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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:EIF3K-PPP2R2A (FusionGDB2 ID:25888)

Fusion Gene Summary for EIF3K-PPP2R2A

check button Fusion gene summary
Fusion gene informationFusion gene name: EIF3K-PPP2R2A
Fusion gene ID: 25888
HgeneTgene
Gene symbol

EIF3K

PPP2R2A

Gene ID

27335

5520

Gene nameeukaryotic translation initiation factor 3 subunit Kprotein phosphatase 2 regulatory subunit Balpha
SynonymsARG134|EIF3-p28|EIF3S12|HSPC029|M9|MSTP001|PLAC-24|PLAC24|PRO1474|PTD001B55A|B55ALPHA|PR52A|PR55A|PR55alpha
Cytomap

19q13.2

8p21.2

Type of geneprotein-codingprotein-coding
Descriptioneukaryotic translation initiation factor 3 subunit KeIF-3 p28eukaryotic translation initiation factor 3, subunit 12muscle specificmuscle-specific gene M9 proteinserine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoformprotein phosphatase 2, regulatory subunit B, alpha
Modification date2020032220200327
UniProtAcc

Q9UBQ5

.
Ensembl transtripts involved in fusion geneENST00000593062, ENST00000248342, 
ENST00000538434, ENST00000545173, 
ENST00000588934, ENST00000592558, 
ENST00000593149, 		ENST00000315985, 
ENST00000380737, ENST00000523473, 
Fusion gene scores* DoF score9 X 9 X 4=3248 X 13 X 5=520
# samples 1213
** MAII scorelog2(12/324*10)=-1.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/520*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EIF3K [Title/Abstract] AND PPP2R2A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEIF3K(39116742)-PPP2R2A(26227650), # samples:3
Anticipated loss of major functional domain due to fusion event.EIF3K-PPP2R2A seems lost the major protein functional domain in Hgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
EIF3K-PPP2R2A seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
EIF3K-PPP2R2A seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
EIF3K-PPP2R2A seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneEIF3K

GO:0006413

translational initiation

17581632

TgenePPP2R2A

GO:0006470

protein dephosphorylation

1849734


check buttonFusion gene breakpoints across EIF3K (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PPP2R2A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-77-7338-01AEIF3Kchr19

39116742

-PPP2R2Achr8

26227650

+
ChimerDB4LUSCTCGA-77-7338-01AEIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
ChimerDB4LUSCTCGA-77-7338EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
ChimerDB4LUSCTCGA-77-7338EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
ChimerDB4LUSCTCGA-77-7338EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+


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Fusion Gene ORF analysis for EIF3K-PPP2R2A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000593062ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
3UTR-3CDSENST00000593062ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
3UTR-3CDSENST00000593062ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
3UTR-3CDSENST00000593062ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
3UTR-3CDSENST00000593062ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
3UTR-3CDSENST00000593062ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
3UTR-intronENST00000593062ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
3UTR-intronENST00000593062ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
3UTR-intronENST00000593062ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
5CDS-intronENST00000248342ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
5CDS-intronENST00000248342ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
5CDS-intronENST00000248342ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
5CDS-intronENST00000538434ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
5CDS-intronENST00000538434ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
5CDS-intronENST00000538434ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
5CDS-intronENST00000545173ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
5CDS-intronENST00000545173ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
5CDS-intronENST00000545173ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
5CDS-intronENST00000588934ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
5CDS-intronENST00000588934ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
5CDS-intronENST00000588934ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
5CDS-intronENST00000592558ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
5CDS-intronENST00000592558ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
5CDS-intronENST00000592558ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
5CDS-intronENST00000593149ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
5CDS-intronENST00000593149ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
5CDS-intronENST00000593149ENST00000523473EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
Frame-shiftENST00000248342ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
Frame-shiftENST00000248342ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
Frame-shiftENST00000248342ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
Frame-shiftENST00000248342ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
Frame-shiftENST00000538434ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
Frame-shiftENST00000538434ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
Frame-shiftENST00000538434ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
Frame-shiftENST00000538434ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
Frame-shiftENST00000545173ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
Frame-shiftENST00000545173ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
Frame-shiftENST00000545173ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
Frame-shiftENST00000545173ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
Frame-shiftENST00000588934ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
Frame-shiftENST00000588934ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
Frame-shiftENST00000588934ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
Frame-shiftENST00000588934ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
Frame-shiftENST00000592558ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
Frame-shiftENST00000592558ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
Frame-shiftENST00000592558ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
Frame-shiftENST00000592558ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
Frame-shiftENST00000593149ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
Frame-shiftENST00000593149ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
Frame-shiftENST00000593149ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26227650

+
Frame-shiftENST00000593149ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26227649

+
In-frameENST00000248342ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
In-frameENST00000248342ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
In-frameENST00000538434ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
In-frameENST00000538434ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
In-frameENST00000545173ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
In-frameENST00000545173ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
In-frameENST00000588934ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
In-frameENST00000588934ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
In-frameENST00000592558ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
In-frameENST00000592558ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
In-frameENST00000593149ENST00000315985EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+
In-frameENST00000593149ENST00000380737EIF3Kchr19

39116742

+PPP2R2Achr8

26223831

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000593149EIF3Kchr1939116742+ENST00000380737PPP2R2Achr826223831+3063424145795216
ENST00000593149EIF3Kchr1939116742+ENST00000315985PPP2R2Achr826223831+1269424145795216
ENST00000248342EIF3Kchr1939116742+ENST00000380737PPP2R2Achr826223831+316552652897281
ENST00000248342EIF3Kchr1939116742+ENST00000315985PPP2R2Achr826223831+137152652897281
ENST00000538434EIF3Kchr1939116742+ENST00000380737PPP2R2Achr826223831+2967328181699172
ENST00000538434EIF3Kchr1939116742+ENST00000315985PPP2R2Achr826223831+1173328181699172
ENST00000588934EIF3Kchr1939116742+ENST00000380737PPP2R2Achr826223831+30764378808266
ENST00000588934EIF3Kchr1939116742+ENST00000315985PPP2R2Achr826223831+12824378808266
ENST00000545173EIF3Kchr1939116742+ENST00000380737PPP2R2Achr826223831+30694301801266
ENST00000545173EIF3Kchr1939116742+ENST00000315985PPP2R2Achr826223831+12754301801266
ENST00000592558EIF3Kchr1939116742+ENST00000380737PPP2R2Achr826223831+305141237783248
ENST00000592558EIF3Kchr1939116742+ENST00000315985PPP2R2Achr826223831+125741237783248

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000593149ENST00000380737EIF3Kchr1939116742+PPP2R2Achr826223831+0.0030647980.99693525
ENST00000593149ENST00000315985EIF3Kchr1939116742+PPP2R2Achr826223831+0.004552370.9954476
ENST00000248342ENST00000380737EIF3Kchr1939116742+PPP2R2Achr826223831+0.000632870.9993672
ENST00000248342ENST00000315985EIF3Kchr1939116742+PPP2R2Achr826223831+0.0017236310.99827635
ENST00000538434ENST00000380737EIF3Kchr1939116742+PPP2R2Achr826223831+0.0015523590.99844766
ENST00000538434ENST00000315985EIF3Kchr1939116742+PPP2R2Achr826223831+0.0030254390.9969746
ENST00000588934ENST00000380737EIF3Kchr1939116742+PPP2R2Achr826223831+0.0005914240.9994086
ENST00000588934ENST00000315985EIF3Kchr1939116742+PPP2R2Achr826223831+0.0012998520.99870014
ENST00000545173ENST00000380737EIF3Kchr1939116742+PPP2R2Achr826223831+0.0005880820.99941194
ENST00000545173ENST00000315985EIF3Kchr1939116742+PPP2R2Achr826223831+0.0012787740.9987212
ENST00000592558ENST00000380737EIF3Kchr1939116742+PPP2R2Achr826223831+0.0005915980.99940836
ENST00000592558ENST00000315985EIF3Kchr1939116742+PPP2R2Achr826223831+0.0012637930.9987362

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Fusion Genomic Features for EIF3K-PPP2R2A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
EIF3Kchr1939116742+PPP2R2Achr826223830+0.0047726120.99522734
EIF3Kchr1939116742+PPP2R2Achr826227649+0.0012855610.99871445
EIF3Kchr1939116742+PPP2R2Achr826227649+0.0012855610.99871445
EIF3Kchr1939116742+PPP2R2Achr826223830+0.0047726120.99522734
EIF3Kchr1939116742+PPP2R2Achr826227649+0.0012855610.99871445
EIF3Kchr1939116742+PPP2R2Achr826227649+0.0012855610.99871445

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for EIF3K-PPP2R2A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:39116742/chr8:26227650)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
EIF3K

Q9UBQ5

.
FUNCTION: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773). {ECO:0000255|HAMAP-Rule:MF_03010, ECO:0000269|PubMed:17581632, ECO:0000269|PubMed:25849773, ECO:0000269|PubMed:27462815}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePPP2R2Achr19:39116742chr8:26223831ENST00000315985710338_379334458.0RepeatNote=WD 6
TgenePPP2R2Achr19:39116742chr8:26223831ENST00000315985710414_446334458.0RepeatNote=WD 7
TgenePPP2R2Achr19:39116742chr8:26223831ENST00000380737710338_379324448.0RepeatNote=WD 6
TgenePPP2R2Achr19:39116742chr8:26223831ENST00000380737710414_446324448.0RepeatNote=WD 7

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEIF3Kchr19:39116742chr8:26223831ENST00000248342+4842_204118219.0DomainPCI
TgenePPP2R2Achr19:39116742chr8:26223831ENST00000315985710175_213334458.0RepeatNote=WD 3
TgenePPP2R2Achr19:39116742chr8:26223831ENST00000315985710224_264334458.0RepeatNote=WD 4
TgenePPP2R2Achr19:39116742chr8:26223831ENST0000031598571026_65334458.0RepeatNote=WD 1
TgenePPP2R2Achr19:39116742chr8:26223831ENST00000315985710283_321334458.0RepeatNote=WD 5
TgenePPP2R2Achr19:39116742chr8:26223831ENST0000031598571091_132334458.0RepeatNote=WD 2
TgenePPP2R2Achr19:39116742chr8:26223831ENST00000380737710175_213324448.0RepeatNote=WD 3
TgenePPP2R2Achr19:39116742chr8:26223831ENST00000380737710224_264324448.0RepeatNote=WD 4
TgenePPP2R2Achr19:39116742chr8:26223831ENST0000038073771026_65324448.0RepeatNote=WD 1
TgenePPP2R2Achr19:39116742chr8:26223831ENST00000380737710283_321324448.0RepeatNote=WD 5
TgenePPP2R2Achr19:39116742chr8:26223831ENST0000038073771091_132324448.0RepeatNote=WD 2


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Fusion Gene Sequence for EIF3K-PPP2R2A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>25888_25888_1_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000248342_PPP2R2A_chr8_26223831_ENST00000315985_length(transcript)=1371nt_BP=526nt
GGAAAGCGTGGCGGCTGCTGCTAGAGCCTTTCCCTTTACCGCACCCAAGGAGCTGGAGCGACAACAACGACGTCGTTTCCGTTTCCACCA
CCTCTTCCTGTTCCCGTCCTTGAGGACGCCGTGCCGGGTCAGTGTTAGCCTCCAGCCCTGGTTGTGGAAGGCGACAGAAGTCATGGCGAT
GTTTGAGCAGATGAGAGCCAACGTGGGCAAGTTGCTCAAGGGTATCGACAGGTACAATCCTGAGAACCTGGCCACCCTGGAGCGCTATGT
AGAGACGCAGGCCAAGGAAAATGCCTATGATCTGGAAGCCAACCTGGCTGTCCTGAAGCTGTACCAGTTCAACCCAGCCTTCTTTCAGAC
CACGGTCACCGCCCAGATCCTGCTGAAGGCCCTCACCAACTTGCCGCACACAGACTTCACCCTGTGCAAGTGCATGATCGACCAGGCACA
TCAAGAAGAACGGCCAATCCGACAGATTTTGTACCTCGGGGACCTGCTGGAGACCTGCCATTTCCAGGCCTTCTGGGTGCATGAATACCT
CAGAAGTAAACTCTGTTCACTGTATGAAAATGACTGCATATTTGACAAATTTGAATGTTGTTGGAATGGATCTGACAGTGTTGTCATGAC
TGGATCTTACAATAATTTCTTCAGAATGTTTGACAGAAACACAAAGCGAGACATAACCCTAGAAGCATCGCGGGAAAACAATAAGCCTCG
CACAGTTCTGAAGCCTCGCAAAGTCTGTGCAAGTGGCAAGCGAAAGAAAGATGAAATAAGTGTTGACAGCCTAGACTTCAATAAGAAAAT
CCTTCACACAGCCTGGCACCCCAAGGAAAATATCATTGCCGTAGCTACTACAAACAATCTGTATATATTTCAAGACAAAGTGAATTAGGG
TTGGCATTCCTAGCAGAAGAACCCACTTCCTGCTTAGTTGAGATAGTTGAATCTAGCATTCGTTCCTATAAAAGAGAGAGGTCCATTGTG
GCGCCCCTTTCCAGTGTTTGACAGTGTGCCATTCGACAACACATTGTTATAGCTACATGGAGAAAGCTCTGTGGATTCATCACTGTGGTG
TTCTCCATGTCTGCTAGCCATTTAGGTAAGGGTAGGGCACTTTTAATTTAAATGACTTCTTGCACCATCTTGCCTAATGGACTAGATTGG
ACTGTATCAACATTGATTTACTCCACTTTTTATGCCTTCCATTGTGATGACGTCAAACACAGTGAAAGCCTTCAGTCATGCTATGGGATT
TAATTGTGTATCCTCATTACTGTATCATTTGTGGGGTACACCCCTTCCCCCTTTTTTTAAATTAAATACAGCTCATTCTTACTGTGGCTT

>25888_25888_1_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000248342_PPP2R2A_chr8_26223831_ENST00000315985_length(amino acids)=281AA_BP=158
MERQQRRRFRFHHLFLFPSLRTPCRVSVSLQPWLWKATEVMAMFEQMRANVGKLLKGIDRYNPENLATLERYVETQAKENAYDLEANLAV
LKLYQFNPAFFQTTVTAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWVHEYLRSKLCSLYENDCIFDKF
ECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKILHTAWHPKENIIAVATT

--------------------------------------------------------------
>25888_25888_2_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000248342_PPP2R2A_chr8_26223831_ENST00000380737_length(transcript)=3165nt_BP=526nt
GGAAAGCGTGGCGGCTGCTGCTAGAGCCTTTCCCTTTACCGCACCCAAGGAGCTGGAGCGACAACAACGACGTCGTTTCCGTTTCCACCA
CCTCTTCCTGTTCCCGTCCTTGAGGACGCCGTGCCGGGTCAGTGTTAGCCTCCAGCCCTGGTTGTGGAAGGCGACAGAAGTCATGGCGAT
GTTTGAGCAGATGAGAGCCAACGTGGGCAAGTTGCTCAAGGGTATCGACAGGTACAATCCTGAGAACCTGGCCACCCTGGAGCGCTATGT
AGAGACGCAGGCCAAGGAAAATGCCTATGATCTGGAAGCCAACCTGGCTGTCCTGAAGCTGTACCAGTTCAACCCAGCCTTCTTTCAGAC
CACGGTCACCGCCCAGATCCTGCTGAAGGCCCTCACCAACTTGCCGCACACAGACTTCACCCTGTGCAAGTGCATGATCGACCAGGCACA
TCAAGAAGAACGGCCAATCCGACAGATTTTGTACCTCGGGGACCTGCTGGAGACCTGCCATTTCCAGGCCTTCTGGGTGCATGAATACCT
CAGAAGTAAACTCTGTTCACTGTATGAAAATGACTGCATATTTGACAAATTTGAATGTTGTTGGAATGGATCTGACAGTGTTGTCATGAC
TGGATCTTACAATAATTTCTTCAGAATGTTTGACAGAAACACAAAGCGAGACATAACCCTAGAAGCATCGCGGGAAAACAATAAGCCTCG
CACAGTTCTGAAGCCTCGCAAAGTCTGTGCAAGTGGCAAGCGAAAGAAAGATGAAATAAGTGTTGACAGCCTAGACTTCAATAAGAAAAT
CCTTCACACAGCCTGGCACCCCAAGGAAAATATCATTGCCGTAGCTACTACAAACAATCTGTATATATTTCAAGACAAAGTGAATTAGGG
TTGGCATTCCTAGCAGAAGAACCCACTTCCTGCTTAGTTGAGATAGTTGAATCTAGCATTCGTTCCTATAAAAGAGAGAGGTCCATTGTG
GCGCCCCTTTCCAGTGTTTGACAGTGTGCCATTCGACAACACATTGTTATAGCTACATGGAGAAAGCTCTGTGGATTCATCACTGTGGTG
TTCTCCATGTCTGCTAGCCATTTAGGTAAGGGTAGGGCACTTTTAATTTAAATGACTTCTTGCACCATCTTGCCTAATGGACTAGATTGG
ACTGTATCAACATTGATTTACTCCACTTTTTATGCCTTCCATTGTGATGACGTCAAACACAGTGAAAGCCTTCAGTCATGCTATGGGATT
TAATTGTGTATCCTCATTACTGTATCATTTGTGGGGTACACCCCTTCCCCCTTTTTTTAAATTAAATACAGCTCATTCTTACTGTGGCTT
GTAGCATTCCTCCTCTTCTGGCCTCCTGGACTGCTCCCCTTCATCTCTTACCCTTGCCCCCTCCACCCGGTCTTGGTGGTGGTATATTAA
AAAAAGAAAGAATGAAAGCACACAAAATGAGTCAGTTTGGGGTCAGTGGTATAAAGGGGGTATATGTTGCAAACAAATGTTTTAGTAACA
GTTGGCTGTAATCACTCCTCGCCGTGTCTGGCACTGAAAATAAGGAAAAAAAACCTACTACTGAATAAAAGTGACAAAGAATGGAGAATC
TGGTTTTCTTTTTCTTTTTAACCTACCTCTTGTAGCCAATATTTTGTGTCATACCTTTGGGCACAGTGAAACAAAATGGGTTTTCATTGT
TTATTGGTATTTTTGTTAATTATTTTTAACAAGTGTTCTTTTACATGCAGGAGGAGAGGTATTGGTTCTCTATGAACATATTTTGAATAT
AGGTTTTATTAAGGATTTCACAATCTATAAATGCTACTAGTTTTTTTTTTTTTTTTTACCATCATGAGGGTATTGGATACATTGTGTCTC
TATTTAACTCATTATGTGTTAATGAAATTGTTGTAAATGGGAACCAAATTTGTAGAACTTAATTTCTACTTTTTAGAGTGCTTAATTTCA
TTTTTGCCTTACTAAATAGTCAAAGACTTATAAAACATTTTTAACAAGTTAGAACTTTTTTGTTATTCAGTCATATAAAATAGCAGAAAA
CTAACATCAAGTGACACTGCACTAAATACTTTTTTTGTATTTTACTGCTATCAAATCAGAATGAAATATACTTTACCATAGATATTTTTC
TTCTATTTTTGGTTTTCCAAAGCTATATGAAAGACAAATTTTTAAAGGTACAGCGTTCAAAAAGTGCTTAATGAACTCCAACAGCTGCCT
CAAATAAAAATCTGTATATGAATACATTTTCCCTAAGCGGTGATACATTATCCAAAGATGAAGAGTGCTCCTATTTTTAATAGGTAGAAT
GTACCTTTGTCAGTCTTGCAGAAACTTTAATGGAGAAGAAATGGACTTTATTTTTGAAAGGTGAAATGAACAGGCATTTATATTATTAGA
GAATGGTAGTCTTATTTTGGTGGAACATAATGTAACAACCTTGAATTTCAGAGGACTCTGAGTGCTTCTATGTCCACTACCTATTGTTCT
ATTCTTCAATAATGAAAAAGAATTCAACGAGCCGACCGTGATTCCCTCTACTACAAATATTATGTCTTGTAAGTTAGCATTTTTAGCACA
CAGGAGAAATTTTATGTAATAAAATTACTGTATCTTTTGGATTTAACAAATTTGTATTTGAAACACATTCTATGTCTGATAATTCTTAAT
GGCACTTTTACTAATTTATTTGGGGATCTTGGGTACATTCTTAATTTGTGTTTATTCTTCACGCTTGACTTGCAAGTGGGATATTCCCCT
GCCACAAGTGTCAAACAGTGATATTCTTCCTGTGTTGTGACTGGACAGTTTTCCAGATCTTTTTTGGGAGATTTTCCTACAGCTTGGTTG
TATGTCTTGAGATAACACCACCAAACAGCTCTCAGAAATTCTTTTTTGATTGATCAGTAGCTATGATGATTCTCCTCCATGACACTAAGG
ATTAGTTTATATATTTAAGAGAAATAATTGCTAAAATTAAAATGCCTCTATCAAGGAATGCTATTATAAATTATTGTTAACATTCTCAAG
TATTAATTTTTTAATTTCATTGGTGTAGCAAACTCTAAGCCCAGCCACTCATTTTACATGGCCATGGTTAATCTTTTTATTAATAAAAAT

>25888_25888_2_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000248342_PPP2R2A_chr8_26223831_ENST00000380737_length(amino acids)=281AA_BP=158
MERQQRRRFRFHHLFLFPSLRTPCRVSVSLQPWLWKATEVMAMFEQMRANVGKLLKGIDRYNPENLATLERYVETQAKENAYDLEANLAV
LKLYQFNPAFFQTTVTAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWVHEYLRSKLCSLYENDCIFDKF
ECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVDSLDFNKKILHTAWHPKENIIAVATT

--------------------------------------------------------------
>25888_25888_3_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000538434_PPP2R2A_chr8_26223831_ENST00000315985_length(transcript)=1173nt_BP=328nt
ACCTCTTCCTGTTCCCGTCCTTGAGGACGCCGTGCCGGGTCAGTGTTAGCCTCCAGCCCTGGTTGTGGAAGGCGACAGAAGTCATGGCGA
TGTTTGAGCAGATGAGAGCCAACGTGGGCAAGTTGCTCAAGGGTACCAGTTCAACCCAGCCTTCTTTCAGACCACGGTCACCGCCCAGAT
CCTGCTGAAGGCCCTCACCAACTTGCCGCACACAGACTTCACCCTGTGCAAGTGCATGATCGACCAGGCACATCAAGAAGAACGGCCAAT
CCGACAGATTTTGTACCTCGGGGACCTGCTGGAGACCTGCCATTTCCAGGCCTTCTGGGTGCATGAATACCTCAGAAGTAAACTCTGTTC
ACTGTATGAAAATGACTGCATATTTGACAAATTTGAATGTTGTTGGAATGGATCTGACAGTGTTGTCATGACTGGATCTTACAATAATTT
CTTCAGAATGTTTGACAGAAACACAAAGCGAGACATAACCCTAGAAGCATCGCGGGAAAACAATAAGCCTCGCACAGTTCTGAAGCCTCG
CAAAGTCTGTGCAAGTGGCAAGCGAAAGAAAGATGAAATAAGTGTTGACAGCCTAGACTTCAATAAGAAAATCCTTCACACAGCCTGGCA
CCCCAAGGAAAATATCATTGCCGTAGCTACTACAAACAATCTGTATATATTTCAAGACAAAGTGAATTAGGGTTGGCATTCCTAGCAGAA
GAACCCACTTCCTGCTTAGTTGAGATAGTTGAATCTAGCATTCGTTCCTATAAAAGAGAGAGGTCCATTGTGGCGCCCCTTTCCAGTGTT
TGACAGTGTGCCATTCGACAACACATTGTTATAGCTACATGGAGAAAGCTCTGTGGATTCATCACTGTGGTGTTCTCCATGTCTGCTAGC
CATTTAGGTAAGGGTAGGGCACTTTTAATTTAAATGACTTCTTGCACCATCTTGCCTAATGGACTAGATTGGACTGTATCAACATTGATT
TACTCCACTTTTTATGCCTTCCATTGTGATGACGTCAAACACAGTGAAAGCCTTCAGTCATGCTATGGGATTTAATTGTGTATCCTCATT
ACTGTATCATTTGTGGGGTACACCCCTTCCCCCTTTTTTTAAATTAAATACAGCTCATTCTTACTGTGGCTTGTAGCATTCCTCCTCTTC

>25888_25888_3_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000538434_PPP2R2A_chr8_26223831_ENST00000315985_length(amino acids)=172AA_BP=49
MLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNF

--------------------------------------------------------------
>25888_25888_4_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000538434_PPP2R2A_chr8_26223831_ENST00000380737_length(transcript)=2967nt_BP=328nt
ACCTCTTCCTGTTCCCGTCCTTGAGGACGCCGTGCCGGGTCAGTGTTAGCCTCCAGCCCTGGTTGTGGAAGGCGACAGAAGTCATGGCGA
TGTTTGAGCAGATGAGAGCCAACGTGGGCAAGTTGCTCAAGGGTACCAGTTCAACCCAGCCTTCTTTCAGACCACGGTCACCGCCCAGAT
CCTGCTGAAGGCCCTCACCAACTTGCCGCACACAGACTTCACCCTGTGCAAGTGCATGATCGACCAGGCACATCAAGAAGAACGGCCAAT
CCGACAGATTTTGTACCTCGGGGACCTGCTGGAGACCTGCCATTTCCAGGCCTTCTGGGTGCATGAATACCTCAGAAGTAAACTCTGTTC
ACTGTATGAAAATGACTGCATATTTGACAAATTTGAATGTTGTTGGAATGGATCTGACAGTGTTGTCATGACTGGATCTTACAATAATTT
CTTCAGAATGTTTGACAGAAACACAAAGCGAGACATAACCCTAGAAGCATCGCGGGAAAACAATAAGCCTCGCACAGTTCTGAAGCCTCG
CAAAGTCTGTGCAAGTGGCAAGCGAAAGAAAGATGAAATAAGTGTTGACAGCCTAGACTTCAATAAGAAAATCCTTCACACAGCCTGGCA
CCCCAAGGAAAATATCATTGCCGTAGCTACTACAAACAATCTGTATATATTTCAAGACAAAGTGAATTAGGGTTGGCATTCCTAGCAGAA
GAACCCACTTCCTGCTTAGTTGAGATAGTTGAATCTAGCATTCGTTCCTATAAAAGAGAGAGGTCCATTGTGGCGCCCCTTTCCAGTGTT
TGACAGTGTGCCATTCGACAACACATTGTTATAGCTACATGGAGAAAGCTCTGTGGATTCATCACTGTGGTGTTCTCCATGTCTGCTAGC
CATTTAGGTAAGGGTAGGGCACTTTTAATTTAAATGACTTCTTGCACCATCTTGCCTAATGGACTAGATTGGACTGTATCAACATTGATT
TACTCCACTTTTTATGCCTTCCATTGTGATGACGTCAAACACAGTGAAAGCCTTCAGTCATGCTATGGGATTTAATTGTGTATCCTCATT
ACTGTATCATTTGTGGGGTACACCCCTTCCCCCTTTTTTTAAATTAAATACAGCTCATTCTTACTGTGGCTTGTAGCATTCCTCCTCTTC
TGGCCTCCTGGACTGCTCCCCTTCATCTCTTACCCTTGCCCCCTCCACCCGGTCTTGGTGGTGGTATATTAAAAAAAGAAAGAATGAAAG
CACACAAAATGAGTCAGTTTGGGGTCAGTGGTATAAAGGGGGTATATGTTGCAAACAAATGTTTTAGTAACAGTTGGCTGTAATCACTCC
TCGCCGTGTCTGGCACTGAAAATAAGGAAAAAAAACCTACTACTGAATAAAAGTGACAAAGAATGGAGAATCTGGTTTTCTTTTTCTTTT
TAACCTACCTCTTGTAGCCAATATTTTGTGTCATACCTTTGGGCACAGTGAAACAAAATGGGTTTTCATTGTTTATTGGTATTTTTGTTA
ATTATTTTTAACAAGTGTTCTTTTACATGCAGGAGGAGAGGTATTGGTTCTCTATGAACATATTTTGAATATAGGTTTTATTAAGGATTT
CACAATCTATAAATGCTACTAGTTTTTTTTTTTTTTTTTACCATCATGAGGGTATTGGATACATTGTGTCTCTATTTAACTCATTATGTG
TTAATGAAATTGTTGTAAATGGGAACCAAATTTGTAGAACTTAATTTCTACTTTTTAGAGTGCTTAATTTCATTTTTGCCTTACTAAATA
GTCAAAGACTTATAAAACATTTTTAACAAGTTAGAACTTTTTTGTTATTCAGTCATATAAAATAGCAGAAAACTAACATCAAGTGACACT
GCACTAAATACTTTTTTTGTATTTTACTGCTATCAAATCAGAATGAAATATACTTTACCATAGATATTTTTCTTCTATTTTTGGTTTTCC
AAAGCTATATGAAAGACAAATTTTTAAAGGTACAGCGTTCAAAAAGTGCTTAATGAACTCCAACAGCTGCCTCAAATAAAAATCTGTATA
TGAATACATTTTCCCTAAGCGGTGATACATTATCCAAAGATGAAGAGTGCTCCTATTTTTAATAGGTAGAATGTACCTTTGTCAGTCTTG
CAGAAACTTTAATGGAGAAGAAATGGACTTTATTTTTGAAAGGTGAAATGAACAGGCATTTATATTATTAGAGAATGGTAGTCTTATTTT
GGTGGAACATAATGTAACAACCTTGAATTTCAGAGGACTCTGAGTGCTTCTATGTCCACTACCTATTGTTCTATTCTTCAATAATGAAAA
AGAATTCAACGAGCCGACCGTGATTCCCTCTACTACAAATATTATGTCTTGTAAGTTAGCATTTTTAGCACACAGGAGAAATTTTATGTA
ATAAAATTACTGTATCTTTTGGATTTAACAAATTTGTATTTGAAACACATTCTATGTCTGATAATTCTTAATGGCACTTTTACTAATTTA
TTTGGGGATCTTGGGTACATTCTTAATTTGTGTTTATTCTTCACGCTTGACTTGCAAGTGGGATATTCCCCTGCCACAAGTGTCAAACAG
TGATATTCTTCCTGTGTTGTGACTGGACAGTTTTCCAGATCTTTTTTGGGAGATTTTCCTACAGCTTGGTTGTATGTCTTGAGATAACAC
CACCAAACAGCTCTCAGAAATTCTTTTTTGATTGATCAGTAGCTATGATGATTCTCCTCCATGACACTAAGGATTAGTTTATATATTTAA
GAGAAATAATTGCTAAAATTAAAATGCCTCTATCAAGGAATGCTATTATAAATTATTGTTAACATTCTCAAGTATTAATTTTTTAATTTC

>25888_25888_4_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000538434_PPP2R2A_chr8_26223831_ENST00000380737_length(amino acids)=172AA_BP=49
MLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNF

--------------------------------------------------------------
>25888_25888_5_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000545173_PPP2R2A_chr8_26223831_ENST00000315985_length(transcript)=1275nt_BP=430nt
CCTGTTCCCGTCCTTGAGGACGCCGTGCCGGGTCAGTGTTAGCCTCCAGCCCTGGTTGTGGAAGGCGACAGAAGTCATGGCGATGTTTGA
GCAGATGAGAGCCAACGTGGGCAAGTTGCTCAAGGGTATCGACAGGTACAATCCTGAGAACCTGGCCACCCTGGAGCGCTATGTAGAGAC
GCAGGCCAAGGAAAATGCCTATGATCTGGAAGCCAACCTGGCTGTCCTGAAGCTGTACCAGTTCAACCCAGCCTTCTTTCAGACCACGGT
CACCGCCCAGATCCTGCTGAAGGCCCTCACCAACTTGCCGCACACAGACTTCACCCTGTGCAAGTGCATGATCGACCAGGCACATCAAGA
AGAACGGCCAATCCGACAGATTTTGTACCTCGGGGACCTGCTGGAGACCTGCCATTTCCAGGCCTTCTGGGTGCATGAATACCTCAGAAG
TAAACTCTGTTCACTGTATGAAAATGACTGCATATTTGACAAATTTGAATGTTGTTGGAATGGATCTGACAGTGTTGTCATGACTGGATC
TTACAATAATTTCTTCAGAATGTTTGACAGAAACACAAAGCGAGACATAACCCTAGAAGCATCGCGGGAAAACAATAAGCCTCGCACAGT
TCTGAAGCCTCGCAAAGTCTGTGCAAGTGGCAAGCGAAAGAAAGATGAAATAAGTGTTGACAGCCTAGACTTCAATAAGAAAATCCTTCA
CACAGCCTGGCACCCCAAGGAAAATATCATTGCCGTAGCTACTACAAACAATCTGTATATATTTCAAGACAAAGTGAATTAGGGTTGGCA
TTCCTAGCAGAAGAACCCACTTCCTGCTTAGTTGAGATAGTTGAATCTAGCATTCGTTCCTATAAAAGAGAGAGGTCCATTGTGGCGCCC
CTTTCCAGTGTTTGACAGTGTGCCATTCGACAACACATTGTTATAGCTACATGGAGAAAGCTCTGTGGATTCATCACTGTGGTGTTCTCC
ATGTCTGCTAGCCATTTAGGTAAGGGTAGGGCACTTTTAATTTAAATGACTTCTTGCACCATCTTGCCTAATGGACTAGATTGGACTGTA
TCAACATTGATTTACTCCACTTTTTATGCCTTCCATTGTGATGACGTCAAACACAGTGAAAGCCTTCAGTCATGCTATGGGATTTAATTG
TGTATCCTCATTACTGTATCATTTGTGGGGTACACCCCTTCCCCCTTTTTTTAAATTAAATACAGCTCATTCTTACTGTGGCTTGTAGCA

>25888_25888_5_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000545173_PPP2R2A_chr8_26223831_ENST00000315985_length(amino acids)=266AA_BP=143
LFPSLRTPCRVSVSLQPWLWKATEVMAMFEQMRANVGKLLKGIDRYNPENLATLERYVETQAKENAYDLEANLAVLKLYQFNPAFFQTTV
TAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGS

--------------------------------------------------------------
>25888_25888_6_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000545173_PPP2R2A_chr8_26223831_ENST00000380737_length(transcript)=3069nt_BP=430nt
CCTGTTCCCGTCCTTGAGGACGCCGTGCCGGGTCAGTGTTAGCCTCCAGCCCTGGTTGTGGAAGGCGACAGAAGTCATGGCGATGTTTGA
GCAGATGAGAGCCAACGTGGGCAAGTTGCTCAAGGGTATCGACAGGTACAATCCTGAGAACCTGGCCACCCTGGAGCGCTATGTAGAGAC
GCAGGCCAAGGAAAATGCCTATGATCTGGAAGCCAACCTGGCTGTCCTGAAGCTGTACCAGTTCAACCCAGCCTTCTTTCAGACCACGGT
CACCGCCCAGATCCTGCTGAAGGCCCTCACCAACTTGCCGCACACAGACTTCACCCTGTGCAAGTGCATGATCGACCAGGCACATCAAGA
AGAACGGCCAATCCGACAGATTTTGTACCTCGGGGACCTGCTGGAGACCTGCCATTTCCAGGCCTTCTGGGTGCATGAATACCTCAGAAG
TAAACTCTGTTCACTGTATGAAAATGACTGCATATTTGACAAATTTGAATGTTGTTGGAATGGATCTGACAGTGTTGTCATGACTGGATC
TTACAATAATTTCTTCAGAATGTTTGACAGAAACACAAAGCGAGACATAACCCTAGAAGCATCGCGGGAAAACAATAAGCCTCGCACAGT
TCTGAAGCCTCGCAAAGTCTGTGCAAGTGGCAAGCGAAAGAAAGATGAAATAAGTGTTGACAGCCTAGACTTCAATAAGAAAATCCTTCA
CACAGCCTGGCACCCCAAGGAAAATATCATTGCCGTAGCTACTACAAACAATCTGTATATATTTCAAGACAAAGTGAATTAGGGTTGGCA
TTCCTAGCAGAAGAACCCACTTCCTGCTTAGTTGAGATAGTTGAATCTAGCATTCGTTCCTATAAAAGAGAGAGGTCCATTGTGGCGCCC
CTTTCCAGTGTTTGACAGTGTGCCATTCGACAACACATTGTTATAGCTACATGGAGAAAGCTCTGTGGATTCATCACTGTGGTGTTCTCC
ATGTCTGCTAGCCATTTAGGTAAGGGTAGGGCACTTTTAATTTAAATGACTTCTTGCACCATCTTGCCTAATGGACTAGATTGGACTGTA
TCAACATTGATTTACTCCACTTTTTATGCCTTCCATTGTGATGACGTCAAACACAGTGAAAGCCTTCAGTCATGCTATGGGATTTAATTG
TGTATCCTCATTACTGTATCATTTGTGGGGTACACCCCTTCCCCCTTTTTTTAAATTAAATACAGCTCATTCTTACTGTGGCTTGTAGCA
TTCCTCCTCTTCTGGCCTCCTGGACTGCTCCCCTTCATCTCTTACCCTTGCCCCCTCCACCCGGTCTTGGTGGTGGTATATTAAAAAAAG
AAAGAATGAAAGCACACAAAATGAGTCAGTTTGGGGTCAGTGGTATAAAGGGGGTATATGTTGCAAACAAATGTTTTAGTAACAGTTGGC
TGTAATCACTCCTCGCCGTGTCTGGCACTGAAAATAAGGAAAAAAAACCTACTACTGAATAAAAGTGACAAAGAATGGAGAATCTGGTTT
TCTTTTTCTTTTTAACCTACCTCTTGTAGCCAATATTTTGTGTCATACCTTTGGGCACAGTGAAACAAAATGGGTTTTCATTGTTTATTG
GTATTTTTGTTAATTATTTTTAACAAGTGTTCTTTTACATGCAGGAGGAGAGGTATTGGTTCTCTATGAACATATTTTGAATATAGGTTT
TATTAAGGATTTCACAATCTATAAATGCTACTAGTTTTTTTTTTTTTTTTTACCATCATGAGGGTATTGGATACATTGTGTCTCTATTTA
ACTCATTATGTGTTAATGAAATTGTTGTAAATGGGAACCAAATTTGTAGAACTTAATTTCTACTTTTTAGAGTGCTTAATTTCATTTTTG
CCTTACTAAATAGTCAAAGACTTATAAAACATTTTTAACAAGTTAGAACTTTTTTGTTATTCAGTCATATAAAATAGCAGAAAACTAACA
TCAAGTGACACTGCACTAAATACTTTTTTTGTATTTTACTGCTATCAAATCAGAATGAAATATACTTTACCATAGATATTTTTCTTCTAT
TTTTGGTTTTCCAAAGCTATATGAAAGACAAATTTTTAAAGGTACAGCGTTCAAAAAGTGCTTAATGAACTCCAACAGCTGCCTCAAATA
AAAATCTGTATATGAATACATTTTCCCTAAGCGGTGATACATTATCCAAAGATGAAGAGTGCTCCTATTTTTAATAGGTAGAATGTACCT
TTGTCAGTCTTGCAGAAACTTTAATGGAGAAGAAATGGACTTTATTTTTGAAAGGTGAAATGAACAGGCATTTATATTATTAGAGAATGG
TAGTCTTATTTTGGTGGAACATAATGTAACAACCTTGAATTTCAGAGGACTCTGAGTGCTTCTATGTCCACTACCTATTGTTCTATTCTT
CAATAATGAAAAAGAATTCAACGAGCCGACCGTGATTCCCTCTACTACAAATATTATGTCTTGTAAGTTAGCATTTTTAGCACACAGGAG
AAATTTTATGTAATAAAATTACTGTATCTTTTGGATTTAACAAATTTGTATTTGAAACACATTCTATGTCTGATAATTCTTAATGGCACT
TTTACTAATTTATTTGGGGATCTTGGGTACATTCTTAATTTGTGTTTATTCTTCACGCTTGACTTGCAAGTGGGATATTCCCCTGCCACA
AGTGTCAAACAGTGATATTCTTCCTGTGTTGTGACTGGACAGTTTTCCAGATCTTTTTTGGGAGATTTTCCTACAGCTTGGTTGTATGTC
TTGAGATAACACCACCAAACAGCTCTCAGAAATTCTTTTTTGATTGATCAGTAGCTATGATGATTCTCCTCCATGACACTAAGGATTAGT
TTATATATTTAAGAGAAATAATTGCTAAAATTAAAATGCCTCTATCAAGGAATGCTATTATAAATTATTGTTAACATTCTCAAGTATTAA
TTTTTTAATTTCATTGGTGTAGCAAACTCTAAGCCCAGCCACTCATTTTACATGGCCATGGTTAATCTTTTTATTAATAAAAATTATACT

>25888_25888_6_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000545173_PPP2R2A_chr8_26223831_ENST00000380737_length(amino acids)=266AA_BP=143
LFPSLRTPCRVSVSLQPWLWKATEVMAMFEQMRANVGKLLKGIDRYNPENLATLERYVETQAKENAYDLEANLAVLKLYQFNPAFFQTTV
TAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGS

--------------------------------------------------------------
>25888_25888_7_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000588934_PPP2R2A_chr8_26223831_ENST00000315985_length(transcript)=1282nt_BP=437nt
ACCTCTTCCTGTTCCCGTCCTTGAGGACGCCGTGCCGGGTCAGTGTTAGCCTCCAGCCCTGGTTGTGGAAGGCGACAGAAGTCATGGCGA
TGTTTGAGCAGATGAGAGCCAACGTGGGCAAGTTGCTCAAGGGTATCGACAGGTACAATCCTGAGAACCTGGCCACCCTGGAGCGCTATG
TAGAGACGCAGGCCAAGGAAAATGCCTATGATCTGGAAGCCAACCTGGCTGTCCTGAAGCTGTACCAGTTCAACCCAGCCTTCTTTCAGA
CCACGGTCACCGCCCAGATCCTGCTGAAGGCCCTCACCAACTTGCCGCACACAGACTTCACCCTGTGCAAGTGCATGATCGACCAGGCAC
ATCAAGAAGAACGGCCAATCCGACAGATTTTGTACCTCGGGGACCTGCTGGAGACCTGCCATTTCCAGGCCTTCTGGGTGCATGAATACC
TCAGAAGTAAACTCTGTTCACTGTATGAAAATGACTGCATATTTGACAAATTTGAATGTTGTTGGAATGGATCTGACAGTGTTGTCATGA
CTGGATCTTACAATAATTTCTTCAGAATGTTTGACAGAAACACAAAGCGAGACATAACCCTAGAAGCATCGCGGGAAAACAATAAGCCTC
GCACAGTTCTGAAGCCTCGCAAAGTCTGTGCAAGTGGCAAGCGAAAGAAAGATGAAATAAGTGTTGACAGCCTAGACTTCAATAAGAAAA
TCCTTCACACAGCCTGGCACCCCAAGGAAAATATCATTGCCGTAGCTACTACAAACAATCTGTATATATTTCAAGACAAAGTGAATTAGG
GTTGGCATTCCTAGCAGAAGAACCCACTTCCTGCTTAGTTGAGATAGTTGAATCTAGCATTCGTTCCTATAAAAGAGAGAGGTCCATTGT
GGCGCCCCTTTCCAGTGTTTGACAGTGTGCCATTCGACAACACATTGTTATAGCTACATGGAGAAAGCTCTGTGGATTCATCACTGTGGT
GTTCTCCATGTCTGCTAGCCATTTAGGTAAGGGTAGGGCACTTTTAATTTAAATGACTTCTTGCACCATCTTGCCTAATGGACTAGATTG
GACTGTATCAACATTGATTTACTCCACTTTTTATGCCTTCCATTGTGATGACGTCAAACACAGTGAAAGCCTTCAGTCATGCTATGGGAT
TTAATTGTGTATCCTCATTACTGTATCATTTGTGGGGTACACCCCTTCCCCCTTTTTTTAAATTAAATACAGCTCATTCTTACTGTGGCT

>25888_25888_7_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000588934_PPP2R2A_chr8_26223831_ENST00000315985_length(amino acids)=266AA_BP=143
MFPSLRTPCRVSVSLQPWLWKATEVMAMFEQMRANVGKLLKGIDRYNPENLATLERYVETQAKENAYDLEANLAVLKLYQFNPAFFQTTV
TAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGS

--------------------------------------------------------------
>25888_25888_8_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000588934_PPP2R2A_chr8_26223831_ENST00000380737_length(transcript)=3076nt_BP=437nt
ACCTCTTCCTGTTCCCGTCCTTGAGGACGCCGTGCCGGGTCAGTGTTAGCCTCCAGCCCTGGTTGTGGAAGGCGACAGAAGTCATGGCGA
TGTTTGAGCAGATGAGAGCCAACGTGGGCAAGTTGCTCAAGGGTATCGACAGGTACAATCCTGAGAACCTGGCCACCCTGGAGCGCTATG
TAGAGACGCAGGCCAAGGAAAATGCCTATGATCTGGAAGCCAACCTGGCTGTCCTGAAGCTGTACCAGTTCAACCCAGCCTTCTTTCAGA
CCACGGTCACCGCCCAGATCCTGCTGAAGGCCCTCACCAACTTGCCGCACACAGACTTCACCCTGTGCAAGTGCATGATCGACCAGGCAC
ATCAAGAAGAACGGCCAATCCGACAGATTTTGTACCTCGGGGACCTGCTGGAGACCTGCCATTTCCAGGCCTTCTGGGTGCATGAATACC
TCAGAAGTAAACTCTGTTCACTGTATGAAAATGACTGCATATTTGACAAATTTGAATGTTGTTGGAATGGATCTGACAGTGTTGTCATGA
CTGGATCTTACAATAATTTCTTCAGAATGTTTGACAGAAACACAAAGCGAGACATAACCCTAGAAGCATCGCGGGAAAACAATAAGCCTC
GCACAGTTCTGAAGCCTCGCAAAGTCTGTGCAAGTGGCAAGCGAAAGAAAGATGAAATAAGTGTTGACAGCCTAGACTTCAATAAGAAAA
TCCTTCACACAGCCTGGCACCCCAAGGAAAATATCATTGCCGTAGCTACTACAAACAATCTGTATATATTTCAAGACAAAGTGAATTAGG
GTTGGCATTCCTAGCAGAAGAACCCACTTCCTGCTTAGTTGAGATAGTTGAATCTAGCATTCGTTCCTATAAAAGAGAGAGGTCCATTGT
GGCGCCCCTTTCCAGTGTTTGACAGTGTGCCATTCGACAACACATTGTTATAGCTACATGGAGAAAGCTCTGTGGATTCATCACTGTGGT
GTTCTCCATGTCTGCTAGCCATTTAGGTAAGGGTAGGGCACTTTTAATTTAAATGACTTCTTGCACCATCTTGCCTAATGGACTAGATTG
GACTGTATCAACATTGATTTACTCCACTTTTTATGCCTTCCATTGTGATGACGTCAAACACAGTGAAAGCCTTCAGTCATGCTATGGGAT
TTAATTGTGTATCCTCATTACTGTATCATTTGTGGGGTACACCCCTTCCCCCTTTTTTTAAATTAAATACAGCTCATTCTTACTGTGGCT
TGTAGCATTCCTCCTCTTCTGGCCTCCTGGACTGCTCCCCTTCATCTCTTACCCTTGCCCCCTCCACCCGGTCTTGGTGGTGGTATATTA
AAAAAAGAAAGAATGAAAGCACACAAAATGAGTCAGTTTGGGGTCAGTGGTATAAAGGGGGTATATGTTGCAAACAAATGTTTTAGTAAC
AGTTGGCTGTAATCACTCCTCGCCGTGTCTGGCACTGAAAATAAGGAAAAAAAACCTACTACTGAATAAAAGTGACAAAGAATGGAGAAT
CTGGTTTTCTTTTTCTTTTTAACCTACCTCTTGTAGCCAATATTTTGTGTCATACCTTTGGGCACAGTGAAACAAAATGGGTTTTCATTG
TTTATTGGTATTTTTGTTAATTATTTTTAACAAGTGTTCTTTTACATGCAGGAGGAGAGGTATTGGTTCTCTATGAACATATTTTGAATA
TAGGTTTTATTAAGGATTTCACAATCTATAAATGCTACTAGTTTTTTTTTTTTTTTTTACCATCATGAGGGTATTGGATACATTGTGTCT
CTATTTAACTCATTATGTGTTAATGAAATTGTTGTAAATGGGAACCAAATTTGTAGAACTTAATTTCTACTTTTTAGAGTGCTTAATTTC
ATTTTTGCCTTACTAAATAGTCAAAGACTTATAAAACATTTTTAACAAGTTAGAACTTTTTTGTTATTCAGTCATATAAAATAGCAGAAA
ACTAACATCAAGTGACACTGCACTAAATACTTTTTTTGTATTTTACTGCTATCAAATCAGAATGAAATATACTTTACCATAGATATTTTT
CTTCTATTTTTGGTTTTCCAAAGCTATATGAAAGACAAATTTTTAAAGGTACAGCGTTCAAAAAGTGCTTAATGAACTCCAACAGCTGCC
TCAAATAAAAATCTGTATATGAATACATTTTCCCTAAGCGGTGATACATTATCCAAAGATGAAGAGTGCTCCTATTTTTAATAGGTAGAA
TGTACCTTTGTCAGTCTTGCAGAAACTTTAATGGAGAAGAAATGGACTTTATTTTTGAAAGGTGAAATGAACAGGCATTTATATTATTAG
AGAATGGTAGTCTTATTTTGGTGGAACATAATGTAACAACCTTGAATTTCAGAGGACTCTGAGTGCTTCTATGTCCACTACCTATTGTTC
TATTCTTCAATAATGAAAAAGAATTCAACGAGCCGACCGTGATTCCCTCTACTACAAATATTATGTCTTGTAAGTTAGCATTTTTAGCAC
ACAGGAGAAATTTTATGTAATAAAATTACTGTATCTTTTGGATTTAACAAATTTGTATTTGAAACACATTCTATGTCTGATAATTCTTAA
TGGCACTTTTACTAATTTATTTGGGGATCTTGGGTACATTCTTAATTTGTGTTTATTCTTCACGCTTGACTTGCAAGTGGGATATTCCCC
TGCCACAAGTGTCAAACAGTGATATTCTTCCTGTGTTGTGACTGGACAGTTTTCCAGATCTTTTTTGGGAGATTTTCCTACAGCTTGGTT
GTATGTCTTGAGATAACACCACCAAACAGCTCTCAGAAATTCTTTTTTGATTGATCAGTAGCTATGATGATTCTCCTCCATGACACTAAG
GATTAGTTTATATATTTAAGAGAAATAATTGCTAAAATTAAAATGCCTCTATCAAGGAATGCTATTATAAATTATTGTTAACATTCTCAA
GTATTAATTTTTTAATTTCATTGGTGTAGCAAACTCTAAGCCCAGCCACTCATTTTACATGGCCATGGTTAATCTTTTTATTAATAAAAA

>25888_25888_8_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000588934_PPP2R2A_chr8_26223831_ENST00000380737_length(amino acids)=266AA_BP=143
MFPSLRTPCRVSVSLQPWLWKATEVMAMFEQMRANVGKLLKGIDRYNPENLATLERYVETQAKENAYDLEANLAVLKLYQFNPAFFQTTV
TAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGS

--------------------------------------------------------------
>25888_25888_9_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000592558_PPP2R2A_chr8_26223831_ENST00000315985_length(transcript)=1257nt_BP=412nt
GACGCCGTGCCGGGTCAGTGTTAGCCTCCAGCCCTGGTTGTGGAAGGCGACAGAAGTCATGGCGATGTTTGAGCAGATGAGAGCCAACGT
GGGCAAGTTGCTCAAGGGTATCGACAGGTACAATCCTGAGAACCTGGCCACCCTGGAGCGCTATGTAGAGACGCAGGCCAAGGAAAATGC
CTATGATCTGGAAGCCAACCTGGCTGTCCTGAAGCTGTACCAGTTCAACCCAGCCTTCTTTCAGACCACGGTCACCGCCCAGATCCTGCT
GAAGGCCCTCACCAACTTGCCGCACACAGACTTCACCCTGTGCAAGTGCATGATCGACCAGGCACATCAAGAAGAACGGCCAATCCGACA
GATTTTGTACCTCGGGGACCTGCTGGAGACCTGCCATTTCCAGGCCTTCTGGGTGCATGAATACCTCAGAAGTAAACTCTGTTCACTGTA
TGAAAATGACTGCATATTTGACAAATTTGAATGTTGTTGGAATGGATCTGACAGTGTTGTCATGACTGGATCTTACAATAATTTCTTCAG
AATGTTTGACAGAAACACAAAGCGAGACATAACCCTAGAAGCATCGCGGGAAAACAATAAGCCTCGCACAGTTCTGAAGCCTCGCAAAGT
CTGTGCAAGTGGCAAGCGAAAGAAAGATGAAATAAGTGTTGACAGCCTAGACTTCAATAAGAAAATCCTTCACACAGCCTGGCACCCCAA
GGAAAATATCATTGCCGTAGCTACTACAAACAATCTGTATATATTTCAAGACAAAGTGAATTAGGGTTGGCATTCCTAGCAGAAGAACCC
ACTTCCTGCTTAGTTGAGATAGTTGAATCTAGCATTCGTTCCTATAAAAGAGAGAGGTCCATTGTGGCGCCCCTTTCCAGTGTTTGACAG
TGTGCCATTCGACAACACATTGTTATAGCTACATGGAGAAAGCTCTGTGGATTCATCACTGTGGTGTTCTCCATGTCTGCTAGCCATTTA
GGTAAGGGTAGGGCACTTTTAATTTAAATGACTTCTTGCACCATCTTGCCTAATGGACTAGATTGGACTGTATCAACATTGATTTACTCC
ACTTTTTATGCCTTCCATTGTGATGACGTCAAACACAGTGAAAGCCTTCAGTCATGCTATGGGATTTAATTGTGTATCCTCATTACTGTA

>25888_25888_9_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000592558_PPP2R2A_chr8_26223831_ENST00000315985_length(amino acids)=248AA_BP=125
MWKATEVMAMFEQMRANVGKLLKGIDRYNPENLATLERYVETQAKENAYDLEANLAVLKLYQFNPAFFQTTVTAQILLKALTNLPHTDFT
LCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITL

--------------------------------------------------------------
>25888_25888_10_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000592558_PPP2R2A_chr8_26223831_ENST00000380737_length(transcript)=3051nt_BP=412nt
GACGCCGTGCCGGGTCAGTGTTAGCCTCCAGCCCTGGTTGTGGAAGGCGACAGAAGTCATGGCGATGTTTGAGCAGATGAGAGCCAACGT
GGGCAAGTTGCTCAAGGGTATCGACAGGTACAATCCTGAGAACCTGGCCACCCTGGAGCGCTATGTAGAGACGCAGGCCAAGGAAAATGC
CTATGATCTGGAAGCCAACCTGGCTGTCCTGAAGCTGTACCAGTTCAACCCAGCCTTCTTTCAGACCACGGTCACCGCCCAGATCCTGCT
GAAGGCCCTCACCAACTTGCCGCACACAGACTTCACCCTGTGCAAGTGCATGATCGACCAGGCACATCAAGAAGAACGGCCAATCCGACA
GATTTTGTACCTCGGGGACCTGCTGGAGACCTGCCATTTCCAGGCCTTCTGGGTGCATGAATACCTCAGAAGTAAACTCTGTTCACTGTA
TGAAAATGACTGCATATTTGACAAATTTGAATGTTGTTGGAATGGATCTGACAGTGTTGTCATGACTGGATCTTACAATAATTTCTTCAG
AATGTTTGACAGAAACACAAAGCGAGACATAACCCTAGAAGCATCGCGGGAAAACAATAAGCCTCGCACAGTTCTGAAGCCTCGCAAAGT
CTGTGCAAGTGGCAAGCGAAAGAAAGATGAAATAAGTGTTGACAGCCTAGACTTCAATAAGAAAATCCTTCACACAGCCTGGCACCCCAA
GGAAAATATCATTGCCGTAGCTACTACAAACAATCTGTATATATTTCAAGACAAAGTGAATTAGGGTTGGCATTCCTAGCAGAAGAACCC
ACTTCCTGCTTAGTTGAGATAGTTGAATCTAGCATTCGTTCCTATAAAAGAGAGAGGTCCATTGTGGCGCCCCTTTCCAGTGTTTGACAG
TGTGCCATTCGACAACACATTGTTATAGCTACATGGAGAAAGCTCTGTGGATTCATCACTGTGGTGTTCTCCATGTCTGCTAGCCATTTA
GGTAAGGGTAGGGCACTTTTAATTTAAATGACTTCTTGCACCATCTTGCCTAATGGACTAGATTGGACTGTATCAACATTGATTTACTCC
ACTTTTTATGCCTTCCATTGTGATGACGTCAAACACAGTGAAAGCCTTCAGTCATGCTATGGGATTTAATTGTGTATCCTCATTACTGTA
TCATTTGTGGGGTACACCCCTTCCCCCTTTTTTTAAATTAAATACAGCTCATTCTTACTGTGGCTTGTAGCATTCCTCCTCTTCTGGCCT
CCTGGACTGCTCCCCTTCATCTCTTACCCTTGCCCCCTCCACCCGGTCTTGGTGGTGGTATATTAAAAAAAGAAAGAATGAAAGCACACA
AAATGAGTCAGTTTGGGGTCAGTGGTATAAAGGGGGTATATGTTGCAAACAAATGTTTTAGTAACAGTTGGCTGTAATCACTCCTCGCCG
TGTCTGGCACTGAAAATAAGGAAAAAAAACCTACTACTGAATAAAAGTGACAAAGAATGGAGAATCTGGTTTTCTTTTTCTTTTTAACCT
ACCTCTTGTAGCCAATATTTTGTGTCATACCTTTGGGCACAGTGAAACAAAATGGGTTTTCATTGTTTATTGGTATTTTTGTTAATTATT
TTTAACAAGTGTTCTTTTACATGCAGGAGGAGAGGTATTGGTTCTCTATGAACATATTTTGAATATAGGTTTTATTAAGGATTTCACAAT
CTATAAATGCTACTAGTTTTTTTTTTTTTTTTTACCATCATGAGGGTATTGGATACATTGTGTCTCTATTTAACTCATTATGTGTTAATG
AAATTGTTGTAAATGGGAACCAAATTTGTAGAACTTAATTTCTACTTTTTAGAGTGCTTAATTTCATTTTTGCCTTACTAAATAGTCAAA
GACTTATAAAACATTTTTAACAAGTTAGAACTTTTTTGTTATTCAGTCATATAAAATAGCAGAAAACTAACATCAAGTGACACTGCACTA
AATACTTTTTTTGTATTTTACTGCTATCAAATCAGAATGAAATATACTTTACCATAGATATTTTTCTTCTATTTTTGGTTTTCCAAAGCT
ATATGAAAGACAAATTTTTAAAGGTACAGCGTTCAAAAAGTGCTTAATGAACTCCAACAGCTGCCTCAAATAAAAATCTGTATATGAATA
CATTTTCCCTAAGCGGTGATACATTATCCAAAGATGAAGAGTGCTCCTATTTTTAATAGGTAGAATGTACCTTTGTCAGTCTTGCAGAAA
CTTTAATGGAGAAGAAATGGACTTTATTTTTGAAAGGTGAAATGAACAGGCATTTATATTATTAGAGAATGGTAGTCTTATTTTGGTGGA
ACATAATGTAACAACCTTGAATTTCAGAGGACTCTGAGTGCTTCTATGTCCACTACCTATTGTTCTATTCTTCAATAATGAAAAAGAATT
CAACGAGCCGACCGTGATTCCCTCTACTACAAATATTATGTCTTGTAAGTTAGCATTTTTAGCACACAGGAGAAATTTTATGTAATAAAA
TTACTGTATCTTTTGGATTTAACAAATTTGTATTTGAAACACATTCTATGTCTGATAATTCTTAATGGCACTTTTACTAATTTATTTGGG
GATCTTGGGTACATTCTTAATTTGTGTTTATTCTTCACGCTTGACTTGCAAGTGGGATATTCCCCTGCCACAAGTGTCAAACAGTGATAT
TCTTCCTGTGTTGTGACTGGACAGTTTTCCAGATCTTTTTTGGGAGATTTTCCTACAGCTTGGTTGTATGTCTTGAGATAACACCACCAA
ACAGCTCTCAGAAATTCTTTTTTGATTGATCAGTAGCTATGATGATTCTCCTCCATGACACTAAGGATTAGTTTATATATTTAAGAGAAA
TAATTGCTAAAATTAAAATGCCTCTATCAAGGAATGCTATTATAAATTATTGTTAACATTCTCAAGTATTAATTTTTTAATTTCATTGGT

>25888_25888_10_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000592558_PPP2R2A_chr8_26223831_ENST00000380737_length(amino acids)=248AA_BP=125
MWKATEVMAMFEQMRANVGKLLKGIDRYNPENLATLERYVETQAKENAYDLEANLAVLKLYQFNPAFFQTTVTAQILLKALTNLPHTDFT
LCKCMIDQAHQEERPIRQILYLGDLLETCHFQAFWVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITL

--------------------------------------------------------------
>25888_25888_11_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000593149_PPP2R2A_chr8_26223831_ENST00000315985_length(transcript)=1269nt_BP=424nt
CCGGAAAGCGTGGCGGCTGCTGCTAGAGCCTTTCCCTTTACCGCACCCAAGGAGCTGGAGCGACAACAACGACGTCGTTTCCGTTTCCAC
CACCTCTTCCTGTTCCCGTCCTTGAGGACGCCGTGCCGGGTACAATCCTGAGAACCTGGCCACCCTGGAGCGCTATGTAGAGACGCAGGC
CAAGGAAAATGCCTATGATCTGGAAGCCAACCTGGCTGTCCTGAAGCTGTACCAGTTCAACCCAGCCTTCTTTCAGACCACGGTCACCGC
CCAGATCCTGCTGAAGGCCCTCACCAACTTGCCGCACACAGACTTCACCCTGTGCAAGTGCATGATCGACCAGGCACATCAAGAAGAACG
GCCAATCCGACAGATTTTGTACCTCGGGGACCTGCTGGAGACCTGCCATTTCCAGGCCTTCTGGGTGCATGAATACCTCAGAAGTAAACT
CTGTTCACTGTATGAAAATGACTGCATATTTGACAAATTTGAATGTTGTTGGAATGGATCTGACAGTGTTGTCATGACTGGATCTTACAA
TAATTTCTTCAGAATGTTTGACAGAAACACAAAGCGAGACATAACCCTAGAAGCATCGCGGGAAAACAATAAGCCTCGCACAGTTCTGAA
GCCTCGCAAAGTCTGTGCAAGTGGCAAGCGAAAGAAAGATGAAATAAGTGTTGACAGCCTAGACTTCAATAAGAAAATCCTTCACACAGC
CTGGCACCCCAAGGAAAATATCATTGCCGTAGCTACTACAAACAATCTGTATATATTTCAAGACAAAGTGAATTAGGGTTGGCATTCCTA
GCAGAAGAACCCACTTCCTGCTTAGTTGAGATAGTTGAATCTAGCATTCGTTCCTATAAAAGAGAGAGGTCCATTGTGGCGCCCCTTTCC
AGTGTTTGACAGTGTGCCATTCGACAACACATTGTTATAGCTACATGGAGAAAGCTCTGTGGATTCATCACTGTGGTGTTCTCCATGTCT
GCTAGCCATTTAGGTAAGGGTAGGGCACTTTTAATTTAAATGACTTCTTGCACCATCTTGCCTAATGGACTAGATTGGACTGTATCAACA
TTGATTTACTCCACTTTTTATGCCTTCCATTGTGATGACGTCAAACACAGTGAAAGCCTTCAGTCATGCTATGGGATTTAATTGTGTATC
CTCATTACTGTATCATTTGTGGGGTACACCCCTTCCCCCTTTTTTTAAATTAAATACAGCTCATTCTTACTGTGGCTTGTAGCATTCCTC

>25888_25888_11_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000593149_PPP2R2A_chr8_26223831_ENST00000315985_length(amino acids)=216AA_BP=93
MATLERYVETQAKENAYDLEANLAVLKLYQFNPAFFQTTVTAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQ
AFWVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVD

--------------------------------------------------------------
>25888_25888_12_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000593149_PPP2R2A_chr8_26223831_ENST00000380737_length(transcript)=3063nt_BP=424nt
CCGGAAAGCGTGGCGGCTGCTGCTAGAGCCTTTCCCTTTACCGCACCCAAGGAGCTGGAGCGACAACAACGACGTCGTTTCCGTTTCCAC
CACCTCTTCCTGTTCCCGTCCTTGAGGACGCCGTGCCGGGTACAATCCTGAGAACCTGGCCACCCTGGAGCGCTATGTAGAGACGCAGGC
CAAGGAAAATGCCTATGATCTGGAAGCCAACCTGGCTGTCCTGAAGCTGTACCAGTTCAACCCAGCCTTCTTTCAGACCACGGTCACCGC
CCAGATCCTGCTGAAGGCCCTCACCAACTTGCCGCACACAGACTTCACCCTGTGCAAGTGCATGATCGACCAGGCACATCAAGAAGAACG
GCCAATCCGACAGATTTTGTACCTCGGGGACCTGCTGGAGACCTGCCATTTCCAGGCCTTCTGGGTGCATGAATACCTCAGAAGTAAACT
CTGTTCACTGTATGAAAATGACTGCATATTTGACAAATTTGAATGTTGTTGGAATGGATCTGACAGTGTTGTCATGACTGGATCTTACAA
TAATTTCTTCAGAATGTTTGACAGAAACACAAAGCGAGACATAACCCTAGAAGCATCGCGGGAAAACAATAAGCCTCGCACAGTTCTGAA
GCCTCGCAAAGTCTGTGCAAGTGGCAAGCGAAAGAAAGATGAAATAAGTGTTGACAGCCTAGACTTCAATAAGAAAATCCTTCACACAGC
CTGGCACCCCAAGGAAAATATCATTGCCGTAGCTACTACAAACAATCTGTATATATTTCAAGACAAAGTGAATTAGGGTTGGCATTCCTA
GCAGAAGAACCCACTTCCTGCTTAGTTGAGATAGTTGAATCTAGCATTCGTTCCTATAAAAGAGAGAGGTCCATTGTGGCGCCCCTTTCC
AGTGTTTGACAGTGTGCCATTCGACAACACATTGTTATAGCTACATGGAGAAAGCTCTGTGGATTCATCACTGTGGTGTTCTCCATGTCT
GCTAGCCATTTAGGTAAGGGTAGGGCACTTTTAATTTAAATGACTTCTTGCACCATCTTGCCTAATGGACTAGATTGGACTGTATCAACA
TTGATTTACTCCACTTTTTATGCCTTCCATTGTGATGACGTCAAACACAGTGAAAGCCTTCAGTCATGCTATGGGATTTAATTGTGTATC
CTCATTACTGTATCATTTGTGGGGTACACCCCTTCCCCCTTTTTTTAAATTAAATACAGCTCATTCTTACTGTGGCTTGTAGCATTCCTC
CTCTTCTGGCCTCCTGGACTGCTCCCCTTCATCTCTTACCCTTGCCCCCTCCACCCGGTCTTGGTGGTGGTATATTAAAAAAAGAAAGAA
TGAAAGCACACAAAATGAGTCAGTTTGGGGTCAGTGGTATAAAGGGGGTATATGTTGCAAACAAATGTTTTAGTAACAGTTGGCTGTAAT
CACTCCTCGCCGTGTCTGGCACTGAAAATAAGGAAAAAAAACCTACTACTGAATAAAAGTGACAAAGAATGGAGAATCTGGTTTTCTTTT
TCTTTTTAACCTACCTCTTGTAGCCAATATTTTGTGTCATACCTTTGGGCACAGTGAAACAAAATGGGTTTTCATTGTTTATTGGTATTT
TTGTTAATTATTTTTAACAAGTGTTCTTTTACATGCAGGAGGAGAGGTATTGGTTCTCTATGAACATATTTTGAATATAGGTTTTATTAA
GGATTTCACAATCTATAAATGCTACTAGTTTTTTTTTTTTTTTTTACCATCATGAGGGTATTGGATACATTGTGTCTCTATTTAACTCAT
TATGTGTTAATGAAATTGTTGTAAATGGGAACCAAATTTGTAGAACTTAATTTCTACTTTTTAGAGTGCTTAATTTCATTTTTGCCTTAC
TAAATAGTCAAAGACTTATAAAACATTTTTAACAAGTTAGAACTTTTTTGTTATTCAGTCATATAAAATAGCAGAAAACTAACATCAAGT
GACACTGCACTAAATACTTTTTTTGTATTTTACTGCTATCAAATCAGAATGAAATATACTTTACCATAGATATTTTTCTTCTATTTTTGG
TTTTCCAAAGCTATATGAAAGACAAATTTTTAAAGGTACAGCGTTCAAAAAGTGCTTAATGAACTCCAACAGCTGCCTCAAATAAAAATC
TGTATATGAATACATTTTCCCTAAGCGGTGATACATTATCCAAAGATGAAGAGTGCTCCTATTTTTAATAGGTAGAATGTACCTTTGTCA
GTCTTGCAGAAACTTTAATGGAGAAGAAATGGACTTTATTTTTGAAAGGTGAAATGAACAGGCATTTATATTATTAGAGAATGGTAGTCT
TATTTTGGTGGAACATAATGTAACAACCTTGAATTTCAGAGGACTCTGAGTGCTTCTATGTCCACTACCTATTGTTCTATTCTTCAATAA
TGAAAAAGAATTCAACGAGCCGACCGTGATTCCCTCTACTACAAATATTATGTCTTGTAAGTTAGCATTTTTAGCACACAGGAGAAATTT
TATGTAATAAAATTACTGTATCTTTTGGATTTAACAAATTTGTATTTGAAACACATTCTATGTCTGATAATTCTTAATGGCACTTTTACT
AATTTATTTGGGGATCTTGGGTACATTCTTAATTTGTGTTTATTCTTCACGCTTGACTTGCAAGTGGGATATTCCCCTGCCACAAGTGTC
AAACAGTGATATTCTTCCTGTGTTGTGACTGGACAGTTTTCCAGATCTTTTTTGGGAGATTTTCCTACAGCTTGGTTGTATGTCTTGAGA
TAACACCACCAAACAGCTCTCAGAAATTCTTTTTTGATTGATCAGTAGCTATGATGATTCTCCTCCATGACACTAAGGATTAGTTTATAT
ATTTAAGAGAAATAATTGCTAAAATTAAAATGCCTCTATCAAGGAATGCTATTATAAATTATTGTTAACATTCTCAAGTATTAATTTTTT
AATTTCATTGGTGTAGCAAACTCTAAGCCCAGCCACTCATTTTACATGGCCATGGTTAATCTTTTTATTAATAAAAATTATACTTAGAAT

>25888_25888_12_EIF3K-PPP2R2A_EIF3K_chr19_39116742_ENST00000593149_PPP2R2A_chr8_26223831_ENST00000380737_length(amino acids)=216AA_BP=93
MATLERYVETQAKENAYDLEANLAVLKLYQFNPAFFQTTVTAQILLKALTNLPHTDFTLCKCMIDQAHQEERPIRQILYLGDLLETCHFQ
AFWVHEYLRSKLCSLYENDCIFDKFECCWNGSDSVVMTGSYNNFFRMFDRNTKRDITLEASRENNKPRTVLKPRKVCASGKRKKDEISVD

--------------------------------------------------------------

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Fusion Gene PPI Analysis for EIF3K-PPP2R2A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for EIF3K-PPP2R2A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for EIF3K-PPP2R2A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource