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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:EIF3M-UEVLD (FusionGDB2 ID:25918)

Fusion Gene Summary for EIF3M-UEVLD

check button Fusion gene summary
Fusion gene informationFusion gene name: EIF3M-UEVLD
Fusion gene ID: 25918
HgeneTgene
Gene symbol

EIF3M

UEVLD

Gene ID

10480

55293

Gene nameeukaryotic translation initiation factor 3 subunit MUEV and lactate/malate dehyrogenase domains
SynonymsB5|GA17|PCID1|TANGO7|hfl-B5ATTP|UEV3
Cytomap

11p13

11p15.1

Type of geneprotein-codingprotein-coding
Descriptioneukaryotic translation initiation factor 3 subunit MB5 receptorPCI domain containing 1 (herpesvirus entry mediator)PCI domain-containing protein 1dendritic cell proteinfetal lung protein B5transport and golgi organization 7 homologubiquitin-conjugating enzyme E2 variant 3EV and lactate/malate dehydrogenase domain-containing proteinUEV-3signaling molecule ATTP
Modification date2020031320200313
UniProtAcc

Q7L2H7

.
Ensembl transtripts involved in fusion geneENST00000524896, ENST00000531120, 
ENST00000532054, 		ENST00000300038, 
ENST00000320750, ENST00000379387, 
ENST00000535484, ENST00000540666, 
ENST00000541984, ENST00000396197, 
ENST00000543987, 
Fusion gene scores* DoF score9 X 9 X 4=3243 X 3 X 3=27
# samples 103
** MAII scorelog2(10/324*10)=-1.6959938131099
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(3/27*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: EIF3M [Title/Abstract] AND UEVLD [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEIF3M(32617593)-UEVLD(18591924), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across EIF3M (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across UEVLD (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-DX-A1KU-01AEIF3Mchr11

32617593

-UEVLDchr11

18591924

-
ChimerDB4SARCTCGA-DX-A1KU-01AEIF3Mchr11

32617593

+UEVLDchr11

18591924

-
ChimerDB4SARCTCGA-DX-A1KUEIF3Mchr11

32617593

+UEVLDchr11

18591924

-


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Fusion Gene ORF analysis for EIF3M-UEVLD

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000524896ENST00000300038EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
5CDS-intronENST00000524896ENST00000320750EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
5CDS-intronENST00000524896ENST00000379387EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
5CDS-intronENST00000524896ENST00000535484EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
5CDS-intronENST00000524896ENST00000540666EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
5CDS-intronENST00000524896ENST00000541984EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
5CDS-intronENST00000531120ENST00000300038EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
5CDS-intronENST00000531120ENST00000320750EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
5CDS-intronENST00000531120ENST00000379387EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
5CDS-intronENST00000531120ENST00000535484EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
5CDS-intronENST00000531120ENST00000540666EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
5CDS-intronENST00000531120ENST00000541984EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
In-frameENST00000524896ENST00000396197EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
In-frameENST00000524896ENST00000543987EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
In-frameENST00000531120ENST00000396197EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
In-frameENST00000531120ENST00000543987EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
intron-3CDSENST00000532054ENST00000396197EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
intron-3CDSENST00000532054ENST00000543987EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
intron-intronENST00000532054ENST00000300038EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
intron-intronENST00000532054ENST00000320750EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
intron-intronENST00000532054ENST00000379387EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
intron-intronENST00000532054ENST00000535484EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
intron-intronENST00000532054ENST00000540666EIF3Mchr11

32617593

+UEVLDchr11

18591924

-
intron-intronENST00000532054ENST00000541984EIF3Mchr11

32617593

+UEVLDchr11

18591924

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000531120EIF3Mchr1132617593+ENST00000396197UEVLDchr1118591924-4796862632084673
ENST00000531120EIF3Mchr1132617593+ENST00000543987UEVLDchr1118591924-3080862631808581
ENST00000524896EIF3Mchr1132617593+ENST00000396197UEVLDchr1118591924-4391457541679541
ENST00000524896EIF3Mchr1132617593+ENST00000543987UEVLDchr1118591924-2675457541403449

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000531120ENST00000396197EIF3Mchr1132617593+UEVLDchr1118591924-9.71E-050.99990296
ENST00000531120ENST00000543987EIF3Mchr1132617593+UEVLDchr1118591924-0.0001249280.99987507
ENST00000524896ENST00000396197EIF3Mchr1132617593+UEVLDchr1118591924-0.0001696160.99983037
ENST00000524896ENST00000543987EIF3Mchr1132617593+UEVLDchr1118591924-0.0001850870.9998149

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Fusion Genomic Features for EIF3M-UEVLD


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for EIF3M-UEVLD


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:32617593/chr11:18591924)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
EIF3M

Q7L2H7

.
FUNCTION: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17403899, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17403899). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773). {ECO:0000255|HAMAP-Rule:MF_03012, ECO:0000269|PubMed:17403899, ECO:0000269|PubMed:25849773, ECO:0000269|PubMed:27462815}.; FUNCTION: (Microbial infection) May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2). {ECO:0000269|PubMed:15919898}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneUEVLDchr11:32617593chr11:18591924ENST00000541984072_1450200.0DomainUEV
TgeneUEVLDchr11:32617593chr11:18591924ENST0000030003827191_21964216.0Nucleotide bindingNAD
TgeneUEVLDchr11:32617593chr11:18591924ENST00000320750110191_21942358.0Nucleotide bindingNAD
TgeneUEVLDchr11:32617593chr11:18591924ENST00000379387111191_21942450.0Nucleotide bindingNAD
TgeneUEVLDchr11:32617593chr11:18591924ENST00000396197212191_21964472.0Nucleotide bindingNAD
TgeneUEVLDchr11:32617593chr11:18591924ENST00000535484211191_21926342.0Nucleotide bindingNAD
TgeneUEVLDchr11:32617593chr11:18591924ENST0000054198407191_2190200.0Nucleotide bindingNAD
TgeneUEVLDchr11:32617593chr11:18591924ENST00000543987211191_21964380.0Nucleotide bindingNAD

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEIF3Mchr11:32617593chr11:18591924ENST00000531120+811180_339266375.0DomainPCI
TgeneUEVLDchr11:32617593chr11:18591924ENST00000300038272_14564216.0DomainUEV
TgeneUEVLDchr11:32617593chr11:18591924ENST000003207501102_14542358.0DomainUEV
TgeneUEVLDchr11:32617593chr11:18591924ENST000003793871112_14542450.0DomainUEV
TgeneUEVLDchr11:32617593chr11:18591924ENST000003961972122_14564472.0DomainUEV
TgeneUEVLDchr11:32617593chr11:18591924ENST000005354842112_14526342.0DomainUEV
TgeneUEVLDchr11:32617593chr11:18591924ENST000005439872112_14564380.0DomainUEV


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Fusion Gene Sequence for EIF3M-UEVLD


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>25918_25918_1_EIF3M-UEVLD_EIF3M_chr11_32617593_ENST00000524896_UEVLD_chr11_18591924_ENST00000396197_length(transcript)=4391nt_BP=457nt
TTCCGGTCGGCGTGGTCTTGCGAGTGGAGTGTCCGCTGTGCCCGGGCCTGCACCATGAGCGTCCCGGCCTTCATCGACATCAGTGAAGAA
GATCAGGTTAGAAAATGGATTTCTGACTGGAATCTCACCACTGAAAAAAAGCACACCCTTTTAAGACTACTTTATGAGGCACTTGTGGAT
TGTAAGAAGAGTGATGCTGCTTCAAAAGTCATGGTGGAATTGCTCGGAAGTTACACAGAGGACAATGCTTCCCAGGCTCGAGTTGATGCC
CACAGGTGTATTGTACGAGCATTGAAAGATCCAAATGCATTTCTTTTTGACCACCTTCTTACTTTAAAACCAGTCAAGTTTTTGGAAGGC
GAGCTTATTCATGATCTTTTAACCATTTTTGTGAGTGCTAAATTGGCATCATATGTCAAGTTTTATCAGAATAATAAAGACTTCATTGAT
TCACTTGGTAATACATATAACATACCAATTCGTTTCTGGATTTTGGATTCTCACCCTTTCGCTCCCCCTATTTGCTTCTTGAAGCCAACT
GCAAATATGGGAATCTTAGTCGGAAAACATGTGGATGCTCAAGGCAGAATATATTTGCCCTATCTCCAAAACTGGAGCCATCCTAAATCT
GTCATTGTTGGATTAATTAAAGAAATGATTGCCAAGTTTCAAGAGGAACTTCCCATGTATTCTCTATCATCATCTGATGAGGCACGGCAG
GTAGACTTGCTAGCCTATATTGCAAAAATCACTGAAGGTGTTTCAGATACAAATTCAAAGAGCTGGGCAAATCATGAGAATAAAACAGTC
AATAAAATTACTGTGGTTGGAGGTGGAGAACTCGGTATTGCCTGCACATTAGCAATTTCAGCAAAGGGTATTGCAGACAGGCTTGTCCTC
TTAGACCTCTCAGAAGGGACTAAAGGAGCCACGATGGACCTTGAAATCTTCAACCTTCCTAATGTGGAGATCAGCAAAGATTTGTCTGCC
TCTGCTCATTCCAAGGTGGTGATCTTCACAGTCAACTCTTTGGGTAGTTCTCAGTCGTACCTTGATGTGGTACAGAGCAATGTGGATATG
TTCAGAGCCCTTGTCCCAGCTCTGGGACATTATAGTCAACACAGTGTCCTGCTCGTTGCATCTCAACCAGTGGAAATCATGACCTATGTA
ACATGGAAACTGAGTACATTTCCTGCAAATCGAGTGATCGGAATTGGATGTAATCTGGATTCACAGAGATTACAGTATATTATTACAAAT
GTTTTGAAGGCACAGACTTCAGGCAAAGAAGTATGGGTTATTGGCGAGCAAGGAGAAGACAAAGTGCTCACATGGAGTGGCCAAGAAGAA
GTAGTGAGTCATACCTCTCAAGTGCAGCTGTCCAACAGAGCCATGGAACTGCTAAGAGTAAAAGGTCAAAGATCCTGGTCTGTTGGACTA
TCAGTAGCTGACATGGTTGACAGTATTGTAAACAATAAGAAGAAAGTGCATTCTGTATCAGCTTTAGCAAAGGGATATTATGATATAAAT
AGTGAAGTGTTTTTAAGTTTGCCTTGCATCCTTGGAACCAATGGAGTATCTGAAGTTATCAAAACCACACTGAAAGAAGATACAGTTACT
GAGAAACTCCAAAGCAGTGCATCCTCAATCCACAGTCTCCAACAACAGTTAAAACTTTGATTCTCAAATGCAATTTGAGAGGCTGGACTT
CTACCTAAAGGGAAAAGTCATTTAATTTTACCTATATATAGGTTTGAGGATTTCTGTATCCTGCTACTTACTTTTACAAACTGCTTGGTT
AAAGTAGAGGGTTTCTTGATTAGCTTTGTGATGTAAATCCTTAAGGAGTTATACAAGGAGGGGAAAAATTAATTTTATTTGGGGTTCTTG
AGATATCTATGCTGTTCTTTAAATCTACAGCAGGGGTAAACATTCATCTGCAGTGTGCATCAATTTAAATCATATATCCTAAACTAAAAG
CACAATTCATACTTCGGGAATATTTTATAAGTAATATATCTTTAAAAGAAAATTACCCTTTGACTTTTATAATCAACATAAGTTCCAGGC
CCAGTATGGATTTACAAAATCTGTGTCAGTTGTACATTCACAGGATCCACAGCTTAAGTTACTAATGTTTCTTGTGTAAAATCCTGTTGG
TAGTAATAGTAAAGCATTGTATTTCCCTTCTTCAAATTAATTACCTACCAAAAAATGGAAAAGAATTTTACATGCACTTTAAAATAGTAA
AATGGAAAGTGAATTTTTAAAATATATGCATTAAAAGTTTACTTTAATTTCCAGTGGGACTTCCTTTATGAAATTTTCCATAACCTCTTC
CTGGAGTATTACAAGATCTCCAACATCTCATAAACTAATTGTGATATTAGTGGAACCATAAGCAAATATATATTTTTAGTGGAAATAGAT
TATGAATGAAAGCCAAGCACCTTACTTTAAAGCCAAAATATGAGATTTTCATTAAAAACATTGGTCATAATAGGGAGAGGTTTTTTATTT
GTTCTGAGCAAATCCTTTAACCTCTCCTGATGATACAGTTCAGAGTACACACACTTTGGTGATGGATCAAGAGCAATATTTTCTTATGTG
AAAGATAGCTTATTATTACTATTGTGACATACAACTAATAGTAACAGTTAACATCAACACTTCATATATACCAGGCAGCATGATAAGCAC
TTTATTATTTTACTGAATCCTCACAACAGACCACTGAGGTAGGGACTATTGCCATCATCATTTTATAAAAGGAAATTGAGGTTTAGTCCT
CAAGAAGTCTTGGCTATTAAGGGGCACTTATCCATACAACCTCTACTTTTTCTAGGCACTAAAAGGGGGAAAAGGCTTAATAGCCAAAAT
AGTTATCAAAAGACCCTAAAGCTGGGGTCCTGTACACCATGAAAGGATTACTTTCATTCTCATGTAAGGGCATGCTTTTATAAAAAACAA
ACATGGGCTAGGCGCAGTGACTCACGCCTGTAATCCCAGCACCTTGGGAGGCTGAGGCGGGCAGATCACGAGGTCAGGAGATTGAGATCA
TCCTGGCTAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAAGTTAGCCAGGCGTGGTGGCAGGTGCCTGTAGTCCCAGCTACTCG
GAAGGCTGAGGCAAGAGAATGGCGTGAACCCGGTAGGTGGAGCTTGCAGTGAGCAGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAG
AGCAAGACTCCGTCTCAAAAAAAAAAAAAAAAAGTTTAAAAATTAGCCAGGTGTGGTGATGTGCACCTGTAGTTCCAGCTACTCAGGAGG
GTGAGGCAGGAGGATCACTTGAGCCCAGAAGTTCAAGATTGCAATGAGCTATGATCATGCTACTGCACTCCAGCCTAGGCAACAGAGTGA
GACCCTGTCTCTAAAAAAATAAAAATAAAGCAAGCATATAATAGGTTAATCCAGATGGAGTTAGGAGGGTTTATAAGGGCAGACACATCC
TAGTAAAGAGGAAATAGGCAAACTAATGCTGTTTTAGTGTAATAAGGAATGCTTATAATGATGAACTTTAGTCATAAAGAAAAGGTGAAA
TTATATTCAGTAACCCATGTTAGGAAAGCAGAAAACTATTTAATATGCTTGGAAAGATTCCAACCAGAGTTAACTGAATAAAAACCTTGG
ACATTTGAAGAGAAAAGCATTTAGTTCTATCTAATTTCAATATGCACGTGAATTAGTTCATGTTACTCTAACAATGTATTCTTACTGTCC
TTTTTTATGAAATAGGAAAGTAAAACTGAAAGAACTATTTCTTGTGTTTTTAAAACTAGCCTTTTCTAATATTTGATATCTAATTAAAGT
TAGATAATATGTAATATGCTTTTGAACAATAATCTAACCAGAAAATATTGTATAATAAATTACCAAGAAATCATTACATTAATTATAAAA
GGAACATGTCAATACAACAAATGTTTATTTAACACCTACTGTTACTCCAAATACTGTGTTAGAATTTGACTATTCGAAGATGAATAATAG
TCTTTGCCCTCTGGAAGGCCACAATGTAGAAGTAATTCTCTGTATCAGATATTTCCTTGAGTGTTAAGTGTATTAGTAATCATGTTGTAA
ATCCCAGTGTAAGTCAAGAAGCAATATCACCACCACCACCTCCCTATGATTTTGTGATAATTTGGCATTTTCAATGCTTGTTAACTTTCA
TGTTTTCATTTTTATGAAATCATGCAGAGCTTGTTATAATTTTTAGTGGGGTTTGGATTAAAATGCTTTTTTGATGTAGCAGAAGATACA

>25918_25918_1_EIF3M-UEVLD_EIF3M_chr11_32617593_ENST00000524896_UEVLD_chr11_18591924_ENST00000396197_length(amino acids)=541AA_BP=134
MSVPAFIDISEEDQVRKWISDWNLTTEKKHTLLRLLYEALVDCKKSDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDH
LLTLKPVKFLEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGNTYNIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIY
LPYLQNWSHPKSVIVGLIKEMIAKFQEELPMYSLSSSDEARQVDLLAYIAKITEGVSDTNSKSWANHENKTVNKITVVGGGELGIACTLA
ISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEISKDLSASAHSKVVIFTVNSLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLL
VASQPVEIMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIGEQGEDKVLTWSGQEEVVSHTSQVQLSNRAMELL
RVKGQRSWSVGLSVADMVDSIVNNKKKVHSVSALAKGYYDINSEVFLSLPCILGTNGVSEVIKTTLKEDTVTEKLQSSASSIHSLQQQLK

--------------------------------------------------------------
>25918_25918_2_EIF3M-UEVLD_EIF3M_chr11_32617593_ENST00000524896_UEVLD_chr11_18591924_ENST00000543987_length(transcript)=2675nt_BP=457nt
TTCCGGTCGGCGTGGTCTTGCGAGTGGAGTGTCCGCTGTGCCCGGGCCTGCACCATGAGCGTCCCGGCCTTCATCGACATCAGTGAAGAA
GATCAGGTTAGAAAATGGATTTCTGACTGGAATCTCACCACTGAAAAAAAGCACACCCTTTTAAGACTACTTTATGAGGCACTTGTGGAT
TGTAAGAAGAGTGATGCTGCTTCAAAAGTCATGGTGGAATTGCTCGGAAGTTACACAGAGGACAATGCTTCCCAGGCTCGAGTTGATGCC
CACAGGTGTATTGTACGAGCATTGAAAGATCCAAATGCATTTCTTTTTGACCACCTTCTTACTTTAAAACCAGTCAAGTTTTTGGAAGGC
GAGCTTATTCATGATCTTTTAACCATTTTTGTGAGTGCTAAATTGGCATCATATGTCAAGTTTTATCAGAATAATAAAGACTTCATTGAT
TCACTTGGTAATACATATAACATACCAATTCGTTTCTGGATTTTGGATTCTCACCCTTTCGCTCCCCCTATTTGCTTCTTGAAGCCAACT
GCAAATATGGGAATCTTAGTCGGAAAACATGTGGATGCTCAAGGCAGAATATATTTGCCCTATCTCCAAAACTGGAGCCATCCTAAATCT
GTCATTGTTGGATTAATTAAAGAAATGATTGCCAAGTTTCAAGAGGAACTTCCCATGTATTCTCTATCATCATCTGATGAGGCACGGCAG
GTAGACTTGCTAGCCTATATTGCAAAAATCACTGAAGGTGTTTCAGATACAAATTCAAAGAGCTGGGCAAATCATGAGAATAAAACAGTC
AATAAAATTACTGTGGTTGGAGGTGGAGAACTCGGTATTGCCTGCACATTAGCAATTTCAGCAAAGGGTATTGCAGACAGGCTTGTCCTC
TTAGACCTCTCAGAAGGGACTAAAGGAGCCACGATGGACCTTGAAATCTTCAACCTTCCTAATGTGGAGATCAGCAAAGATTTGTCTGCC
TCTGCTCATTCCAAGGTGGTGATCTTCACAGTCAACTCTTTGGGTAGTTCTCAGTCGTACCTTGATGTGGTACAGAGCAATGTGGATATG
TTCAGAGCCCTTGTCCCAGCTCTGGGACATTATAGTCAACACAGTGTCCTGCTCGTTGCATCTCAACCAGTGGAAATCATGACCTATGTA
ACATGGAAACTGAGTACATTTCCTGCAAATCGAGTGATCGGAATTGGATGTAATCTGGATTCACAGAGATTACAGTATATTATTACAAAT
GTTTTGAAGGCACAGACTTCAGGCAAAGAAGTATGGGTTATTGGCGAGCAAGGAGAAGACAAAGTGCTCACATGGAGTGGCCAAGAAGAA
GTAGTGAGTCATACCTCTCAAGTGCAGCTGTCCAACAGGGATATTATGATATAAATAGTGAAGTGTTTTTAAGTTTGCCTTGCATCCTTG
GAACCAATGGAGTATCTGAAGTTATCAAAACCACACTGAAAGAAGATACAGTTACTGAGAAACTCCAAAGCAGTGCATCCTCAATCCACA
GTCTCCAACAACAGTTAAAACTTTGATTCTCAAATGCAATTTGAGAGGCTGGACTTCTACCTAAAGGGAAAAGTCATTTAATTTTACCTA
TATATAGGTTTGAGGATTTCTGTATCCTGCTACTTACTTTTACAAACTGCTTGGTTAAAGTAGAGGGTTTCTTGATTAGCTTTGTGATGT
AAATCCTTAAGGAGTTATACAAGGAGGGGAAAAATTAATTTTATTTGGGGTTCTTGAGATATCTATGCTGTTCTTTAAATCTACAGCAGG
GGTAAACATTCATCTGCAGTGTGCATCAATTTAAATCATATATCCTAAACTAAAAGCACAATTCATACTTCGGGAATATTTTATAAGTAA
TATATCTTTAAAAGAAAATTACCCTTTGACTTTTATAATCAACATAAGTTCCAGGCCCAGTATGGATTTACAAAATCTGTGTCAGTTGTA
CATTCACAGGATCCACAGCTTAAGTTACTAATGTTTCTTGTGTAAAATCCTGTTGGTAGTAATAGTAAAGCATTGTATTTCCCTTCTTCA
AATTAATTACCTACCAAAAAATGGAAAAGAATTTTACATGCACTTTAAAATAGTAAAATGGAAAGTGAATTTTTAAAATATATGCATTAA
AAGTTTACTTTAATTTCCAGTGGGACTTCCTTTATGAAATTTTCCATAACCTCTTCCTGGAGTATTACAAGATCTCCAACATCTCATAAA
CTAATTGTGATATTAGTGGAACCATAAGCAAATATATATTTTTAGTGGAAATAGATTATGAATGAAAGCCAAGCACCTTACTTTAAAGCC
AAAATATGAGATTTTCATTAAAAACATTGGTCATAATAGGGAGAGGTTTTTTATTTGTTCTGAGCAAATCCTTTAACCTCTCCTGATGAT
ACAGTTCAGAGTACACACACTTTGGTGATGGATCAAGAGCAATATTTTCTTATGTGAAAGATAGCTTATTATTACTATTGTGACATACAA
CTAATAGTAACAGTTAACATCAACACTTCATATATACCAGGCAGCATGATAAGCACTTTATTATTTTACTGAATCCTCACAACAGACCAC

>25918_25918_2_EIF3M-UEVLD_EIF3M_chr11_32617593_ENST00000524896_UEVLD_chr11_18591924_ENST00000543987_length(amino acids)=449AA_BP=134
MSVPAFIDISEEDQVRKWISDWNLTTEKKHTLLRLLYEALVDCKKSDAASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDH
LLTLKPVKFLEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGNTYNIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIY
LPYLQNWSHPKSVIVGLIKEMIAKFQEELPMYSLSSSDEARQVDLLAYIAKITEGVSDTNSKSWANHENKTVNKITVVGGGELGIACTLA
ISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEISKDLSASAHSKVVIFTVNSLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLL

--------------------------------------------------------------
>25918_25918_3_EIF3M-UEVLD_EIF3M_chr11_32617593_ENST00000531120_UEVLD_chr11_18591924_ENST00000396197_length(transcript)=4796nt_BP=862nt
AGTTCCCTTTTCCGGTCGGCGTGGTCTTGCGAGTGGAGTGTCCGCTGTGCCCGGGCCTGCACCATGAGCGTCCCGGCCTTCATCGACATC
AGTGAAGAAGATCAGGCTGCTGAGCTTCGTGCTTATCTGAAATCTAAAGGAGCTGAGATTTCAGAAGAGAACTCGGAAGGTGGACTTCAT
GTTGATTTAGCTCAAATTATTGAAGCCTGTGATGTGTGTCTGAAGGAGGATGATAAAGATGTTGAAAGTGTGATGAACAGTGTGGTATCC
CTACTCTTGATCCTGGAACCAGACAAGCAAGAAGCTTTGATTGAAAGCCTATGTGAAAAGCTGGTCAAATTTCGCGAAGGTGAACGCCCG
TCTCTGAGACTGCAGTTGTTAAGCAACCTTTTCCACGGGATGGATAAGAATACTCCTGTAAGATACACAGTGTATTGCAGCCTTATTAAA
GTGGCAGCATCTTGTGGGGCCATCCAGTACATCCCAACTGAGCTGGATCAAGTTAGAAAATGGATTTCTGACTGGAATCTCACCACTGAA
AAAAAGCACACCCTTTTAAGACTACTTTATGAGGCACTTGTGGATTGTAAGAAGAGTGATGCTGCTTCAAAAGTCATGGTGGAATTGCTC
GGAAGTTACACAGAGGACAATGCTTCCCAGGCTCGAGTTGATGCCCACAGGTGTATTGTACGAGCATTGAAAGATCCAAATGCATTTCTT
TTTGACCACCTTCTTACTTTAAAACCAGTCAAGTTTTTGGAAGGCGAGCTTATTCATGATCTTTTAACCATTTTTGTGAGTGCTAAATTG
GCATCATATGTCAAGTTTTATCAGAATAATAAAGACTTCATTGATTCACTTGGTAATACATATAACATACCAATTCGTTTCTGGATTTTG
GATTCTCACCCTTTCGCTCCCCCTATTTGCTTCTTGAAGCCAACTGCAAATATGGGAATCTTAGTCGGAAAACATGTGGATGCTCAAGGC
AGAATATATTTGCCCTATCTCCAAAACTGGAGCCATCCTAAATCTGTCATTGTTGGATTAATTAAAGAAATGATTGCCAAGTTTCAAGAG
GAACTTCCCATGTATTCTCTATCATCATCTGATGAGGCACGGCAGGTAGACTTGCTAGCCTATATTGCAAAAATCACTGAAGGTGTTTCA
GATACAAATTCAAAGAGCTGGGCAAATCATGAGAATAAAACAGTCAATAAAATTACTGTGGTTGGAGGTGGAGAACTCGGTATTGCCTGC
ACATTAGCAATTTCAGCAAAGGGTATTGCAGACAGGCTTGTCCTCTTAGACCTCTCAGAAGGGACTAAAGGAGCCACGATGGACCTTGAA
ATCTTCAACCTTCCTAATGTGGAGATCAGCAAAGATTTGTCTGCCTCTGCTCATTCCAAGGTGGTGATCTTCACAGTCAACTCTTTGGGT
AGTTCTCAGTCGTACCTTGATGTGGTACAGAGCAATGTGGATATGTTCAGAGCCCTTGTCCCAGCTCTGGGACATTATAGTCAACACAGT
GTCCTGCTCGTTGCATCTCAACCAGTGGAAATCATGACCTATGTAACATGGAAACTGAGTACATTTCCTGCAAATCGAGTGATCGGAATT
GGATGTAATCTGGATTCACAGAGATTACAGTATATTATTACAAATGTTTTGAAGGCACAGACTTCAGGCAAAGAAGTATGGGTTATTGGC
GAGCAAGGAGAAGACAAAGTGCTCACATGGAGTGGCCAAGAAGAAGTAGTGAGTCATACCTCTCAAGTGCAGCTGTCCAACAGAGCCATG
GAACTGCTAAGAGTAAAAGGTCAAAGATCCTGGTCTGTTGGACTATCAGTAGCTGACATGGTTGACAGTATTGTAAACAATAAGAAGAAA
GTGCATTCTGTATCAGCTTTAGCAAAGGGATATTATGATATAAATAGTGAAGTGTTTTTAAGTTTGCCTTGCATCCTTGGAACCAATGGA
GTATCTGAAGTTATCAAAACCACACTGAAAGAAGATACAGTTACTGAGAAACTCCAAAGCAGTGCATCCTCAATCCACAGTCTCCAACAA
CAGTTAAAACTTTGATTCTCAAATGCAATTTGAGAGGCTGGACTTCTACCTAAAGGGAAAAGTCATTTAATTTTACCTATATATAGGTTT
GAGGATTTCTGTATCCTGCTACTTACTTTTACAAACTGCTTGGTTAAAGTAGAGGGTTTCTTGATTAGCTTTGTGATGTAAATCCTTAAG
GAGTTATACAAGGAGGGGAAAAATTAATTTTATTTGGGGTTCTTGAGATATCTATGCTGTTCTTTAAATCTACAGCAGGGGTAAACATTC
ATCTGCAGTGTGCATCAATTTAAATCATATATCCTAAACTAAAAGCACAATTCATACTTCGGGAATATTTTATAAGTAATATATCTTTAA
AAGAAAATTACCCTTTGACTTTTATAATCAACATAAGTTCCAGGCCCAGTATGGATTTACAAAATCTGTGTCAGTTGTACATTCACAGGA
TCCACAGCTTAAGTTACTAATGTTTCTTGTGTAAAATCCTGTTGGTAGTAATAGTAAAGCATTGTATTTCCCTTCTTCAAATTAATTACC
TACCAAAAAATGGAAAAGAATTTTACATGCACTTTAAAATAGTAAAATGGAAAGTGAATTTTTAAAATATATGCATTAAAAGTTTACTTT
AATTTCCAGTGGGACTTCCTTTATGAAATTTTCCATAACCTCTTCCTGGAGTATTACAAGATCTCCAACATCTCATAAACTAATTGTGAT
ATTAGTGGAACCATAAGCAAATATATATTTTTAGTGGAAATAGATTATGAATGAAAGCCAAGCACCTTACTTTAAAGCCAAAATATGAGA
TTTTCATTAAAAACATTGGTCATAATAGGGAGAGGTTTTTTATTTGTTCTGAGCAAATCCTTTAACCTCTCCTGATGATACAGTTCAGAG
TACACACACTTTGGTGATGGATCAAGAGCAATATTTTCTTATGTGAAAGATAGCTTATTATTACTATTGTGACATACAACTAATAGTAAC
AGTTAACATCAACACTTCATATATACCAGGCAGCATGATAAGCACTTTATTATTTTACTGAATCCTCACAACAGACCACTGAGGTAGGGA
CTATTGCCATCATCATTTTATAAAAGGAAATTGAGGTTTAGTCCTCAAGAAGTCTTGGCTATTAAGGGGCACTTATCCATACAACCTCTA
CTTTTTCTAGGCACTAAAAGGGGGAAAAGGCTTAATAGCCAAAATAGTTATCAAAAGACCCTAAAGCTGGGGTCCTGTACACCATGAAAG
GATTACTTTCATTCTCATGTAAGGGCATGCTTTTATAAAAAACAAACATGGGCTAGGCGCAGTGACTCACGCCTGTAATCCCAGCACCTT
GGGAGGCTGAGGCGGGCAGATCACGAGGTCAGGAGATTGAGATCATCCTGGCTAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAA
AGTTAGCCAGGCGTGGTGGCAGGTGCCTGTAGTCCCAGCTACTCGGAAGGCTGAGGCAAGAGAATGGCGTGAACCCGGTAGGTGGAGCTT
GCAGTGAGCAGAGATCGCGCCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCCGTCTCAAAAAAAAAAAAAAAAAGTTTAAAAATTA
GCCAGGTGTGGTGATGTGCACCTGTAGTTCCAGCTACTCAGGAGGGTGAGGCAGGAGGATCACTTGAGCCCAGAAGTTCAAGATTGCAAT
GAGCTATGATCATGCTACTGCACTCCAGCCTAGGCAACAGAGTGAGACCCTGTCTCTAAAAAAATAAAAATAAAGCAAGCATATAATAGG
TTAATCCAGATGGAGTTAGGAGGGTTTATAAGGGCAGACACATCCTAGTAAAGAGGAAATAGGCAAACTAATGCTGTTTTAGTGTAATAA
GGAATGCTTATAATGATGAACTTTAGTCATAAAGAAAAGGTGAAATTATATTCAGTAACCCATGTTAGGAAAGCAGAAAACTATTTAATA
TGCTTGGAAAGATTCCAACCAGAGTTAACTGAATAAAAACCTTGGACATTTGAAGAGAAAAGCATTTAGTTCTATCTAATTTCAATATGC
ACGTGAATTAGTTCATGTTACTCTAACAATGTATTCTTACTGTCCTTTTTTATGAAATAGGAAAGTAAAACTGAAAGAACTATTTCTTGT
GTTTTTAAAACTAGCCTTTTCTAATATTTGATATCTAATTAAAGTTAGATAATATGTAATATGCTTTTGAACAATAATCTAACCAGAAAA
TATTGTATAATAAATTACCAAGAAATCATTACATTAATTATAAAAGGAACATGTCAATACAACAAATGTTTATTTAACACCTACTGTTAC
TCCAAATACTGTGTTAGAATTTGACTATTCGAAGATGAATAATAGTCTTTGCCCTCTGGAAGGCCACAATGTAGAAGTAATTCTCTGTAT
CAGATATTTCCTTGAGTGTTAAGTGTATTAGTAATCATGTTGTAAATCCCAGTGTAAGTCAAGAAGCAATATCACCACCACCACCTCCCT
ATGATTTTGTGATAATTTGGCATTTTCAATGCTTGTTAACTTTCATGTTTTCATTTTTATGAAATCATGCAGAGCTTGTTATAATTTTTA
GTGGGGTTTGGATTAAAATGCTTTTTTGATGTAGCAGAAGATACATTTTTTCCCATTTTACATTGTTTTCCTTAAATATTAAGAATAATG

>25918_25918_3_EIF3M-UEVLD_EIF3M_chr11_32617593_ENST00000531120_UEVLD_chr11_18591924_ENST00000396197_length(amino acids)=673AA_BP=266
MSVPAFIDISEEDQAAELRAYLKSKGAEISEENSEGGLHVDLAQIIEACDVCLKEDDKDVESVMNSVVSLLLILEPDKQEALIESLCEKL
VKFREGERPSLRLQLLSNLFHGMDKNTPVRYTVYCSLIKVAASCGAIQYIPTELDQVRKWISDWNLTTEKKHTLLRLLYEALVDCKKSDA
ASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKFLEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGNTY
NIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIYLPYLQNWSHPKSVIVGLIKEMIAKFQEELPMYSLSSSDEARQVDLLAY
IAKITEGVSDTNSKSWANHENKTVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEISKDLSASAHSKV
VIFTVNSLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPVEIMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQT
SGKEVWVIGEQGEDKVLTWSGQEEVVSHTSQVQLSNRAMELLRVKGQRSWSVGLSVADMVDSIVNNKKKVHSVSALAKGYYDINSEVFLS

--------------------------------------------------------------
>25918_25918_4_EIF3M-UEVLD_EIF3M_chr11_32617593_ENST00000531120_UEVLD_chr11_18591924_ENST00000543987_length(transcript)=3080nt_BP=862nt
AGTTCCCTTTTCCGGTCGGCGTGGTCTTGCGAGTGGAGTGTCCGCTGTGCCCGGGCCTGCACCATGAGCGTCCCGGCCTTCATCGACATC
AGTGAAGAAGATCAGGCTGCTGAGCTTCGTGCTTATCTGAAATCTAAAGGAGCTGAGATTTCAGAAGAGAACTCGGAAGGTGGACTTCAT
GTTGATTTAGCTCAAATTATTGAAGCCTGTGATGTGTGTCTGAAGGAGGATGATAAAGATGTTGAAAGTGTGATGAACAGTGTGGTATCC
CTACTCTTGATCCTGGAACCAGACAAGCAAGAAGCTTTGATTGAAAGCCTATGTGAAAAGCTGGTCAAATTTCGCGAAGGTGAACGCCCG
TCTCTGAGACTGCAGTTGTTAAGCAACCTTTTCCACGGGATGGATAAGAATACTCCTGTAAGATACACAGTGTATTGCAGCCTTATTAAA
GTGGCAGCATCTTGTGGGGCCATCCAGTACATCCCAACTGAGCTGGATCAAGTTAGAAAATGGATTTCTGACTGGAATCTCACCACTGAA
AAAAAGCACACCCTTTTAAGACTACTTTATGAGGCACTTGTGGATTGTAAGAAGAGTGATGCTGCTTCAAAAGTCATGGTGGAATTGCTC
GGAAGTTACACAGAGGACAATGCTTCCCAGGCTCGAGTTGATGCCCACAGGTGTATTGTACGAGCATTGAAAGATCCAAATGCATTTCTT
TTTGACCACCTTCTTACTTTAAAACCAGTCAAGTTTTTGGAAGGCGAGCTTATTCATGATCTTTTAACCATTTTTGTGAGTGCTAAATTG
GCATCATATGTCAAGTTTTATCAGAATAATAAAGACTTCATTGATTCACTTGGTAATACATATAACATACCAATTCGTTTCTGGATTTTG
GATTCTCACCCTTTCGCTCCCCCTATTTGCTTCTTGAAGCCAACTGCAAATATGGGAATCTTAGTCGGAAAACATGTGGATGCTCAAGGC
AGAATATATTTGCCCTATCTCCAAAACTGGAGCCATCCTAAATCTGTCATTGTTGGATTAATTAAAGAAATGATTGCCAAGTTTCAAGAG
GAACTTCCCATGTATTCTCTATCATCATCTGATGAGGCACGGCAGGTAGACTTGCTAGCCTATATTGCAAAAATCACTGAAGGTGTTTCA
GATACAAATTCAAAGAGCTGGGCAAATCATGAGAATAAAACAGTCAATAAAATTACTGTGGTTGGAGGTGGAGAACTCGGTATTGCCTGC
ACATTAGCAATTTCAGCAAAGGGTATTGCAGACAGGCTTGTCCTCTTAGACCTCTCAGAAGGGACTAAAGGAGCCACGATGGACCTTGAA
ATCTTCAACCTTCCTAATGTGGAGATCAGCAAAGATTTGTCTGCCTCTGCTCATTCCAAGGTGGTGATCTTCACAGTCAACTCTTTGGGT
AGTTCTCAGTCGTACCTTGATGTGGTACAGAGCAATGTGGATATGTTCAGAGCCCTTGTCCCAGCTCTGGGACATTATAGTCAACACAGT
GTCCTGCTCGTTGCATCTCAACCAGTGGAAATCATGACCTATGTAACATGGAAACTGAGTACATTTCCTGCAAATCGAGTGATCGGAATT
GGATGTAATCTGGATTCACAGAGATTACAGTATATTATTACAAATGTTTTGAAGGCACAGACTTCAGGCAAAGAAGTATGGGTTATTGGC
GAGCAAGGAGAAGACAAAGTGCTCACATGGAGTGGCCAAGAAGAAGTAGTGAGTCATACCTCTCAAGTGCAGCTGTCCAACAGGGATATT
ATGATATAAATAGTGAAGTGTTTTTAAGTTTGCCTTGCATCCTTGGAACCAATGGAGTATCTGAAGTTATCAAAACCACACTGAAAGAAG
ATACAGTTACTGAGAAACTCCAAAGCAGTGCATCCTCAATCCACAGTCTCCAACAACAGTTAAAACTTTGATTCTCAAATGCAATTTGAG
AGGCTGGACTTCTACCTAAAGGGAAAAGTCATTTAATTTTACCTATATATAGGTTTGAGGATTTCTGTATCCTGCTACTTACTTTTACAA
ACTGCTTGGTTAAAGTAGAGGGTTTCTTGATTAGCTTTGTGATGTAAATCCTTAAGGAGTTATACAAGGAGGGGAAAAATTAATTTTATT
TGGGGTTCTTGAGATATCTATGCTGTTCTTTAAATCTACAGCAGGGGTAAACATTCATCTGCAGTGTGCATCAATTTAAATCATATATCC
TAAACTAAAAGCACAATTCATACTTCGGGAATATTTTATAAGTAATATATCTTTAAAAGAAAATTACCCTTTGACTTTTATAATCAACAT
AAGTTCCAGGCCCAGTATGGATTTACAAAATCTGTGTCAGTTGTACATTCACAGGATCCACAGCTTAAGTTACTAATGTTTCTTGTGTAA
AATCCTGTTGGTAGTAATAGTAAAGCATTGTATTTCCCTTCTTCAAATTAATTACCTACCAAAAAATGGAAAAGAATTTTACATGCACTT
TAAAATAGTAAAATGGAAAGTGAATTTTTAAAATATATGCATTAAAAGTTTACTTTAATTTCCAGTGGGACTTCCTTTATGAAATTTTCC
ATAACCTCTTCCTGGAGTATTACAAGATCTCCAACATCTCATAAACTAATTGTGATATTAGTGGAACCATAAGCAAATATATATTTTTAG
TGGAAATAGATTATGAATGAAAGCCAAGCACCTTACTTTAAAGCCAAAATATGAGATTTTCATTAAAAACATTGGTCATAATAGGGAGAG
GTTTTTTATTTGTTCTGAGCAAATCCTTTAACCTCTCCTGATGATACAGTTCAGAGTACACACACTTTGGTGATGGATCAAGAGCAATAT
TTTCTTATGTGAAAGATAGCTTATTATTACTATTGTGACATACAACTAATAGTAACAGTTAACATCAACACTTCATATATACCAGGCAGC
ATGATAAGCACTTTATTATTTTACTGAATCCTCACAACAGACCACTGAGGTAGGGACTATTGCCATCATCATTTTATAAAAGGAAATTGA

>25918_25918_4_EIF3M-UEVLD_EIF3M_chr11_32617593_ENST00000531120_UEVLD_chr11_18591924_ENST00000543987_length(amino acids)=581AA_BP=266
MSVPAFIDISEEDQAAELRAYLKSKGAEISEENSEGGLHVDLAQIIEACDVCLKEDDKDVESVMNSVVSLLLILEPDKQEALIESLCEKL
VKFREGERPSLRLQLLSNLFHGMDKNTPVRYTVYCSLIKVAASCGAIQYIPTELDQVRKWISDWNLTTEKKHTLLRLLYEALVDCKKSDA
ASKVMVELLGSYTEDNASQARVDAHRCIVRALKDPNAFLFDHLLTLKPVKFLEGELIHDLLTIFVSAKLASYVKFYQNNKDFIDSLGNTY
NIPIRFWILDSHPFAPPICFLKPTANMGILVGKHVDAQGRIYLPYLQNWSHPKSVIVGLIKEMIAKFQEELPMYSLSSSDEARQVDLLAY
IAKITEGVSDTNSKSWANHENKTVNKITVVGGGELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEISKDLSASAHSKV
VIFTVNSLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPVEIMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQT

--------------------------------------------------------------

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Fusion Gene PPI Analysis for EIF3M-UEVLD


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneEIF3Mchr11:32617593chr11:18591924ENST00000531120+811344_374266.3333333333333375.0HSV-1 and HSV-2


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for EIF3M-UEVLD


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for EIF3M-UEVLD


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource