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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:EIF4E2-AGAP1 (FusionGDB2 ID:25968)

Fusion Gene Summary for EIF4E2-AGAP1

check button Fusion gene summary
Fusion gene informationFusion gene name: EIF4E2-AGAP1
Fusion gene ID: 25968
HgeneTgene
Gene symbol

EIF4E2

AGAP1

Gene ID

9470

116987

Gene nameeukaryotic translation initiation factor 4E family member 2ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
Synonyms4E-LP|4EHP|EIF4EL3|IF4e|h4EHPAGAP-1|CENTG2|GGAP1|cnt-g2
Cytomap

2q37.1

2q37.2

Type of geneprotein-codingprotein-coding
Descriptioneukaryotic translation initiation factor 4E type 2eIF-4E type 2eIF4E-like cap-binding proteineIF4E-like protein 4E-LPeukaryotic translation initiation factor 4E homologous proteineukaryotic translation initiation factor 4E-like 3mRNA cap-binding proarf-GAP with GTPase, ANK repeat and PH domain-containing protein 1Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 1GTP-binding and GTPase-activating protein 1centaurin, gamma 2
Modification date2020031320200313
UniProtAcc

O60573

Q9UPQ3

Ensembl transtripts involved in fusion geneENST00000258416, ENST00000409098, 
ENST00000409167, ENST00000409322, 
ENST00000409394, ENST00000409495, 
ENST00000409514, ENST00000479834, 
ENST00000409457, ENST00000428334, 
ENST00000304032, ENST00000336665, 
ENST00000409538, 
Fusion gene scores* DoF score7 X 7 X 5=24515 X 15 X 6=1350
# samples 715
** MAII scorelog2(7/245*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(15/1350*10)=-3.16992500144231
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: EIF4E2 [Title/Abstract] AND AGAP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointEIF4E2(233431924)-AGAP1(236617822), # samples:1
Anticipated loss of major functional domain due to fusion event.EIF4E2-AGAP1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
EIF4E2-AGAP1 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across EIF4E2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across AGAP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-HC-7232EIF4E2chr2

233431924

+AGAP1chr2

236617822

+


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Fusion Gene ORF analysis for EIF4E2-AGAP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000258416ENST00000409457EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
5CDS-intronENST00000258416ENST00000428334EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
5CDS-intronENST00000409098ENST00000409457EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
5CDS-intronENST00000409098ENST00000428334EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
5CDS-intronENST00000409167ENST00000409457EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
5CDS-intronENST00000409167ENST00000428334EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
5CDS-intronENST00000409322ENST00000409457EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
5CDS-intronENST00000409322ENST00000428334EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
5CDS-intronENST00000409394ENST00000409457EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
5CDS-intronENST00000409394ENST00000428334EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
5CDS-intronENST00000409495ENST00000409457EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
5CDS-intronENST00000409495ENST00000428334EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
5CDS-intronENST00000409514ENST00000409457EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
5CDS-intronENST00000409514ENST00000428334EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
Frame-shiftENST00000258416ENST00000304032EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
Frame-shiftENST00000258416ENST00000336665EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
Frame-shiftENST00000258416ENST00000409538EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
Frame-shiftENST00000409098ENST00000304032EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
Frame-shiftENST00000409098ENST00000336665EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
Frame-shiftENST00000409098ENST00000409538EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
Frame-shiftENST00000409322ENST00000304032EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
Frame-shiftENST00000409322ENST00000336665EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
Frame-shiftENST00000409322ENST00000409538EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
Frame-shiftENST00000409394ENST00000304032EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
Frame-shiftENST00000409394ENST00000336665EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
Frame-shiftENST00000409394ENST00000409538EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
Frame-shiftENST00000409495ENST00000304032EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
Frame-shiftENST00000409495ENST00000336665EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
Frame-shiftENST00000409495ENST00000409538EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
Frame-shiftENST00000409514ENST00000304032EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
Frame-shiftENST00000409514ENST00000336665EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
Frame-shiftENST00000409514ENST00000409538EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
In-frameENST00000409167ENST00000304032EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
In-frameENST00000409167ENST00000336665EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
In-frameENST00000409167ENST00000409538EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
intron-3CDSENST00000479834ENST00000304032EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
intron-3CDSENST00000479834ENST00000336665EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
intron-3CDSENST00000479834ENST00000409538EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
intron-intronENST00000479834ENST00000409457EIF4E2chr2

233431924

+AGAP1chr2

236617822

+
intron-intronENST00000479834ENST00000428334EIF4E2chr2

233431924

+AGAP1chr2

236617822

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000409167EIF4E2chr2233431924+ENST00000336665AGAP1chr2236617822+5919123512643486740
ENST00000409167EIF4E2chr2233431924+ENST00000304032AGAP1chr2236617822+11324123512643645793
ENST00000409167EIF4E2chr2233431924+ENST00000409538AGAP1chr2236617822+5919123512643486740

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000409167ENST00000336665EIF4E2chr2233431924+AGAP1chr2236617822+0.0023280750.9976719
ENST00000409167ENST00000304032EIF4E2chr2233431924+AGAP1chr2236617822+0.002213060.9977869
ENST00000409167ENST00000409538EIF4E2chr2233431924+AGAP1chr2236617822+0.0023280750.9976719

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Fusion Genomic Features for EIF4E2-AGAP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
EIF4E2chr2233431924+AGAP1chr2236617822+7.74E-050.99992263
EIF4E2chr2233431924+AGAP1chr2236617822+7.74E-050.99992263

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for EIF4E2-AGAP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:233431924/chr2:236617822)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
EIF4E2

O60573

AGAP1

Q9UPQ3

FUNCTION: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation (PubMed:17368478, PubMed:25624349, PubMed:9582349). Acts as a repressor of translation initiation (PubMed:22751931). In contrast to EIF4E, it is unable to bind eIF4G (EIF4G1, EIF4G2 or EIF4G3), suggesting that it acts by competing with EIF4E and block assembly of eIF4F at the cap (By similarity). In P-bodies, component of a complex that promotes miRNA-mediated translational repression (PubMed:28487484). {ECO:0000250|UniProtKB:Q8BMB3, ECO:0000269|PubMed:17368478, ECO:0000269|PubMed:22751931, ECO:0000269|PubMed:25624349, ECO:0000269|PubMed:28487484, ECO:0000269|PubMed:9582349}.FUNCTION: GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system. {ECO:0000269|PubMed:12640130}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneEIF4E2chr2:233431924chr2:236617822ENST00000258416+67124_125221246.0Region7-methylguanosine-containing mRNA cap binding
HgeneEIF4E2chr2:233431924chr2:236617822ENST00000258416+67150_157221246.0RegionEIF4EBP1/2/3 binding
HgeneEIF4E2chr2:233431924chr2:236617822ENST00000258416+67174_179221246.0Region7-methylguanosine-containing mRNA cap binding
HgeneEIF4E2chr2:233431924chr2:236617822ENST00000258416+67222_224221246.0Region7-methylguanosine-containing mRNA cap binding
HgeneEIF4E2chr2:233431924chr2:236617822ENST00000258416+6754_57221246.0RegionEIF4EBP1/2/3 binding
HgeneEIF4E2chr2:233431924chr2:236617822ENST00000258416+6778_79221246.0Region7-methylguanosine-containing mRNA cap binding
HgeneEIF4E2chr2:233431924chr2:236617822ENST00000258416+6795_99221246.0RegionEIF4EBP1/2/3 binding
TgeneAGAP1chr2:233431924chr2:236617822ENST00000304032018346_58854858.0DomainPH
TgeneAGAP1chr2:233431924chr2:236617822ENST00000304032018609_72954858.0DomainArf-GAP
TgeneAGAP1chr2:233431924chr2:236617822ENST00000336665017346_58854805.0DomainPH
TgeneAGAP1chr2:233431924chr2:236617822ENST00000336665017609_72954805.0DomainArf-GAP
TgeneAGAP1chr2:233431924chr2:236617822ENST00000409457010346_58854406.0DomainPH
TgeneAGAP1chr2:233431924chr2:236617822ENST00000409457010609_72954406.0DomainArf-GAP
TgeneAGAP1chr2:233431924chr2:236617822ENST00000304032018122_12654858.0Nucleotide bindingGTP
TgeneAGAP1chr2:233431924chr2:236617822ENST00000304032018178_18154858.0Nucleotide bindingGTP
TgeneAGAP1chr2:233431924chr2:236617822ENST0000030403201878_8554858.0Nucleotide bindingGTP
TgeneAGAP1chr2:233431924chr2:236617822ENST00000336665017122_12654805.0Nucleotide bindingGTP
TgeneAGAP1chr2:233431924chr2:236617822ENST00000336665017178_18154805.0Nucleotide bindingGTP
TgeneAGAP1chr2:233431924chr2:236617822ENST0000033666501778_8554805.0Nucleotide bindingGTP
TgeneAGAP1chr2:233431924chr2:236617822ENST00000409457010122_12654406.0Nucleotide bindingGTP
TgeneAGAP1chr2:233431924chr2:236617822ENST00000409457010178_18154406.0Nucleotide bindingGTP
TgeneAGAP1chr2:233431924chr2:236617822ENST0000040945701078_8554406.0Nucleotide bindingGTP
TgeneAGAP1chr2:233431924chr2:236617822ENST0000030403201866_27654858.0RegionNote=Small GTPase-like
TgeneAGAP1chr2:233431924chr2:236617822ENST0000033666501766_27654805.0RegionNote=Small GTPase-like
TgeneAGAP1chr2:233431924chr2:236617822ENST0000040945701066_27654406.0RegionNote=Small GTPase-like
TgeneAGAP1chr2:233431924chr2:236617822ENST00000304032018768_79754858.0RepeatNote=ANK 1
TgeneAGAP1chr2:233431924chr2:236617822ENST00000304032018801_83054858.0RepeatNote=ANK 2
TgeneAGAP1chr2:233431924chr2:236617822ENST00000336665017768_79754805.0RepeatNote=ANK 1
TgeneAGAP1chr2:233431924chr2:236617822ENST00000336665017801_83054805.0RepeatNote=ANK 2
TgeneAGAP1chr2:233431924chr2:236617822ENST00000409457010768_79754406.0RepeatNote=ANK 1
TgeneAGAP1chr2:233431924chr2:236617822ENST00000409457010801_83054406.0RepeatNote=ANK 2
TgeneAGAP1chr2:233431924chr2:236617822ENST00000304032018624_64754858.0Zinc fingerC4-type
TgeneAGAP1chr2:233431924chr2:236617822ENST00000336665017624_64754805.0Zinc fingerC4-type
TgeneAGAP1chr2:233431924chr2:236617822ENST00000409457010624_64754406.0Zinc fingerC4-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note


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Fusion Gene Sequence for EIF4E2-AGAP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>25968_25968_1_EIF4E2-AGAP1_EIF4E2_chr2_233431924_ENST00000409167_AGAP1_chr2_236617822_ENST00000304032_length(transcript)=11324nt_BP=1235nt
ACTCCCTGAGGCAGTGGCGACAGCGGCGGCGAGAGGATGAACAACAAGTTCGACGCTTTGAAAGATGATGACAGTGGGGACCATGATCAG
AATGAAGAAAACAGCACACAGAAAGATGGTGAGAAGGAAAAAACGGAACGAGACAAGAATCAGAGCAGTAGCAAGAGAAAGGTGGAGCAG
TTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATG
TGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTG
GCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGTACGTGTTGGGGGGTTATGG
GAGGACGTGTCCCTAAGCTTAGTATAAGTAGATCTGTAGTTGGGCCCAGAGGAATATGGCCGGACAGGAGACTTACTTGTGGAGAAGGGA
CAGACCAGGCCTTCCCTCTAGGGCTTCTGGCTACTTGCTGCAGTTCTTTGTCAGCGAGGCTCCCTGCCACCTATACTACCAGGTGCTTTG
TAGCAGAGAGAGCCCATCTGCAGAAACCCAGTTGTACTACCTGGGCTTGCTTAATTTCTACAGGCTGTCTTGTCTTTCATATGCTAACCA
CTATCTTAAAATGAAAGACAAGTGCTTTTCTTTTTCTTGCTGTTTTTTAAGATAATTTCACCCTGCCCACCCTCACCCCACTTCTGCATG
TCTTTTTAACTTGTTAGCTTCAGTCTATTTTCTTTGTCCTGGGATACTGACTACTTATCAGGAATGACTCCATTTCCTTGTGTATAGAGC
TGACTCTTAGAAGAAGGGGGATAGTGTGTGTGTGAGAGAGCAGAATCAAAGGGAAGCATGAAGGCCACAGGGAAAATAAGCTTGGCAATC
TCCCTAGGACTCAGGGAAATAGAGCTCTCTGTCCACAGTGAGAATCACTGTTAGGCTTGCTCCTCAGTGATTGAGTGTCAGAAGTAAGCT
CAGGCTATTGTGAAAAAGTGTGGGGAGTGGCTGTCAGATTGTCTCAAAGCTGGAGGGAGAGCTAGCCAGCTAAGAGTTAGGACTCTTAGG
TTTAGTTCTCTCATATGGCCCCATACCAATATGTGCCTTTGACAAGTGTCTTTGCAACTTTGCTTATGCCTTCGTGAACAGCCAGGAATG
GACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGTGGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGAC
GGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTTCAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAG
AGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGTGGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCA
GACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAG
TTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAAGCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTAC
ATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGTTGCCCAGAAGATTGTTGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTG
CAAGTCGCTACCTAATTCTCCCAGCCATTCCTCCGTCTGTTCCGCGCAGGTGTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGG
GAGTTTAAGCGACTATTCCTCCTCCGTTCCATCGACTCCCAGCACCAGCCAGAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACAC
GCCCACGCCCGTTCGCAAGCAGTCTAAGCGCCGGTCCAACCTGTTCACCTCTCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCT
GGAGAGTCGTGCGGACAGCATTGGGAGCGGCCGAGCCATCCCAATTAAACAGGGCATGCTGTTGAAGCGAAGTGGCAAATCGTTGAATAA
AGAGTGGAAAAAGAAATATGTCACCCTGTGTGACAATGGCGTGCTGACCTATCATCCCAGTTTACATGATTACATGCAGAATGTTCATGG
TAAGGAGATTGACCTTCTGAGAACCACTGTGAAAGTCCCAGGGAAGAGGCCACCCCGAGCCACGTCAGCCTGCGCACCCATCTCCAGCCC
TAAAACCAATGGCCTATCCAAGGACATGAGCAGTTTACACATCTCACCCAATTCAGGGAATGTCACTAGTGCATCTGGGTCTCAGATGGC
AAGCGGCATCAGCCTGGTCTCCTTCAACAGCCGACCCGACGGCATGCACCAGCGCTCCTACTCAGTCTCCAGTGCCGACCAGTGGAGTGA
GGCTACGGTCATTGCAAACTCGGCCATCAGCAGTGACACAGGGCTGGGTGACTCCGTATGCTCCAGCCCCAGTATCTCCAGCACCACCAG
CCCCAAGCTCGACCCGCCCCCCTCCCCTCACGCCAACAGAAAGAAGCACCGAAGGAAGAAAAGCACTAGCAACTTCAAAGCCGACGGCCT
GTCCGGCACTGCTGAAGAACAAGAAGAAAATTTTGAGTTTATCATTGTGTCCCTCACTGGCCAAACATGGCACTTTGAAGCCACGACGTA
TGAGGAGCGGGACGCCTGGGTCCAAGCCATCGAGAGCCAGATCCTGGCCAGCCTGCAGTCGTGCGAGAGCAGCAAGAACAAGTCCCGGCT
GACGAGCCAGAGCGAGGCCATGGCCCTGCAGTCGATCCGGAACATGCGCGGGAACTCCCACTGTGTGGACTGCGAGACCCAGAATCCCAA
CTGGGCCAGTTTGAACTTGGGAGCCCTCATGTGCATCGAATGCTCAGGGATCCACCGGAATCTTGGCACCCACCTTTCCCGAGTCCGATC
TCTGGACCTGGATGACTGGCCAGTCGAGCTCATCAAGGTGATGTCATCCATCGGGAACGAGCTAGCCAACAGCGTCTGGGAAGAGAGCAG
CCAGGGGCGGACGAAACCATCGGTAGACTCCACAAGGGAAGAGAAGGAACGGTGGATCCGTGCCAAGTACGAGCAGAAGCTCTTCCTGGC
CCCGCTGCCCTGCACGGAGCTGTCCCTGGGCCAGCACCTGCTGCGGGCCACCGCCGACGAGGACCTGCGGACGGCCATCCTGCTGCTGGC
ACACGGCTCCCGGGACGAGGTGAACGAGACCTGCGGGGAGGGAGACGGCCGCACGGCGCTGCATCTGGCCTGCCGCAAGGGGAATGTGGT
CCTGGCGCAGCTCCTGATCTGGTACGGAGTGGACGTCACGGCCCGAGATGCCCACGGGAACACAGCTCTGGCCTACGCCCGGCAGGCCTC
CAGCCAGGAGTGCATCGACGTGCTGCTGCAGTACGGCTGCCCCGACGAGCGCTTCGTGCTCATGGCCACCCCTAACCTGTCCAGGAGAAA
CAATAACCGGAACAACAGCAGTGGGAGGGTGCCCACCATCATCTGAGGAACAGCCGTGCCCGCCTGCTCGCCGCACCTGGGACGCGGCAG
CCTCGCCGCATTCTCGCTCAGAAGTCGCAGCACGTGAGTCCCGTCGCATCCCCTCCCTCTTCCTGGTGGCCACCTCCCTCCCGCCCACCC
ACTCTCACCCCAAACAAAATCACAAAACCTGGACATCCCTCAAGGGGCGAAGAGGCGGCCGGGAGACTGCAGAAGTGGCTCCTTTTCATA
AACTCCCCTAAACCACACACAGGAGAGAGCGACGGGCCTCGGCCCTTTGATGATAGCACATGGCGCAGGACCCTTGTCCTGGTGGCACAA
GGGATGGGGACGCGAGGGGGAGGGGAGGCGAGGAACAAGGAGAAGGGGCAACTTTCCTTAACTGGCAGTTGAGCACATAGTACATTTCCC
CTCTACCAAACGGAACACTTGGATTCCATCTCTTCTCTGAGGAGCTCGACGGCATAAATCAGAAGCAAGCACAGAGTTTGTCAGGTTTGA
AGCCCCTATGATGGTGTGTGTCAAATCAGTTGTAGCTAATCTGTCCAGGGAGAATACTGGCTTCATTACACTTGTACAGCCGAGTTCTTC
CCGCATTACTGCTGTTTAATAGAACGTGATTAGTCATCGCCGAGAAGAAAGCATATTAGCCGAGGAGGTAGTCACGCGGCACGCGCCGGT
GATTGCCACGATGTGATTGCAATACTCTTAGAAGCACCATATTATCCCAGACATGTTCTTTCAAGCCCTTGGAGCCCTCTCTAAATTCAC
TGTCATCATTTAGTATCTGTTTAATTTTTCAGTCCAAAGAGAGGAAATCAGTCGCTGAGTATTATTTGACTCCGGTCTCCTTGGTGCAAA
AACAAAATGGGAAAAATAAATAAGAATAACTCAGAAACTCAAAAGGAAACCACAAATTCAGCTAATAATAGCATTTCGAGTATATTTCGT
AAACTAAGGAAATACACAAAAGGCTGTTTTTTCCGACTGTAAGAGATATTTGATGTCCTTTTGCCGAGGTGGATGTGTTAGTCTCAGGCC
CTCCTGGACCACGTTGCCCAAGTCACACAGGCTTCTGTGTTATGTATTTAGATAAGATGTGTGAAAATATATTTGAATAAAAGAAGTTCA
TAAATATGCATTGATTTTTGTACAGACAAATGGCACCTCTCTTAATTTATAAATTGAACTGGATGTGAACTAATAATGTGCAACTAGTTG
AGATAAGAGGGTTACAGATCATTGTACATGGAAAATATTCCCAGCAGTAAACACTTCCATTAATGTGATCTACGGCTTTTGAAAAGGAGC
ATCTCAGAATAAGATGGTGGTACAATTTGCTTATTAAAATTGAGAAAGAAAAAAAAAGACACACTGGAGTATATTAGAAAGGAAAAAGAA
GGAATGTGGTCTCTCATGATTGAAAGCATGATTTAGATCGGATACGGCTTTTGCTAACCAAGGACCAAGGGACTCTGGCAAGATGGGGTG
GTTTTCCGAATGCCAGACCGAGGTGCCTTACGAAGGCAGCTGCCAATGGTTCTGTGGCACAGACTGGCTCCTGAGAACCCAGACGACCTT
GACCTGGCAGCCCGGCCCTCCACGCTAGTACCTCGCCTGATTTTCCATCGTTGCGGTATCCAGCCGCTTCAGACGTCCGCCGCCTTCAGT
GGTGGTAGTCAAATGTAGTCAACCAAACCACAGCATCCCTTAGGTTAAAAGCAAACGGGGCAGCTTTGCCTAGAGCTCATTGACAGTGTG
ATGGGGGGAGAAGGGTTGTCACAATGGAAGATGAGGACACTAGACTCATGTAGCACAGAAACATGAAGCCACACGCACCGGCAGCCTCCG
GGGTGTTCCTCGCTCTCTCGTATGTTAAACCTTATATTTTATAAGAGTTTTTCCTCTTATTTCACTTTTTAAAAAAAATTAAAGTAGGTG
GGGAAAAAAATAAAGCTTTACACAGAATTTATATGTGGGTAAGTGTTTCATGGAAATTTCTAATCTTAACGAAGCTAAGTGGAGCTCACT
CGTATCCAAAAGTATAACAGGTGCAGAAGCCACAAGTCTGAGAACCTTGACGACAGTTCCATCGTCCTGCCATTTGATTTTTCAGTCTGC
GTTTCATCACTGTGTAGCTATTGTAAATGTGAATAGAAAAAAACAGGTCATTGCCTATTTTTGAAGAACGCGTTGGTGTTCGAGTCCACT
AGACACACTCGCTCCACACAGCCTTCACCGTAGACTCTGTAGTGGACACAGATATAGCATAAATGAAATTGTTAAATTATTTCATTGTAG
TTAATTCCCACTATAGGAATGCTTTATCATAGTGAAGTTTCTTTTGAGAAGAAACGGAACTCCTTGAGGCTTCTCTTTGGGATGTATATG
AGCGTGTACATATTATTCTATGTGTTTATAATATAATATTTTCCCAAATGACTTCTTGTTTCACTTTGCCTTCCACAACCTGAATGCCAG
ATTGGTTTTTTCCCTTCCTGGCCCCCAGCACAAGCTGCCATGACTCCCCCTCAGAAAACACAGCCCCTCCTCTACCATTCTCAGTGATGT
CCATCTGCTCCACTCCGCAGCCACTTTCTAGGGCCCAAGTTTTGGTAGCAGAAGGAAAGGCAGTTTTTGAGGGTCTTTCGAAAAAAAGAA
GACGGGGCAGCTTTGCCCAGAGCTCGTTGGCAGTCTGTTTGTATTTCAGTGTCTAACCAGAAGTCCTTTCTTTGCGGACCGCACTCTCGT
TCCCACTTTCAAGCTAATTACCACCAAGGCTGGGAGAGGCAAGGACTGGGGGCGGAGCTAGGAATAACTCGTTTGAGAAGGGGGTGGAGT
TTTCGTTGTTCATTTCCATGTTCAGTTCTGTGACGTGACGATGACAGATCACCACTGCAGGATCCCCCTCACCTTTCCTGTTCAGAATTA
AAACTCTCCCTTGATGAGAAACAGCCAGCTGAGGGAGGCCCACGAGCGGCCTGTGTAACCCCATGGGTGATCTGGACACATCTGCACCCC
CGCGTTCAGCTTCGCGGAGACTGAACTTGGCGGGGAGTGGAGGGGTGTGGTGCAGACCTGGCTGCAGCAGAAACACCCCGCAGGGACAGT
ACTCTGTGATTCTGACCTCAGGTGCTGGGACGGGCAGATGGTTTCCCCCGCCCAGCACCCCAGTCCTGGTCCCTGGTCCCTCTCTCTGTT
TCATCCCAGGAAATGAGCAGCTCGAGGGTGAGCAAGTGACAAGTTCCTGAGTCACTGGCCCCAAAACCAGGTGCAGTGTCCTGTCTCCCA
AGTGTGTGCACAATGTATATATGCACTGGAAAGGAGGGAGAAGGCAGCGGGTCACTCGCCAATCGCAGGGTTCTCAGACACAGGAGAGAG
CGGGATCTTAATGAATTGCATTTCCTGCAGAGCCTCTAGTGCACAGGCCAGTTCTCGGCAGTGGCTTTTCAGCACAAGGGCCTTGCATTG
AAGCTCCCTCTTCTGAGATTTCACCCAGCCTGATGAGGCCTGCATGGTTCCGGCCTCGTCATCCAGTGTAGATACCAGTCTTCCTATTTT
TGTGACATCTGCACATTTGGGGTCATTCCCTATATCTGCATAGGAGCTATTGCTAACCTTGTTAGGGAGAAACATGGTCTAATGAGAAAG
ACAGACCCCTAGGCTCAGCTGGCCCTGCCATCCTTCCAGAGGATTCCTCTGCAACTCTAGGCAAGCACCCAGCTTCCTGGGCTCTTTTTC
CTCATCTGTGAAACTTGCAGGGTGCAGTGAGGTTTCAAACCAGTGTGATAAGTGTTGGCCTCACACCTGGCCCAGGGGATGCTGGGAGAA
CAGGAGCACTTGTTAATAACAGAAACACTGATGGGACCGAAGCCAGTGCACACACCAGGAAACCTGCCCGTGGCTGACACTGTCCTCCAG
CCTGCATTCTGGGGAGGCTGTGATGGGCACGTTTGCCAACCCCCCCCCCCCAGTAGAGCCCAGGACCCTCCTCTCTCAGCTTGCCAGTGC
CCTGCCCTCCACATGGCGGGGAACAGCATCAATGAGGTCCTTGCTCCCTGAGAGCCTCTCTGGAACCTGCCCACTTTTCTCAACATGTAT
ATTCTGCTTTGTAGTCTGAGGTTGATTTTCTAGAGGCGAGGAAGGGGCTGAGTTCTGCCCTCGTGCTGTTCGCTGGTGCTGATCAGGGCC
AAGACGACCCTTCCCTCTCCCCCACAGCCTGTTGAGGTGCCGTTGACGTGGACAGCGCCCCTCCCTTAAGATGCCCCCTTGCCGTTGCCA
TGAGCCGCTGTGACTCACGCGTGCACTGGGCCTTGCTTGGTGCTCCCCTCCTCCTCCTGTCTGAGATCGGAGCTTGCTGGAGAGCACCCC
AGGTCGCCGTGCTTGGCTGCAGGCCCGTCCCTCTCTCCCCATCCTCGGGTTCCCAGCGTGTTTTGTGCTTGAACTTGGTGGACTCATCTT
ACCCCACAAGAGTGGCCTGCTCAACCTGCAGCCTCCAATGTGCCGTAGGCGCTCTAGGTCCCCGTGGCGCCCAGGACACCAACTCTCCCT
CCCTGCACTTAGGATGTTCTGGAAATGAGAGGAAATCCACATTCCTGCCCCAGGAGGTGGGAAGCCTGGCAACGATGTAGCTTCCCCTGA
GATGCGGTATGATCAGGCCTCAGCAACTACTCAGGAGGCAAAGGTGTTTGGAAAGCAAACCCCAAACCTCCCGGCACGGCATGTGCTCTG
CTTCCGTCCCTCACCGCCTGCACAAGGTCGTTGAGACTTTTCTAGAACTCCCCGGGGTTGTATTTATGGCCTTCAAGCAAACAAATTGAA
AAGCAGTCAAGGAGGAGTTCAGATAGAAAAGTGCTGGAGATACACATCTTTCCTTCAAAGGAAATGTAATTTATTTCCAACCGCTGCCTC
AGACGGGGGTTTCACATGTTGTGAAGTCACATCTTGAATGACTGTCACCCTCATCCTTCCCCAAAAAGCTAAATAAGGGCCTTTGGCATC
AATGCGTGCATTCTCCACCTTTCCGCGGCTTGCGCTTGGATTTCTGAGTGGCTTTCTTCAGGGAGCCCTTGTGGTCATGTGTCTTTAATG
CTGCTCCCCATGCCCCCAGGCCAGGCCAGCACGCTCAGGTGATAGCGAGTGGGGCCAGGAGACCCCCCTGCCCTGCCCAGTGGACAGATC
TGCCCCAGCCCTGCTGTGGGGACGGGCCCTCTATCATTTAACCACATACATTAGGTTGCTTTTCAGCAAAATGTCAGCTTTCCTCCCATT
ATGCAGGAGAGAGAAGGGGCGCAGGTGTATCTCCTTAGAGTACACCTTGGAGCTGGATCACTAAGAAACAGTCCTCAGACTGGTCCTTCC
GACACAGGCAGAGAGTGAACTGGATCGCTGGCCCCTGGGATGCTGCGCTGTCTGTGATTAGAGAGAAGTGGCCAGTGTCCCGTCTGTGAT
TAGACAGAAACCCCTGTGGCAGACTCCTCCCCTCTCCATGAAGAAAGAAATATTTACTTAGATATTACTGTTTCAAAACACAAACTTTAT
TCCCCTTAGAGAAGAAATACTGCCCTTAAATAGACTGTTGAAATATTAATGGCCCCCCCATTTAATCAGTGTGTCTGCGGCTTTCTTCGC
GTCACATGTCCGCATTGGCAGGTGATTCTGGAAAGGGATTCTGGGAAACCAACAAGTCTTTTTTAAATCTTTGAGTTGTATGAGAAAGTA
TTTAAGTTCACCAGTGTAGTAAACACCCACCCCAGAGCAGCGGTAAGCAAACCTAAATCTGAAAACCCATTCTTACTGTCTTTCACCATG
AGATGCTGGTTTTGGTGTAAAATGACAGCACTTGGTTTGGGGTTTTGCACCTGTTGGGTAGAACTGTTCTTGTCTGAGGTCCTCACCCTC
TACAGATGGGCCTCAGGGCCTGGAGGTGGGCAGATGGGGCCAGAGTGGCCAGCAGAGACTTGCATGGGCTCTGAAAGCCCCAGAGCTCAG
GCCTAAGGCTGCTAGGTGAGACCAGCAGGCAGCTGTGGCATCCGACCTTGGGACGCCCAAGCTGGGCAGCCGCTCCATGTGCCCCAAACA
GGATATCCTCATGAATGTGAGGAGAGGCTGGCTCAGGGCTTGGTTTTCATTTTGGCCTGGCACAGGGTACCTGTAGGGAGCACTCCCCCA
ACCTGAGGATGGTGAAACCATATGATAGAGACTCCTTGTCGAAGTCCACATCGGACTGATCTAGAATGCCCCGTGGGGGGATTGCATGGC
CTTTGCCTTGAGATGCAGGTGAAAGAAAGGAACCAAACAAGGCATGAGTGTGTTGGGGAATCTTCCCAGTGGAGCAAACCCCCTTAACAC
ACCAGCTGTTGGGAACAGCTGCCCCTAAATCCAATTAAACCCTCATCTCCCTGGTGCTGAACAGTCTACACTGGCCCAGGAAGCTAACGT
CTGAGCCGCTTGGAGAGCTTTGGTAAACAGAAGACACTGGAAGCCCACTCGGTCAGCAGCTGGGCATGAGGATGTCAGGGGCCTTTGGAC
TTGAGGAAGGACAGTCCAGGTGCATGGAATCCTAATGGGCCTCATGCAGACACTGGAAGCAGCCCAGCCCCCTGCCCAATACCACAGCCC
TGGGGTGTCCCCTGACATTCCTGGAGGTCCCTGGGCAAATGCATTTCCTGCCTGGGTTCTCAGGGTAGGAGAACAGAGAAGGCTCCAAGG
GTGTTGGGAGTGAGCCAGGGGCTGGTCTGGGGAGTGGGTCTCACGCACTGCTCAGGTTGGCACGAGGGACCTCCCCCATCCCAACCCAGC
CCCAAGGGTCCCAGCAGGGCTCTCAGCATGGCTGTTTTGAGGGTACACAGGTGGCTGGAGAGGGGTGGGGCAGTTGCATGGTGGGTGGCA
AAGTGTGCATTTAGAAGCTGCTTCGTGGCGTTAAGAACGGGGGGAGAGGGACCAGCACTGTAACGTTAGAAATAATTCCTTCTTGCAGAC
TTGAAAAGCATCAGTTTCCCTCCCACGGCTGGGTTTTTGTGTCTGAAATACATCTAATTCTCCAGACTGCAGCCCCTCTCAGCCCCGAGC
ACCTGAGCGCTGGGGAGGCCCTTATTGAGCTCAGCCTGGAGAGGGGAGGGTCGCACGGGTCCCGGGGGCAGGTCTCCTGCACTGGCTCTT
CCCTTCTGCCAGCTTGGAATTTGGTTCTCATCTTGCCACAGGGGTGCGTTTCCTAAAGGGCAGCCGGAGCAGCTCAAAGGTGACAACTGA
GATGCATTTCTAGGCAGGGGCAGGGAAGGCCAACCCACCTTGCAGCCAGTTTTCTGTTTCTGTAAATAGCAGTGTATAGAGATGGAAGGG
CAGCGTGGGTGTATCCACAGATGGGTTTAGGTTTTTTTTTTGGATGTTTTCTATTACCTCATTCAGCAACTTTATGTTTCACAATGACTC
AATGATGCTTTATTTATATTGTTTGTACTGTAATTAAAACCATTGACAGACATTTCACTTTGCTTGTTATTTCATATGATCTTGTTTTGA
TTAAATATGCCAGTTTGTATTTTCCTGCCTTGGGATTTTTTTGTGTCCGCTGTACAGTATTCTAAGGGAAAAAGAAAAAGAAAGATGTGT

>25968_25968_1_EIF4E2-AGAP1_EIF4E2_chr2_233431924_ENST00000409167_AGAP1_chr2_236617822_ENST00000304032_length(amino acids)=793AA_BP=
MSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQT
VYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCK
SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLE
SRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK
TNGLSKDMSSLHISPNSGNVTSASGSQMASGISLVSFNSRPDGMHQRSYSVSSADQWSEATVIANSAISSDTGLGDSVCSSPSISSTTSP
KLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAEEQEENFEFIIVSLTGQTWHFEATTYEERDAWVQAIESQILASLQSCESSKNKSRLT
SQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTHLSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQ
GRTKPSVDSTREEKERWIRAKYEQKLFLAPLPCTELSLGQHLLRATADEDLRTAILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVL

--------------------------------------------------------------
>25968_25968_2_EIF4E2-AGAP1_EIF4E2_chr2_233431924_ENST00000409167_AGAP1_chr2_236617822_ENST00000336665_length(transcript)=5919nt_BP=1235nt
ACTCCCTGAGGCAGTGGCGACAGCGGCGGCGAGAGGATGAACAACAAGTTCGACGCTTTGAAAGATGATGACAGTGGGGACCATGATCAG
AATGAAGAAAACAGCACACAGAAAGATGGTGAGAAGGAAAAAACGGAACGAGACAAGAATCAGAGCAGTAGCAAGAGAAAGGTGGAGCAG
TTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATG
TGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTG
GCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGTACGTGTTGGGGGGTTATGG
GAGGACGTGTCCCTAAGCTTAGTATAAGTAGATCTGTAGTTGGGCCCAGAGGAATATGGCCGGACAGGAGACTTACTTGTGGAGAAGGGA
CAGACCAGGCCTTCCCTCTAGGGCTTCTGGCTACTTGCTGCAGTTCTTTGTCAGCGAGGCTCCCTGCCACCTATACTACCAGGTGCTTTG
TAGCAGAGAGAGCCCATCTGCAGAAACCCAGTTGTACTACCTGGGCTTGCTTAATTTCTACAGGCTGTCTTGTCTTTCATATGCTAACCA
CTATCTTAAAATGAAAGACAAGTGCTTTTCTTTTTCTTGCTGTTTTTTAAGATAATTTCACCCTGCCCACCCTCACCCCACTTCTGCATG
TCTTTTTAACTTGTTAGCTTCAGTCTATTTTCTTTGTCCTGGGATACTGACTACTTATCAGGAATGACTCCATTTCCTTGTGTATAGAGC
TGACTCTTAGAAGAAGGGGGATAGTGTGTGTGTGAGAGAGCAGAATCAAAGGGAAGCATGAAGGCCACAGGGAAAATAAGCTTGGCAATC
TCCCTAGGACTCAGGGAAATAGAGCTCTCTGTCCACAGTGAGAATCACTGTTAGGCTTGCTCCTCAGTGATTGAGTGTCAGAAGTAAGCT
CAGGCTATTGTGAAAAAGTGTGGGGAGTGGCTGTCAGATTGTCTCAAAGCTGGAGGGAGAGCTAGCCAGCTAAGAGTTAGGACTCTTAGG
TTTAGTTCTCTCATATGGCCCCATACCAATATGTGCCTTTGACAAGTGTCTTTGCAACTTTGCTTATGCCTTCGTGAACAGCCAGGAATG
GACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGTGGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGAC
GGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTTCAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAG
AGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGTGGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCA
GACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAG
TTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAAGCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTAC
ATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGTTGCCCAGAAGATTGTTGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTG
CAAGTCGCTACCTAATTCTCCCAGCCATTCCTCCGTCTGTTCCGCGCAGGTGTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGG
GAGTTTAAGCGACTATTCCTCCTCCGTTCCATCGACTCCCAGCACCAGCCAGAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACAC
GCCCACGCCCGTTCGCAAGCAGTCTAAGCGCCGGTCCAACCTGTTCACCTCTCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCT
GGAGAGTCGTGCGGACAGCATTGGGAGCGGCCGAGCCATCCCAATTAAACAGGGCATGCTGTTGAAGCGAAGTGGCAAATCGTTGAATAA
AGAGTGGAAAAAGAAATATGTCACCCTGTGTGACAATGGCGTGCTGACCTATCATCCCAGTTTACATGATTACATGCAGAATGTTCATGG
TAAGGAGATTGACCTTCTGAGAACCACTGTGAAAGTCCCAGGGAAGAGGCCACCCCGAGCCACGTCAGCCTGCGCACCCATCTCCAGCCC
TAAAACCAATGGCCTATCCAAGGACATGAGCAGTTTACACATCTCACCCAATTCAGACACAGGGCTGGGTGACTCCGTATGCTCCAGCCC
CAGTATCTCCAGCACCACCAGCCCCAAGCTCGACCCGCCCCCCTCCCCTCACGCCAACAGAAAGAAGCACCGAAGGAAGAAAAGCACTAG
CAACTTCAAAGCCGACGGCCTGTCCGGCACTGCTGAAGAACAAGAAGAAAATTTTGAGTTTATCATTGTGTCCCTCACTGGCCAAACATG
GCACTTTGAAGCCACGACGTATGAGGAGCGGGACGCCTGGGTCCAAGCCATCGAGAGCCAGATCCTGGCCAGCCTGCAGTCGTGCGAGAG
CAGCAAGAACAAGTCCCGGCTGACGAGCCAGAGCGAGGCCATGGCCCTGCAGTCGATCCGGAACATGCGCGGGAACTCCCACTGTGTGGA
CTGCGAGACCCAGAATCCCAACTGGGCCAGTTTGAACTTGGGAGCCCTCATGTGCATCGAATGCTCAGGGATCCACCGGAATCTTGGCAC
CCACCTTTCCCGAGTCCGATCTCTGGACCTGGATGACTGGCCAGTCGAGCTCATCAAGGTGATGTCATCCATCGGGAACGAGCTAGCCAA
CAGCGTCTGGGAAGAGAGCAGCCAGGGGCGGACGAAACCATCGGTAGACTCCACAAGGGAAGAGAAGGAACGGTGGATCCGTGCCAAGTA
CGAGCAGAAGCTCTTCCTGGCCCCGCTGCCCTGCACGGAGCTGTCCCTGGGCCAGCACCTGCTGCGGGCCACCGCCGACGAGGACCTGCG
GACGGCCATCCTGCTGCTGGCACACGGCTCCCGGGACGAGGTGAACGAGACCTGCGGGGAGGGAGACGGCCGCACGGCGCTGCATCTGGC
CTGCCGCAAGGGGAATGTGGTCCTGGCGCAGCTCCTGATCTGGTACGGAGTGGACGTCACGGCCCGAGATGCCCACGGGAACACAGCTCT
GGCCTACGCCCGGCAGGCCTCCAGCCAGGAGTGCATCGACGTGCTGCTGCAGTACGGCTGCCCCGACGAGCGCTTCGTGCTCATGGCCAC
CCCTAACCTGTCCAGGAGAAACAATAACCGGAACAACAGCAGTGGGAGGGTGCCCACCATCATCTGAGGAACAGCCGTGCCCGCCTGCTC
GCCGCACCTGGGACGCGGCAGCCTCGCCGCATTCTCGCTCAGAAGTCGCAGCACGTGAGTCCCGTCGCATCCCCTCCCTCTTCCTGGTGG
CCACCTCCCTCCCGCCCACCCACTCTCACCCCAAACAAAATCACAAAACCTGGACATCCCTCAAGGGGCGAAGAGGCGGCCGGGAGACTG
CAGAAGTGGCTCCTTTTCATAAACTCCCCTAAACCACACACAGGAGAGAGCGACGGGCCTCGGCCCTTTGATGATAGCACATGGCGCAGG
ACCCTTGTCCTGGTGGCACAAGGGATGGGGACGCGAGGGGGAGGGGAGGCGAGGAACAAGGAGAAGGGGCAACTTTCCTTAACTGGCAGT
TGAGCACATAGTACATTTCCCCTCTACCAAACGGAACACTTGGATTCCATCTCTTCTCTGAGGAGCTCGACGGCATAAATCAGAAGCAAG
CACAGAGTTTGTCAGGTTTGAAGCCCCTATGATGGTGTGTGTCAAATCAGTTGTAGCTAATCTGTCCAGGGAGAATACTGGCTTCATTAC
ACTTGTACAGCCGAGTTCTTCCCGCATTACTGCTGTTTAATAGAACGTGATTAGTCATCGCCGAGAAGAAAGCATATTAGCCGAGGAGGT
AGTCACGCGGCACGCGCCGGTGATTGCCACGATGTGATTGCAATACTCTTAGAAGCACCATATTATCCCAGACATGTTCTTTCAAGCCCT
TGGAGCCCTCTCTAAATTCACTGTCATCATTTAGTATCTGTTTAATTTTTCAGTCCAAAGAGAGGAAATCAGTCGCTGAGTATTATTTGA
CTCCGGTCTCCTTGGTGCAAAAACAAAATGGGAAAAATAAATAAGAATAACTCAGAAACTCAAAAGGAAACCACAAATTCAGCTAATAAT
AGCATTTCGAGTATATTTCGTAAACTAAGGAAATACACAAAAGGCTGTTTTTTCCGACTGTAAGAGATATTTGATGTCCTTTTGCCGAGG
TGGATGTGTTAGTCTCAGGCCCTCCTGGACCACGTTGCCCAAGTCACACAGGCTTCTGTGTTATGTATTTAGATAAGATGTGTGAAAATA
TATTTGAATAAAAGAAGTTCATAAATATGCATTGATTTTTGTACAGACAAATGGCACCTCTCTTAATTTATAAATTGAACTGGATGTGAA
CTAATAATGTGCAACTAGTTGAGATAAGAGGGTTACAGATCATTGTACATGGAAAATATTCCCAGCAGTAAACACTTCCATTAATGTGAT
CTACGGCTTTTGAAAAGGAGCATCTCAGAATAAGATGGTGGTACAATTTGCTTATTAAAATTGAGAAAGAAAAAAAAAGACACACTGGAG
TATATTAGAAAGGAAAAAGAAGGAATGTGGTCTCTCATGATTGAAAGCATGATTTAGATCGGATACGGCTTTTGCTAACCAAGGACCAAG
GGACTCTGGCAAGATGGGGTGGTTTTCCGAATGCCAGACCGAGGTGCCTTACGAAGGCAGCTGCCAATGGTTCTGTGGCACAGACTGGCT
CCTGAGAACCCAGACGACCTTGACCTGGCAGCCCGGCCCTCCACGCTAGTACCTCGCCTGATTTTCCATCGTTGCGGTATCCAGCCGCTT
CAGACGTCCGCCGCCTTCAGTGGTGGTAGTCAAATGTAGTCAACCAAACCACAGCATCCCTTAGGTTAAAAGCAAACGGGGCAGCTTTGC
CTAGAGCTCATTGACAGTGTGATGGGGGGAGAAGGGTTGTCACAATGGAAGATGAGGACACTAGACTCATGTAGCACAGAAACATGAAGC
CACACGCACCGGCAGCCTCCGGGGTGTTCCTCGCTCTCTCGTATGTTAAACCTTATATTTTATAAGAGTTTTTCCTCTTATTTCACTTTT
TAAAAAAAATTAAAGTAGGTGGGGAAAAAAATAAAGCTTTACACAGAATTTATATGTGGGTAAGTGTTTCATGGAAATTTCTAATCTTAA
CGAAGCTAAGTGGAGCTCACTCGTATCCAAAAGTATAACAGGTGCAGAAGCCACAAGTCTGAGAACCTTGACGACAGTTCCATCGTCCTG
CCATTTGATTTTTCAGTCTGCGTTTCATCACTGTGTAGCTATTGTAAATGTGAATAGAAAAAAACAGGTCATTGCCTATTTTTGAAGAAC
GCGTTGGTGTTCGAGTCCACTAGACACACTCGCTCCACACAGCCTTCACCGTAGACTCTGTAGTGGACACAGATATAGCATAAATGAAAT
TGTTAAATTATTTCATTGTAGTTAATTCCCACTATAGGAATGCTTTATCATAGTGAAGTTTCTTTTGAGAAGAAACGGAACTCCTTGAGG

>25968_25968_2_EIF4E2-AGAP1_EIF4E2_chr2_233431924_ENST00000409167_AGAP1_chr2_236617822_ENST00000336665_length(amino acids)=740AA_BP=
MSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQT
VYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCK
SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLE
SRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK
TNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAEEQEENFEFIIVSLTGQTWH
FEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTH
LSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKLFLAPLPCTELSLGQHLLRATADEDLRT
AILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATP

--------------------------------------------------------------
>25968_25968_3_EIF4E2-AGAP1_EIF4E2_chr2_233431924_ENST00000409167_AGAP1_chr2_236617822_ENST00000409538_length(transcript)=5919nt_BP=1235nt
ACTCCCTGAGGCAGTGGCGACAGCGGCGGCGAGAGGATGAACAACAAGTTCGACGCTTTGAAAGATGATGACAGTGGGGACCATGATCAG
AATGAAGAAAACAGCACACAGAAAGATGGTGAGAAGGAAAAAACGGAACGAGACAAGAATCAGAGCAGTAGCAAGAGAAAGGTGGAGCAG
TTCTGGAGGTTTTATAGCCACATGGTACGTCCTGGGGACCTGACAGGCCACAGTGACTTCCATCTCTTCAAAGAAGGAATTAAACCCATG
TGGGAGGATGATGCAAATAAAAATGGTGGCAAGTGGATTATTCGGCTGCGGAAGGGCTTGGCCTCCCGTTGCTGGGAGAATCTCATTTTG
GCCATGCTGGGGGAACAGTTCATGGTTGGGGAGGAGATCTGTGGGGCTGTGGTGTCTGTCCGCTTTCAGGTACGTGTTGGGGGGTTATGG
GAGGACGTGTCCCTAAGCTTAGTATAAGTAGATCTGTAGTTGGGCCCAGAGGAATATGGCCGGACAGGAGACTTACTTGTGGAGAAGGGA
CAGACCAGGCCTTCCCTCTAGGGCTTCTGGCTACTTGCTGCAGTTCTTTGTCAGCGAGGCTCCCTGCCACCTATACTACCAGGTGCTTTG
TAGCAGAGAGAGCCCATCTGCAGAAACCCAGTTGTACTACCTGGGCTTGCTTAATTTCTACAGGCTGTCTTGTCTTTCATATGCTAACCA
CTATCTTAAAATGAAAGACAAGTGCTTTTCTTTTTCTTGCTGTTTTTTAAGATAATTTCACCCTGCCCACCCTCACCCCACTTCTGCATG
TCTTTTTAACTTGTTAGCTTCAGTCTATTTTCTTTGTCCTGGGATACTGACTACTTATCAGGAATGACTCCATTTCCTTGTGTATAGAGC
TGACTCTTAGAAGAAGGGGGATAGTGTGTGTGTGAGAGAGCAGAATCAAAGGGAAGCATGAAGGCCACAGGGAAAATAAGCTTGGCAATC
TCCCTAGGACTCAGGGAAATAGAGCTCTCTGTCCACAGTGAGAATCACTGTTAGGCTTGCTCCTCAGTGATTGAGTGTCAGAAGTAAGCT
CAGGCTATTGTGAAAAAGTGTGGGGAGTGGCTGTCAGATTGTCTCAAAGCTGGAGGGAGAGCTAGCCAGCTAAGAGTTAGGACTCTTAGG
TTTAGTTCTCTCATATGGCCCCATACCAATATGTGCCTTTGACAAGTGTCTTTGCAACTTTGCTTATGCCTTCGTGAACAGCCAGGAATG
GACGCTGAGTCGATCTGTCCCGGAGCTCAAAGTGGGAATTGTGGGTAACTTGGCCAGCGGCAAGTCTGCCCTGGTGCACCGGTACCTGAC
GGGCACATATGTCCAGGAGGAGTCTCCGGAAGGTGGCAGGTTCAAGAAAGAGATTGTCGTTGATGGACAGAGCTATCTGCTGCTGATCAG
AGATGAAGGGGGCCCCCCGGAGGCGCAGTTTGCCATGTGGGTGGACGCTGTTATATTTGTCTTCAGCTTGGAGGATGAAATAAGTTTCCA
GACCGTTTACCACTACTACAGTCGAATGGCCAACTATCGGAACACGAGCGAGATTCCTCTGGTTCTGGTGGGAACCCAGGATGCCATAAG
TTCTGCTAACCCGAGGGTCATCGATGACGCCAGGGCGAGGAAGCTCTCCAACGACCTGAAACGGTGCACGTACTACGAGACGTGTGCTAC
ATACGGGCTGAATGTGGAGAGGGTCTTCCAGGACGTTGCCCAGAAGATTGTTGCCACAAGGAAGAAGCAGCAGCTGTCCATAGGACCCTG
CAAGTCGCTACCTAATTCTCCCAGCCATTCCTCCGTCTGTTCCGCGCAGGTGTCTGCCGTGCACATCAGCCAGACAAGTAATGGAGGTGG
GAGTTTAAGCGACTATTCCTCCTCCGTTCCATCGACTCCCAGCACCAGCCAGAAGGAACTTCGGATCGATGTTCCTCCCACTGCCAACAC
GCCCACGCCCGTTCGCAAGCAGTCTAAGCGCCGGTCCAACCTGTTCACCTCTCGGAAAGGGAGCGACCCAGACAAAGAGAAGAAAGGCCT
GGAGAGTCGTGCGGACAGCATTGGGAGCGGCCGAGCCATCCCAATTAAACAGGGCATGCTGTTGAAGCGAAGTGGCAAATCGTTGAATAA
AGAGTGGAAAAAGAAATATGTCACCCTGTGTGACAATGGCGTGCTGACCTATCATCCCAGTTTACATGATTACATGCAGAATGTTCATGG
TAAGGAGATTGACCTTCTGAGAACCACTGTGAAAGTCCCAGGGAAGAGGCCACCCCGAGCCACGTCAGCCTGCGCACCCATCTCCAGCCC
TAAAACCAATGGCCTATCCAAGGACATGAGCAGTTTACACATCTCACCCAATTCAGACACAGGGCTGGGTGACTCCGTATGCTCCAGCCC
CAGTATCTCCAGCACCACCAGCCCCAAGCTCGACCCGCCCCCCTCCCCTCACGCCAACAGAAAGAAGCACCGAAGGAAGAAAAGCACTAG
CAACTTCAAAGCCGACGGCCTGTCCGGCACTGCTGAAGAACAAGAAGAAAATTTTGAGTTTATCATTGTGTCCCTCACTGGCCAAACATG
GCACTTTGAAGCCACGACGTATGAGGAGCGGGACGCCTGGGTCCAAGCCATCGAGAGCCAGATCCTGGCCAGCCTGCAGTCGTGCGAGAG
CAGCAAGAACAAGTCCCGGCTGACGAGCCAGAGCGAGGCCATGGCCCTGCAGTCGATCCGGAACATGCGCGGGAACTCCCACTGTGTGGA
CTGCGAGACCCAGAATCCCAACTGGGCCAGTTTGAACTTGGGAGCCCTCATGTGCATCGAATGCTCAGGGATCCACCGGAATCTTGGCAC
CCACCTTTCCCGAGTCCGATCTCTGGACCTGGATGACTGGCCAGTCGAGCTCATCAAGGTGATGTCATCCATCGGGAACGAGCTAGCCAA
CAGCGTCTGGGAAGAGAGCAGCCAGGGGCGGACGAAACCATCGGTAGACTCCACAAGGGAAGAGAAGGAACGGTGGATCCGTGCCAAGTA
CGAGCAGAAGCTCTTCCTGGCCCCGCTGCCCTGCACGGAGCTGTCCCTGGGCCAGCACCTGCTGCGGGCCACCGCCGACGAGGACCTGCG
GACGGCCATCCTGCTGCTGGCACACGGCTCCCGGGACGAGGTGAACGAGACCTGCGGGGAGGGAGACGGCCGCACGGCGCTGCATCTGGC
CTGCCGCAAGGGGAATGTGGTCCTGGCGCAGCTCCTGATCTGGTACGGAGTGGACGTCACGGCCCGAGATGCCCACGGGAACACAGCTCT
GGCCTACGCCCGGCAGGCCTCCAGCCAGGAGTGCATCGACGTGCTGCTGCAGTACGGCTGCCCCGACGAGCGCTTCGTGCTCATGGCCAC
CCCTAACCTGTCCAGGAGAAACAATAACCGGAACAACAGCAGTGGGAGGGTGCCCACCATCATCTGAGGAACAGCCGTGCCCGCCTGCTC
GCCGCACCTGGGACGCGGCAGCCTCGCCGCATTCTCGCTCAGAAGTCGCAGCACGTGAGTCCCGTCGCATCCCCTCCCTCTTCCTGGTGG
CCACCTCCCTCCCGCCCACCCACTCTCACCCCAAACAAAATCACAAAACCTGGACATCCCTCAAGGGGCGAAGAGGCGGCCGGGAGACTG
CAGAAGTGGCTCCTTTTCATAAACTCCCCTAAACCACACACAGGAGAGAGCGACGGGCCTCGGCCCTTTGATGATAGCACATGGCGCAGG
ACCCTTGTCCTGGTGGCACAAGGGATGGGGACGCGAGGGGGAGGGGAGGCGAGGAACAAGGAGAAGGGGCAACTTTCCTTAACTGGCAGT
TGAGCACATAGTACATTTCCCCTCTACCAAACGGAACACTTGGATTCCATCTCTTCTCTGAGGAGCTCGACGGCATAAATCAGAAGCAAG
CACAGAGTTTGTCAGGTTTGAAGCCCCTATGATGGTGTGTGTCAAATCAGTTGTAGCTAATCTGTCCAGGGAGAATACTGGCTTCATTAC
ACTTGTACAGCCGAGTTCTTCCCGCATTACTGCTGTTTAATAGAACGTGATTAGTCATCGCCGAGAAGAAAGCATATTAGCCGAGGAGGT
AGTCACGCGGCACGCGCCGGTGATTGCCACGATGTGATTGCAATACTCTTAGAAGCACCATATTATCCCAGACATGTTCTTTCAAGCCCT
TGGAGCCCTCTCTAAATTCACTGTCATCATTTAGTATCTGTTTAATTTTTCAGTCCAAAGAGAGGAAATCAGTCGCTGAGTATTATTTGA
CTCCGGTCTCCTTGGTGCAAAAACAAAATGGGAAAAATAAATAAGAATAACTCAGAAACTCAAAAGGAAACCACAAATTCAGCTAATAAT
AGCATTTCGAGTATATTTCGTAAACTAAGGAAATACACAAAAGGCTGTTTTTTCCGACTGTAAGAGATATTTGATGTCCTTTTGCCGAGG
TGGATGTGTTAGTCTCAGGCCCTCCTGGACCACGTTGCCCAAGTCACACAGGCTTCTGTGTTATGTATTTAGATAAGATGTGTGAAAATA
TATTTGAATAAAAGAAGTTCATAAATATGCATTGATTTTTGTACAGACAAATGGCACCTCTCTTAATTTATAAATTGAACTGGATGTGAA
CTAATAATGTGCAACTAGTTGAGATAAGAGGGTTACAGATCATTGTACATGGAAAATATTCCCAGCAGTAAACACTTCCATTAATGTGAT
CTACGGCTTTTGAAAAGGAGCATCTCAGAATAAGATGGTGGTACAATTTGCTTATTAAAATTGAGAAAGAAAAAAAAAGACACACTGGAG
TATATTAGAAAGGAAAAAGAAGGAATGTGGTCTCTCATGATTGAAAGCATGATTTAGATCGGATACGGCTTTTGCTAACCAAGGACCAAG
GGACTCTGGCAAGATGGGGTGGTTTTCCGAATGCCAGACCGAGGTGCCTTACGAAGGCAGCTGCCAATGGTTCTGTGGCACAGACTGGCT
CCTGAGAACCCAGACGACCTTGACCTGGCAGCCCGGCCCTCCACGCTAGTACCTCGCCTGATTTTCCATCGTTGCGGTATCCAGCCGCTT
CAGACGTCCGCCGCCTTCAGTGGTGGTAGTCAAATGTAGTCAACCAAACCACAGCATCCCTTAGGTTAAAAGCAAACGGGGCAGCTTTGC
CTAGAGCTCATTGACAGTGTGATGGGGGGAGAAGGGTTGTCACAATGGAAGATGAGGACACTAGACTCATGTAGCACAGAAACATGAAGC
CACACGCACCGGCAGCCTCCGGGGTGTTCCTCGCTCTCTCGTATGTTAAACCTTATATTTTATAAGAGTTTTTCCTCTTATTTCACTTTT
TAAAAAAAATTAAAGTAGGTGGGGAAAAAAATAAAGCTTTACACAGAATTTATATGTGGGTAAGTGTTTCATGGAAATTTCTAATCTTAA
CGAAGCTAAGTGGAGCTCACTCGTATCCAAAAGTATAACAGGTGCAGAAGCCACAAGTCTGAGAACCTTGACGACAGTTCCATCGTCCTG
CCATTTGATTTTTCAGTCTGCGTTTCATCACTGTGTAGCTATTGTAAATGTGAATAGAAAAAAACAGGTCATTGCCTATTTTTGAAGAAC
GCGTTGGTGTTCGAGTCCACTAGACACACTCGCTCCACACAGCCTTCACCGTAGACTCTGTAGTGGACACAGATATAGCATAAATGAAAT
TGTTAAATTATTTCATTGTAGTTAATTCCCACTATAGGAATGCTTTATCATAGTGAAGTTTCTTTTGAGAAGAAACGGAACTCCTTGAGG

>25968_25968_3_EIF4E2-AGAP1_EIF4E2_chr2_233431924_ENST00000409167_AGAP1_chr2_236617822_ENST00000409538_length(amino acids)=740AA_BP=
MSRSVPELKVGIVGNLASGKSALVHRYLTGTYVQEESPEGGRFKKEIVVDGQSYLLLIRDEGGPPEAQFAMWVDAVIFVFSLEDEISFQT
VYHYYSRMANYRNTSEIPLVLVGTQDAISSANPRVIDDARARKLSNDLKRCTYYETCATYGLNVERVFQDVAQKIVATRKKQQLSIGPCK
SLPNSPSHSSVCSAQVSAVHISQTSNGGGSLSDYSSSVPSTPSTSQKELRIDVPPTANTPTPVRKQSKRRSNLFTSRKGSDPDKEKKGLE
SRADSIGSGRAIPIKQGMLLKRSGKSLNKEWKKKYVTLCDNGVLTYHPSLHDYMQNVHGKEIDLLRTTVKVPGKRPPRATSACAPISSPK
TNGLSKDMSSLHISPNSDTGLGDSVCSSPSISSTTSPKLDPPPSPHANRKKHRRKKSTSNFKADGLSGTAEEQEENFEFIIVSLTGQTWH
FEATTYEERDAWVQAIESQILASLQSCESSKNKSRLTSQSEAMALQSIRNMRGNSHCVDCETQNPNWASLNLGALMCIECSGIHRNLGTH
LSRVRSLDLDDWPVELIKVMSSIGNELANSVWEESSQGRTKPSVDSTREEKERWIRAKYEQKLFLAPLPCTELSLGQHLLRATADEDLRT
AILLLAHGSRDEVNETCGEGDGRTALHLACRKGNVVLAQLLIWYGVDVTARDAHGNTALAYARQASSQECIDVLLQYGCPDERFVLMATP

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Fusion Gene PPI Analysis for EIF4E2-AGAP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for EIF4E2-AGAP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for EIF4E2-AGAP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource