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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:EBF2-YAP1 (FusionGDB2 ID:24824)

Fusion Gene Summary for EBF2-YAP1

check button Fusion gene summary
Fusion gene informationFusion gene name: EBF2-YAP1
Fusion gene ID: 24824
HgeneTgene
Gene symbol

EBF2

YAP1

Gene ID

64641

10413

Gene nameEBF transcription factor 2Yes1 associated transcriptional regulator
SynonymsCOE2|EBF-2|O/E-3|OE-3COB1|YAP|YAP2|YAP65|YKI
Cytomap

8p21.2

11q22.1

Type of geneprotein-codingprotein-coding
Descriptiontranscription factor COE2Collier, Olf and EBF 2Collier, Olf and EBF transcription factor 2OLF-1/EBF-LIKE 3early B cell factor 2metencephalon-mesencephalnon-olfactory transcription factor 1transcriptional coactivator YAP165 kDa Yes-associated proteinYes associated protein 1protein yorkie homologyes-associated protein 1yes-associated protein 2yes-associated protein YAP65 homologyorkie homolog
Modification date2020031320200329
UniProtAcc

Q9HAK2

.
Ensembl transtripts involved in fusion geneENST00000408929, ENST00000520164, 
ENST00000535548, 		ENST00000528834, 
ENST00000282441, ENST00000345877, 
ENST00000524575, ENST00000526343, 
ENST00000531439, ENST00000537274, 
Fusion gene scores* DoF score1 X 1 X 1=120 X 10 X 13=2600
# samples 121
** MAII scorelog2(1/1*10)=3.32192809488736log2(21/2600*10)=-3.63005039024969
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EBF2 [Title/Abstract] AND YAP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEBF2(25890600)-YAP1(102033186), # samples:1
Anticipated loss of major functional domain due to fusion event.EBF2-YAP1 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
EBF2-YAP1 seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
EBF2-YAP1 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneYAP1

GO:0006974

cellular response to DNA damage stimulus

18280240

TgeneYAP1

GO:0008283

cell proliferation

17974916

TgeneYAP1

GO:0032570

response to progesterone

16772533

TgeneYAP1

GO:0033148

positive regulation of intracellular estrogen receptor signaling pathway

16772533

TgeneYAP1

GO:0045893

positive regulation of transcription, DNA-templated

20368466

TgeneYAP1

GO:0045944

positive regulation of transcription by RNA polymerase II

25796446

TgeneYAP1

GO:0050767

regulation of neurogenesis

25433207

TgeneYAP1

GO:0050847

progesterone receptor signaling pathway

16772533

TgeneYAP1

GO:0060242

contact inhibition

17974916

TgeneYAP1

GO:0065003

protein-containing complex assembly

20368466

TgeneYAP1

GO:0071480

cellular response to gamma radiation

18280240

TgeneYAP1

GO:0072091

regulation of stem cell proliferation

25433207


check buttonFusion gene breakpoints across EBF2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across YAP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-CancerTCGA-BH-A0BC-11AEBF2chr8

25890600

-YAP1chr11

102033186

+


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Fusion Gene ORF analysis for EBF2-YAP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000408929ENST00000528834EBF2chr8

25890600

-YAP1chr11

102033186

+
5CDS-intronENST00000520164ENST00000528834EBF2chr8

25890600

-YAP1chr11

102033186

+
Frame-shiftENST00000408929ENST00000282441EBF2chr8

25890600

-YAP1chr11

102033186

+
Frame-shiftENST00000408929ENST00000345877EBF2chr8

25890600

-YAP1chr11

102033186

+
Frame-shiftENST00000408929ENST00000524575EBF2chr8

25890600

-YAP1chr11

102033186

+
Frame-shiftENST00000408929ENST00000526343EBF2chr8

25890600

-YAP1chr11

102033186

+
Frame-shiftENST00000408929ENST00000531439EBF2chr8

25890600

-YAP1chr11

102033186

+
Frame-shiftENST00000408929ENST00000537274EBF2chr8

25890600

-YAP1chr11

102033186

+
In-frameENST00000520164ENST00000282441EBF2chr8

25890600

-YAP1chr11

102033186

+
In-frameENST00000520164ENST00000345877EBF2chr8

25890600

-YAP1chr11

102033186

+
In-frameENST00000520164ENST00000524575EBF2chr8

25890600

-YAP1chr11

102033186

+
In-frameENST00000520164ENST00000526343EBF2chr8

25890600

-YAP1chr11

102033186

+
In-frameENST00000520164ENST00000531439EBF2chr8

25890600

-YAP1chr11

102033186

+
In-frameENST00000520164ENST00000537274EBF2chr8

25890600

-YAP1chr11

102033186

+
intron-3CDSENST00000535548ENST00000282441EBF2chr8

25890600

-YAP1chr11

102033186

+
intron-3CDSENST00000535548ENST00000345877EBF2chr8

25890600

-YAP1chr11

102033186

+
intron-3CDSENST00000535548ENST00000524575EBF2chr8

25890600

-YAP1chr11

102033186

+
intron-3CDSENST00000535548ENST00000526343EBF2chr8

25890600

-YAP1chr11

102033186

+
intron-3CDSENST00000535548ENST00000531439EBF2chr8

25890600

-YAP1chr11

102033186

+
intron-3CDSENST00000535548ENST00000537274EBF2chr8

25890600

-YAP1chr11

102033186

+
intron-intronENST00000535548ENST00000528834EBF2chr8

25890600

-YAP1chr11

102033186

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000520164EBF2chr825890600-ENST00000526343YAP1chr11102033186+252210895381869443
ENST00000520164EBF2chr825890600-ENST00000282441YAP1chr11102033186+551510895382031497
ENST00000520164EBF2chr825890600-ENST00000537274YAP1chr11102033186+547910895381995485
ENST00000520164EBF2chr825890600-ENST00000345877YAP1chr11102033186+536510895381881447
ENST00000520164EBF2chr825890600-ENST00000531439YAP1chr11102033186+200710895381983481
ENST00000520164EBF2chr825890600-ENST00000524575YAP1chr11102033186+224410895382031497

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000520164ENST00000526343EBF2chr825890600-YAP1chr11102033186+0.0040499280.9959501
ENST00000520164ENST00000282441EBF2chr825890600-YAP1chr11102033186+0.0002904040.99970955
ENST00000520164ENST00000537274EBF2chr825890600-YAP1chr11102033186+0.0002648120.9997352
ENST00000520164ENST00000345877EBF2chr825890600-YAP1chr11102033186+0.0003651760.99963486
ENST00000520164ENST00000531439EBF2chr825890600-YAP1chr11102033186+0.0110092770.98899066
ENST00000520164ENST00000524575EBF2chr825890600-YAP1chr11102033186+0.0104112570.98958874

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Fusion Genomic Features for EBF2-YAP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
EBF2chr825890600-YAP1chr11102033186+9.03E-070.99999905
EBF2chr825890600-YAP1chr11102033186+9.03E-070.99999905

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for EBF2-YAP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:25890600/chr11:102033186)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
EBF2

Q9HAK2

.
FUNCTION: Transcription factor that, in osteoblasts, activates the decoy receptor for RANKL, TNFRSF11B, which in turn regulates osteoclast differentiation. Acts in synergy with the Wnt-responsive LEF1/CTNNB1 pathway. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3' (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEBF2chr8:25890600chr11:102033186ENST00000520164-616150_169183576.0Zinc fingerC5-type
TgeneYAP1chr8:25890600chr11:102033186ENST0000028244119298_359190505.0Coiled coilOntology_term=ECO:0000255
TgeneYAP1chr8:25890600chr11:102033186ENST0000034587717298_359190455.0Coiled coilOntology_term=ECO:0000255
TgeneYAP1chr8:25890600chr11:102033186ENST0000052457519298_35912327.0Coiled coilOntology_term=ECO:0000255
TgeneYAP1chr8:25890600chr11:102033186ENST000005245751986_10012327.0Coiled coilOntology_term=ECO:0000269
TgeneYAP1chr8:25890600chr11:102033186ENST0000052634317298_359190451.0Coiled coilOntology_term=ECO:0000255
TgeneYAP1chr8:25890600chr11:102033186ENST0000053143918298_359190489.0Coiled coilOntology_term=ECO:0000255
TgeneYAP1chr8:25890600chr11:102033186ENST0000053727418298_359190493.0Coiled coilOntology_term=ECO:0000255
TgeneYAP1chr8:25890600chr11:102033186ENST0000028244119230_263190505.0DomainWW 2
TgeneYAP1chr8:25890600chr11:102033186ENST0000034587717230_263190455.0DomainWW 2
TgeneYAP1chr8:25890600chr11:102033186ENST0000052457519171_20412327.0DomainWW 1
TgeneYAP1chr8:25890600chr11:102033186ENST0000052457519230_26312327.0DomainWW 2
TgeneYAP1chr8:25890600chr11:102033186ENST0000052634317230_263190451.0DomainWW 2
TgeneYAP1chr8:25890600chr11:102033186ENST0000053143918230_263190489.0DomainWW 2
TgeneYAP1chr8:25890600chr11:102033186ENST0000053727418230_263190493.0DomainWW 2
TgeneYAP1chr8:25890600chr11:102033186ENST0000028244119291_504190505.0RegionNote=Transactivation domain
TgeneYAP1chr8:25890600chr11:102033186ENST0000034587717291_504190455.0RegionNote=Transactivation domain
TgeneYAP1chr8:25890600chr11:102033186ENST0000052457519291_50412327.0RegionNote=Transactivation domain
TgeneYAP1chr8:25890600chr11:102033186ENST0000052634317291_504190451.0RegionNote=Transactivation domain
TgeneYAP1chr8:25890600chr11:102033186ENST0000053143918291_504190489.0RegionNote=Transactivation domain
TgeneYAP1chr8:25890600chr11:102033186ENST0000053727418291_504190493.0RegionNote=Transactivation domain

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEBF2chr8:25890600chr11:102033186ENST00000520164-616453_534183576.0Compositional biasNote=Pro/Ser/Thr-rich
HgeneEBF2chr8:25890600chr11:102033186ENST00000520164-616253_336183576.0DomainNote=IPT/TIG
TgeneYAP1chr8:25890600chr11:102033186ENST000002824411986_100190505.0Coiled coilOntology_term=ECO:0000269
TgeneYAP1chr8:25890600chr11:102033186ENST000003458771786_100190455.0Coiled coilOntology_term=ECO:0000269
TgeneYAP1chr8:25890600chr11:102033186ENST000005263431786_100190451.0Coiled coilOntology_term=ECO:0000269
TgeneYAP1chr8:25890600chr11:102033186ENST000005314391886_100190489.0Coiled coilOntology_term=ECO:0000269
TgeneYAP1chr8:25890600chr11:102033186ENST000005372741886_100190493.0Coiled coilOntology_term=ECO:0000269
TgeneYAP1chr8:25890600chr11:102033186ENST00000282441193_49190505.0Compositional biasNote=Pro-rich
TgeneYAP1chr8:25890600chr11:102033186ENST00000345877173_49190455.0Compositional biasNote=Pro-rich
TgeneYAP1chr8:25890600chr11:102033186ENST00000524575193_4912327.0Compositional biasNote=Pro-rich
TgeneYAP1chr8:25890600chr11:102033186ENST00000526343173_49190451.0Compositional biasNote=Pro-rich
TgeneYAP1chr8:25890600chr11:102033186ENST00000531439183_49190489.0Compositional biasNote=Pro-rich
TgeneYAP1chr8:25890600chr11:102033186ENST00000537274183_49190493.0Compositional biasNote=Pro-rich
TgeneYAP1chr8:25890600chr11:102033186ENST0000028244119171_204190505.0DomainWW 1
TgeneYAP1chr8:25890600chr11:102033186ENST0000034587717171_204190455.0DomainWW 1
TgeneYAP1chr8:25890600chr11:102033186ENST0000052634317171_204190451.0DomainWW 1
TgeneYAP1chr8:25890600chr11:102033186ENST0000053143918171_204190489.0DomainWW 1
TgeneYAP1chr8:25890600chr11:102033186ENST0000053727418171_204190493.0DomainWW 1


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Fusion Gene Sequence for EBF2-YAP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>24824_24824_1_EBF2-YAP1_EBF2_chr8_25890600_ENST00000520164_YAP1_chr11_102033186_ENST00000282441_length(transcript)=5515nt_BP=1089nt
ATTCATGGGGCCCGCGCGCGGCTGCAGCCGGGCTCCGTGGCGCTCGCAGCCACCGCCTCCTCTCGGCTCCAGGTCTTCCCCTTCTTTTTA
CAACTGATCCTGTTGGGGATTTTTTTTTTTTCTAAATTGGAACGGTGGGGAGGAGCAGGGAGGGGGGACCTGGAGGAAGGGGAGAGATTA
GGCAGCCATCAATTTCCTCCAGTTTCTCCCAGAACAGGTGATGCTTCTAAATTGTGATCACTTTCAGGAGGCAGCACTGCAGCTGGAAGG
ATGCGAGCGACCTAGGGTGGAGTGGCTGAGGCGGCAGATCTGAACTTGCGGAGGATAAGAACCCAAACTTTGACTACATCAGTCCGCACC
TCGCCAGTGAAGCAAAGGACGGGTTATCTTTTTTTTTTTTCTAAGACTCAAACTTGGGCACTTGATCCCTTTTCTTGGATTGCTTTGGAG
GAGACGATTTGCTGGCAACGTTGGGAACAGTCAGGACTGTGTTGTAACTCTTACTTTTAAAGCGACAGTAGAGGATCAGACTTTTTAAAT
GTTTGGAATTCAAGATACTTTAGGAAGAGGACCAACTCTGAAAGAGAAATCGCTGGGCGCGGAGATGGATTCGGTCAGGTCCTGGGTCCG
GAATGTCGGAGTGGTGGACGCTAATGTCGCCGCGCAGAGCGGGGTCGCCCTGTCCCGGGCCCACTTTGAGAAACAGCCTCCTTCCAACTT
GAGGAAATCCAACTTCTTTCACTTCGTCCTGGCGCTCTATGACAGGCAGGGCCAGCCGGTGGAGATCGAGCGGACGGCCTTCGTGGACTT
TGTGGAGAATGACAAAGAACAAGGCAACGAGAAGACCAACAACGGCACTCACTACAAGTTACAGCTCCTCTACAGCAACGGTGTCCGCAC
GGAACAGGACCTCTATGTCAGGCTCATCGACTCGGTCACCAAGCAGCCCATCGCTTACGAGGGACAGAATAAGAATCCGGAAATGTGCCG
AGTTCTCCTGACGCACGAAGTGATGTGTAGTCGATGCTGCGAAAAGAAAAGCTGTGGAAACCGAAATGAGACTCCATCGGACCCAGTCAT
AATTGACAGTCACATCGATCAGACAACAACATGGCAGGACCCCAGGAAGGCCATGCTGTCCCAGATGAACGTCACAGCCCCCACCAGTCC
ACCAGTGCAGCAGAATATGATGAACTCGGCTTCAGGTCCTCTTCCTGATGGATGGGAACAAGCCATGACTCAGGATGGAGAAATTTACTA
TATAAACCATAAGAACAAGACCACCTCTTGGCTAGACCCAAGGCTTGACCCTCGTTTTGCCATGAACCAGAGAATCAGTCAGAGTGCTCC
AGTGAAACAGCCACCACCCCTGGCTCCCCAGAGCCCACAGGGAGGCGTCATGGGTGGCAGCAACTCCAACCAGCAGCAACAGATGCGACT
GCAGCAACTGCAGATGGAGAAGGAGAGGCTGCGGCTGAAACAGCAAGAACTGCTTCGGCAGGCAATGCGGAATATCAATCCCAGCACAGC
AAATTCTCCAAAATGTCAGGAGTTAGCCCTGCGTAGCCAGTTACCAACACTGGAGCAGGATGGTGGGACTCAAAATCCAGTGTCTTCTCC
CGGGATGTCTCAGGAATTGAGAACAATGACGACCAATAGCTCAGATCCTTTCCTTAACAGTGGCACCTATCACTCTCGAGATGAGAGTAC
AGACAGTGGACTAAGCATGAGCAGCTACAGTGTCCCTCGAACCCCAGATGACTTCCTGAACAGTGTGGATGAGATGGATACAGGTGATAC
TATCAACCAAAGCACCCTGCCCTCACAGCAGAACCGTTTCCCAGACTACCTTGAAGCCATTCCTGGGACAAATGTGGACCTTGGAACACT
GGAAGGAGATGGAATGAACATAGAAGGAGAGGAGCTGATGCCAAGTCTGCAGGAAGCTTTGAGTTCTGACATCCTTAATGACATGGAGTC
TGTTTTGGCTGCCACCAAGCTAGATAAAGAAAGCTTTCTTACATGGTTATAGAGCCCTCAGGCAGACTGAATTCTAAATCTGTGAAGGAT
CTAAGGAGACACATGCACCGGAAATTTCCATAAGCCAGTTGCAGTTTTCAGGCTAATACAGAAAAAGATGAACAAACGTCCAGCAAGATA
CTTTAATCCTCTATTTTGCTCTTCCTTGTCCATTGCTGCTGTTAATGTATTGCTGACCTCTTTCACAGTTGGCTCTAAAGAATCAAAAGA
AAAAAACTTTTTATTTCTTTTGCTATTAAAACTACTGTTCATTTTGGGGGCTGGGGGAAGTGAGCCTGTTTGGATGATGGATGCCATTCC
TTTTGCCCAGTTAAATGTTCACCAATCATTTTAACTAAATACTCAGACTTAGAAGTCAGATGCTTCATGTCACAGCATTTAGTTTGTTCA
ACAGTTGTTTCTTCAGCTTCCTTTGTCCAGTGGAAAAACATGATTTACTGGTCTGACAAGCCAAAAATGTTATATCTGATATTAAATACT
TAATGCTGATTTGAAGAGATAGCTGAAACCAAGGCTGAAGACTGTTTTACTTTCAGTATTTTCTTTTCCTCCTAGTGCTATCATTAGTCA
CATAATGACCTTGATTTTATTTTAGGAGCTTATAAGGCATGAGACAATTTCCATATAAATATATTAATTATTGCCACATACTCTAATATA
GATTTTGGTGGATAATTTTGTGGGTGTGCATTTTGTTCTGTTTTGTTGGGTTTTTTGTTTTTTTTGTTTTTGGCAGGGTCGGTGGGGGGG
TTGGTTGGTTGGTTGGTTTTGTCGGAACCTAGGCAAATGACCATATTAGTGAATCTGTTAATAGTTGTAGCTTGGGATGGTTATTGTAGT
TGTTTTGGTAAAATCTTCATTTCCTGGTTTTTTTTACCACCTTATTTAAATCTCGATTATCTGCTCTCTCTTTTATATACATACACACAC
CCAAACATAACATTTATAATAGTGTGGTAGTGGAATGTATCCTTTTTTAGGTTTCCCTGCTTTCCAGTTAATTTTTAAAATGGTAGCGCT
TTGTATGCATTTAGAATACATGACTAGTAGTTTATATTTCACTGGTAGTTTAAATCTGGTTGGGGCAGTCTGCAGATGTTTGAAGTAGTT
TAGTGTTCTAGAAAGAGCTATTACTGTGGATAGTGCCTAGGGGAGTGCTCCACGCCCTCTGGGCATACGGTAGATATTATCTGATGAATT
GGAAAGGAGCAAACCAGAAATGGCTTTATTTTCTCCCTTGGACTAATTTTTAAGTCTCGATTGGAATTCAGTGAGTAGGTTCATAATGTG
CATGACAGAAATAAGCTTTATAGTGGTTTACCTTCATTTAGCTTTGGAAGTTTTCTTTGCCTTAGTTTTGGAAGTAAATTCTAGTTTGTA
GTTCTCATTTGTAATGAACACATTAACGACTAGATTAAAATATTGCCTTCAAGATTGTTCTTACTTACAAGACTTGCTCCTACTTCTATG
CTGAAAATTGACCCTGGATAGAATACTATAAGGTTTTGAGTTAGCTGGAAAAGTGATCAGATTAATAAATGTATATTGGTAGTTGAATTT
AGCAAAGAAATAGAGATAATCATGATTATACCTTTATTTTTACAGGAAGAGATGATGTAACTAGAGTATGTGTCTACAGGAGTAATAATG
GTTTCCAAAGAGTATTTTTTAAAGGAACAAAACGAGCATGAATTAACTCTTCAATATAAGCTATGAAGTAATAGTTGGTTGTGAATTAAA
GTGGCACCAGCTAGCACCTCTGTGTTTTAAGGGTCTTTCAATGTTTCTAGAATAAGCCCTTATTTTCAAGGGTTCATAACAGGCATAAAA
TCTCTTCTCCTGGCAAAAGCTGCTATGAAAAGCCTCAGCTTGGGAAGATAGATTTTTTTCCCCCCAATTACAAAATCTAAGTATTTTGGC
CCTTCAATTTGGAGGAGGGCAAAAGTTGGAAGTAAGAAGTTTTATTTTAAGTACTTTCAGTGCTCAAAAAAATGCAATCACTGTGTTGTA
TATAATAGTTCATAGGTTGATCACTCATAATAATTGACTCTAAGGCTTTTATTAAGAAAACAGCAGAAAGATTAAATCTTGAATTAAGTC
TGGGGGGAAATGGCCACTGCAGATGGAGTTTTAGAGTAGTAATGAAATTCTACCTAGAATGCAAAATTGGGTATATGAATTACATAGCAT
GTTGTTGGGATTTTTTTTAATGTGCAGAAGATCAAAGCTACTTGGAAGGAGTGCCTATAATTTGCCAGTAGCCACAGATTAAGATTATAT
CTTATATATCAGCAGATTAGCTTTAGCTTAGGGGGAGGGTGGGAAAGTTTGGGGGGGGGGTTGTGAAGATTTAGGGGGACCTTGATAGAG
AACTTTATAAACTTCTTTCTCTTTAATAAAGACTTGTCTTACACCGTGCTGCCATTAAAGGCAGCTGTTCTAGAGTTTCAGTCACCTAAG
TACACCCACAAAACAATATGAATATGGAGATCTTCCTTTACCCCTCAACTTTAATTTGCCCAGTTATACCTCAGTGTTGTAGCAGTACTG
TGATACCTGGCACAGTGCTTTGATCTTACGATGCCCTCTGTACTGACCTGAAGGAGACCTAAGAGTCCTTTCCCTTTTTGAGTTTGAATC
ATAGCCTTGATGTGGTCTCTTGTTTTATGTCCTTGTTCCTAATGTAAAAGTGCTTAACTGCTTCTTGGTTGTATTGGGTAGCATTGGGAT
AAGATTTTAACTGGGTATTCTTGAATTGCTTTTACAATAAACCAATTTTATAATCTTTAAATTTATCAACTTTTTACATTTGTGTTATTT
TCAGTCAGGGCTTCTTAGATCTACTTATGGTTGATGGAGCACATTGATTTGGAGTTTCAGATCTTCCAAAGCACTATTTGTTGTAATAAC
TTTTCTAAATGTAGTGCCTTTAAAGGAAAAATGAACACAGGGAAGTGACTTTGCTACAAATAATGTTGCTGTGTTAAGTATTCATATTAA
ATACATGCCTTCTATATGGAACATGGCAGAAAGACTGAAAAATAACAGTAATTAATTGTGTAATTCAGAATTCATACCAATCAGTGTTGA
AACTCAAACATTGCAAAAGTGGGTGGCAATATTCAGTGCTTAACACTTTTCTAGCGTTGGTACATCTGAGAAATGAGTGCTCAGGTGGAT
TTTATCCTCGCAAGCATGTTGTTATAAGAATTGTGGGTGTGCCTATCATAACAATTGTTTTCTGTATCTTGAAAAAGTATTCTCCACATT
TTAAATGTTTTATATTAGAGAATTCTTTAATGCACACTTGTCAAATATATATATATAGTACCAATGTTACCTTTTTATTTTTTGTTTTAG
ATGTAAGAGCATGCTCATATGTTAGGTACTTACATAAATTGTTACATTATTTTTTCTTATGTAATACCTTTTTGTTTGTTTATGTGGTTC

>24824_24824_1_EBF2-YAP1_EBF2_chr8_25890600_ENST00000520164_YAP1_chr11_102033186_ENST00000282441_length(amino acids)=497AA_BP=183
MFGIQDTLGRGPTLKEKSLGAEMDSVRSWVRNVGVVDANVAAQSGVALSRAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVD
FVENDKEQGNEKTNNGTHYKLQLLYSNGVRTEQDLYVRLIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPV
IIDSHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASGPLPDGWEQAMTQDGEIYYINHKNKTTSWLDPRLDPRFAMNQRISQSA
PVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKERLRLKQQELLRQAMRNINPSTANSPKCQELALRSQLPTLEQDGGTQNPVSS
PGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGT

--------------------------------------------------------------
>24824_24824_2_EBF2-YAP1_EBF2_chr8_25890600_ENST00000520164_YAP1_chr11_102033186_ENST00000345877_length(transcript)=5365nt_BP=1089nt
ATTCATGGGGCCCGCGCGCGGCTGCAGCCGGGCTCCGTGGCGCTCGCAGCCACCGCCTCCTCTCGGCTCCAGGTCTTCCCCTTCTTTTTA
CAACTGATCCTGTTGGGGATTTTTTTTTTTTCTAAATTGGAACGGTGGGGAGGAGCAGGGAGGGGGGACCTGGAGGAAGGGGAGAGATTA
GGCAGCCATCAATTTCCTCCAGTTTCTCCCAGAACAGGTGATGCTTCTAAATTGTGATCACTTTCAGGAGGCAGCACTGCAGCTGGAAGG
ATGCGAGCGACCTAGGGTGGAGTGGCTGAGGCGGCAGATCTGAACTTGCGGAGGATAAGAACCCAAACTTTGACTACATCAGTCCGCACC
TCGCCAGTGAAGCAAAGGACGGGTTATCTTTTTTTTTTTTCTAAGACTCAAACTTGGGCACTTGATCCCTTTTCTTGGATTGCTTTGGAG
GAGACGATTTGCTGGCAACGTTGGGAACAGTCAGGACTGTGTTGTAACTCTTACTTTTAAAGCGACAGTAGAGGATCAGACTTTTTAAAT
GTTTGGAATTCAAGATACTTTAGGAAGAGGACCAACTCTGAAAGAGAAATCGCTGGGCGCGGAGATGGATTCGGTCAGGTCCTGGGTCCG
GAATGTCGGAGTGGTGGACGCTAATGTCGCCGCGCAGAGCGGGGTCGCCCTGTCCCGGGCCCACTTTGAGAAACAGCCTCCTTCCAACTT
GAGGAAATCCAACTTCTTTCACTTCGTCCTGGCGCTCTATGACAGGCAGGGCCAGCCGGTGGAGATCGAGCGGACGGCCTTCGTGGACTT
TGTGGAGAATGACAAAGAACAAGGCAACGAGAAGACCAACAACGGCACTCACTACAAGTTACAGCTCCTCTACAGCAACGGTGTCCGCAC
GGAACAGGACCTCTATGTCAGGCTCATCGACTCGGTCACCAAGCAGCCCATCGCTTACGAGGGACAGAATAAGAATCCGGAAATGTGCCG
AGTTCTCCTGACGCACGAAGTGATGTGTAGTCGATGCTGCGAAAAGAAAAGCTGTGGAAACCGAAATGAGACTCCATCGGACCCAGTCAT
AATTGACAGTCACATCGATCAGACAACAACATGGCAGGACCCCAGGAAGGCCATGCTGTCCCAGATGAACGTCACAGCCCCCACCAGTCC
ACCAGTGCAGCAGAATATGATGAACTCGGCTTCAGCCATGAACCAGAGAATCAGTCAGAGTGCTCCAGTGAAACAGCCACCACCCCTGGC
TCCCCAGAGCCCACAGGGAGGCGTCATGGGTGGCAGCAACTCCAACCAGCAGCAACAGATGCGACTGCAGCAACTGCAGATGGAGAAGGA
GAGGCTGCGGCTGAAACAGCAAGAACTGCTTCGGCAGGTGAGGCCACAGGAGTTAGCCCTGCGTAGCCAGTTACCAACACTGGAGCAGGA
TGGTGGGACTCAAAATCCAGTGTCTTCTCCCGGGATGTCTCAGGAATTGAGAACAATGACGACCAATAGCTCAGATCCTTTCCTTAACAG
TGGCACCTATCACTCTCGAGATGAGAGTACAGACAGTGGACTAAGCATGAGCAGCTACAGTGTCCCTCGAACCCCAGATGACTTCCTGAA
CAGTGTGGATGAGATGGATACAGGTGATACTATCAACCAAAGCACCCTGCCCTCACAGCAGAACCGTTTCCCAGACTACCTTGAAGCCAT
TCCTGGGACAAATGTGGACCTTGGAACACTGGAAGGAGATGGAATGAACATAGAAGGAGAGGAGCTGATGCCAAGTCTGCAGGAAGCTTT
GAGTTCTGACATCCTTAATGACATGGAGTCTGTTTTGGCTGCCACCAAGCTAGATAAAGAAAGCTTTCTTACATGGTTATAGAGCCCTCA
GGCAGACTGAATTCTAAATCTGTGAAGGATCTAAGGAGACACATGCACCGGAAATTTCCATAAGCCAGTTGCAGTTTTCAGGCTAATACA
GAAAAAGATGAACAAACGTCCAGCAAGATACTTTAATCCTCTATTTTGCTCTTCCTTGTCCATTGCTGCTGTTAATGTATTGCTGACCTC
TTTCACAGTTGGCTCTAAAGAATCAAAAGAAAAAAACTTTTTATTTCTTTTGCTATTAAAACTACTGTTCATTTTGGGGGCTGGGGGAAG
TGAGCCTGTTTGGATGATGGATGCCATTCCTTTTGCCCAGTTAAATGTTCACCAATCATTTTAACTAAATACTCAGACTTAGAAGTCAGA
TGCTTCATGTCACAGCATTTAGTTTGTTCAACAGTTGTTTCTTCAGCTTCCTTTGTCCAGTGGAAAAACATGATTTACTGGTCTGACAAG
CCAAAAATGTTATATCTGATATTAAATACTTAATGCTGATTTGAAGAGATAGCTGAAACCAAGGCTGAAGACTGTTTTACTTTCAGTATT
TTCTTTTCCTCCTAGTGCTATCATTAGTCACATAATGACCTTGATTTTATTTTAGGAGCTTATAAGGCATGAGACAATTTCCATATAAAT
ATATTAATTATTGCCACATACTCTAATATAGATTTTGGTGGATAATTTTGTGGGTGTGCATTTTGTTCTGTTTTGTTGGGTTTTTTGTTT
TTTTTGTTTTTGGCAGGGTCGGTGGGGGGGTTGGTTGGTTGGTTGGTTTTGTCGGAACCTAGGCAAATGACCATATTAGTGAATCTGTTA
ATAGTTGTAGCTTGGGATGGTTATTGTAGTTGTTTTGGTAAAATCTTCATTTCCTGGTTTTTTTTACCACCTTATTTAAATCTCGATTAT
CTGCTCTCTCTTTTATATACATACACACACCCAAACATAACATTTATAATAGTGTGGTAGTGGAATGTATCCTTTTTTAGGTTTCCCTGC
TTTCCAGTTAATTTTTAAAATGGTAGCGCTTTGTATGCATTTAGAATACATGACTAGTAGTTTATATTTCACTGGTAGTTTAAATCTGGT
TGGGGCAGTCTGCAGATGTTTGAAGTAGTTTAGTGTTCTAGAAAGAGCTATTACTGTGGATAGTGCCTAGGGGAGTGCTCCACGCCCTCT
GGGCATACGGTAGATATTATCTGATGAATTGGAAAGGAGCAAACCAGAAATGGCTTTATTTTCTCCCTTGGACTAATTTTTAAGTCTCGA
TTGGAATTCAGTGAGTAGGTTCATAATGTGCATGACAGAAATAAGCTTTATAGTGGTTTACCTTCATTTAGCTTTGGAAGTTTTCTTTGC
CTTAGTTTTGGAAGTAAATTCTAGTTTGTAGTTCTCATTTGTAATGAACACATTAACGACTAGATTAAAATATTGCCTTCAAGATTGTTC
TTACTTACAAGACTTGCTCCTACTTCTATGCTGAAAATTGACCCTGGATAGAATACTATAAGGTTTTGAGTTAGCTGGAAAAGTGATCAG
ATTAATAAATGTATATTGGTAGTTGAATTTAGCAAAGAAATAGAGATAATCATGATTATACCTTTATTTTTACAGGAAGAGATGATGTAA
CTAGAGTATGTGTCTACAGGAGTAATAATGGTTTCCAAAGAGTATTTTTTAAAGGAACAAAACGAGCATGAATTAACTCTTCAATATAAG
CTATGAAGTAATAGTTGGTTGTGAATTAAAGTGGCACCAGCTAGCACCTCTGTGTTTTAAGGGTCTTTCAATGTTTCTAGAATAAGCCCT
TATTTTCAAGGGTTCATAACAGGCATAAAATCTCTTCTCCTGGCAAAAGCTGCTATGAAAAGCCTCAGCTTGGGAAGATAGATTTTTTTC
CCCCCAATTACAAAATCTAAGTATTTTGGCCCTTCAATTTGGAGGAGGGCAAAAGTTGGAAGTAAGAAGTTTTATTTTAAGTACTTTCAG
TGCTCAAAAAAATGCAATCACTGTGTTGTATATAATAGTTCATAGGTTGATCACTCATAATAATTGACTCTAAGGCTTTTATTAAGAAAA
CAGCAGAAAGATTAAATCTTGAATTAAGTCTGGGGGGAAATGGCCACTGCAGATGGAGTTTTAGAGTAGTAATGAAATTCTACCTAGAAT
GCAAAATTGGGTATATGAATTACATAGCATGTTGTTGGGATTTTTTTTAATGTGCAGAAGATCAAAGCTACTTGGAAGGAGTGCCTATAA
TTTGCCAGTAGCCACAGATTAAGATTATATCTTATATATCAGCAGATTAGCTTTAGCTTAGGGGGAGGGTGGGAAAGTTTGGGGGGGGGG
TTGTGAAGATTTAGGGGGACCTTGATAGAGAACTTTATAAACTTCTTTCTCTTTAATAAAGACTTGTCTTACACCGTGCTGCCATTAAAG
GCAGCTGTTCTAGAGTTTCAGTCACCTAAGTACACCCACAAAACAATATGAATATGGAGATCTTCCTTTACCCCTCAACTTTAATTTGCC
CAGTTATACCTCAGTGTTGTAGCAGTACTGTGATACCTGGCACAGTGCTTTGATCTTACGATGCCCTCTGTACTGACCTGAAGGAGACCT
AAGAGTCCTTTCCCTTTTTGAGTTTGAATCATAGCCTTGATGTGGTCTCTTGTTTTATGTCCTTGTTCCTAATGTAAAAGTGCTTAACTG
CTTCTTGGTTGTATTGGGTAGCATTGGGATAAGATTTTAACTGGGTATTCTTGAATTGCTTTTACAATAAACCAATTTTATAATCTTTAA
ATTTATCAACTTTTTACATTTGTGTTATTTTCAGTCAGGGCTTCTTAGATCTACTTATGGTTGATGGAGCACATTGATTTGGAGTTTCAG
ATCTTCCAAAGCACTATTTGTTGTAATAACTTTTCTAAATGTAGTGCCTTTAAAGGAAAAATGAACACAGGGAAGTGACTTTGCTACAAA
TAATGTTGCTGTGTTAAGTATTCATATTAAATACATGCCTTCTATATGGAACATGGCAGAAAGACTGAAAAATAACAGTAATTAATTGTG
TAATTCAGAATTCATACCAATCAGTGTTGAAACTCAAACATTGCAAAAGTGGGTGGCAATATTCAGTGCTTAACACTTTTCTAGCGTTGG
TACATCTGAGAAATGAGTGCTCAGGTGGATTTTATCCTCGCAAGCATGTTGTTATAAGAATTGTGGGTGTGCCTATCATAACAATTGTTT
TCTGTATCTTGAAAAAGTATTCTCCACATTTTAAATGTTTTATATTAGAGAATTCTTTAATGCACACTTGTCAAATATATATATATAGTA
CCAATGTTACCTTTTTATTTTTTGTTTTAGATGTAAGAGCATGCTCATATGTTAGGTACTTACATAAATTGTTACATTATTTTTTCTTAT

>24824_24824_2_EBF2-YAP1_EBF2_chr8_25890600_ENST00000520164_YAP1_chr11_102033186_ENST00000345877_length(amino acids)=447AA_BP=183
MFGIQDTLGRGPTLKEKSLGAEMDSVRSWVRNVGVVDANVAAQSGVALSRAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVD
FVENDKEQGNEKTNNGTHYKLQLLYSNGVRTEQDLYVRLIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPV
IIDSHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEK
ERLRLKQQELLRQVRPQELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFL

--------------------------------------------------------------
>24824_24824_3_EBF2-YAP1_EBF2_chr8_25890600_ENST00000520164_YAP1_chr11_102033186_ENST00000524575_length(transcript)=2244nt_BP=1089nt
ATTCATGGGGCCCGCGCGCGGCTGCAGCCGGGCTCCGTGGCGCTCGCAGCCACCGCCTCCTCTCGGCTCCAGGTCTTCCCCTTCTTTTTA
CAACTGATCCTGTTGGGGATTTTTTTTTTTTCTAAATTGGAACGGTGGGGAGGAGCAGGGAGGGGGGACCTGGAGGAAGGGGAGAGATTA
GGCAGCCATCAATTTCCTCCAGTTTCTCCCAGAACAGGTGATGCTTCTAAATTGTGATCACTTTCAGGAGGCAGCACTGCAGCTGGAAGG
ATGCGAGCGACCTAGGGTGGAGTGGCTGAGGCGGCAGATCTGAACTTGCGGAGGATAAGAACCCAAACTTTGACTACATCAGTCCGCACC
TCGCCAGTGAAGCAAAGGACGGGTTATCTTTTTTTTTTTTCTAAGACTCAAACTTGGGCACTTGATCCCTTTTCTTGGATTGCTTTGGAG
GAGACGATTTGCTGGCAACGTTGGGAACAGTCAGGACTGTGTTGTAACTCTTACTTTTAAAGCGACAGTAGAGGATCAGACTTTTTAAAT
GTTTGGAATTCAAGATACTTTAGGAAGAGGACCAACTCTGAAAGAGAAATCGCTGGGCGCGGAGATGGATTCGGTCAGGTCCTGGGTCCG
GAATGTCGGAGTGGTGGACGCTAATGTCGCCGCGCAGAGCGGGGTCGCCCTGTCCCGGGCCCACTTTGAGAAACAGCCTCCTTCCAACTT
GAGGAAATCCAACTTCTTTCACTTCGTCCTGGCGCTCTATGACAGGCAGGGCCAGCCGGTGGAGATCGAGCGGACGGCCTTCGTGGACTT
TGTGGAGAATGACAAAGAACAAGGCAACGAGAAGACCAACAACGGCACTCACTACAAGTTACAGCTCCTCTACAGCAACGGTGTCCGCAC
GGAACAGGACCTCTATGTCAGGCTCATCGACTCGGTCACCAAGCAGCCCATCGCTTACGAGGGACAGAATAAGAATCCGGAAATGTGCCG
AGTTCTCCTGACGCACGAAGTGATGTGTAGTCGATGCTGCGAAAAGAAAAGCTGTGGAAACCGAAATGAGACTCCATCGGACCCAGTCAT
AATTGACAGTCACATCGATCAGACAACAACATGGCAGGACCCCAGGAAGGCCATGCTGTCCCAGATGAACGTCACAGCCCCCACCAGTCC
ACCAGTGCAGCAGAATATGATGAACTCGGCTTCAGGTCCTCTTCCTGATGGATGGGAACAAGCCATGACTCAGGATGGAGAAATTTACTA
TATAAACCATAAGAACAAGACCACCTCTTGGCTAGACCCAAGGCTTGACCCTCGTTTTGCCATGAACCAGAGAATCAGTCAGAGTGCTCC
AGTGAAACAGCCACCACCCCTGGCTCCCCAGAGCCCACAGGGAGGCGTCATGGGTGGCAGCAACTCCAACCAGCAGCAACAGATGCGACT
GCAGCAACTGCAGATGGAGAAGGAGAGGCTGCGGCTGAAACAGCAAGAACTGCTTCGGCAGGCAATGCGGAATATCAATCCCAGCACAGC
AAATTCTCCAAAATGTCAGGAGTTAGCCCTGCGTAGCCAGTTACCAACACTGGAGCAGGATGGTGGGACTCAAAATCCAGTGTCTTCTCC
CGGGATGTCTCAGGAATTGAGAACAATGACGACCAATAGCTCAGATCCTTTCCTTAACAGTGGCACCTATCACTCTCGAGATGAGAGTAC
AGACAGTGGACTAAGCATGAGCAGCTACAGTGTCCCTCGAACCCCAGATGACTTCCTGAACAGTGTGGATGAGATGGATACAGGTGATAC
TATCAACCAAAGCACCCTGCCCTCACAGCAGAACCGTTTCCCAGACTACCTTGAAGCCATTCCTGGGACAAATGTGGACCTTGGAACACT
GGAAGGAGATGGAATGAACATAGAAGGAGAGGAGCTGATGCCAAGTCTGCAGGAAGCTTTGAGTTCTGACATCCTTAATGACATGGAGTC
TGTTTTGGCTGCCACCAAGCTAGATAAAGAAAGCTTTCTTACATGGTTATAGAGCCCTCAGGCAGACTGAATTCTAAATCTGTGAAGGAT
CTAAGGAGACACATGCACCGGAAATTTCCATAAGCCAGTTGCAGTTTTCAGGCTAATACAGAAAAAGATGAACAAACGTCCAGCAAGATA

>24824_24824_3_EBF2-YAP1_EBF2_chr8_25890600_ENST00000520164_YAP1_chr11_102033186_ENST00000524575_length(amino acids)=497AA_BP=183
MFGIQDTLGRGPTLKEKSLGAEMDSVRSWVRNVGVVDANVAAQSGVALSRAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVD
FVENDKEQGNEKTNNGTHYKLQLLYSNGVRTEQDLYVRLIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPV
IIDSHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASGPLPDGWEQAMTQDGEIYYINHKNKTTSWLDPRLDPRFAMNQRISQSA
PVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKERLRLKQQELLRQAMRNINPSTANSPKCQELALRSQLPTLEQDGGTQNPVSS
PGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGT

--------------------------------------------------------------
>24824_24824_4_EBF2-YAP1_EBF2_chr8_25890600_ENST00000520164_YAP1_chr11_102033186_ENST00000526343_length(transcript)=2522nt_BP=1089nt
ATTCATGGGGCCCGCGCGCGGCTGCAGCCGGGCTCCGTGGCGCTCGCAGCCACCGCCTCCTCTCGGCTCCAGGTCTTCCCCTTCTTTTTA
CAACTGATCCTGTTGGGGATTTTTTTTTTTTCTAAATTGGAACGGTGGGGAGGAGCAGGGAGGGGGGACCTGGAGGAAGGGGAGAGATTA
GGCAGCCATCAATTTCCTCCAGTTTCTCCCAGAACAGGTGATGCTTCTAAATTGTGATCACTTTCAGGAGGCAGCACTGCAGCTGGAAGG
ATGCGAGCGACCTAGGGTGGAGTGGCTGAGGCGGCAGATCTGAACTTGCGGAGGATAAGAACCCAAACTTTGACTACATCAGTCCGCACC
TCGCCAGTGAAGCAAAGGACGGGTTATCTTTTTTTTTTTTCTAAGACTCAAACTTGGGCACTTGATCCCTTTTCTTGGATTGCTTTGGAG
GAGACGATTTGCTGGCAACGTTGGGAACAGTCAGGACTGTGTTGTAACTCTTACTTTTAAAGCGACAGTAGAGGATCAGACTTTTTAAAT
GTTTGGAATTCAAGATACTTTAGGAAGAGGACCAACTCTGAAAGAGAAATCGCTGGGCGCGGAGATGGATTCGGTCAGGTCCTGGGTCCG
GAATGTCGGAGTGGTGGACGCTAATGTCGCCGCGCAGAGCGGGGTCGCCCTGTCCCGGGCCCACTTTGAGAAACAGCCTCCTTCCAACTT
GAGGAAATCCAACTTCTTTCACTTCGTCCTGGCGCTCTATGACAGGCAGGGCCAGCCGGTGGAGATCGAGCGGACGGCCTTCGTGGACTT
TGTGGAGAATGACAAAGAACAAGGCAACGAGAAGACCAACAACGGCACTCACTACAAGTTACAGCTCCTCTACAGCAACGGTGTCCGCAC
GGAACAGGACCTCTATGTCAGGCTCATCGACTCGGTCACCAAGCAGCCCATCGCTTACGAGGGACAGAATAAGAATCCGGAAATGTGCCG
AGTTCTCCTGACGCACGAAGTGATGTGTAGTCGATGCTGCGAAAAGAAAAGCTGTGGAAACCGAAATGAGACTCCATCGGACCCAGTCAT
AATTGACAGTCACATCGATCAGACAACAACATGGCAGGACCCCAGGAAGGCCATGCTGTCCCAGATGAACGTCACAGCCCCCACCAGTCC
ACCAGTGCAGCAGAATATGATGAACTCGGCTTCAGCCATGAACCAGAGAATCAGTCAGAGTGCTCCAGTGAAACAGCCACCACCCCTGGC
TCCCCAGAGCCCACAGGGAGGCGTCATGGGTGGCAGCAACTCCAACCAGCAGCAACAGATGCGACTGCAGCAACTGCAGATGGAGAAGGA
GAGGCTGCGGCTGAAACAGCAAGAACTGCTTCGGCAGGAGTTAGCCCTGCGTAGCCAGTTACCAACACTGGAGCAGGATGGTGGGACTCA
AAATCCAGTGTCTTCTCCCGGGATGTCTCAGGAATTGAGAACAATGACGACCAATAGCTCAGATCCTTTCCTTAACAGTGGCACCTATCA
CTCTCGAGATGAGAGTACAGACAGTGGACTAAGCATGAGCAGCTACAGTGTCCCTCGAACCCCAGATGACTTCCTGAACAGTGTGGATGA
GATGGATACAGGTGATACTATCAACCAAAGCACCCTGCCCTCACAGCAGAACCGTTTCCCAGACTACCTTGAAGCCATTCCTGGGACAAA
TGTGGACCTTGGAACACTGGAAGGAGATGGAATGAACATAGAAGGAGAGGAGCTGATGCCAAGTCTGCAGGAAGCTTTGAGTTCTGACAT
CCTTAATGACATGGAGTCTGTTTTGGCTGCCACCAAGCTAGATAAAGAAAGCTTTCTTACATGGTTATAGAGCCCTCAGGCAGACTGAAT
TCTAAATCTGTGAAGGATCTAAGGAGACACATGCACCGGAAATTTCCATAAGCCAGTTGCAGTTTTCAGGCTAATACAGAAAAAGATGAA
CAAACGTCCAGCAAGATACTTTAATCCTCTATTTTGCTCTTCCTTGTCCATTGCTGCTGTTAATGTATTGCTGACCTCTTTCACAGTTGG
CTCTAAAGAATCAAAAGAAAAAAACTTTTTATTTCTTTTGCTATTAAAACTACTGTTCATTTTGGGGGCTGGGGGAAGTGAGCCTGTTTG
GATGATGGATGCCATTCCTTTTGCCCAGTTAAATGTTCACCAATCATTTTAACTAAATACTCAGACTTAGAAGTCAGATGCTTCATGTCA
CAGCATTTAGTTTGTTCAACAGTTGTTTCTTCAGCTTCCTTTGTCCAGTGGAAAAACATGATTTACTGGTCTGACAAGCCAAAAATGTTA
TATCTGATATTAAATACTTAATGCTGATTTGAAGAGATAGCTGAAACCAAGGCTGAAGACTGTTTTACTTTCAGTATTTTCTTTTCCTCC
TAGTGCTATCATTAGTCACATAATGACCTTGATTTTATTTTAGGAGCTTATAAGGCATGAGACAATTTCCATATAAATATATTAATTATT

>24824_24824_4_EBF2-YAP1_EBF2_chr8_25890600_ENST00000520164_YAP1_chr11_102033186_ENST00000526343_length(amino acids)=443AA_BP=183
MFGIQDTLGRGPTLKEKSLGAEMDSVRSWVRNVGVVDANVAAQSGVALSRAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVD
FVENDKEQGNEKTNNGTHYKLQLLYSNGVRTEQDLYVRLIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPV
IIDSHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASAMNQRISQSAPVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEK
ERLRLKQQELLRQELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVD

--------------------------------------------------------------
>24824_24824_5_EBF2-YAP1_EBF2_chr8_25890600_ENST00000520164_YAP1_chr11_102033186_ENST00000531439_length(transcript)=2007nt_BP=1089nt
ATTCATGGGGCCCGCGCGCGGCTGCAGCCGGGCTCCGTGGCGCTCGCAGCCACCGCCTCCTCTCGGCTCCAGGTCTTCCCCTTCTTTTTA
CAACTGATCCTGTTGGGGATTTTTTTTTTTTCTAAATTGGAACGGTGGGGAGGAGCAGGGAGGGGGGACCTGGAGGAAGGGGAGAGATTA
GGCAGCCATCAATTTCCTCCAGTTTCTCCCAGAACAGGTGATGCTTCTAAATTGTGATCACTTTCAGGAGGCAGCACTGCAGCTGGAAGG
ATGCGAGCGACCTAGGGTGGAGTGGCTGAGGCGGCAGATCTGAACTTGCGGAGGATAAGAACCCAAACTTTGACTACATCAGTCCGCACC
TCGCCAGTGAAGCAAAGGACGGGTTATCTTTTTTTTTTTTCTAAGACTCAAACTTGGGCACTTGATCCCTTTTCTTGGATTGCTTTGGAG
GAGACGATTTGCTGGCAACGTTGGGAACAGTCAGGACTGTGTTGTAACTCTTACTTTTAAAGCGACAGTAGAGGATCAGACTTTTTAAAT
GTTTGGAATTCAAGATACTTTAGGAAGAGGACCAACTCTGAAAGAGAAATCGCTGGGCGCGGAGATGGATTCGGTCAGGTCCTGGGTCCG
GAATGTCGGAGTGGTGGACGCTAATGTCGCCGCGCAGAGCGGGGTCGCCCTGTCCCGGGCCCACTTTGAGAAACAGCCTCCTTCCAACTT
GAGGAAATCCAACTTCTTTCACTTCGTCCTGGCGCTCTATGACAGGCAGGGCCAGCCGGTGGAGATCGAGCGGACGGCCTTCGTGGACTT
TGTGGAGAATGACAAAGAACAAGGCAACGAGAAGACCAACAACGGCACTCACTACAAGTTACAGCTCCTCTACAGCAACGGTGTCCGCAC
GGAACAGGACCTCTATGTCAGGCTCATCGACTCGGTCACCAAGCAGCCCATCGCTTACGAGGGACAGAATAAGAATCCGGAAATGTGCCG
AGTTCTCCTGACGCACGAAGTGATGTGTAGTCGATGCTGCGAAAAGAAAAGCTGTGGAAACCGAAATGAGACTCCATCGGACCCAGTCAT
AATTGACAGTCACATCGATCAGACAACAACATGGCAGGACCCCAGGAAGGCCATGCTGTCCCAGATGAACGTCACAGCCCCCACCAGTCC
ACCAGTGCAGCAGAATATGATGAACTCGGCTTCAGGTCCTCTTCCTGATGGATGGGAACAAGCCATGACTCAGGATGGAGAAATTTACTA
TATAAACCATAAGAACAAGACCACCTCTTGGCTAGACCCAAGGCTTGACCCTCGTTTTGCCATGAACCAGAGAATCAGTCAGAGTGCTCC
AGTGAAACAGCCACCACCCCTGGCTCCCCAGAGCCCACAGGGAGGCGTCATGGGTGGCAGCAACTCCAACCAGCAGCAACAGATGCGACT
GCAGCAACTGCAGATGGAGAAGGAGAGGCTGCGGCTGAAACAGCAAGAACTGCTTCGGCAGGAGTTAGCCCTGCGTAGCCAGTTACCAAC
ACTGGAGCAGGATGGTGGGACTCAAAATCCAGTGTCTTCTCCCGGGATGTCTCAGGAATTGAGAACAATGACGACCAATAGCTCAGATCC
TTTCCTTAACAGTGGCACCTATCACTCTCGAGATGAGAGTACAGACAGTGGACTAAGCATGAGCAGCTACAGTGTCCCTCGAACCCCAGA
TGACTTCCTGAACAGTGTGGATGAGATGGATACAGGTGATACTATCAACCAAAGCACCCTGCCCTCACAGCAGAACCGTTTCCCAGACTA
CCTTGAAGCCATTCCTGGGACAAATGTGGACCTTGGAACACTGGAAGGAGATGGAATGAACATAGAAGGAGAGGAGCTGATGCCAAGTCT
GCAGGAAGCTTTGAGTTCTGACATCCTTAATGACATGGAGTCTGTTTTGGCTGCCACCAAGCTAGATAAAGAAAGCTTTCTTACATGGTT

>24824_24824_5_EBF2-YAP1_EBF2_chr8_25890600_ENST00000520164_YAP1_chr11_102033186_ENST00000531439_length(amino acids)=481AA_BP=183
MFGIQDTLGRGPTLKEKSLGAEMDSVRSWVRNVGVVDANVAAQSGVALSRAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVD
FVENDKEQGNEKTNNGTHYKLQLLYSNGVRTEQDLYVRLIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPV
IIDSHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASGPLPDGWEQAMTQDGEIYYINHKNKTTSWLDPRLDPRFAMNQRISQSA
PVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKERLRLKQQELLRQELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTTNSSD
PFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEELMPS

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>24824_24824_6_EBF2-YAP1_EBF2_chr8_25890600_ENST00000520164_YAP1_chr11_102033186_ENST00000537274_length(transcript)=5479nt_BP=1089nt
ATTCATGGGGCCCGCGCGCGGCTGCAGCCGGGCTCCGTGGCGCTCGCAGCCACCGCCTCCTCTCGGCTCCAGGTCTTCCCCTTCTTTTTA
CAACTGATCCTGTTGGGGATTTTTTTTTTTTCTAAATTGGAACGGTGGGGAGGAGCAGGGAGGGGGGACCTGGAGGAAGGGGAGAGATTA
GGCAGCCATCAATTTCCTCCAGTTTCTCCCAGAACAGGTGATGCTTCTAAATTGTGATCACTTTCAGGAGGCAGCACTGCAGCTGGAAGG
ATGCGAGCGACCTAGGGTGGAGTGGCTGAGGCGGCAGATCTGAACTTGCGGAGGATAAGAACCCAAACTTTGACTACATCAGTCCGCACC
TCGCCAGTGAAGCAAAGGACGGGTTATCTTTTTTTTTTTTCTAAGACTCAAACTTGGGCACTTGATCCCTTTTCTTGGATTGCTTTGGAG
GAGACGATTTGCTGGCAACGTTGGGAACAGTCAGGACTGTGTTGTAACTCTTACTTTTAAAGCGACAGTAGAGGATCAGACTTTTTAAAT
GTTTGGAATTCAAGATACTTTAGGAAGAGGACCAACTCTGAAAGAGAAATCGCTGGGCGCGGAGATGGATTCGGTCAGGTCCTGGGTCCG
GAATGTCGGAGTGGTGGACGCTAATGTCGCCGCGCAGAGCGGGGTCGCCCTGTCCCGGGCCCACTTTGAGAAACAGCCTCCTTCCAACTT
GAGGAAATCCAACTTCTTTCACTTCGTCCTGGCGCTCTATGACAGGCAGGGCCAGCCGGTGGAGATCGAGCGGACGGCCTTCGTGGACTT
TGTGGAGAATGACAAAGAACAAGGCAACGAGAAGACCAACAACGGCACTCACTACAAGTTACAGCTCCTCTACAGCAACGGTGTCCGCAC
GGAACAGGACCTCTATGTCAGGCTCATCGACTCGGTCACCAAGCAGCCCATCGCTTACGAGGGACAGAATAAGAATCCGGAAATGTGCCG
AGTTCTCCTGACGCACGAAGTGATGTGTAGTCGATGCTGCGAAAAGAAAAGCTGTGGAAACCGAAATGAGACTCCATCGGACCCAGTCAT
AATTGACAGTCACATCGATCAGACAACAACATGGCAGGACCCCAGGAAGGCCATGCTGTCCCAGATGAACGTCACAGCCCCCACCAGTCC
ACCAGTGCAGCAGAATATGATGAACTCGGCTTCAGGTCCTCTTCCTGATGGATGGGAACAAGCCATGACTCAGGATGGAGAAATTTACTA
TATAAACCATAAGAACAAGACCACCTCTTGGCTAGACCCAAGGCTTGACCCTCGTTTTGCCATGAACCAGAGAATCAGTCAGAGTGCTCC
AGTGAAACAGCCACCACCCCTGGCTCCCCAGAGCCCACAGGGAGGCGTCATGGGTGGCAGCAACTCCAACCAGCAGCAACAGATGCGACT
GCAGCAACTGCAGATGGAGAAGGAGAGGCTGCGGCTGAAACAGCAAGAACTGCTTCGGCAGGTGAGGCCACAGGAGTTAGCCCTGCGTAG
CCAGTTACCAACACTGGAGCAGGATGGTGGGACTCAAAATCCAGTGTCTTCTCCCGGGATGTCTCAGGAATTGAGAACAATGACGACCAA
TAGCTCAGATCCTTTCCTTAACAGTGGCACCTATCACTCTCGAGATGAGAGTACAGACAGTGGACTAAGCATGAGCAGCTACAGTGTCCC
TCGAACCCCAGATGACTTCCTGAACAGTGTGGATGAGATGGATACAGGTGATACTATCAACCAAAGCACCCTGCCCTCACAGCAGAACCG
TTTCCCAGACTACCTTGAAGCCATTCCTGGGACAAATGTGGACCTTGGAACACTGGAAGGAGATGGAATGAACATAGAAGGAGAGGAGCT
GATGCCAAGTCTGCAGGAAGCTTTGAGTTCTGACATCCTTAATGACATGGAGTCTGTTTTGGCTGCCACCAAGCTAGATAAAGAAAGCTT
TCTTACATGGTTATAGAGCCCTCAGGCAGACTGAATTCTAAATCTGTGAAGGATCTAAGGAGACACATGCACCGGAAATTTCCATAAGCC
AGTTGCAGTTTTCAGGCTAATACAGAAAAAGATGAACAAACGTCCAGCAAGATACTTTAATCCTCTATTTTGCTCTTCCTTGTCCATTGC
TGCTGTTAATGTATTGCTGACCTCTTTCACAGTTGGCTCTAAAGAATCAAAAGAAAAAAACTTTTTATTTCTTTTGCTATTAAAACTACT
GTTCATTTTGGGGGCTGGGGGAAGTGAGCCTGTTTGGATGATGGATGCCATTCCTTTTGCCCAGTTAAATGTTCACCAATCATTTTAACT
AAATACTCAGACTTAGAAGTCAGATGCTTCATGTCACAGCATTTAGTTTGTTCAACAGTTGTTTCTTCAGCTTCCTTTGTCCAGTGGAAA
AACATGATTTACTGGTCTGACAAGCCAAAAATGTTATATCTGATATTAAATACTTAATGCTGATTTGAAGAGATAGCTGAAACCAAGGCT
GAAGACTGTTTTACTTTCAGTATTTTCTTTTCCTCCTAGTGCTATCATTAGTCACATAATGACCTTGATTTTATTTTAGGAGCTTATAAG
GCATGAGACAATTTCCATATAAATATATTAATTATTGCCACATACTCTAATATAGATTTTGGTGGATAATTTTGTGGGTGTGCATTTTGT
TCTGTTTTGTTGGGTTTTTTGTTTTTTTTGTTTTTGGCAGGGTCGGTGGGGGGGTTGGTTGGTTGGTTGGTTTTGTCGGAACCTAGGCAA
ATGACCATATTAGTGAATCTGTTAATAGTTGTAGCTTGGGATGGTTATTGTAGTTGTTTTGGTAAAATCTTCATTTCCTGGTTTTTTTTA
CCACCTTATTTAAATCTCGATTATCTGCTCTCTCTTTTATATACATACACACACCCAAACATAACATTTATAATAGTGTGGTAGTGGAAT
GTATCCTTTTTTAGGTTTCCCTGCTTTCCAGTTAATTTTTAAAATGGTAGCGCTTTGTATGCATTTAGAATACATGACTAGTAGTTTATA
TTTCACTGGTAGTTTAAATCTGGTTGGGGCAGTCTGCAGATGTTTGAAGTAGTTTAGTGTTCTAGAAAGAGCTATTACTGTGGATAGTGC
CTAGGGGAGTGCTCCACGCCCTCTGGGCATACGGTAGATATTATCTGATGAATTGGAAAGGAGCAAACCAGAAATGGCTTTATTTTCTCC
CTTGGACTAATTTTTAAGTCTCGATTGGAATTCAGTGAGTAGGTTCATAATGTGCATGACAGAAATAAGCTTTATAGTGGTTTACCTTCA
TTTAGCTTTGGAAGTTTTCTTTGCCTTAGTTTTGGAAGTAAATTCTAGTTTGTAGTTCTCATTTGTAATGAACACATTAACGACTAGATT
AAAATATTGCCTTCAAGATTGTTCTTACTTACAAGACTTGCTCCTACTTCTATGCTGAAAATTGACCCTGGATAGAATACTATAAGGTTT
TGAGTTAGCTGGAAAAGTGATCAGATTAATAAATGTATATTGGTAGTTGAATTTAGCAAAGAAATAGAGATAATCATGATTATACCTTTA
TTTTTACAGGAAGAGATGATGTAACTAGAGTATGTGTCTACAGGAGTAATAATGGTTTCCAAAGAGTATTTTTTAAAGGAACAAAACGAG
CATGAATTAACTCTTCAATATAAGCTATGAAGTAATAGTTGGTTGTGAATTAAAGTGGCACCAGCTAGCACCTCTGTGTTTTAAGGGTCT
TTCAATGTTTCTAGAATAAGCCCTTATTTTCAAGGGTTCATAACAGGCATAAAATCTCTTCTCCTGGCAAAAGCTGCTATGAAAAGCCTC
AGCTTGGGAAGATAGATTTTTTTCCCCCCAATTACAAAATCTAAGTATTTTGGCCCTTCAATTTGGAGGAGGGCAAAAGTTGGAAGTAAG
AAGTTTTATTTTAAGTACTTTCAGTGCTCAAAAAAATGCAATCACTGTGTTGTATATAATAGTTCATAGGTTGATCACTCATAATAATTG
ACTCTAAGGCTTTTATTAAGAAAACAGCAGAAAGATTAAATCTTGAATTAAGTCTGGGGGGAAATGGCCACTGCAGATGGAGTTTTAGAG
TAGTAATGAAATTCTACCTAGAATGCAAAATTGGGTATATGAATTACATAGCATGTTGTTGGGATTTTTTTTAATGTGCAGAAGATCAAA
GCTACTTGGAAGGAGTGCCTATAATTTGCCAGTAGCCACAGATTAAGATTATATCTTATATATCAGCAGATTAGCTTTAGCTTAGGGGGA
GGGTGGGAAAGTTTGGGGGGGGGGTTGTGAAGATTTAGGGGGACCTTGATAGAGAACTTTATAAACTTCTTTCTCTTTAATAAAGACTTG
TCTTACACCGTGCTGCCATTAAAGGCAGCTGTTCTAGAGTTTCAGTCACCTAAGTACACCCACAAAACAATATGAATATGGAGATCTTCC
TTTACCCCTCAACTTTAATTTGCCCAGTTATACCTCAGTGTTGTAGCAGTACTGTGATACCTGGCACAGTGCTTTGATCTTACGATGCCC
TCTGTACTGACCTGAAGGAGACCTAAGAGTCCTTTCCCTTTTTGAGTTTGAATCATAGCCTTGATGTGGTCTCTTGTTTTATGTCCTTGT
TCCTAATGTAAAAGTGCTTAACTGCTTCTTGGTTGTATTGGGTAGCATTGGGATAAGATTTTAACTGGGTATTCTTGAATTGCTTTTACA
ATAAACCAATTTTATAATCTTTAAATTTATCAACTTTTTACATTTGTGTTATTTTCAGTCAGGGCTTCTTAGATCTACTTATGGTTGATG
GAGCACATTGATTTGGAGTTTCAGATCTTCCAAAGCACTATTTGTTGTAATAACTTTTCTAAATGTAGTGCCTTTAAAGGAAAAATGAAC
ACAGGGAAGTGACTTTGCTACAAATAATGTTGCTGTGTTAAGTATTCATATTAAATACATGCCTTCTATATGGAACATGGCAGAAAGACT
GAAAAATAACAGTAATTAATTGTGTAATTCAGAATTCATACCAATCAGTGTTGAAACTCAAACATTGCAAAAGTGGGTGGCAATATTCAG
TGCTTAACACTTTTCTAGCGTTGGTACATCTGAGAAATGAGTGCTCAGGTGGATTTTATCCTCGCAAGCATGTTGTTATAAGAATTGTGG
GTGTGCCTATCATAACAATTGTTTTCTGTATCTTGAAAAAGTATTCTCCACATTTTAAATGTTTTATATTAGAGAATTCTTTAATGCACA
CTTGTCAAATATATATATATAGTACCAATGTTACCTTTTTATTTTTTGTTTTAGATGTAAGAGCATGCTCATATGTTAGGTACTTACATA

>24824_24824_6_EBF2-YAP1_EBF2_chr8_25890600_ENST00000520164_YAP1_chr11_102033186_ENST00000537274_length(amino acids)=485AA_BP=183
MFGIQDTLGRGPTLKEKSLGAEMDSVRSWVRNVGVVDANVAAQSGVALSRAHFEKQPPSNLRKSNFFHFVLALYDRQGQPVEIERTAFVD
FVENDKEQGNEKTNNGTHYKLQLLYSNGVRTEQDLYVRLIDSVTKQPIAYEGQNKNPEMCRVLLTHEVMCSRCCEKKSCGNRNETPSDPV
IIDSHIDQTTTWQDPRKAMLSQMNVTAPTSPPVQQNMMNSASGPLPDGWEQAMTQDGEIYYINHKNKTTSWLDPRLDPRFAMNQRISQSA
PVKQPPPLAPQSPQGGVMGGSNSNQQQQMRLQQLQMEKERLRLKQQELLRQVRPQELALRSQLPTLEQDGGTQNPVSSPGMSQELRTMTT
NSSDPFLNSGTYHSRDESTDSGLSMSSYSVPRTPDDFLNSVDEMDTGDTINQSTLPSQQNRFPDYLEAIPGTNVDLGTLEGDGMNIEGEE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for EBF2-YAP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneEBF2chr8:25890600chr11:102033186ENST00000520164-61662_65183.66666666666666576.0DNA


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneEBF2chr8:25890600chr11:102033186ENST00000520164-616196_203183.66666666666666576.0DNA
HgeneEBF2chr8:25890600chr11:102033186ENST00000520164-616235_238183.66666666666666576.0DNA


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for EBF2-YAP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for EBF2-YAP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource