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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:EIF4A2-ACTR3 (FusionGDB2 ID:25928)

Fusion Gene Summary for EIF4A2-ACTR3

check button Fusion gene summary
Fusion gene informationFusion gene name: EIF4A2-ACTR3
Fusion gene ID: 25928
HgeneTgene
Gene symbol

EIF4A2

ACTR3

Gene ID

1974

10096

Gene nameeukaryotic translation initiation factor 4A2actin related protein 3
SynonymsBM-010|DDX2B|EIF4A|EIF4F|eIF-4A-II|eIF4A-IIARP3
Cytomap

3q27.3

2q14.1

Type of geneprotein-codingprotein-coding
Descriptioneukaryotic initiation factor 4A-IIATP-dependent RNA helicase eIF4A-2actin-related protein 3ARP3 actin related protein 3 homologactin-like protein 3
Modification date2020032220200327
UniProtAcc

Q14240

Q9C0K3

Ensembl transtripts involved in fusion geneENST00000356531, ENST00000323963, 
ENST00000440191, 		ENST00000263238, 
ENST00000535589, ENST00000536059, 
Fusion gene scores* DoF score21 X 21 X 7=308716 X 13 X 7=1456
# samples 2317
** MAII scorelog2(23/3087*10)=-3.74649971667075
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(17/1456*10)=-3.098403704061
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EIF4A2 [Title/Abstract] AND ACTR3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEIF4A2(186502266)-ACTR3(114691856), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneEIF4A2

GO:1900260

negative regulation of RNA-directed 5'-3' RNA polymerase activity

11922617

TgeneACTR3

GO:0034314

Arp2/3 complex-mediated actin nucleation

11741539|17220302

TgeneACTR3

GO:0045944

positive regulation of transcription by RNA polymerase II

17220302


check buttonFusion gene breakpoints across EIF4A2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ACTR3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-06-0238-01AEIF4A2chr3

186502266

+ACTR3chr2

114691856

+


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Fusion Gene ORF analysis for EIF4A2-ACTR3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000356531ENST00000263238EIF4A2chr3

186502266

+ACTR3chr2

114691856

+
5UTR-3CDSENST00000356531ENST00000535589EIF4A2chr3

186502266

+ACTR3chr2

114691856

+
5UTR-3CDSENST00000356531ENST00000536059EIF4A2chr3

186502266

+ACTR3chr2

114691856

+
In-frameENST00000323963ENST00000263238EIF4A2chr3

186502266

+ACTR3chr2

114691856

+
In-frameENST00000323963ENST00000535589EIF4A2chr3

186502266

+ACTR3chr2

114691856

+
In-frameENST00000323963ENST00000536059EIF4A2chr3

186502266

+ACTR3chr2

114691856

+
In-frameENST00000440191ENST00000263238EIF4A2chr3

186502266

+ACTR3chr2

114691856

+
In-frameENST00000440191ENST00000535589EIF4A2chr3

186502266

+ACTR3chr2

114691856

+
In-frameENST00000440191ENST00000536059EIF4A2chr3

186502266

+ACTR3chr2

114691856

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000323963EIF4A2chr3186502266+ENST00000263238ACTR3chr2114691856+610513964963299
ENST00000323963EIF4A2chr3186502266+ENST00000536059ACTR3chr2114691856+107913964963299
ENST00000323963EIF4A2chr3186502266+ENST00000535589ACTR3chr2114691856+110013964963299
ENST00000440191EIF4A2chr3186502266+ENST00000263238ACTR3chr2114691856+607811234936300
ENST00000440191EIF4A2chr3186502266+ENST00000536059ACTR3chr2114691856+105211234936300
ENST00000440191EIF4A2chr3186502266+ENST00000535589ACTR3chr2114691856+107311234936300

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000323963ENST00000263238EIF4A2chr3186502266+ACTR3chr2114691856+0.0002238420.9997762
ENST00000323963ENST00000536059EIF4A2chr3186502266+ACTR3chr2114691856+0.000694470.9993055
ENST00000323963ENST00000535589EIF4A2chr3186502266+ACTR3chr2114691856+0.0007008120.99929917
ENST00000440191ENST00000263238EIF4A2chr3186502266+ACTR3chr2114691856+9.05E-050.9999094
ENST00000440191ENST00000536059EIF4A2chr3186502266+ACTR3chr2114691856+0.000502340.99949765
ENST00000440191ENST00000535589EIF4A2chr3186502266+ACTR3chr2114691856+0.0005060360.99949396

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Fusion Genomic Features for EIF4A2-ACTR3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
EIF4A2chr3186502266+ACTR3chr2114691855+0.0035345490.99646544
EIF4A2chr3186502266+ACTR3chr2114691855+0.0035345490.99646544

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for EIF4A2-ACTR3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:186502266/chr2:114691856)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
EIF4A2

Q14240

ACTR3

Q9C0K3

FUNCTION: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.FUNCTION: May play a role in the suppression of metastatic potential in lung adenoma carcinoma cells. {ECO:0000269|PubMed:11162478}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEIF4A2chr3:186502266chr2:114691856ENST00000323963+211246_40725408.0DomainHelicase C-terminal
HgeneEIF4A2chr3:186502266chr2:114691856ENST00000323963+21164_23525408.0DomainHelicase ATP-binding
HgeneEIF4A2chr3:186502266chr2:114691856ENST00000440191+211246_40726409.0DomainHelicase C-terminal
HgeneEIF4A2chr3:186502266chr2:114691856ENST00000440191+21164_23526409.0DomainHelicase ATP-binding
HgeneEIF4A2chr3:186502266chr2:114691856ENST00000323963+211183_18625408.0MotifNote=DEAD box
HgeneEIF4A2chr3:186502266chr2:114691856ENST00000323963+21133_6125408.0MotifNote=Q motif
HgeneEIF4A2chr3:186502266chr2:114691856ENST00000440191+211183_18626409.0MotifNote=DEAD box
HgeneEIF4A2chr3:186502266chr2:114691856ENST00000440191+21133_6126409.0MotifNote=Q motif
HgeneEIF4A2chr3:186502266chr2:114691856ENST00000323963+21177_8425408.0Nucleotide bindingATP
HgeneEIF4A2chr3:186502266chr2:114691856ENST00000440191+21177_8426409.0Nucleotide bindingATP


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Fusion Gene Sequence for EIF4A2-ACTR3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>25928_25928_1_EIF4A2-ACTR3_EIF4A2_chr3_186502266_ENST00000323963_ACTR3_chr2_114691856_ENST00000263238_length(transcript)=6105nt_BP=139nt
TATAAAAAACGGGTGGTTGGGCGCCGCTGTCTTTTCAGTCGGGCGCTGAGTGGTTTTTCGGATCATGTCTGGTGGCTCCGCGGATTATAA
CAGAGAACATGGCGGCCCAGAGGGAATGGACCCCGATGGTGTCATCGAGGCTGTTCTTGCCTTAGCTGCATCTTGGACCTCAAGACAAGT
AGGAGAACGGACGTTGACCGGTACGGTAATAGACAGTGGAGATGGTGTCACTCATGTCATTCCTGTGGCTGAAGGGTATGTGATTGGCAG
CTGTATTAAACACATTCCAATCGCAGGACGAGATATAACATATTTTATTCAGCAACTGCTGAGAGACCGAGAAGTAGGAATCCCTCCAGA
ACAATCCTTGGAAACTGCTAAGGCAGTAAAGGAGCGCTATAGTTATGTCTGCCCAGATTTAGTAAAAGAATTTAACAAGTATGATACAGA
TGGGTCAAAATGGATTAAACAGTATACTGGAATCAATGCTATCTCAAAGAAAGAGTTTTCTATCGATGTTGGTTATGAGAGATTTTTGGG
ACCTGAAATCTTTTTTCATCCAGAGTTTGCTAATCCAGACTTTACACAACCTATCTCAGAAGTTGTAGATGAAGTAATTCAGAATTGTCC
TATTGATGTCAGACGTCCTCTCTACAAGAATATTGTCCTCTCTGGAGGTTCAACCATGTTCAGGGACTTTGGACGTCGCTTGCAAAGAGA
TTTGAAAAGAACTGTAGATGCCCGGCTGAAATTAAGTGAGGAATTGAGTGGTGGTAGATTGAAGCCAAAACCTATTGATGTACAAGTCAT
TACACACCACATGCAGCGATATGCAGTTTGGTTTGGAGGATCAATGCTGGCTTCCACGCCTGAGTTCTACCAAGTATGCCACACCAAAAA
GGATTATGAAGAAATTGGACCTAGCATTTGTCGTCACAATCCAGTGTTTGGAGTCATGTCGTAAAATTGGCTTCATAGTTATTGGGGTTA
GGGAGGTGGGGAAGAGATAATCTTTCTGATTACCTGTTTTGTCTGGATGGCTGGTTTTGAGGTTTTAAACCTGACTTGAAATAGTAACAC
CAAACATGATTATACAGGAATATTTTAATAAGTGTATCACCATGCAGATGTAGAAGAGAGCGAAAGTGATTGTGTTTTTCTTTAGATTGA
ATATTTGAATCTTATGTGTAACAAAAAGAAGTGGGTTTTAGTTCTTTCTGTGCCCTGATATTTTGTATATTAATGAATTATCCAAGATTC
GATGGGATTTATCAGTGTGTAGATAGCTCTATAATGCTTGAATTGTACACTTCTAAGTGTGCAGTGCAAGAGCTTGTTTATATTTCATAC
TTTTTATACTTTGAGGAAAAAAAGTCAAAGAAAAATTGTATTTGAGGGAAAAAACCATGACCAAGTAAAGGATAAATTCAAAAAATAGCC
TCATGAGACTTGGCATACACACTCGTGGGATTCCAGTTATTATGGAGTGCTTCCATCCCTCTCCACCCCTTCCCCCCAAAAGGTTTTCTT
TGCAAGTGCTTTTGGAACTAAGAGCTAGTATCTTGGATTAACTGATGCCTGCTAGTGCTTTCTGATTACTCGCATTCTGTTTCTTGCTTT
AAAAGAAGAGTAAAGACAAGAGTGTTGGACCAGTATTGCAGTTCTGTAGTGTCATTTCTTATAAAAAACAAAACAACAACAATAATTTAT
CAAAATTGGCATATTTAAAGCCTAACATTCTAATAAAGGCACAAATTTCTTTTTAATACTTGTTTCAGCCTCTTTAATCTCTTTATAAGT
TAACTAATAAATCTATTTTCTTCAGACTTCTGCAATAGTTCTTTAAAATCACAACAGTTAGCAAGCTGACTTTTGTAATGTGCTCAATAC
AAATACTTGTGAACTTTTAATATGTTGAGTGCTTTCATTTTGATAACTGGATCTCCATTTGATATTTTCATTTGTATAACTCATTTGCAG
TCTGAAAATTTTTTTTAGTGCCAGTCCCTGAACATATCATTGAAAGTTAATTTTCTTTGCATTTTAAAATATCTGGATTATGAAGAAAAA
GTGATGAAAATAAATTAAAACTGAATTACCTTTTCTAATGTTTTTTTTTTTTAAGTAATGTAATTCTATTTTGTTTTTATGTATGTGATA
TCTGTTTCTGTTGAGATTTGGGAGTTATTGAAATCTCTGTAATGTGTATGGTAGAAAATTTCTTGTGACCTTAAAATTTTACCAGTTATT
TATAGAAAGAGAAAATGGGAAATGTTTTATAGGCTTTTTACTAGCAGTATCAGTGAACACTTGAACTCCATTATTCATGAAAATAACACG
TTAGGATTGGAATACGTCTATTCAAAAGTGAAAGAATATAAAGTGTTTAGTTTTTTGTTTTTACTCTAAAGATAGAATTGGGGAGTAAAC
TTCAGTTTTTGTTTAGAGTGGATCTGAATATTTAAAATCCTATAATAATTTTTGTGAATCTTCATTCTTTGAGTATGGGATTGTAAAAGA
CAAACTATATCCTACAGTAGTATCATCATCAGTATCAAAGGTCTCCTTTTTTTACTTGGAAAAGTAATTCACAAACATTATAAAAATACT
ATTCAAACAGTACCAAAGAGTAGATTAGCAAAAGTAAGTTTTTTTCCCTAGCCTGTCTCATTTTTCCATCATTACACAGACTACTTGGAA
TGTCTTAGATGTCCTTGTATTGTAATTTTCTGTGTAGGTAGAAATAAATGTAGCTTTCTTATTTTACACAAATAGGAACTTACTGTATAT
ACTGTTCTGCACTTTGCTTTTATTAAAGATCTTTTGATAAAGAACTATATTGATAAGCAGTAAAGATGTCATGCTCCTGGCCCAATAAAA
TATTGTTAGCATTGTCATAAATATGTCTTTTCCACCGGCGATGGTTGGGTAGTTAAGTGAATAAGCTAGAAAGACATGTTTATAAAGCTA
TTTGATGACAATCTCAGGCATATTTATACAGAGATGTTCTTAACTGTTTGCTACAAAAACATGAAGATCAAAAACTTTCTTGAAGCTTAC
GCTTAACTTATTTGGGGAAACAAAACTCCAGCCCTTCTTGTGTATGTTCTGATATCCCTTTGCTCTACTTTTAGAGGAGTGAACCCTAAT
AGGATGGTAGCAGCATTCTTGTTTCTTTATATCTCTCCTCTGTGATTGTATACCGTTTTTTCAACTTAAAGCAACTTCAGCTGGAAATAT
GTAGAGGTTGGCCAAGGTGAACTAAATAGTCTGTAACATTGATTAGATATCAAGCAACGTGAGCATGGTAGCAAAAGCACTAACTGAAGC
CAGTGATTTAATTTTTAATTCTGATTCTGATAATTGATGATATAGCTCCTCGAACTTTGTTTTTTGTTAAAACTTGGAAAATATATTTGT
ATTATTTTGGACAAATTATTTGAACTCTCTGGACCTTGATTCAATTTATATATAAGGTAAAGGCATTATACTGGATTATCCTGCAATTTC
TTTGAGTTGTTAGAATATAATGTAGCTTATTAATAGCAATATTAGCAGTGTAGTAGATTCTGACTGCAAAACCTAGCCTTTTCTATTGAT
TCATTAGTGGTAGTAAAGGTATTATCTGATTTATCCTTTTTAATAGGCAGTGCTTTGATCAAGTGGGAAATAGTAATGGACAAATAAAAT
CAATGATCATTATCTAACTTGATGCCTGCTTTTCAAAAAGTGAGCAAATTTCACATCTTCACCCTTAGACATTAATTCATGGCACCTACT
ATAAGTACTCATCCTCTTCTTACCTATCTTCTTTTCTATAGGAGATAAAGTGGTTATTCAGACCCCCCAATACAATTTTTTGGTTTGTTT
TCACAGCTACTTAAAAGATTAAAATAACTATTCTTGCAGATATTTCTAGGAATATTTTTAGAAATAATATGAAATACAGGGATAATAGGC
CAATTATGATCTTTATTTTTAATTTCTACAGAAAAGTACTAGAGAATATATCTATAGAAACTTCTTTCAGATAACCCTAAAGATGATACT
AGAATGTTTATAAAATTATTGAGAAGATTATTTGTGTTATAAAGCTTATTTGTACCATAGTAAAGGATGTTTTTGTTCCTCTTCATTCTG
GGCTAATCTGTCAATACTGAAGTCCAGTCTTTTCCCCCTTTTCTTACCAGCTCAACCTTGATTCCTGTGACCCATTCTTTCTGATCTTTC
GTAGTTCATAGTCACCAGGCATGAGTACCTTGGATAGCCCTCTGAAGTCTGTTACCACCCAGATTTCCAACTCGGGTTAATTGGTACTAA
TTCTATTAGCTGGTATAAATAATCCAAAATCTGTGCAGACTCTGGGAGCAAAATGTTCTACTCAGTTTGGAATACTGTGCCTTAAAATAT
ATTTCATTGTAACAGCACCTTGTATATATAGTTGGCCAAGGACAGAGTTGTTACAAGTTACGTGGAACTTTCATAGCAAATCTTGACAGT
AAATACCTTGTTCTTGTATTAGGTCTATATCCTGAATTGACCTTTAGCAAGAATCTTTAGATCTGCTGGAGGGCTGGGATGGCTTTTGGA
CTTCAGTGAAAAAGAATTTCTGCTACTCATTGTTGATAACGCTTCAGTACTGTATAAATGTTTATCCTTTTCCACGTAATTTGTTTTCTA
TGATATGAGAACTTTTATTATAATTTGCCTCAGTCTTGATAGAATCTTAACAAAAATAAAATCTGTGGTCGTCTGAGGTATTCTCCATGC
TATAACCCAGTTTAGCTGATGCATTTGGAGCTTGGGTGCTGAAATTAAATATAACCTATTTGAGTTAAGGATTTATTACTAGTGCTCCAG
TGGTCACAGGAACAATAAAAAAGGAACAACGATAGAAATACGTGATCTAGGAAAGAAGGCAACTGAAAAACCTGAAAGAAAAAAAATGAA
AGATTAAAAGTATACGATATTCTATTTTGATTTAGCAATTACTTGTTTTCTAGTGTTCTGTCAATTTTTGGTGACTTTTATAATTACATT
AAAACTAAGATGCTGAATTAAAATAAAGTTTCTCTTTTATTCAAGCACCAACATTCACTTATATTACCTATATATTGCATCAAGTTTTGA
GCCTTCAATCCCAGAAGCATTGATTGACTGTCTACTGTGGTTCAAGTACTGTGCATAAAGATGAATAAATATTCTGTCCTTGGCTTAGTC
TAATAGTAAAGGCACTCTTAGAGGAGGGACAAATATTTTGCCTAGATAAGATTTGAGAGATAGTAAGTGCGGAATTTCTCTTCATAAAAA
TGGTAGTGTTAGTTGTTTAGAGGGAGAAGTCCAGCTATGTAAGGTGAAAGTGGGGCTTATAAAAGTGGATCTATTGTTTAAAAATTAGTA
CTTTGCTCCTAAAATTTTTACCTAAGTGTTACATCCAACAACAGATGAAAGTAATTCGACAGTAGCATCTGCTTTATTCATTTCATATTT
CCAGTGCCTGACATATTGCTTGGCATATAGTAGTTTAGTGGATGTGTTTGATGAATGAATGAGTAAAAATTATTTTTCATGTTAAAATAA
AACTTTGAATTACATGAGTATACAACTTTTGTTCCTTCAAAATACCCATATTTGTCAAATATGACCGAATTACGACTTTTTTTCTGTTCC
ACTAGTTTCTACCTTAGAAGTGACATTCTGCGTAAGGTAGTGGGGGATTACTAAGTGATCATGACTTTTCTGAAGCAGGTCTTAAATAAT
TATCTAAGCCTTCAGTCATTTCAAAATCTCTGTAGTGTAAATGATCACAGGCTCTAAATCAGATTGTTGTACAAGGTAATTGACATGTCC
TGAAATGTAACATTCAACATTAACAGTAGAAACAGGCCTCATTTCTCCCTCTGGCTTTTATTGATCAATTTTGATATTGTCCAGATCCCA
TGTTAAACCACTTGATTTAGAGATGACTTAATTCTAAACTTCCTCCATTTTTAATTAATAAGATTCAAGGTTGCAGTAAATTGTTAATCT

>25928_25928_1_EIF4A2-ACTR3_EIF4A2_chr3_186502266_ENST00000323963_ACTR3_chr2_114691856_ENST00000263238_length(amino acids)=299AA_BP=25
MSGGSADYNREHGGPEGMDPDGVIEAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLR
DREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEV
VDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKPKPIDVQVITHHMQRYAVWFGGSMLASTPE

--------------------------------------------------------------
>25928_25928_2_EIF4A2-ACTR3_EIF4A2_chr3_186502266_ENST00000323963_ACTR3_chr2_114691856_ENST00000535589_length(transcript)=1100nt_BP=139nt
TATAAAAAACGGGTGGTTGGGCGCCGCTGTCTTTTCAGTCGGGCGCTGAGTGGTTTTTCGGATCATGTCTGGTGGCTCCGCGGATTATAA
CAGAGAACATGGCGGCCCAGAGGGAATGGACCCCGATGGTGTCATCGAGGCTGTTCTTGCCTTAGCTGCATCTTGGACCTCAAGACAAGT
AGGAGAACGGACGTTGACCGGTACGGTAATAGACAGTGGAGATGGTGTCACTCATGTCATTCCTGTGGCTGAAGGGTATGTGATTGGCAG
CTGTATTAAACACATTCCAATCGCAGGACGAGATATAACATATTTTATTCAGCAACTGCTGAGAGACCGAGAAGTAGGAATCCCTCCAGA
ACAATCCTTGGAAACTGCTAAGGCAGTAAAGGAGCGCTATAGTTATGTCTGCCCAGATTTAGTAAAAGAATTTAACAAGTATGATACAGA
TGGGTCAAAATGGATTAAACAGTATACTGGAATCAATGCTATCTCAAAGAAAGAGTTTTCTATCGATGTTGGTTATGAGAGATTTTTGGG
ACCTGAAATCTTTTTTCATCCAGAGTTTGCTAATCCAGACTTTACACAACCTATCTCAGAAGTTGTAGATGAAGTAATTCAGAATTGTCC
TATTGATGTCAGACGTCCTCTCTACAAGAATATTGTCCTCTCTGGAGGTTCAACCATGTTCAGGGACTTTGGACGTCGCTTGCAAAGAGA
TTTGAAAAGAACTGTAGATGCCCGGCTGAAATTAAGTGAGGAATTGAGTGGTGGTAGATTGAAGCCAAAACCTATTGATGTACAAGTCAT
TACACACCACATGCAGCGATATGCAGTTTGGTTTGGAGGATCAATGCTGGCTTCCACGCCTGAGTTCTACCAAGTATGCCACACCAAAAA
GGATTATGAAGAAATTGGACCTAGCATTTGTCGTCACAATCCAGTGTTTGGAGTCATGTCGTAAAATTGGCTTCATAGTTATTGGGGTTA
GGGAGGTGGGGAAGAGATAATCTTTCTGATTACCTGTTTTGTCTGGATGGCTGGTTTTGAGGTTTTAAACCTGACTTGAAATAGTAACAC

>25928_25928_2_EIF4A2-ACTR3_EIF4A2_chr3_186502266_ENST00000323963_ACTR3_chr2_114691856_ENST00000535589_length(amino acids)=299AA_BP=25
MSGGSADYNREHGGPEGMDPDGVIEAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLR
DREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEV
VDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKPKPIDVQVITHHMQRYAVWFGGSMLASTPE

--------------------------------------------------------------
>25928_25928_3_EIF4A2-ACTR3_EIF4A2_chr3_186502266_ENST00000323963_ACTR3_chr2_114691856_ENST00000536059_length(transcript)=1079nt_BP=139nt
TATAAAAAACGGGTGGTTGGGCGCCGCTGTCTTTTCAGTCGGGCGCTGAGTGGTTTTTCGGATCATGTCTGGTGGCTCCGCGGATTATAA
CAGAGAACATGGCGGCCCAGAGGGAATGGACCCCGATGGTGTCATCGAGGCTGTTCTTGCCTTAGCTGCATCTTGGACCTCAAGACAAGT
AGGAGAACGGACGTTGACCGGTACGGTAATAGACAGTGGAGATGGTGTCACTCATGTCATTCCTGTGGCTGAAGGGTATGTGATTGGCAG
CTGTATTAAACACATTCCAATCGCAGGACGAGATATAACATATTTTATTCAGCAACTGCTGAGAGACCGAGAAGTAGGAATCCCTCCAGA
ACAATCCTTGGAAACTGCTAAGGCAGTAAAGGAGCGCTATAGTTATGTCTGCCCAGATTTAGTAAAAGAATTTAACAAGTATGATACAGA
TGGGTCAAAATGGATTAAACAGTATACTGGAATCAATGCTATCTCAAAGAAAGAGTTTTCTATCGATGTTGGTTATGAGAGATTTTTGGG
ACCTGAAATCTTTTTTCATCCAGAGTTTGCTAATCCAGACTTTACACAACCTATCTCAGAAGTTGTAGATGAAGTAATTCAGAATTGTCC
TATTGATGTCAGACGTCCTCTCTACAAGAATATTGTCCTCTCTGGAGGTTCAACCATGTTCAGGGACTTTGGACGTCGCTTGCAAAGAGA
TTTGAAAAGAACTGTAGATGCCCGGCTGAAATTAAGTGAGGAATTGAGTGGTGGTAGATTGAAGCCAAAACCTATTGATGTACAAGTCAT
TACACACCACATGCAGCGATATGCAGTTTGGTTTGGAGGATCAATGCTGGCTTCCACGCCTGAGTTCTACCAAGTATGCCACACCAAAAA
GGATTATGAAGAAATTGGACCTAGCATTTGTCGTCACAATCCAGTGTTTGGAGTCATGTCGTAAAATTGGCTTCATAGTTATTGGGGTTA

>25928_25928_3_EIF4A2-ACTR3_EIF4A2_chr3_186502266_ENST00000323963_ACTR3_chr2_114691856_ENST00000536059_length(amino acids)=299AA_BP=25
MSGGSADYNREHGGPEGMDPDGVIEAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLLR
DREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISEV
VDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKPKPIDVQVITHHMQRYAVWFGGSMLASTPE

--------------------------------------------------------------
>25928_25928_4_EIF4A2-ACTR3_EIF4A2_chr3_186502266_ENST00000440191_ACTR3_chr2_114691856_ENST00000263238_length(transcript)=6078nt_BP=112nt
CTTTTCAGTCGGGCGCTGAGTGGTTTTTCGGATCATGTCTGGTGGCTCCGCGGATTATAACAGCAGAGAACATGGCGGCCCAGAGGGAAT
GGACCCCGATGGTGTCATCGAGGCTGTTCTTGCCTTAGCTGCATCTTGGACCTCAAGACAAGTAGGAGAACGGACGTTGACCGGTACGGT
AATAGACAGTGGAGATGGTGTCACTCATGTCATTCCTGTGGCTGAAGGGTATGTGATTGGCAGCTGTATTAAACACATTCCAATCGCAGG
ACGAGATATAACATATTTTATTCAGCAACTGCTGAGAGACCGAGAAGTAGGAATCCCTCCAGAACAATCCTTGGAAACTGCTAAGGCAGT
AAAGGAGCGCTATAGTTATGTCTGCCCAGATTTAGTAAAAGAATTTAACAAGTATGATACAGATGGGTCAAAATGGATTAAACAGTATAC
TGGAATCAATGCTATCTCAAAGAAAGAGTTTTCTATCGATGTTGGTTATGAGAGATTTTTGGGACCTGAAATCTTTTTTCATCCAGAGTT
TGCTAATCCAGACTTTACACAACCTATCTCAGAAGTTGTAGATGAAGTAATTCAGAATTGTCCTATTGATGTCAGACGTCCTCTCTACAA
GAATATTGTCCTCTCTGGAGGTTCAACCATGTTCAGGGACTTTGGACGTCGCTTGCAAAGAGATTTGAAAAGAACTGTAGATGCCCGGCT
GAAATTAAGTGAGGAATTGAGTGGTGGTAGATTGAAGCCAAAACCTATTGATGTACAAGTCATTACACACCACATGCAGCGATATGCAGT
TTGGTTTGGAGGATCAATGCTGGCTTCCACGCCTGAGTTCTACCAAGTATGCCACACCAAAAAGGATTATGAAGAAATTGGACCTAGCAT
TTGTCGTCACAATCCAGTGTTTGGAGTCATGTCGTAAAATTGGCTTCATAGTTATTGGGGTTAGGGAGGTGGGGAAGAGATAATCTTTCT
GATTACCTGTTTTGTCTGGATGGCTGGTTTTGAGGTTTTAAACCTGACTTGAAATAGTAACACCAAACATGATTATACAGGAATATTTTA
ATAAGTGTATCACCATGCAGATGTAGAAGAGAGCGAAAGTGATTGTGTTTTTCTTTAGATTGAATATTTGAATCTTATGTGTAACAAAAA
GAAGTGGGTTTTAGTTCTTTCTGTGCCCTGATATTTTGTATATTAATGAATTATCCAAGATTCGATGGGATTTATCAGTGTGTAGATAGC
TCTATAATGCTTGAATTGTACACTTCTAAGTGTGCAGTGCAAGAGCTTGTTTATATTTCATACTTTTTATACTTTGAGGAAAAAAAGTCA
AAGAAAAATTGTATTTGAGGGAAAAAACCATGACCAAGTAAAGGATAAATTCAAAAAATAGCCTCATGAGACTTGGCATACACACTCGTG
GGATTCCAGTTATTATGGAGTGCTTCCATCCCTCTCCACCCCTTCCCCCCAAAAGGTTTTCTTTGCAAGTGCTTTTGGAACTAAGAGCTA
GTATCTTGGATTAACTGATGCCTGCTAGTGCTTTCTGATTACTCGCATTCTGTTTCTTGCTTTAAAAGAAGAGTAAAGACAAGAGTGTTG
GACCAGTATTGCAGTTCTGTAGTGTCATTTCTTATAAAAAACAAAACAACAACAATAATTTATCAAAATTGGCATATTTAAAGCCTAACA
TTCTAATAAAGGCACAAATTTCTTTTTAATACTTGTTTCAGCCTCTTTAATCTCTTTATAAGTTAACTAATAAATCTATTTTCTTCAGAC
TTCTGCAATAGTTCTTTAAAATCACAACAGTTAGCAAGCTGACTTTTGTAATGTGCTCAATACAAATACTTGTGAACTTTTAATATGTTG
AGTGCTTTCATTTTGATAACTGGATCTCCATTTGATATTTTCATTTGTATAACTCATTTGCAGTCTGAAAATTTTTTTTAGTGCCAGTCC
CTGAACATATCATTGAAAGTTAATTTTCTTTGCATTTTAAAATATCTGGATTATGAAGAAAAAGTGATGAAAATAAATTAAAACTGAATT
ACCTTTTCTAATGTTTTTTTTTTTTAAGTAATGTAATTCTATTTTGTTTTTATGTATGTGATATCTGTTTCTGTTGAGATTTGGGAGTTA
TTGAAATCTCTGTAATGTGTATGGTAGAAAATTTCTTGTGACCTTAAAATTTTACCAGTTATTTATAGAAAGAGAAAATGGGAAATGTTT
TATAGGCTTTTTACTAGCAGTATCAGTGAACACTTGAACTCCATTATTCATGAAAATAACACGTTAGGATTGGAATACGTCTATTCAAAA
GTGAAAGAATATAAAGTGTTTAGTTTTTTGTTTTTACTCTAAAGATAGAATTGGGGAGTAAACTTCAGTTTTTGTTTAGAGTGGATCTGA
ATATTTAAAATCCTATAATAATTTTTGTGAATCTTCATTCTTTGAGTATGGGATTGTAAAAGACAAACTATATCCTACAGTAGTATCATC
ATCAGTATCAAAGGTCTCCTTTTTTTACTTGGAAAAGTAATTCACAAACATTATAAAAATACTATTCAAACAGTACCAAAGAGTAGATTA
GCAAAAGTAAGTTTTTTTCCCTAGCCTGTCTCATTTTTCCATCATTACACAGACTACTTGGAATGTCTTAGATGTCCTTGTATTGTAATT
TTCTGTGTAGGTAGAAATAAATGTAGCTTTCTTATTTTACACAAATAGGAACTTACTGTATATACTGTTCTGCACTTTGCTTTTATTAAA
GATCTTTTGATAAAGAACTATATTGATAAGCAGTAAAGATGTCATGCTCCTGGCCCAATAAAATATTGTTAGCATTGTCATAAATATGTC
TTTTCCACCGGCGATGGTTGGGTAGTTAAGTGAATAAGCTAGAAAGACATGTTTATAAAGCTATTTGATGACAATCTCAGGCATATTTAT
ACAGAGATGTTCTTAACTGTTTGCTACAAAAACATGAAGATCAAAAACTTTCTTGAAGCTTACGCTTAACTTATTTGGGGAAACAAAACT
CCAGCCCTTCTTGTGTATGTTCTGATATCCCTTTGCTCTACTTTTAGAGGAGTGAACCCTAATAGGATGGTAGCAGCATTCTTGTTTCTT
TATATCTCTCCTCTGTGATTGTATACCGTTTTTTCAACTTAAAGCAACTTCAGCTGGAAATATGTAGAGGTTGGCCAAGGTGAACTAAAT
AGTCTGTAACATTGATTAGATATCAAGCAACGTGAGCATGGTAGCAAAAGCACTAACTGAAGCCAGTGATTTAATTTTTAATTCTGATTC
TGATAATTGATGATATAGCTCCTCGAACTTTGTTTTTTGTTAAAACTTGGAAAATATATTTGTATTATTTTGGACAAATTATTTGAACTC
TCTGGACCTTGATTCAATTTATATATAAGGTAAAGGCATTATACTGGATTATCCTGCAATTTCTTTGAGTTGTTAGAATATAATGTAGCT
TATTAATAGCAATATTAGCAGTGTAGTAGATTCTGACTGCAAAACCTAGCCTTTTCTATTGATTCATTAGTGGTAGTAAAGGTATTATCT
GATTTATCCTTTTTAATAGGCAGTGCTTTGATCAAGTGGGAAATAGTAATGGACAAATAAAATCAATGATCATTATCTAACTTGATGCCT
GCTTTTCAAAAAGTGAGCAAATTTCACATCTTCACCCTTAGACATTAATTCATGGCACCTACTATAAGTACTCATCCTCTTCTTACCTAT
CTTCTTTTCTATAGGAGATAAAGTGGTTATTCAGACCCCCCAATACAATTTTTTGGTTTGTTTTCACAGCTACTTAAAAGATTAAAATAA
CTATTCTTGCAGATATTTCTAGGAATATTTTTAGAAATAATATGAAATACAGGGATAATAGGCCAATTATGATCTTTATTTTTAATTTCT
ACAGAAAAGTACTAGAGAATATATCTATAGAAACTTCTTTCAGATAACCCTAAAGATGATACTAGAATGTTTATAAAATTATTGAGAAGA
TTATTTGTGTTATAAAGCTTATTTGTACCATAGTAAAGGATGTTTTTGTTCCTCTTCATTCTGGGCTAATCTGTCAATACTGAAGTCCAG
TCTTTTCCCCCTTTTCTTACCAGCTCAACCTTGATTCCTGTGACCCATTCTTTCTGATCTTTCGTAGTTCATAGTCACCAGGCATGAGTA
CCTTGGATAGCCCTCTGAAGTCTGTTACCACCCAGATTTCCAACTCGGGTTAATTGGTACTAATTCTATTAGCTGGTATAAATAATCCAA
AATCTGTGCAGACTCTGGGAGCAAAATGTTCTACTCAGTTTGGAATACTGTGCCTTAAAATATATTTCATTGTAACAGCACCTTGTATAT
ATAGTTGGCCAAGGACAGAGTTGTTACAAGTTACGTGGAACTTTCATAGCAAATCTTGACAGTAAATACCTTGTTCTTGTATTAGGTCTA
TATCCTGAATTGACCTTTAGCAAGAATCTTTAGATCTGCTGGAGGGCTGGGATGGCTTTTGGACTTCAGTGAAAAAGAATTTCTGCTACT
CATTGTTGATAACGCTTCAGTACTGTATAAATGTTTATCCTTTTCCACGTAATTTGTTTTCTATGATATGAGAACTTTTATTATAATTTG
CCTCAGTCTTGATAGAATCTTAACAAAAATAAAATCTGTGGTCGTCTGAGGTATTCTCCATGCTATAACCCAGTTTAGCTGATGCATTTG
GAGCTTGGGTGCTGAAATTAAATATAACCTATTTGAGTTAAGGATTTATTACTAGTGCTCCAGTGGTCACAGGAACAATAAAAAAGGAAC
AACGATAGAAATACGTGATCTAGGAAAGAAGGCAACTGAAAAACCTGAAAGAAAAAAAATGAAAGATTAAAAGTATACGATATTCTATTT
TGATTTAGCAATTACTTGTTTTCTAGTGTTCTGTCAATTTTTGGTGACTTTTATAATTACATTAAAACTAAGATGCTGAATTAAAATAAA
GTTTCTCTTTTATTCAAGCACCAACATTCACTTATATTACCTATATATTGCATCAAGTTTTGAGCCTTCAATCCCAGAAGCATTGATTGA
CTGTCTACTGTGGTTCAAGTACTGTGCATAAAGATGAATAAATATTCTGTCCTTGGCTTAGTCTAATAGTAAAGGCACTCTTAGAGGAGG
GACAAATATTTTGCCTAGATAAGATTTGAGAGATAGTAAGTGCGGAATTTCTCTTCATAAAAATGGTAGTGTTAGTTGTTTAGAGGGAGA
AGTCCAGCTATGTAAGGTGAAAGTGGGGCTTATAAAAGTGGATCTATTGTTTAAAAATTAGTACTTTGCTCCTAAAATTTTTACCTAAGT
GTTACATCCAACAACAGATGAAAGTAATTCGACAGTAGCATCTGCTTTATTCATTTCATATTTCCAGTGCCTGACATATTGCTTGGCATA
TAGTAGTTTAGTGGATGTGTTTGATGAATGAATGAGTAAAAATTATTTTTCATGTTAAAATAAAACTTTGAATTACATGAGTATACAACT
TTTGTTCCTTCAAAATACCCATATTTGTCAAATATGACCGAATTACGACTTTTTTTCTGTTCCACTAGTTTCTACCTTAGAAGTGACATT
CTGCGTAAGGTAGTGGGGGATTACTAAGTGATCATGACTTTTCTGAAGCAGGTCTTAAATAATTATCTAAGCCTTCAGTCATTTCAAAAT
CTCTGTAGTGTAAATGATCACAGGCTCTAAATCAGATTGTTGTACAAGGTAATTGACATGTCCTGAAATGTAACATTCAACATTAACAGT
AGAAACAGGCCTCATTTCTCCCTCTGGCTTTTATTGATCAATTTTGATATTGTCCAGATCCCATGTTAAACCACTTGATTTAGAGATGAC
TTAATTCTAAACTTCCTCCATTTTTAATTAATAAGATTCAAGGTTGCAGTAAATTGTTAATCTTATTTGGAATTATATTAGAAAGTCGAT

>25928_25928_4_EIF4A2-ACTR3_EIF4A2_chr3_186502266_ENST00000440191_ACTR3_chr2_114691856_ENST00000263238_length(amino acids)=300AA_BP=26
MSGGSADYNSREHGGPEGMDPDGVIEAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLL
RDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISE
VVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKPKPIDVQVITHHMQRYAVWFGGSMLASTP

--------------------------------------------------------------
>25928_25928_5_EIF4A2-ACTR3_EIF4A2_chr3_186502266_ENST00000440191_ACTR3_chr2_114691856_ENST00000535589_length(transcript)=1073nt_BP=112nt
CTTTTCAGTCGGGCGCTGAGTGGTTTTTCGGATCATGTCTGGTGGCTCCGCGGATTATAACAGCAGAGAACATGGCGGCCCAGAGGGAAT
GGACCCCGATGGTGTCATCGAGGCTGTTCTTGCCTTAGCTGCATCTTGGACCTCAAGACAAGTAGGAGAACGGACGTTGACCGGTACGGT
AATAGACAGTGGAGATGGTGTCACTCATGTCATTCCTGTGGCTGAAGGGTATGTGATTGGCAGCTGTATTAAACACATTCCAATCGCAGG
ACGAGATATAACATATTTTATTCAGCAACTGCTGAGAGACCGAGAAGTAGGAATCCCTCCAGAACAATCCTTGGAAACTGCTAAGGCAGT
AAAGGAGCGCTATAGTTATGTCTGCCCAGATTTAGTAAAAGAATTTAACAAGTATGATACAGATGGGTCAAAATGGATTAAACAGTATAC
TGGAATCAATGCTATCTCAAAGAAAGAGTTTTCTATCGATGTTGGTTATGAGAGATTTTTGGGACCTGAAATCTTTTTTCATCCAGAGTT
TGCTAATCCAGACTTTACACAACCTATCTCAGAAGTTGTAGATGAAGTAATTCAGAATTGTCCTATTGATGTCAGACGTCCTCTCTACAA
GAATATTGTCCTCTCTGGAGGTTCAACCATGTTCAGGGACTTTGGACGTCGCTTGCAAAGAGATTTGAAAAGAACTGTAGATGCCCGGCT
GAAATTAAGTGAGGAATTGAGTGGTGGTAGATTGAAGCCAAAACCTATTGATGTACAAGTCATTACACACCACATGCAGCGATATGCAGT
TTGGTTTGGAGGATCAATGCTGGCTTCCACGCCTGAGTTCTACCAAGTATGCCACACCAAAAAGGATTATGAAGAAATTGGACCTAGCAT
TTGTCGTCACAATCCAGTGTTTGGAGTCATGTCGTAAAATTGGCTTCATAGTTATTGGGGTTAGGGAGGTGGGGAAGAGATAATCTTTCT

>25928_25928_5_EIF4A2-ACTR3_EIF4A2_chr3_186502266_ENST00000440191_ACTR3_chr2_114691856_ENST00000535589_length(amino acids)=300AA_BP=26
MSGGSADYNSREHGGPEGMDPDGVIEAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLL
RDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISE
VVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKPKPIDVQVITHHMQRYAVWFGGSMLASTP

--------------------------------------------------------------
>25928_25928_6_EIF4A2-ACTR3_EIF4A2_chr3_186502266_ENST00000440191_ACTR3_chr2_114691856_ENST00000536059_length(transcript)=1052nt_BP=112nt
CTTTTCAGTCGGGCGCTGAGTGGTTTTTCGGATCATGTCTGGTGGCTCCGCGGATTATAACAGCAGAGAACATGGCGGCCCAGAGGGAAT
GGACCCCGATGGTGTCATCGAGGCTGTTCTTGCCTTAGCTGCATCTTGGACCTCAAGACAAGTAGGAGAACGGACGTTGACCGGTACGGT
AATAGACAGTGGAGATGGTGTCACTCATGTCATTCCTGTGGCTGAAGGGTATGTGATTGGCAGCTGTATTAAACACATTCCAATCGCAGG
ACGAGATATAACATATTTTATTCAGCAACTGCTGAGAGACCGAGAAGTAGGAATCCCTCCAGAACAATCCTTGGAAACTGCTAAGGCAGT
AAAGGAGCGCTATAGTTATGTCTGCCCAGATTTAGTAAAAGAATTTAACAAGTATGATACAGATGGGTCAAAATGGATTAAACAGTATAC
TGGAATCAATGCTATCTCAAAGAAAGAGTTTTCTATCGATGTTGGTTATGAGAGATTTTTGGGACCTGAAATCTTTTTTCATCCAGAGTT
TGCTAATCCAGACTTTACACAACCTATCTCAGAAGTTGTAGATGAAGTAATTCAGAATTGTCCTATTGATGTCAGACGTCCTCTCTACAA
GAATATTGTCCTCTCTGGAGGTTCAACCATGTTCAGGGACTTTGGACGTCGCTTGCAAAGAGATTTGAAAAGAACTGTAGATGCCCGGCT
GAAATTAAGTGAGGAATTGAGTGGTGGTAGATTGAAGCCAAAACCTATTGATGTACAAGTCATTACACACCACATGCAGCGATATGCAGT
TTGGTTTGGAGGATCAATGCTGGCTTCCACGCCTGAGTTCTACCAAGTATGCCACACCAAAAAGGATTATGAAGAAATTGGACCTAGCAT
TTGTCGTCACAATCCAGTGTTTGGAGTCATGTCGTAAAATTGGCTTCATAGTTATTGGGGTTAGGGAGGTGGGGAAGAGATAATCTTTCT

>25928_25928_6_EIF4A2-ACTR3_EIF4A2_chr3_186502266_ENST00000440191_ACTR3_chr2_114691856_ENST00000536059_length(amino acids)=300AA_BP=26
MSGGSADYNSREHGGPEGMDPDGVIEAVLALAASWTSRQVGERTLTGTVIDSGDGVTHVIPVAEGYVIGSCIKHIPIAGRDITYFIQQLL
RDREVGIPPEQSLETAKAVKERYSYVCPDLVKEFNKYDTDGSKWIKQYTGINAISKKEFSIDVGYERFLGPEIFFHPEFANPDFTQPISE
VVDEVIQNCPIDVRRPLYKNIVLSGGSTMFRDFGRRLQRDLKRTVDARLKLSEELSGGRLKPKPIDVQVITHHMQRYAVWFGGSMLASTP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for EIF4A2-ACTR3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for EIF4A2-ACTR3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for EIF4A2-ACTR3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource