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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:EGFR-SEPT14 (FusionGDB2 ID:25482)

Fusion Gene Summary for EGFR-SEPT14

check button Fusion gene summary
Fusion gene informationFusion gene name: EGFR-SEPT14
Fusion gene ID: 25482
HgeneTgene
Gene symbol

EGFR

SEPT14

Gene ID

1956

346288

Gene nameepidermal growth factor receptorseptin 14
SynonymsERBB|ERBB1|HER1|NISBD2|PIG61|mENASEPT14
Cytomap

7p11.2

7p11.2

Type of geneprotein-codingprotein-coding
Descriptionepidermal growth factor receptoravian erythroblastic leukemia viral (v-erb-b) oncogene homologcell growth inhibiting protein 40cell proliferation-inducing protein 61epidermal growth factor receptor tyrosine kinase domainerb-b2 receptor tyrosine kinasseptin-14
Modification date2020032920200313
UniProtAcc

P00533

.
Ensembl transtripts involved in fusion geneENST00000463948, ENST00000275493, 
ENST00000342916, ENST00000344576, 
ENST00000420316, ENST00000442591, 
ENST00000454757, ENST00000455089, 
ENST00000388975, ENST00000477628, 
Fusion gene scores* DoF score41 X 25 X 14=143506 X 5 X 5=150
# samples 5313
** MAII scorelog2(53/14350*10)=-4.75891456699985
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/150*10)=-0.206450877467426
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EGFR [Title/Abstract] AND SEPT14 [Title/Abstract] AND fusion [Title/Abstract]

Detection of EGFR-SEPT14 fusion in cell-free DNA of a patient with advanced gastric cancer: A case report (pmid: 33969073)
Most frequent breakpointEGFR(55268106)-SEPT14(55863785), # samples:24
Anticipated loss of major functional domain due to fusion event.EGFR-SEPT14 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
EGFR-SEPT14 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
EGFR-SEPT14 seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneEGFR

GO:0001934

positive regulation of protein phosphorylation

20551055

HgeneEGFR

GO:0007165

signal transduction

10572067

HgeneEGFR

GO:0007166

cell surface receptor signaling pathway

7736574

HgeneEGFR

GO:0007173

epidermal growth factor receptor signaling pathway

7736574|12435727

HgeneEGFR

GO:0008283

cell proliferation

17115032

HgeneEGFR

GO:0008284

positive regulation of cell proliferation

7736574

HgeneEGFR

GO:0010750

positive regulation of nitric oxide mediated signal transduction

12828935

HgeneEGFR

GO:0018108

peptidyl-tyrosine phosphorylation

22732145

HgeneEGFR

GO:0030307

positive regulation of cell growth

15467833

HgeneEGFR

GO:0042177

negative regulation of protein catabolic process

17115032

HgeneEGFR

GO:0042327

positive regulation of phosphorylation

15082764

HgeneEGFR

GO:0043406

positive regulation of MAP kinase activity

10572067

HgeneEGFR

GO:0045739

positive regulation of DNA repair

17115032

HgeneEGFR

GO:0045740

positive regulation of DNA replication

17115032

HgeneEGFR

GO:0045944

positive regulation of transcription by RNA polymerase II

20551055

HgeneEGFR

GO:0050679

positive regulation of epithelial cell proliferation

10572067

HgeneEGFR

GO:0050999

regulation of nitric-oxide synthase activity

12828935

HgeneEGFR

GO:0070141

response to UV-A

18483258

HgeneEGFR

GO:0070374

positive regulation of ERK1 and ERK2 cascade

20551055

HgeneEGFR

GO:0071392

cellular response to estradiol stimulus

20551055

HgeneEGFR

GO:1900020

positive regulation of protein kinase C activity

22732145

HgeneEGFR

GO:1903078

positive regulation of protein localization to plasma membrane

22732145


check buttonFusion gene breakpoints across EGFR (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SEPT14 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-02-2485-01AEGFRchr7

55268106

+SEPT14chr7

55886916

-
ChimerDB4GBMTCGA-06-0187-01AEGFRchr7

55268106

+SEPT14chr7

55863785

-
ChimerDB4GBMTCGA-06-0211-01AEGFRchr7

55087058

+SEPT14chr7

55886916

-
ChimerDB4GBMTCGA-06-0211-01BEGFRchr7

55087058

+SEPT14chr7

55886916

-
ChimerDB4GBMTCGA-06-0750-01AEGFRchr7

55268106

-SEPT14chr7

55863785

-
ChimerDB4GBMTCGA-06-0750-01AEGFRchr7

55268106

+SEPT14chr7

55863785

-
ChimerDB4GBMTCGA-06-2557-01AEGFRchr7

55268106

+SEPT14chr7

55863785

-
ChimerDB4GBMTCGA-06-A6S1-01AEGFRchr7

55268106

+SEPT14chr7

55863785

-
ChimerDB4GBMTCGA-14-1825-01AEGFRchr7

55268106

+SEPT14chr7

55863785

-
ChimerDB4GBMTCGA-27-1837-01AEGFRchr7

55268106

-SEPT14chr7

55863785

-
ChimerDB4GBMTCGA-27-1837-01AEGFRchr7

55268106

+SEPT14chr7

55863785

-
ChimerDB4GBMTCGA-28-1747-01CEGFRchr7

55268106

-SEPT14chr7

55863785

-
ChimerDB4GBMTCGA-28-1747-01CEGFRchr7

55268106

+SEPT14chr7

55863785

-
ChimerDB4GBMTCGA-28-2513-01AEGFRchr7

55268106

-SEPT14chr7

55863785

-
ChimerDB4GBMTCGA-28-2513-01AEGFRchr7

55268106

+SEPT14chr7

55863785

-
ChimerDB4GBMTCGA-32-5222-01AEGFRchr7

55268106

-SEPT14chr7

55863785

-
ChimerDB4GBMTCGA-32-5222-01AEGFRchr7

55268106

+SEPT14chr7

55863785

-
ChimerDB4HNSCTCGA-CR-7368-01AEGFRchr7

55087058

-SEPT14chr7

55874951

-
ChimerDB4HNSCTCGA-CR-7368-01AEGFRchr7

55087058

+SEPT14chr7

55874951

-
ChimerDB4LGGTCGA-DU-5852-01AEGFRchr7

55270318

+SEPT14chr7

55863785

-
ChimerDB4LGGTCGA-DU-6406-01AEGFRchr7

55268106

-SEPT14chr7

55863785

-
ChimerDB4LGGTCGA-DU-6406-01AEGFRchr7

55268106

+SEPT14chr7

55863785

-
ChimerDB4LGGTCGA-DU-6406EGFRchr7

55268106

+SEPT14chr7

55863785

-
ChimerDB4LGGTCGA-DU-6407-01AEGFRchr7

55268106

+SEPT14chr7

55863785

-


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Fusion Gene ORF analysis for EGFR-SEPT14

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000463948ENST00000388975EGFRchr7

55087058

+SEPT14chr7

55886916

-
3UTR-3CDSENST00000463948ENST00000388975EGFRchr7

55087058

+SEPT14chr7

55874951

-
3UTR-intronENST00000463948ENST00000477628EGFRchr7

55087058

+SEPT14chr7

55886916

-
3UTR-intronENST00000463948ENST00000477628EGFRchr7

55087058

+SEPT14chr7

55874951

-
5CDS-intronENST00000275493ENST00000477628EGFRchr7

55268106

+SEPT14chr7

55886916

-
5CDS-intronENST00000275493ENST00000477628EGFRchr7

55087058

+SEPT14chr7

55886916

-
5CDS-intronENST00000275493ENST00000477628EGFRchr7

55268106

+SEPT14chr7

55863785

-
5CDS-intronENST00000275493ENST00000477628EGFRchr7

55087058

+SEPT14chr7

55874951

-
5CDS-intronENST00000275493ENST00000477628EGFRchr7

55270318

+SEPT14chr7

55863785

-
5CDS-intronENST00000342916ENST00000477628EGFRchr7

55087058

+SEPT14chr7

55886916

-
5CDS-intronENST00000342916ENST00000477628EGFRchr7

55087058

+SEPT14chr7

55874951

-
5CDS-intronENST00000344576ENST00000477628EGFRchr7

55087058

+SEPT14chr7

55886916

-
5CDS-intronENST00000344576ENST00000477628EGFRchr7

55087058

+SEPT14chr7

55874951

-
5CDS-intronENST00000420316ENST00000477628EGFRchr7

55087058

+SEPT14chr7

55886916

-
5CDS-intronENST00000420316ENST00000477628EGFRchr7

55087058

+SEPT14chr7

55874951

-
5CDS-intronENST00000442591ENST00000477628EGFRchr7

55087058

+SEPT14chr7

55886916

-
5CDS-intronENST00000442591ENST00000477628EGFRchr7

55087058

+SEPT14chr7

55874951

-
5CDS-intronENST00000454757ENST00000477628EGFRchr7

55268106

+SEPT14chr7

55886916

-
5CDS-intronENST00000454757ENST00000477628EGFRchr7

55268106

+SEPT14chr7

55863785

-
5CDS-intronENST00000454757ENST00000477628EGFRchr7

55270318

+SEPT14chr7

55863785

-
5CDS-intronENST00000455089ENST00000477628EGFRchr7

55268106

+SEPT14chr7

55886916

-
5CDS-intronENST00000455089ENST00000477628EGFRchr7

55087058

+SEPT14chr7

55886916

-
5CDS-intronENST00000455089ENST00000477628EGFRchr7

55268106

+SEPT14chr7

55863785

-
5CDS-intronENST00000455089ENST00000477628EGFRchr7

55087058

+SEPT14chr7

55874951

-
5CDS-intronENST00000455089ENST00000477628EGFRchr7

55270318

+SEPT14chr7

55863785

-
Frame-shiftENST00000275493ENST00000388975EGFRchr7

55087058

+SEPT14chr7

55886916

-
Frame-shiftENST00000275493ENST00000388975EGFRchr7

55268106

+SEPT14chr7

55863785

-
Frame-shiftENST00000275493ENST00000388975EGFRchr7

55270318

+SEPT14chr7

55863785

-
Frame-shiftENST00000342916ENST00000388975EGFRchr7

55087058

+SEPT14chr7

55886916

-
Frame-shiftENST00000344576ENST00000388975EGFRchr7

55087058

+SEPT14chr7

55886916

-
Frame-shiftENST00000420316ENST00000388975EGFRchr7

55087058

+SEPT14chr7

55886916

-
Frame-shiftENST00000442591ENST00000388975EGFRchr7

55087058

+SEPT14chr7

55886916

-
Frame-shiftENST00000454757ENST00000388975EGFRchr7

55268106

+SEPT14chr7

55863785

-
Frame-shiftENST00000454757ENST00000388975EGFRchr7

55270318

+SEPT14chr7

55863785

-
Frame-shiftENST00000455089ENST00000388975EGFRchr7

55087058

+SEPT14chr7

55886916

-
Frame-shiftENST00000455089ENST00000388975EGFRchr7

55268106

+SEPT14chr7

55863785

-
In-frameENST00000275493ENST00000388975EGFRchr7

55268106

+SEPT14chr7

55886916

-
In-frameENST00000275493ENST00000388975EGFRchr7

55087058

+SEPT14chr7

55874951

-
In-frameENST00000342916ENST00000388975EGFRchr7

55087058

+SEPT14chr7

55874951

-
In-frameENST00000344576ENST00000388975EGFRchr7

55087058

+SEPT14chr7

55874951

-
In-frameENST00000420316ENST00000388975EGFRchr7

55087058

+SEPT14chr7

55874951

-
In-frameENST00000442591ENST00000388975EGFRchr7

55087058

+SEPT14chr7

55874951

-
In-frameENST00000454757ENST00000388975EGFRchr7

55268106

+SEPT14chr7

55886916

-
In-frameENST00000455089ENST00000388975EGFRchr7

55268106

+SEPT14chr7

55886916

-
In-frameENST00000455089ENST00000388975EGFRchr7

55087058

+SEPT14chr7

55874951

-
In-frameENST00000455089ENST00000388975EGFRchr7

55270318

+SEPT14chr7

55863785

-
intron-3CDSENST00000342916ENST00000388975EGFRchr7

55268106

+SEPT14chr7

55886916

-
intron-3CDSENST00000342916ENST00000388975EGFRchr7

55268106

+SEPT14chr7

55863785

-
intron-3CDSENST00000342916ENST00000388975EGFRchr7

55270318

+SEPT14chr7

55863785

-
intron-3CDSENST00000344576ENST00000388975EGFRchr7

55268106

+SEPT14chr7

55886916

-
intron-3CDSENST00000344576ENST00000388975EGFRchr7

55268106

+SEPT14chr7

55863785

-
intron-3CDSENST00000344576ENST00000388975EGFRchr7

55270318

+SEPT14chr7

55863785

-
intron-3CDSENST00000420316ENST00000388975EGFRchr7

55268106

+SEPT14chr7

55886916

-
intron-3CDSENST00000420316ENST00000388975EGFRchr7

55268106

+SEPT14chr7

55863785

-
intron-3CDSENST00000420316ENST00000388975EGFRchr7

55270318

+SEPT14chr7

55863785

-
intron-3CDSENST00000442591ENST00000388975EGFRchr7

55268106

+SEPT14chr7

55886916

-
intron-3CDSENST00000442591ENST00000388975EGFRchr7

55268106

+SEPT14chr7

55863785

-
intron-3CDSENST00000442591ENST00000388975EGFRchr7

55270318

+SEPT14chr7

55863785

-
intron-3CDSENST00000454757ENST00000388975EGFRchr7

55087058

+SEPT14chr7

55886916

-
intron-3CDSENST00000454757ENST00000388975EGFRchr7

55087058

+SEPT14chr7

55874951

-
intron-3CDSENST00000463948ENST00000388975EGFRchr7

55268106

+SEPT14chr7

55886916

-
intron-3CDSENST00000463948ENST00000388975EGFRchr7

55268106

+SEPT14chr7

55863785

-
intron-3CDSENST00000463948ENST00000388975EGFRchr7

55270318

+SEPT14chr7

55863785

-
intron-intronENST00000342916ENST00000477628EGFRchr7

55268106

+SEPT14chr7

55886916

-
intron-intronENST00000342916ENST00000477628EGFRchr7

55268106

+SEPT14chr7

55863785

-
intron-intronENST00000342916ENST00000477628EGFRchr7

55270318

+SEPT14chr7

55863785

-
intron-intronENST00000344576ENST00000477628EGFRchr7

55268106

+SEPT14chr7

55886916

-
intron-intronENST00000344576ENST00000477628EGFRchr7

55268106

+SEPT14chr7

55863785

-
intron-intronENST00000344576ENST00000477628EGFRchr7

55270318

+SEPT14chr7

55863785

-
intron-intronENST00000420316ENST00000477628EGFRchr7

55268106

+SEPT14chr7

55886916

-
intron-intronENST00000420316ENST00000477628EGFRchr7

55268106

+SEPT14chr7

55863785

-
intron-intronENST00000420316ENST00000477628EGFRchr7

55270318

+SEPT14chr7

55863785

-
intron-intronENST00000442591ENST00000477628EGFRchr7

55268106

+SEPT14chr7

55886916

-
intron-intronENST00000442591ENST00000477628EGFRchr7

55268106

+SEPT14chr7

55863785

-
intron-intronENST00000442591ENST00000477628EGFRchr7

55270318

+SEPT14chr7

55863785

-
intron-intronENST00000454757ENST00000477628EGFRchr7

55087058

+SEPT14chr7

55886916

-
intron-intronENST00000454757ENST00000477628EGFRchr7

55087058

+SEPT14chr7

55874951

-
intron-intronENST00000463948ENST00000477628EGFRchr7

55268106

+SEPT14chr7

55886916

-
intron-intronENST00000463948ENST00000477628EGFRchr7

55268106

+SEPT14chr7

55863785

-
intron-intronENST00000463948ENST00000477628EGFRchr7

55270318

+SEPT14chr7

55863785

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000455089EGFRchr755268106+ENST00000388975SEPT14chr755886916-6016306825736461129
ENST00000275493EGFRchr755268106+ENST00000388975SEPT14chr755886916-6071312317737011174
ENST00000454757EGFRchr755268106+ENST00000388975SEPT14chr755886916-5918297014435481134
ENST00000455089EGFRchr755087058+ENST00000388975SEPT14chr755874951-3196345257826189
ENST00000342916EGFRchr755087058+ENST00000388975SEPT14chr755874951-3185334246815189
ENST00000344576EGFRchr755087058+ENST00000388975SEPT14chr755874951-3184333245814189
ENST00000420316EGFRchr755087058+ENST00000388975SEPT14chr755874951-3183332244813189
ENST00000275493EGFRchr755087058+ENST00000388975SEPT14chr755874951-3116265177746189
ENST00000442591EGFRchr755087058+ENST00000388975SEPT14chr755874951-3099248160729189
ENST00000455089EGFRchr755270318+ENST00000388975SEPT14chr755863785-6284373525734511064

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000455089ENST00000388975EGFRchr755268106+SEPT14chr755886916-0.0001368850.99986315
ENST00000275493ENST00000388975EGFRchr755268106+SEPT14chr755886916-0.0001289610.999871
ENST00000454757ENST00000388975EGFRchr755268106+SEPT14chr755886916-0.0001125340.99988747
ENST00000455089ENST00000388975EGFRchr755087058+SEPT14chr755874951-0.0005325610.99946743
ENST00000342916ENST00000388975EGFRchr755087058+SEPT14chr755874951-0.0005360790.999464
ENST00000344576ENST00000388975EGFRchr755087058+SEPT14chr755874951-0.0005326050.99946743
ENST00000420316ENST00000388975EGFRchr755087058+SEPT14chr755874951-0.0005308350.9994692
ENST00000275493ENST00000388975EGFRchr755087058+SEPT14chr755874951-0.0005167650.9994832
ENST00000442591ENST00000388975EGFRchr755087058+SEPT14chr755874951-0.0005097050.99949026
ENST00000455089ENST00000388975EGFRchr755270318+SEPT14chr755863785-0.0001453270.9998547

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Fusion Genomic Features for EGFR-SEPT14


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for EGFR-SEPT14


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:55268106/chr7:55863785)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
EGFR

P00533

.
FUNCTION: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses (PubMed:2790960, PubMed:10805725, PubMed:27153536). Known ligands include EGF, TGFA/TGF-alpha, AREG, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF (PubMed:2790960, PubMed:7679104, PubMed:8144591, PubMed:9419975, PubMed:15611079, PubMed:12297049, PubMed:27153536, PubMed:20837704, PubMed:17909029). Ligand binding triggers receptor homo- and/or heterodimerization and autophosphorylation on key cytoplasmic residues. The phosphorylated receptor recruits adapter proteins like GRB2 which in turn activates complex downstream signaling cascades. Activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK-ERK, PI3 kinase-AKT, PLCgamma-PKC and STATs modules (PubMed:27153536). May also activate the NF-kappa-B signaling cascade (PubMed:11116146). Also directly phosphorylates other proteins like RGS16, activating its GTPase activity and probably coupling the EGF receptor signaling to the G protein-coupled receptor signaling (PubMed:11602604). Also phosphorylates MUC1 and increases its interaction with SRC and CTNNB1/beta-catenin (PubMed:11483589). Positively regulates cell migration via interaction with CCDC88A/GIV which retains EGFR at the cell membrane following ligand stimulation, promoting EGFR signaling which triggers cell migration (PubMed:20462955). Plays a role in enhancing learning and memory performance (By similarity). {ECO:0000250|UniProtKB:Q01279, ECO:0000269|PubMed:10805725, ECO:0000269|PubMed:11116146, ECO:0000269|PubMed:11483589, ECO:0000269|PubMed:11602604, ECO:0000269|PubMed:12297049, ECO:0000269|PubMed:12297050, ECO:0000269|PubMed:12620237, ECO:0000269|PubMed:12873986, ECO:0000269|PubMed:15374980, ECO:0000269|PubMed:15590694, ECO:0000269|PubMed:15611079, ECO:0000269|PubMed:17115032, ECO:0000269|PubMed:17909029, ECO:0000269|PubMed:19560417, ECO:0000269|PubMed:20462955, ECO:0000269|PubMed:20837704, ECO:0000269|PubMed:21258366, ECO:0000269|PubMed:27153536, ECO:0000269|PubMed:2790960, ECO:0000269|PubMed:7679104, ECO:0000269|PubMed:8144591, ECO:0000269|PubMed:9419975}.; FUNCTION: Isoform 2 may act as an antagonist of EGF action.; FUNCTION: (Microbial infection) Acts as a receptor for hepatitis C virus (HCV) in hepatocytes and facilitates its cell entry. Mediates HCV entry by promoting the formation of the CD81-CLDN1 receptor complexes that are essential for HCV entry and by enhancing membrane fusion of cells expressing HCV envelope glycoproteins. {ECO:0000269|PubMed:21516087}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

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* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEGFRchr7:55268106chr7:55886916ENST00000275493+2428712_9799821211.0DomainProtein kinase
HgeneEGFRchr7:55270318chr7:55863785ENST00000275493+2728712_97910901211.0DomainProtein kinase
HgeneEGFRchr7:55268106chr7:55886916ENST00000275493+2428718_7269821211.0Nucleotide bindingATP
HgeneEGFRchr7:55268106chr7:55886916ENST00000275493+2428790_7919821211.0Nucleotide bindingATP
HgeneEGFRchr7:55270318chr7:55863785ENST00000275493+2728718_72610901211.0Nucleotide bindingATP
HgeneEGFRchr7:55270318chr7:55863785ENST00000275493+2728790_79110901211.0Nucleotide bindingATP
HgeneEGFRchr7:55268106chr7:55886916ENST00000275493+2428688_7049821211.0RegionNote=Important for dimerization%2C phosphorylation and activation
HgeneEGFRchr7:55270318chr7:55863785ENST00000275493+2728688_70410901211.0RegionNote=Important for dimerization%2C phosphorylation and activation
HgeneEGFRchr7:55268106chr7:55886916ENST00000275493+2428390_6009821211.0RepeatNote=Approximate
HgeneEGFRchr7:55268106chr7:55886916ENST00000275493+242875_3009821211.0RepeatNote=Approximate
HgeneEGFRchr7:55270318chr7:55863785ENST00000275493+2728390_60010901211.0RepeatNote=Approximate
HgeneEGFRchr7:55270318chr7:55863785ENST00000275493+272875_30010901211.0RepeatNote=Approximate
HgeneEGFRchr7:55268106chr7:55886916ENST00000275493+242825_6459821211.0Topological domainExtracellular
HgeneEGFRchr7:55270318chr7:55863785ENST00000275493+272825_64510901211.0Topological domainExtracellular
HgeneEGFRchr7:55268106chr7:55886916ENST00000275493+2428646_6689821211.0TransmembraneHelical
HgeneEGFRchr7:55270318chr7:55863785ENST00000275493+2728646_66810901211.0TransmembraneHelical
TgeneSEPT14chr7:55087058chr7:55874951ENST00000388975610332_412272433.0Coiled coilOntology_term=ECO:0000255
TgeneSEPT14chr7:55268106chr7:55886916ENST00000388975510332_412240433.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEGFRchr7:55087058chr7:55874951ENST00000275493+128712_979291211.0DomainProtein kinase
HgeneEGFRchr7:55087058chr7:55874951ENST00000342916+116712_97929629.0DomainProtein kinase
HgeneEGFRchr7:55087058chr7:55874951ENST00000344576+116712_97929706.0DomainProtein kinase
HgeneEGFRchr7:55087058chr7:55874951ENST00000420316+110712_97929406.0DomainProtein kinase
HgeneEGFRchr7:55268106chr7:55886916ENST00000342916+116712_9790629.0DomainProtein kinase
HgeneEGFRchr7:55268106chr7:55886916ENST00000344576+116712_9790706.0DomainProtein kinase
HgeneEGFRchr7:55268106chr7:55886916ENST00000420316+110712_9790406.0DomainProtein kinase
HgeneEGFRchr7:55270318chr7:55863785ENST00000342916+116712_9790629.0DomainProtein kinase
HgeneEGFRchr7:55270318chr7:55863785ENST00000344576+116712_9790706.0DomainProtein kinase
HgeneEGFRchr7:55270318chr7:55863785ENST00000420316+110712_9790406.0DomainProtein kinase
HgeneEGFRchr7:55087058chr7:55874951ENST00000275493+128718_726291211.0Nucleotide bindingATP
HgeneEGFRchr7:55087058chr7:55874951ENST00000275493+128790_791291211.0Nucleotide bindingATP
HgeneEGFRchr7:55087058chr7:55874951ENST00000342916+116718_72629629.0Nucleotide bindingATP
HgeneEGFRchr7:55087058chr7:55874951ENST00000342916+116790_79129629.0Nucleotide bindingATP
HgeneEGFRchr7:55087058chr7:55874951ENST00000344576+116718_72629706.0Nucleotide bindingATP
HgeneEGFRchr7:55087058chr7:55874951ENST00000344576+116790_79129706.0Nucleotide bindingATP
HgeneEGFRchr7:55087058chr7:55874951ENST00000420316+110718_72629406.0Nucleotide bindingATP
HgeneEGFRchr7:55087058chr7:55874951ENST00000420316+110790_79129406.0Nucleotide bindingATP
HgeneEGFRchr7:55268106chr7:55886916ENST00000342916+116718_7260629.0Nucleotide bindingATP
HgeneEGFRchr7:55268106chr7:55886916ENST00000342916+116790_7910629.0Nucleotide bindingATP
HgeneEGFRchr7:55268106chr7:55886916ENST00000344576+116718_7260706.0Nucleotide bindingATP
HgeneEGFRchr7:55268106chr7:55886916ENST00000344576+116790_7910706.0Nucleotide bindingATP
HgeneEGFRchr7:55268106chr7:55886916ENST00000420316+110718_7260406.0Nucleotide bindingATP
HgeneEGFRchr7:55268106chr7:55886916ENST00000420316+110790_7910406.0Nucleotide bindingATP
HgeneEGFRchr7:55270318chr7:55863785ENST00000342916+116718_7260629.0Nucleotide bindingATP
HgeneEGFRchr7:55270318chr7:55863785ENST00000342916+116790_7910629.0Nucleotide bindingATP
HgeneEGFRchr7:55270318chr7:55863785ENST00000344576+116718_7260706.0Nucleotide bindingATP
HgeneEGFRchr7:55270318chr7:55863785ENST00000344576+116790_7910706.0Nucleotide bindingATP
HgeneEGFRchr7:55270318chr7:55863785ENST00000420316+110718_7260406.0Nucleotide bindingATP
HgeneEGFRchr7:55270318chr7:55863785ENST00000420316+110790_7910406.0Nucleotide bindingATP
HgeneEGFRchr7:55087058chr7:55874951ENST00000275493+128688_704291211.0RegionNote=Important for dimerization%2C phosphorylation and activation
HgeneEGFRchr7:55087058chr7:55874951ENST00000342916+116688_70429629.0RegionNote=Important for dimerization%2C phosphorylation and activation
HgeneEGFRchr7:55087058chr7:55874951ENST00000344576+116688_70429706.0RegionNote=Important for dimerization%2C phosphorylation and activation
HgeneEGFRchr7:55087058chr7:55874951ENST00000420316+110688_70429406.0RegionNote=Important for dimerization%2C phosphorylation and activation
HgeneEGFRchr7:55268106chr7:55886916ENST00000342916+116688_7040629.0RegionNote=Important for dimerization%2C phosphorylation and activation
HgeneEGFRchr7:55268106chr7:55886916ENST00000344576+116688_7040706.0RegionNote=Important for dimerization%2C phosphorylation and activation
HgeneEGFRchr7:55268106chr7:55886916ENST00000420316+110688_7040406.0RegionNote=Important for dimerization%2C phosphorylation and activation
HgeneEGFRchr7:55270318chr7:55863785ENST00000342916+116688_7040629.0RegionNote=Important for dimerization%2C phosphorylation and activation
HgeneEGFRchr7:55270318chr7:55863785ENST00000344576+116688_7040706.0RegionNote=Important for dimerization%2C phosphorylation and activation
HgeneEGFRchr7:55270318chr7:55863785ENST00000420316+110688_7040406.0RegionNote=Important for dimerization%2C phosphorylation and activation
HgeneEGFRchr7:55087058chr7:55874951ENST00000275493+128390_600291211.0RepeatNote=Approximate
HgeneEGFRchr7:55087058chr7:55874951ENST00000275493+12875_300291211.0RepeatNote=Approximate
HgeneEGFRchr7:55087058chr7:55874951ENST00000342916+116390_60029629.0RepeatNote=Approximate
HgeneEGFRchr7:55087058chr7:55874951ENST00000342916+11675_30029629.0RepeatNote=Approximate
HgeneEGFRchr7:55087058chr7:55874951ENST00000344576+116390_60029706.0RepeatNote=Approximate
HgeneEGFRchr7:55087058chr7:55874951ENST00000344576+11675_30029706.0RepeatNote=Approximate
HgeneEGFRchr7:55087058chr7:55874951ENST00000420316+110390_60029406.0RepeatNote=Approximate
HgeneEGFRchr7:55087058chr7:55874951ENST00000420316+11075_30029406.0RepeatNote=Approximate
HgeneEGFRchr7:55268106chr7:55886916ENST00000342916+116390_6000629.0RepeatNote=Approximate
HgeneEGFRchr7:55268106chr7:55886916ENST00000342916+11675_3000629.0RepeatNote=Approximate
HgeneEGFRchr7:55268106chr7:55886916ENST00000344576+116390_6000706.0RepeatNote=Approximate
HgeneEGFRchr7:55268106chr7:55886916ENST00000344576+11675_3000706.0RepeatNote=Approximate
HgeneEGFRchr7:55268106chr7:55886916ENST00000420316+110390_6000406.0RepeatNote=Approximate
HgeneEGFRchr7:55268106chr7:55886916ENST00000420316+11075_3000406.0RepeatNote=Approximate
HgeneEGFRchr7:55270318chr7:55863785ENST00000342916+116390_6000629.0RepeatNote=Approximate
HgeneEGFRchr7:55270318chr7:55863785ENST00000342916+11675_3000629.0RepeatNote=Approximate
HgeneEGFRchr7:55270318chr7:55863785ENST00000344576+116390_6000706.0RepeatNote=Approximate
HgeneEGFRchr7:55270318chr7:55863785ENST00000344576+11675_3000706.0RepeatNote=Approximate
HgeneEGFRchr7:55270318chr7:55863785ENST00000420316+110390_6000406.0RepeatNote=Approximate
HgeneEGFRchr7:55270318chr7:55863785ENST00000420316+11075_3000406.0RepeatNote=Approximate
HgeneEGFRchr7:55087058chr7:55874951ENST00000275493+12825_645291211.0Topological domainExtracellular
HgeneEGFRchr7:55087058chr7:55874951ENST00000275493+128669_1210291211.0Topological domainCytoplasmic
HgeneEGFRchr7:55087058chr7:55874951ENST00000342916+11625_64529629.0Topological domainExtracellular
HgeneEGFRchr7:55087058chr7:55874951ENST00000342916+116669_121029629.0Topological domainCytoplasmic
HgeneEGFRchr7:55087058chr7:55874951ENST00000344576+11625_64529706.0Topological domainExtracellular
HgeneEGFRchr7:55087058chr7:55874951ENST00000344576+116669_121029706.0Topological domainCytoplasmic
HgeneEGFRchr7:55087058chr7:55874951ENST00000420316+11025_64529406.0Topological domainExtracellular
HgeneEGFRchr7:55087058chr7:55874951ENST00000420316+110669_121029406.0Topological domainCytoplasmic
HgeneEGFRchr7:55268106chr7:55886916ENST00000275493+2428669_12109821211.0Topological domainCytoplasmic
HgeneEGFRchr7:55268106chr7:55886916ENST00000342916+11625_6450629.0Topological domainExtracellular
HgeneEGFRchr7:55268106chr7:55886916ENST00000342916+116669_12100629.0Topological domainCytoplasmic
HgeneEGFRchr7:55268106chr7:55886916ENST00000344576+11625_6450706.0Topological domainExtracellular
HgeneEGFRchr7:55268106chr7:55886916ENST00000344576+116669_12100706.0Topological domainCytoplasmic
HgeneEGFRchr7:55268106chr7:55886916ENST00000420316+11025_6450406.0Topological domainExtracellular
HgeneEGFRchr7:55268106chr7:55886916ENST00000420316+110669_12100406.0Topological domainCytoplasmic
HgeneEGFRchr7:55270318chr7:55863785ENST00000275493+2728669_121010901211.0Topological domainCytoplasmic
HgeneEGFRchr7:55270318chr7:55863785ENST00000342916+11625_6450629.0Topological domainExtracellular
HgeneEGFRchr7:55270318chr7:55863785ENST00000342916+116669_12100629.0Topological domainCytoplasmic
HgeneEGFRchr7:55270318chr7:55863785ENST00000344576+11625_6450706.0Topological domainExtracellular
HgeneEGFRchr7:55270318chr7:55863785ENST00000344576+116669_12100706.0Topological domainCytoplasmic
HgeneEGFRchr7:55270318chr7:55863785ENST00000420316+11025_6450406.0Topological domainExtracellular
HgeneEGFRchr7:55270318chr7:55863785ENST00000420316+110669_12100406.0Topological domainCytoplasmic
HgeneEGFRchr7:55087058chr7:55874951ENST00000275493+128646_668291211.0TransmembraneHelical
HgeneEGFRchr7:55087058chr7:55874951ENST00000342916+116646_66829629.0TransmembraneHelical
HgeneEGFRchr7:55087058chr7:55874951ENST00000344576+116646_66829706.0TransmembraneHelical
HgeneEGFRchr7:55087058chr7:55874951ENST00000420316+110646_66829406.0TransmembraneHelical
HgeneEGFRchr7:55268106chr7:55886916ENST00000342916+116646_6680629.0TransmembraneHelical
HgeneEGFRchr7:55268106chr7:55886916ENST00000344576+116646_6680706.0TransmembraneHelical
HgeneEGFRchr7:55268106chr7:55886916ENST00000420316+110646_6680406.0TransmembraneHelical
HgeneEGFRchr7:55270318chr7:55863785ENST00000342916+116646_6680629.0TransmembraneHelical
HgeneEGFRchr7:55270318chr7:55863785ENST00000344576+116646_6680706.0TransmembraneHelical
HgeneEGFRchr7:55270318chr7:55863785ENST00000420316+110646_6680406.0TransmembraneHelical
TgeneSEPT14chr7:55270318chr7:55863785ENST00000388975810332_412373433.0Coiled coilOntology_term=ECO:0000255
TgeneSEPT14chr7:55087058chr7:55874951ENST0000038897561049_315272433.0DomainSeptin-type G
TgeneSEPT14chr7:55268106chr7:55886916ENST0000038897551049_315240433.0DomainSeptin-type G
TgeneSEPT14chr7:55270318chr7:55863785ENST0000038897581049_315373433.0DomainSeptin-type G
TgeneSEPT14chr7:55087058chr7:55874951ENST00000388975610195_203272433.0Nucleotide bindingGTP
TgeneSEPT14chr7:55268106chr7:55886916ENST00000388975510195_203240433.0Nucleotide bindingGTP
TgeneSEPT14chr7:55270318chr7:55863785ENST00000388975810195_203373433.0Nucleotide bindingGTP
TgeneSEPT14chr7:55087058chr7:55874951ENST00000388975610111_114272433.0RegionG3 motif
TgeneSEPT14chr7:55087058chr7:55874951ENST00000388975610194_197272433.0RegionG4 motif
TgeneSEPT14chr7:55087058chr7:55874951ENST0000038897561059_66272433.0RegionG1 motif
TgeneSEPT14chr7:55268106chr7:55886916ENST00000388975510111_114240433.0RegionG3 motif
TgeneSEPT14chr7:55268106chr7:55886916ENST00000388975510194_197240433.0RegionG4 motif
TgeneSEPT14chr7:55268106chr7:55886916ENST0000038897551059_66240433.0RegionG1 motif
TgeneSEPT14chr7:55270318chr7:55863785ENST00000388975810111_114373433.0RegionG3 motif
TgeneSEPT14chr7:55270318chr7:55863785ENST00000388975810194_197373433.0RegionG4 motif
TgeneSEPT14chr7:55270318chr7:55863785ENST0000038897581059_66373433.0RegionG1 motif


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Fusion Gene Sequence for EGFR-SEPT14


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>25482_25482_1_EGFR-SEPT14_EGFR_chr7_55087058_ENST00000275493_SEPT14_chr7_55874951_ENST00000388975_length(transcript)=3116nt_BP=265nt
GCCGGAGTCCCGAGCTAGCCCCGGCGGCCGCCGCCGCCCAGACCGGACGACAGGCCACCTCGTCGGCGTCCGCCCGAGTCCCCGCCTCGC
CGCCAACGCCACAACCACCGCGCACGGCCCCCTGACTCCGTCCAGTATTGATCGGGAGAGCCGGAGCGAGCTCTTCGGGGAGCAGCGATG
CGACCCTCCGGGACGGCCGGGGCAGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGTGGAA
AATGAAAATCACTGTGACTTCGTTAAGCTCCGAGATATGCTTCTTTGTACCAATATGGAAAATCTAAAAGAAAAAACCCACACTCAGCAC
TATGAATGTTATAGGTACCAAAAACTGCAGAAAATGGGCTTTACAGATGTGGGTCCAAACAACCAGCCAGTTAGTTTTCAAGAAATCTTT
GAAGCCAAAAGACAAGAGTTCTATGATCAATGTCAGAGGGAAGAAGAAGAGTTGAAACAGAGATTTATGCAGCGAGTCAAGGAGAAAGAA
GCAACATTTAAAGAAGCTGAAAAAGAGCTGCAGGACAAGTTCGAGCATCTTAAAATGATTCAACAGGAGGAGATAAGGAAGCTCGAGGAA
GAGAAAAAACAACTGGAAGGAGAAATCATAGATTTTTATAAAATGAAAGCTGCCTCCGAAGCACTGCAGACTCAGCTGAGCACCGATACA
AAGAAAGACAAACATCGTAAGAAATAATAGTTTCTCTTACTATTCTGAGAGCCCTATCATTCTACATCGCAACTTCCTGTGAGATTGTCT
TTGTAGCATTTAACTCTGAAGTTCTCATTTTAAAAATTGGCTTGCTTATTGTATATTTTCCCCAACTAAAGTGTGAACTCCTAGCGGGGT
GTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGACCACCTGAGGTCAGGAGTTCAAAACCAGCCTGACCAAA
ATGATGAAACCCTGCCTCTACTAAAAATACAAAAATTAGCTGGGTTTGGTGGCCGGTACCTGTAATCCCAGCCACTTGGGAGGCTGAGGC
AGGAGAATCACTTGAACCCCGGAGGTGGAGGTTGCAGTGAGCCAAGATCTCACCATTGTACTCCAGCCTGGGTGACAAGAGCAAAACTCC
GCCTCAAAAAAAAAAAAAAAAAAAAAAGTATGAACTCCCAGAAGGCAGATCCTGTGTCCCTCTTTTCAGATTCTGTATCTTGGCACTTAG
GACGTACACTAACACAAATATGACTTTCAATCAATATTTGCCAAAATGAAAAAACAAAAGAAACACGTAGCATCATGTAAAAGGAGCTGG
TTAGGTGGAGAAATTTATTTACCATAGTCCTGCTTTTGGATCCAGTAGTGACTTTTAACTTTTATATCCAAATAGAAGCTGGAGGCTTTG
TTGGGGACTCATAGGCATAAAATGTTAAGTTATACAAATCTAATTAATAGGCCTATTTTCCTTTTTAAGTTCTACTACTGATAATTTCTT
GACAGTTTTTATGATAAAAGGTTGGAATTTGATAAGAACTCCCATGCTTTTGTGTCAGACTTAAAACTGATATTAGAATAAAGAATTCAA
AAGCTAGAGAAAGAGTTGCATTTGAATGATAATATTATGTGTTACAGATTTGGGGTATATGCCAAAGTTATCAAAGTTGTAGAAAATAAG
GCCAGGTGTGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGCGGTCAGGAGCTTGAGAACAGCCC
GGCCAACATGACGAAACCCCATCTCTACTAATAATACAAAAGTTAGCCGGGTGTGGTGTTGTGCACCTGTAGTCCCTGCTACTCGGAAAG
CTGAGGCAGGAGAATCGCTTGTAGCCAGGAGGCAGAGGTTGTAGTGAGCAGAGATTGCGCCACTGCACTCCAGCCTGGGTGACAGAGCGC
TGAGTCACCACACCTGGTATAAGCCACTGTGCCTGACCCACAATGACTTTTATACATATTGTTAAATCATCTTACAGATTTTATAATTTG
GGGGAAGAAAAATTTTACTAAATGATCTTTTAATGGAAACTCTACAAGAACCAGAATCTTTGCTTTGTTCACTTATGTATCCATTCCTAG
GCCTAGAAAAATGTCTGACGCATAGCAGCAATTATTCATTGAATAAATGGACCCAGCAATAGTACATTAGCTATGCCATATGCATACATT
AAAAATGTAGATTATTGACTTTCAAAAGATAATTAATGTAACTTCTTACTGCTTCTGAACATGTTTGTGAGTTATATTGCTGAGGGACCT
TTATCTTCTCATTCTTTCATCTTAATCCAATGTTATTAAAACTGAAACTGAAATCACCAATATTATTCCATATTTAAAAATAACATCTAC
CTTATAAAAATTATCATTGTGCTGCATTTGAGAATAGACTTTTTAGGTAATAATGGTATAATCCATAGGGTTTTTGAGGGCACAGAAGGA
TTCATGCTAACAGAACATTTTATTTTCTATTTTCCAAGAGCTATAAAACATGATATTATATGATACTATAAGGCATATTTTTATTTTCCA
TAATTTTTTCTAAAAAAAATTAGTGTTGGTTTTCCATATAACTTTTAACTTTATAAGTAAATATTTGTCTCTTTCAGCTCCAGTTTCATG
TGAAATAGAGTTTCCAGATTTATGTAGCATGGAAAGTTTTAATACGTCAGTTACTGATTTTTGCCAGTCATTTTCTCAATTATTTACTTC
TTTTATCTTTAGTTGATTTTTTTTGTAGTGACAAGTTTTGTTTCTATTCTCATTTCCTTTTGTGTATATTCTATGTAGATTTCGTTTTTG
GTTACTATGAAAATTACATATAACATCCTGGAGTTATAACATTCTGATTTGAATTTATTTCAACTTAACTTCAATCACATACCAAAATTC
TACTGCTATATAGGTCTACTCTTTTTAGGTTATTGATGTAACAAATTGTATCTTTATTCATTGTACACCACCTAACAGATTTATAATTAC

>25482_25482_1_EGFR-SEPT14_EGFR_chr7_55087058_ENST00000275493_SEPT14_chr7_55874951_ENST00000388975_length(amino acids)=189AA_BP=29
MRPSGTAGAALLALLAALCPASRALEEKKVENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSFQEI
FEAKRQEFYDQCQREEEELKQRFMQRVKEKEATFKEAEKELQDKFEHLKMIQQEEIRKLEEEKKQLEGEIIDFYKMKAASEALQTQLSTD

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>25482_25482_2_EGFR-SEPT14_EGFR_chr7_55087058_ENST00000342916_SEPT14_chr7_55874951_ENST00000388975_length(transcript)=3185nt_BP=334nt
CCCCGGCGCAGCGCGGCCGCAGCAGCCTCCGCCCCCCGCACGGTGTGAGCGCCCGACGCGGCCGAGGCGGCCGGAGTCCCGAGCTAGCCC
CGGCGGCCGCCGCCGCCCAGACCGGACGACAGGCCACCTCGTCGGCGTCCGCCCGAGTCCCCGCCTCGCCGCCAACGCCACAACCACCGC
GCACGGCCCCCTGACTCCGTCCAGTATTGATCGGGAGAGCCGGAGCGAGCTCTTCGGGGAGCAGCGATGCGACCCTCCGGGACGGCCGGG
GCAGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGTGGAAAATGAAAATCACTGTGACTTC
GTTAAGCTCCGAGATATGCTTCTTTGTACCAATATGGAAAATCTAAAAGAAAAAACCCACACTCAGCACTATGAATGTTATAGGTACCAA
AAACTGCAGAAAATGGGCTTTACAGATGTGGGTCCAAACAACCAGCCAGTTAGTTTTCAAGAAATCTTTGAAGCCAAAAGACAAGAGTTC
TATGATCAATGTCAGAGGGAAGAAGAAGAGTTGAAACAGAGATTTATGCAGCGAGTCAAGGAGAAAGAAGCAACATTTAAAGAAGCTGAA
AAAGAGCTGCAGGACAAGTTCGAGCATCTTAAAATGATTCAACAGGAGGAGATAAGGAAGCTCGAGGAAGAGAAAAAACAACTGGAAGGA
GAAATCATAGATTTTTATAAAATGAAAGCTGCCTCCGAAGCACTGCAGACTCAGCTGAGCACCGATACAAAGAAAGACAAACATCGTAAG
AAATAATAGTTTCTCTTACTATTCTGAGAGCCCTATCATTCTACATCGCAACTTCCTGTGAGATTGTCTTTGTAGCATTTAACTCTGAAG
TTCTCATTTTAAAAATTGGCTTGCTTATTGTATATTTTCCCCAACTAAAGTGTGAACTCCTAGCGGGGTGTGGTGGCTCATGCCTGTAAT
CCCAGCACTTTGGGAGGCTGAGGCGGGTGGACCACCTGAGGTCAGGAGTTCAAAACCAGCCTGACCAAAATGATGAAACCCTGCCTCTAC
TAAAAATACAAAAATTAGCTGGGTTTGGTGGCCGGTACCTGTAATCCCAGCCACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCCG
GAGGTGGAGGTTGCAGTGAGCCAAGATCTCACCATTGTACTCCAGCCTGGGTGACAAGAGCAAAACTCCGCCTCAAAAAAAAAAAAAAAA
AAAAAAGTATGAACTCCCAGAAGGCAGATCCTGTGTCCCTCTTTTCAGATTCTGTATCTTGGCACTTAGGACGTACACTAACACAAATAT
GACTTTCAATCAATATTTGCCAAAATGAAAAAACAAAAGAAACACGTAGCATCATGTAAAAGGAGCTGGTTAGGTGGAGAAATTTATTTA
CCATAGTCCTGCTTTTGGATCCAGTAGTGACTTTTAACTTTTATATCCAAATAGAAGCTGGAGGCTTTGTTGGGGACTCATAGGCATAAA
ATGTTAAGTTATACAAATCTAATTAATAGGCCTATTTTCCTTTTTAAGTTCTACTACTGATAATTTCTTGACAGTTTTTATGATAAAAGG
TTGGAATTTGATAAGAACTCCCATGCTTTTGTGTCAGACTTAAAACTGATATTAGAATAAAGAATTCAAAAGCTAGAGAAAGAGTTGCAT
TTGAATGATAATATTATGTGTTACAGATTTGGGGTATATGCCAAAGTTATCAAAGTTGTAGAAAATAAGGCCAGGTGTGGTGGCTCACAC
CTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGCGGTCAGGAGCTTGAGAACAGCCCGGCCAACATGACGAAACCCCA
TCTCTACTAATAATACAAAAGTTAGCCGGGTGTGGTGTTGTGCACCTGTAGTCCCTGCTACTCGGAAAGCTGAGGCAGGAGAATCGCTTG
TAGCCAGGAGGCAGAGGTTGTAGTGAGCAGAGATTGCGCCACTGCACTCCAGCCTGGGTGACAGAGCGCTGAGTCACCACACCTGGTATA
AGCCACTGTGCCTGACCCACAATGACTTTTATACATATTGTTAAATCATCTTACAGATTTTATAATTTGGGGGAAGAAAAATTTTACTAA
ATGATCTTTTAATGGAAACTCTACAAGAACCAGAATCTTTGCTTTGTTCACTTATGTATCCATTCCTAGGCCTAGAAAAATGTCTGACGC
ATAGCAGCAATTATTCATTGAATAAATGGACCCAGCAATAGTACATTAGCTATGCCATATGCATACATTAAAAATGTAGATTATTGACTT
TCAAAAGATAATTAATGTAACTTCTTACTGCTTCTGAACATGTTTGTGAGTTATATTGCTGAGGGACCTTTATCTTCTCATTCTTTCATC
TTAATCCAATGTTATTAAAACTGAAACTGAAATCACCAATATTATTCCATATTTAAAAATAACATCTACCTTATAAAAATTATCATTGTG
CTGCATTTGAGAATAGACTTTTTAGGTAATAATGGTATAATCCATAGGGTTTTTGAGGGCACAGAAGGATTCATGCTAACAGAACATTTT
ATTTTCTATTTTCCAAGAGCTATAAAACATGATATTATATGATACTATAAGGCATATTTTTATTTTCCATAATTTTTTCTAAAAAAAATT
AGTGTTGGTTTTCCATATAACTTTTAACTTTATAAGTAAATATTTGTCTCTTTCAGCTCCAGTTTCATGTGAAATAGAGTTTCCAGATTT
ATGTAGCATGGAAAGTTTTAATACGTCAGTTACTGATTTTTGCCAGTCATTTTCTCAATTATTTACTTCTTTTATCTTTAGTTGATTTTT
TTTGTAGTGACAAGTTTTGTTTCTATTCTCATTTCCTTTTGTGTATATTCTATGTAGATTTCGTTTTTGGTTACTATGAAAATTACATAT
AACATCCTGGAGTTATAACATTCTGATTTGAATTTATTTCAACTTAACTTCAATCACATACCAAAATTCTACTGCTATATAGGTCTACTC
TTTTTAGGTTATTGATGTAACAAATTGTATCTTTATTCATTGTACACCACCTAACAGATTTATAATTACATTTTATGCATTTGTCTTTTA

>25482_25482_2_EGFR-SEPT14_EGFR_chr7_55087058_ENST00000342916_SEPT14_chr7_55874951_ENST00000388975_length(amino acids)=189AA_BP=29
MRPSGTAGAALLALLAALCPASRALEEKKVENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSFQEI
FEAKRQEFYDQCQREEEELKQRFMQRVKEKEATFKEAEKELQDKFEHLKMIQQEEIRKLEEEKKQLEGEIIDFYKMKAASEALQTQLSTD

--------------------------------------------------------------
>25482_25482_3_EGFR-SEPT14_EGFR_chr7_55087058_ENST00000344576_SEPT14_chr7_55874951_ENST00000388975_length(transcript)=3184nt_BP=333nt
CCCGGCGCAGCGCGGCCGCAGCAGCCTCCGCCCCCCGCACGGTGTGAGCGCCCGACGCGGCCGAGGCGGCCGGAGTCCCGAGCTAGCCCC
GGCGGCCGCCGCCGCCCAGACCGGACGACAGGCCACCTCGTCGGCGTCCGCCCGAGTCCCCGCCTCGCCGCCAACGCCACAACCACCGCG
CACGGCCCCCTGACTCCGTCCAGTATTGATCGGGAGAGCCGGAGCGAGCTCTTCGGGGAGCAGCGATGCGACCCTCCGGGACGGCCGGGG
CAGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGTGGAAAATGAAAATCACTGTGACTTCG
TTAAGCTCCGAGATATGCTTCTTTGTACCAATATGGAAAATCTAAAAGAAAAAACCCACACTCAGCACTATGAATGTTATAGGTACCAAA
AACTGCAGAAAATGGGCTTTACAGATGTGGGTCCAAACAACCAGCCAGTTAGTTTTCAAGAAATCTTTGAAGCCAAAAGACAAGAGTTCT
ATGATCAATGTCAGAGGGAAGAAGAAGAGTTGAAACAGAGATTTATGCAGCGAGTCAAGGAGAAAGAAGCAACATTTAAAGAAGCTGAAA
AAGAGCTGCAGGACAAGTTCGAGCATCTTAAAATGATTCAACAGGAGGAGATAAGGAAGCTCGAGGAAGAGAAAAAACAACTGGAAGGAG
AAATCATAGATTTTTATAAAATGAAAGCTGCCTCCGAAGCACTGCAGACTCAGCTGAGCACCGATACAAAGAAAGACAAACATCGTAAGA
AATAATAGTTTCTCTTACTATTCTGAGAGCCCTATCATTCTACATCGCAACTTCCTGTGAGATTGTCTTTGTAGCATTTAACTCTGAAGT
TCTCATTTTAAAAATTGGCTTGCTTATTGTATATTTTCCCCAACTAAAGTGTGAACTCCTAGCGGGGTGTGGTGGCTCATGCCTGTAATC
CCAGCACTTTGGGAGGCTGAGGCGGGTGGACCACCTGAGGTCAGGAGTTCAAAACCAGCCTGACCAAAATGATGAAACCCTGCCTCTACT
AAAAATACAAAAATTAGCTGGGTTTGGTGGCCGGTACCTGTAATCCCAGCCACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCCGG
AGGTGGAGGTTGCAGTGAGCCAAGATCTCACCATTGTACTCCAGCCTGGGTGACAAGAGCAAAACTCCGCCTCAAAAAAAAAAAAAAAAA
AAAAAGTATGAACTCCCAGAAGGCAGATCCTGTGTCCCTCTTTTCAGATTCTGTATCTTGGCACTTAGGACGTACACTAACACAAATATG
ACTTTCAATCAATATTTGCCAAAATGAAAAAACAAAAGAAACACGTAGCATCATGTAAAAGGAGCTGGTTAGGTGGAGAAATTTATTTAC
CATAGTCCTGCTTTTGGATCCAGTAGTGACTTTTAACTTTTATATCCAAATAGAAGCTGGAGGCTTTGTTGGGGACTCATAGGCATAAAA
TGTTAAGTTATACAAATCTAATTAATAGGCCTATTTTCCTTTTTAAGTTCTACTACTGATAATTTCTTGACAGTTTTTATGATAAAAGGT
TGGAATTTGATAAGAACTCCCATGCTTTTGTGTCAGACTTAAAACTGATATTAGAATAAAGAATTCAAAAGCTAGAGAAAGAGTTGCATT
TGAATGATAATATTATGTGTTACAGATTTGGGGTATATGCCAAAGTTATCAAAGTTGTAGAAAATAAGGCCAGGTGTGGTGGCTCACACC
TGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGCGGTCAGGAGCTTGAGAACAGCCCGGCCAACATGACGAAACCCCAT
CTCTACTAATAATACAAAAGTTAGCCGGGTGTGGTGTTGTGCACCTGTAGTCCCTGCTACTCGGAAAGCTGAGGCAGGAGAATCGCTTGT
AGCCAGGAGGCAGAGGTTGTAGTGAGCAGAGATTGCGCCACTGCACTCCAGCCTGGGTGACAGAGCGCTGAGTCACCACACCTGGTATAA
GCCACTGTGCCTGACCCACAATGACTTTTATACATATTGTTAAATCATCTTACAGATTTTATAATTTGGGGGAAGAAAAATTTTACTAAA
TGATCTTTTAATGGAAACTCTACAAGAACCAGAATCTTTGCTTTGTTCACTTATGTATCCATTCCTAGGCCTAGAAAAATGTCTGACGCA
TAGCAGCAATTATTCATTGAATAAATGGACCCAGCAATAGTACATTAGCTATGCCATATGCATACATTAAAAATGTAGATTATTGACTTT
CAAAAGATAATTAATGTAACTTCTTACTGCTTCTGAACATGTTTGTGAGTTATATTGCTGAGGGACCTTTATCTTCTCATTCTTTCATCT
TAATCCAATGTTATTAAAACTGAAACTGAAATCACCAATATTATTCCATATTTAAAAATAACATCTACCTTATAAAAATTATCATTGTGC
TGCATTTGAGAATAGACTTTTTAGGTAATAATGGTATAATCCATAGGGTTTTTGAGGGCACAGAAGGATTCATGCTAACAGAACATTTTA
TTTTCTATTTTCCAAGAGCTATAAAACATGATATTATATGATACTATAAGGCATATTTTTATTTTCCATAATTTTTTCTAAAAAAAATTA
GTGTTGGTTTTCCATATAACTTTTAACTTTATAAGTAAATATTTGTCTCTTTCAGCTCCAGTTTCATGTGAAATAGAGTTTCCAGATTTA
TGTAGCATGGAAAGTTTTAATACGTCAGTTACTGATTTTTGCCAGTCATTTTCTCAATTATTTACTTCTTTTATCTTTAGTTGATTTTTT
TTGTAGTGACAAGTTTTGTTTCTATTCTCATTTCCTTTTGTGTATATTCTATGTAGATTTCGTTTTTGGTTACTATGAAAATTACATATA
ACATCCTGGAGTTATAACATTCTGATTTGAATTTATTTCAACTTAACTTCAATCACATACCAAAATTCTACTGCTATATAGGTCTACTCT
TTTTAGGTTATTGATGTAACAAATTGTATCTTTATTCATTGTACACCACCTAACAGATTTATAATTACATTTTATGCATTTGTCTTTTAA

>25482_25482_3_EGFR-SEPT14_EGFR_chr7_55087058_ENST00000344576_SEPT14_chr7_55874951_ENST00000388975_length(amino acids)=189AA_BP=29
MRPSGTAGAALLALLAALCPASRALEEKKVENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSFQEI
FEAKRQEFYDQCQREEEELKQRFMQRVKEKEATFKEAEKELQDKFEHLKMIQQEEIRKLEEEKKQLEGEIIDFYKMKAASEALQTQLSTD

--------------------------------------------------------------
>25482_25482_4_EGFR-SEPT14_EGFR_chr7_55087058_ENST00000420316_SEPT14_chr7_55874951_ENST00000388975_length(transcript)=3183nt_BP=332nt
CCGGCGCAGCGCGGCCGCAGCAGCCTCCGCCCCCCGCACGGTGTGAGCGCCCGACGCGGCCGAGGCGGCCGGAGTCCCGAGCTAGCCCCG
GCGGCCGCCGCCGCCCAGACCGGACGACAGGCCACCTCGTCGGCGTCCGCCCGAGTCCCCGCCTCGCCGCCAACGCCACAACCACCGCGC
ACGGCCCCCTGACTCCGTCCAGTATTGATCGGGAGAGCCGGAGCGAGCTCTTCGGGGAGCAGCGATGCGACCCTCCGGGACGGCCGGGGC
AGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGTGGAAAATGAAAATCACTGTGACTTCGT
TAAGCTCCGAGATATGCTTCTTTGTACCAATATGGAAAATCTAAAAGAAAAAACCCACACTCAGCACTATGAATGTTATAGGTACCAAAA
ACTGCAGAAAATGGGCTTTACAGATGTGGGTCCAAACAACCAGCCAGTTAGTTTTCAAGAAATCTTTGAAGCCAAAAGACAAGAGTTCTA
TGATCAATGTCAGAGGGAAGAAGAAGAGTTGAAACAGAGATTTATGCAGCGAGTCAAGGAGAAAGAAGCAACATTTAAAGAAGCTGAAAA
AGAGCTGCAGGACAAGTTCGAGCATCTTAAAATGATTCAACAGGAGGAGATAAGGAAGCTCGAGGAAGAGAAAAAACAACTGGAAGGAGA
AATCATAGATTTTTATAAAATGAAAGCTGCCTCCGAAGCACTGCAGACTCAGCTGAGCACCGATACAAAGAAAGACAAACATCGTAAGAA
ATAATAGTTTCTCTTACTATTCTGAGAGCCCTATCATTCTACATCGCAACTTCCTGTGAGATTGTCTTTGTAGCATTTAACTCTGAAGTT
CTCATTTTAAAAATTGGCTTGCTTATTGTATATTTTCCCCAACTAAAGTGTGAACTCCTAGCGGGGTGTGGTGGCTCATGCCTGTAATCC
CAGCACTTTGGGAGGCTGAGGCGGGTGGACCACCTGAGGTCAGGAGTTCAAAACCAGCCTGACCAAAATGATGAAACCCTGCCTCTACTA
AAAATACAAAAATTAGCTGGGTTTGGTGGCCGGTACCTGTAATCCCAGCCACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCCGGA
GGTGGAGGTTGCAGTGAGCCAAGATCTCACCATTGTACTCCAGCCTGGGTGACAAGAGCAAAACTCCGCCTCAAAAAAAAAAAAAAAAAA
AAAAGTATGAACTCCCAGAAGGCAGATCCTGTGTCCCTCTTTTCAGATTCTGTATCTTGGCACTTAGGACGTACACTAACACAAATATGA
CTTTCAATCAATATTTGCCAAAATGAAAAAACAAAAGAAACACGTAGCATCATGTAAAAGGAGCTGGTTAGGTGGAGAAATTTATTTACC
ATAGTCCTGCTTTTGGATCCAGTAGTGACTTTTAACTTTTATATCCAAATAGAAGCTGGAGGCTTTGTTGGGGACTCATAGGCATAAAAT
GTTAAGTTATACAAATCTAATTAATAGGCCTATTTTCCTTTTTAAGTTCTACTACTGATAATTTCTTGACAGTTTTTATGATAAAAGGTT
GGAATTTGATAAGAACTCCCATGCTTTTGTGTCAGACTTAAAACTGATATTAGAATAAAGAATTCAAAAGCTAGAGAAAGAGTTGCATTT
GAATGATAATATTATGTGTTACAGATTTGGGGTATATGCCAAAGTTATCAAAGTTGTAGAAAATAAGGCCAGGTGTGGTGGCTCACACCT
GTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGCGGTCAGGAGCTTGAGAACAGCCCGGCCAACATGACGAAACCCCATC
TCTACTAATAATACAAAAGTTAGCCGGGTGTGGTGTTGTGCACCTGTAGTCCCTGCTACTCGGAAAGCTGAGGCAGGAGAATCGCTTGTA
GCCAGGAGGCAGAGGTTGTAGTGAGCAGAGATTGCGCCACTGCACTCCAGCCTGGGTGACAGAGCGCTGAGTCACCACACCTGGTATAAG
CCACTGTGCCTGACCCACAATGACTTTTATACATATTGTTAAATCATCTTACAGATTTTATAATTTGGGGGAAGAAAAATTTTACTAAAT
GATCTTTTAATGGAAACTCTACAAGAACCAGAATCTTTGCTTTGTTCACTTATGTATCCATTCCTAGGCCTAGAAAAATGTCTGACGCAT
AGCAGCAATTATTCATTGAATAAATGGACCCAGCAATAGTACATTAGCTATGCCATATGCATACATTAAAAATGTAGATTATTGACTTTC
AAAAGATAATTAATGTAACTTCTTACTGCTTCTGAACATGTTTGTGAGTTATATTGCTGAGGGACCTTTATCTTCTCATTCTTTCATCTT
AATCCAATGTTATTAAAACTGAAACTGAAATCACCAATATTATTCCATATTTAAAAATAACATCTACCTTATAAAAATTATCATTGTGCT
GCATTTGAGAATAGACTTTTTAGGTAATAATGGTATAATCCATAGGGTTTTTGAGGGCACAGAAGGATTCATGCTAACAGAACATTTTAT
TTTCTATTTTCCAAGAGCTATAAAACATGATATTATATGATACTATAAGGCATATTTTTATTTTCCATAATTTTTTCTAAAAAAAATTAG
TGTTGGTTTTCCATATAACTTTTAACTTTATAAGTAAATATTTGTCTCTTTCAGCTCCAGTTTCATGTGAAATAGAGTTTCCAGATTTAT
GTAGCATGGAAAGTTTTAATACGTCAGTTACTGATTTTTGCCAGTCATTTTCTCAATTATTTACTTCTTTTATCTTTAGTTGATTTTTTT
TGTAGTGACAAGTTTTGTTTCTATTCTCATTTCCTTTTGTGTATATTCTATGTAGATTTCGTTTTTGGTTACTATGAAAATTACATATAA
CATCCTGGAGTTATAACATTCTGATTTGAATTTATTTCAACTTAACTTCAATCACATACCAAAATTCTACTGCTATATAGGTCTACTCTT
TTTAGGTTATTGATGTAACAAATTGTATCTTTATTCATTGTACACCACCTAACAGATTTATAATTACATTTTATGCATTTGTCTTTTAAA

>25482_25482_4_EGFR-SEPT14_EGFR_chr7_55087058_ENST00000420316_SEPT14_chr7_55874951_ENST00000388975_length(amino acids)=189AA_BP=29
MRPSGTAGAALLALLAALCPASRALEEKKVENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSFQEI
FEAKRQEFYDQCQREEEELKQRFMQRVKEKEATFKEAEKELQDKFEHLKMIQQEEIRKLEEEKKQLEGEIIDFYKMKAASEALQTQLSTD

--------------------------------------------------------------
>25482_25482_5_EGFR-SEPT14_EGFR_chr7_55087058_ENST00000442591_SEPT14_chr7_55874951_ENST00000388975_length(transcript)=3099nt_BP=248nt
GCCCCGGCGGCCGCCGCCGCCCAGACCGGACGACAGGCCACCTCGTCGGCGTCCGCCCGAGTCCCCGCCTCGCCGCCAACGCCACAACCA
CCGCGCACGGCCCCCTGACTCCGTCCAGTATTGATCGGGAGAGCCGGAGCGAGCTCTTCGGGGAGCAGCGATGCGACCCTCCGGGACGGC
CGGGGCAGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGTGGAAAATGAAAATCACTGTGA
CTTCGTTAAGCTCCGAGATATGCTTCTTTGTACCAATATGGAAAATCTAAAAGAAAAAACCCACACTCAGCACTATGAATGTTATAGGTA
CCAAAAACTGCAGAAAATGGGCTTTACAGATGTGGGTCCAAACAACCAGCCAGTTAGTTTTCAAGAAATCTTTGAAGCCAAAAGACAAGA
GTTCTATGATCAATGTCAGAGGGAAGAAGAAGAGTTGAAACAGAGATTTATGCAGCGAGTCAAGGAGAAAGAAGCAACATTTAAAGAAGC
TGAAAAAGAGCTGCAGGACAAGTTCGAGCATCTTAAAATGATTCAACAGGAGGAGATAAGGAAGCTCGAGGAAGAGAAAAAACAACTGGA
AGGAGAAATCATAGATTTTTATAAAATGAAAGCTGCCTCCGAAGCACTGCAGACTCAGCTGAGCACCGATACAAAGAAAGACAAACATCG
TAAGAAATAATAGTTTCTCTTACTATTCTGAGAGCCCTATCATTCTACATCGCAACTTCCTGTGAGATTGTCTTTGTAGCATTTAACTCT
GAAGTTCTCATTTTAAAAATTGGCTTGCTTATTGTATATTTTCCCCAACTAAAGTGTGAACTCCTAGCGGGGTGTGGTGGCTCATGCCTG
TAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGACCACCTGAGGTCAGGAGTTCAAAACCAGCCTGACCAAAATGATGAAACCCTGCCT
CTACTAAAAATACAAAAATTAGCTGGGTTTGGTGGCCGGTACCTGTAATCCCAGCCACTTGGGAGGCTGAGGCAGGAGAATCACTTGAAC
CCCGGAGGTGGAGGTTGCAGTGAGCCAAGATCTCACCATTGTACTCCAGCCTGGGTGACAAGAGCAAAACTCCGCCTCAAAAAAAAAAAA
AAAAAAAAAAGTATGAACTCCCAGAAGGCAGATCCTGTGTCCCTCTTTTCAGATTCTGTATCTTGGCACTTAGGACGTACACTAACACAA
ATATGACTTTCAATCAATATTTGCCAAAATGAAAAAACAAAAGAAACACGTAGCATCATGTAAAAGGAGCTGGTTAGGTGGAGAAATTTA
TTTACCATAGTCCTGCTTTTGGATCCAGTAGTGACTTTTAACTTTTATATCCAAATAGAAGCTGGAGGCTTTGTTGGGGACTCATAGGCA
TAAAATGTTAAGTTATACAAATCTAATTAATAGGCCTATTTTCCTTTTTAAGTTCTACTACTGATAATTTCTTGACAGTTTTTATGATAA
AAGGTTGGAATTTGATAAGAACTCCCATGCTTTTGTGTCAGACTTAAAACTGATATTAGAATAAAGAATTCAAAAGCTAGAGAAAGAGTT
GCATTTGAATGATAATATTATGTGTTACAGATTTGGGGTATATGCCAAAGTTATCAAAGTTGTAGAAAATAAGGCCAGGTGTGGTGGCTC
ACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGCGGTCAGGAGCTTGAGAACAGCCCGGCCAACATGACGAAAC
CCCATCTCTACTAATAATACAAAAGTTAGCCGGGTGTGGTGTTGTGCACCTGTAGTCCCTGCTACTCGGAAAGCTGAGGCAGGAGAATCG
CTTGTAGCCAGGAGGCAGAGGTTGTAGTGAGCAGAGATTGCGCCACTGCACTCCAGCCTGGGTGACAGAGCGCTGAGTCACCACACCTGG
TATAAGCCACTGTGCCTGACCCACAATGACTTTTATACATATTGTTAAATCATCTTACAGATTTTATAATTTGGGGGAAGAAAAATTTTA
CTAAATGATCTTTTAATGGAAACTCTACAAGAACCAGAATCTTTGCTTTGTTCACTTATGTATCCATTCCTAGGCCTAGAAAAATGTCTG
ACGCATAGCAGCAATTATTCATTGAATAAATGGACCCAGCAATAGTACATTAGCTATGCCATATGCATACATTAAAAATGTAGATTATTG
ACTTTCAAAAGATAATTAATGTAACTTCTTACTGCTTCTGAACATGTTTGTGAGTTATATTGCTGAGGGACCTTTATCTTCTCATTCTTT
CATCTTAATCCAATGTTATTAAAACTGAAACTGAAATCACCAATATTATTCCATATTTAAAAATAACATCTACCTTATAAAAATTATCAT
TGTGCTGCATTTGAGAATAGACTTTTTAGGTAATAATGGTATAATCCATAGGGTTTTTGAGGGCACAGAAGGATTCATGCTAACAGAACA
TTTTATTTTCTATTTTCCAAGAGCTATAAAACATGATATTATATGATACTATAAGGCATATTTTTATTTTCCATAATTTTTTCTAAAAAA
AATTAGTGTTGGTTTTCCATATAACTTTTAACTTTATAAGTAAATATTTGTCTCTTTCAGCTCCAGTTTCATGTGAAATAGAGTTTCCAG
ATTTATGTAGCATGGAAAGTTTTAATACGTCAGTTACTGATTTTTGCCAGTCATTTTCTCAATTATTTACTTCTTTTATCTTTAGTTGAT
TTTTTTTGTAGTGACAAGTTTTGTTTCTATTCTCATTTCCTTTTGTGTATATTCTATGTAGATTTCGTTTTTGGTTACTATGAAAATTAC
ATATAACATCCTGGAGTTATAACATTCTGATTTGAATTTATTTCAACTTAACTTCAATCACATACCAAAATTCTACTGCTATATAGGTCT
ACTCTTTTTAGGTTATTGATGTAACAAATTGTATCTTTATTCATTGTACACCACCTAACAGATTTATAATTACATTTTATGCATTTGTCT

>25482_25482_5_EGFR-SEPT14_EGFR_chr7_55087058_ENST00000442591_SEPT14_chr7_55874951_ENST00000388975_length(amino acids)=189AA_BP=29
MRPSGTAGAALLALLAALCPASRALEEKKVENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSFQEI
FEAKRQEFYDQCQREEEELKQRFMQRVKEKEATFKEAEKELQDKFEHLKMIQQEEIRKLEEEKKQLEGEIIDFYKMKAASEALQTQLSTD

--------------------------------------------------------------
>25482_25482_6_EGFR-SEPT14_EGFR_chr7_55087058_ENST00000455089_SEPT14_chr7_55874951_ENST00000388975_length(transcript)=3196nt_BP=345nt
GTCCGGGCAGCCCCCGGCGCAGCGCGGCCGCAGCAGCCTCCGCCCCCCGCACGGTGTGAGCGCCCGACGCGGCCGAGGCGGCCGGAGTCC
CGAGCTAGCCCCGGCGGCCGCCGCCGCCCAGACCGGACGACAGGCCACCTCGTCGGCGTCCGCCCGAGTCCCCGCCTCGCCGCCAACGCC
ACAACCACCGCGCACGGCCCCCTGACTCCGTCCAGTATTGATCGGGAGAGCCGGAGCGAGCTCTTCGGGGAGCAGCGATGCGACCCTCCG
GGACGGCCGGGGCAGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGTGGAAAATGAAAATC
ACTGTGACTTCGTTAAGCTCCGAGATATGCTTCTTTGTACCAATATGGAAAATCTAAAAGAAAAAACCCACACTCAGCACTATGAATGTT
ATAGGTACCAAAAACTGCAGAAAATGGGCTTTACAGATGTGGGTCCAAACAACCAGCCAGTTAGTTTTCAAGAAATCTTTGAAGCCAAAA
GACAAGAGTTCTATGATCAATGTCAGAGGGAAGAAGAAGAGTTGAAACAGAGATTTATGCAGCGAGTCAAGGAGAAAGAAGCAACATTTA
AAGAAGCTGAAAAAGAGCTGCAGGACAAGTTCGAGCATCTTAAAATGATTCAACAGGAGGAGATAAGGAAGCTCGAGGAAGAGAAAAAAC
AACTGGAAGGAGAAATCATAGATTTTTATAAAATGAAAGCTGCCTCCGAAGCACTGCAGACTCAGCTGAGCACCGATACAAAGAAAGACA
AACATCGTAAGAAATAATAGTTTCTCTTACTATTCTGAGAGCCCTATCATTCTACATCGCAACTTCCTGTGAGATTGTCTTTGTAGCATT
TAACTCTGAAGTTCTCATTTTAAAAATTGGCTTGCTTATTGTATATTTTCCCCAACTAAAGTGTGAACTCCTAGCGGGGTGTGGTGGCTC
ATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGACCACCTGAGGTCAGGAGTTCAAAACCAGCCTGACCAAAATGATGAAAC
CCTGCCTCTACTAAAAATACAAAAATTAGCTGGGTTTGGTGGCCGGTACCTGTAATCCCAGCCACTTGGGAGGCTGAGGCAGGAGAATCA
CTTGAACCCCGGAGGTGGAGGTTGCAGTGAGCCAAGATCTCACCATTGTACTCCAGCCTGGGTGACAAGAGCAAAACTCCGCCTCAAAAA
AAAAAAAAAAAAAAAAAGTATGAACTCCCAGAAGGCAGATCCTGTGTCCCTCTTTTCAGATTCTGTATCTTGGCACTTAGGACGTACACT
AACACAAATATGACTTTCAATCAATATTTGCCAAAATGAAAAAACAAAAGAAACACGTAGCATCATGTAAAAGGAGCTGGTTAGGTGGAG
AAATTTATTTACCATAGTCCTGCTTTTGGATCCAGTAGTGACTTTTAACTTTTATATCCAAATAGAAGCTGGAGGCTTTGTTGGGGACTC
ATAGGCATAAAATGTTAAGTTATACAAATCTAATTAATAGGCCTATTTTCCTTTTTAAGTTCTACTACTGATAATTTCTTGACAGTTTTT
ATGATAAAAGGTTGGAATTTGATAAGAACTCCCATGCTTTTGTGTCAGACTTAAAACTGATATTAGAATAAAGAATTCAAAAGCTAGAGA
AAGAGTTGCATTTGAATGATAATATTATGTGTTACAGATTTGGGGTATATGCCAAAGTTATCAAAGTTGTAGAAAATAAGGCCAGGTGTG
GTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGCGGTCAGGAGCTTGAGAACAGCCCGGCCAACATG
ACGAAACCCCATCTCTACTAATAATACAAAAGTTAGCCGGGTGTGGTGTTGTGCACCTGTAGTCCCTGCTACTCGGAAAGCTGAGGCAGG
AGAATCGCTTGTAGCCAGGAGGCAGAGGTTGTAGTGAGCAGAGATTGCGCCACTGCACTCCAGCCTGGGTGACAGAGCGCTGAGTCACCA
CACCTGGTATAAGCCACTGTGCCTGACCCACAATGACTTTTATACATATTGTTAAATCATCTTACAGATTTTATAATTTGGGGGAAGAAA
AATTTTACTAAATGATCTTTTAATGGAAACTCTACAAGAACCAGAATCTTTGCTTTGTTCACTTATGTATCCATTCCTAGGCCTAGAAAA
ATGTCTGACGCATAGCAGCAATTATTCATTGAATAAATGGACCCAGCAATAGTACATTAGCTATGCCATATGCATACATTAAAAATGTAG
ATTATTGACTTTCAAAAGATAATTAATGTAACTTCTTACTGCTTCTGAACATGTTTGTGAGTTATATTGCTGAGGGACCTTTATCTTCTC
ATTCTTTCATCTTAATCCAATGTTATTAAAACTGAAACTGAAATCACCAATATTATTCCATATTTAAAAATAACATCTACCTTATAAAAA
TTATCATTGTGCTGCATTTGAGAATAGACTTTTTAGGTAATAATGGTATAATCCATAGGGTTTTTGAGGGCACAGAAGGATTCATGCTAA
CAGAACATTTTATTTTCTATTTTCCAAGAGCTATAAAACATGATATTATATGATACTATAAGGCATATTTTTATTTTCCATAATTTTTTC
TAAAAAAAATTAGTGTTGGTTTTCCATATAACTTTTAACTTTATAAGTAAATATTTGTCTCTTTCAGCTCCAGTTTCATGTGAAATAGAG
TTTCCAGATTTATGTAGCATGGAAAGTTTTAATACGTCAGTTACTGATTTTTGCCAGTCATTTTCTCAATTATTTACTTCTTTTATCTTT
AGTTGATTTTTTTTGTAGTGACAAGTTTTGTTTCTATTCTCATTTCCTTTTGTGTATATTCTATGTAGATTTCGTTTTTGGTTACTATGA
AAATTACATATAACATCCTGGAGTTATAACATTCTGATTTGAATTTATTTCAACTTAACTTCAATCACATACCAAAATTCTACTGCTATA
TAGGTCTACTCTTTTTAGGTTATTGATGTAACAAATTGTATCTTTATTCATTGTACACCACCTAACAGATTTATAATTACATTTTATGCA

>25482_25482_6_EGFR-SEPT14_EGFR_chr7_55087058_ENST00000455089_SEPT14_chr7_55874951_ENST00000388975_length(amino acids)=189AA_BP=29
MRPSGTAGAALLALLAALCPASRALEEKKVENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSFQEI
FEAKRQEFYDQCQREEEELKQRFMQRVKEKEATFKEAEKELQDKFEHLKMIQQEEIRKLEEEKKQLEGEIIDFYKMKAASEALQTQLSTD

--------------------------------------------------------------
>25482_25482_7_EGFR-SEPT14_EGFR_chr7_55268106_ENST00000275493_SEPT14_chr7_55886916_ENST00000388975_length(transcript)=6071nt_BP=3123nt
GCCGGAGTCCCGAGCTAGCCCCGGCGGCCGCCGCCGCCCAGACCGGACGACAGGCCACCTCGTCGGCGTCCGCCCGAGTCCCCGCCTCGC
CGCCAACGCCACAACCACCGCGCACGGCCCCCTGACTCCGTCCAGTATTGATCGGGAGAGCCGGAGCGAGCTCTTCGGGGAGCAGCGATG
CGACCCTCCGGGACGGCCGGGGCAGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGTTTGC
CAAGGCACGAGTAACAAGCTCACGCAGTTGGGCACTTTTGAAGATCATTTTCTCAGCCTCCAGAGGATGTTCAATAACTGTGAGGTGGTC
CTTGGGAATTTGGAAATTACCTATGTGCAGAGGAATTATGATCTTTCCTTCTTAAAGACCATCCAGGAGGTGGCTGGTTATGTCCTCATT
GCCCTCAACACAGTGGAGCGAATTCCTTTGGAAAACCTGCAGATCATCAGAGGAAATATGTACTACGAAAATTCCTATGCCTTAGCAGTC
TTATCTAACTATGATGCAAATAAAACCGGACTGAAGGAGCTGCCCATGAGAAATTTACAGGAAATCCTGCATGGCGCCGTGCGGTTCAGC
AACAACCCTGCCCTGTGCAACGTGGAGAGCATCCAGTGGCGGGACATAGTCAGCAGTGACTTTCTCAGCAACATGTCGATGGACTTCCAG
AACCACCTGGGCAGCTGCCAAAAGTGTGATCCAAGCTGTCCCAATGGGAGCTGCTGGGGTGCAGGAGAGGAGAACTGCCAGAAACTGACC
AAAATCATCTGTGCCCAGCAGTGCTCCGGGCGCTGCCGTGGCAAGTCCCCCAGTGACTGCTGCCACAACCAGTGTGCTGCAGGCTGCACA
GGCCCCCGGGAGAGCGACTGCCTGGTCTGCCGCAAATTCCGAGACGAAGCCACGTGCAAGGACACCTGCCCCCCACTCATGCTCTACAAC
CCCACCACGTACCAGATGGATGTGAACCCCGAGGGCAAATACAGCTTTGGTGCCACCTGCGTGAAGAAGTGTCCCCGTAATTATGTGGTG
ACAGATCACGGCTCGTGCGTCCGAGCCTGTGGGGCCGACAGCTATGAGATGGAGGAAGACGGCGTCCGCAAGTGTAAGAAGTGCGAAGGG
CCTTGCCGCAAAGTGTGTAACGGAATAGGTATTGGTGAATTTAAAGACTCACTCTCCATAAATGCTACGAATATTAAACACTTCAAAAAC
TGCACCTCCATCAGTGGCGATCTCCACATCCTGCCGGTGGCATTTAGGGGTGACTCCTTCACACATACTCCTCCTCTGGATCCACAGGAA
CTGGATATTCTGAAAACCGTAAAGGAAATCACAGGGTTTTTGCTGATTCAGGCTTGGCCTGAAAACAGGACGGACCTCCATGCCTTTGAG
AACCTAGAAATCATACGCGGCAGGACCAAGCAACATGGTCAGTTTTCTCTTGCAGTCGTCAGCCTGAACATAACATCCTTGGGATTACGC
TCCCTCAAGGAGATAAGTGATGGAGATGTGATAATTTCAGGAAACAAAAATTTGTGCTATGCAAATACAATAAACTGGAAAAAACTGTTT
GGGACCTCCGGTCAGAAAACCAAAATTATAAGCAACAGAGGTGAAAACAGCTGCAAGGCCACAGGCCAGGTCTGCCATGCCTTGTGCTCC
CCCGAGGGCTGCTGGGGCCCGGAGCCCAGGGACTGCGTCTCTTGCCGGAATGTCAGCCGAGGCAGGGAATGCGTGGACAAGTGCAACCTT
CTGGAGGGTGAGCCAAGGGAGTTTGTGGAGAACTCTGAGTGCATACAGTGCCACCCAGAGTGCCTGCCTCAGGCCATGAACATCACCTGC
ACAGGACGGGGACCAGACAACTGTATCCAGTGTGCCCACTACATTGACGGCCCCCACTGCGTCAAGACCTGCCCGGCAGGAGTCATGGGA
GAAAACAACACCCTGGTCTGGAAGTACGCAGACGCCGGCCATGTGTGCCACCTGTGCCATCCAAACTGCACCTACGGATGCACTGGGCCA
GGTCTTGAAGGCTGTCCAACGAATGGGCCTAAGATCCCGTCCATCGCCACTGGGATGGTGGGGGCCCTCCTCTTGCTGCTGGTGGTGGCC
CTGGGGATCGGCCTCTTCATGCGAAGGCGCCACATCGTTCGGAAGCGCACGCTGCGGAGGCTGCTGCAGGAGAGGGAGCTTGTGGAGCCT
CTTACACCCAGTGGAGAAGCTCCCAACCAAGCTCTCTTGAGGATCTTGAAGGAAACTGAATTCAAAAAGATCAAAGTGCTGGGCTCCGGT
GCGTTCGGCACGGTGTATAAGGGACTCTGGATCCCAGAAGGTGAGAAAGTTAAAATTCCCGTCGCTATCAAGGAATTAAGAGAAGCAACA
TCTCCGAAAGCCAACAAGGAAATCCTCGATGAAGCCTACGTGATGGCCAGCGTGGACAACCCCCACGTGTGCCGCCTGCTGGGCATCTGC
CTCACCTCCACCGTGCAGCTCATCACGCAGCTCATGCCCTTCGGCTGCCTCCTGGACTATGTCCGGGAACACAAAGACAATATTGGCTCC
CAGTACCTGCTCAACTGGTGTGTGCAGATCGCAAAGGGCATGAACTACTTGGAGGACCGTCGCTTGGTGCACCGCGACCTGGCAGCCAGG
AACGTACTGGTGAAAACACCGCAGCATGTCAAGATCACAGATTTTGGGCTGGCCAAACTGCTGGGTGCGGAAGAGAAAGAATACCATGCA
GAAGGAGGCAAAGTGCCTATCAAGTGGATGGCATTGGAATCAATTTTACACAGAATCTATACCCACCAGAGTGATGTCTGGAGCTACGGG
GTGACTGTTTGGGAGTTGATGACCTTTGGATCCAAGCCATATGACGGAATCCCTGCCAGCGAGATCTCCTCCATCCTGGAGAAAGGAGAA
CGCCTCCCTCAGCCACCCATATGTACCATCGATGTCTACATGATCATGGTCAAGTGCTGGATGATAGACGCAGATAGTCGCCCAAAGTTC
CGTGAGTTGATCATCGAATTCTCCAAAATGGCCCGAGACCCCCAGCGCTACCTTGTCATTCAGGGGCTGTTACCCTTTGCTGTGGTAGGG
AGTACAGATGAAGTGAAAGTTGGAAAAAGGATGGTCAGAGGCCGTCACTACCCTTGGGGAGTTTTGCAAGTGGAAAATGAAAATCACTGT
GACTTCGTTAAGCTCCGAGATATGCTTCTTTGTACCAATATGGAAAATCTAAAAGAAAAAACCCACACTCAGCACTATGAATGTTATAGG
TACCAAAAACTGCAGAAAATGGGCTTTACAGATGTGGGTCCAAACAACCAGCCAGTTAGTTTTCAAGAAATCTTTGAAGCCAAAAGACAA
GAGTTCTATGATCAATGTCAGAGGGAAGAAGAAGAGTTGAAACAGAGATTTATGCAGCGAGTCAAGGAGAAAGAAGCAACATTTAAAGAA
GCTGAAAAAGAGCTGCAGGACAAGTTCGAGCATCTTAAAATGATTCAACAGGAGGAGATAAGGAAGCTCGAGGAAGAGAAAAAACAACTG
GAAGGAGAAATCATAGATTTTTATAAAATGAAAGCTGCCTCCGAAGCACTGCAGACTCAGCTGAGCACCGATACAAAGAAAGACAAACAT
CGTAAGAAATAATAGTTTCTCTTACTATTCTGAGAGCCCTATCATTCTACATCGCAACTTCCTGTGAGATTGTCTTTGTAGCATTTAACT
CTGAAGTTCTCATTTTAAAAATTGGCTTGCTTATTGTATATTTTCCCCAACTAAAGTGTGAACTCCTAGCGGGGTGTGGTGGCTCATGCC
TGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGACCACCTGAGGTCAGGAGTTCAAAACCAGCCTGACCAAAATGATGAAACCCTGC
CTCTACTAAAAATACAAAAATTAGCTGGGTTTGGTGGCCGGTACCTGTAATCCCAGCCACTTGGGAGGCTGAGGCAGGAGAATCACTTGA
ACCCCGGAGGTGGAGGTTGCAGTGAGCCAAGATCTCACCATTGTACTCCAGCCTGGGTGACAAGAGCAAAACTCCGCCTCAAAAAAAAAA
AAAAAAAAAAAAGTATGAACTCCCAGAAGGCAGATCCTGTGTCCCTCTTTTCAGATTCTGTATCTTGGCACTTAGGACGTACACTAACAC
AAATATGACTTTCAATCAATATTTGCCAAAATGAAAAAACAAAAGAAACACGTAGCATCATGTAAAAGGAGCTGGTTAGGTGGAGAAATT
TATTTACCATAGTCCTGCTTTTGGATCCAGTAGTGACTTTTAACTTTTATATCCAAATAGAAGCTGGAGGCTTTGTTGGGGACTCATAGG
CATAAAATGTTAAGTTATACAAATCTAATTAATAGGCCTATTTTCCTTTTTAAGTTCTACTACTGATAATTTCTTGACAGTTTTTATGAT
AAAAGGTTGGAATTTGATAAGAACTCCCATGCTTTTGTGTCAGACTTAAAACTGATATTAGAATAAAGAATTCAAAAGCTAGAGAAAGAG
TTGCATTTGAATGATAATATTATGTGTTACAGATTTGGGGTATATGCCAAAGTTATCAAAGTTGTAGAAAATAAGGCCAGGTGTGGTGGC
TCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGCGGTCAGGAGCTTGAGAACAGCCCGGCCAACATGACGAA
ACCCCATCTCTACTAATAATACAAAAGTTAGCCGGGTGTGGTGTTGTGCACCTGTAGTCCCTGCTACTCGGAAAGCTGAGGCAGGAGAAT
CGCTTGTAGCCAGGAGGCAGAGGTTGTAGTGAGCAGAGATTGCGCCACTGCACTCCAGCCTGGGTGACAGAGCGCTGAGTCACCACACCT
GGTATAAGCCACTGTGCCTGACCCACAATGACTTTTATACATATTGTTAAATCATCTTACAGATTTTATAATTTGGGGGAAGAAAAATTT
TACTAAATGATCTTTTAATGGAAACTCTACAAGAACCAGAATCTTTGCTTTGTTCACTTATGTATCCATTCCTAGGCCTAGAAAAATGTC
TGACGCATAGCAGCAATTATTCATTGAATAAATGGACCCAGCAATAGTACATTAGCTATGCCATATGCATACATTAAAAATGTAGATTAT
TGACTTTCAAAAGATAATTAATGTAACTTCTTACTGCTTCTGAACATGTTTGTGAGTTATATTGCTGAGGGACCTTTATCTTCTCATTCT
TTCATCTTAATCCAATGTTATTAAAACTGAAACTGAAATCACCAATATTATTCCATATTTAAAAATAACATCTACCTTATAAAAATTATC
ATTGTGCTGCATTTGAGAATAGACTTTTTAGGTAATAATGGTATAATCCATAGGGTTTTTGAGGGCACAGAAGGATTCATGCTAACAGAA
CATTTTATTTTCTATTTTCCAAGAGCTATAAAACATGATATTATATGATACTATAAGGCATATTTTTATTTTCCATAATTTTTTCTAAAA
AAAATTAGTGTTGGTTTTCCATATAACTTTTAACTTTATAAGTAAATATTTGTCTCTTTCAGCTCCAGTTTCATGTGAAATAGAGTTTCC
AGATTTATGTAGCATGGAAAGTTTTAATACGTCAGTTACTGATTTTTGCCAGTCATTTTCTCAATTATTTACTTCTTTTATCTTTAGTTG
ATTTTTTTTGTAGTGACAAGTTTTGTTTCTATTCTCATTTCCTTTTGTGTATATTCTATGTAGATTTCGTTTTTGGTTACTATGAAAATT
ACATATAACATCCTGGAGTTATAACATTCTGATTTGAATTTATTTCAACTTAACTTCAATCACATACCAAAATTCTACTGCTATATAGGT
CTACTCTTTTTAGGTTATTGATGTAACAAATTGTATCTTTATTCATTGTACACCACCTAACAGATTTATAATTACATTTTATGCATTTGT

>25482_25482_7_EGFR-SEPT14_EGFR_chr7_55268106_ENST00000275493_SEPT14_chr7_55886916_ENST00000388975_length(amino acids)=1174AA_BP=978
MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVL
IALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDF
QNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLY
NPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFK
NCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGL
RSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCN
LLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTG
PGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGS
GAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIG
SQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSY
GVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGLLPFAVV
GSTDEVKVGKRMVRGRHYPWGVLQVENENHCDFVKLRDMLLCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSFQEIFEAKR
QEFYDQCQREEEELKQRFMQRVKEKEATFKEAEKELQDKFEHLKMIQQEEIRKLEEEKKQLEGEIIDFYKMKAASEALQTQLSTDTKKDK

--------------------------------------------------------------
>25482_25482_8_EGFR-SEPT14_EGFR_chr7_55268106_ENST00000454757_SEPT14_chr7_55886916_ENST00000388975_length(transcript)=5918nt_BP=2970nt
ACTGGACTTCAGAACAAGAGGGAGCTCTGGGCTGCTGGCTGGTTGTGCATTTGCTGTGGGTTCCCTCCGGCAGGCGACCTCTCCGCGCTG
AGAAGGTTATCCGGATAACCAATTTGCCAAGGCACGAGTAACAAGCTCACGCAGTTGGGCACTTTTGAAGATCATTTTCTCAGCCTCCAG
AGGATGTTCAATAACTGTGAGGTGGTCCTTGGGAATTTGGAAATTACCTATGTGCAGAGGAATTATGATCTTTCCTTCTTAAAGACCATC
CAGGAGGTGGCTGGTTATGTCCTCATTGCCCTCAACACAGTGGAGCGAATTCCTTTGGAAAACCTGCAGATCATCAGAGGAAATATGTAC
TACGAAAATTCCTATGCCTTAGCAGTCTTATCTAACTATGATGCAAATAAAACCGGACTGAAGGAGCTGCCCATGAGAAATTTACAGGAA
ATCCTGCATGGCGCCGTGCGGTTCAGCAACAACCCTGCCCTGTGCAACGTGGAGAGCATCCAGTGGCGGGACATAGTCAGCAGTGACTTT
CTCAGCAACATGTCGATGGACTTCCAGAACCACCTGGGCAGCTGCCAAAAGTGTGATCCAAGCTGTCCCAATGGGAGCTGCTGGGGTGCA
GGAGAGGAGAACTGCCAGAAACTGACCAAAATCATCTGTGCCCAGCAGTGCTCCGGGCGCTGCCGTGGCAAGTCCCCCAGTGACTGCTGC
CACAACCAGTGTGCTGCAGGCTGCACAGGCCCCCGGGAGAGCGACTGCCTGGTCTGCCGCAAATTCCGAGACGAAGCCACGTGCAAGGAC
ACCTGCCCCCCACTCATGCTCTACAACCCCACCACGTACCAGATGGATGTGAACCCCGAGGGCAAATACAGCTTTGGTGCCACCTGCGTG
AAGAAGTGTCCCCGTAATTATGTGGTGACAGATCACGGCTCGTGCGTCCGAGCCTGTGGGGCCGACAGCTATGAGATGGAGGAAGACGGC
GTCCGCAAGTGTAAGAAGTGCGAAGGGCCTTGCCGCAAAGTGTGTAACGGAATAGGTATTGGTGAATTTAAAGACTCACTCTCCATAAAT
GCTACGAATATTAAACACTTCAAAAACTGCACCTCCATCAGTGGCGATCTCCACATCCTGCCGGTGGCATTTAGGGGTGACTCCTTCACA
CATACTCCTCCTCTGGATCCACAGGAACTGGATATTCTGAAAACCGTAAAGGAAATCACAGGGTTTTTGCTGATTCAGGCTTGGCCTGAA
AACAGGACGGACCTCCATGCCTTTGAGAACCTAGAAATCATACGCGGCAGGACCAAGCAACATGGTCAGTTTTCTCTTGCAGTCGTCAGC
CTGAACATAACATCCTTGGGATTACGCTCCCTCAAGGAGATAAGTGATGGAGATGTGATAATTTCAGGAAACAAAAATTTGTGCTATGCA
AATACAATAAACTGGAAAAAACTGTTTGGGACCTCCGGTCAGAAAACCAAAATTATAAGCAACAGAGGTGAAAACAGCTGCAAGGCCACA
GGCCAGGTCTGCCATGCCTTGTGCTCCCCCGAGGGCTGCTGGGGCCCGGAGCCCAGGGACTGCGTCTCTTGCCGGAATGTCAGCCGAGGC
AGGGAATGCGTGGACAAGTGCAACCTTCTGGAGGGTGAGCCAAGGGAGTTTGTGGAGAACTCTGAGTGCATACAGTGCCACCCAGAGTGC
CTGCCTCAGGCCATGAACATCACCTGCACAGGACGGGGACCAGACAACTGTATCCAGTGTGCCCACTACATTGACGGCCCCCACTGCGTC
AAGACCTGCCCGGCAGGAGTCATGGGAGAAAACAACACCCTGGTCTGGAAGTACGCAGACGCCGGCCATGTGTGCCACCTGTGCCATCCA
AACTGCACCTACGGATGCACTGGGCCAGGTCTTGAAGGCTGTCCAACGAATGGGCCTAAGATCCCGTCCATCGCCACTGGGATGGTGGGG
GCCCTCCTCTTGCTGCTGGTGGTGGCCCTGGGGATCGGCCTCTTCATGCGAAGGCGCCACATCGTTCGGAAGCGCACGCTGCGGAGGCTG
CTGCAGGAGAGGGAGCTTGTGGAGCCTCTTACACCCAGTGGAGAAGCTCCCAACCAAGCTCTCTTGAGGATCTTGAAGGAAACTGAATTC
AAAAAGATCAAAGTGCTGGGCTCCGGTGCGTTCGGCACGGTGTATAAGGGACTCTGGATCCCAGAAGGTGAGAAAGTTAAAATTCCCGTC
GCTATCAAGGAATTAAGAGAAGCAACATCTCCGAAAGCCAACAAGGAAATCCTCGATGAAGCCTACGTGATGGCCAGCGTGGACAACCCC
CACGTGTGCCGCCTGCTGGGCATCTGCCTCACCTCCACCGTGCAGCTCATCACGCAGCTCATGCCCTTCGGCTGCCTCCTGGACTATGTC
CGGGAACACAAAGACAATATTGGCTCCCAGTACCTGCTCAACTGGTGTGTGCAGATCGCAAAGGGCATGAACTACTTGGAGGACCGTCGC
TTGGTGCACCGCGACCTGGCAGCCAGGAACGTACTGGTGAAAACACCGCAGCATGTCAAGATCACAGATTTTGGGCTGGCCAAACTGCTG
GGTGCGGAAGAGAAAGAATACCATGCAGAAGGAGGCAAAGTGCCTATCAAGTGGATGGCATTGGAATCAATTTTACACAGAATCTATACC
CACCAGAGTGATGTCTGGAGCTACGGGGTGACTGTTTGGGAGTTGATGACCTTTGGATCCAAGCCATATGACGGAATCCCTGCCAGCGAG
ATCTCCTCCATCCTGGAGAAAGGAGAACGCCTCCCTCAGCCACCCATATGTACCATCGATGTCTACATGATCATGGTCAAGTGCTGGATG
ATAGACGCAGATAGTCGCCCAAAGTTCCGTGAGTTGATCATCGAATTCTCCAAAATGGCCCGAGACCCCCAGCGCTACCTTGTCATTCAG
GGGCTGTTACCCTTTGCTGTGGTAGGGAGTACAGATGAAGTGAAAGTTGGAAAAAGGATGGTCAGAGGCCGTCACTACCCTTGGGGAGTT
TTGCAAGTGGAAAATGAAAATCACTGTGACTTCGTTAAGCTCCGAGATATGCTTCTTTGTACCAATATGGAAAATCTAAAAGAAAAAACC
CACACTCAGCACTATGAATGTTATAGGTACCAAAAACTGCAGAAAATGGGCTTTACAGATGTGGGTCCAAACAACCAGCCAGTTAGTTTT
CAAGAAATCTTTGAAGCCAAAAGACAAGAGTTCTATGATCAATGTCAGAGGGAAGAAGAAGAGTTGAAACAGAGATTTATGCAGCGAGTC
AAGGAGAAAGAAGCAACATTTAAAGAAGCTGAAAAAGAGCTGCAGGACAAGTTCGAGCATCTTAAAATGATTCAACAGGAGGAGATAAGG
AAGCTCGAGGAAGAGAAAAAACAACTGGAAGGAGAAATCATAGATTTTTATAAAATGAAAGCTGCCTCCGAAGCACTGCAGACTCAGCTG
AGCACCGATACAAAGAAAGACAAACATCGTAAGAAATAATAGTTTCTCTTACTATTCTGAGAGCCCTATCATTCTACATCGCAACTTCCT
GTGAGATTGTCTTTGTAGCATTTAACTCTGAAGTTCTCATTTTAAAAATTGGCTTGCTTATTGTATATTTTCCCCAACTAAAGTGTGAAC
TCCTAGCGGGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGACCACCTGAGGTCAGGAGTTCAAAACC
AGCCTGACCAAAATGATGAAACCCTGCCTCTACTAAAAATACAAAAATTAGCTGGGTTTGGTGGCCGGTACCTGTAATCCCAGCCACTTG
GGAGGCTGAGGCAGGAGAATCACTTGAACCCCGGAGGTGGAGGTTGCAGTGAGCCAAGATCTCACCATTGTACTCCAGCCTGGGTGACAA
GAGCAAAACTCCGCCTCAAAAAAAAAAAAAAAAAAAAAAGTATGAACTCCCAGAAGGCAGATCCTGTGTCCCTCTTTTCAGATTCTGTAT
CTTGGCACTTAGGACGTACACTAACACAAATATGACTTTCAATCAATATTTGCCAAAATGAAAAAACAAAAGAAACACGTAGCATCATGT
AAAAGGAGCTGGTTAGGTGGAGAAATTTATTTACCATAGTCCTGCTTTTGGATCCAGTAGTGACTTTTAACTTTTATATCCAAATAGAAG
CTGGAGGCTTTGTTGGGGACTCATAGGCATAAAATGTTAAGTTATACAAATCTAATTAATAGGCCTATTTTCCTTTTTAAGTTCTACTAC
TGATAATTTCTTGACAGTTTTTATGATAAAAGGTTGGAATTTGATAAGAACTCCCATGCTTTTGTGTCAGACTTAAAACTGATATTAGAA
TAAAGAATTCAAAAGCTAGAGAAAGAGTTGCATTTGAATGATAATATTATGTGTTACAGATTTGGGGTATATGCCAAAGTTATCAAAGTT
GTAGAAAATAAGGCCAGGTGTGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGCGGTCAGGAGCT
TGAGAACAGCCCGGCCAACATGACGAAACCCCATCTCTACTAATAATACAAAAGTTAGCCGGGTGTGGTGTTGTGCACCTGTAGTCCCTG
CTACTCGGAAAGCTGAGGCAGGAGAATCGCTTGTAGCCAGGAGGCAGAGGTTGTAGTGAGCAGAGATTGCGCCACTGCACTCCAGCCTGG
GTGACAGAGCGCTGAGTCACCACACCTGGTATAAGCCACTGTGCCTGACCCACAATGACTTTTATACATATTGTTAAATCATCTTACAGA
TTTTATAATTTGGGGGAAGAAAAATTTTACTAAATGATCTTTTAATGGAAACTCTACAAGAACCAGAATCTTTGCTTTGTTCACTTATGT
ATCCATTCCTAGGCCTAGAAAAATGTCTGACGCATAGCAGCAATTATTCATTGAATAAATGGACCCAGCAATAGTACATTAGCTATGCCA
TATGCATACATTAAAAATGTAGATTATTGACTTTCAAAAGATAATTAATGTAACTTCTTACTGCTTCTGAACATGTTTGTGAGTTATATT
GCTGAGGGACCTTTATCTTCTCATTCTTTCATCTTAATCCAATGTTATTAAAACTGAAACTGAAATCACCAATATTATTCCATATTTAAA
AATAACATCTACCTTATAAAAATTATCATTGTGCTGCATTTGAGAATAGACTTTTTAGGTAATAATGGTATAATCCATAGGGTTTTTGAG
GGCACAGAAGGATTCATGCTAACAGAACATTTTATTTTCTATTTTCCAAGAGCTATAAAACATGATATTATATGATACTATAAGGCATAT
TTTTATTTTCCATAATTTTTTCTAAAAAAAATTAGTGTTGGTTTTCCATATAACTTTTAACTTTATAAGTAAATATTTGTCTCTTTCAGC
TCCAGTTTCATGTGAAATAGAGTTTCCAGATTTATGTAGCATGGAAAGTTTTAATACGTCAGTTACTGATTTTTGCCAGTCATTTTCTCA
ATTATTTACTTCTTTTATCTTTAGTTGATTTTTTTTGTAGTGACAAGTTTTGTTTCTATTCTCATTTCCTTTTGTGTATATTCTATGTAG
ATTTCGTTTTTGGTTACTATGAAAATTACATATAACATCCTGGAGTTATAACATTCTGATTTGAATTTATTTCAACTTAACTTCAATCAC
ATACCAAAATTCTACTGCTATATAGGTCTACTCTTTTTAGGTTATTGATGTAACAAATTGTATCTTTATTCATTGTACACCACCTAACAG

>25482_25482_8_EGFR-SEPT14_EGFR_chr7_55268106_ENST00000454757_SEPT14_chr7_55886916_ENST00000388975_length(amino acids)=1134AA_BP=938
MGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKT
GLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCS
GRCRGKSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRA
CGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKE
ITGFLLIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKI
ISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCI
QCAHYIDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRR
RHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEIL
DEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQH
VKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICT
IDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGLLPFAVVGSTDEVKVGKRMVRGRHYPWGVLQVENENHCDFVKLRDML
LCTNMENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSFQEIFEAKRQEFYDQCQREEEELKQRFMQRVKEKEATFKEAEKELQDKF

--------------------------------------------------------------
>25482_25482_9_EGFR-SEPT14_EGFR_chr7_55268106_ENST00000455089_SEPT14_chr7_55886916_ENST00000388975_length(transcript)=6016nt_BP=3068nt
GTCCGGGCAGCCCCCGGCGCAGCGCGGCCGCAGCAGCCTCCGCCCCCCGCACGGTGTGAGCGCCCGACGCGGCCGAGGCGGCCGGAGTCC
CGAGCTAGCCCCGGCGGCCGCCGCCGCCCAGACCGGACGACAGGCCACCTCGTCGGCGTCCGCCCGAGTCCCCGCCTCGCCGCCAACGCC
ACAACCACCGCGCACGGCCCCCTGACTCCGTCCAGTATTGATCGGGAGAGCCGGAGCGAGCTCTTCGGGGAGCAGCGATGCGACCCTCCG
GGACGGCCGGGGCAGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGTTTGCCAAGGCACGA
GTAACAAGCTCACGCAGTTGGGCACTTTTGAAGATCATTTTCTCAGCCTCCAGAGGATGTTCAATAACTGTGAGGTGGTCCTTGGGAATT
TGGAAATTACCTATGTGCAGAGGAATTATGATCTTTCCTTCTTAAAGACCATCCAGGAGGTGGCTGGTTATGTCCTCATTGCCCTCAACA
CAGTGGAGCGAATTCCTTTGGAAAACCTGCAGATCATCAGAGGAAATATGTACTACGAAAATTCCTATGCCTTAGCAGTCTTATCTAACT
ATGATGCAAATAAAACCGGACTGAAGGAGCTGCCCATGAGAAATTTACAGGGCCAAAAGTGTGATCCAAGCTGTCCCAATGGGAGCTGCT
GGGGTGCAGGAGAGGAGAACTGCCAGAAACTGACCAAAATCATCTGTGCCCAGCAGTGCTCCGGGCGCTGCCGTGGCAAGTCCCCCAGTG
ACTGCTGCCACAACCAGTGTGCTGCAGGCTGCACAGGCCCCCGGGAGAGCGACTGCCTGGTCTGCCGCAAATTCCGAGACGAAGCCACGT
GCAAGGACACCTGCCCCCCACTCATGCTCTACAACCCCACCACGTACCAGATGGATGTGAACCCCGAGGGCAAATACAGCTTTGGTGCCA
CCTGCGTGAAGAAGTGTCCCCGTAATTATGTGGTGACAGATCACGGCTCGTGCGTCCGAGCCTGTGGGGCCGACAGCTATGAGATGGAGG
AAGACGGCGTCCGCAAGTGTAAGAAGTGCGAAGGGCCTTGCCGCAAAGTGTGTAACGGAATAGGTATTGGTGAATTTAAAGACTCACTCT
CCATAAATGCTACGAATATTAAACACTTCAAAAACTGCACCTCCATCAGTGGCGATCTCCACATCCTGCCGGTGGCATTTAGGGGTGACT
CCTTCACACATACTCCTCCTCTGGATCCACAGGAACTGGATATTCTGAAAACCGTAAAGGAAATCACAGGGTTTTTGCTGATTCAGGCTT
GGCCTGAAAACAGGACGGACCTCCATGCCTTTGAGAACCTAGAAATCATACGCGGCAGGACCAAGCAACATGGTCAGTTTTCTCTTGCAG
TCGTCAGCCTGAACATAACATCCTTGGGATTACGCTCCCTCAAGGAGATAAGTGATGGAGATGTGATAATTTCAGGAAACAAAAATTTGT
GCTATGCAAATACAATAAACTGGAAAAAACTGTTTGGGACCTCCGGTCAGAAAACCAAAATTATAAGCAACAGAGGTGAAAACAGCTGCA
AGGCCACAGGCCAGGTCTGCCATGCCTTGTGCTCCCCCGAGGGCTGCTGGGGCCCGGAGCCCAGGGACTGCGTCTCTTGCCGGAATGTCA
GCCGAGGCAGGGAATGCGTGGACAAGTGCAACCTTCTGGAGGGTGAGCCAAGGGAGTTTGTGGAGAACTCTGAGTGCATACAGTGCCACC
CAGAGTGCCTGCCTCAGGCCATGAACATCACCTGCACAGGACGGGGACCAGACAACTGTATCCAGTGTGCCCACTACATTGACGGCCCCC
ACTGCGTCAAGACCTGCCCGGCAGGAGTCATGGGAGAAAACAACACCCTGGTCTGGAAGTACGCAGACGCCGGCCATGTGTGCCACCTGT
GCCATCCAAACTGCACCTACGGATGCACTGGGCCAGGTCTTGAAGGCTGTCCAACGAATGGGCCTAAGATCCCGTCCATCGCCACTGGGA
TGGTGGGGGCCCTCCTCTTGCTGCTGGTGGTGGCCCTGGGGATCGGCCTCTTCATGCGAAGGCGCCACATCGTTCGGAAGCGCACGCTGC
GGAGGCTGCTGCAGGAGAGGGAGCTTGTGGAGCCTCTTACACCCAGTGGAGAAGCTCCCAACCAAGCTCTCTTGAGGATCTTGAAGGAAA
CTGAATTCAAAAAGATCAAAGTGCTGGGCTCCGGTGCGTTCGGCACGGTGTATAAGGGACTCTGGATCCCAGAAGGTGAGAAAGTTAAAA
TTCCCGTCGCTATCAAGGAATTAAGAGAAGCAACATCTCCGAAAGCCAACAAGGAAATCCTCGATGAAGCCTACGTGATGGCCAGCGTGG
ACAACCCCCACGTGTGCCGCCTGCTGGGCATCTGCCTCACCTCCACCGTGCAGCTCATCACGCAGCTCATGCCCTTCGGCTGCCTCCTGG
ACTATGTCCGGGAACACAAAGACAATATTGGCTCCCAGTACCTGCTCAACTGGTGTGTGCAGATCGCAAAGGGCATGAACTACTTGGAGG
ACCGTCGCTTGGTGCACCGCGACCTGGCAGCCAGGAACGTACTGGTGAAAACACCGCAGCATGTCAAGATCACAGATTTTGGGCTGGCCA
AACTGCTGGGTGCGGAAGAGAAAGAATACCATGCAGAAGGAGGCAAAGTGCCTATCAAGTGGATGGCATTGGAATCAATTTTACACAGAA
TCTATACCCACCAGAGTGATGTCTGGAGCTACGGGGTGACTGTTTGGGAGTTGATGACCTTTGGATCCAAGCCATATGACGGAATCCCTG
CCAGCGAGATCTCCTCCATCCTGGAGAAAGGAGAACGCCTCCCTCAGCCACCCATATGTACCATCGATGTCTACATGATCATGGTCAAGT
GCTGGATGATAGACGCAGATAGTCGCCCAAAGTTCCGTGAGTTGATCATCGAATTCTCCAAAATGGCCCGAGACCCCCAGCGCTACCTTG
TCATTCAGGGGCTGTTACCCTTTGCTGTGGTAGGGAGTACAGATGAAGTGAAAGTTGGAAAAAGGATGGTCAGAGGCCGTCACTACCCTT
GGGGAGTTTTGCAAGTGGAAAATGAAAATCACTGTGACTTCGTTAAGCTCCGAGATATGCTTCTTTGTACCAATATGGAAAATCTAAAAG
AAAAAACCCACACTCAGCACTATGAATGTTATAGGTACCAAAAACTGCAGAAAATGGGCTTTACAGATGTGGGTCCAAACAACCAGCCAG
TTAGTTTTCAAGAAATCTTTGAAGCCAAAAGACAAGAGTTCTATGATCAATGTCAGAGGGAAGAAGAAGAGTTGAAACAGAGATTTATGC
AGCGAGTCAAGGAGAAAGAAGCAACATTTAAAGAAGCTGAAAAAGAGCTGCAGGACAAGTTCGAGCATCTTAAAATGATTCAACAGGAGG
AGATAAGGAAGCTCGAGGAAGAGAAAAAACAACTGGAAGGAGAAATCATAGATTTTTATAAAATGAAAGCTGCCTCCGAAGCACTGCAGA
CTCAGCTGAGCACCGATACAAAGAAAGACAAACATCGTAAGAAATAATAGTTTCTCTTACTATTCTGAGAGCCCTATCATTCTACATCGC
AACTTCCTGTGAGATTGTCTTTGTAGCATTTAACTCTGAAGTTCTCATTTTAAAAATTGGCTTGCTTATTGTATATTTTCCCCAACTAAA
GTGTGAACTCCTAGCGGGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGACCACCTGAGGTCAGGAGT
TCAAAACCAGCCTGACCAAAATGATGAAACCCTGCCTCTACTAAAAATACAAAAATTAGCTGGGTTTGGTGGCCGGTACCTGTAATCCCA
GCCACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCCGGAGGTGGAGGTTGCAGTGAGCCAAGATCTCACCATTGTACTCCAGCCTG
GGTGACAAGAGCAAAACTCCGCCTCAAAAAAAAAAAAAAAAAAAAAAGTATGAACTCCCAGAAGGCAGATCCTGTGTCCCTCTTTTCAGA
TTCTGTATCTTGGCACTTAGGACGTACACTAACACAAATATGACTTTCAATCAATATTTGCCAAAATGAAAAAACAAAAGAAACACGTAG
CATCATGTAAAAGGAGCTGGTTAGGTGGAGAAATTTATTTACCATAGTCCTGCTTTTGGATCCAGTAGTGACTTTTAACTTTTATATCCA
AATAGAAGCTGGAGGCTTTGTTGGGGACTCATAGGCATAAAATGTTAAGTTATACAAATCTAATTAATAGGCCTATTTTCCTTTTTAAGT
TCTACTACTGATAATTTCTTGACAGTTTTTATGATAAAAGGTTGGAATTTGATAAGAACTCCCATGCTTTTGTGTCAGACTTAAAACTGA
TATTAGAATAAAGAATTCAAAAGCTAGAGAAAGAGTTGCATTTGAATGATAATATTATGTGTTACAGATTTGGGGTATATGCCAAAGTTA
TCAAAGTTGTAGAAAATAAGGCCAGGTGTGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGCGGT
CAGGAGCTTGAGAACAGCCCGGCCAACATGACGAAACCCCATCTCTACTAATAATACAAAAGTTAGCCGGGTGTGGTGTTGTGCACCTGT
AGTCCCTGCTACTCGGAAAGCTGAGGCAGGAGAATCGCTTGTAGCCAGGAGGCAGAGGTTGTAGTGAGCAGAGATTGCGCCACTGCACTC
CAGCCTGGGTGACAGAGCGCTGAGTCACCACACCTGGTATAAGCCACTGTGCCTGACCCACAATGACTTTTATACATATTGTTAAATCAT
CTTACAGATTTTATAATTTGGGGGAAGAAAAATTTTACTAAATGATCTTTTAATGGAAACTCTACAAGAACCAGAATCTTTGCTTTGTTC
ACTTATGTATCCATTCCTAGGCCTAGAAAAATGTCTGACGCATAGCAGCAATTATTCATTGAATAAATGGACCCAGCAATAGTACATTAG
CTATGCCATATGCATACATTAAAAATGTAGATTATTGACTTTCAAAAGATAATTAATGTAACTTCTTACTGCTTCTGAACATGTTTGTGA
GTTATATTGCTGAGGGACCTTTATCTTCTCATTCTTTCATCTTAATCCAATGTTATTAAAACTGAAACTGAAATCACCAATATTATTCCA
TATTTAAAAATAACATCTACCTTATAAAAATTATCATTGTGCTGCATTTGAGAATAGACTTTTTAGGTAATAATGGTATAATCCATAGGG
TTTTTGAGGGCACAGAAGGATTCATGCTAACAGAACATTTTATTTTCTATTTTCCAAGAGCTATAAAACATGATATTATATGATACTATA
AGGCATATTTTTATTTTCCATAATTTTTTCTAAAAAAAATTAGTGTTGGTTTTCCATATAACTTTTAACTTTATAAGTAAATATTTGTCT
CTTTCAGCTCCAGTTTCATGTGAAATAGAGTTTCCAGATTTATGTAGCATGGAAAGTTTTAATACGTCAGTTACTGATTTTTGCCAGTCA
TTTTCTCAATTATTTACTTCTTTTATCTTTAGTTGATTTTTTTTGTAGTGACAAGTTTTGTTTCTATTCTCATTTCCTTTTGTGTATATT
CTATGTAGATTTCGTTTTTGGTTACTATGAAAATTACATATAACATCCTGGAGTTATAACATTCTGATTTGAATTTATTTCAACTTAACT
TCAATCACATACCAAAATTCTACTGCTATATAGGTCTACTCTTTTTAGGTTATTGATGTAACAAATTGTATCTTTATTCATTGTACACCA

>25482_25482_9_EGFR-SEPT14_EGFR_chr7_55268106_ENST00000455089_SEPT14_chr7_55886916_ENST00000388975_length(amino acids)=1129AA_BP=933
MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVL
IALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQGQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRG
KSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADS
YEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFL
LIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRG
ENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHY
IDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVR
KRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYV
MASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITD
FGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYM
IMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGLLPFAVVGSTDEVKVGKRMVRGRHYPWGVLQVENENHCDFVKLRDMLLCTNM
ENLKEKTHTQHYECYRYQKLQKMGFTDVGPNNQPVSFQEIFEAKRQEFYDQCQREEEELKQRFMQRVKEKEATFKEAEKELQDKFEHLKM

--------------------------------------------------------------
>25482_25482_10_EGFR-SEPT14_EGFR_chr7_55270318_ENST00000455089_SEPT14_chr7_55863785_ENST00000388975_length(transcript)=6284nt_BP=3735nt
GTCCGGGCAGCCCCCGGCGCAGCGCGGCCGCAGCAGCCTCCGCCCCCCGCACGGTGTGAGCGCCCGACGCGGCCGAGGCGGCCGGAGTCC
CGAGCTAGCCCCGGCGGCCGCCGCCGCCCAGACCGGACGACAGGCCACCTCGTCGGCGTCCGCCCGAGTCCCCGCCTCGCCGCCAACGCC
ACAACCACCGCGCACGGCCCCCTGACTCCGTCCAGTATTGATCGGGAGAGCCGGAGCGAGCTCTTCGGGGAGCAGCGATGCGACCCTCCG
GGACGGCCGGGGCAGCGCTCCTGGCGCTGCTGGCTGCGCTCTGCCCGGCGAGTCGGGCTCTGGAGGAAAAGAAAGTTTGCCAAGGCACGA
GTAACAAGCTCACGCAGTTGGGCACTTTTGAAGATCATTTTCTCAGCCTCCAGAGGATGTTCAATAACTGTGAGGTGGTCCTTGGGAATT
TGGAAATTACCTATGTGCAGAGGAATTATGATCTTTCCTTCTTAAAGACCATCCAGGAGGTGGCTGGTTATGTCCTCATTGCCCTCAACA
CAGTGGAGCGAATTCCTTTGGAAAACCTGCAGATCATCAGAGGAAATATGTACTACGAAAATTCCTATGCCTTAGCAGTCTTATCTAACT
ATGATGCAAATAAAACCGGACTGAAGGAGCTGCCCATGAGAAATTTACAGGGCCAAAAGTGTGATCCAAGCTGTCCCAATGGGAGCTGCT
GGGGTGCAGGAGAGGAGAACTGCCAGAAACTGACCAAAATCATCTGTGCCCAGCAGTGCTCCGGGCGCTGCCGTGGCAAGTCCCCCAGTG
ACTGCTGCCACAACCAGTGTGCTGCAGGCTGCACAGGCCCCCGGGAGAGCGACTGCCTGGTCTGCCGCAAATTCCGAGACGAAGCCACGT
GCAAGGACACCTGCCCCCCACTCATGCTCTACAACCCCACCACGTACCAGATGGATGTGAACCCCGAGGGCAAATACAGCTTTGGTGCCA
CCTGCGTGAAGAAGTGTCCCCGTAATTATGTGGTGACAGATCACGGCTCGTGCGTCCGAGCCTGTGGGGCCGACAGCTATGAGATGGAGG
AAGACGGCGTCCGCAAGTGTAAGAAGTGCGAAGGGCCTTGCCGCAAAGTGTGTAACGGAATAGGTATTGGTGAATTTAAAGACTCACTCT
CCATAAATGCTACGAATATTAAACACTTCAAAAACTGCACCTCCATCAGTGGCGATCTCCACATCCTGCCGGTGGCATTTAGGGGTGACT
CCTTCACACATACTCCTCCTCTGGATCCACAGGAACTGGATATTCTGAAAACCGTAAAGGAAATCACAGGGTTTTTGCTGATTCAGGCTT
GGCCTGAAAACAGGACGGACCTCCATGCCTTTGAGAACCTAGAAATCATACGCGGCAGGACCAAGCAACATGGTCAGTTTTCTCTTGCAG
TCGTCAGCCTGAACATAACATCCTTGGGATTACGCTCCCTCAAGGAGATAAGTGATGGAGATGTGATAATTTCAGGAAACAAAAATTTGT
GCTATGCAAATACAATAAACTGGAAAAAACTGTTTGGGACCTCCGGTCAGAAAACCAAAATTATAAGCAACAGAGGTGAAAACAGCTGCA
AGGCCACAGGCCAGGTCTGCCATGCCTTGTGCTCCCCCGAGGGCTGCTGGGGCCCGGAGCCCAGGGACTGCGTCTCTTGCCGGAATGTCA
GCCGAGGCAGGGAATGCGTGGACAAGTGCAACCTTCTGGAGGGTGAGCCAAGGGAGTTTGTGGAGAACTCTGAGTGCATACAGTGCCACC
CAGAGTGCCTGCCTCAGGCCATGAACATCACCTGCACAGGACGGGGACCAGACAACTGTATCCAGTGTGCCCACTACATTGACGGCCCCC
ACTGCGTCAAGACCTGCCCGGCAGGAGTCATGGGAGAAAACAACACCCTGGTCTGGAAGTACGCAGACGCCGGCCATGTGTGCCACCTGT
GCCATCCAAACTGCACCTACGGATGCACTGGGCCAGGTCTTGAAGGCTGTCCAACGAATGGGCCTAAGATCCCGTCCATCGCCACTGGGA
TGGTGGGGGCCCTCCTCTTGCTGCTGGTGGTGGCCCTGGGGATCGGCCTCTTCATGCGAAGGCGCCACATCGTTCGGAAGCGCACGCTGC
GGAGGCTGCTGCAGGAGAGGGAGCTTGTGGAGCCTCTTACACCCAGTGGAGAAGCTCCCAACCAAGCTCTCTTGAGGATCTTGAAGGAAA
CTGAATTCAAAAAGATCAAAGTGCTGGGCTCCGGTGCGTTCGGCACGGTGTATAAGGGACTCTGGATCCCAGAAGGTGAGAAAGTTAAAA
TTCCCGTCGCTATCAAGGAATTAAGAGAAGCAACATCTCCGAAAGCCAACAAGGAAATCCTCGATGAAGCCTACGTGATGGCCAGCGTGG
ACAACCCCCACGTGTGCCGCCTGCTGGGCATCTGCCTCACCTCCACCGTGCAGCTCATCACGCAGCTCATGCCCTTCGGCTGCCTCCTGG
ACTATGTCCGGGAACACAAAGACAATATTGGCTCCCAGTACCTGCTCAACTGGTGTGTGCAGATCGCAAAGGGCATGAACTACTTGGAGG
ACCGTCGCTTGGTGCACCGCGACCTGGCAGCCAGGAACGTACTGGTGAAAACACCGCAGCATGTCAAGATCACAGATTTTGGGCTGGCCA
AACTGCTGGGTGCGGAAGAGAAAGAATACCATGCAGAAGGAGGCAAAGTGCCTATCAAGTGGATGGCATTGGAATCAATTTTACACAGAA
TCTATACCCACCAGAGTGATGTCTGGAGCTACGGGGTGACTGTTTGGGAGTTGATGACCTTTGGATCCAAGCCATATGACGGAATCCCTG
CCAGCGAGATCTCCTCCATCCTGGAGAAAGGAGAACGCCTCCCTCAGCCACCCATATGTACCATCGATGTCTACATGATCATGGTCAAGT
GCTGGATGATAGACGCAGATAGTCGCCCAAAGTTCCGTGAGTTGATCATCGAATTCTCCAAAATGGCCCGAGACCCCCAGCGCTACCTTG
TCATTCAGGGGGATGAAAGAATGCATTTGCCAAGTCCTACAGACTCCAACTTCTACCGTGCCCTGATGGATGAAGAAGACATGGACGACG
TGGTGGATGCCGACGAGTACCTCATCCCACAGCAGGGCTTCTTCAGCAGCCCCTCCACGTCACGGACTCCCCTCCTGAGCTCTCTGAGTG
CAACCAGCAACAATTCCACCGTGGCTTGCATTGATAGAAATGGGGTGAGTGGCTTGTCTGGAAACAGTCCTGCTCCTCAACCTCCTCGAC
CCACTCAGCAGCAGCCAGTCTCCAGTGTCCAAGCCAGGTGCTCCCTCCAGCATCTCCAGAGGGGGAAACAGTGGCAGATTTGCAGACACA
GTGAAGGGCGTAAGGAGCAGATAAACACATGACCGAGCCTGCACAAGCTCTTTGTTGTGTCTGGTTGTTTGCTGTACCTCTGTTGTAAGA
ATGAATCTGCAAAATTTCTAGCTTATGAAGCAAATCACGGACATACACATCTGTGTGTGTGAGTGTTCATGATGTGTGTACATCTGTGTA
TGTGTGTGTGTGTATGTGTGTGTTTGTGACAGATTTGATCCCTGTTCTCTCTGCTGGCTCTATCTTGACCTGTGAAACGTATATTTAACT
AATTAAATATTAGTTAATATTAATAAATTTTAAGCTTTATCCAGACTGCAGGACAAGTTCGAGCATCTTAAAATGATTCAACAGGAGGAG
ATAAGGAAGCTCGAGGAAGAGAAAAAACAACTGGAAGGAGAAATCATAGATTTTTATAAAATGAAAGCTGCCTCCGAAGCACTGCAGACT
CAGCTGAGCACCGATACAAAGAAAGACAAACATCGTAAGAAATAATAGTTTCTCTTACTATTCTGAGAGCCCTATCATTCTACATCGCAA
CTTCCTGTGAGATTGTCTTTGTAGCATTTAACTCTGAAGTTCTCATTTTAAAAATTGGCTTGCTTATTGTATATTTTCCCCAACTAAAGT
GTGAACTCCTAGCGGGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGTGGACCACCTGAGGTCAGGAGTTC
AAAACCAGCCTGACCAAAATGATGAAACCCTGCCTCTACTAAAAATACAAAAATTAGCTGGGTTTGGTGGCCGGTACCTGTAATCCCAGC
CACTTGGGAGGCTGAGGCAGGAGAATCACTTGAACCCCGGAGGTGGAGGTTGCAGTGAGCCAAGATCTCACCATTGTACTCCAGCCTGGG
TGACAAGAGCAAAACTCCGCCTCAAAAAAAAAAAAAAAAAAAAAAGTATGAACTCCCAGAAGGCAGATCCTGTGTCCCTCTTTTCAGATT
CTGTATCTTGGCACTTAGGACGTACACTAACACAAATATGACTTTCAATCAATATTTGCCAAAATGAAAAAACAAAAGAAACACGTAGCA
TCATGTAAAAGGAGCTGGTTAGGTGGAGAAATTTATTTACCATAGTCCTGCTTTTGGATCCAGTAGTGACTTTTAACTTTTATATCCAAA
TAGAAGCTGGAGGCTTTGTTGGGGACTCATAGGCATAAAATGTTAAGTTATACAAATCTAATTAATAGGCCTATTTTCCTTTTTAAGTTC
TACTACTGATAATTTCTTGACAGTTTTTATGATAAAAGGTTGGAATTTGATAAGAACTCCCATGCTTTTGTGTCAGACTTAAAACTGATA
TTAGAATAAAGAATTCAAAAGCTAGAGAAAGAGTTGCATTTGAATGATAATATTATGTGTTACAGATTTGGGGTATATGCCAAAGTTATC
AAAGTTGTAGAAAATAAGGCCAGGTGTGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGCGGATCACTTGCGGTCA
GGAGCTTGAGAACAGCCCGGCCAACATGACGAAACCCCATCTCTACTAATAATACAAAAGTTAGCCGGGTGTGGTGTTGTGCACCTGTAG
TCCCTGCTACTCGGAAAGCTGAGGCAGGAGAATCGCTTGTAGCCAGGAGGCAGAGGTTGTAGTGAGCAGAGATTGCGCCACTGCACTCCA
GCCTGGGTGACAGAGCGCTGAGTCACCACACCTGGTATAAGCCACTGTGCCTGACCCACAATGACTTTTATACATATTGTTAAATCATCT
TACAGATTTTATAATTTGGGGGAAGAAAAATTTTACTAAATGATCTTTTAATGGAAACTCTACAAGAACCAGAATCTTTGCTTTGTTCAC
TTATGTATCCATTCCTAGGCCTAGAAAAATGTCTGACGCATAGCAGCAATTATTCATTGAATAAATGGACCCAGCAATAGTACATTAGCT
ATGCCATATGCATACATTAAAAATGTAGATTATTGACTTTCAAAAGATAATTAATGTAACTTCTTACTGCTTCTGAACATGTTTGTGAGT
TATATTGCTGAGGGACCTTTATCTTCTCATTCTTTCATCTTAATCCAATGTTATTAAAACTGAAACTGAAATCACCAATATTATTCCATA
TTTAAAAATAACATCTACCTTATAAAAATTATCATTGTGCTGCATTTGAGAATAGACTTTTTAGGTAATAATGGTATAATCCATAGGGTT
TTTGAGGGCACAGAAGGATTCATGCTAACAGAACATTTTATTTTCTATTTTCCAAGAGCTATAAAACATGATATTATATGATACTATAAG
GCATATTTTTATTTTCCATAATTTTTTCTAAAAAAAATTAGTGTTGGTTTTCCATATAACTTTTAACTTTATAAGTAAATATTTGTCTCT
TTCAGCTCCAGTTTCATGTGAAATAGAGTTTCCAGATTTATGTAGCATGGAAAGTTTTAATACGTCAGTTACTGATTTTTGCCAGTCATT
TTCTCAATTATTTACTTCTTTTATCTTTAGTTGATTTTTTTTGTAGTGACAAGTTTTGTTTCTATTCTCATTTCCTTTTGTGTATATTCT
ATGTAGATTTCGTTTTTGGTTACTATGAAAATTACATATAACATCCTGGAGTTATAACATTCTGATTTGAATTTATTTCAACTTAACTTC
AATCACATACCAAAATTCTACTGCTATATAGGTCTACTCTTTTTAGGTTATTGATGTAACAAATTGTATCTTTATTCATTGTACACCACC

>25482_25482_10_EGFR-SEPT14_EGFR_chr7_55270318_ENST00000455089_SEPT14_chr7_55863785_ENST00000388975_length(amino acids)=1064AA_BP=
MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVL
IALNTVERIPLENLQIIRGNMYYENSYALAVLSNYDANKTGLKELPMRNLQGQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRG
KSPSDCCHNQCAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGADS
YEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFL
LIQAWPENRTDLHAFENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKLFGTSGQKTKIISNRG
ENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHY
IDGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGIGLFMRRRHIVR
KRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYV
MASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITD
FGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYM
IMVKCWMIDADSRPKFRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQQGFFSSPSTSRTPLL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for EGFR-SEPT14


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for EGFR-SEPT14


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for EGFR-SEPT14


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource