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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:EHBP1-BCL11A (FusionGDB2 ID:25525)

Fusion Gene Summary for EHBP1-BCL11A

check button Fusion gene summary
Fusion gene informationFusion gene name: EHBP1-BCL11A
Fusion gene ID: 25525
HgeneTgene
Gene symbol

EHBP1

BCL11A

Gene ID

23301

53335

Gene nameEH domain binding protein 1BAF chromatin remodeling complex subunit BCL11A
SynonymsHPC12|NACSINBCL11A-L|BCL11A-S|BCL11A-XL|BCL11a-M|CTIP1|DILOS|EVI9|HBFQTL5|ZNF856
Cytomap

2p15

2p16.1

Type of geneprotein-codingprotein-coding
DescriptionEH domain-binding protein 1NPF calponin-like proteintestis tissue sperm-binding protein Li 50eB-cell lymphoma/leukemia 11AB cell CLL/lymphoma 11AB-cell CLL/lymphoma 11A (zinc finger protein) isoform 2BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1BCL11A, BAF complex componentC2H2-type zinc finger proteinCOUP-TF-interacting pro
Modification date2020031320200313
UniProtAcc

Q8NDI1

Q9H165

Ensembl transtripts involved in fusion geneENST00000263991, ENST00000354487, 
ENST00000405015, ENST00000405289, 
ENST00000431489, ENST00000496857, 
ENST00000335712, ENST00000358510, 
ENST00000477659, ENST00000356842, 
ENST00000359629, ENST00000538214, 
ENST00000537768, 
Fusion gene scores* DoF score8 X 12 X 8=76810 X 9 X 3=270
# samples 209
** MAII scorelog2(20/768*10)=-1.94110631094643
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/270*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EHBP1 [Title/Abstract] AND BCL11A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEHBP1(63101667)-BCL11A(60679801), # samples:3
Anticipated loss of major functional domain due to fusion event.EHBP1-BCL11A seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
EHBP1-BCL11A seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
EHBP1-BCL11A seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneBCL11A

GO:0000122

negative regulation of transcription by RNA polymerase II

19153051


check buttonFusion gene breakpoints across EHBP1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across BCL11A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-D8-A147-01AEHBP1chr2

63101667

-BCL11Achr2

60679801

-
ChimerDB4BRCATCGA-D8-A147-01AEHBP1chr2

63101667

+BCL11Achr2

60679801

-


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Fusion Gene ORF analysis for EHBP1-BCL11A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000263991ENST00000335712EHBP1chr2

63101667

+BCL11Achr2

60679801

-
5CDS-intronENST00000263991ENST00000358510EHBP1chr2

63101667

+BCL11Achr2

60679801

-
5CDS-intronENST00000263991ENST00000477659EHBP1chr2

63101667

+BCL11Achr2

60679801

-
5CDS-intronENST00000354487ENST00000335712EHBP1chr2

63101667

+BCL11Achr2

60679801

-
5CDS-intronENST00000354487ENST00000358510EHBP1chr2

63101667

+BCL11Achr2

60679801

-
5CDS-intronENST00000354487ENST00000477659EHBP1chr2

63101667

+BCL11Achr2

60679801

-
5CDS-intronENST00000405015ENST00000335712EHBP1chr2

63101667

+BCL11Achr2

60679801

-
5CDS-intronENST00000405015ENST00000358510EHBP1chr2

63101667

+BCL11Achr2

60679801

-
5CDS-intronENST00000405015ENST00000477659EHBP1chr2

63101667

+BCL11Achr2

60679801

-
5CDS-intronENST00000405289ENST00000335712EHBP1chr2

63101667

+BCL11Achr2

60679801

-
5CDS-intronENST00000405289ENST00000358510EHBP1chr2

63101667

+BCL11Achr2

60679801

-
5CDS-intronENST00000405289ENST00000477659EHBP1chr2

63101667

+BCL11Achr2

60679801

-
5CDS-intronENST00000431489ENST00000335712EHBP1chr2

63101667

+BCL11Achr2

60679801

-
5CDS-intronENST00000431489ENST00000358510EHBP1chr2

63101667

+BCL11Achr2

60679801

-
5CDS-intronENST00000431489ENST00000477659EHBP1chr2

63101667

+BCL11Achr2

60679801

-
Frame-shiftENST00000263991ENST00000356842EHBP1chr2

63101667

+BCL11Achr2

60679801

-
Frame-shiftENST00000263991ENST00000359629EHBP1chr2

63101667

+BCL11Achr2

60679801

-
Frame-shiftENST00000263991ENST00000538214EHBP1chr2

63101667

+BCL11Achr2

60679801

-
Frame-shiftENST00000354487ENST00000356842EHBP1chr2

63101667

+BCL11Achr2

60679801

-
Frame-shiftENST00000354487ENST00000359629EHBP1chr2

63101667

+BCL11Achr2

60679801

-
Frame-shiftENST00000354487ENST00000538214EHBP1chr2

63101667

+BCL11Achr2

60679801

-
Frame-shiftENST00000405015ENST00000356842EHBP1chr2

63101667

+BCL11Achr2

60679801

-
Frame-shiftENST00000405015ENST00000359629EHBP1chr2

63101667

+BCL11Achr2

60679801

-
Frame-shiftENST00000405015ENST00000538214EHBP1chr2

63101667

+BCL11Achr2

60679801

-
Frame-shiftENST00000405289ENST00000356842EHBP1chr2

63101667

+BCL11Achr2

60679801

-
Frame-shiftENST00000405289ENST00000359629EHBP1chr2

63101667

+BCL11Achr2

60679801

-
Frame-shiftENST00000405289ENST00000538214EHBP1chr2

63101667

+BCL11Achr2

60679801

-
Frame-shiftENST00000431489ENST00000356842EHBP1chr2

63101667

+BCL11Achr2

60679801

-
Frame-shiftENST00000431489ENST00000359629EHBP1chr2

63101667

+BCL11Achr2

60679801

-
Frame-shiftENST00000431489ENST00000538214EHBP1chr2

63101667

+BCL11Achr2

60679801

-
In-frameENST00000263991ENST00000537768EHBP1chr2

63101667

+BCL11Achr2

60679801

-
In-frameENST00000354487ENST00000537768EHBP1chr2

63101667

+BCL11Achr2

60679801

-
In-frameENST00000405015ENST00000537768EHBP1chr2

63101667

+BCL11Achr2

60679801

-
In-frameENST00000405289ENST00000537768EHBP1chr2

63101667

+BCL11Achr2

60679801

-
In-frameENST00000431489ENST00000537768EHBP1chr2

63101667

+BCL11Achr2

60679801

-
intron-3CDSENST00000496857ENST00000356842EHBP1chr2

63101667

+BCL11Achr2

60679801

-
intron-3CDSENST00000496857ENST00000359629EHBP1chr2

63101667

+BCL11Achr2

60679801

-
intron-3CDSENST00000496857ENST00000537768EHBP1chr2

63101667

+BCL11Achr2

60679801

-
intron-3CDSENST00000496857ENST00000538214EHBP1chr2

63101667

+BCL11Achr2

60679801

-
intron-intronENST00000496857ENST00000335712EHBP1chr2

63101667

+BCL11Achr2

60679801

-
intron-intronENST00000496857ENST00000358510EHBP1chr2

63101667

+BCL11Achr2

60679801

-
intron-intronENST00000496857ENST00000477659EHBP1chr2

63101667

+BCL11Achr2

60679801

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000405015EHBP1chr263101667+ENST00000537768BCL11Achr260679801-188017135191814431
ENST00000431489EHBP1chr263101667+ENST00000537768BCL11Achr260679801-195817915971892431
ENST00000354487EHBP1chr263101667+ENST00000537768BCL11Achr260679801-183416674731768431
ENST00000263991EHBP1chr263101667+ENST00000537768BCL11Achr260679801-193917724731873466
ENST00000405289EHBP1chr263101667+ENST00000537768BCL11Achr260679801-1352118501286428

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000405015ENST00000537768EHBP1chr263101667+BCL11Achr260679801-0.001428610.9985714
ENST00000431489ENST00000537768EHBP1chr263101667+BCL11Achr260679801-0.0013986180.9986014
ENST00000354487ENST00000537768EHBP1chr263101667+BCL11Achr260679801-0.0013739420.9986261
ENST00000263991ENST00000537768EHBP1chr263101667+BCL11Achr260679801-0.0012681790.9987318
ENST00000405289ENST00000537768EHBP1chr263101667+BCL11Achr260679801-0.0025519050.9974481

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Fusion Genomic Features for EHBP1-BCL11A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for EHBP1-BCL11A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:63101667/chr2:60679801)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
EHBP1

Q8NDI1

BCL11A

Q9H165

FUNCTION: May play a role in actin reorganization. Links clathrin-mediated endocytosis to the actin cytoskeleton. May act as Rab effector protein and play a role in vesicle trafficking (PubMed:14676205, PubMed:27552051). Required for perinuclear sorting and insulin-regulated recycling of SLC2A4/GLUT4 in adipocytes (By similarity). {ECO:0000250|UniProtKB:Q69ZW3, ECO:0000269|PubMed:14676205, ECO:0000305|PubMed:27552051}.FUNCTION: Transcription factor associated with the BAF SWI/SNF chromatin remodeling complex (By similarity). Repressor of fetal hemoglobin (HbF) level (PubMed:26375765). Involved in brain development (PubMed:27453576). May play a role in hematopoiesis. Essential factor in lymphopoiesis required for B-cell formation in fetal liver. May function as a modulator of the transcriptional repression activity of ARP1 (By similarity). {ECO:0000250|UniProtKB:Q9QYE3, ECO:0000303|PubMed:26375765, ECO:0000303|PubMed:27453576}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEHBP1chr2:63101667chr2:60679801ENST00000263991+1125185_2104301232.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000354487+1024185_2103951197.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405015+1023185_2103951161.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405289+923185_2103951197.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000431489+1023185_2103951161.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000263991+1125362_3654301232.0Compositional biasNote=Poly-Glu
HgeneEHBP1chr2:63101667chr2:60679801ENST00000354487+1024362_3653951197.0Compositional biasNote=Poly-Glu
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405015+1023362_3653951161.0Compositional biasNote=Poly-Glu
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405289+923362_3653951197.0Compositional biasNote=Poly-Glu
HgeneEHBP1chr2:63101667chr2:60679801ENST00000431489+1023362_3653951161.0Compositional biasNote=Poly-Glu
HgeneEHBP1chr2:63101667chr2:60679801ENST00000263991+11258_1584301232.0DomainC2 NT-type
HgeneEHBP1chr2:63101667chr2:60679801ENST00000354487+10248_1583951197.0DomainC2 NT-type
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405015+10238_1583951161.0DomainC2 NT-type
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405289+9238_1583951197.0DomainC2 NT-type
HgeneEHBP1chr2:63101667chr2:60679801ENST00000431489+10238_1583951161.0DomainC2 NT-type
TgeneBCL11Achr2:63101667chr2:60679801ENST0000033571204260_3730836.0Compositional biasNote=Pro-rich
TgeneBCL11Achr2:63101667chr2:60679801ENST0000033571204481_5090836.0Compositional biasNote=Glu-rich
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035851003260_3730802.0Compositional biasNote=Pro-rich
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035851003481_5090802.0Compositional biasNote=Glu-rich
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035962935260_373210244.0Compositional biasNote=Pro-rich
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035962935481_509210244.0Compositional biasNote=Glu-rich
TgeneBCL11Achr2:63101667chr2:60679801ENST00000335712041_2100836.0RegionRequired for nuclear body formation and for SUMO1 recruitment
TgeneBCL11Achr2:63101667chr2:60679801ENST00000358510031_2100802.0RegionRequired for nuclear body formation and for SUMO1 recruitment
TgeneBCL11Achr2:63101667chr2:60679801ENST0000033571204170_1930836.0Zinc fingerC2H2-type 1
TgeneBCL11Achr2:63101667chr2:60679801ENST0000033571204377_3990836.0Zinc fingerC2H2-type 2
TgeneBCL11Achr2:63101667chr2:60679801ENST0000033571204405_4290836.0Zinc fingerC2H2-type 3
TgeneBCL11Achr2:63101667chr2:60679801ENST0000033571204742_7640836.0Zinc fingerC2H2-type 4
TgeneBCL11Achr2:63101667chr2:60679801ENST0000033571204770_7920836.0Zinc fingerC2H2-type 5
TgeneBCL11Achr2:63101667chr2:60679801ENST0000033571204800_8230836.0Zinc fingerC2H2-type 6
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035684235742_764743774.0Zinc fingerC2H2-type 4
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035684235770_792743774.0Zinc fingerC2H2-type 5
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035684235800_823743774.0Zinc fingerC2H2-type 6
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035851003170_1930802.0Zinc fingerC2H2-type 1
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035851003377_3990802.0Zinc fingerC2H2-type 2
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035851003405_4290802.0Zinc fingerC2H2-type 3
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035851003742_7640802.0Zinc fingerC2H2-type 4
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035851003770_7920802.0Zinc fingerC2H2-type 5
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035851003800_8230802.0Zinc fingerC2H2-type 6
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035962935377_399210244.0Zinc fingerC2H2-type 2
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035962935405_429210244.0Zinc fingerC2H2-type 3
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035962935742_764210244.0Zinc fingerC2H2-type 4
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035962935770_792210244.0Zinc fingerC2H2-type 5
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035962935800_823210244.0Zinc fingerC2H2-type 6

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEHBP1chr2:63101667chr2:60679801ENST00000263991+11251076_11004301232.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000263991+11251136_12304301232.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000263991+1125808_8794301232.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000354487+10241076_11003951197.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000354487+10241136_12303951197.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000354487+1024808_8793951197.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405015+10231076_11003951161.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405015+10231136_12303951161.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405015+1023808_8793951161.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405289+9231076_11003951197.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405289+9231136_12303951197.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405289+923808_8793951197.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000431489+10231076_11003951161.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000431489+10231136_12303951161.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000431489+1023808_8793951161.0Coiled coilOntology_term=ECO:0000255
HgeneEHBP1chr2:63101667chr2:60679801ENST00000263991+11251110_11134301232.0Compositional biasNote=Poly-Glu
HgeneEHBP1chr2:63101667chr2:60679801ENST00000354487+10241110_11133951197.0Compositional biasNote=Poly-Glu
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405015+10231110_11133951161.0Compositional biasNote=Poly-Glu
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405289+9231110_11133951197.0Compositional biasNote=Poly-Glu
HgeneEHBP1chr2:63101667chr2:60679801ENST00000431489+10231110_11133951161.0Compositional biasNote=Poly-Glu
HgeneEHBP1chr2:63101667chr2:60679801ENST00000263991+11251056_12124301232.0DomainbMERB
HgeneEHBP1chr2:63101667chr2:60679801ENST00000263991+1125443_5484301232.0DomainCalponin-homology (CH)
HgeneEHBP1chr2:63101667chr2:60679801ENST00000354487+10241056_12123951197.0DomainbMERB
HgeneEHBP1chr2:63101667chr2:60679801ENST00000354487+1024443_5483951197.0DomainCalponin-homology (CH)
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405015+10231056_12123951161.0DomainbMERB
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405015+1023443_5483951161.0DomainCalponin-homology (CH)
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405289+9231056_12123951197.0DomainbMERB
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405289+923443_5483951197.0DomainCalponin-homology (CH)
HgeneEHBP1chr2:63101667chr2:60679801ENST00000431489+10231056_12123951161.0DomainbMERB
HgeneEHBP1chr2:63101667chr2:60679801ENST00000431489+1023443_5483951161.0DomainCalponin-homology (CH)
HgeneEHBP1chr2:63101667chr2:60679801ENST00000263991+11251228_12314301232.0MotifCAAX motif
HgeneEHBP1chr2:63101667chr2:60679801ENST00000354487+10241228_12313951197.0MotifCAAX motif
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405015+10231228_12313951161.0MotifCAAX motif
HgeneEHBP1chr2:63101667chr2:60679801ENST00000405289+9231228_12313951197.0MotifCAAX motif
HgeneEHBP1chr2:63101667chr2:60679801ENST00000431489+10231228_12313951161.0MotifCAAX motif
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035684235260_373743774.0Compositional biasNote=Pro-rich
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035684235481_509743774.0Compositional biasNote=Glu-rich
TgeneBCL11Achr2:63101667chr2:60679801ENST00000356842351_210743774.0RegionRequired for nuclear body formation and for SUMO1 recruitment
TgeneBCL11Achr2:63101667chr2:60679801ENST00000359629351_210210244.0RegionRequired for nuclear body formation and for SUMO1 recruitment
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035684235170_193743774.0Zinc fingerC2H2-type 1
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035684235377_399743774.0Zinc fingerC2H2-type 2
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035684235405_429743774.0Zinc fingerC2H2-type 3
TgeneBCL11Achr2:63101667chr2:60679801ENST0000035962935170_193210244.0Zinc fingerC2H2-type 1


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Fusion Gene Sequence for EHBP1-BCL11A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>25525_25525_1_EHBP1-BCL11A_EHBP1_chr2_63101667_ENST00000263991_BCL11A_chr2_60679801_ENST00000537768_length(transcript)=1939nt_BP=1772nt
GGGCGCCGTCCGCCTGAGGGGCTGCAGATCCCGGCTACCGCGAGCGCCGTGGCTGGCTTGGCTGTTCCATGTGGCTCCGGCGGGGATGGA
GGACTCGGTGGCGGCGGCGGCTGCTGCTGCGGCGGCGACGGAGGAGCGGCTATGAGAAGGGAACGGGGCCAGACTCAGCCCGACAGCGGG
ATTAGAGCCCTCCAGAATACCCATCATATAGCCCCTGAGGTGGCATGGTGATGTCTCCATGAGGGAACCCCTTCCCACTCATCCTGTCAC
GTATATCATAGTGTTCTTGACTGGGCCATTCATCTAAGATGGGATTTACCCTGTGAAACAGGGAGAAGACTTATGGACCCCAAGCATCAT
TTCGAGTTGTAGTTGAGTTTTTAAAAGACATACATGCAAAGTTCCTTTGCTTTGGACCCTCTGCATTATTAAAGCTGCTGTATTGCTAAC
CCAGAACTGCTCCAGTGTCTTGACTGATCATCATGGCTTCAGTTTGGAAGAGACTGCAGCGTGTGGGAAAACATGCATCCAAGTTCCAGT
TTGTGGCCTCCTACCAGGAGCTCATGGTTGAGTGTACGAAGAAATGGCAACCAGATAAACTGGTGGTAGTTTGGACCAGAAGAAGCCGAA
GGAAGTCTTCTAAGGCACATAGCTGGCAACCTGGAATAAAAAATCCCTATCGTGGTGTTGTTGTGTGGCCTGTTCCTGAAAACATTGAAA
TCACTGTAACACTTTTTAAGGATCCTCATGCGGAAGAATTTGAAGACAAAGAGTGGACATTTGTCATAGAAAATGAATCCCCTTCTGGTC
GAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGC
CATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGC
AAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACA
GAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAAATTGTAAACCAGTTGAATGCTCTGAGCAGCTTAGATGAAGATCAAGATGACT
GCATAAAGCAAGCAAATATGCGTTCAGCTAAATCAGCCAGTTCCTCTGAAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAA
AGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTA
TCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATT
TGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATA
TGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTC
CTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAA
AAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGGTTCTTCACACACCCCCATTCGGCGTAG
TACCCAGAGAGCTCAAGATGTGTGGCAGTTTTCGGATGGAAGCTCGAGAGCCCTTAAGTTCTGAGAAAATTTGAAGCCCCCAGGGGTGGG

>25525_25525_1_EHBP1-BCL11A_EHBP1_chr2_63101667_ENST00000263991_BCL11A_chr2_60679801_ENST00000537768_length(amino acids)=466AA_BP=429
MIIMASVWKRLQRVGKHASKFQFVASYQELMVECTKKWQPDKLVVVWTRRSRRKSSKAHSWQPGIKNPYRGVVVWPVPENIEITVTLFKD
PHAEEFEDKEWTFVIENESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMS
MKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITEIVNQLNALSSLDEDQDDCIKQANMRSAKSASSSEELINKLNFLDEAEKDLATVNS
NPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYAD
SSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETERRVKRKAPAPPVLSPKTGVLNENTVSAGKDLSTSPKVLHTPPFGVVPRELKMC

--------------------------------------------------------------
>25525_25525_2_EHBP1-BCL11A_EHBP1_chr2_63101667_ENST00000354487_BCL11A_chr2_60679801_ENST00000537768_length(transcript)=1834nt_BP=1667nt
GGGCGCCGTCCGCCTGAGGGGCTGCAGATCCCGGCTACCGCGAGCGCCGTGGCTGGCTTGGCTGTTCCATGTGGCTCCGGCGGGGATGGA
GGACTCGGTGGCGGCGGCGGCTGCTGCTGCGGCGGCGACGGAGGAGCGGCTATGAGAAGGGAACGGGGCCAGACTCAGCCCGACAGCGGG
ATTAGAGCCCTCCAGAATACCCATCATATAGCCCCTGAGGTGGCATGGTGATGTCTCCATGAGGGAACCCCTTCCCACTCATCCTGTCAC
GTATATCATAGTGTTCTTGACTGGGCCATTCATCTAAGATGGGATTTACCCTGTGAAACAGGGAGAAGACTTATGGACCCCAAGCATCAT
TTCGAGTTGTAGTTGAGTTTTTAAAAGACATACATGCAAAGTTCCTTTGCTTTGGACCCTCTGCATTATTAAAGCTGCTGTATTGCTAAC
CCAGAACTGCTCCAGTGTCTTGACTGATCATCATGGCTTCAGTTTGGAAGAGACTGCAGCGTGTGGGAAAACATGCATCCAAGTTCCAGT
TTGTGGCCTCCTACCAGGAGCTCATGGTTGAGTGTACGAAGAAATGGCAACCAGATAAACTGGTGGTAGTTTGGACCAGAAGAAGCCGAA
GGAAGTCTTCTAAGGCACATAGCTGGCAACCTGGAATAAAAAATCCCTATCGTGGTGTTGTTGTGTGGCCTGTTCCTGAAAACATTGAAA
TCACTGTAACACTTTTTAAGGATCCTCATGCGGAAGAATTTGAAGACAAAGAGTGGACATTTGTCATAGAAAATGAATCCCCTTCTGGTC
GAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGC
CATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGC
AAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACA
GAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCG
TGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTT
CACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATG
AGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCT
ATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGG
TAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAA
ATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGGTTCTTCACACACCCCCATTCGGCGTAGTACCCAGAGAGCTCA
AGATGTGTGGCAGTTTTCGGATGGAAGCTCGAGAGCCCTTAAGTTCTGAGAAAATTTGAAGCCCCCAGGGGTGGGGTGGACGCGTGCCGC

>25525_25525_2_EHBP1-BCL11A_EHBP1_chr2_63101667_ENST00000354487_BCL11A_chr2_60679801_ENST00000537768_length(amino acids)=431AA_BP=394
MIIMASVWKRLQRVGKHASKFQFVASYQELMVECTKKWQPDKLVVVWTRRSRRKSSKAHSWQPGIKNPYRGVVVWPVPENIEITVTLFKD
PHAEEFEDKEWTFVIENESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMS
MKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDS
FYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELE

--------------------------------------------------------------
>25525_25525_3_EHBP1-BCL11A_EHBP1_chr2_63101667_ENST00000405015_BCL11A_chr2_60679801_ENST00000537768_length(transcript)=1880nt_BP=1713nt
AACTGGGAGGCTCCCCAGTTTGTGGGTAACATCTGACTCTCCCTCCCCAAAGAGAGACTCCAGCGAGAGACTGGGGATTTGGAGGTCCAA
GTCATGGCAGAACTGGGTTGCTTGCTAGGACACAAGGTTAGCATGCCCCTGTAGCAGCAATGTGAGAATCAGAAAAGGTGACTGTGCATC
TCAAGAAGCCGAATCAAAAAGCCAAGCCAACCACCTAACCAGTGATTTTCAAGCCCTCCAGAATACCCATCATATAGCCCCTGAGGTGGC
ATGGTGATGTCTCCATGAGGGAACCCCTTCCCACTCATCCTGTCACGTATATCATAGTGTTCTTGACTGGGCCATTCATCTAAGATGGGA
TTTACCCTGTGAAACAGGGAGAAGACTTATGGACCCCAAGCATCATTTCGAGTTGTAGTTGAGTTTTTAAAAGACATACATGCAAAGTTC
CTTTGCTTTGGACCCTCTGCATTATTAAAGCTGCTGTATTGCTAACCCAGAACTGCTCCAGTGTCTTGACTGATCATCATGGCTTCAGTT
TGGAAGAGACTGCAGCGTGTGGGAAAACATGCATCCAAGTTCCAGTTTGTGGCCTCCTACCAGGAGCTCATGGTTGAGTGTACGAAGAAA
TGGCAACCAGATAAACTGGTGGTAGTTTGGACCAGAAGAAGCCGAAGGAAGTCTTCTAAGGCACATAGCTGGCAACCTGGAATAAAAAAT
CCCTATCGTGGTGTTGTTGTGTGGCCTGTTCCTGAAAACATTGAAATCACTGTAACACTTTTTAAGGATCCTCATGCGGAAGAATTTGAA
GACAAAGAGTGGACATTTGTCATAGAAAATGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTAT
GCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTA
TCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGC
AATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATC
AACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAAT
CCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAAT
CCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCT
ACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCA
AATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGA
AAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCT
AAGGTTCTTCACACACCCCCATTCGGCGTAGTACCCAGAGAGCTCAAGATGTGTGGCAGTTTTCGGATGGAAGCTCGAGAGCCCTTAAGT

>25525_25525_3_EHBP1-BCL11A_EHBP1_chr2_63101667_ENST00000405015_BCL11A_chr2_60679801_ENST00000537768_length(amino acids)=431AA_BP=394
MIIMASVWKRLQRVGKHASKFQFVASYQELMVECTKKWQPDKLVVVWTRRSRRKSSKAHSWQPGIKNPYRGVVVWPVPENIEITVTLFKD
PHAEEFEDKEWTFVIENESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMS
MKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDS
FYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELE

--------------------------------------------------------------
>25525_25525_4_EHBP1-BCL11A_EHBP1_chr2_63101667_ENST00000405289_BCL11A_chr2_60679801_ENST00000537768_length(transcript)=1352nt_BP=1185nt
ATGGCTTCAGTTTGGAAGAGACTGCAGCGTGTGGGAAAACATGCATCCAAGTTCCAGTTTGTGGCCTCCTACCAGGAGCTCATGGTTGAG
TGTACGAAGAAATGGCAACCAGATAAACTGGTGGTAGTTTGGACCAGAAGAAGCCGAAGGAAGTCTTCTAAGGCACATAGCTGGCAACCT
GGAATAAAAAATCCCTATCGTGGTGTTGTTGTGTGGCCTGTTCCTGAAAACATTGAAATCACTGTAACACTTTTTAAGGATCCTCATGCG
GAAGAATTTGAAGACAAAGAGTGGACATTTGTCATAGAAAATGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAAT
ATGAAACAGTATGCAAGCCCTATGCCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTT
CAGTTTTCATTATCTTGCATTTTTCTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAG
GCTGACATTGGCAATTTAGATGACTTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATT
ACAGAGCTTATCAACAAACTTAACTTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCT
GCAGAATTAAATCCATTTGGAGATCCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAAT
AACAGCTATAATCCCTTTAAAGAGGTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCT
CCTCCCCAGTCTACAAAAAGAAAAAATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAA
TTGGATGAATCAAATCCTTTTTATGAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGG
CGAGTGAAAAGAAAGGCCCCGGCTCCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTC
TCTACTTCTCCTAAGGTTCTTCACACACCCCCATTCGGCGTAGTACCCAGAGAGCTCAAGATGTGTGGCAGTTTTCGGATGGAAGCTCGA
GAGCCCTTAAGTTCTGAGAAAATTTGAAGCCCCCAGGGGTGGGGTGGACGCGTGCCGCCCAGTCGACGTCAGCGTGGTCTGTCATCCTGC

>25525_25525_4_EHBP1-BCL11A_EHBP1_chr2_63101667_ENST00000405289_BCL11A_chr2_60679801_ENST00000537768_length(amino acids)=428AA_BP=391
MASVWKRLQRVGKHASKFQFVASYQELMVECTKKWQPDKLVVVWTRRSRRKSSKAHSWQPGIKNPYRGVVVWPVPENIEITVTLFKDPHA
EEFEDKEWTFVIENESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMSMKQ
ADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDSFYN
NSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELETER

--------------------------------------------------------------
>25525_25525_5_EHBP1-BCL11A_EHBP1_chr2_63101667_ENST00000431489_BCL11A_chr2_60679801_ENST00000537768_length(transcript)=1958nt_BP=1791nt
GATGATGGTGGCGGAGGAGAAAGGCGGGGGAGGGGGTGCTGGGCGCTGAGCGGTGGCTCTGGCAGGGCTTGGTAGGGTGGGGGACGGTCG
CGGGGCGATCTGTCAGGGAGGGGGTGGGCGTGAGGGGCGCCGTCCGCCTGAGGGGCTGCAGATCCCGGCTACCGCGAGCGCCGTGGCTGG
CTTGGCTGTTCCATGTGGCTCCGGCGGGGATGGAGGACTCGGTGGCGGCGGCGGCTGCTGCTGCGGCGGCGACGGAGGAGCGGCTATGAG
AAGGGAACGGGGCCAGACTCAGCCCGACAGCGGGATTAGAGCCCTCCAGAATACCCATCATATAGCCCCTGAGGTGGCATGGTGATGTCT
CCATGAGGGAACCCCTTCCCACTCATCCTGTCACGTATATCATAGTGTTCTTGACTGGGCCATTCATCTAAGATGGGATTTACCCTGTGA
AACAGGGAGAAGACTTATGGACCCCAAGCATCATTTCGAGTTGTAGTTGAGTTTTTAAAAGACATACATGCAAAGTTCCTTTGCTTTGGA
CCCTCTGCATTATTAAAGCTGCTGTATTGCTAACCCAGAACTGCTCCAGTGTCTTGACTGATCATCATGGCTTCAGTTTGGAAGAGACTG
CAGCGTGTGGGAAAACATGCATCCAAGTTCCAGTTTGTGGCCTCCTACCAGGAGCTCATGGTTGAGTGTACGAAGAAATGGCAACCAGAT
AAACTGGTGGTAGTTTGGACCAGAAGAAGCCGAAGGAAGTCTTCTAAGGCACATAGCTGGCAACCTGGAATAAAAAATCCCTATCGTGGT
GTTGTTGTGTGGCCTGTTCCTGAAAACATTGAAATCACTGTAACACTTTTTAAGGATCCTCATGCGGAAGAATTTGAAGACAAAGAGTGG
ACATTTGTCATAGAAAATGAATCCCCTTCTGGTCGAAGGAAAGCTCTTGCTACTAGCAGCATCAATATGAAACAGTATGCAAGCCCTATG
CCAACTCAGACTGATGTCAAGTTAAAATTCAAGCCATTATCTAAAAAAGTTGTATCTGCCGCTCTTCAGTTTTCATTATCTTGCATTTTT
CTGAGGGAAGGAAAAGCCACAGATGAAGACATGCAAAGTTTGGCTAGTTTGATGAGTATGAAGCAGGCTGACATTGGCAATTTAGATGAC
TTCGAAGAAGATAATGAAGATGATGATGAGAACAGAGTGAACCAAGAAGAAAAGGCAGCTAAAATTACAGAGCTTATCAACAAACTTAAC
TTTTTGGATGAAGCAGAAAAGGACTTGGCCACCGTGAATTCAAATCCATTTGATGATCCTGATGCTGCAGAATTAAATCCATTTGGAGAT
CCTGACTCAGAAGAACCTATCACTGAAACAGCTTCACCTAGAAAAACAGAAGACTCTTTTTATAATAACAGCTATAATCCCTTTAAAGAG
GTGCAGACTCCACAGTATTTGAACCCATTCGATGAGCCAGAAGCATTTGTGACCATAAAGGATTCTCCTCCCCAGTCTACAAAAAGAAAA
AATATAAGACCTGTGGATATGAGCAAGTACCTCTATGCTGATAGTTCTAAAACTGAAGAAGAAGAATTGGATGAATCAAATCCTTTTTAT
GAACCTAAATCAACTCCTCCTCCAAATAATTTGGTAAATCCTGTTCAAGAACTAGAAACTGAAAGGCGAGTGAAAAGAAAGGCCCCGGCT
CCACCAGTCCTCTCACCAAAAACAGGAGTATTAAATGAAAACACAGTTTCTGCAGGAAAAGATCTCTCTACTTCTCCTAAGGTTCTTCAC
ACACCCCCATTCGGCGTAGTACCCAGAGAGCTCAAGATGTGTGGCAGTTTTCGGATGGAAGCTCGAGAGCCCTTAAGTTCTGAGAAAATT

>25525_25525_5_EHBP1-BCL11A_EHBP1_chr2_63101667_ENST00000431489_BCL11A_chr2_60679801_ENST00000537768_length(amino acids)=431AA_BP=394
MIIMASVWKRLQRVGKHASKFQFVASYQELMVECTKKWQPDKLVVVWTRRSRRKSSKAHSWQPGIKNPYRGVVVWPVPENIEITVTLFKD
PHAEEFEDKEWTFVIENESPSGRRKALATSSINMKQYASPMPTQTDVKLKFKPLSKKVVSAALQFSLSCIFLREGKATDEDMQSLASLMS
MKQADIGNLDDFEEDNEDDDENRVNQEEKAAKITELINKLNFLDEAEKDLATVNSNPFDDPDAAELNPFGDPDSEEPITETASPRKTEDS
FYNNSYNPFKEVQTPQYLNPFDEPEAFVTIKDSPPQSTKRKNIRPVDMSKYLYADSSKTEEEELDESNPFYEPKSTPPPNNLVNPVQELE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for EHBP1-BCL11A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for EHBP1-BCL11A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for EHBP1-BCL11A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource