACTCAGGCGATCTGGGG
CCATTAACAAGAAGAAGACTGCATAAACTGGGCGTGTCAAAGGTCACCCAAGTGGATTTCCTGCCAAGGGAAGTAGTGTCCTACTCAAAG
GAGACCCAGACTCCTCTTGCCACGCATCAGTCTGAAGGTTACTGGTTGCCTAGCTATAAATTGAAGTCTTCCTGGGCCACAGGCCTCCAT
CTCTCTGTCTTGTTTGGCCATGTGGAATGTCTTCTGGTGCTACTGGACCACAATGCTACAATCAACTGTAGACCCAATGGGAAAACCCCT
CTTCACGTGGCTTGTGAAATGGCCAATGTGGATTGTGTTAAGATCCTCTGTGATCGTGGGGCAAAGCTCAATTGCTACTCCTTAAGTGGA
CACACAGCTTTGCACTTTTGTACAACTCCAAGTTCCATTCTCTGTGCCAAGCAATTGGTTTGGAGAGGGGCGAATGTGAACATGAAGACC
AACAACCAAGATGAGGAGACGCCCTTGCACACGGCTGCCCACTTCGGCCTTTCGGAGCTGGTGGCCTTCTACGTGGAACACGGGGCCATA
GTGGACAGCGTGAATGCCCACATGGAGACCCCCCTGGCCATCGCCGCCTACTGGGCCCTCCGCTTTAAGGAGCAGGAGTACAGCACGGAG
CACCACCTGGTCTGCCGCATGCTGCTTGACTACAAAGCCGAAGTCAATGCCCGAGATGACGACTTTAAATCTCCCCTCCACAAGGCAGCC
TGGAACTGTGACCACGTGCTCATGCACATGATGCTGGAAGCTGGCGCCGAAGCCAATCTCATGGATATCAACGGCTGTGCTGCCATCCAG
TACGTGCTGAAGGTCACCTCCGTGCGCCCTGCTGCCCAGCCTGAGATCTGCTACCAGCTCCTGTTGAACCATGGGGCTGCCCGAATATAC
CCTCCACAGTTCCATAAGGTGATACAGGCCTGCCATTCTTGTCCTAAAGCAATTGAAGTTGTAGTCAATGCCTATGAACACATCAGATGG
AACACAAAGTGGAGAAGAGCTATCCCCGATGATGACTTGGAGAAATACTGGGATTTTTACCACTCTCTCTTTACTGTGTGCTGTAACTCT
CCAAGGACTCTCATGCACTTATCGAGATGTGCCATTAGAAGAACATTACACAACAGATGCCATAGAGCAATTCCTTTGCTTTCCCTCCCA
TTGTCATTGAAAAAGTACTTGCTTTTAGAGCCAGAGGGAATTATTTATTAAGCCTTATGAGACAGCAGTTCCCAATCCTAGGTATTTAAG
TGGACTTGCTGGGTAGACACAGTTTGCCTAAATAAAATGGTACTTGGGTTGATTATAACACTTCAGGGATTTCAAAACACTTTACAAACA
CTGCCATTAATCCTAGAATATCATGGTATGGGGAAATAAAGAAGAAGTAAAGTTAAGGAATTTTCAAAGACAAGGATGTATTCAGAATGT
ACTGATAGAACAGTAATAACTAATATGTATAGTGTTCTTACTAAGTACCTGAAATATTTTTGTAAAACTTCTTATATCTTATCTCATCTG
AAATGGGACCCAGGTTTTCTTCCAACCAATATAATTCTGTGCCTTATCAGTAATATGTTTACATTCTCATTCAAATGGCCATATAGCAGG
CTTTGCAATTGGCCTCTTAAACTTGGTGTTTTCCCCCATTACCCCTTAGCAGTAATTACTGTCACTAGTTTTGCAAACTCCTACTCCCCA
AACCAAGCTACTCAAGTTTATTTCAGTGATGAAGGCATATGAGCATAGTCAAAACAAGGAGATCTTGGAGTCAAATTAGAAATGAGAAAG
AAACATCAGTCCAGTTAATAGTCAAGAATGGACATTTGAACCAGACATCACTGAGCCAGAGACTGGAGATGCAAAGATGAGTCCCATGTG
ACTCCTGCCTTCCAGGATCTCACCATTTAGCAGAGGATCCAGACATACACACAGCTAACTGCAATATAAAGTGATGGGGCAAGAGTACAG
GTGCAGACTCACTTTTAATGCTTATCTTTCAAAGTTGTGTTTCTGACATGAAGTGTGATTTTTCTTTTAAGCATGAAGTTAAAGAGTGAA
GGGGTTATGTAAAGTAGAGGGATCTCCTGCTCTTGTTAGGGTATTTTTAAGGTTTTTTCTAGATAGTGTGTCTTTTTGGTATGGTTTCTT
GGTTAGTATTAATACTTTCCCAGACTCCTTGAGAAAAATATTGCACACTCAATGGCTCCAGTGCATGTGACAAGGAAGCATAGGAAAATG
GGGGAAAGAAAGTGTGTGAGGGGACCTAGTTGATTACTTCGGTCTTTTTATGTAGCAGACTGACATTTCATAGCATTGTAGCTAAGAGAT
AAGGAGCACTTTGCTAGTGACAGTGGGCTACGAAAAGTAAATAGAGAGACTTTTTGAAAATGGTAAAAGTTTGAGAAACTTGGGAAGATT
AGTGTGTTAATCAGGCTTGCTAGTTAGTGGATTGCAGAAAGAAAAATGTAGGTGATTAAGCTCTGGGCCTTGTGGTTTATGAGGTCAATT
TTGCTTCACTTTTTTTTTTGTTCTTGCTATAATCACTTTTAGATAAGCTCATTGCTCTTAGCATCATTTTTTAGAGGTTAAAGCAGAAGT
AAATTGCAAACAAATCTGTCAGTTGTGAGCAGATTTCTTTTATGTGTGTGGTTCTCCATCATATTTAACTTTGGATGCTGGAGTGTTGAA
TAGAGATGATGTCAGATATTCCAATAGGCTATCATTTAATGTTAACTGGCAATCACCTAACTGGTTAATCTCAGTTGAGACTGTGCTTCT
GAACTGGGATTGTCTTACTCCCAGGGCTGTGTAAGAAAAGTCATAGGTGGATACAATAATCTCTTTTAAGTATCAGTTTTACTCAGATAT
TTTGGTGGAGATATTTTGTACTAAAACAAGATCTATATCATGGAATAGAATGCTGAATTTGTATGAATTATTCACATAAAGCTTGATCTT
TCAAAAAATAGTTTGCTTGCAGCAAGTGGTATTAGAACACATCCTAAAACAGAATGAAATGATGTCTTTTGCAGCAACTTGGATGGAGCT
GGAGGCCATTATTCTAAGTGAAGTAACTCAGGAATGGAAAGTGAAATACCATATGTTCTCACTTATAAGTGGGAGCTAAGCAATGAGGAT
GCAAAGACATCCAGAGTGATATAATGGACTATGGGGACTTGCAAGGGGAAGCTTGAGAGTGGGGTGAGGGATAAAAGACTACATATTGGG
TACAGTGTACACTGCTCCAGTGATGGGTGCACTAAAATCTCAAAATTCACCACTAAAGAATGTATCCATGTAACCAAAAACCACCTGTAC
CCCCAAAACTATTGAAATCTTAAAATAGTAATAATTAACAAAGTAAAACAAGATCACACCCTGGAACAATTGGAGGATTGCTTGCTGCCC
TGCATCTTAAGGCGTATTCTAGCAGCAAAGCTTGTGATGCACTGACTTGGGGCAAGTAAAACTGATGCTGAGGACAAAGGGAGAAGATGT
TCCTCGCCCAGGGAAATGAAAACTTTTCTTATTCACCTTGCTTGTGCTTAAACACTTATGTTCATCTAGTGTAGAATACATGGCTACTTG
TTTGTAATTTTTTTATTGGTGGAATTAAAGTAATTTTTCCTTATCTTTGAACTTTTATTTAGAGAACTTAAATAAAGCTCTTCTGTCTCC

>24610_24610_3_DYNC1I1-ASB4_DYNC1I1_chr7_95499310_ENST00000437599_ASB4_chr7_95125070_ENST00000325885_length(amino acids)=549AA_BP=185
MPPPRSRRRLGEPSSAAAERVQETNMSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQS
IGISPEPPLVQPLHFLTWDTCYFHYLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLA
THQSEGYWLPSYKLKSSWATGLHLSVLFGHVECLLVLLDHNATINCRPNGKTPLHVACEMANVDCVKILCDRGAKLNCYSLSGHTALHFC
TTPSSILCAKQLVWRGANVNMKTNNQDEETPLHTAAHFGLSELVAFYVEHGAIVDSVNAHMETPLAIAAYWALRFKEQEYSTEHHLVCRM
LLDYKAEVNARDDDFKSPLHKAAWNCDHVLMHMMLEAGAEANLMDINGCAAIQYVLKVTSVRPAAQPEICYQLLLNHGAARIYPPQFHKV
IQACHSCPKAIEVVVNAYEHIRWNTKWRRAIPDDDLEKYWDFYHSLFTVCCNSPRTLMHLSRCAIRRTLHNRCHRAIPLLSLPLSLKKYL

--------------------------------------------------------------
>24610_24610_4_DYNC1I1-ASB4_DYNC1I1_chr7_95499310_ENST00000447467_ASB4_chr7_95125070_ENST00000325885_length(transcript)=4286nt_BP=719nt
AGACTGAGTGCTCCGGGGAGCTGTCAGTGTCAGGCTCTGGGAGAGAGGAAGTGATCGCTCCCGGAGGAGCGCGAGCCGAGCGGCCGGCGC
AGCGTGAGACAGCACATCCTGCCCGCGCCGGCCCCGCCACCTTCGGGAGCCGCCTGCACCAACGCTGCCGCCGCCCAGGAGCCGCCGCCG
GCTCGGGGAGCCCAGTTCCGCCGCTGCCGAGCGCGTCCAGGAAACCAACATGTCTGACAAAAGTGACTTAAAAGCTGAGCTAGAGCGCAA
AAAGCAGCGCTTAGCACAGATAAGAGAAGAGAAGAAACGGAAGGAAGAGGAGAGGAAAAAGAAAGAGGCTGATATGCAGCAGAAGAAAGA
ACCCGTTCAGGACGACTCTGATCTGGATCGCAAACGACGAGAGACAGAGGCTTTGCTGCAAAGCATTGGTATCTCACCGGAGCCGCCTCT
AGTCCCAACCCCTATGTCTCCCTCCTCGAAATCAGTGAGCACTCCCAGTGAAGCTGGAAGCCAAGACTCAGGCGATCTGGGGCCATTAAC
AAGGACCCTGCAGTGGGACACAGACCCCTCAGTGCTCCAGCTGCAGTCAGACTCAGAACTTGGAAGAAGACTGCATAAACTGGGCGTGTC
AAAGGTCACCCAAGTGGATTTCCTGCCAAGGGAAGTAGTGTCCTACTCAAAGGAGACCCAGACTCCTCTTGCCACGCATCAGTCTGAAGG
TTACTGGTTGCCTAGCTATAAATTGAAGTCTTCCTGGGCCACAGGCCTCCATCTCTCTGTCTTGTTTGGCCATGTGGAATGTCTTCTGGT
GCTACTGGACCACAATGCTACAATCAACTGTAGACCCAATGGGAAAACCCCTCTTCACGTGGCTTGTGAAATGGCCAATGTGGATTGTGT
TAAGATCCTCTGTGATCGTGGGGCAAAGCTCAATTGCTACTCCTTAAGTGGACACACAGCTTTGCACTTTTGTACAACTCCAAGTTCCAT
TCTCTGTGCCAAGCAATTGGTTTGGAGAGGGGCGAATGTGAACATGAAGACCAACAACCAAGATGAGGAGACGCCCTTGCACACGGCTGC
CCACTTCGGCCTTTCGGAGCTGGTGGCCTTCTACGTGGAACACGGGGCCATAGTGGACAGCGTGAATGCCCACATGGAGACCCCCCTGGC
CATCGCCGCCTACTGGGCCCTCCGCTTTAAGGAGCAGGAGTACAGCACGGAGCACCACCTGGTCTGCCGCATGCTGCTTGACTACAAAGC
CGAAGTCAATGCCCGAGATGACGACTTTAAATCTCCCCTCCACAAGGCAGCCTGGAACTGTGACCACGTGCTCATGCACATGATGCTGGA
AGCTGGCGCCGAAGCCAATCTCATGGATATCAACGGCTGTGCTGCCATCCAGTACGTGCTGAAGGTCACCTCCGTGCGCCCTGCTGCCCA
GCCTGAGATCTGCTACCAGCTCCTGTTGAACCATGGGGCTGCCCGAATATACCCTCCACAGTTCCATAAGGTGATACAGGCCTGCCATTC
TTGTCCTAAAGCAATTGAAGTTGTAGTCAATGCCTATGAACACATCAGATGGAACACAAAGTGGAGAAGAGCTATCCCCGATGATGACTT
GGAGAAATACTGGGATTTTTACCACTCTCTCTTTACTGTGTGCTGTAACTCTCCAAGGACTCTCATGCACTTATCGAGATGTGCCATTAG
AAGAACATTACACAACAGATGCCATAGAGCAATTCCTTTGCTTTCCCTCCCATTGTCATTGAAAAAGTACTTGCTTTTAGAGCCAGAGGG
AATTATTTATTAAGCCTTATGAGACAGCAGTTCCCAATCCTAGGTATTTAAGTGGACTTGCTGGGTAGACACAGTTTGCCTAAATAAAAT
GGTACTTGGGTTGATTATAACACTTCAGGGATTTCAAAACACTTTACAAACACTGCCATTAATCCTAGAATATCATGGTATGGGGAAATA
AAGAAGAAGTAAAGTTAAGGAATTTTCAAAGACAAGGATGTATTCAGAATGTACTGATAGAACAGTAATAACTAATATGTATAGTGTTCT
TACTAAGTACCTGAAATATTTTTGTAAAACTTCTTATATCTTATCTCATCTGAAATGGGACCCAGGTTTTCTTCCAACCAATATAATTCT
GTGCCTTATCAGTAATATGTTTACATTCTCATTCAAATGGCCATATAGCAGGCTTTGCAATTGGCCTCTTAAACTTGGTGTTTTCCCCCA
TTACCCCTTAGCAGTAATTACTGTCACTAGTTTTGCAAACTCCTACTCCCCAAACCAAGCTACTCAAGTTTATTTCAGTGATGAAGGCAT
ATGAGCATAGTCAAAACAAGGAGATCTTGGAGTCAAATTAGAAATGAGAAAGAAACATCAGTCCAGTTAATAGTCAAGAATGGACATTTG
AACCAGACATCACTGAGCCAGAGACTGGAGATGCAAAGATGAGTCCCATGTGACTCCTGCCTTCCAGGATCTCACCATTTAGCAGAGGAT
CCAGACATACACACAGCTAACTGCAATATAAAGTGATGGGGCAAGAGTACAGGTGCAGACTCACTTTTAATGCTTATCTTTCAAAGTTGT
GTTTCTGACATGAAGTGTGATTTTTCTTTTAAGCATGAAGTTAAAGAGTGAAGGGGTTATGTAAAGTAGAGGGATCTCCTGCTCTTGTTA
GGGTATTTTTAAGGTTTTTTCTAGATAGTGTGTCTTTTTGGTATGGTTTCTTGGTTAGTATTAATACTTTCCCAGACTCCTTGAGAAAAA
TATTGCACACTCAATGGCTCCAGTGCATGTGACAAGGAAGCATAGGAAAATGGGGGAAAGAAAGTGTGTGAGGGGACCTAGTTGATTACT
TCGGTCTTTTTATGTAGCAGACTGACATTTCATAGCATTGTAGCTAAGAGATAAGGAGCACTTTGCTAGTGACAGTGGGCTACGAAAAGT
AAATAGAGAGACTTTTTGAAAATGGTAAAAGTTTGAGAAACTTGGGAAGATTAGTGTGTTAATCAGGCTTGCTAGTTAGTGGATTGCAGA
AAGAAAAATGTAGGTGATTAAGCTCTGGGCCTTGTGGTTTATGAGGTCAATTTTGCTTCACTTTTTTTTTTGTTCTTGCTATAATCACTT
TTAGATAAGCTCATTGCTCTTAGCATCATTTTTTAGAGGTTAAAGCAGAAGTAAATTGCAAACAAATCTGTCAGTTGTGAGCAGATTTCT
TTTATGTGTGTGGTTCTCCATCATATTTAACTTTGGATGCTGGAGTGTTGAATAGAGATGATGTCAGATATTCCAATAGGCTATCATTTA
ATGTTAACTGGCAATCACCTAACTGGTTAATCTCAGTTGAGACTGTGCTTCTGAACTGGGATTGTCTTACTCCCAGGGCTGTGTAAGAAA
AGTCATAGGTGGATACAATAATCTCTTTTAAGTATCAGTTTTACTCAGATATTTTGGTGGAGATATTTTGTACTAAAACAAGATCTATAT
CATGGAATAGAATGCTGAATTTGTATGAATTATTCACATAAAGCTTGATCTTTCAAAAAATAGTTTGCTTGCAGCAAGTGGTATTAGAAC
ACATCCTAAAACAGAATGAAATGATGTCTTTTGCAGCAACTTGGATGGAGCTGGAGGCCATTATTCTAAGTGAAGTAACTCAGGAATGGA
AAGTGAAATACCATATGTTCTCACTTATAAGTGGGAGCTAAGCAATGAGGATGCAAAGACATCCAGAGTGATATAATGGACTATGGGGAC
TTGCAAGGGGAAGCTTGAGAGTGGGGTGAGGGATAAAAGACTACATATTGGGTACAGTGTACACTGCTCCAGTGATGGGTGCACTAAAAT
CTCAAAATTCACCACTAAAGAATGTATCCATGTAACCAAAAACCACCTGTACCCCCAAAACTATTGAAATCTTAAAATAGTAATAATTAA
CAAAGTAAAACAAGATCACACCCTGGAACAATTGGAGGATTGCTTGCTGCCCTGCATCTTAAGGCGTATTCTAGCAGCAAAGCTTGTGAT
GCACTGACTTGGGGCAAGTAAAACTGATGCTGAGGACAAAGGGAGAAGATGTTCCTCGCCCAGGGAAATGAAAACTTTTCTTATTCACCT
TGCTTGTGCTTAAACACTTATGTTCATCTAGTGTAGAATACATGGCTACTTGTTTGTAATTTTTTTATTGGTGGAATTAAAGTAATTTTT

>24610_24610_4_DYNC1I1-ASB4_DYNC1I1_chr7_95499310_ENST00000447467_ASB4_chr7_95125070_ENST00000325885_length(amino acids)=552AA_BP=188
MPPPRSRRRLGEPSSAAAERVQETNMSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQS
IGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQT
PLATHQSEGYWLPSYKLKSSWATGLHLSVLFGHVECLLVLLDHNATINCRPNGKTPLHVACEMANVDCVKILCDRGAKLNCYSLSGHTAL
HFCTTPSSILCAKQLVWRGANVNMKTNNQDEETPLHTAAHFGLSELVAFYVEHGAIVDSVNAHMETPLAIAAYWALRFKEQEYSTEHHLV
CRMLLDYKAEVNARDDDFKSPLHKAAWNCDHVLMHMMLEAGAEANLMDINGCAAIQYVLKVTSVRPAAQPEICYQLLLNHGAARIYPPQF
HKVIQACHSCPKAIEVVVNAYEHIRWNTKWRRAIPDDDLEKYWDFYHSLFTVCCNSPRTLMHLSRCAIRRTLHNRCHRAIPLLSLPLSLK

--------------------------------------------------------------
>24610_24610_5_DYNC1I1-ASB4_DYNC1I1_chr7_95499310_ENST00000457059_ASB4_chr7_95125070_ENST00000325885_length(transcript)=4157nt_BP=590nt
ATATCTCTAGGGGTTTATGACAGGCTGTTTTCTTTTCTCAGTGTGGGGATGAATTGCTCCATTATCATCTAAATTGGAAGTCATGATGAT
GGAAACCAACATGTCTGACAAAAGTGACTTAAAAGCTGAGCTAGAGCGCAAAAAGCAGCGCTTAGCACAGATAAGAGAAGAGAAGAAACG
GAAGGAAGAGGAGAGGAAAAAGAAAGAGGCTGATATGCAGCAGAAGAAAGAACCCGTTCAGGACGACTCTGATCTGGATCGCAAACGACG
AGAGACAGAGGCTTTGCTGCAAAGCATTGGTATCTCACCGGAGCCGCCTCTAGTCCCAACCCCTATGTCTCCCTCCTCGAAATCAGTGAG
CACTCCCAGTGAAGCTGGAAGCCAAGACTCAGGCGATCTGGGGCCATTAACAAGGACCCTGCAGTGGGACACAGACCCCTCAGTGCTCCA
GCTGCAGTCAGACTCAGAACTTGGAAGAAGACTGCATAAACTGGGCGTGTCAAAGGTCACCCAAGTGGATTTCCTGCCAAGGGAAGTAGT
GTCCTACTCAAAGGAGACCCAGACTCCTCTTGCCACGCATCAGTCTGAAGGTTACTGGTTGCCTAGCTATAAATTGAAGTCTTCCTGGGC
CACAGGCCTCCATCTCTCTGTCTTGTTTGGCCATGTGGAATGTCTTCTGGTGCTACTGGACCACAATGCTACAATCAACTGTAGACCCAA
TGGGAAAACCCCTCTTCACGTGGCTTGTGAAATGGCCAATGTGGATTGTGTTAAGATCCTCTGTGATCGTGGGGCAAAGCTCAATTGCTA
CTCCTTAAGTGGACACACAGCTTTGCACTTTTGTACAACTCCAAGTTCCATTCTCTGTGCCAAGCAATTGGTTTGGAGAGGGGCGAATGT
GAACATGAAGACCAACAACCAAGATGAGGAGACGCCCTTGCACACGGCTGCCCACTTCGGCCTTTCGGAGCTGGTGGCCTTCTACGTGGA
ACACGGGGCCATAGTGGACAGCGTGAATGCCCACATGGAGACCCCCCTGGCCATCGCCGCCTACTGGGCCCTCCGCTTTAAGGAGCAGGA
GTACAGCACGGAGCACCACCTGGTCTGCCGCATGCTGCTTGACTACAAAGCCGAAGTCAATGCCCGAGATGACGACTTTAAATCTCCCCT
CCACAAGGCAGCCTGGAACTGTGACCACGTGCTCATGCACATGATGCTGGAAGCTGGCGCCGAAGCCAATCTCATGGATATCAACGGCTG
TGCTGCCATCCAGTACGTGCTGAAGGTCACCTCCGTGCGCCCTGCTGCCCAGCCTGAGATCTGCTACCAGCTCCTGTTGAACCATGGGGC
TGCCCGAATATACCCTCCACAGTTCCATAAGGTGATACAGGCCTGCCATTCTTGTCCTAAAGCAATTGAAGTTGTAGTCAATGCCTATGA
ACACATCAGATGGAACACAAAGTGGAGAAGAGCTATCCCCGATGATGACTTGGAGAAATACTGGGATTTTTACCACTCTCTCTTTACTGT
GTGCTGTAACTCTCCAAGGACTCTCATGCACTTATCGAGATGTGCCATTAGAAGAACATTACACAACAGATGCCATAGAGCAATTCCTTT
GCTTTCCCTCCCATTGTCATTGAAAAAGTACTTGCTTTTAGAGCCAGAGGGAATTATTTATTAAGCCTTATGAGACAGCAGTTCCCAATC
CTAGGTATTTAAGTGGACTTGCTGGGTAGACACAGTTTGCCTAAATAAAATGGTACTTGGGTTGATTATAACACTTCAGGGATTTCAAAA
CACTTTACAAACACTGCCATTAATCCTAGAATATCATGGTATGGGGAAATAAAGAAGAAGTAAAGTTAAGGAATTTTCAAAGACAAGGAT
GTATTCAGAATGTACTGATAGAACAGTAATAACTAATATGTATAGTGTTCTTACTAAGTACCTGAAATATTTTTGTAAAACTTCTTATAT
CTTATCTCATCTGAAATGGGACCCAGGTTTTCTTCCAACCAATATAATTCTGTGCCTTATCAGTAATATGTTTACATTCTCATTCAAATG
GCCATATAGCAGGCTTTGCAATTGGCCTCTTAAACTTGGTGTTTTCCCCCATTACCCCTTAGCAGTAATTACTGTCACTAGTTTTGCAAA
CTCCTACTCCCCAAACCAAGCTACTCAAGTTTATTTCAGTGATGAAGGCATATGAGCATAGTCAAAACAAGGAGATCTTGGAGTCAAATT
AGAAATGAGAAAGAAACATCAGTCCAGTTAATAGTCAAGAATGGACATTTGAACCAGACATCACTGAGCCAGAGACTGGAGATGCAAAGA
TGAGTCCCATGTGACTCCTGCCTTCCAGGATCTCACCATTTAGCAGAGGATCCAGACATACACACAGCTAACTGCAATATAAAGTGATGG
GGCAAGAGTACAGGTGCAGACTCACTTTTAATGCTTATCTTTCAAAGTTGTGTTTCTGACATGAAGTGTGATTTTTCTTTTAAGCATGAA
GTTAAAGAGTGAAGGGGTTATGTAAAGTAGAGGGATCTCCTGCTCTTGTTAGGGTATTTTTAAGGTTTTTTCTAGATAGTGTGTCTTTTT
GGTATGGTTTCTTGGTTAGTATTAATACTTTCCCAGACTCCTTGAGAAAAATATTGCACACTCAATGGCTCCAGTGCATGTGACAAGGAA
GCATAGGAAAATGGGGGAAAGAAAGTGTGTGAGGGGACCTAGTTGATTACTTCGGTCTTTTTATGTAGCAGACTGACATTTCATAGCATT
GTAGCTAAGAGATAAGGAGCACTTTGCTAGTGACAGTGGGCTACGAAAAGTAAATAGAGAGACTTTTTGAAAATGGTAAAAGTTTGAGAA
ACTTGGGAAGATTAGTGTGTTAATCAGGCTTGCTAGTTAGTGGATTGCAGAAAGAAAAATGTAGGTGATTAAGCTCTGGGCCTTGTGGTT
TATGAGGTCAATTTTGCTTCACTTTTTTTTTTGTTCTTGCTATAATCACTTTTAGATAAGCTCATTGCTCTTAGCATCATTTTTTAGAGG
TTAAAGCAGAAGTAAATTGCAAACAAATCTGTCAGTTGTGAGCAGATTTCTTTTATGTGTGTGGTTCTCCATCATATTTAACTTTGGATG
CTGGAGTGTTGAATAGAGATGATGTCAGATATTCCAATAGGCTATCATTTAATGTTAACTGGCAATCACCTAACTGGTTAATCTCAGTTG
AGACTGTGCTTCTGAACTGGGATTGTCTTACTCCCAGGGCTGTGTAAGAAAAGTCATAGGTGGATACAATAATCTCTTTTAAGTATCAGT
TTTACTCAGATATTTTGGTGGAGATATTTTGTACTAAAACAAGATCTATATCATGGAATAGAATGCTGAATTTGTATGAATTATTCACAT
AAAGCTTGATCTTTCAAAAAATAGTTTGCTTGCAGCAAGTGGTATTAGAACACATCCTAAAACAGAATGAAATGATGTCTTTTGCAGCAA
CTTGGATGGAGCTGGAGGCCATTATTCTAAGTGAAGTAACTCAGGAATGGAAAGTGAAATACCATATGTTCTCACTTATAAGTGGGAGCT
AAGCAATGAGGATGCAAAGACATCCAGAGTGATATAATGGACTATGGGGACTTGCAAGGGGAAGCTTGAGAGTGGGGTGAGGGATAAAAG
ACTACATATTGGGTACAGTGTACACTGCTCCAGTGATGGGTGCACTAAAATCTCAAAATTCACCACTAAAGAATGTATCCATGTAACCAA
AAACCACCTGTACCCCCAAAACTATTGAAATCTTAAAATAGTAATAATTAACAAAGTAAAACAAGATCACACCCTGGAACAATTGGAGGA
TTGCTTGCTGCCCTGCATCTTAAGGCGTATTCTAGCAGCAAAGCTTGTGATGCACTGACTTGGGGCAAGTAAAACTGATGCTGAGGACAA
AGGGAGAAGATGTTCCTCGCCCAGGGAAATGAAAACTTTTCTTATTCACCTTGCTTGTGCTTAAACACTTATGTTCATCTAGTGTAGAAT
ACATGGCTACTTGTTTGTAATTTTTTTATTGGTGGAATTAAAGTAATTTTTCCTTATCTTTGAACTTTTATTTAGAGAACTTAAATAAAG

>24610_24610_5_DYNC1I1-ASB4_DYNC1I1_chr7_95499310_ENST00000457059_ASB4_chr7_95125070_ENST00000325885_length(amino acids)=536AA_BP=172
MEVMMMETNMSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQSIGISPEPPLVPTPMSP
SSKSVSTPSEAGSQDSGDLGPLTRTLQWDTDPSVLQLQSDSELGRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEGYWLPSYK
LKSSWATGLHLSVLFGHVECLLVLLDHNATINCRPNGKTPLHVACEMANVDCVKILCDRGAKLNCYSLSGHTALHFCTTPSSILCAKQLV
WRGANVNMKTNNQDEETPLHTAAHFGLSELVAFYVEHGAIVDSVNAHMETPLAIAAYWALRFKEQEYSTEHHLVCRMLLDYKAEVNARDD
DFKSPLHKAAWNCDHVLMHMMLEAGAEANLMDINGCAAIQYVLKVTSVRPAAQPEICYQLLLNHGAARIYPPQFHKVIQACHSCPKAIEV

--------------------------------------------------------------
>24610_24610_6_DYNC1I1-ASB4_DYNC1I1_chr7_95499310_ENST00000537881_ASB4_chr7_95125070_ENST00000325885_length(transcript)=4186nt_BP=619nt
GAGAGAGGAAGTGATCGCTCCCGGAGGAGCGCGAGCCGAGCGGCCGGCGCAGCGTGAGACAGCACATCCTGCCCGCGCCGGCCCCGCCAC
CTTCGGGAGCCGCCTGCACCAACGCTGCCGCCGCCCAGGAGCCGCCGCCGGCTCGGGGAGCCCAGTTCCGCCGCTGCCGAGCGCGTCCAG
GAAACCAACATGTCTGACAAAAGTGACTTAAAAGCTGAGCTAGAGCGCAAAAAGCAGCGCTTAGCACAGATAAGAGAAGAGAAGAAACGG
AAGGAAGAGGAGAGGAAAAAGAAAGAGGCTGATATGCAGCAGAAGAAAGAACCCGTTCAGGACGACTCTGATCTGGATCGCAAACGACGA
GAGACAGAGGCTTTGCTGCAAAGCATTGGTATCTCACCGGAGCCGCCTCTAGTCCCAACCCCTATGTCTCCCTCCTCGAAATCAGTGAGC
ACTCCCAGTGAAGCTGGAAGCCAAGACTCAGGCGATCTGGGGCCATTAACAAGAAGAAGACTGCATAAACTGGGCGTGTCAAAGGTCACC
CAAGTGGATTTCCTGCCAAGGGAAGTAGTGTCCTACTCAAAGGAGACCCAGACTCCTCTTGCCACGCATCAGTCTGAAGGTTACTGGTTG
CCTAGCTATAAATTGAAGTCTTCCTGGGCCACAGGCCTCCATCTCTCTGTCTTGTTTGGCCATGTGGAATGTCTTCTGGTGCTACTGGAC
CACAATGCTACAATCAACTGTAGACCCAATGGGAAAACCCCTCTTCACGTGGCTTGTGAAATGGCCAATGTGGATTGTGTTAAGATCCTC
TGTGATCGTGGGGCAAAGCTCAATTGCTACTCCTTAAGTGGACACACAGCTTTGCACTTTTGTACAACTCCAAGTTCCATTCTCTGTGCC
AAGCAATTGGTTTGGAGAGGGGCGAATGTGAACATGAAGACCAACAACCAAGATGAGGAGACGCCCTTGCACACGGCTGCCCACTTCGGC
CTTTCGGAGCTGGTGGCCTTCTACGTGGAACACGGGGCCATAGTGGACAGCGTGAATGCCCACATGGAGACCCCCCTGGCCATCGCCGCC
TACTGGGCCCTCCGCTTTAAGGAGCAGGAGTACAGCACGGAGCACCACCTGGTCTGCCGCATGCTGCTTGACTACAAAGCCGAAGTCAAT
GCCCGAGATGACGACTTTAAATCTCCCCTCCACAAGGCAGCCTGGAACTGTGACCACGTGCTCATGCACATGATGCTGGAAGCTGGCGCC
GAAGCCAATCTCATGGATATCAACGGCTGTGCTGCCATCCAGTACGTGCTGAAGGTCACCTCCGTGCGCCCTGCTGCCCAGCCTGAGATC
TGCTACCAGCTCCTGTTGAACCATGGGGCTGCCCGAATATACCCTCCACAGTTCCATAAGGTGATACAGGCCTGCCATTCTTGTCCTAAA
GCAATTGAAGTTGTAGTCAATGCCTATGAACACATCAGATGGAACACAAAGTGGAGAAGAGCTATCCCCGATGATGACTTGGAGAAATAC
TGGGATTTTTACCACTCTCTCTTTACTGTGTGCTGTAACTCTCCAAGGACTCTCATGCACTTATCGAGATGTGCCATTAGAAGAACATTA
CACAACAGATGCCATAGAGCAATTCCTTTGCTTTCCCTCCCATTGTCATTGAAAAAGTACTTGCTTTTAGAGCCAGAGGGAATTATTTAT
TAAGCCTTATGAGACAGCAGTTCCCAATCCTAGGTATTTAAGTGGACTTGCTGGGTAGACACAGTTTGCCTAAATAAAATGGTACTTGGG
TTGATTATAACACTTCAGGGATTTCAAAACACTTTACAAACACTGCCATTAATCCTAGAATATCATGGTATGGGGAAATAAAGAAGAAGT
AAAGTTAAGGAATTTTCAAAGACAAGGATGTATTCAGAATGTACTGATAGAACAGTAATAACTAATATGTATAGTGTTCTTACTAAGTAC
CTGAAATATTTTTGTAAAACTTCTTATATCTTATCTCATCTGAAATGGGACCCAGGTTTTCTTCCAACCAATATAATTCTGTGCCTTATC
AGTAATATGTTTACATTCTCATTCAAATGGCCATATAGCAGGCTTTGCAATTGGCCTCTTAAACTTGGTGTTTTCCCCCATTACCCCTTA
GCAGTAATTACTGTCACTAGTTTTGCAAACTCCTACTCCCCAAACCAAGCTACTCAAGTTTATTTCAGTGATGAAGGCATATGAGCATAG
TCAAAACAAGGAGATCTTGGAGTCAAATTAGAAATGAGAAAGAAACATCAGTCCAGTTAATAGTCAAGAATGGACATTTGAACCAGACAT
CACTGAGCCAGAGACTGGAGATGCAAAGATGAGTCCCATGTGACTCCTGCCTTCCAGGATCTCACCATTTAGCAGAGGATCCAGACATAC
ACACAGCTAACTGCAATATAAAGTGATGGGGCAAGAGTACAGGTGCAGACTCACTTTTAATGCTTATCTTTCAAAGTTGTGTTTCTGACA
TGAAGTGTGATTTTTCTTTTAAGCATGAAGTTAAAGAGTGAAGGGGTTATGTAAAGTAGAGGGATCTCCTGCTCTTGTTAGGGTATTTTT
AAGGTTTTTTCTAGATAGTGTGTCTTTTTGGTATGGTTTCTTGGTTAGTATTAATACTTTCCCAGACTCCTTGAGAAAAATATTGCACAC
TCAATGGCTCCAGTGCATGTGACAAGGAAGCATAGGAAAATGGGGGAAAGAAAGTGTGTGAGGGGACCTAGTTGATTACTTCGGTCTTTT
TATGTAGCAGACTGACATTTCATAGCATTGTAGCTAAGAGATAAGGAGCACTTTGCTAGTGACAGTGGGCTACGAAAAGTAAATAGAGAG
ACTTTTTGAAAATGGTAAAAGTTTGAGAAACTTGGGAAGATTAGTGTGTTAATCAGGCTTGCTAGTTAGTGGATTGCAGAAAGAAAAATG
TAGGTGATTAAGCTCTGGGCCTTGTGGTTTATGAGGTCAATTTTGCTTCACTTTTTTTTTTGTTCTTGCTATAATCACTTTTAGATAAGC
TCATTGCTCTTAGCATCATTTTTTAGAGGTTAAAGCAGAAGTAAATTGCAAACAAATCTGTCAGTTGTGAGCAGATTTCTTTTATGTGTG
TGGTTCTCCATCATATTTAACTTTGGATGCTGGAGTGTTGAATAGAGATGATGTCAGATATTCCAATAGGCTATCATTTAATGTTAACTG
GCAATCACCTAACTGGTTAATCTCAGTTGAGACTGTGCTTCTGAACTGGGATTGTCTTACTCCCAGGGCTGTGTAAGAAAAGTCATAGGT
GGATACAATAATCTCTTTTAAGTATCAGTTTTACTCAGATATTTTGGTGGAGATATTTTGTACTAAAACAAGATCTATATCATGGAATAG
AATGCTGAATTTGTATGAATTATTCACATAAAGCTTGATCTTTCAAAAAATAGTTTGCTTGCAGCAAGTGGTATTAGAACACATCCTAAA
ACAGAATGAAATGATGTCTTTTGCAGCAACTTGGATGGAGCTGGAGGCCATTATTCTAAGTGAAGTAACTCAGGAATGGAAAGTGAAATA
CCATATGTTCTCACTTATAAGTGGGAGCTAAGCAATGAGGATGCAAAGACATCCAGAGTGATATAATGGACTATGGGGACTTGCAAGGGG
AAGCTTGAGAGTGGGGTGAGGGATAAAAGACTACATATTGGGTACAGTGTACACTGCTCCAGTGATGGGTGCACTAAAATCTCAAAATTC
ACCACTAAAGAATGTATCCATGTAACCAAAAACCACCTGTACCCCCAAAACTATTGAAATCTTAAAATAGTAATAATTAACAAAGTAAAA
CAAGATCACACCCTGGAACAATTGGAGGATTGCTTGCTGCCCTGCATCTTAAGGCGTATTCTAGCAGCAAAGCTTGTGATGCACTGACTT
GGGGCAAGTAAAACTGATGCTGAGGACAAAGGGAGAAGATGTTCCTCGCCCAGGGAAATGAAAACTTTTCTTATTCACCTTGCTTGTGCT
TAAACACTTATGTTCATCTAGTGTAGAATACATGGCTACTTGTTTGTAATTTTTTTATTGGTGGAATTAAAGTAATTTTTCCTTATCTTT

>24610_24610_6_DYNC1I1-ASB4_DYNC1I1_chr7_95499310_ENST00000537881_ASB4_chr7_95125070_ENST00000325885_length(amino acids)=532AA_BP=168
MPPPRSRRRLGEPSSAAAERVQETNMSDKSDLKAELERKKQRLAQIREEKKRKEEERKKKEADMQQKKEPVQDDSDLDRKRRETEALLQS
IGISPEPPLVPTPMSPSSKSVSTPSEAGSQDSGDLGPLTRRRLHKLGVSKVTQVDFLPREVVSYSKETQTPLATHQSEGYWLPSYKLKSS
WATGLHLSVLFGHVECLLVLLDHNATINCRPNGKTPLHVACEMANVDCVKILCDRGAKLNCYSLSGHTALHFCTTPSSILCAKQLVWRGA
NVNMKTNNQDEETPLHTAAHFGLSELVAFYVEHGAIVDSVNAHMETPLAIAAYWALRFKEQEYSTEHHLVCRMLLDYKAEVNARDDDFKS
PLHKAAWNCDHVLMHMMLEAGAEANLMDINGCAAIQYVLKVTSVRPAAQPEICYQLLLNHGAARIYPPQFHKVIQACHSCPKAIEVVVNA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for DYNC1I1-ASB4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000324972+6172_123180.33333333333334646.0DCTN1
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000359388+5162_123143.33333333333334609.0DCTN1
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000447467+6172_123163.33333333333334629.0DCTN1
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000457059+6172_123163.33333333333334629.0DCTN1
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000324972+617147_163180.33333333333334646.0DYNLT1
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000447467+617147_163163.33333333333334629.0DYNLT1
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000457059+617147_163163.33333333333334629.0DYNLT1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneDYNC1I1chr7:95499310chr7:95125070ENST00000359388+516147_163143.33333333333334609.0DYNLT1


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for DYNC1I1-ASB4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for DYNC1I1-ASB4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource